Search our Database of Scientific Publications and Authors

I’m looking for a

    4178 results match your criteria Necrotizing Fasciitis

    1 OF 84

    Looking Beyond the Cell in Cellulitis.
    Adv Skin Wound Care 2017 May;30(5):209-212
    Vincent Maida, MD, MSc, BSc, CCFP(PC), FCFP, ABHPM, is Associate Professor, Division of Palliative Care, University of Toronto; and Clinical Assistant Professor, Division of Palliative Care, McMaster University and Division of Palliative Medicine, William Osler Health System, Toronto, Ontario, Canada. Joyce T. W. Cheung, MD, BSc, CCFP, is a Palliative Medicine Consultant, Division of Palliative Medicine, William Osler Health System, Toronto, Ontario, Canada.
    Background: Patients with erythematous skin are likely to receive a diagnosis of cellulitis; however, the accuracy of this diagnosis is approximately only 33%. The diagnosis of cellulitis should be made only after a thorough evaluation of all possible differential diagnoses. Cellulitis may be a primary process (superficial spreading infective process involving only the epidermis and dermis) versus a secondary (reactive) process incited by a subcutaneous process, such as an abscess, tenosynovitis, necrotizing fasciitis, and osteomyelitis. Read More

    Immunoglobulin G for patients with necrotising soft tissue infection (INSTINCT): a randomised, blinded, placebo-controlled trial.
    Intensive Care Med 2017 Apr 18. Epub 2017 Apr 18.
    Department of Intensive Care, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.
    Purpose: The aim of the INSTINCT trial was to assess the effect of intravenous polyspecific immunoglobulin G (IVIG) compared with placebo on self-reported physical function in intensive care unit (ICU) patients with necrotising soft tissue infection (NSTI).

    Methods: We randomised 100 patients with NSTI 1:1 to masked infusion of 25 g of IVIG (Privigen, CSL Behring) or an equal volume of 0.9% saline once daily for the first 3 days of ICU admission. Read More

    Management of necrotising fasciitis secondary to abdominal liposuction using a combination of surgery, hyperbaric oxygen and negative pressure wound therapy in a patient with burn scars.
    Int Wound J 2017 Apr 17. Epub 2017 Apr 17.
    Division of Plastic and Reconstructive Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
    Liposuction is the one of the most frequently performed cosmetic operations and usually has an easy recovery, with a reportedly low overall complication rate. Here, we report the case of a 60-year-old woman with type II diabetes mellitus and a previous burn injury of the abdomen who underwent abdominal liposuction and subsequently developed necrotising fasciitis. Following radical debridement, systemic antibiotic administration, negative pressure wound therapy and hyperbaric oxygen therapy, the wound healed completely. Read More

    A Rare Case of Tropical Pyomysitis Acquired on Vacation in a Healthy Male.
    J La State Med Soc 2017 Mar-Apr;169(2):53. Epub 2017 Apr 15.
    Department of Internal Medicine, Ochsner Medical Center, New Orleans, LA.
    Introduction: Pyomyositis has traditionally been considered a tropical disease. Increasing prevalence has been observed in more northern climates, especially with HIV, immunosuppression, and IV drug abuse as predisposing factors. Pyomyositis has the tendency to mimic other conditions, such as muscle contusion, necrotizing fasciitis, or septic arthritis. Read More

    A Rare Case of Raoultella planticola Pneumonia: An Emerging Pathogen.
    Respir Med Case Rep 2017 28;21:69-70. Epub 2017 Mar 28.
    University of Florida College of Medicine, Division of Pulmonology, Critical Care and Sleep Medicine, USA.
    Raoultella planticola (R. planticola), considered an environmental organism, is a gram negative, motile, bacillus with phenotypic similarities to the genus Klebsiella. The organism remains a rare cause of human infection with a few cases reported in the literature. Read More

