4,958 results match your criteria Necrotizing Fasciitis


Necrotising fasciitis in a ten month old infant.

Urol Case Rep 2020 Sep 10;32:101245. Epub 2020 May 10.

Head of Clinical Unit, Department of Urology, Port Elizabeth Provincial Hospital, South Africa.

Necrotising Fasciitis, also known as Fournier's Gangrene (FG), is a condition that rarely affects children. FG was first described by French venereologist, Jean Alfred Fournier in 1883. It is more common in adults and is strongly linked to immunosuppression. Read More

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http://dx.doi.org/10.1016/j.eucr.2020.101245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260423PMC
September 2020

Combined Timed Surgery and Conservative Management of Primary Necrotizing Fasciitis of the Breast: A Case Report.

Am J Case Rep 2020 Jun 3;21:e922688. Epub 2020 Jun 3.

Department of Public Health, Sector of Plastic Surgery, University of Naples "Federico II", Naples, Italy.

BACKGROUND Necrotizing fasciitis is a life-threatening infection that involves the deep fascia and the surrounding tissue, but rarely involves the female breast. The most common treatment for necrotizing fasciitis of the breast is total mastectomy. However, the use of negative pressure wound therapy (NPWT), after surgical debridement, is reported to promote the more rapid development of granulation tissue, before reconstructive surgery. Read More

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http://dx.doi.org/10.12659/AJCR.922688DOI Listing

Near-fatal poisoning after ricin injection.

Clin Toxicol (Phila) 2020 Jun 1:1-11. Epub 2020 Jun 1.

Campinas Poison Control Center, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.

To report a near-fatal poisoning after intentional injection of ricin from a castor bean () extract. A 21 year-old man self-injected ∼3 mL of a castor bean extract intramuscularly and subcutaneously in the left antecubital fossa. Upon admission to our ED (1 h post-exposure; day 1, D1) he was awake and alert, but complained of mild local pain and showed slight local edema and erythema. Read More

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http://dx.doi.org/10.1080/15563650.2020.1771358DOI Listing

Historical and Clinical Perspective of Infections in Korea.

Infect Chemother 2020 05 29. Epub 2020 May 29.

Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

infection was first reported as a necrotizing skin disease of unknown cause in Korea in 1979. In the early days, this disease caused panic across the country due to dreadful wound and its high mortality. Since then, the nature of the disease has become better understood and the overwhelming public fear has dissipated. Read More

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Severe Lower Extremity Cellulitis Caused by an Unusual Pathogen: Haemophilus Influenzae Type F.

Cureus 2020 Apr 24;12(4):e7819. Epub 2020 Apr 24.

Infectious Diseases, St. Barnabas Hospital Health System, Bronx, USA.

We present a case of unusual cellulitis of the lower extremities caused by (HI). A 64-year-old female with human immunodeficiency virus (HIV) with a suppressed viral load on treatment, presented with severe, very painful cellulitis of her lower extremity. CT scan did not show any gas or collections; however, she was taken to the operating room for concern of necrotizing fasciitis but no evidence of deep tissue involvement was found. Read More

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http://dx.doi.org/10.7759/cureus.7819DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249777PMC

: a rare cause of necrotising fasciitis.

BMJ Case Rep 2020 May 27;13(5). Epub 2020 May 27.

General Surgery, North Tees and Hartlepool NHS Foundation Trust, Stockton-on-Tees, UK.

Necrotising fasciitis is a life-threatening condition characterised by inflammation, affecting the soft tissues, which spreads within a fascial plane. Skin changes can be delayed and can often go unnoticed. The condition arises from a bacterial infection, commonly being of polymicrobial aetiology. Read More

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http://dx.doi.org/10.1136/bcr-2020-235115DOI Listing

Axillary Approach for Venoarterial Extracorporeal Membrane Oxygenation Cannulation.

Cureus 2020 Apr 22;12(4):e7788. Epub 2020 Apr 22.

Cardiology/Internal Medicine, University of Maryland, Baltimore, USA.

