21,297 results match your criteria Nephrolithiasis Urolithiasis


Kidney stones are common in patients with short bowel syndrome receiving long-term parenteral nutrition. A predictive model for urolithiasis.

JPEN J Parenter Enteral Nutr 2021 May 2. Epub 2021 May 2.

Department of General Intensive Care and Institute for Nutrition Research, Rabin Medical Center, Beilinson Hospital, Petah Tikva, Tel Aviv University, Israel.

Background: In short bowel syndrome (SBS) treated with parenteral nutrition (PN), multiple complications can occur. The etiology of kidney stones may be linked to the underlying disease (mesenteric thrombosis, surgical complications and injury, complications of therapy for cancer, Crohn's disease), metabolic abnormalities resulting from morphological and functional changes in the gastrointestinal tract, and to treatment used. We analyzed all these parameters in a large cohort of patients receiving home parenteral nutrition (HPN), to define the incidence of kidney stones and groups of patients particularly at risk of stone formation. Read More

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Side-by-side evaluation of virtual non-contrast and post-contrast images improves detection of clinically significant urolithiasis on single-phase split bolus dual-energy CT urography.

Br J Radiol 2021 May 16;94(1121):20210013. Epub 2021 Apr 16.

Department of Urology, Clinical Hospital Centre Rijeka, Rijeka, Croatia.

Objectives: Studies show insufficient sensitivity of virtual non-contrast (VNC) reconstructions for stone detection in dual-energy CT urography (DE-CTU). The aim of this study was to investigate if side-by-side-evaluation of both VNC and post-contrast images could increase the sensitivity of single-phase split bolus DE-CTU.

Methods: Consecutive patients with haematuria who underwent split bolus DE-CTU on the same dual-source DE-CT scanner were retrospectively enrolled in the study. Read More

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Editorial Comment: Fluid Intake and Dietary Factors and the Risk of Incident Kidney Stones in UK Biobank: A Population-based Prospective Cohort Study.

Int Braz J Urol 2021 Jul-Aug;47(4):894-895

Divisão de Urologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo. São Paulo, SP, Brasil.

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Methanolic extract of Cucumis melo attenuates ethylene glycol-induced nephrolithiasis in Wistar rats.

Urolithiasis 2021 Apr 9. Epub 2021 Apr 9.

Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.

Evaluation of the effects of methanolic extract of Cucumis melo in ethylene glycol-induced nephrolithiasis on Wistar rats. 0.75% solution of ethylene glycol (EG) in payable water was given to produce nephrolithiasis on Wistar rats. Read More

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RETROSPECTIVE REVIEW OF HISTOLOGIC FINDINGS IN CAPTIVE GILA MONSTERS () AND BEADED LIZARDS ().

J Zoo Wildl Med 2021 Apr;52(1):166-175

Northwest ZooPath, Monroe, WA 98272, USA,

A retrospective study was performed by reviewing all spp. submissions to Northwest ZooPath from 1996 to 2019. Necropsy and biopsy specimens from 106 captive Gila monsters () and 49 captive beaded lizards () were reviewed. Read More

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SKOPE - Study of Ketorolac vs Opioid for Pain after Endoscopy: A Double-Blinded Randomized Control Trial in Patients Undergoing Ureteroscopy.

J Urol 2021 Apr 5:101097JU0000000000001772. Epub 2021 Apr 5.

Cleveland Clinic- Glickman Urological & Kidney Institute.

Purpose: Pain is the leading cause for unplanned emergency department visits and readmissions after ureteroscopy (URS), making post-operative analgesic stewardship a priority given the current opioid epidemic. We conducted a double-blinded, randomized controlled trial (RCT), with non-inferiority design, comparing nonsteroidal anti-inflammatory drugs (NSAIDs) to opiates for postoperative pain control in patients undergoing URS for urolithiasis.

Materials And Methods: Patients were randomized and blinded to either oxycodone (5mg) or ketorolac (10mg), taken as needed, with 3 non-blinded oxycodone rescue pills for breakthrough pain. Read More

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[Single use versus reusable flexible ureteroscopy for the treatment of urolithiasis: a comparative study of perioperative complications].

