22,531 results match your criteria Nephrolithiasis Urolithiasis


Primary Contributors to Dietary Acid Load in Patients with Urolithiasis.

J Ren Nutr 2022 Jun 22. Epub 2022 Jun 22.

Senior Scientist, University of Wisconsin School of Medicine and Public Health, Department of Urology; and Clinical Nutritionist, UW Health University Hospital and Clinics, 1685 Highland Avenue, 3258 MFCB, Madison, WI 53705-2281.

Objective: In susceptible individuals, high dietary acid load may contribute to the formation of certain types of kidney stones via lowering urine pH and citrate excretion. The objective of this study was to determine the contribution of dietary acid from food groups in people with urolithiasis.

Design: & Methods: Patients with calcium urolithiasis (n=83) who completed food records were used for this retrospective analysis. Read More

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Genetic Variants Involved in the Crystallization Pathway Are Associated with Calcium Nephrolithiasis in the Chinese Han Population.

Genes (Basel) 2022 May 25;13(6). Epub 2022 May 25.

Department of Urology, Huashan Hospital & Institute of Urology, Fudan University, Shanghai 200040, China.

A genome-wide association analysis study (GWAS) in the Japanese population identified 14 significant loci associated with nephrolithiasis. Besides 4 novel loci related to metabolic traits, the 10 remaining loci were associated with kidney or electrolyte-related traits. We aimed to replicate the association of these loci with calcium nephrolithiasis in the Chinese Han population. Read More

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Updated evidence of the safety and efficacy of the miniaturized percutaneous nephrolithotomy with holmium laser lithotripsy for the treatment of recurrent nephrolithiasis.

Eur Rev Med Pharmacol Sci 2022 Jun;26(11):3886-3892

Hanoi Medical College, Hanoi, Vietnam.

Objective: The objective of the present communication is to report the safety and efficacy of applying miniaturized percutaneous nephrolithotomy (mini-PCNL) in Vietnamese patients with recurrent kidney stones using a miniature nephroscope through a 18F metal access sheath.

Patients And Methods: We performed a retrospective cohort study of patients who were diagnosed with recurrent nephrolithiasis and underwent mini-PCNL after previous treatments between 2017 and 2020. Clinical profile, preoperative characteristics, intraoperative events, and postoperative outcomes were obtained from the hospital database. Read More

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Associations of Obesity and Neighborhood Factors With Urinary Stone Parameters.

Am J Prev Med 2022 Jul;63(1S1):S93-S102

Department of Pediatrics, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama.

Introduction: Obesity is associated with kidney stone disease, but it is unknown whether this association differs by SES. This study assessed the extent to which obesity and neighborhood characteristics jointly contribute to urinary risk factors for kidney stone disease.

Methods: This was a retrospective analysis of adult patients with kidney stone disease evaluated with 24-hour urine collection (2001-2020). Read More

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AKI in a Patient with Urinary Tract Infection, Urinary Crystals, and a Bladder Stone.

Kidney360 2022 Apr 3;3(4):790-792. Epub 2022 Mar 3.

Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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Sex Differences and the Risk of Kidney Stones.

Semin Nephrol 2022 Mar;42(2):230-235

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

A significant increase in the prevalence of kidney stones has been observed worldwide. In the past decades, this expansion was more pronounced among women than men. The precise mechanisms involved in the differences in the risk profile of stone disease between men and women have not been fully elucidated. Read More

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Twinkling-guided ultrasound detection of polymethyl methacrylate as a potential breast biopsy marker: a comparative investigation.

Eur Radiol Exp 2022 Jun 17;6(1):26. Epub 2022 Jun 17.

Department of Physiology and Biomedical Engineering, Mayo Clinic, 200 First St, SW, Rochester, MN, 55905, USA.

Since its first description 25 years ago, color Doppler twinkling has been a compelling ultrasound feature in diagnosing urinary stones. While the fundamental cause of twinkling remains elusive, the distinctive twinkling signature is diagnostically valuable in clinical practice. It can be inferred that if an entity twinkles, it empirically has certain physical features. Read More

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The dilemma of 12/14F ureteral access sheath (UAS) usage: a case control study.

