Hydroxychloroquine for the prevention of fetal growth restriction and prematurity in lupus pregnancy: a systematic review and meta-analysis.
- Guillotin Vivien,
- Bouhet Alice,
- Barnetche Thomas,
- Richez Christophe,
- Truchetet Marie-Elise,
- Seneschal Julien,
- Duffau Pierre,
- Lazaro Estibaliz,
Joint Bone Spine 2018 Apr 6. Epub 2018 Apr 6.
Division of internal Medicine and Infectious Diseases, Haut-Lévêque Hospital, Pessac, France. Electronic address:
Objectives: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that primarily affects women of childbearing age. While the impact of hydroxychloroquine (HCQ) on SLE activity and neonatal lupus occurrence has been evaluated in several studies, its role on prematurity and intrauterine growth restriction (IUGR) remains uncertain. To assess the impact of HCQ exposure on prematurity and IUGR during pregnancy in women with SLE. Read More