8,612 results match your criteria Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia[Journal]
Arq Gastroenterol 2018 Jul-Sep;55(3):314-320
Hospital Português, Unidade de Gastroenterologia e Hepatologia, Salvador, BA, Brasil.
Acute kidney injury is a common complication of cirrhosis, occurring in up to 20% of patients hospitalized with cirrhosis. This field is rapidly changing, with significant advances in classification, biomarkers and therapy over the last few years. On the behalf of the Brazilian Society of Hepatology, a panel of experts in Hepatology and Nephrology reviewed published evidence to integrate findings and develop the recommendations presented in this manuscript. Read More
Braz J Med Biol Res 2018 Dec 10;52(1):e7974. Epub 2018 Dec 10.
Section of Nephrology, Yale University School of Medicine, New Haven, CT, USA.
Details about the acid-base changes in hemodialysis are scarce in the literature but are potentially relevant to adequate management of patients. We addressed the acid-base kinetics during hemodialysis and throughout the interdialytic period in a cross-sectional study of adults undergoing conventional hemodialysis. Samples for blood gas analysis were obtained from the arterial limb of the arteriovenous fistula before the first session of the week (HD1), immediately at the end of HD1, and on sequential collections at 15, 30, 45, 60, and 120 min post-HD1. Read More
J Nephrol 2018 Dec 10. Epub 2018 Dec 10.
Clinical and Research Laboratory on Urinary Sediment, U.O.C. di Nefrologia, Dialisi e Trapianto di Rene, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via della Commenda, 15, Milan, Italy.
Background: Isolated microscopic hematuria is a condition characterized by the presence in the urine of an "abnormal" number of erythrocytes in the absence of proteinuria. Several studies have been published on this condition, but with heterogeneous inclusion criteria and variable outcomes at follow-up. In this retrospective study, we describe a selected and homogenous cohort of patients who presented with isolated microscopic hematuria of glomerular origin. Read More
Nefrologia 2018 Dec 6. Epub 2018 Dec 6.
UGC de Nefrología, Hospital Universitario Reina Sofía, Córdoba; Instituto Maimónides de Investigación Biomedica de Córdoba (IMIBIC), Córdoba, España. Electronic address:
Nefrologia 2018 Dec 7. Epub 2018 Dec 7.
Servicio de Nefrología, Centro de Hemodiálisis AVERICUM SL Negrín, Las Palmas de Gran Canaria, Las Palmas, España.
Blood Purif 2018 Dec 6:1-7. Epub 2018 Dec 6.
Department of Nephrology, Dialysis and Transplant, San Bortolo Hospital, Vicenza, Italy.
Background: Sepsis is a life-threatening condition often associated with a high incidence of multiple organs injury. Several papers suggested the immune response by itself, with the production of humoral inflammatory mediators, is crucial in determining organ injury. However, little is known of how sepsis directly induces organ injury at the cellular levels. Read More
J Travel Med 2018 Dec 6. Epub 2018 Dec 6.
Centre for Tropical Diseases, IRCCS Sacro Cuore Don Calabria hospital, Via Sempreboni 5, 37024 Negrar, Verona, Italy.
Medicina (B Aires) 2018 ;78(6):440-442
Servicio de Oncología, Hospital Universitario Austral, Pilar, Buenos aires, Argentina.
The condition of immunosuppressed increases the risk of cancer in kidney transplant patients, as compared to the general population. The best survival of inmunosupressed patients in recent years has turned both neoplasms and cardiovascular diseases into the main causes of morbidity and mortality. We present the case of a renal transplanted patient who developed an unusual form of mesenchymal tumor such as the aggressive angiomyxoma, four years after the implant and requiring wide surgical resection. Read More
Nefrologia 2018 Nov 28. Epub 2018 Nov 28.
Servicio Nefrología, Hospital Torrecárdenas, Almería, Spain.