BMC Urol 2022 Jun 15;22(1):84. Epub 2022 Jun 15.

Department of Urology, University Hospital Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23562, Lübeck, Germany.

Background: The insertion of a ureteral access sheath (UAS) is a frequent procedure during flexible ureteroscopy (fURS) to facilitate kidney stone treatment. The aim of this study was to investigate the influence of 12/14 French (F) UAS on fURS outcomes.

Methods: We performed a retrospective monocentric analysis of fURS procedures conducted at the Department of Urology (University Hospital Schleswig-Holstein, Lübeck, Germany) for kidney stone treatment via lithotripsy or basket stone retrieval between September 2013 and June 2017. Read More

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Fluconazole in hypercalciuric patients with increased 1,25(OH)D levels: the prospective, randomized, placebo-controlled, double-blind FLUCOLITH trial.

Trials 2022 Jun 16;23(1):499. Epub 2022 Jun 16.

Centre de Référence des Maladies Rénales Rares, filières maladies rares ORKID and ERK-Net, Service de Néphrologie, Rhumatologie et Dermatologie Pédiatriques, Hôpital Femme Mère Enfant, Boulevard Pinel, 69677, Bron, Cedex, France.

Background: Hypercalciuria is one of the most frequent metabolic disorders associated with nephrolithiasis and/or nephrocalcinosis possibly leading to chronic kidney disease (CKD) and bone complications in adults. Orphan diseases with different underlying primary pathophysiology share inappropriately increased 1,25(OH)D levels and hypercalciuria, e.g. Read More

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Decision-making and improvements in health-related quality of life in patients with kidney stones: comparing surgery versus observation using a mixed methods analysis.

Urolithiasis 2022 Jun 14. Epub 2022 Jun 14.

Department of Urology, Vanderbilt University Medical Center, 1161 21st Ave. South, A-1302 Medical Center North, Nashville, TN, 37232-2765, USA.

The experience of patients who choose observation or surgery for kidney stones has not been well established. We compared these patients using qualitative interviews, the Wisconsin Quality of Life questionnaire (WISQOL), and the Cambridge Renal Stone Patient Reported Outcome Measure (CReSP). Adult patients with upper tract urinary calculi for whom observation or intervention were options underwent qualitative interviews at baseline and at 2 months. Read More

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[The assistant effects of porcine fibrin sealant in improving stone clearance rate in flexible ureteroscopy lithotripsy in porcine kidney model].

Zhonghua Yi Xue Za Zhi 2022 Jun;102(22):1660-1665

Department of Urology, the First Affiliated Hospital of Nanchang University, Nanchang 330006, China.

To investigate the feasibility of using a porcine fibrin sealant to wrap and remove kidney calculi fragments through an isolated porcine kidney model. In the isolated porcine kidney stone model (implanted with 100 mg, air dried, ≤1 mm human stone fragments, =6;implanted with 100 mg, air dried, ≤3 mm human stone fragments, =6), the ureteral soft mirror combined with the 12/14Fr UAS was used to test the effect of stone extraction using only two stone extraction methods: basket extraction (control group, ≤1 mm stone fragments, =3; ≤3 mm stone fragments, =3) and basket-sealant extraction (test group, ≤1 mm stone fragments, =3; ≤3 mm stone fragments, =3). Compare the stone removal rate and operation time of the two stone retrieval methods. Read More

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Association Between Healthy Eating Index-2015 and Kidney Stones in American Adults: A Cross-Sectional Analysis of NHANES 2007-2018.

Front Nutr 2022 24;9:820190. Epub 2022 May 24.

Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, China.

Purpose: To explore the association between Healthy Eating Index (HEI)-2015 and kidney stones in an American adult population.

