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    1 OF 85

    Pasteurella multocida ecthyma complicated by necrotizing fasciitis.
    Dermatol Online J 2017 Apr 15;23(4). Epub 2017 Apr 15.
    Medical Scientist Training Program, Ohio State University Wexner Medical Center, Columbus, Ohio, Department of Internal Medicine, Division of Dermatology, Ohio State University Wexner Medical Center, Columbus, Ohio.
    Necrotizing fasciitis is a serious infection of the skin and soft tissues. Pasteurella multocida is rarely reported to cause necrotizing fasciitis and is associated with high mortality. We describe a female patient with a past medical history of diabetes mellitus and myeloproliferative disorder presenting with bullae and erythema of the right forearm secondary to P. Read More

    Free tissue transfer for necrotizing fasciitis reconstruction: A case series.
    Burns 2017 May 20. Epub 2017 May 20.
    Manitoba Firefighters' Burn Unit, Health Sciences Centre, Winnipeg, Manitoba, Canada; Section of Plastic Surgery, Department of Surgery, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada; Section of General Surgery, Department of Surgery, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada. Electronic address:
    Background: Necrotizing fasciitis (NF) is a life-threatening infection requiring extensive debridement that may necessitate amputation. Free tissue transfer (FTT) is an option for reconstruction in difficult cases. Currently, only case reports have described FTT in the setting of NF, and comprehensive evidence on flap outcomes is lacking. Read More

    Diabetic Muscle Infarction Masquerading as Necrotizing Fasciitis.
    Case Rep Nephrol 2017 26;2017:7240156. Epub 2017 Apr 26.
    Department of Infectious Disease, Maimonides Medical Center, Brooklyn, NY, USA.
    A 43-year-old male patient with past medical history of diabetes mellitus (DM), end stage renal disease (ESRD) on hemodialysis (HD), congestive heart failure (CHF), obstructive sleep apnea (OSA), and chronic anemia presented with complaints of left thigh pain. A computerized tomogram (CT) of the thigh revealed evidence of edema with no evidence of a focal collection or gas formation noted. The patient's clinical symptoms persisted and he underwent magnetic resonance imaging (MRI) of his thigh which was reported to show small areas of muscle necrosis with fluid collection. Read More

    Magnetic resonance imaging of painful swollen legs in the emergency department: a pictorial essay.
    Emerg Radiol 2017 May 18. Epub 2017 May 18.
    Department of Diagnostic Radiology, Khoo Teck Puat Hospital, 90 Yishun Central, Singapore, 768828, Singapore.
    Patients presenting with a painful swollen leg are not infrequently encountered at the emergency department and can pose a diagnostic dilemma for attending physicians. The potential causes of leg pain and swelling include trauma, infection, inflammation, and neurogenic, vascular, and iatrogenic conditions; with magnetic resonance imaging (MRI) being an important tool in evaluation. We describe the MRI features of various conditions causing painful swollen legs. Read More

    Lethal Necrotizing Fasciitis Triggered by Plaster: Case Report and Review of Literature.
    J Orthop Case Rep 2016 Nov-Dec;6(5):73-75
    Department of Orthopaedics, V. S. Hospital, and N. H. L. Medical College, Ahmedabad, India.
    Introduction: Plasters have been frequently associated with known complications such as infection, and compartment syndrome or deep vein thrombosis. However, life-threatening complication of necrotizing fasciitis (NF) has not been frequently attributed to plaster.

    Case Report: We had a case of a 62-year male developing a lethal NF triggered by a below knee plaster for undisplaced fracture medial malleolus after twisting injury. Read More

    Cadaver-based Necrotizing Fasciitis Model for Medical Training.
    Cureus 2017 Apr 14;9(4):e1168. Epub 2017 Apr 14.
    Department of Emergency Medicine, University of Arizona.
    Necrotizing fasciitis is a devastating infectious disease process that is characterized by extensive soft tissue necrosis along deep fascial planes, systemic toxicity, and high mortality. Ultrasound imaging is a rapid and non-invasive tool that can be used to help make the diagnosis of necrotizing fasciitis by identifying several distinctive sonographic findings. The purpose of this study is to describe the construction of a realistic diagnostic training model for necrotizing fasciitis using fresh frozen cadavers and common, affordable materials. Read More