The Global Burden of Disease (GBD) study measures the health of populations worldwide and by country on an annual basis and aims at helping guide public policy on health issues. The GBD estimates for Spain in 2016 and recent trends in mortality and morbidity from 2006 to 2016 were recently published. According to these estimates, chronic kidney disease was the 8th cause of death in Spain in 2016. Read More
Med Clin (Barc) 2018 Nov 27. Epub 2018 Nov 27.
Servicio de Nefrología, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Hospital Universitario Ramón y Cajal, Madrid, España; Red de Investigación Renal (REDinREN), Madrid, España.
Introduction: The outcome and prognosis of systemic lupus erythematosus (SLE) in long-term kidney transplantation (KT) is variable. The objective of this study was to analyse the survival of the graft and the patient, comparing rates with a control group (primary glomerulonephritis [PGN]).
Materials And Methods: Forty-three patients receiving a KT with diagnosis of lupus nephritis (LN) and 367 patients with PGN were compared between January 1980 and December 2014. Read More
Rev Soc Bras Med Trop 2018 Nov-Dec;51(6):753-760
Disciplina de Doenças Infecciosas e Parasitárias, Faculdade de Medicina, Universidade Federal Fluminense, Niterói, RJ, Brasil.
Introduction: Dengue is one of the most important mosquito-borne infections. Severe cases are more frequently observed in adults. However, in 2008, the State of Rio de Janeiro, Brazil, experienced a severe dengue epidemic that primarily affected children and caused many cases of dengue hemorrhagic fever (DHF) and death. Read More
Dig Dis Sci 2018 Dec 3. Epub 2018 Dec 3.
Hepatology and Liver Transplant Unit, Facultad de Medicina, Hospital Universitario Austral, Universidad Austral, Av. Presidente Perón 1500, B1629HJ, Pilar, Buenos Aires, Argentina.
Background: Biannual ultrasound (US) is recommended as the clinical screening tool for hepatocellular carcinoma (HCC). The effectiveness of surveillance according to the place where US is performed has not been previously reported.
Aims: To compare the effectiveness of US performed in the center responsible for follow-up as opposed to US proceeding from centers other than that of follow-up. Read More
Endocrinol Diabetes Nutr 2018 Nov 30. Epub 2018 Nov 30.
Unidad de Nefrología, Fundación para la investigación del Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, España.
Introduction: Patients with chronic kidney disease (CKD) and diabetes mellitus (DM) have high cardiovascular risk. Both conditions are related to systemic atherosclerosis and vascular calcification. The prevalence and severity of coronary artery calcification (CaC) is higher in patients with DM, regardless of their renal function. Read More
Nefrologia 2018 Nov 30. Epub 2018 Nov 30.
Laboratorio Traslacional Cardiorrenal, Instituto de Investigación i+12, Hospital Universitario 12 de Octubre, Madrid, España; Unidad de Hipertensión, Servicio de Nefrología, Hospital Universitario 12 de Octubre, Madrid, España. Electronic address:
Background And Objective: Matrix metalloproteinases (MMPs) are involved in deleterious tissue remodeling associated with target organ damage in renal disease. The aim of this study was to study the association between renal dysfunction and activity of the inflammatory metalloproteinase MMP-9 in hypertensive patients with mild-moderate chronic kidney disease (CKD).
Material And Methods: Plasmatic active MMP-9, total MMP-9, tissue inhibitor of MMP-9 (TIMP-1), MMP-9/TIMP-1 ratio and MMP-9-TIMP-1 interaction were analyzed in 37 hypertensive patients distributed by estimated glomerular filtration rate (eGFR) in 3 groups:>90, 90-60 y 60-30mL/min/1. Read More
J Healthc Qual Res 2018 Nov - Dec;33(6):329-333. Epub 2018 Nov 27.
Servicio de Clínica Médica, Hospital Universitario Austral, Buenos Aires, Argentina.
Since January 2015 we have carried out a multiple-intervention strategic plan to reduce hospital stay in renal transplant recipients. The main objective of this study is to compare results of renal transplantation before and after putting into effect this plan in terms of graft and patient survival, readmissions and incidence of acute rejection during the first year post transplantation. In this retrospective analysis we included all patients 18 years of age or older who were transplanted at our institution. Read More
Nefrologia 2018 Nov 26. Epub 2018 Nov 26.