Materials And Methods: National Health and Nutrition Examination Survey (NHANES) datasets from 2007 to 2018 were used. Participants aged ≥ 20 years who reported kidney stone history and dietary recall were included. Read More

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Efficacy of Adjuvant Tamsulosin for Improving the Stone-Free Rate after Extracorporeal Shock Wave Lithotripsy in Renal Stones: A Randomized Controlled Trial.

Int J Clin Pract 2022 31;2022:3757588. Epub 2022 Jan 31.

Universidad de Guanajuato, Leon, Mexico.

Introduction: Extracorporeal shock wave lithotripsy (ESWL) is an effective treatment for urolithiasis. Tamsulosin is capable of causing dilation and facilitating the migration of stones. The aim of this study is to evaluate the efficacy of adjuvant treatment with tamsulosin for improving the stone-free rate after a single session of ESWL in the treatment of kidney stones. Read More

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Application of Suctioning Ureteral Access Sheath during Flexible Ureteroscopy for Renal Stones Decreases the Risk of Postoperative Systemic Inflammatory Response Syndrome.

Int J Clin Pract 2022 12;2022:9354714. Epub 2022 Mar 12.

Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Purpose: To clarify the efficiency and outcomes of suctioning ureteral access sheath (UAS) during flexible ureteroscopic lithotripsy (fURL) for the management of renal stones.

Methods: Between January 2017 and January 2019, a total of 444 patients with renal stones undergoing fURL were divided into suctioning UAS and nonsuctioning UAS groups. The outcomes of patients in both groups were compared using a matched-pair analysis (1 : 1 scenario). Read More

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Primary hyperoxaluria and genetic linkages: an insight into the disease burden from Pakistan.

Urolithiasis 2022 Jun 9. Epub 2022 Jun 9.

Department of Pathology, Sindh Institute of Urology and Transplantation (SIUT), Karachi, Pakistan.

Autosomal recessive disorders are prevalent in Pakistan, a developing South Asian country where consanguineous marriages are common. This study seeks to determine the prevalence of monogenic causes in children presenting with nephrocalcinosis and nephrolithiasis at a dialysis and transplant center in Karachi, Pakistan. A retrospective analysis was conducted in children aged 1-18 years presenting with nephrocalcinosis, between 2010 and 2019. Read More

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Efficacy of PCNL in the resolution of symptoms of nephrolithiasis.

Urolithiasis 2022 Jun 8. Epub 2022 Jun 8.

Department of Urology, AIIMS, Bhubaneshwar, Odisha, India.

Patients undergo Percutaneous Nephrolithotomy (PCNL) for the resolution of pain, but at times, other symptoms such as hematuria, dysuria, nausea, emotional distress, and anxiety are also the presenting symptoms. While pain resolution after successful surgery is generally the focus, the resolution rate of other symptoms after surgery is not described. Our study aims to determine the efficacy of PCNL for the resolution of other symptoms. Read More

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Sex disparities and the risk of urolithiasis: a large cross-sectional study.

Ann Med 2022 Dec;54(1):1627-1635

Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Background: Urolithiasis is one of the most common diseases in urology, with a lifetime prevalence of 14% and is more prevalent in males compared to females. We designed to explore sex disparities in the Chinese population to provide evidence for prevention measures and mechanisms of stone formation.

Materials And Methods: A total of 98232 Chinese individuals who had undergone a comprehensive examination in 2017 were included. Read More

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December 2022

A warning system for urolithiasis via retrograde intrarenal surgery using machine learning: an experimental study.

BMC Urol 2022 Jun 6;22(1):80. Epub 2022 Jun 6.

School of Mechanical Engineering, Yonsei University, Seoul, Republic of Korea.

Background: To develop a warning system that can prevent or minimize laser exposure resulting in kidney and ureter damage during retrograde intrarenal surgery (RIRS) for urolithiasis. Our study builds on the hypothesis that shock waves of different degrees are delivered to the hand of the surgeon depending on whether the laser hits the stone or tissue.

Methods: A surgical environment was simulated for RIRS by filling the body of a raw whole chicken with water and stones from the human body. Read More

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Development of a novel predictive model for a successful stone removal after flexible ureteroscopic lithotripsy based on ipsilateral renal function: a single-centre, retrospective cohort study in China.