    Skin diseases of the vulva: Infectious diseases.
    J Obstet Gynaecol 2017 Apr 11:1-9. Epub 2017 Apr 11.
    a Department of Dermatology , Bispebjerg Hospital , Copenhagen , Denmark.
    A multitude of infectious diseases of viral (genital herpes, herpes zoster, genital warts and molluscum contagiosum), bacterial (syphilis, chancroid, lymphogranuloma venereum, donovanosis, erysipelas, cellulitis and necrotising fasciitis, folliculitis, impetigo, bartholin gland abscess, trichomycosis and erythrasma), fungal (candidiasis and dermatophytosis) and parasitic (pediculosis pubis) origin may affect the vulvar area. Herein, we review the infections and their skin manifestations in the vulvar area. Read More

    Postsurgical Pyoderma Gangrenosum Versus Necrotizing Fasciitis: Can We Spot the Difference?
    Ann Plast Surg 2017 May;78(5):582-586
    From the Department of Plastic Surgery, Countess of Chester Hospital, Chester, PA.
    Background: Pyoderma gangrenosum is a rare noninfectious cutaneous disease characterized by expanding areas of skin ulceration around necrotic centers with purulent debris. Exceptionally, it can be precipitated by surgery alone, and this entity has been described as postsurgical pyoderma gangrenosum (PSPG). Cases of PSPG in the literature are rare. Read More

    Management and Novel Adjuncts of Necrotizing Soft Tissue Infections.
    Surg Infect (Larchmt) 2017 Apr 4;18(3):250-272. Epub 2017 Apr 4.
    Department of Surgery, University of Pittsburgh , Pittsburgh, Pennsylvania.
    Necrotizing soft tissue infections (NSTI) have been recognized for millennia and continue to impose considerable burden on both patient and society in terms of morbidity, death, and the allocation of resources. With improvements in the delivery of critical care, outcomes have improved, although disease-specific therapies are lacking. The basic principles of early diagnosis, of prompt and broad antimicrobial therapy, and of aggressive debridement have remained unchanged. Read More

    Air and its Sonographic Appearance: Understanding the Artifacts.
    J Emerg Med 2017 Mar 31. Epub 2017 Mar 31.
    Department of Emergency Medicine, Division of Emergency Ultrasound, Mount Sinai St. Luke's Hospital, Mount Sinai West Hospital, New York, New York.
    Background: Although air has traditionally been considered a barrier to sonographic imaging, when encountered in unusual settings it can serve as an important indicator of various pathologic states as well. Clinician recognition and thorough understanding of the characteristic pattern of artifacts generated by air are critical for making a number of important diagnoses.

    Case Series: We present five emergency department cases in which air was visualized in a pathologic location. Read More

    Radiologic Approach to Musculoskeletal Infections.
    Infect Dis Clin North Am 2017 Mar 30. Epub 2017 Mar 30.
    Section of Musculoskeletal Radiology, Imaging Institute, Cleveland Clinic, CCLCM/CWRU, 9500 Euclid Avenue, Cleveland, OH 44195, USA. Electronic address:
    Imaging is often used to establish a diagnosis of musculoskeletal infections and evaluate the full extent and severity of disease. Imaging should always start with radiographs, which provide an important anatomic overview. MRI is the test of choice in most musculoskeletal infections because of its superior soft tissue contrast resolution and high sensitivity for pathologic edema. Read More

    An Eye Popping Case of Orbital Necrotizing Fasciitis Treated with Antibiotics, Surgery, and Hyperbaric Oxygen Therapy.
    Am J Case Rep 2017 Apr 1;18:329-333. Epub 2017 Apr 1.
    Department of Internal Medicine, University of Cincinnati, Cincinnati, OH, USA.
    BACKGROUND Necrotizing fasciitis (NF) of the orbit is a rare and deadly condition that requires prompt surgical and medical management to decrease morbidity and mortality.  CASE REPORT Here we present an interesting case of an individual who developed fulminant NF of the left orbit requiring emergent surgical intervention, antibiotics, and subsequent hyperbaric oxygen therapy in an attempt to save the eye.  CONCLUSIONS With an early and aggressive multifaceted approach using antibiotics, surgery, and hyperbaric oxygen it may be possible to preserve eye structure and function. Read More