Extracorporeal membrane oxygenation support (ECMO) is a form of mechanical circulatory support that is used in patients with severe dysfunction of heart or lung or both. Depending on whether it is venovenous or venoarterial support, it can temporarily substitute for circulation and ventilation while the underlying cause is addressed. Traditional approach for cannulation usually involves the femoral vessels. Read More

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http://dx.doi.org/10.7759/cureus.7788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243636PMC

Necrotizing Fasciitis: A Predictable Burden in Rural Kenya.

World J Surg 2020 May 20. Epub 2020 May 20.

Department of Surgery, Tenwek Hospital, P.O. Box 39, Bomet, 20400, Kenya.

Background: Necrotizing fasciitis (NF) is a devastating disease with substantial morbidity and mortality. Poor outcomes are attributed to delayed diagnosis and management. Tenwek Hospital, a teaching and referral center in rural Kenya, manages many cases despite variable resources. Read More

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http://dx.doi.org/10.1007/s00268-020-05581-4DOI Listing

in Gas Gangrene: Still a Smoked Gun!

J Transl Int Med 2020 Mar 9;8(1):54-56. Epub 2020 May 9.

Intensive care Departement, Brugmann University Hospital, Brussels, Belgium.

Gas gangrene (GG) remains a life-threatening and deadly disease. Early recognition together with daily surgical debridement remains the mainstay of therapy. We sought to describe a fatal case of necrotizing soft tissue infection, which was a gas gagrene in this case. Read More

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http://dx.doi.org/10.2478/jtim-2020-0009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227166PMC

Meningococcaemia causing necrotizing cellulitis associated with acquired complement deficiency after gastric bypass surgery: a case report.

BMC Infect Dis 2020 May 20;20(1):361. Epub 2020 May 20.

Department of Intensive Care, Erasme Hospital, Université Libre de Bruxelles, 808 Route de Lennik, Brussels, Belgium.

Background: Neisseria meningitidis has rarely been described as an agent of necrotic soft tissue infection.

Case Presentation: We report a case of a septic shock with necrotizing cellulitis due to Neisseria meningitidis serogroup W, treated by urgent extensive surgical debridement followed by skin grafts. The invasive meningococcal disease occurred together with a complement deficiency, possibly acquired after bypass surgery that took place 1 year before. Read More

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http://dx.doi.org/10.1186/s12879-020-05079-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240913PMC

A Severe Case of Ludwig's Angina with a Complicated Clinical Course.

Authors:
Vitaley Kovalev

Cureus 2020 Apr 16;12(4):e7695. Epub 2020 Apr 16.

Acute Care Surgery, California Hospital Medical Center, Los Angeles, USA.

Ludwig's angina is a cellulitis of the submandibular, sublingual, and submental spaces, which tends to spread rapidly along fascial planes. The most common cause is a dental infection, although any other oropharyngeal infection has the potential to develop into Ludwig's angina. The most feared complication of Ludwig's angina is airway obstruction. Read More

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http://dx.doi.org/10.7759/cureus.7695DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7233510PMC

From acute management to ultimate reconstruction: a 15-year follow-up of a pediatric patient with necrotizing fasciitis secondary to varicella infection.

Ann Burns Fire Disasters 2019 Dec;32(4):331-334

American University of Beirut Medical Center, Beirut, Lebanon.

Necrotizing fasciitis is a rapidly progressive, life-threatening soft tissue infection. The usually aggressive surgical debridement often leaves disfiguring sequelae.We hereby present the case of a 4-yearold boy who presented with post varicella zoster necrotizing fasciitis over his trunk, and follow his journey post reconstruction with split thickness skin grafts and the sequelae of grafting over the trunk. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197905PMC
December 2019

Incidence and treatment costs of severe bacterial infections among people who inject heroin: A cohort study in South London, England.

Drug Alcohol Depend 2020 May 6;212:108057. Epub 2020 May 6.

National Addiction Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, 4 Windsor Walk, Camberwell, London SE5 8AF, UK; South London and Maudsley NHS Foundation Trust, Monks Orchard Road Beckenham, London BR3 3BX, UK; Centre for Epidemiology and Biostatistics, Melbourne School of Global and Population Health, Level 3, 207 Bouverie Street, The University of Melbourne Victoria 3010 Australia; RAND Europe, Westbrook Centre, Milton Road, Cambridge CB4 1YG, UK.