Urologiia 2021 Mar(1):66-69

Aix-Marseille University, APHM, Conception Academic Hospital, Dept. of Urology and Kidney Transplantation, Marseille, France.

Objective: To compare the perioperative complications of patients who underwent flexible ureteroscopy (fURS) for the treatment of urolithiasis according to the type of ureteroscope used, single-use (suURS) or reusable (rURS) flexible ureteroscope.

Patients And Methods: A retrospective and single-center study was conducted between January 2017 and May 2019, including all fURS performed for nephrolithiasis management. During the study period, 5rURS and 1suURS (UscopePU3022) were available. Read More

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[Determination of calcium metabolism markers concentration in patients with calcium oxalate nephrolithiasis].

Urologiia 2021 Mar(1):60-65

Kuban State Medical University, Krasnodar, Russia.

THE AIM OF THE RESEARCH: to reveal the relationship of various markers of calcium metabolism (osteopontin (OPN), parathyroid hormone-related protein (PTHrP), vitamin D, parathyroid hormone (PTH)) on the course of urolithiasis (Urolithiasis) in patients with calcium oxalate nephrolithiasis.

Materials And Methods: 100 people were examined, the following groups were included: group 1 - patients with calcium oxalate primary nephrolithiasis (n=41), group 2 - with calcium oxalate recurrent nephrolithiasis (n=39). Group 3 included conditionally healthy volunteers (n=20). Read More

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[InsKid Mobile application for the reconstruction of the internal view of the collecting system].

Urologiia 2021 Mar(1):56-59

Department of urology of North-Western State Medical University named after I.I. Mechnikov, Saint Petersburg, Russia.

Introduction: patients with urinary stone disease during consultation often cannot realize their condition and features of upcoming procedure. Creation of 3D printed models is also not always available or too expensive.

Aim: to create a special program that allows for virtual intrarenal visualization of the collecting system and kidney stone on devices based on the Android operating system and evaluate its efficiency in counseling patients before the upcoming percutaneous nephrolithotomy (PCNL). Read More

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[Retrograde intrarenal surgery using a 1.94 m superpulsed thulium fiber laser].

Urologiia 2021 Mar(1):28-32

FGAOU VO I.M. Sechenov First Moscow State Medical University, Moscow, Russia.

Introduction: surgical treatment of urinary stone disease plays an important role in urological practice. Stone fragmentation can be performed using various lithotripters, from which Holmium fiber laser (Ho: YAG) has currently taken the main place. According to the current literature, a superpulsed thulium fiber laser with a wavelength of 1. Read More

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Flexible ureteroscopy using a 120-w holmium laser: The low-energy/high-frequency approach.

Arch Esp Urol 2021 Apr;74(3):343-349

ASO S. Croce e Carle Cuneo. Cuneo. Italy.

Objectives: With the spread of more powerful lasers and the advent of new technologies, endoscopic interventions for urolithiasis are continuously evolving. The aim of this study is to present our experience and technique regarding Low Energy (LE)/High Frequency (HF) lithotripsy by using a 120-W Holmium laser (Lumenis®). METHODS: We retrospectively analysed our prospectively maintained Retrograde Intra Renal Surgery (RIRS) database. Read More

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Modulation of Tubular pH by Acetazolamide in a Ca Transport Deficient Mice Facilitates Calcium Nephrolithiasis.

Int J Mol Sci 2021 Mar 17;22(6). Epub 2021 Mar 17.

Calcium Signaling Laboratory, Research Service, Veterans Affairs Medical Center, 50 Irving Street, NW, Washington, DC 20422, USA.

Proximal tubular (PT) acidosis, which alkalinizes the urinary filtrate, together with Ca supersaturation in PT can induce luminal calcium phosphate (CaP) crystal formation. While such CaP crystals are known to act as a nidus for CaP/calcium oxalate (CaOx) mixed stone formation, the regulation of PT luminal Ca concentration ([Ca]) under elevated pH and/or high [Ca] conditions are unknown. Since we found that transient receptor potential canonical 3 (TRPC3) knockout (KO; -/-) mice could produce mild hypercalciuria with CaP urine crystals, we alkalinized the tubular pH in TRPC3-/- mice by oral acetazolamide (0. Read More

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Risk of Metabolic Syndrome in Kidney Stone Formers: A Comparative Cohort Study with a Median Follow-Up of 19 Years.