    Acute Chest Wall Infections: Surgical Site Infections, Necrotizing Soft Tissue Infections, and Sternoclavicular Joint Infection.
    Thorac Surg Clin 2017 May;27(2):73-86
    Section of General Thoracic Surgery, Division of Cardiothoracic Surgery, Department of Surgery, Oregon Health and Sciences University, 3181 SW Sam Jackson Park Road L353, Portland, OR 97239, USA.
    Acute chest wall infections are uncommon and share similar risk factors for infection at other surgical sites. Smoking cessation has been shown to decrease the risk of surgical site infection. Depending on the depth of infection and/or involvement of the organ space, adequate therapy involves antibiotics and drainage. Read More

    Immunization with a streptococcal multiple-epitope recombinant protein protects mice against invasive group A streptococcal infection.
    PLoS One 2017 29;12(3):e0174464. Epub 2017 Mar 29.
    Department of Biological Science and Technology, College of Medicine, I-Shou University, Kaohsiung, Taiwan.
    Streptococcus pyogenes (group A Streptococcus; GAS) causes clinical diseases, including pharyngitis, scarlet fever, impetigo, necrotizing fasciitis and streptococcal toxic shock syndrome. A number of group A streptococcus vaccine candidates have been developed, but only one 26-valent recombinant M protein vaccine has entered clinical trials. Differing from the design of a 26-valent recombinant M protein vaccine, we provide here a vaccination using the polyvalence epitope recombinant FSBM protein (rFSBM), which contains four different epitopes, including the fibronectin-binding repeats domain of streptococcal fibronectin binding protein Sfb1, the C-terminal immunogenic segment of streptolysin S, the C3-binding motif of streptococcal pyrogenic exotoxin B, and the C-terminal conserved segment of M protein. Read More

    Haemophilus influenzae Pyomyositis in a Patient with Diabetic Ketoacidosis: A Unique Case and Review of Literature.
    Case Rep Infect Dis 2017 2;2017:6307361. Epub 2017 Mar 2.
    Department of Infectious Disease, Einstein Medical Center, Philadelphia, PA, USA.
    Haemophilus influenzae is a Gram-negative bacillus commonly known to cause upper respiratory tract infections. Skin and soft tissue infections are very uncommon. Of these, the majority were associated with necrotizing fasciitis requiring emergent debridement. Read More

    Necrotising fasciitis after laparoscopic rectal cancer surgery.
    Ann R Coll Surg Engl 2017 Apr;99(4):e113-e114
    Mid Yorkshire Hospitals NHS Trust , UK.
    Necrotising fasciitis is a rare, serious infection of the deep fascia leading to subcutaneous tissue necrosis. It is extremely important for this condition to be identified and treated promptly as it bears significant mortality. We describe a case of necrotising fasciitis after laparoscopic rectal cancer surgery. Read More

    Cutaneous manifestations of disseminated gonococcemia.
    Dermatol Online J 2017 Jan 15;23(1). Epub 2017 Jan 15.
    Medical School, Louisiana State University Health Sciences Center, New Orleans.
    Background: Sexually transmitted infections, includingurogenital gonorrheal infection, are a growing healthconcern in the United States. Nearly 50% of cervicalinfections are asymptomatic. If left undiagnosedand untreated, there is a risk of disseminatedinfection. Read More

    Myelodysplastic syndrome diagnosed on the occasion of Fournier's gangrene.
    Rinsho Ketsueki 2017 ;58(2):113-118
    Hematology Division, JCHO Sapporo Hokushin Hospital.
    Fournier's gangrene (FG) is a fulminant infective necrotizing fasciitis, which includes the genital, perineal, and perianal regions. A 77-year-old man had previously been diagnosed as having diabetes mellitus (DM) and was treated with pioglitazone (15 mg) and miglitol (150 mg). He developed sudden perineal discomfort, fever with painful penile, and scrotal edema, subsequently leading to urinary retention. Read More