    Necrotizing fasciitis: treatment concepts and clinical results.
    Eur J Trauma Emerg Surg 2017 May 8. Epub 2017 May 8.
    Department of Trauma, Hand, and Reconstructive Surgery, Johann Wolfgang Goethe-University, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany.
    Background: Necrotizing fasciitis is a life-threatening soft tissue infection characterized by a rapid spreading infection of the subcutaneous tissue and in particular the fascia. The management of infected tissues requires a rapid diagnosis, immediate aggressive surgical management and an extended debridement. In some cases early amputations of the affected tissues and maximum intensive care treatment, in case of sepsis, are required. Read More

    Cervical Necrotizing Fasciitis: A Potentially Fatal Disease with Varied Etiology.
    Ann Med Health Sci Res 2016 Jul-Aug;6(4):251-256
    Department of Dental and Maxillofacial Surgery, Usmanu Danfodiyo University, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria.
    Necrotizing fasciitis was recognized centuries ago by physicians. It is a rapidly progressive and potentially fatal soft-tissue infection that is typified by soft-tissue necrosis, especially affecting the subcutaneous tissues and fascia. Cervico-facial necrotizing fasciitis is said to be uncommon, but when it occurs, it is often of odontogenic origin and has severe consequences if not promptly treated. Read More

    Necrotizing fasciitis resulting in fatal lung aspergillosis: Uncommon pathogenesis. A case report.
    J Mycol Med 2017 May 4. Epub 2017 May 4.
    Department of Plastic Surgery, Hand Surgery and Burn Center, Faculty of Medicine, RWTH Aachen University Hospital, Pauwelsstrasse 30, 52074 Aachen, Germany.
    We present a fatal case of Aspergillus-associated lung failure in a patient with necrotizing fasciitis. The cause of the fasciitis was a retroperitoneal perforation of a colon carcinoma. Being already a rare condition, the fasciitis did not manifest as Fournier's gangrene like similar described cases illustrate, but instead travelled along the fasciae and subcutaneous fat tissue cranially into the thoracic cavity, ultimately leading to a disseminated infection of the lungs. Read More

    A rare case report of vulvar necrotizing fasciitis in a healthy patient.
    Int J Surg Case Rep 2017 18;35:103-105. Epub 2017 Apr 18.
    Department of Surgery - Division of General, Minimally Invasive & Robotic Surgery, University of Illinois at Chicago, 840 S. Wood Street, Suite 435E (M/C958), Chicago, IL 60612, USA. Electronic address:
    Introduction: Necrotizing fasciitis (NF), a necrotizing infection of the soft tissue, is a medical emergency usually occurring in the lower extremities and abdominal regions and often difficult to diagnose promptly.

    Presentation Of Case: This case report looks at one atypical presentation of NF with the unusual location of the vulva and no known associated comorbidities or risk factors.

    Discussion: Diagnosing this patient was particularly difficult due to the inconsistent clinical, laboratory and imaging findings. Read More

    Acute Cutaneous Necrosis: A Guide to Early Diagnosis and Treatment.
    J Cutan Med Surg 2017 May 1:1203475417708164. Epub 2017 May 1.
    4 University of Missouri Kansas City, Department of Internal Medicine, Kansas City, MO, USA.
    Acute cutaneous necrosis is characterised by a wide range of aetiologies and is associated with significant morbidity and mortality, warranting complex considerations in management. Early recognition is imperative in diagnosis and management of sudden gangrenous changes in the skin. This review discusses major causes of cutaneous necrosis, examines the need for early assessment, and integrates techniques related to diagnosis and management. Read More

    Rapid Emergence of a New Clone Impacts the Population at Risk and Increases the Incidence of Type emm89 Group A Streptococcus Invasive Disease.
    Open Forum Infect Dis 2017 4;4(2):ofx042. Epub 2017 Mar 4.
    Public Health Ontario, Toronto, Canada.
    Background: Invasive group A Streptococcus (iGAS) disease caused by type emm89 strains has been increasing worldwide, driven by the emergence of an epidemic clonal variant (clade 3 emm89). The clinical characteristics of patients with emm89 iGAS disease, and in particular with clade 3 emm89 iGAS disease, are poorly described.