J Clin Med 2021 Mar 2;10(5). Epub 2021 Mar 2.

Department of Urology, University Hospital Southampton, Southampton SO16 6YD, UK.

Background: Kidney stone formers (SF) are more likely to develop diabetes mellitus (DM), but there is no study examining risk of metabolic syndrome (MetS) in this population. We aimed to describe the risk of MetS in SF compared to non-SF.

Methods And Materials: SF referred to a tertiary referral metabolic centre in Southern England from 1990 to 2007, comparator patients were age, sex, and period (first stone) matched with 3:1 ratio from the same primary care database. Read More

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Association between renal urolithiasis after extracorporeal shock wave lithotripsy therapy and new-onset hypertension: an updated meta-analysis.

J Int Med Res 2021 Apr;49(4):3000605211002003

Department of Urology, Affiliated Hospital of Sichuan Medical College, Nanchong, China.

Objective: The long-term effect of extracorporeal shock wave lithotripsy (SWL) is still controversial. A previous meta-analysis showed no association between new-onset hypertension and entire upper urinary urolithiasis after SWL. Recently, there have been some reports on this topic. Read More

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Lumasiran, an RNAi Therapeutic for Primary Hyperoxaluria Type 1.

N Engl J Med 2021 04;384(13):1216-1226

From the Department of Pediatric Nephrology, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam (S.F.G., J.W.G.); the Division of Pediatric Nephrology, Shaare Zedek Medical Center, Jerusalem (Y.F.); the Department of Nephrology, Birmingham Women's and Children's Hospital, Birmingham (S.A.H.), and the Department of Paediatric Nephrology, Great Ormond Street Hospital (W.G.H.), and UCL Department of Renal Medicine, Royal Free Hospital (S.H.M.), London - both in the United Kingdom; Jacksonville Center for Clinical Research, Jacksonville, FL (M.J.K.); eStudySite, San Diego, CA (W.D.O.); Center for Rare Renal Diseases and INSERM Pediatric Clinical Investigation Center-Hospices Civils de Lyon and Université de Lyon, Lyon (P.C.), and the Department of Pediatric Nephrology, Hôpital Robert-Debré, Paris (G.D.) - both in France; the Pediatric Nephrology Unit, Galilee Medical Center, Nahariya (H.S.-L.), and the Pediatric Nephrology Institute, Rambam Health Care Campus, Haifa (D.M.) - both in Israel; the Icahn School of Medicine at Mount Sinai, New York (J.M.S., K.A.M.); the Department of Nephrology and Hypertension, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland (D.G.F.); the University of Bonn, Bonn, Germany (G.S.); Al Jalila Children's Hospital, Dubai, United Arab Emirates (E.S.); the Divisions of Pediatric Nephrology and Hypertension (D.J.S.) and Nephrology and Hypertension (J.C.L.), Mayo Clinic, Rochester, MN; and Alnylam Pharmaceuticals, Cambridge, MA (J.L., M.T.S., P.P.G., A.K.V., J.M.G., T.L.M.).

Background: Primary hyperoxaluria type 1 (PH1) is a rare genetic disease caused by hepatic overproduction of oxalate that leads to kidney stones, nephrocalcinosis, kidney failure, and systemic oxalosis. Lumasiran, an investigational RNA interference (RNAi) therapeutic agent, reduces hepatic oxalate production by targeting glycolate oxidase.

Methods: In this double-blind, phase 3 trial, we randomly assigned (in a 2:1 ratio) patients with PH1 who were 6 years of age or older to receive subcutaneous lumasiran or placebo for 6 months (with doses given at baseline and at months 1, 2, 3, and 6). Read More

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Risk factors of febrile urinary tract infections following retrograde intrarenal surgery for renal stones.

Medicine (Baltimore) 2021 Apr;100(13):e25182

Department of Urology, School of Medicine, Kyung Hee University.

Abstract: We aimed to evaluate the risk factors of febrile urinary tract infection (UTI) following retrograde intrarenal surgery (RIRS) for treating renal stones.We retrospectively reviewed the data of patients with 10 - 30 mm kidney stones who underwent RIRS from January 2014 to July 2017. Evaluation included age, gender, body mass index, stone size, stone location, and operative time. Read More

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A Rare, Unusual Presentation of Newberyite Urolithiasis in Adolescent Female -A Case Report and Review of Literature.

