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Zhonghua Yi Xue Za Zhi 2019 Feb;99(6):447-452

Department of Cardiovascular Surgery, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China.

To evaluate the changes of rat renal function and cardiac function after transabdominal subtotal nephrectomy (STNx) and provide an ideal animal model for the study of chronic kidney disease (CKD) and cardiorenal syndrome (CRS). The SD rats (male, 5-6 weeks) were randomly divided into Sham group (10) and STNx group (10). The rats from Sham group underwent sham surgery, and the right nephrectomy plus the 2/3 left kidney artery ligation through abdominal incision were performed in the rats from STNx group. Read More

3D Print Med 2019 Feb 19;5(1). Epub 2019 Feb 19.

Center for Advanced Imaging Innovation and Research (CAI2R) and Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, NYU Langone Health, NYU School of Medicine, 660 First Avenue, Fourth Floor, New York, NY, 10016, USA.

Background: Patient-specific 3D models are being used increasingly in medicine for many applications including surgical planning, procedure rehearsal, trainee education, and patient education. To date, experiences on the use of 3D models to facilitate patient understanding of their disease and surgical plan are limited. The purpose of this study was to investigate in the context of renal and prostate cancer the impact of using 3D printed and augmented reality models for patient education. Read More

J Minim Access Surg 2019 Feb 18. Epub 2019 Feb 18.

Department of Urology, All India Institute of Medical Sciences, New Delhi, India.

Background: Nephron-sparing surgery (NSS) is the standard of care for small renal masses whenever feasible. This study aims to evaluate the perioperative outcomes of NSS performed by open (open partial nephrectomy [OPN]) or laparoscopic (laparoscopic PN [LPN]) or robotic (robotic PN [RPN]) approach over the past 6 years and to study the correlation of histopathological grade of renal cell carcinoma with the RENAL score.

Materials And Methods: A retrospective analysis of prospectively collected data of all patients who underwent NSS was done. Read More

Eur Urol Focus 2019 Feb 15. Epub 2019 Feb 15.

Division of Urology, University of Colorado Anschutz Medical Center, Aurora, CO, USA.

For most patients with an anatomically straightforward cT1a renal mass, the decreased risk of CKD would likely outweigh the risk of transient perioperative morbidity. However, for patients who are old, comorbid, or frail, or for those with anatomically complex or high-risk tumors, these relative risks must be individualized to deliver personalized care. Read More

Exp Clin Transplant 2019 Jan;17(Suppl 1):145-147

From the Department of Urology and Kidney Transplantation, Shahid Labbafinejad Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Multifocal synchronous renal cell carcinoma in the functioning allograft is a rare disease; there is no consensus regarding its treatment, and few cases have been reported. In isolated masses, some authorities advocate graft nephrectomy, and some recommend partial nephrectomy. To our knowledge, we describe the first experience of nephron-sparing surgery in multifocal synchronous renal cell carcinoma in an allograft with its long-term outcome. Read More

Am J Transplant 2019 Feb 15. Epub 2019 Feb 15.

Department of Surgery, National Medical Research Center of Transplantology and Artificial Organs named after academician V.I. Shumakov, Moscow, Russian Federation.

With the presence of organ shortage, living donors remain important sources of grafts, especially for pediatric recipients. Laparoscopic nephrectomy has become the gold standard for living donors. Additionally, laparoscopic partial liver procurement in living donors has proven its safety and feasibility in the latest studies. Read More

Gan To Kagaku Ryoho 2019 Jan;46(1):166-168

Division of Gastrointestinal Surgery, Chiba Cancer Center.

We report a case of synchronous cancer of the kidney and ascending colon that was resected concurrently using roboticassisted partialnephrectomy and laparoscopic ileocecalresection. A man in his 70s was diagnosed as having renaland ascending colon cancers. Thus, simultaneous resection was planned. Read More

Cardiovasc Interv Ther 2019 Feb 13. Epub 2019 Feb 13.

Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan.