BMJ Open 2022 Jun 1;12(6):e059319. Epub 2022 Jun 1.

Department of Urology, Institute of Urology (Laboratory of Reconstructive Urology), West China Hospital, Sichuan University, Chengdu, People's Republic of China

Objectives: The aims of this study were to investigate the effect of preoperative ipsilateral renal function on the success of kidney stone removal with flexible ureteroscopic lithotripsy and to develop a predictive model based on the results.

Design: Retrospective cohort study.

Setting: Data from the 2001-2012 period were collected from the electronic records of West China Hospital, Sichuan University. Read More

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Retrospective analysis of stone basket combined with flexible ureteroscope holmium laser lithotripsy in the treatment of lower calyceal stones.

Authors:
D Jinhua D Wanlin

Eur Rev Med Pharmacol Sci 2022 May;26(10):3430-3436

Department of Urology, Yuechi People's Hospital, Guang'an, Sichuan, China.

Objective: The aim of the study was to investigate the efficacy of stone baskets combined with flexible ureteroscope holmium laser lithotripsy (FURL) in the treatment of lower calyceal stones (LCS).

Patients And Methods: A total of 216 patients with LCS who underwent FURL in our hospital were analyzed retrospectively and divided into observation group (n=129, with stone basket) and control group (n=87, without the stone basket), according to whether the stone basket was used during FURL. The operation time, stone size, stone clearance rate, steinstrasse incidence rate and complication rate were collected and analyzed. Read More

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When should we give up on expectant management for patients with proximal ureteral stones?

Curr Urol 2022 Mar 29;16(1):9-14. Epub 2021 Dec 29.

Department of Urology, Kaplan Medical Center, Rehovot, Israel.

Background: Proximal ureteral stones (PUS) have relatively low rates of spontaneous expulsion. However, some patients do well on expectant management. Our aim was to compare risk factors for surgical intervention in patients with PUS who underwent primary intervention to those subjected to expectant management. Read More

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Pregnancy Outcomes in a Cohort of Patients Who Underwent Double-J Ureteric Stenting-A Single Center Experience.

Medicina (Kaunas) 2022 Apr 29;58(5). Epub 2022 Apr 29.

Department of Obstetrics and Gynecology, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.

: Minimally invasive procedures, such as double-J ureteric stenting, could be a promising therapeutic alternative to conservative management of obstructive urinary tract pathology. We aimed to evaluate the safety and effectiveness of double-J ureteric stenting in pregnant women with ureterohydronephrosis or urolithiasis, along with their infectious complications, and to assess the pregnancy outcomes of this cohort of patients in comparison with a control group. : This observational retrospective study included 52 pregnant patients who underwent double-J ureteric stenting for urologic disorders in the Urology Department of 'C. Read More

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Acute bilateral ureteropelvic junction obstruction as a rare cause of hypertensive crisis: a case report.

J Med Case Rep 2022 May 23;16(1):220. Epub 2022 May 23.

Department of Medicine, Einstein Medical Center Philadelphia, Philadelphia, PA, USA.

Background: Bilateral ureteropelvic junction obstruction is a common cause of secondary hypertension in the pediatric population, often due to congenital malformation. On the other hand, it is less frequently encountered in the adult population and is usually due to an acquired condition, most commonly by a bilaterally obstructing nephrolithiasis causing hydronephrosis and subsequent hypertension. The aim of this study was to investigate and highlight the underlying mechanisms by which acute bilateral ureteropelvic junction obstruction causes hypertensive crisis and why early detection and prompt treatment are necessary to mitigate the effects of elevated blood pressure on target organs. Read More

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Simultaneous Occurrence of Nephrolithiasis, Fanconi Syndrome, and Nephro-osteopathy in a Patient on First-line Antiretroviral Therapy - A Case Report.

Indian J Nephrol 2022 Mar-Apr;32(2):175-178. Epub 2022 Mar 11.