    Complete Genome Sequence of Streptococcus pyogenes emm14 JS95, a Necrotizing Fasciitis Strain Isolated in Israel.
    Genome Announc 2017 Mar 16;5(11). Epub 2017 Mar 16.
    Genome Institute of Singapore, Singapore
    Here, we report the complete genome sequence of the Streptococcus pyogenes emm14 strain JS95, isolated from a patient with necrotizing fasciitis. The streptococcal invasion locus (sil), the first quorum-sensing system characterized in S. pyogenes, was identified in this strain. Read More

    Periocular necrotizing fasciitis in an infant.
    Surv Ophthalmol 2017 Mar 11. Epub 2017 Mar 11.
    Department of Pathology, Duke University Medical Center, Durham, North Carolina, USA. Electronic address:
    Periocular necrotizing fasciitis developed in a 12-month-old boy with swelling of both eyes and redness and a discharge from the left eye approximately 36 hours after blunt trauma. Computed tomography revealed preseptal and soft-tissue edema on the left side, but no signs of orbital involvement, orbital fractures, or drainable abscess in the anterior left lower eyelid. The inflammatory signs worsened over the next day, and there was purulent discharge from the left lower eyelid and an abscess and necrosis of the lower eyelid skin. Read More

    Successful Treatment of Necrotizing Fasciitis and Streptococcal Toxic Shock Syndrome with the Addition of Linezolid.
    Case Rep Infect Dis 2017 19;2017:5720708. Epub 2017 Feb 19.
    University of Mississippi School of Pharmacy, 2500 North State Street, Jackson, MS, USA.
    Necrotizing fasciitis is a deep-seated subcutaneous tissue infection that is commonly associated with streptococcal toxic shock syndrome (TSS). Surgical debridement plus penicillin and clindamycin are the current standard of care. We report a case of necrotizing fasciitis and streptococcal TSS where linezolid was added after a failure to improve with standard therapy. Read More

    Clinical Characteristics and Outcomes of Patients With Cellulitis Requiring Intensive Care.
    JAMA Dermatol 2017 Mar 15. Epub 2017 Mar 15.
    Center for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands2Center for Infection and Immunity, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands3Division of Infectious Diseases, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
    Importance: Cellulitis is a commonly occurring skin and soft tissue infection and one of the most frequently seen dermatological diseases in the intensive care unit (ICU). However, clinical characteristics of patients with cellulitis requiring intensive care treatment are poorly defined. Necrotizing fasciitis is often confused for cellulitis at initial presentation and is considered to be more severe and thus has previously been described in more detail. Read More

    Healthcare Resource Utilization Associated with Burns and Necrotizing Fasciitis: A Single-Center Comparative Analysis.
    J Burn Care Res 2017 Mar 6. Epub 2017 Mar 6.
    From the *College of Medicine; †Manitoba Firefighters Burn Unit, Winnipeg, Canada; ‡College of Medicine; and §Department of Surgery, Sections of General and Plastic Surgery, University of Manitoba, Winnipeg, Canada.
    Necrotizing fasciitis (NF) patients are increasingly managed in burn units. Although treated similarly to burns, the healthcare resource utilization (HRU) in NF appears to be greater. Accurate knowledge of the HRU is important to better allocate resources and to compare outcomes between units. Read More

    Laboratory Risk Indicator for Necrotizing Fasciitis score for early diagnosis of necrotizing fasciitis in Darwin.
    ANZ J Surg 2017 Mar 15. Epub 2017 Mar 15.
    Department of Surgery, Royal Darwin Hospital, Darwin, Northern Territory, Australia.
    Background: Soft tissue infections are a major health burden in the Top End of the Northern Territory of Australia. Necrotizing fasciitis (NF) is associated with mortality rates from 8 to 40%. Early recognition and aggressive surgical debridement are the cornerstones of successful treatment. Read More