Background: People who inject drugs often get bacterial infections. Few longitudinal studies have reported the incidence and treatment costs of these infections.

Methods: For a cohort of 2335 people who inject heroin entering treatment for drug dependence between 2006 and 2017 in London, England, we reported the rates of hospitalisation or death with primary causes of cutaneous abscess, cellulitis, phlebitis, septicaemia, osteomyelitis, septic arthritis, endocarditis, or necrotising fasciitis. Read More

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http://dx.doi.org/10.1016/j.drugalcdep.2020.108057DOI Listing

necrotizing fasciitis following elective surgery.

Med Mycol Case Rep 2020 Jun 20;28:39-41. Epub 2020 Apr 20.

Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA, USA.

Necrotizing fasciitis is a potentially fatal soft tissue infection that requires prompt clinical suspicion, pharmacological and surgical interventions. Bacterial pathogens, such as beta-hemolytic streptococcus and , are the main etiology of necrotizing fasciitis, however, rare cases caused by fungal pathogens, such as , have been reported following trauma. Here, we present the first case of necrotizing fasciitis following an elective surgical procedure in an immunocompetent adult. Read More

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http://dx.doi.org/10.1016/j.mmcr.2020.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214761PMC

Traditional herbal treatment induced bilateral amputation of the feet in a five-year-old child: A case report.

Int J Surg Case Rep 2020 11;70:110-114. Epub 2020 May 11.

Medical Faculty of Universitas Airlangga, Jl. Prof. Dr Moestopo 6-8 Surabaya, 60115, Indonesia.

Introduction: Bilateral gangrene of both legs in a child is a rare condition which may lead to sepsis when improperly treated. In certain rare cases, autoamputation may occur instead. We report a case of bilateral symmetrical autoamputation of the feet following necrotizing fasciitis after a fall injury which was treated with herbal medicine in a five-year-old child. Read More

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http://dx.doi.org/10.1016/j.ijscr.2020.04.062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229236PMC

Predictors of fatal outcome after severe necrotizing fasciitis: Retrospective analysis in a tertiary hospital for 20 years.

J Orthop Sci 2020 May 12. Epub 2020 May 12.

Department of Orthopaedic Surgery, School of Medicine, Jichi Medical University, Shimotsuke, Japan.

Background: Prognostic factors for fatal outcomes of patients with necrotizing fasciitis remain unclear.

Methods: We retrospectively analyzed data of patients with necrotizing fasciitis from January 1998 to July 2019 using our hospital's medical database. Clinical characteristics of patients who died during hospitalization or had been discharged were evaluated. Read More

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http://dx.doi.org/10.1016/j.jos.2020.04.007DOI Listing

Anaerobic infection simulating necrotizing fasciitis, induced by liposuction for surgical treatment of siliconoma.

Dermatol Ther 2020 May 14:e13583. Epub 2020 May 14.

Department of Dermatology, Spedali Civili, University of Brescia, Brescia, Italy.

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http://dx.doi.org/10.1111/dth.13583DOI Listing

Necrotizing fasciitis in haematological patients: a different scenario.

Ann Hematol 2020 May 12. Epub 2020 May 12.

Infectious Diseases Department, Hospital Universitari Vall d'Hebron, Vall d'Hebron Institut de Recerca, Universitat Autònoma de Barcelona, Department of Medicine, Pg. Vall d'Hebron 119-129, 08035, Barcelona, Spain.

To describe and compare the characteristics of necrotizing fasciitis (NF) in patients with and without haematological malignancy. All adult patients diagnosed with NF and treated at our hospital were included (January 2010-March 2019). Diagnosis was based on intraoperative findings or consistent clinical/radiological characteristics, and patients were classified as group A (with haematological malignancy) or group B (without haematological malignancy). Read More

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http://dx.doi.org/10.1007/s00277-020-04061-yDOI Listing

Cervical Necrotizing Fasciitis After Surgery of a Mandibular Fracture.

J Craniofac Surg 2020 May 8. Epub 2020 May 8.

Department of Oral and Maxillofacial Surgery, Tehran University of Medical Sciences, School of Dentistry, Tehran, Iran.