Severe aortic stenosis (AS) is considered as an independent risk factor for perioperative cardiac complications of non-cardiac surgery. Surgical aortic valve replacement should be considered before non-cardiac surgery in patients with symptomatic severe AS. However, recently, transcatheter aortic valve replacement (TAVR) has emerged as an alternative approach for selected AS patients. Read More

J Cancer Res Clin Oncol 2019 Feb 13. Epub 2019 Feb 13.

Department of Urology and Urological Science Institute, Severance Hospital, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea.

Purpose: This study aimed at investigating the prognostic value of Preoperative controlling nutritional status (CONUT) score in non-metastatic clear-cell renal cell carcinoma of ≤ 7 cm on preoperative imaging.

Methods: We retrospectively included 1046 among 1637 patients who underwent radical or partial nephrectomy for solid renal masses ≤ 7 cm (2005-2014) after excluding other pathology, conditions affecting CONUT score components, metastasis, regional lymphadenopathy, positive margin, and follow-up < 12 months. We defined high and low CONUT according to cut-off of (2). Read More

Urologiia 2018 Dec(6):95-100

FGAOU VO of I.M. Sechenov First Moscow State Medical University of Minzdrav of Russia, Moscow, Russia.

Aim: to carry out a comparative analysis of treatment results of patients with renal tumors who were undergone to nephron-sparing surgery, depending on the type of temporary and definite hemostasis.

Materials And Methods: a total of 163 laparoscopic partial nephrectomies were performed by single surgeon from January 2015 to July 2018. The comparative analysis of treatment results of patients with renal tumors based on following parameters: tumor stage, features of the tumor site, the duration of surgery, the amount of blood loss, complications rate and grade as well as functional and oncological outcomes, depending on the type of temporary and definite hemostasis, was conducted. Read More

Urologiia 2018 Dec(6):80-84

Department of Urology, 2 Urologic Clinic,3 Scientific Research Institute of Uronephrology and Reproductive Health, 4 Department of Pathology of FGAOU VO of I.M. Sechenov First Moscow State Medical University of Minzdrav of Russia, Moscow, Russia.

Aim: to evaluate the features pathologic results of organ-sparing interventions in patients aged up to 40 years and older and assess an influence of patient age on the recurrence-free survival in case of pathologically proven renal cell cancer.

Materials And Methods: A retrospective analysis of laparoscopic organ-sparing removal of kidney tumors in 314 patients performed from January 2012 to May 2017 was conducted. The mean patient age was 54. Read More

Kidney Cancer 2018 Mar 30;2(1):47-55. Epub 2018 Mar 30.

Department of Surgical Oncology, Division of Urologic Oncology, Fox Chase Cancer Center, Temple Health, Philadelphia, PA, USA.

Background: Statin use is widespread among the general population. Data suggest a potentially beneficial effect of statin therapy on renal function following surgery. The impact of statins on post-partial nephrectomy (PN) renal function is unknown. Read More

Urol Oncol 2019 Feb 5. Epub 2019 Feb 5.

Department of Urology, Medical University of Vienna, Vienna, Austria; Department of Urology, Weill Cornell Medical College, New York, NY; Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX; Karl Landsteiner Institute of Urology and Andrology, Vienna, Austria. Electronic address:

Aim: To investigate the association of perioperative blood transfusion (PBT) with oncologic outcomes in patients with renal cell carcinoma (RCC), we conducted a systematic review and meta-analysis of the literature to clarify the long-term oncologic effect of PBT in patients undergoing nephrectomy for RCC.

Materials And Methods: We searched the MEDLINE, Web of Science, Cochrane Library and Scopus on 15th April 2018 to identify studies that compared patients who received PBT undergoing radical or partial nephrectomy for RCC to patients who did not with the aim of evaluating its impact on overall mortality (OM), cancer-specific mortality (CSM) and disease recurrence using multivariable cox regression analysis.

Results: A total of 19,681 patients in 7 studies matched the selection criteria for the systematic review and meta-analysis. Read More

Medicine (Baltimore) 2019 Feb;98(6):e14229

Department of Neurology, Peking University First Hospital.