    Methods: We used population-based iGAS surveillance data collected in metropolitan Toronto, Ontario, Canada during the period 2000-2014. Read More

    Laboratory risk indicator for necrotising fasciitis (LRINEC) score for the assessment of early necrotising fasciitis: a systematic review of the literature.
    Ann R Coll Surg Engl 2017 May;99(5):341-346
    Queen Elizabeth Hospital, Edgbaston, Birmingham, UK.
    Introduction Early operative debridement of necrotising fasciitis is a major outcome determinant. Identification and diagnosis of such patients can be clinically difficult. The Laboratory Risk Indicator for Necrotising Fasciitis (LRINEC) score first published in 2004 is based on routinely performed parameters and offers a method for identifying early cases. Read More

    Whole genome sequencing of group A Streptococcus: development and evaluation of an automated pipeline for emmgene typing.
    PeerJ 2017 27;5:e3226. Epub 2017 Apr 27.
    Respiratory and Vaccine Preventable Bacterial Reference Unit, Public Health England, London, United Kingdom.
    Streptococcus pyogenes group A Streptococcus (GAS) is the most common cause of bacterial throat infections, and can cause mild to severe skin and soft tissue infections, including impetigo, erysipelas, necrotizing fasciitis, as well as systemic and fatal infections including septicaemia and meningitis. Estimated annual incidence for invasive group A streptococcal infection (iGAS) in industrialised countries is approximately three per 100,000 per year. Typing is currently used in England and Wales to monitor bacterial strains of S. Read More

    Candida parapsilosis associated with cervical necrotizing fasciitis and descending mediastinitis.
    J Surg Case Rep 2017 Apr 20;2017(4):rjx065. Epub 2017 Apr 20.
    Department of Surgery, Queen Mary Hospital, The University of Hong Kong, Hong Kong.
    Background: This report presents an immunocompetent lady suffering from Candida parapsilosis associated with polybacterial cervical necrotizing fasciitis and descending mediastinitis. A literature review and management of invasive candidiasis is discussed.

    Methods: A 57-year-old healthy lady presented with cervical necrotizing fasciitis and descending mediastinitis. Read More

    Mortality of Necrotising Fasciitis: relative influence of individual and hospital-level factors, a Nationwide Multi-Level Study, France, 2007-2012.
    Br J Dermatol 2017 Apr 27. Epub 2017 Apr 27.
    AP-HP, Hôpitaux universitaires Henri Mondor, Département de Dermatologie, Créteil, F-94010, France.
    Background: Necrotising soft-tissue infections (NSTI) are rare, life-threatening conditions.

    Objectives: We aimed to assess whether admitting hospital characteristics were associated with NSTI mortality.

    Methods: We studied the French nationwide hospital discharge database (retrospective national cohort). Read More

    Ten-year follow-up of a case of necrotizing fasciitis successfully treated with negative-pressure wound therapy, dermal regeneration template application, and split- thickness skin autograft.
    Acta Chir Belg 2017 Apr 25:1-5. Epub 2017 Apr 25.
    a Department of Plastic and Reconstructive Surgery , Brugmann University Hospital, Free University of Brussels , Brussels , Belgium.
    Introduction: Necrotizing fasciitis is a rapidly progressive and often fatal infection of the fasciae and subcutaneous tissues.

    Patient And Methods: In this case report, we present the treatment of a 63-year-old patient suffering from diabetes mellitus, who was admitted to the emergency unit for severe right gluteal pain, which had begun 24 hours before admission. Cutaneous symptoms, oliguria, metabolic acidosis, acute renal failure, severe hypotension, and tachycardia occurred, and the patient was admitted to Intensive Care a few hours after initial admission. Read More