Introduction: Cervical necrotizing fasciitis (CNF) is a rapid progressing and potentially fatal infection of connective tissues that spreads along the fascial planes. It commonly develops from odontogenic sources. In this article, the authors present a case of CNF which was developed after open reduction and internal fixation (ORIF) of a mandibular fracture. Read More

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http://dx.doi.org/10.1097/SCS.0000000000006471DOI Listing

Fournier's gangrene: a review of reconstructive options.

Cent European J Urol 2020 31;73(1):74-79. Epub 2019 Dec 31.

Department of Plastic, Reconstructive and Esthetic Surgery and Burn Unit, Centro Hospitalar de São João, Porto, Portugal.

Introduction: Fournier's gangrene is a rapidly progressive necrotizing fasciitis of the genital and perineal tissues with a high mortality rate. Early diagnosis and treatment with fluid resuscitation, surgical debridement and wide-spectrum antibiotics are essential in the management of Fournier's gangrene. After primary treatment, reconstructive surgery is often necessary for coverage of soft-tissue defects. Read More

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http://dx.doi.org/10.5173/ceju.2020.0060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203772PMC
December 2019

Group A streptococcus AdcR regulon participates in bacterial defense against host-mediated zinc sequestration and contributes to virulence.

Infect Immun 2020 May 11. Epub 2020 May 11.

Center for Molecular and Translational Human Infectious Diseases Research, Houston Methodist Research Institute, and Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, TX, 77030, USA

Colonization by pathogenic bacteria depends on their ability to overcome host nutritional defenses and acquire nutrients. The human pathogen group A streptococcus (GAS) encounters host defense factor calprotectin (CP) during infection. CP inhibits GAS growth by imposing zinc (Zn) limitation. Read More

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http://dx.doi.org/10.1128/IAI.00097-20DOI Listing

Carbapenemases: Transforming into a Yet More Dangerous Menace.

Biomolecules 2020 May 6;10(5). Epub 2020 May 6.

Center for Applied Biotechnology Studies, Department of Biological Science, California State University Fullerton, Fullerton, CA 92831, USA.

is a common cause of serious nosocomial infections. Although community-acquired infections are observed, the vast majority occur in people with preexisting comorbidities. emerged as a problematic pathogen in the 1980s when an increase in virulence, difficulty in treatment due to drug resistance, and opportunities for infection turned it into one of the most important threats to human health. Read More

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http://dx.doi.org/10.3390/biom10050720DOI Listing

Classifications in Brief: Laboratory Risk Indicator for Necrotizing Fasciitis Score.

Clin Orthop Relat Res 2020 May 5. Epub 2020 May 5.

E. H. Sato, C. M. Domes, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.

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http://dx.doi.org/10.1097/CORR.0000000000001291DOI Listing

A 16-year Longitudinal Cohort Study of Incidence and Bacteriology of Necrotising Fasciitis in England.

World J Surg 2020 May 7. Epub 2020 May 7.

Health Informatics and Surgery, University Hospitals Birmingham NHS Foundation Trust, Birmingham, B15 2GW, UK.

Background: Necrotising fasciitis (NF) is a rapidly progressive, destructive soft tissue infection with high mortality. The primary aim of this study was to evaluate the incidence and mortality of NF amongst patients admitted to English National Health Service (NHS) hospitals. The secondary aims included the identification of risk factors for mortality and causative pathogens. Read More

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http://dx.doi.org/10.1007/s00268-020-05559-2DOI Listing

Independent Predictors of Mortality for Aeromonas Necrotizing Fasciitis of Limbs: An 18-year Retrospective Study.

Sci Rep 2020 May 7;10(1):7716. Epub 2020 May 7.

Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.

Necrotizing fasciitis (NF) of the limbs caused by Aeromonas species is an extremely rare and life-threatening skin and soft tissue infection. The purpose of this study was to evaluate the specific characteristics and the independent predictors of mortality in patients with Aeromonas NF. Sixty-eight patients were retrospectively reviewed over an 18-year period. Read More

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http://dx.doi.org/10.1038/s41598-020-64741-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205975PMC

Klebsiella pneumoniae necrotizing fasciitis on the upper lip in a patient with uncontrolled diabetes.