    [Necrotizing fasciitis in head and neck area].
    Magy Seb 2017 Mar;70(1):64-68
    Arc-, Állcsont- és Szájsebészeti, Fül-Orr-Gégészeti és Fej-Nyak Sebészeti Osztály, Bács-Kiskun Megyei Kórház 6000 Kecskemét, Nyíri út 38.
    Necrotizing fasciitis is a fulminant infection of the deeper layers of skin and subcutaneous tissues characterized by progressive soft tissue necrosis and high mortality. It rarely occurs in the head and neck area. The clinical picture includes non-specific but typical local and systemic symptoms. Read More

    A Case Report of the First Nonburn-related Military Trauma Victim Treated with Spray Skin Regenerative Therapy in Combination with a Dermal Regenerate Template.
    Plast Reconstr Surg Glob Open 2016 Dec 27;4(12):e1174. Epub 2016 Dec 27.
    Department of Plastic Surgery, The Ohio State Wexner Medical Center, Columbus, Ohio.; and Departments of Oral and Maxillofacial Surgery, Plastic and Reconstructive Surgery, and Orthopedic Surgery, Walter Reed National Military Medical Center, Bethesda, Md.
    Massive soft tissue and skin loss secondary to war-related traumas are among the most frequently encountered challenges in the care of wounded warriors. This case report outlines the first military nonburn-related trauma patient treated by a combination of regenerative modalities. Our case employs spray skin technology to an established dermal regenerate matrix. Read More

    [Necrotizing fasciitis of the upper and lower extremities].
    Chirurg 2017 Apr;88(4):353-366
    Klinik für Plastische Chirurgie und Schwerbrandverletzte, Handchirurgie-Zentrum, operatives Referenzzentrum für Gliedmaßentumoren, Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil, Ruhr-Universität Bochum, Bürkle-de-la-Camp-Platz 1, 44789, Bochum, Deutschland.
    Necrotizing fasciitis is a potentially fatal soft tissue infection that may affect the upper and lower extremities, scrotum, perineum and abdominal wall. Typically, the infection demonstrates rapid spreading along the fascial planes leading to sepsis with mortality rates of 15-46%. Without adequate treatment, the mortality rate increases to close to 100%. Read More

    Case series of Fournier's gangrene: Affected body surface area - The underestimated prognostic factor.
    Ann Med Surg (Lond) 2017 Apr 27;16:19-22. Epub 2017 Feb 27.
    Department of Surgery, Hospital Distrital da Figueira da Foz, 3094-001, Figueira da Foz, Portugal.
    Objectives: Identifying the factors affecting the outcome of patients with Fournier's Gangrene and assaying the accuracy of the Fournier Gangrene Severity Index (FGIS), the Uludag score (UdS), affected Body Surface Area (BSA) and the Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) model as prognostic tools.

    Materials And Methods: Retrospective study involving all patients with Fournier's gangrene treated in our Hospital between January 2008 and December 2015. The epidemiological, clinical, biochemical and management data of these patients was obtained and analyzed. Read More

    Pyoderma Gangrenosum or Necrotising Fasciitis? Diagnostic and Therapeutic Wanderings.
    Orthop Traumatol Surg Res 2017 Mar 9. Epub 2017 Mar 9.
    Service d'orthopédie-traumatologie. Hôpitaluniversitaire de Limoges, 2 Avenue Martin Luther King, 87000 Limoges, France.
    A case of post-traumatic lower-limb pyodermagangrenosum (PG) in a 77-year-old female is reported. The diagnosis of PG is frequently one of exclusion, and it is therefore unsurprising that the condition was initially mistaken for necrotising fasciitis then for necrotising bacterial dermo-hypodermitis. Medical and surgical treatment for those conditionsproved ineffective. Read More

