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    1 OF 86

    Group A Streptococcal bacteraemia. Experience at King Fahad Medical City in Riyadh, Saudi Arabia.
    Saudi Med J 2017 Oct;38(10):1034-1037
    Pediatric Infectious Diseases Section, Children's Specialized Hospital, King Fahad Medical City, Riyadh, Kingdom of Saudi Arabia. E-mail.
    Objectives: To identify clinical presentation, predisposing factors, and the outcome in patients with Group A Streptococcal bacteremia. Methods: This is a retrospective study of 33 pediatric and adult patients with Streptococcus pyogenes bacteremia, admitted at King Fahad Medical City, Riyadh, Kingdom of Saudi Arabia from 2007 to 2015. Results: Thirty-three patient records, documenting bacteremia with group A beta-hemolytic streptococcus, were reviewed. Read More

    Cellulitis in aged persons: a neglected infection in the literature.
    Pan Afr Med J 2017 30;27:160. Epub 2017 Jun 30.
    Department of Internal Medicine, Sahloul Hospital, Faculty of Medicine of Sousse, Sousse, Tunisia.
    Cellulitis is a frequent soft tissue and skin infection. The lower limbs are affected in 70 to 80% of cases. Cellulitis in aged persons is not yet well described in literature. Read More

    Treatment of Staphylococcus aureus Infections.
    Curr Top Microbiol Immunol 2017 Sep 13. Epub 2017 Sep 13.
    Department of Pediatrics, The University of Chicago, 5841 S. Maryland Ave., MC6054, Chicago, IL, 60637, USA.
    Staphylococcus aureus, although generally identified as a commensal, is also a common cause of human bacterial infections, including of the skin and other soft tissues, bones, bloodstream, and respiratory tract. The history of S. aureus treatment is marked by the development of resistance to each new class of antistaphylococcal antimicrobial drugs, including the penicillins, sulfonamides, tetracyclines, glycopeptides, and others, complicating therapy. Read More

    Presenting features of extremity necrotizing fasciitis in the pediatric patient: a case-control analysis.
    J Pediatr Orthop B 2017 Sep 4. Epub 2017 Sep 4.
    aDepartment of Orthopedics, Rady Children's Hospital and Health Center bDepartment of Orthopaedic Surgery, University of California, San Diego, California, USA.
    This analysis sought to develop a tool for early differentiation between pediatric necrotizing fasciitis (NF) of the extremity and more benign infection. All diagnoses of extremity NF, cellulitis, and abscess from a single institution from 2009 to 2015 were included. Vitals and laboratory values were compared between cohorts using analysis of variance and decision tree analysis. Read More

    A case of bisphosphonate-related osteonecrosis of the jaw with a particularly unfavourable course: a case report.
    J Korean Assoc Oral Maxillofac Surg 2017 Aug 24;43(4):272-275. Epub 2017 Aug 24.
    Department of Medicine, Surgery and Neurosciences, ENT Clinic, University of Siena, Siena, Italy.
    Bisphosphonates are drugs used to treat osteoclast-mediated bone resorption, including osteoporosis, Paget disease, multiple myeloma, cancer-related osteolysis, and malignant hypercalcemia. The use of these drugs has increased in recent years as have their complications, especially bisphosphonate-related osteonecrosis of the jaw (BRONJ), which more frequently affects the mandible. Here we report a case of BRONJ with a particularly unfavorable course due to cervical inflammation that developed into necrotizing fasciitis, followed by multiorgan involvement leading to septic shock and death. Read More

    Magnetic Resonance Imaging of Musculoskeletal Emergencies.
    Semin Ultrasound CT MR 2017 Aug 5;38(4):439-452. Epub 2017 Apr 5.
    Department of Radiology, Baystate Medical Center, University of Massachusetts, Springfield, MA.
    Musculoskeletal trauma and infections are commonly encountered in the emergency department. Magnetic resonance imaging (MRI) is rarely employed in true emergencies and most musculoskeletal studies can be deferred to the outpatient setting. This article seeks to address the urgent conditions in which MRI can play a role in diagnosis, management, and treatment. Read More

    Negative Pressure Wound Therapy for a Giant Wound Secondary to Malignancy-induced Necrotizing Fasciitis: Case Report and Review of the Literature.
    Wounds 2017 Aug;29(8):E55-E60
    Division of Plastic & Reconstructive Surgery, McMaster University, Hamilton, Ontario, Canada.
    Background: Necrotizing fasciitis (NF) is a life-threatening condition in which rapid diagnosis, debridement of nonviable tissue, and broad-spectrum antibiotics are critical to effective treatment. The debridement required can be extensive, resulting in large wounds that can sometimes be covered with split-thickness skin grafts (STSGs) with the help of negative pressure wound therapy (NPWT), or vacuum-assisted closure, to decrease the wound size.