Hospital del Mar, Barcelona, España. Electronic address:
Introduction: Many European countries have transplant programmes with controlled donors after cardiac death (cDCD). Twenty-two centres are part of GEODAS group. We analysed clinical results from a nephrological perspective. Read More
Front Physiol 2018 13;9:1599. Epub 2018 Nov 13.
Departamento de Ciencias de la Salud, Universidad de Jaén, Jaén, Spain.
The aim of this study was to investigate if urinary glutamyl aminopeptidase (GluAp), alanyl aminopeptidase (AlaAp), Klotho and hydroxyproline can be considered as potential biomarkers of renal injury and fibrosis in an experimental model of obesity. Male Zucker lean (ZL) and obese (ZO) rats were studied from 2 to 8 months old. Kidneys from ZO rats at the end of the study (8 months old) developed mild focal and segmental glomerulosclerosis as well as moderate tubulointerstitial injury. Read More
Semergen 2018 Nov 24. Epub 2018 Nov 24.
Unidad de Gestión Clínica de Urología, HUCA, Oviedo, Asturias, España.
Quality of Life Related to Health is currently considered one of the primary therapeutic objectives in renal failure patients who need substitution treatment as life prolonging therapy. Sexual health is a basic right that positively affects the quality of life. Although a significant percentage of chronic patients have some type of sexual dysfunction, this is not openly discussed, making it important for doctors to address these issues in the clinic. Read More
Nefrologia 2018 Nov 22. Epub 2018 Nov 22.
Departamento de Anatomía Patológica, Hospital San Cecilio, Granada, España.
Nefrologia 2018 Nov - Dec;38(6):573-578. Epub 2018 Jul 7.
Servicio de Nefrología, Fundació Puigvert, IIB Sant Pau, RedinRen, Barcelona, España.
Nefrologia 2018 Nov 21. Epub 2018 Nov 21.
Enfermedades Renales Hereditarias, Servicio de Nefrología, Fundació Puigvert, Barcelona, España; Instituto de Investigaciones Biomédicas Sant Pau (IIB-Sant Pau), Barcelona, España; Universidad Autònoma de Barcelona, REDinREN, Instituto de Investigación Carlos III, Barcelona, España. Electronic address:
MYH9 related diseases are caused by mutations in the MYH9 gene and constitute a rare group of genetic entities. Its inheritance follows an autosomal dominant pattern. The MYH9 gene, encodes the nonmuscle myosin heavy chain IIA, expressed in different tissues and especially in podocytes and mesangial cells. Read More
Nefrologia 2018 Nov 21. Epub 2018 Nov 21.
Servicio de Nefrología, Hospital Vithas Perpetuo Socorro, Alicante, España.
Urolithiasis 2018 Nov 23. Epub 2018 Nov 23.
UOC Nefrologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Deciding whether to accept a donor with nephrolithiasis is a multifaceted task because of the challenge of finding enough suitable donors while at the same time ensuring the safety of both donors and recipients. Until not long ago, donors with a history of renal stones or with stones emerging during screening on imaging were not considered ideal, but recent guidelines have adopted less stringent criteria for potential donors at risk of stones. This review goes through the problems that need to be approached to arrive at a wise clinical decision, balancing the safety of donors and recipients with the need to expand the organ pool. Read More
Rev Port Cardiol 2018 Nov 20;37(11):935-945. Epub 2018 Nov 20.
Unidade de Insuficiência Cardíaca, Serviço de Medicina III, Hospital São Francisco Xavier, Lisbon, Portugal; NOVA Medical School, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal.
Heart failure is a disease with high direct and indirect costs. Current treatment includes drugs that alter disease progression and drugs that to improve symptoms. Loop diuretics are the cornerstone of congestion relief for acute management, as well as for chronic stabilization. Read More
Am J Kidney Dis 2018 Dec;72(6):774-775
Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Renal Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Nefrologia 2018 Nov 19. Epub 2018 Nov 19.