Rationale: Detection of aquaporin-4 (AQP4) antibody in cerebrospinal fluid (CSF) was not suggested for the diagnosis of neuromyelitis opica spectrum disorders (NMOSD). However, some patients with NMOSD have only AQP4 antibody positive in CSF but not in serum with unknown cause. Besides, it is rarely reported that NMOSD complicated with renal clear cell carcinoma. Read More

J Laparoendosc Adv Surg Tech A 2019 Feb 6. Epub 2019 Feb 6.

1 Department of Urology, University of Istanbul Cerrahpasa School of Medicine, Istanbul, Turkey.

Objective: To assess the effectiveness and safety of laparoscopic partial nephrectomy (LPN) in T1a and T1b renal tumors using "Trifecta" in partial nephrectomy and determine the predictive factors in respect to the criteria that constitute Trifecta.

Materials And Methods: We retrospectively analyzed the data harvested from the patients who underwent LPN for T1a or T1b tumors. Preoperative, perioperative, and postoperative outcomes were evaluated and analyzed. Read More

World J Pediatr 2019 Feb 5. Epub 2019 Feb 5.

King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.

Background: Congenital and infantile nephrotic syndrome (CNS and INS) are rare inherited defects in glomerular filtration involving a variety of gene mutations. This study aimed to analyze all genetic mutations associated with congenital and infantile nephrotic syndrome treated at our institution. We also discussed our different approach secondary to culture and resources. Read More

Sci Rep 2019 Feb 4;9(1):1160. Epub 2019 Feb 4.

Department of Urology, Sheba Medical Center, Tel Hashomer, Israel.

The association between perioperative blood transfusion (PBT) with adverse oncological outcomes have been previously reported in multiple malignancies including RCC. Nevertheless, the importance of transfusion timing is still unclear. The primary purpose of this study is to appraise whether the receipt of intraoperative blood transfusion (BT) differ from postoperative BT in regards to cancer outcomes in renal cell carcinoma (RCC) patients treated with nephrectomy. Read More

BMC Nephrol 2019 Feb 4;20(1):40. Epub 2019 Feb 4.

Department of Urology, Charité - University Hospital, Berlin, Germany.

Background: Nephron-sparing surgery (NSS) remains gold standard for the treatment of localised renal cell cancer (RCC), even in case of a normal contralateral kidney. Compared to radical nephrectomy, kidney failure and cardiovascular events are less frequent with NSS. However, the effects of different surgical approaches and of zero ischaemia on the postoperative reduction in renal function remain controversial. Read More

Cleft Palate Craniofac J 2019 Feb 3:1055665618824440. Epub 2019 Feb 3.

3 Division of Plastic Surgery, Children's Mercy Hospital, Kansas City, MO, USA.

There is currently no recognized connection between the occurrence of cleft lip and/or palate (CL/P) and Wilms tumor (WT). A retrospective review of cleft team records (2001-2015) revealed 3 cases of children, all male, with concomitant diagnoses of CL/P and WT treated at our institution. These patients presented as infants for care of their CL/P, all with additional congenital anomalies, developmental delays, and growth delays. Read More

J Robot Surg 2019 Feb 2. Epub 2019 Feb 2.

Department of Urology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-Ku, Hamamatsu, 431-3192, Japan.

The objective of this study was to evaluate the impact of the early unclamping (EU) technique on perioperative outcomes in patients who underwent robot-assisted partial nephrectomy (RAPN). This study included 96 patients with small renal masses who underwent RAPN performed by a single surgeon using the da Vinci Xi between April 2016 and September 2018. EU and conventional clamping (CC) procedures were defined as those removing the renal artery clamp before and after renorrhaphy, respectively. Read More

Urol Int 2019 Feb 1:1-7. Epub 2019 Feb 1.

Department of Urology, The Second Affiliated Hospital of Anhui Medical University, Hefei,

Objective: To evaluate the efficacy and safety of early unclamping laparoscopic partial nephrectomy (LPN) for complex renal tumor relative to the standard artery clamping technique (SCT).