Arch Craniofac Surg 2020 Apr 20;21(2):127-131. Epub 2020 Apr 20.

Department of Plastic and Reconstructive Surgery, Kangdong Sacred Heart Hospital, Seoul, Korea.

A 60-year-old woman with a history of diabetes mellitus and chronic renal failure was admitted to the hospital with severe pain in the upper lip, which began 4 days prior to admission, accompanied by a bullous lesion and suspected cellulitis in the upper lip. Immediately after admission, as the patient´s general condition worsened, tests revealed a non-ST elevated myocardial infarction, septic embolism of the lung, as well as septic shock. Her upper lip suddenly presented a gangrenous and necrotic change, which the tissue and blood culture confirmed to be a Klebsiella pneumoniae infection. Read More

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http://dx.doi.org/10.7181/acfs.2019.00696DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7206462PMC

Necrotizing fasciitis of the upper back presenting with left shoulder pain.

Clin Pract 2020 Mar 27;10(1):1218. Epub 2020 Apr 27.

Department of Radiology, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh Campus, Selangor, Malaysia.

Necrotizing fasciitis is a severe and progressive infection of deep soft tissues which results in destruction of the fascia and overlying subcutaneous fat. We report a case of a 45-year-old diabetic gentleman who initially presented with left shoulder pain, which was treated symptomatically. Upon representation, he had fever and the pain extended to his left upper back. Read More

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http://dx.doi.org/10.4081/cp.2020.1218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196934PMC

A report of probable paroxysmal sympathetic hyperactivity syndrome in a patient with necrotizing fasciitis.

Can J Anaesth 2020 May 5. Epub 2020 May 5.

Department of Emergency & Critical Care Medicine, Island Health Authority, Vancouver, BC, Canada.

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http://dx.doi.org/10.1007/s12630-020-01694-5DOI Listing

Upper extremity exertional rhabdomyolysis: MR imaging findings in four cases.

Radiol Case Rep 2020 Jun 20;15(6):789-794. Epub 2020 Apr 20.

Division of Musculoskeletal Radiology, Department of Radiology, Duke University, Medical Center, 2301 Erwin Road, Durham, NC 27705, USA.

While uncommon, exertional-induced rhabdomyolysis is an important diagnostic consideration when encountering hyperintensity within one or more muscles on fluid sensitive sequences in conjunction with signal abnormality in the overlying superficial fascia and subcutaneous fat. The clinical history of recent extreme exercise helps distinguish this disorder from other possible diagnoses, such as cellulitis, necrotizing fasciitis, compartment syndrome, inflammatory processes and diabetic myonecrosis. Patients diagnosed with severe exertional induced rhabdomyolysis often require hospital admission for intravenous hydration and serial laboratory monitoring due to the potential risk of acute renal failure. Read More

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http://dx.doi.org/10.1016/j.radcr.2020.03.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178327PMC

Delay in the Referral of Pregnant Patients with Fascial Spaces Infection: A Cross-Sectional Observational Study from Khartoum Teaching Dental Hospital, Sudan.

J Maxillofac Oral Surg 2020 Jun 9;19(2):298-301. Epub 2019 Mar 9.

Oral and Maxillofacial Surgery, Nile college, P. O. Box 3354, Riyadh, 11211 Kingdom of Saudi Arabia.

Purpose: Odontogenic infections have the potential to develop rapidly into deep-space infections and compromise the airway. This problem is aggravated by pregnancy because of the physiological changes. This study aimed to determine the causes of referral delay for pregnant patients presenting with fascial space infections. Read More

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http://dx.doi.org/10.1007/s12663-019-01206-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176762PMC

Necrotizing fasciitis of the neck with pharyngeal fistula: An unusual case presentation.

Int J Infect Dis 2020 Apr 25;96:196-198. Epub 2020 Apr 25.

Department of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Tianjin, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ijid.2020.04.050DOI Listing

Fournier gangrene: pictorial review.

Abdom Radiol (NY) 2020 Apr 27. Epub 2020 Apr 27.

Department of Medical Imaging, The Ottawa Hospital, Ottawa, Ontario, Canada.