Servicio de Nefrología, Hospital Gregorio Marañón, Madrid, España.
Background And Objective: Online haemodiafiltration (OL-HDF) with high convective transport volumes improves patient survival in haemodialysis. Limiting the amount of convective volume has been proposed in patients with diabetes mellitus due to glucose load that is administered with replacement fluid. The objective of the study was to analyse the influence of substitution volume on the evolution of the metabolic profile and body composition of incident diabetic patients on OL-HDF. Read More
Kidney Int 2018 Dec;94(6):1069-1072
Division of Nephrology and Hypertension, Saint Louis University, Saint Louis, Missouri, USA.
J Bras Nefrol 2018 Nov 14. Epub 2018 Nov 14.
Universidade Federal de Minas Gerais, Faculdade de Medicina, Belo Horizonte, MG, Brasil.
J Bras Nefrol 2018 Nov 14. Epub 2018 Nov 14.
Universidade Federal de Minas Gerais, Hospital das Clínicas, Unidade de Nefrologia Pediátrica, Belo Horizonte, MG, Brasil.
Involvement of the kidneys by lupus nephritis (LN) is one of the most severe clinical manifestations seen in individuals with systemic lupus erythematosus (SLE). LN is more frequent and severe in pediatric patients and has been associated with higher morbidity and mortality rates. This narrative review aimed to describe the general aspects of LN and its particularities when affecting children and adolescents, while focusing on the disease's etiopathogenesis, clinical manifestations, renal tissue alterations, and treatment options. Read More
Nefrologia 2018 Nov 17. Epub 2018 Nov 17.
Servicio de Nefrología, Hospital Universitario Doce de Octubre, Madrid, España; Departamento de Medicina, Universidad Complutense, Madrid, España.
Introduction: Primary hyperparathyroidism (PHPT) is a common endocrine disorder characterised by hypercalcaemia and parathormone increase. Decreased glomerular filtration rate (<60ml/min) continues to be a parathyroidectomy (PTX) criterion in asymptomatic PHPT. The influence of PTX on renal function evolution is the subject of debate. Read More
Arch Argent Pediatr 2018 12;116(6):e757-e761
Nefrología, Hospital Universitario Virgen Macarena, Sevilla, España.
The finding of persistent hypercalcemia suggests doing other medical tests to find the cause. Familial hypocalciuric hypercalcemia is usually benign and it requires no treatment. It is important to do CASR gene sequencing to avoid unnecessary treatments. Read More
Lupus 2018 Nov 19:961203318812679. Epub 2018 Nov 19.
1 Grupo de Nefrología, Universidad Simón Bolívar, Barranquilla, Colombia.
Background: Systemic lupus erythematosus is a heterogeneous chronic inflammatory autoimmune disorder characterized by an exacerbated expression of cytokines and chemokines in different tissues and organs. Renal involvement is a significant contributor to the morbidity and mortality of systemic lupus erythematosus, and its diagnosis is based on renal biopsy, an invasive procedure with a high risk of complications. Therefore, the development of alternative, non-invasive diagnostic tests for kidney disease in patients with systemic lupus erythematosus is a priority. Read More
BMC Nephrol 2018 Nov 14;19(1):324. Epub 2018 Nov 14.
Servicio de Nefrología, Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Mexico.
Background: Acyclovir is one of the most common prescribed antiviral drugs. Acyclovir nephrotoxicity occurs in approximately 12-48% of cases. It can present in clinical practice as acute kidney injury (AKI), crystal-induced nephropathy, acute tubulointerstitial nephritis, and rarely, as tubular dysfunction. Read More
J Clin Hypertens (Greenwich) 2018 Nov 14. Epub 2018 Nov 14.
Departamento de Nefrología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
J Bras Nefrol 2018 Nov 8. Epub 2018 Nov 8.
Programa de Pós-Graduação em Medicina: Ciências Médicas, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.