Methods: Sixty-one patients with complex renal tumor (RENAL score ≥7) underwent LPN at our institution from January 2013 to April 2017. LPN was performed via SCT in 32 patients and via the early unclamping technique (EUT) in 29 patients. Read More

World J Urol 2019 Feb 1. Epub 2019 Feb 1.

Department of Urology, University of California San Diego School of Medicine, La Jolla, CA, USA.

Purpose: To compare renal function and survival outcomes in patients with baseline chronic kidney disease (CKD) stage 2 undergoing partial (PN) or radical nephrectomy (RN), as nephron-sparing surgery is considered to be elective in this group.

Methods: Retrospective analysis of patients with CKD stage 2 and T1/T2 renal mass undergoing PN or RN from 2001 to 2015. Patients were stratified into substage CKD 2a or CKD 2b and analyzed between types of surgery. Read More

Urol Oncol 2019 Jan 28. Epub 2019 Jan 28.

Department of Urology, The First Affiliated Hospital of Nanchang University, Nanchang City, Jiangxi Province, China. Electronic address:

We conducted a meta-analysis to evaluate the efficiency and safety of partial nephrectomy (PN) compared with radical nephrectomy (RN) for large (≥7 cm) renal tumors. A comprehensive literature search with no restrictions on language or region was conducted from August up to October in 2018 in the electronic databases of PubMed, EMBASE, the Cochrane Library, and Scopus. Studies meeting the inclusion criteria were subjected to a systematic review and cumulative meta-analysis to assess the oncological, functional, and perioperative outcomes of PN compared with RN for large renal tumors. Read More

J Urol 2019 Jan 25. Epub 2019 Jan 25.

Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH.

Objectives: Retrospective studies suggest that partial nephrectomy (PN) provides improved survival compared to radical nephrectomy (RN), even when performed electively. However, selection-bias may be contributing. We evaluate factors associated with non-renal cancer-related mortality (NRCM) after PN/RN for patients with preoperative GFR≥60ml/min/1. Read More

Urol Oncol 2019 Jan 25. Epub 2019 Jan 25.

Glickman Urological and Kidney Institute, Department of Urology, Cleveland Clinic, Cleveland, OH. Electronic address:

Objective: To compare perioperative, oncological and functional outcomes of robotic partial nephrectomy (RPN) versus cryoablation in elderly patients (>75 years old), accounting for patient's and tumor's related factors.

Methods: Retrospective institutional review of 312 consecutive elderly patients (> 75 years old) who underwent RPN or cryoablation for renal mass (June 2006-December 2016). Demographic, perioperative, functional, and oncological data were evaluated. Read More

Asian J Surg 2019 Mar 26;42(3):507-513. Epub 2019 Jan 26.

Ministry of Health, Diskapi Yildirim Beyazid Education and Research Hospital, Department of Urology, Ankara, Turkey.

Objective: It is aimed to define the existence of pseudocapsular structure on renal tumours, illuminate the relation between pseudocapsular invasion and Fuhrman grade histological type that are among histopathologic prognostic risk factors and determine the relation between surgical margin positivity and existence of pseudocapsular invasion. Sequential partial nephrectomy series and relevant pathological preparations were retrospectively reviewed in order to evaluate these issues.

Methods: The study includes 123 patients diagnosed with T1 renal tumour and treated with partial nephrectomy in between January 2007 and June 2016. Read More

J Clin Anesth 2019 Jan 25;56:55-56. Epub 2019 Jan 25.

Anesthesia and Intensive Care Unit, Azienda Romagna, M. Bufalini Hospital, Viale Ghirotti 286, 47521 Cesena, Italy. Electronic address:

Cancer Biomark 2019 Jan 15. Epub 2019 Jan 15.

Department of Urology, Peking University Shenzhen Hospital, Shenzhen, Guangdong 518036, China.

Objective: Renal cell carcinoma (RCC) is one of the most common genitourinary cancers, and advanced RCC usually leads to poor prognosis. Therefore, identifying novel biomarkers for predicting the progression and prognosis of RCC is essential. The present study aims to evaluate the clinical value of miR-183-5p in RCC development and prognosis after surgery. Read More

Asian J Endosc Surg 2019 Jan 28. Epub 2019 Jan 28.