Fournier gangrene is an emergency condition that is associated with a high mortality rate. It is defined as a rapidly progressing infective necrotizing fasciitis of the perineal, perianal, and genital regions. Early diagnosis, broad-spectrum antibiotic coverage, and adequate surgical debridement are crucial and lead to better prognosis and patient survival. Read More

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http://dx.doi.org/10.1007/s00261-020-02549-9DOI Listing

Necrotising fasciitis.

BMJ 2020 Apr 27;369:m1428. Epub 2020 Apr 27.

Port Macquarie Base Hospital, Port Macquarie, New South Wales, Australia.

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http://dx.doi.org/10.1136/bmj.m1428DOI Listing

Global emergence of environmental non-O1/O139 Vibrio cholerae infections linked with climate change: a neglected research field?

Environ Microbiol 2020 Apr 26. Epub 2020 Apr 26.

Centre for Environment, Fisheries and Aquaculture Science, CEFAS, Weymouth, UK.

The bacterium Vibrio cholerae is a natural inhabitant of aquatic ecosystems across the planet. V. cholerae serogroups O1 and O139 are responsible for cholera outbreaks in developing countries accounting for 3-5 million infections worldwide and 28. Read More

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http://dx.doi.org/10.1111/1462-2920.15040DOI Listing

Successful Mastectomy and Chemotherapy in a Patient with Breast Cancer and Active Generalized Pyoderma Gangrenosum.

Wounds 2020 Apr;32(4):E19-E22

Department of Dermatology and Wound care and Hyperbaric Medicine, Oregon Health and Science University, Portland, OR.

Introduction: Pyoderma gangrenosum (PG) is a rare, ulcerating neutrophilic dermatosis often associated with inflammatory bowel disease, rheumatoid arthritis, and myeloproliferative disorders. The classic description of PG includes irregularly shaped ulcers with undermined edges with a gun-metal gray or violaceous hue. The etiology remains unclear but appears to be related to genetically predisposed dysregulation of the innate immune system. Read More

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Lactoferrin: A Critical Mediator of Both Host Immune Response and Antimicrobial Activity in Response to Streptococcal Infections.

ACS Infect Dis 2020 May 7. Epub 2020 May 7.

Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, United States.

Streptococcal species are Gram-positive bacteria responsible for a variety of disease outcomes including pneumonia, meningitis, endocarditis, erysipelas, necrotizing fasciitis, periodontitis, skin and soft tissue infections, chorioamnionitis, premature rupture of membranes, preterm birth, and neonatal sepsis. In response to streptococcal infections, the host innate immune system deploys a repertoire of antimicrobial and immune modulating molecules. One important molecule that is produced in response to streptococcal infections is lactoferrin. Read More

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http://dx.doi.org/10.1021/acsinfecdis.0c00050DOI Listing

Sonographic exploration for fascial exploration (SEFE) in necrotizing fasciitis: a case report.

Ultrasound J 2020 Apr 22;12(1):24. Epub 2020 Apr 22.

WellSpan York Hospital Emergency Medicine Residency Program, WellSpan York Hospital, York, PA, USA.

Background: Necrotizing skin and soft tissue infections are life-threatening conditions. Reliance on gas in tissue planes leads to worsened outcomes in patients with non-gas forming types of necrotizing fasciitis (NF).

Case Presentation: We present a case of Group A Strep (GAS) necrotizing fasciitis, which was identified at bedside with point-of-care ultrasound (US) including an area of subfascial fluid. Read More

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http://dx.doi.org/10.1186/s13089-020-00168-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176767PMC

Necrotizing Fasciitis due to Candida Infection after Thyroid Surgery.

Authors:
Mustafa Aslıer

Turk Arch Otorhinolaryngol 2020 Mar 26;58(1):56-60. Epub 2020 Mar 26.

Department of Otorhinolaryngology Head and Neck Surgery, Sancaktepe Şehit Prof. Dr. İlhan Varank Training and Research Hospital, İstanbul, Turkey.