    Case Report: The authors report a rare case of NF due to malignancy-associated bowel perforation with a giant lower extremity wound secondary to debridement that involved 20% of the total body surface area (TBSA) in a 64-year-old, previously healthy, nonsmoking man. Read More

    Using negative pressure therapy for improving skin graft taking on genital area defects following Fournier gangrene.
    Turk J Urol 2017 Sep 1;43(3):366-370. Epub 2017 Aug 1.
    Clinic of Plastic Surgery, Antalya Training and Research Hospital, Antalya, Turkey.
    Objective: Fournier's gangrene is an infective necrotizing fasciitis of the perineal, genital and perianal regions. Treatment includes aggressive surgical debridement that often results in extensive loss of genital skin. Skin grafts may be used for reconstruction but skin grafting of the male genitalia is diffucult because the penis and scrotum are mobile and deformable. Read More

    Cervical Necrotizing Fasciitis of Odontogenic Origin and Hyperbaric Oxygen Therapy.
    J Craniofac Surg 2017 Aug 28. Epub 2017 Aug 28.
    *Department of Otorhinolaryngology, Cerrahpasa Medical Faculty †Department of Undersea and Hyperbaric Medicine ‡Department of Plastic and Reconstructive, Surgery, Istanbul University, Istanbul, Turkey.
    Necrotizing fasciitis (NF) is an infection of the soft tissues pathology with high mortality that spreads through the fascial planes and rarely seen in head and neck region. The cause of infection is often odontogenic problems. Broad-spectrum antibiotics, surgical debridement, and hyperbaric oxygen therapy (HBO) are important for the treatment of disease. Read More

    Risk factors for mortality in fournier's gangrene in a general hospital: use of simplified founier gangrene severe index score (SFGSI).
    Int Braz J Urol 2017 Aug 30;43. Epub 2017 Aug 30.
    Faculdade de Medicina da Universidade Estadual de Ciências da Saúde de Alagoas (UNCISAL), Maceió, AL, Brasil.
    Objective: To evaluate risk factors for mortality in patients with Fournier's gangrene (FG), with emphasis in the Simplified Fournier Gangrene Severe Index Score (SFGSI).

    Materials And Methods: This was a cross-sectional study that was carried out from January 2010 to December 2014, with 124 patients treated for FG in a General Hospital. Several clinical and laboratory variables, including SFGSI, were evaluated and correlated with mortality through univariate analysis and logistic regression. Read More

    Mesh erosion to urinary bladder causing fistulation to abdominal wall resulting in necrotizing fasciitis: A case report of late complication of incisional hernia.
    Int J Surg Case Rep 2017 Aug 18;39:185-187. Epub 2017 Aug 18.
    Department of Surgery, United Christian Hospital, Hong Kong Address of United Christian Hospital: 130, Hip Wo Street, Kwun Tong, Kowloon, Hong Kong.
    Introduction: Incisional hernia is not an uncommon complication after abdominal operation, and laparoscopic ventral hernia repair with mesh is commonly performed nowadays. It is thought to have less complication compare to the traditional open repair, yet late complication is still observed occasionally and can be disastrous.

    Case Report: We hereby report a case of abdominal wall necrotizing fasciitis 21 months after laparoscopic incisional hernia repair in lower midline with dual mesh, due to mesh migration and erosion into urinary bladder, resulting in fistulation between bladder and abdominal wall. Read More

    The obesity paradox in patients with severe soft tissue infections.
    Am J Surg 2017 Sep 9;214(3):385-389. Epub 2016 Jul 9.
    Center for Surgery and Public Health, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School and Harvard T. H. Chan School of Public Heath, Boston, MA, USA; Trauma, Burn and Surgical Critical Care Division, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address:
    Background: The "obesity paradox" has been demonstrated in chronic diseases but not in acute surgery. We sought to determine whether obesity is associated with improved outcomes in patients with severe soft tissue infections (SSTIs).