    Looking Beyond the Cell in Cellulitis.
    Adv Skin Wound Care 2017 May;30(5):209-212
    Vincent Maida, MD, MSc, BSc, CCFP(PC), FCFP, ABHPM, is Associate Professor, Division of Palliative Care, University of Toronto; and Clinical Assistant Professor, Division of Palliative Care, McMaster University and Division of Palliative Medicine, William Osler Health System, Toronto, Ontario, Canada. Joyce T. W. Cheung, MD, BSc, CCFP, is a Palliative Medicine Consultant, Division of Palliative Medicine, William Osler Health System, Toronto, Ontario, Canada.
    Background: Patients with erythematous skin are likely to receive a diagnosis of cellulitis; however, the accuracy of this diagnosis is approximately only 33%. The diagnosis of cellulitis should be made only after a thorough evaluation of all possible differential diagnoses. Cellulitis may be a primary process (superficial spreading infective process involving only the epidermis and dermis) versus a secondary (reactive) process incited by a subcutaneous process, such as an abscess, tenosynovitis, necrotizing fasciitis, and osteomyelitis. Read More

    Immunoglobulin G for patients with necrotising soft tissue infection (INSTINCT): a randomised, blinded, placebo-controlled trial.
    Intensive Care Med 2017 Apr 18. Epub 2017 Apr 18.
    Department of Intensive Care, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.
    Purpose: The aim of the INSTINCT trial was to assess the effect of intravenous polyspecific immunoglobulin G (IVIG) compared with placebo on self-reported physical function in intensive care unit (ICU) patients with necrotising soft tissue infection (NSTI).

    Methods: We randomised 100 patients with NSTI 1:1 to masked infusion of 25 g of IVIG (Privigen, CSL Behring) or an equal volume of 0.9% saline once daily for the first 3 days of ICU admission. Read More

    Management of necrotising fasciitis secondary to abdominal liposuction using a combination of surgery, hyperbaric oxygen and negative pressure wound therapy in a patient with burn scars.
    Int Wound J 2017 Apr 17. Epub 2017 Apr 17.
    Division of Plastic and Reconstructive Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
    Liposuction is the one of the most frequently performed cosmetic operations and usually has an easy recovery, with a reportedly low overall complication rate. Here, we report the case of a 60-year-old woman with type II diabetes mellitus and a previous burn injury of the abdomen who underwent abdominal liposuction and subsequently developed necrotising fasciitis. Following radical debridement, systemic antibiotic administration, negative pressure wound therapy and hyperbaric oxygen therapy, the wound healed completely. Read More

    A Rare Case of Tropical Pyomysitis Acquired on Vacation in a Healthy Male.
    J La State Med Soc 2017 Mar-Apr;169(2):53. Epub 2017 Apr 15.
    Department of Internal Medicine, Ochsner Medical Center, New Orleans, LA.
    Introduction: Pyomyositis has traditionally been considered a tropical disease. Increasing prevalence has been observed in more northern climates, especially with HIV, immunosuppression, and IV drug abuse as predisposing factors. Pyomyositis has the tendency to mimic other conditions, such as muscle contusion, necrotizing fasciitis, or septic arthritis. Read More

    A Rare Case of Raoultella planticola Pneumonia: An Emerging Pathogen.
    Respir Med Case Rep 2017 28;21:69-70. Epub 2017 Mar 28.
    University of Florida College of Medicine, Division of Pulmonology, Critical Care and Sleep Medicine, USA.
    Raoultella planticola (R. planticola), considered an environmental organism, is a gram negative, motile, bacillus with phenotypic similarities to the genus Klebsiella. The organism remains a rare cause of human infection with a few cases reported in the literature. Read More

    Skin diseases of the vulva: Infectious diseases.
    J Obstet Gynaecol 2017 Apr 11:1-9. Epub 2017 Apr 11.
    a Department of Dermatology , Bispebjerg Hospital , Copenhagen , Denmark.
    A multitude of infectious diseases of viral (genital herpes, herpes zoster, genital warts and molluscum contagiosum), bacterial (syphilis, chancroid, lymphogranuloma venereum, donovanosis, erysipelas, cellulitis and necrotising fasciitis, folliculitis, impetigo, bartholin gland abscess, trichomycosis and erythrasma), fungal (candidiasis and dermatophytosis) and parasitic (pediculosis pubis) origin may affect the vulvar area. Herein, we review the infections and their skin manifestations in the vulvar area. Read More