Department of Urology, Hamamatsu University School of Medicine, Hamamatsu, Japan.

Introduction: The objective of this study was to evaluate the initial learning curve for robot-assisted partial nephrectomy (RAPN) using the da Vinci Xi Surgical System (Intuitive Surgical, Sunnyvale, California).

Methods: This study included the initial 65 consecutive patients with small renal tumors who had undergone RAPN at our institution. A single trained surgeon with extensive experience in robot-assisted radical prostatectomy, but not in laparoscopic partial nephrectomy, performed RAPN for all patients using the da Vinci Xi. Read More

Curr Urol Rep 2019 Jan 26;20(1). Epub 2019 Jan 26.

Department of Nephrology, University of Oklahoma, Tulsa, OK, USA.

Purpose Of Review: Few procedures involve the ischemia-reperfusion injury to organs purposely. Two clear examples in urologic surgery consist on kidney transplantation and partial nephrectomies.

Recent Findings: Mannitol is an osmotic diuretic that is commonly used in partial nephrectomies and kidney transplantation to increase renal blood flow and decrease warm-ischemia-related renal injury to preserve estimated glomerular filtration rate (eGFR). Read More

Eur Urol 2019 Jan 22. Epub 2019 Jan 22.

Department of Urology, Franciscus Gasthuis en Vlietland, Rotterdam, The Netherlands.

Int J Comput Assist Radiol Surg 2019 Jan 24. Epub 2019 Jan 24.

Specialist Centre for Kidney Cancer, Department of Urology, The Royal Free London NHS Foundation Trust, London, UK.

Purpose: To determine whether the interactive visualisation of patient-specific virtual 3D models of the renal anatomy influences the pre-operative decision-making process of urological surgeons for complex renal cancer operations.

Methods: Five historic renal cancer patient pre-operative computed tomography (CT) datasets were retrospectively selected based on RENAL nephrectomy score and variety of anatomy. Interactive virtual 3D models were generated for each dataset using image segmentation software and were made available for online visualisation and manipulation. Read More

Cent European J Urol 2018 23;71(4):386-390. Epub 2018 Oct 23.

Centro Urológico Profesor Bengió, Córdoba, Argentina.

Introduction: The aim of this study was to describe the prognostic impact of microvascular invasion (MVI) in patients with non-metastatic renal cell cancer.

Material And Methods: We carried out a retrospective, descriptive and analytical study of patients with non-metastatic renal cell carcinoma who had undergone a radical or partial nephrectomy. Patients were divided according to the presence of MVI. Read More

Sci Rep 2019 Jan 24;9(1):760. Epub 2019 Jan 24.

Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, South Korea.

We sought to investigate the association between intraoperative urine output and postoperative acute kidney injury (AKI) in patients undergoing radical and partial nephrectomy. We retrospectively reviewed data of 742 patients. Postoperative AKI was defined by the Kidney Disease: Improving Global Outcomes criteria. Read More

J Robot Surg 2019 Jan 23. Epub 2019 Jan 23.

Department of Urology, San Raffaele Turro Hospital, San Raffaele University, Milan Via Stamira d'Ancona, 20, 20127, Milano, Italy.

The reports on the performance of robotic surgery in patients with dwarfism are anecdotal; anesthesiological issues and a challenging anatomy are the main factors that lead most of surgeons to prefer a more traditional approach. We present a case of bilateral robotic partial nephrectomy in a patient affected by achondroplastic dwarfism and aim to evaluate risks and issues in this type of surgery. Read More

Case Rep Urol 2018 20;2018:4325762. Epub 2018 Dec 20.

Department of Urology, Korgialenio-Benakio Hellenic Red Cross Hospital, Athanasaki 1, 11526 Athens, Greece.