Introduction: The development of novel non-invasive biomarkers of kidney graft dysfunction, especially in the course of the delayed graft function period would be an important step forward in the clinical practice of kidney transplantation.
Methods: We evaluated by RT-PCR the expression of miRNA-146 to -5p ribonucleic micro-acids (miRNAs) in the peripheral blood and renal tissue obtained from kidney transplant recipients who underwent a surveillance graft biopsy during the period of delayed graft function.
Results: In biopsy samples, the expression of miR-146a-5p was significantly increased in the group of patients with delayed graft function (DGF) (n = 33) versus stables patients (STA) (n = 13) and patients with acute rejection (AR) (n = 9) (p = 0. Read More
BMC Urol 2018 Nov 12;18(1):101. Epub 2018 Nov 12.
U.O.C. Nefrologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italia.
Background: Previous studies have shown that, compared with non-stone formers, stone formers have a higher papillary density measured with computer tomography (CT) scan. The effect of increased hydration on such papillary density in idiopathic calcium stone formers is not known.
Methods: Patients with recurrent calcium oxalate stones undergoing endourological procedures for renal stones at our Institution from June 2013 to June 2014 were considered eligible for enrolment. Read More
BMC Infect Dis 2018 Nov 12;18(1):554. Epub 2018 Nov 12.
Infectious Diseases Department, Centro Hospitalar de São João, Alameda Professor Hernâni Monteiro, 4200-319, Porto, Portugal.
Background: Cytomegalovirus (CMV) reactivation with neurological involvement in patients with acquired immunodeficiency syndrome (AIDS) is increasingly rare since the introduction of antiretroviral therapy (ART). Manifestations include encephalitis, myelitis, polyradiculopathy and, less commonly, mononeuritis multiplex (MNM). We report a case of disseminated CMV disease with gastrointestinal and peripheral and central nervous system involvement in a patient with AIDS, manifesting primarily as MNM. Read More
Am J Transplant 2018 Nov 12. Epub 2018 Nov 12.
Nephrology and Kidney Transplantation, Hospital Clinic de Barcelona, Barcelona, Catalunya, Spain.
J Vasc Access 2018 Nov;19(6):518-520
4 Nephrology and Dialysis Unit, Ospedale San Carlo Borromeo, Department of Clinical and Biomedical Sciences 'Luigi Sacco', University of Milan, Milan, Italy.
Pregnancy in dialysis patients is a rare but important event that challenges our knowledge and demands re-thinking many aspects of our practice, including vascular access. This editorial briefly discusses some open questions on vascular access in this situation that challenge the motto 'fistula first' and underline the need for personalised approaches. Information on vascular access in pregnant women is scant. Read More
Nefrologia 2018 Nov - Dec;38(6):579-586. Epub 2018 Nov 8.
Servicio de Nefrología y Trasplante Renal, Hospital Clínic, Barcelona, España. Electronic address:
Calciphylaxis, also known as calcific uraemic arteriolopathy, is a rare syndrome that typically causes skin necrosis and usually affects dialysis patients. Its pathogenesis is multifactorial and is the consequence of many factors causing ectopic calcifications in patients with chronic kidney disease, such as calcium-phosphate metabolism disorders, hyper- or hypo-parathyroidism, diabetes, obesity, systemic inflammation and the use of vitamin K antagonists, among others. From a clinical point of view, calciphylaxis may progress from painful purpura to extensive areas of skin necrosis that can potentially lead to superinfection and the death of the patient due to sepsis. Read More
Urolithiasis 2018 Nov 7. Epub 2018 Nov 7.
U.O.C. Nefrologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italia.
J Healthc Qual Res 2018 Sep - Oct;33(5):250-255. Epub 2018 Oct 5.
Hospital Universitario Ramón y Cajal, Madrid, España.