Surgical site infections (SSIs) after thyroidectomy are very rare as it is a clean case surgery, even the patterns for the use of prophylactic antibiotics is disputable. Cutaneous and subcutaneous tissue infections are the most common type of SSIs that develop due to the contamination of the skin flora pathogens during surgical incision. We report the case of a patient who, unlike the reports in the literature, developed necrotizing fasciitis due to Candida infection after total thyroidectomy. Read More

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http://dx.doi.org/10.5152/tao.2020.4927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162601PMC

Necrotizing Fasciitis Causing Acute Compartment Syndrome after Radial Artery Catheterization.

Eur J Case Rep Intern Med 2020 27;7(4):001525. Epub 2020 Feb 27.

Serviço de Medicina Interna, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.

Necrotizing fasciitis is a rare but potentially fatal infection involving the subcutaneous tissue and fascia with the development of necrosis of these structures. Acute compartment syndrome occurs when increased pressure within a closed muscle compartment compromises the circulation and function of the tissues within that space. We report the case of a male patient who was admitted to the intensive care unit for the management of urosepsis due to an acute obstructive pyelonephritis complicated by cardiopulmonary arrest. Read More

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http://dx.doi.org/10.12890/2020_001525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162573PMC
February 2020

Serial change of neutrophil extracellular traps in tracheal aspirate of patients with acute respiratory distress syndrome: report of three cases.

J Intensive Care 2020 10;8:25. Epub 2020 Apr 10.

1Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.

Background: Neutrophil extracellular traps (NETs) are fibrous structures released from activated neutrophils. NET formation has been reported to be associated with acute respiratory distress syndrome (ARDS). However, there are no reports dealing with serial changes of NET formation in tracheal aspirate of ARDS patients. Read More

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http://dx.doi.org/10.1186/s40560-020-00444-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7149861PMC

[Clinical analysis of 61 cases of deep neck infection].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2020 04;55(4):358-362

Department of Otorhinolaryngology Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai 264000, China.

To explore the clinical experience in care for deep neck infection (DNI) and to analyze the factors influencing surgical treatment outcome. A retrospective analysis was conducted on 61 patients with DNI admitted to the Department of Otorhinolaryngology Head and Neck Surgery of Yantai Yuhuangding Hospital from March 2013 to April 2019, including 33 males and 28 females, aged from 6 months to 81 years with a median age of 49 years. Patients were divided into two groups, 31 cases with localized infection (neck abscess) in Group A and 30 cases with diffuse infection (neck necrotizing fasciitis) in Group B. Read More

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http://dx.doi.org/10.3760/cma.j.cn115330-20190911-00574DOI Listing

[: skin and soft tissue infections].

Rev Med Suisse 2020 Apr;16(690):732-738

Service des maladies infectieuses, HUG, 1211 Genève.

Skin infections are a frequent cause of consultation, yet the diagnosis can be challenging for physicians. Microbiological documentation is rare, and empiric antibiotic regimens should cover the most commonly identified bacteria, i.e. Read More

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[Necrotizing fasciitis-a surgical emergency].

Chirurg 2020 May;91(5):437-446

Hochschulzentrum für Plastische‑, Ästhetische, Hand- und Wiederherstellungschirurgie, Universitätsklinikum Regensburg, Regensburg, Deutschland.

Necrotizing fasciitis is a fulminant and potentially life-threatening infection of the skin and soft tissue. It is usually caused by a combination of different bacteria and is often due to assumed minor trauma. Clinically, only relatively insignificant skin changes are initially present, such as blistering or erythema. Read More

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http://dx.doi.org/10.1007/s00104-020-01161-3DOI Listing

Monomicrobial Fournier's gangrene caused by Panton-Valentine leukocidin-negative methicillin-susceptible Staphylococcus aureus ST8 in Japan: A case report.

Intern Med 2020 Apr 16. Epub 2020 Apr 16.

Department of Endocrinology and Metabolism, Kashiwa Municipal Hospital, Japan.

Methicillin-resistant Staphylococcus aureus USA300, belonging to sequence type (ST) 8, is a rare cause of necrotizing fasciitis in the USA. We herein report a case of monomicrobial Fournier's gangrene caused by an ST8, methicillin-susceptible Staphylococcus aureus (designated ksw1). Whole-genome sequencing and analyses for virulence determinants revealed that, unlike USA300, ksw1 lacked virulence genes, such as Panton-Valentine leukocidin and SCCmec, while harboring the toxic shock syndrome toxin-1 gene. Read More

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http://dx.doi.org/10.2169/internalmedicine.4334-19DOI Listing

False vocal cord perforation with abscess treated by negative pressure wound therapy.