    Evaluation of the Potency, Neutralizing Antibody Response, and Stability of a Recombinant Fusion Protein Vaccine for Streptococcus pyogenes.
    AAPS J 2017 Mar 10. Epub 2017 Mar 10.
    VaxForm, LLC, Bethlehem, Pennsylvania, USA.
    Streptococcus pyogenes or group A streptococcus (GAS) is a Gram-positive bacterium that can cause a wide range of diseases, including pharyngitis, impetigo, scarlet fever, necrotizing fasciitis, rheumatic fever, and streptococcal toxic shock syndrome. Despite the increasing burden on global health caused by GAS, there is currently no licensed vaccine available. In this study, we evaluated immunogenicity, induction of neutralizing antibodies, and stability of a new recombinant fusion protein vaccine that targets infections from GAS. Read More

    A double-blind randomized controlled trial of ibuprofen compared to placebo for uncomplicated cellulitis of the upper or lower limb.
    Clin Microbiol Infect 2017 Apr 6;23(4):242-246. Epub 2017 Mar 6.
    Global and Tropical Health Division, Menzies School of Health Research and Charles Darwin University, Darwin, Northern Territory, Australia; Victorian Infectious Diseases Service, The Royal Melbourne Hospital, and the University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
    Objectives: Cellulitis is a common skin infection resulting in inflammation that may take weeks to resolve despite appropriate antibiotics. It is unclear whether the adjunctive use of nonsteroidal anti-inflammatory drugs hastens the resolution of inflammation in patients with cellulitis.

    Methods: We conducted a double-blind, randomized controlled trial comparing ibuprofen 400 mg three times daily for 5 days with identical placebo in adults with uncomplicated cellulitis of the upper or lower limb who were treated with intravenous cefazolin via an outpatient parenteral antibiotic treatment service at one of two Australian hospitals. Read More

    The laboratory risk indicator for necrotizing fasciitis (LRINEC) scoring: the diagnostic and potential prognostic role.
    Scand J Trauma Resusc Emerg Med 2017 Mar 7;25(1):28. Epub 2017 Mar 7.
    Department of Surgery, trauma Surgery, HGH, Doha, Qatar.
    Background: Necrotizing fasciitis (NF) is a devastating soft tissue infection associated with potentially poor outcomes. The Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) score has been introduced as a diagnostic tool for NF. We aimed to evaluate the prognostic value of LRINEC scoring in NF patients. Read More

    Increased Pilus Production Conferred by a Naturally Occurring Mutation Alters Host-Pathogen Interaction in Favor of Carriage in Streptococcus pyogenes.
    Infect Immun 2017 May 21;85(5). Epub 2017 Apr 21.
    Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, Department of Pathology and Genomic Medicine, Houston Methodist, Houston, Texas, USA.
    Studies of the human pathogen group A Streptococcus (GAS) define the carrier phenotype to be an increased ability to adhere to and persist on epithelial surfaces and a decreased ability to cause disease. We tested the hypothesis that a single amino acid change (Arg135Gly) in a highly conserved sensor kinase (LiaS) of a poorly defined GAS regulatory system contributes to a carrier phenotype through increased pilus production. When introduced into an emm serotype-matched invasive strain, the carrier allele (the gene encoding the LiaS protein with an arginine-to-glycine change at position 135 [liaS(R135G)]) recapitulated a carrier phenotype defined by an increased ability to adhere to mucosal surfaces and a decreased ability to cause disease. Read More

    Peritonsillar abscess: clinical aspects of microbiology, risk factors, and the association with parapharyngeal abscess.
    Dan Med J 2017 Mar;64(3)
    PTA is a collection of pus located between the tonsillar capsule and the pharyngeal constrictor muscle. It is considered a complication of acute tonsillitis and is the most prevalent deep neck infection (approximately 2000 cases annually in Denmark) and cause of acute admission to Danish ENT departments. Teenagers and young adults are most commonly affected and males may predominate over females. Read More