Introduction: Isolation precautions are an effective measure to prevent the spread of multi-resistant microorganisms (MMR). However, its implementation is complex and can increase some risks to the patient. The aim of this study is to determine whether the implementation of isolation precautions increase the risk of patient safety incidents (PSI) in critically ill patients. Read More
J Clin Med 2018 Nov 5;7(11). Epub 2018 Nov 5.
Department of Medicine, Division of Nephrology, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.
Pregnancy is possible in all phases of chronic kidney disease (CKD), but its management may be difficult and the outcomes are not the same as in the overall population. The prevalence of CKD in pregnancy is estimated at about 3%, as high as that of pre-eclampsia (PE), a better-acknowledged risk for adverse pregnancy outcomes. When CKD is known, pregnancy should be considered as high risk and followed accordingly; furthermore, since CKD is often asymptomatic, pregnant women should be screened for the presence of CKD, allowing better management of pregnancy, and timely treatment after pregnancy. Read More
Curr Rheumatol Rep 2018 Nov 5;20(12):80. Epub 2018 Nov 5.
Nephrology Unit, Parma University Hospital, Parma, Italy.
Purpose Of Review: We aim to review traditional concepts and recent developments on the nosology, pathophysiology, clinical phenotypes and treatment of chronic periaortitis (CP).
Recent Findings: CP is a rare disorder hallmarked by a periaortic fibro-inflammatory tissue. It can present as an isolated disease, but it can also be associated with other autoimmune and fibro-inflammatory lesions (e. Read More
Clin J Am Soc Nephrol 2018 Dec 5;13(12):1851-1858. Epub 2018 Nov 5.
Department of Nephrology, Hospital Universitario 12 de Octubre, Madrid, Spain.
Background And Objectives: Drug-induced acute interstitial nephritis represents an emerging cause of acute kidney disease, especially among polymedicated elderly patients. Although corticosteroids are frequently used, controversy exists about the timing of initiation, efficacy, safety, and duration of treatment.
Design, Setting, Participants, & Measurements: We performed a retrospective study of 182 patients with biopsy-proven drug-induced acute interstitial nephritis from 13 Spanish centers. Read More
Nefrologia 2018 Nov 2. Epub 2018 Nov 2.
Nephrology Department, Dialysis and Renal Transplant Center, "Dr. C.I. Parhon" University Hospital, "Grigore T. Popa" University of Medicine and Pharmacy, Iasi, Romania.
Background: Klotho is found in two forms: a transmembrane form and a soluble form (s-Klotho). In order to be excreted, s-Klotho, that is too large to be filtered, will probably reach the proximal convoluted tubule by a transcytosis process. The aim of our study was to show the relationship between the levels of s-Klotho and tubular injury in patients with diabetic kidney disease (DKD), using as tubular injury marker the kidney injury molecule-1 (KIM-1). Read More
Endocrinol Diabetes Nutr 2018 Nov 1. Epub 2018 Nov 1.
Servicio de Cirugía General y Aparato Digestivo, Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, España.
Background: Permanent hypoparathyroidism is the most common long-term complication after total thyroidectomy, causing significant morbidity and requiring long-term replacement therapy. Our study objective was to assess whether intact parathyroid hormone (iPTH) levels on the first day after total thyroidectomy are a good predictor of permanent hypoparathyroidism.
Patients And Methods: A retrospective observational study of all patients undergoing total thyroidectomy between January 2009 and December 2014. Read More
Nefrologia 2018 Oct 31. Epub 2018 Oct 31.
Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran Canaria, España.
Nefrologia 2018 Oct 31. Epub 2018 Oct 31.
Nova Medical School, Faculdade de Ciências Médicas - Universidade Nova de Lisboa, Lisbon, Portugal.
An Pediatr (Barc) 2018 Dec 30;89(6):386.e1-386.e9. Epub 2018 Oct 30.
Real Academia de Medicina de Cantabria, Santander, España.
The 50th Anniversary of Anales de Pediatría is a good time for the celebration of events and tributes, and also for critical thought. Anales de Pediatría is the official publication of scientific expression of the Spanish Association of Paediatrics (AEP). It has been published continuously since October 1968. Read More