Sporadic, synchronous, bilateral, or unilateral Renal Cell Carcinomas constitute a rare clinical entity. We report the case of a 68-year-old male patient who presented in our department due to incidentally discovered multiple, bilateral renal tumors. Magnetic Resonance Imaging demonstrated cT1b renal tumors at the lower pole of each kidney and a cT1a renal tumor at the upper pole of the right kidney. Read More

Ther Adv Urol 2019 Jan-Dec;11:1756287218815819. Epub 2019 Jan 8.

VCU Health and Division of Urology, Department of Surgery, McGuire VA Medical Center, 1200 East Broad St, Richmond, VA 23249, USA.

Over the past few years, the role of robotic-assisted partial nephrectomy (RPN) has exponentially grown. Multiple recognized factors contribute to postoperative renal function in patients undergoing RPN. The aim of this review is to identify these potential factors, and to evaluate strategies that may help optimize the goal of renal function preservation. Read More

Int J Urol 2019 Jan 22. Epub 2019 Jan 22.

Department of Urology, Peking University First Hospital, Institute of Urology, National Urological Cancer Center, Peking University, Beijing, China.

Objective: To present a DDD scoring system in assessing the complexity and outcomes of retroperitoneoscopic nephron-sparing surgery for kidney tumor.

Methods: We retrospectively evaluated 232 patients who underwent retroperitoneoscopic nephron-sparing surgery between January 2013 and September 2017 for a renal tumor. Both the DDD score and RENAL score were used to classify the tumors. Read More

Turk J Urol 2019 Jan 1;45(1):17-21. Epub 2019 Jan 1.

Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio, USA.

Objective: To identify preoperative factors that predict positive surgical margins in partial nephrectomy.

Material And Methods: Using our institutional partial nephrectomy database, we investigated the patients who underwent partial nephrectomy for malignant tumors between January 2011 and December 2015. Patient, tumor, surgeon characteristics were compared by surgical margin status. Read More

Nihon Hinyokika Gakkai Zasshi 2018 ;109(1):7-13

The Department of Urology, Ehime Prefectural Central Hospital.

(Objectives) Recently, partial nephrectomy has been recommended for patients with T1 renal cell carcinoma to preserve renal function. In this study, we retrospectively investigated the factors that affect renal function after laparoscopic or robotic partial nephrectomy using cold or warm ischemia. (Patients and methods) We reviewed 105 patients who underwent laparoscopic or robotic partial nephrectomy between March 2006 and July 2016. Read More

Urology 2019 Jan 16. Epub 2019 Jan 16.

Division of Urologic Surgery, Washington University School of Medicine, St. Louis, MO.

Objective: To determine whether performing robot-assisted partial nephrectomy without warm ischemia "off-clamp" results in favorable postoperative renal functional outcomes compared with the on-clamp method.

Methods: We conducted a prospective trial of 80 patients who underwent robot-assisted partial nephrectomy. They were randomized in a 1:1 ratio to undergo the procedure with renal artery clamping or without clamping. Read More

Int J Urol 2019 Jan 18. Epub 2019 Jan 18.

Department of Urology, Graduate School of Biomedical and Health Science, Hiroshima University, Hiroshima, Japan.

Eur Urol 2019 Jan 14. Epub 2019 Jan 14.

Department of Surgical Oncology/Division of Urology and Urologic Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA.

Recent work by Gershman and colleagues adds to collective data favoring partial nephrectomy to optimize functional preservation while maintaining oncological equipoise in the management of T1 renal cancer, and should not be over-interpreted as an endorsement to preferentially perform radical nephrectomy. Read More

BJU Int 2019 Jan 17. Epub 2019 Jan 17.

Unit of Oncologic Minimally-Invasive Urology and Andrology, Department of Urology, Careggi Hospital, University of Florence, Florence, Italy.

Objective: To identify meaningful predictors and to develop a nomogram of postoperative surgical complications in patients treated with partial nephrectomy (PN).

Patients And Methods: We prospectively evaluated 4308 consecutive patients who had surgical treatment for renal tumours, between 2013 and 2016, at 26 Italian urological centres (RECORd 2 project). A multivariable logistic regression for surgical complications was performed. Read More

Medicine (Baltimore) 2019 Jan;98(3):e13872

Department of Obstetrics and Gynecology, People's Hospital of Zhengzhou University.