    Microbiological aspects of Fournier's gangrene.
    Int J Surg 2017 Apr 28;40:135-138. Epub 2017 Feb 28.
    Uludag University School of Medicine, Department of Surgery, Gorukle, Bursa, 16059, Turkey.
    Background: Fournier's gangrene (FG) is a devastating disease that is characterized by necrotizing fasciitis of the perineal, genital, or perianal region. Broad-spectrum antibiotics are the key component of its treatment. However, there is paucity of data regarding the optimal empirical antibiotherapy for FG. Read More

    Abdominal wall necrotising fasciitis: A rare but devastating complication of the percutaneous endoscopic gastrostomy procedure.
    Med J Malaysia 2017 Feb;72(1):77-79
    UKM Medical Centre, Department of Medicine, Gastroenterology Unit, Jalan Yaacob Latiff, 56000 Cheras, Kuala Lumpur, Malaysia.
    Percutaneous Endoscopic Gastrostomy (PEG) tubes were often offered to patients requiring long term enteral feeding. Even though the procedure is relatively safe, it is associated with various complications such as peritonitis or even death.1 We presented a case of a 54-year-old gentleman with underlying ischemic stroke and pus discharges from a recently inserted PEG tube. Read More

    Necrotising fasciitis as a complication of odontogenic infection: a review of management and case series.
    Aust Dent J 2017 Feb 27. Epub 2017 Feb 27.
    Director, Oral and Maxillofacial Surgery Unit, Royal Adelaide Hospital, Adelaide, Australia.
    Objective: To establish the incidence of head and neck necrotising fasciitis (NF) in the Adelaide Oral and Maxillofacial Surgery Unit. To review the current literature regarding the management of head and neck NF. To determine the evidence for the role of hyperbaric oxygen therapy in the management of NF. Read More

    Effect of underlying immune compromise on the manifestations and outcomes of group A streptococcal bacteremia.
    J Infect 2017 May 22;74(5):450-455. Epub 2017 Feb 22.
    Division of Infectious Diseases, Department of Internal Medicine, University of Michigan Health System, USA. Electronic address:
    Background: Group A streptococcal bloodstream infection is the most common presentation of invasive group A streptococcal disease. We sought to determine the impact of immunosuppression on severity of disease and clinical outcomes.

    Methods: This retrospective review of 148 patients with at least one positive blood culture for Streptococcus pyogenes from 1/2003 to 3/2013 compared immunocompromised patients with those with no immunocompromise in regards to development of severe complications and mortality. Read More

    Retroperitoneal Necrotizing Fasciitis Masquerading as Perianal Abscess - Rare and Perilous.
    Cureus 2017 Jan 17;9(1):e982. Epub 2017 Jan 17.
    General Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.
    Necrotizing fasciitis is one of the uncommon presentations of a rapidly spreading subcutaneous tissue infection. Although the actual cause is unclear in many cases, most of them are due to the rapid proliferation of microorganisms. Retroperitoneal necrotizing fasciitis is extremely rare. Read More

    Early Diagnosis and Surgical Treatment for Necrotizing Fasciitis: A Multicenter Study.
    Front Surg 2017 7;4. Epub 2017 Feb 7.
    3rd Department of Surgery, Medical School, National and Kapodistrian University of Athens, Attikon University Hospital , Athens , Greece.
    Background: Necrotizing fasciitis (NF) is a group of relatively rare infections, usually caused by two or more pathogens. It affects the skin and subcutaneous tissues of lower and upper limbs, perineal area (Fournier's gangrene), and the abdominal wall. Early diagnosis and aggressive surgical management are of high significance for the management of this potentially lethal disease. Read More

    The spectrum and outcome of surgical sepsis in Pietermaritzburg, South Africa.
    S Afr Med J 2017 Jan 30;107(2):134-136. Epub 2017 Jan 30.
    Department of Surgery, Pietermaritzburg Hospital Complex and School of Clinical Medicine, College of Health Sciences, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.
    Background: Sepsis is a leading cause of morbidity and mortality worldwide, and the incidence appears to be increasing. In the resource-limited environment in low- and middle-income countries, the management of surgical sepsis (SS) continues to represent a significant portion of the workload for most general surgeons.