Urology 2021 Mar 21. Epub 2021 Mar 21.

Department of Urology, University of Alabama at Birmingham, Birmingham, AL.

We report a rare case of newberyite (magnesium monohydrate phosphate trihydrate) urolithiasis in a young female with a past medical history significant for longstanding autoimmune hepatitis. She presented to the emergency department with newly diagnosed nephrolithiasis. Over the next 2 years, she had recurrent renal calculi and 3 urologic procedures. Read More

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Recurrent Nephrolithiasis Causing Kidney Failure.

Am J Kidney Dis 2021 04;77(4):A18-A21

Division of Nephrology, Department of Medicine, Mount Sinai Hospital, New York, New York.

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Cystinuria poorly responding to treatment - the risk of chronic kidney disease.

Pol Merkur Lekarski 2021 Feb;49(289):60-63

Department of Internal Medicine, Nephrology and Dialysis, Military Institute of Medicine. Warsaw, Poland.

Cystinuria is the genetic condition for the increased excretion of cystine in the urine. Patients mainly suffer from afflictions related to the presence and passage of kidney stones. The currently available treatment methods include conservative treatment based on increased fluid intake, appropriate diet, medications and urological procedures. Read More

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February 2021

Risk of Nephrolithiasis and Nephrocalcinosis in Patients with Chronic Hypoparathyroidism: A Retrospective Cohort Study.

Adv Ther 2021 04 11;38(4):1946-1957. Epub 2021 Mar 11.

Aarhus University and Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark.

Introduction: Chronic hypoparathyroidism managed with conventional treatment, comprising oral administration of calcium and active vitamin D, has been associated with renal complications, including nephrolithiasis and nephrocalcinosis. Further larger-scale studies are needed to examine these risks. This study evaluated the risk of nephrolithiasis and nephrocalcinosis in patients with chronic hypoparathyroidism. Read More

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Flexible Ureteroscopy as the New Standard for the Management of Renal Transplant Urolithiasis <15 mm: A Single-Center Experience.

J Endourol 2021 Apr 26. Epub 2021 Apr 26.

Department of Urology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.

To determine the safety and efficacy of flexible ureteroscopy in the treatment of transplant urolithiasis. We reviewed a single-center series of 2652 patients who underwent surgical treatment for nephrolithiasis at our institution from 2009 to the present day to identify all patients undergoing ureteroscopy for treatment of transplant lithiasis. We identified 18 patients who underwent ureteroscopy for treatment of urolithiasis within the transplanted kidney or ureter. Read More

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Urolithiasis and sleeve gastrectomy: a prospective assessment of urinary biochemical variables.

Rev Col Bras Cir 2021 24;48:e20202804. Epub 2021 Feb 24.

- Hospital das Clínicas da Universidade Federal de Pernambuco (HC/UFPE), Department of General Surgery - Recife - PE - Brasil.

Introduction: to evaluate urinary biochemical alterations related to urolithogenesis processes after sleeve gastrectomy (SG).

Materials And Methods: : prospective study with 32 individuals without previous diagnosis of urolithiasis who underwent SG. A 24-h urine test was collected seven days prior to surgery and at 6-month follow-up. Read More

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Comparison of retrograde intrarenal surgery and percutaneous nephrolithotomy in multiple calyceal stones: A match pair analysis of 190 cases.

Arch Esp Urol 2021 Mar;74(2):247-253

Department of Urology. Karabuk University School of Medicine. Karabuk. Turkey.

Objectives: The current nephrolithia-sis guidelines have no recommendation about multiple calyceal stones treatment. We aimed to compare the results of two effective methods of RIRS and PNL operations in the treatment of multicalyx stones.

Methods: Data of patients who underwent RIRS or PNL for multicalyx stones between September 2014 and May 2019 in our clinic were evaluated retrospectively. Read More

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Does extracorporeal shock wave lithotripsy before retrograde intrarenal surgery complicates the surgery for upper ureter stone? The results of the RIRSearch group.