Rationale: Intrauterine device (IUD) is commonly used in China. Its complications include uterine perforation, IUD ectopic migration, etc. However, a migrated IUD rarely leads to renal failure. Read More

Int J Urol 2019 Jan 16. Epub 2019 Jan 16.

Department of Urology, Tokyo Women's Medical University, Tokyo, Japan.

Objective: To investigate peritumoral pseudocapsule status in patients with renal cell carcinoma who underwent robot-assisted laparoscopic partial nephrectomy, and to examine predictive factors associated with the absence of peritumoral pseudocapsule.

Methods: A total of 367 patients with clinical T1 renal cell carcinoma who underwent robot-assisted laparoscopic partial nephrectomy were divided into two groups according to peritumoral pseudocapsule status. The groups were compared in terms of patient and tumor characteristics. Read More

Curr Urol Rep 2019 Jan 16;20(1). Epub 2019 Jan 16.

Department of Urology, La Fe Hospital, Fernando Abril Martorell 106, 46026, Valencia, Spain.

Purpose Of Review: An endophytic renal tumor represents a special surgical challenge in terms of location and safe removal. For this reason we wanted to review the existing literature on this subject.

Recent Findings: In high-activity robotic centers, robot-assisted partial nephrectomy (RAPN) is a safe and efficacious surgical approach for completely endophytic renal tumors. Read More

Radiology 2019 Mar 15;290(3):732-743. Epub 2019 Jan 15.

From the Departments of Radiology (S.K.K.), Population Health (S.K.K., R.S.B.), Urology (W.C.H.), and Medicine (R.S.B.), NYU School of Medicine, 550 First Ave, New York, NY 10016; Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY (E.B.E.); and Institute for Technology Assessment and Department of Radiology, Massachusetts General Hospital, Boston, Mass (P.V.P.).

Purpose To compare the effectiveness of personalized treatment for small (≤4 cm) renal tumors versus routine partial nephrectomy (PN), accounting for various competing causes of mortality. Materials and Methods A state-transition microsimulation model was constructed to compare life expectancy of management strategies for small renal tumors by using 1 000 000 simulations in the following ways: routine PN or personalized treatment involving percutaneous ablation for risk factors for worsening chronic kidney disease (CKD), and otherwise PN; biopsy, with triage of renal cell carcinoma (RCC) to PN or ablation depending on risk factors for worsening CKD; active surveillance for growth; and active surveillance when MRI findings are indicative of papillary RCC. Transition probabilities were incorporated from the literature. Read More

Investig Clin Urol 2019 Jan 23;60(1):14-20. Epub 2018 Nov 23.

Department of Urology, Ajou University Hospital, Ajou University School of Medicine, Suwon, Korea.

Purpose: To evaluate the significance of preoperative and follow-up neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) as prognostic factors for recurrence in patients with non-metastatic clear cell renal cell carcinoma (NMCCRCC).

Materials And Methods: We retrospectively reviewed the medical records of 309 patients with NMCCRCC who underwent radical or partial nephrectomy. The prognostic significance of various clinicopathological variables, preoperative NLR (pNLR) and PLR (pPLR), and NLR and PLR at recurrence or quasi-recurrence (rNLR and rPLR) for recurrence-free survival (RFS) was analyzed. Read More

Medicine (Baltimore) 2019 Jan;98(2):e13927

Department of Urology, The Third Central Hospital of Tianjin, Tianjin Key Laboratory of Artificial Cell.

Laparoscopic nephron-sparing partial nephrectomy with segmental renal artery blocking (SRPN) has been widely used in the treatment of localized renal tumors. However, the impact of ischemia-reperfusion injury (IRI) during SRPN remains controversial. This study aims to evaluate the correlation between affected renal function and affected renal volume after SRPN for localized renal tumor treatment, explore the effect of IRI on renal function after SRPN. Read More