    Methods: The 2006 to 2010 Nationwide Inpatient Sample was used to identify adult patients with SSTIs. Read More

    Presentation and outcomes of necrotizing soft tissue infections.
    Int J Gen Med 2017 31;10:215-220. Epub 2017 Jul 31.
    Division of Emergency Medicine, Faculty of Medicine, London Health Sciences Centre, Western University, London, ON, Canada.
    Background: Necrotizing soft tissue infections (NSTIs) are aggressive infections associated with significant morbidity, including amputation and organ failure, and high mortality. The rapid progression and significant risk of morbidity and mortality associated with NSTIs makes quick diagnosis and treatment critical. The objective of this study was to determine the presentation of patients diagnosed with NSTIs and their in-hospital outcomes. Read More

    Necrotizing fasciitis following venomous snakebites in a tertiary hospital of southwest Taiwan.
    Int J Infect Dis 2017 Aug 12;63:30-36. Epub 2017 Aug 12.
    Department of Orthopaedic Surgery, Chia-Yi Chang Gung Memorial Hospita, Taiwan, Republic of China; College of Medicine, Chang Gung University at Taoyuan, Taiwan, Republic of China.
    Background: Necrotizing fasciitis following venomous snakebites is uncommon. The purpose of this study was to describe the initial clinical features of necrotizing fasciitis after snakebites, and to identify the risk factors for patients with cellulitis who later developed necrotizing fasciitis.

    Methods: Sixteen patients with surgically confirmed necrotizing fasciitis and 25 patients diagnosed with cellulitis following snakebites were retrospectively reviewed over a 6-year period. Read More

    RocA is an accessory protein to the virulence-regulating CovR/S two-component system in the group A Streptococcus.
    Infect Immun 2017 Aug 14. Epub 2017 Aug 14.
    Department of Microbiology & Immunology, University of Nevada, Reno School of Medicine, Reno, Nevada, USA.
    Regulating gene expression during infection is critical to the ability of pathogens to circumvent the immune response and cause disease. This is true for the group A Streptococcus (GAS), a pathogen that causes both invasive (e.g. Read More

    An aggressive and fatal craniofacial group A Streptococcus infection resulting from a minimally displaced orbital floor fracture.
    Int J Oral Maxillofac Surg 2017 Aug 10. Epub 2017 Aug 10.
    Attending Surgeon, Department of Surgery, R Adams Cowley Shock Trauma Center, University of Maryland Medical Center, Baltimore, MD, USA.
    While sharp, penetrating trauma is often associated with group A Streptococcus (GAS) infections and subsequent necrotizing fasciitis (NF) and streptococcal toxic shock syndrome (STSS), there are scant reports in the oral and maxillofacial surgery literature regarding blunt, non-penetrating trauma in association with these conditions. With a clinical course that initially appears relatively benign following blunt trauma, NF can progress swiftly through the fascial planes and may quickly become life-threatening if the oral and maxillofacial surgeon fails to recognize some of the critical pathognomonic signs. The case of a 64-year-old female who suffered a ground-level mechanical fall with a minimally displaced lateral orbital wall fracture is reported here. Read More

    [Plastic reconstruction of external genitalia after Fournier's gangrene].
    Urologe A 2017 Aug 11. Epub 2017 Aug 11.
    Abteilung für Urologie und Kinderurologie, Zentralkrankenhaus Bozen, Lorenz Böhler Straße 5, 39100, Bozen, Italien.
    Fournier's gangrene is a rapidly progressing necrotizing fasciitis restricted to the perineal and genital regions. Although rare, it is an acute life-threatening disease, requiring rapid radical surgical debridement and antibiotic treatment, resulting in large soft tissue defects. Various reconstructive methods for defect coverage are applied to satisfactorily reconstitute functionality and esthetics. Read More

    Alcohol use disorder increases the risk of necrotizing fasciitis: A nationwide retrospective cohort study.
    Medicine (Baltimore) 2017 Aug;96(32):e7509
    aDepartment of Emergency Medicine, China Medical University Hospital bSchool of Medicine, College of Medicine, China Medical University cDepartment of Health Services Administration, China Medical University dCollege of Medicine, China Medical University eManagement Office for Health Data, China Medical University Hospital, Taichung, Taiwan.
    This nationwide retrospective cohort study determined the association between alcohol use disorder (AUD) and the risk of necrotizing fasciitis (NF).This study used health insurance claims data of 52,212 in-patients with AUD and 208,848 controls randomly frequency-matched by age and sex at a 1:4 ratio. The AUD cohort included patients newly diagnosed with AUD between January 1, 2000 and December 31, 2008. Read More

    Comparison of vacuum-assisted closure therapy and debridement with primer surgical closure for fournier's gangrene treatment: 10 years' experience of a single centre.
    Int Braz J Urol 2017 Aug 8;43. Epub 2017 Aug 8.
    Department of Urology, Recep Tayyip Erdogan University, Rize, Turkey.
    Objective: Fournier's gangrene is a type of necrotizing soft tissue infection of the perineal, genital and perianal region that has a rapidly progressive and potentially fatal course. In the present study, our goal was to compare the patients submitted to surgical debridement for Fournier Gangrene with Vacuum-asisted Closure (VAC) and without VAC therapy after debridement.