    Postsurgical Pyoderma Gangrenosum Versus Necrotizing Fasciitis: Can We Spot the Difference?
    Ann Plast Surg 2017 May;78(5):582-586
    From the Department of Plastic Surgery, Countess of Chester Hospital, Chester, PA.
    Background: Pyoderma gangrenosum is a rare noninfectious cutaneous disease characterized by expanding areas of skin ulceration around necrotic centers with purulent debris. Exceptionally, it can be precipitated by surgery alone, and this entity has been described as postsurgical pyoderma gangrenosum (PSPG). Cases of PSPG in the literature are rare. Read More

    Management and Novel Adjuncts of Necrotizing Soft Tissue Infections.
    Surg Infect (Larchmt) 2017 Apr 4;18(3):250-272. Epub 2017 Apr 4.
    Department of Surgery, University of Pittsburgh , Pittsburgh, Pennsylvania.
    Necrotizing soft tissue infections (NSTI) have been recognized for millennia and continue to impose considerable burden on both patient and society in terms of morbidity, death, and the allocation of resources. With improvements in the delivery of critical care, outcomes have improved, although disease-specific therapies are lacking. The basic principles of early diagnosis, of prompt and broad antimicrobial therapy, and of aggressive debridement have remained unchanged. Read More

    Air and its Sonographic Appearance: Understanding the Artifacts.
    J Emerg Med 2017 Mar 31. Epub 2017 Mar 31.
    Department of Emergency Medicine, Division of Emergency Ultrasound, Mount Sinai St. Luke's Hospital, Mount Sinai West Hospital, New York, New York.
    Background: Although air has traditionally been considered a barrier to sonographic imaging, when encountered in unusual settings it can serve as an important indicator of various pathologic states as well. Clinician recognition and thorough understanding of the characteristic pattern of artifacts generated by air are critical for making a number of important diagnoses.

    Case Series: We present five emergency department cases in which air was visualized in a pathologic location. Read More

    Radiologic Approach to Musculoskeletal Infections.
    Infect Dis Clin North Am 2017 Jun 30;31(2):299-324. Epub 2017 Mar 30.
    Section of Musculoskeletal Radiology, Imaging Institute, Cleveland Clinic, CCLCM/CWRU, 9500 Euclid Avenue, Cleveland, OH 44195, USA. Electronic address:
    Imaging is often used to establish a diagnosis of musculoskeletal infections and evaluate the full extent and severity of disease. Imaging should always start with radiographs, which provide an important anatomic overview. MRI is the test of choice in most musculoskeletal infections because of its superior soft tissue contrast resolution and high sensitivity for pathologic edema. Read More

    An Eye Popping Case of Orbital Necrotizing Fasciitis Treated with Antibiotics, Surgery, and Hyperbaric Oxygen Therapy.
    Am J Case Rep 2017 Apr 1;18:329-333. Epub 2017 Apr 1.
    Department of Internal Medicine, University of Cincinnati, Cincinnati, OH, USA.
    BACKGROUND Necrotizing fasciitis (NF) of the orbit is a rare and deadly condition that requires prompt surgical and medical management to decrease morbidity and mortality.  CASE REPORT Here we present an interesting case of an individual who developed fulminant NF of the left orbit requiring emergent surgical intervention, antibiotics, and subsequent hyperbaric oxygen therapy in an attempt to save the eye.  CONCLUSIONS With an early and aggressive multifaceted approach using antibiotics, surgery, and hyperbaric oxygen it may be possible to preserve eye structure and function. Read More

    Acute Chest Wall Infections: Surgical Site Infections, Necrotizing Soft Tissue Infections, and Sternoclavicular Joint Infection.
    Thorac Surg Clin 2017 May;27(2):73-86
    Section of General Thoracic Surgery, Division of Cardiothoracic Surgery, Department of Surgery, Oregon Health and Sciences University, 3181 SW Sam Jackson Park Road L353, Portland, OR 97239, USA.
    Acute chest wall infections are uncommon and share similar risk factors for infection at other surgical sites. Smoking cessation has been shown to decrease the risk of surgical site infection. Depending on the depth of infection and/or involvement of the organ space, adequate therapy involves antibiotics and drainage. Read More