Int J Clin Pract 2021 May 2;75(5):e14115. Epub 2021 Mar 2.

Department of Urology, Gayrettepe Florence Nightingale Hospital, Istanbul, Turkey.

Aims: To evaluate the effect of pre-RIRS ESWL on the efficiency and safety of RIRS in the treatment of proximal ureter stones.

Methods: The patients in the study population were divided into two groups. Group-1 was composed of patients who had undergone ESWL for proximal ureter stones before RIRS and Group-2 was composed of patients who directly underwent RIRS without any prior ESWL. Read More

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[Saints and urology : The right saint for every disease].

Urologe A 2021 Mar 23;60(3):361-367. Epub 2021 Feb 23.

Institut für Geschichte, Philosophie und Ethik der Medizin, Centre for Health and Society, Heinrich-Heine-Universität, Düsseldorf, Deutschland.

During Medieval and Renaissance times up to the 19th century hagiotherapy was a common part of many different health offerings in society. Within the field of urology, kidney stone disease and venereal (sexually transmitted) diseases were the favourite subjects. Even today, the names of St. Read More

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Emergency department and hospital revisits after ambulatory surgery for kidney stones: an analysis of the Healthcare Cost and Utilization Project.

Urolithiasis 2021 Feb 17. Epub 2021 Feb 17.

Division of Urology, Hospital of the University of Pennsylvania, Perelman School of Medicine, University of Pennsylvania, 3 West Perelman Center for Advanced Medicine, 3400 Civic Center Boulevard, Philadelphia, PA, USA.

Our objective was to identify the rate of revisit to either emergency department (ED) or inpatient (IP) following surgical stone removal in the ambulatory setting, and to identify factors predictive of such revisits. To this end, the AHRQ HCUP ambulatory, IP, and ED databases for NY and FL from 2010 to 2014 were linked. Cases were selected by primary CPT for shock-wave lithotripsy (SWL), ureteroscopy (URS), and percutaneous nephrolithotomy (PNL) with accompanying ICD-9 for nephrolithiasis. Read More

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February 2021

Types of Renal Stones and its Variation with Age and Gender in a University Hospital of Nepal.

Kathmandu Univ Med J (KUMJ) 2020 Apr-Jun;18(70):193-196

Department of Surgery, Dhulikhel Hospital, Kathmandu University Hospital, Kathmandu University School of Medical Sciences, Dhulikhel, Kavre, Nepal.

Background Types of renal stones have profoundly changed in the last half-century, parallel to the change in lifestyle and dietary habit, with an increase of calcium stones. Among many lithogenic factors age and gender are considered to be associated with the types of renal stones. Studies evaluating the influence of age and gender on the distribution of the types of urinary calculi are scarce in Nepal. Read More

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February 2021

Stone Localization Is Pivotal for the Success of Percutaneous Nephrolithotomy.

Urol Int 2021 Feb 15:1-7. Epub 2021 Feb 15.

University Hospital for Urology, Klinikum Oldenburg, School of Medicine and Health Sciences, Carl von Ossietzky University Oldenburg, Oldenburg, Germany.

Objective: The objective of this study was to predict computed tomography (CT)-controlled treatment success after minimally invasive percutaneous nephrolithotomy (Mini-PCNL).

Patients And Methods: We relied on retrospective single institutional data from 92 kidney stone patients treated with Mini-PCNL. Residual stones after treatment were evaluated by post-Mini-PCNL CT scans. Read More

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February 2021

Exploring mechanisms of protein influence on calcium oxalate kidney stone formation.

Urolithiasis 2021 Feb 15. Epub 2021 Feb 15.

Division of Nephrology, Department of Medicine, Medical College of Wisconsin, 9200 W Wisconsin Avenue, Milwaukee, WI, 53295, USA.

Calcium oxalate monohydrate (COM) crystals are the primary constituent of most kidney stones, but urine proteins in stone matrix are believed to be critical elements for stone formation from these crystals. Recent data have shown that hundreds of proteins appear in the stone matrix with no explanation for inclusion of so many proteins. We have proposed a stone formation model with protein stimulated COM aggregation based on polyanion-polycation aggregation, which is supported by finding that matrix is highly enriched in strongly anionic and strongly cationic proteins. Read More

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February 2021