Department of Anaesthesiology, Armed Forces Medical College, Pune, Maharashtra, India.

Tenofovir disoproxil fumarate is part of the first-line antiretroviral therapy and can lead to Fanconi syndrome, acute kidney injury, chronic kidney disease, and reduced bone mineral density. We report the first case of simultaneous occurrence of nephrolithiasis, urolithiasis, Fanconi syndrome, and bone fracture in a 54-year-old lady who presented with pain and inability to bear weight on the right lower limb following a trivial fall. She was diagnosed with human immunodeficiency infection in the year 2000 and was on tenofovir, lamivudine, and efavirenz for the past 6 years. Read More

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Editorial Comment: Validity of a patient-specific percutaneous nephrolithotomy (PCNL) simulated surgical rehearsal platform: impact on patient and surgical outcomes.

Int Braz J Urol 2022 Jul-Aug;48(4):724-725

Unidade de Pesquisa Urogenital - Universidade do Estado do Rio de Janeiro - Uerj, Rio de Janeiro, RJ, Brasil.

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Risk factors for moderate-to-severe postoperative pain after percutaneous nephrolithotomy: a retrospective cohort study.

Sci Rep 2022 May 19;12(1):8366. Epub 2022 May 19.

School of Clinical Medicine, Tsinghua University, Beijing, China.

Percutaneous nephrolithotomy (PCNL) is a minimally invasive procedure for removing renal calculi, while a large number of patients experience acute moderate-to-severe pain despite the analgesia provided. This study aimed to explore the risk factors for postoperative pain after PCNL, which may provide a novel perspective to refine the enhanced recovery after surgery (ERAS) program and to improve clinical outcomes. The clinical data of 331 patients who underwent PCNL in our hospital from September 2020 to February 2021 were retrospectively analyzed. Read More

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Retrospective study of visualized ultra-mini percutaneous nephrolithotripsy vs. flexible ureterorenoscopy for nephrolithiasis patients with 1.5-2.5 cm kidney stones and without hydronephrosis.

Eur Rev Med Pharmacol Sci 2022 May;26(9):3185-3191

Department of Urology, the Affiliated Southeast Hospital of Xiamen University, Zhangzhou, Fujian, China.

Objective: To investigate the safety and efficacy of visualized ultra-mini percutaneous nephrolithotripsy (VUMP) and flexible ureterorenoscopy (FURS) in the treatment of nephrolithiasis patients with 1.5-2.5 cm kidney stones and without hydronephrosis. Read More

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Relationship Between Serum Testosterone Levels and Kidney Stones Prevalence in Men.

Front Endocrinol (Lausanne) 2022 2;13:863675. Epub 2022 May 2.

Department of Urology, Xiangya Hospital, Central South University, Changsha, China.

Background: The role of serum testosterone levels in male renal stone formation remains controversial. This study aimed to evaluate the relationship between serum testosterone levels and kidney stone prevalence in males.

Methods: We conducted a cross-sectional study based on the data from the National Health and Nutrition Examination Survey 2011-2016, which included 6,633 male participants, to investigate the association between testosterone levels and the prevalence of kidney stones. Read More

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Effect of Different Molecular Weights of Chitosan on Formulation and Evaluation of Allopurinol-Loaded Nanoparticles for Kidney Targeting and in Management of Hyperuricemic Nephrolithiasis.

AAPS PharmSciTech 2022 May 16;23(5):144. Epub 2022 May 16.

Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science & Technology, Hisar, Haryana, 125001, India.

Present research study was conducted to formulate kidney-targeted allopurinol (AO)-loaded chitosan nanoparticles (ANPs) for management of hyperuricemic related nephrolithiasis. Different molecular weights of chitosan were used for fabricating ANP formulation by adopting modified ionotropic gelation method. The prepared batches were than evaluated for particle size analysis, entrapment efficiency, transmission electron microscopy, X-ray diffraction, Differential Scanning Calorimetry, in vitro release and in vivo animal study. Read More

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