    Objective: To describe the spectrum of SS seen at a busy emergency department, and categorise the outcomes. Read More

    Negative pressure wound therapy: An update.
    Chin J Traumatol 2017 Apr 25;20(2):103-107. Epub 2017 Jan 25.
    Plastic Surgery Center, Faculty of Medicine, Mansoura University, Mansoura 35516, Egypt. Electronic address:
    Purpose: To get the maximum benefit of vacuum-assisted closure (VAC) in the management of acute and chronic wounds without abuse or misuse.

    Methods: Fourty one patients were included in the study. Among them, 9 patients had chronic wounds and the rest 32 patients had acute wounds. Read More

    Reconstruction of an Anterior Cervical Necrotizing Fasciitis Defect Using a Biodegradable Polyurethane Dermal Substitute.
    Eplasty 2017 25;17:e3. Epub 2017 Jan 25.
    Adult Burn Centre, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
    Introduction: Although we have previously described the use of a novel polyurethane biodegradable dermal substitute in the reconstruction of 20 free flap donor sites, and extensive cutaneous defects, including a large area of exposed calvarium secondary to burn injury, our experience with this material now extends to 35 free flap donor site reconstructions and 13 major or complex burns. Methods: The polyurethane material (NovoSorb BTM; PolyNovo Biomaterials Pty Ltd, Port Melbourne, Victoria, Australia) was recently employed in another complex wound scenario, implanted into a large anterior cervical cutaneous and soft-tissue defect remaining after serial radical debridement for necrotizing fasciitis. Results: Implantation, integration, delamination, and split-skin graft application proceeded without complication, mirroring our previous experience in other wounds (including major burns). Read More

    Contributing Factors for Complications and Outcomes in Patients With Snakebite: Experience in a Medical Center in Southern Taiwan.
    Ann Plast Surg 2017 Mar;78(3 Suppl 2):S32-S36
    From the *Division of Plastic and Reconstructive Surgery, Department of Surgery, Kaohsiung Veterans General Hospital, Kaohsiung; and †National Yang-Ming University, Taipei, Taiwan, Republic of China.
    Objectives: Snakebite usually results in various complications, such as significant soft tissue damage, infection, hematological, and neurological deficit. Surgical intervention, usually, is indicated in patients with tissue necrosis, infection, and compartment syndrome. To identify the contributing factors for complications and outcomes in different patients with snakebite so that outcomes can be evaluated and treatment of such patients can be initiated at the earliest. Read More

    Challenging Airway Secondary to Purpura Fulminans With Face and Neck Bullae in a Premature Infant: A Case Report.
    A A Case Rep 2017 Feb;8(4):70-71
    From the Departments of Pediatric Anesthesiology and Pediatric Plastic Surgery, Children's Memorial Hermann Hospital, McGovern Medical School, Houston, Texas.
    A former 25-week-old neonate presented at 34 weeks postconceptual age with necrotizing fasciitis and purpura fulminans because of Group B Streptococcus infection. He was septic and coagulopathic when he was intubated, and the endotracheal tube was secured with adhesives. When he subsequently developed large purpuric, bullous lesions on the face and neck, he presented to the operating room for excision and debridement of his facial lesions. Read More

    Application of a Silicone Sheet in Negative-Pressure Wound Therapy to Treat an Abdominal Wall Defect after Necrotizing Fasciitis.
    Arch Plast Surg 2017 Jan 20;44(1):76-79. Epub 2017 Jan 20.
    Department of Plastic and Reconstructive Surgery, Soonchunhyang University College of Medicine, Cheonan, Korea.
    Necrotizing fasciitis (NF) is an aggressive soft-tissue infection involving the deep fascia and is characterized by extensive deterioration of the surrounding tissue. Immediate diagnosis and intensive treatment, including debridement and systemic antibiotics, represent the most important factors influencing the survival of NF patients. In this report, we present a case of NF in the abdomen due to an infection caused by a perforated small bowel after abdominal liposuction. Read More

    1 OF 84