SAGE Open Med Case Rep 2020 2;8:2050313X20915415. Epub 2020 Apr 2.

Department of Otolaryngology-Head & Neck Surgery, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.

Perforation of the larynx is very rare but may result in severe airway complications that include pneumothorax, pneumonia, mediastinitis, and retropharyngeal abscess. If conservative treatment fails, aggressive treatments including reconstructive surgery with pedicle flap are considered. Negative pressure wound therapy has been used for large skin defects, necrotizing fasciitis, pharyngocutaneous fistula, stoma dehiscence, osteoradionecrosis of the mandible, chyle fistula, flap failure, and lymphangioma in the field of head and neck surgery. Read More

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http://dx.doi.org/10.1177/2050313X20915415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139174PMC

Treatment of children with Hyperbaric Oxygenation (HBOT): an Europe-wide survey.

Minerva Pediatr 2020 Apr 9. Epub 2020 Apr 9.

Department for Intensive Care Medicine, Medical Faculty, RWTH Aachen University, Aachen, Germany.

Background: Hyperbaric oxygenation therapy (HBOT) is used as emergency treatment for decompression sickness, gas embolism, carbon monoxide intoxication, necrotizing fasciitis. There is low evidence and little clinical knowledge about treating children with HBOT.

Methods: We sent an internet-based questionnaire to HBO centers in Europe to gain information about their experience with children and HBOT. Read More

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http://dx.doi.org/10.23736/S0026-4946.20.05741-2DOI Listing

Self-inflicted human bite followed by hand necrotizing fasciitis in an adult with Down syndrome.

Clin Case Rep 2020 Apr 5;8(4):699-701. Epub 2020 Feb 5.

Okayama Saiseikai General Hospital Okayama Japan.

Adults with Down syndrome are more prone to develop intellectual, physical, and psychological disorders than their pediatric counterparts. It is pertinent to prevent the occurrence of severe complications in these patients. This case demonstrates the importance of support, regular follow-up, and wound management in self-care of adults with Down syndrome. Read More

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http://dx.doi.org/10.1002/ccr3.2701DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141720PMC

Retrograde nailing, trabecular metal implant and use of bone marrow aspirate concentrate after failed ankle joint replacement.

Foot Ankle Surg 2020 Mar 13. Epub 2020 Mar 13.

Consultant Foot and Ankle Surgeon, Diakonhjemmet Hospital, Oslo, Norway. Electronic address:

Background: Ankle fusion after removal of alloplasty is known to be a procedure with a high potential for non-unions and poor function, especially tibio-talo-calcaneal fusion. We wanted to review our results after using a novel method for the procedure, combining retrograde nailing with a trabecular metal implant and bone marrow aspirate concentration applied in an ostoconductive pad in addition to autologous bone grafting.

Materials And Methods: Retrospective review of a patient series, with some prospectively registered data. Read More

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http://dx.doi.org/10.1016/j.fas.2020.03.003DOI Listing

Septicemia, necrotizing fasciitis, and peritonitis due to Vibrio vulnificus treated with early use of polymyxin B hemoperfusion in a patient undergoing CAPD: a case report.

BMC Nephrol 2020 Apr 9;21(1):127. Epub 2020 Apr 9.

Department of Internal Medicine, College of Medicine, Institute of Kidney Disease Research, Yonsei University College of Medicine, Seoul, Republic of Korea.

Background: Vibrio vulnificus infection is a rare but fatal foodborne illness. Here, we report a case of Vibrio vulnificus peritonitis followed by severe septicemia in a patient undergoing continuous ambulatory peritoneal dialysis (CAPD) who was treated with hemoperfusion using polymyxin B immobilized fiber.

Case Presentation: A 63-year-old man undergoing CAPD was admitted to the emergency room due to general weakness, fever, and abdominal pain with hazy dialysate. Read More

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http://dx.doi.org/10.1186/s12882-020-01772-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146884PMC