    Immunization with a streptococcal multiple-epitope recombinant protein protects mice against invasive group A streptococcal infection.
    PLoS One 2017 29;12(3):e0174464. Epub 2017 Mar 29.
    Department of Biological Science and Technology, College of Medicine, I-Shou University, Kaohsiung, Taiwan.
    Streptococcus pyogenes (group A Streptococcus; GAS) causes clinical diseases, including pharyngitis, scarlet fever, impetigo, necrotizing fasciitis and streptococcal toxic shock syndrome. A number of group A streptococcus vaccine candidates have been developed, but only one 26-valent recombinant M protein vaccine has entered clinical trials. Differing from the design of a 26-valent recombinant M protein vaccine, we provide here a vaccination using the polyvalence epitope recombinant FSBM protein (rFSBM), which contains four different epitopes, including the fibronectin-binding repeats domain of streptococcal fibronectin binding protein Sfb1, the C-terminal immunogenic segment of streptolysin S, the C3-binding motif of streptococcal pyrogenic exotoxin B, and the C-terminal conserved segment of M protein. Read More

    Haemophilus influenzae Pyomyositis in a Patient with Diabetic Ketoacidosis: A Unique Case and Review of Literature.
    Case Rep Infect Dis 2017 2;2017:6307361. Epub 2017 Mar 2.
    Department of Infectious Disease, Einstein Medical Center, Philadelphia, PA, USA.
    Haemophilus influenzae is a Gram-negative bacillus commonly known to cause upper respiratory tract infections. Skin and soft tissue infections are very uncommon. Of these, the majority were associated with necrotizing fasciitis requiring emergent debridement. Read More

    Necrotising fasciitis after laparoscopic rectal cancer surgery.
    Ann R Coll Surg Engl 2017 Apr;99(4):e113-e114
    Mid Yorkshire Hospitals NHS Trust , UK.
    Necrotising fasciitis is a rare, serious infection of the deep fascia leading to subcutaneous tissue necrosis. It is extremely important for this condition to be identified and treated promptly as it bears significant mortality. We describe a case of necrotising fasciitis after laparoscopic rectal cancer surgery. Read More

    Cutaneous manifestations of disseminated gonococcemia.
    Dermatol Online J 2017 Jan 15;23(1). Epub 2017 Jan 15.
    Medical School, Louisiana State University Health Sciences Center, New Orleans.
    Background: Sexually transmitted infections, includingurogenital gonorrheal infection, are a growing healthconcern in the United States. Nearly 50% of cervicalinfections are asymptomatic. If left undiagnosedand untreated, there is a risk of disseminatedinfection. Read More

    Myelodysplastic syndrome diagnosed on the occasion of Fournier's gangrene.
    Rinsho Ketsueki 2017;58(2):113-118
    Hematology Division, JCHO Sapporo Hokushin Hospital.
    Fournier's gangrene (FG) is a fulminant infective necrotizing fasciitis, which includes the genital, perineal, and perianal regions. A 77-year-old man had previously been diagnosed as having diabetes mellitus (DM) and was treated with pioglitazone (15 mg) and miglitol (150 mg). He developed sudden perineal discomfort, fever with painful penile, and scrotal edema, subsequently leading to urinary retention. Read More

    Complete Genome Sequence of Streptococcus pyogenes emm14 JS95, a Necrotizing Fasciitis Strain Isolated in Israel.
    Genome Announc 2017 Mar 16;5(11). Epub 2017 Mar 16.
    Genome Institute of Singapore, Singapore
    Here, we report the complete genome sequence of the Streptococcus pyogenes emm14 strain JS95, isolated from a patient with necrotizing fasciitis. The streptococcal invasion locus (sil), the first quorum-sensing system characterized in S. pyogenes, was identified in this strain. Read More

    Periocular necrotizing fasciitis in an infant.
    Surv Ophthalmol 2017 Mar 11. Epub 2017 Mar 11.
    Department of Pathology, Duke University Medical Center, Durham, North Carolina, USA. Electronic address:
    Periocular necrotizing fasciitis developed in a 12-month-old boy with swelling of both eyes and redness and a discharge from the left eye approximately 36 hours after blunt trauma. Computed tomography revealed preseptal and soft-tissue edema on the left side, but no signs of orbital involvement, orbital fractures, or drainable abscess in the anterior left lower eyelid. The inflammatory signs worsened over the next day, and there was purulent discharge from the left lower eyelid and an abscess and necrosis of the lower eyelid skin. Read More

    Successful Treatment of Necrotizing Fasciitis and Streptococcal Toxic Shock Syndrome with the Addition of Linezolid.
    Case Rep Infect Dis 2017 19;2017:5720708. Epub 2017 Feb 19.
    University of Mississippi School of Pharmacy, 2500 North State Street, Jackson, MS, USA.
    Necrotizing fasciitis is a deep-seated subcutaneous tissue infection that is commonly associated with streptococcal toxic shock syndrome (TSS). Surgical debridement plus penicillin and clindamycin are the current standard of care. We report a case of necrotizing fasciitis and streptococcal TSS where linezolid was added after a failure to improve with standard therapy. Read More

    Clinical Characteristics and Outcomes of Patients With Cellulitis Requiring Intensive Care.
    JAMA Dermatol 2017 Mar 15. Epub 2017 Mar 15.
    Center for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands2Center for Infection and Immunity, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands3Division of Infectious Diseases, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
    Importance: Cellulitis is a commonly occurring skin and soft tissue infection and one of the most frequently seen dermatological diseases in the intensive care unit (ICU). However, clinical characteristics of patients with cellulitis requiring intensive care treatment are poorly defined. Necrotizing fasciitis is often confused for cellulitis at initial presentation and is considered to be more severe and thus has previously been described in more detail. Read More

    Healthcare Resource Utilization Associated with Burns and Necrotizing Fasciitis: A Single-Center Comparative Analysis.
    J Burn Care Res 2017 Mar 6. Epub 2017 Mar 6.
    From the *College of Medicine; †Manitoba Firefighters Burn Unit, Winnipeg, Canada; ‡College of Medicine; and §Department of Surgery, Sections of General and Plastic Surgery, University of Manitoba, Winnipeg, Canada.
    Necrotizing fasciitis (NF) patients are increasingly managed in burn units. Although treated similarly to burns, the healthcare resource utilization (HRU) in NF appears to be greater. Accurate knowledge of the HRU is important to better allocate resources and to compare outcomes between units. Read More

    Laboratory Risk Indicator for Necrotizing Fasciitis score for early diagnosis of necrotizing fasciitis in Darwin.
    ANZ J Surg 2017 Mar 15. Epub 2017 Mar 15.
    Department of Surgery, Royal Darwin Hospital, Darwin, Northern Territory, Australia.
    Background: Soft tissue infections are a major health burden in the Top End of the Northern Territory of Australia. Necrotizing fasciitis (NF) is associated with mortality rates from 8 to 40%. Early recognition and aggressive surgical debridement are the cornerstones of successful treatment. Read More

    [Necrotizing fasciitis in head and neck area].
    Magy Seb 2017 Mar;70(1):64-68
    Arc-, Állcsont- és Szájsebészeti, Fül-Orr-Gégészeti és Fej-Nyak Sebészeti Osztály, Bács-Kiskun Megyei Kórház 6000 Kecskemét, Nyíri út 38.
    Necrotizing fasciitis is a fulminant infection of the deeper layers of skin and subcutaneous tissues characterized by progressive soft tissue necrosis and high mortality. It rarely occurs in the head and neck area. The clinical picture includes non-specific but typical local and systemic symptoms. Read More

    A Case Report of the First Nonburn-related Military Trauma Victim Treated with Spray Skin Regenerative Therapy in Combination with a Dermal Regenerate Template.
    Plast Reconstr Surg Glob Open 2016 Dec 27;4(12):e1174. Epub 2016 Dec 27.
    Department of Plastic Surgery, The Ohio State Wexner Medical Center, Columbus, Ohio.; and Departments of Oral and Maxillofacial Surgery, Plastic and Reconstructive Surgery, and Orthopedic Surgery, Walter Reed National Military Medical Center, Bethesda, Md.
    Massive soft tissue and skin loss secondary to war-related traumas are among the most frequently encountered challenges in the care of wounded warriors. This case report outlines the first military nonburn-related trauma patient treated by a combination of regenerative modalities. Our case employs spray skin technology to an established dermal regenerate matrix. Read More

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