    Materials And Methods: We retrospectively analyzed 313 patients underwent surgical debridement for FG in our hospital. Read More

    Group A streptococcal M protein activates the NLRP3 inflammasome.
    Nat Microbiol 2017 Aug 7. Epub 2017 Aug 7.
    Department of Pediatrics, University of California, San Diego, La Jolla, CA, 92093, USA.
    Group A Streptococcus (GAS) is among the top ten causes of infection-related mortality in humans. M protein is the most abundant GAS surface protein, and M1 serotype GAS strains are associated with invasive infections, including necrotizing fasciitis and toxic shock syndrome. Here, we report that released, soluble M1 protein triggers programmed cell death in macrophages (Mϕ). Read More

    Comparison of intubation and tracheotomy in patients with deep neck infection.
    Eur Arch Otorhinolaryngol 2017 Aug 5. Epub 2017 Aug 5.
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Helsinki and Helsinki University Hospital, PO Box 263, 00029, Helsinki, Finland.
    Possible airway compromise further complicates treatment of deep neck infections (DNI). Airway management is crucial, but factors affecting the method of choice are unclear. We retrospectively evaluated adult DNIs in a single tertiary center covering 10 years, with special attention on airway management. Read More

    Evaluation and Management of Necrotizing Soft Tissue Infections.
    Infect Dis Clin North Am 2017 Sep;31(3):497-511
    Clinical Epidemiology Section, Department of Critical Care Medicine, National Institutes of Health Clinical Center, 10 Center Drive 10/2C145, Bethesda, MD 20892, USA. Electronic address:
    Despite advances in antibiotic and surgical management and supportive care for necrotizing soft tissue infections, morbidity and mortality remain substantial. Although there are clinical practice guidelines in place, there still remains much variability in choice and duration of antibiotic therapy, time to initial surgical debridement, and use of adjuvant medical therapies. This article offers an overview of necrotizing soft tissue infections with a focus on current diagnostic and treatment modalities. Read More

    A Red Blood Cell Membrane-Camouflaged Nanoparticle Counteracts Streptolysin O-Mediated Virulence Phenotypes of Invasive Group A Streptococcus.
    Front Pharmacol 2017 18;8:477. Epub 2017 Jul 18.
    Biomedical Sciences Graduate Program, University of California, San Diego, La JollaCA, United States.
    Group A Streptococcus (GAS), an important human-specific Gram-positive bacterial pathogen, is associated with a broad spectrum of disease, ranging from mild superficial infections such as pharyngitis and impetigo, to serious invasive infections including necrotizing fasciitis and streptococcal toxic shock syndrome. The GAS pore-forming streptolysin O (SLO) is a well characterized virulence factor produced by nearly all GAS clinical isolates. High level expression of SLO is epidemiologically linked to intercontinental dissemination of hypervirulent clonotypes and poor clinical outcomes. Read More

    Necrotising fasciitis in a patient treated with FOLFIRI-aflibercept for colorectal cancer: a case report.
    Ann R Coll Surg Engl 2017 Aug 3:e1-e2. Epub 2017 Aug 3.
    Medical oncologist at Puerta de Hierro Majadahonda University Hospital.
    Anti-angiogenics have become an important part of the treatment of several types of tumours such as ovarian, breast, lung and colorectal cancer. Necrotising fasciitis has been reported with bevacizumab but no cases have been reported with aflibercept, ramucirumab or regorafenib in patients with colorectal cancer. Necrotising fasciitis is a rare complication affecting one in 5000 bevacizumab users. Read More

    Necrotizing Fasciitis: A Rare Complication of Acute Necrotizing Pancreatitis.
    J Clin Diagn Res 2017 Jun 1;11(6):PD05-PD06. Epub 2017 Jun 1.
    Professor, Department of Surgery, Command Hospital Air force, Bangalore, Karnataka, India.
    Necrotizing pancreatitis occurs in 10 to 25% of patients requiring hospital admission for acute pancreatitis and carries a high mortality rate. Necrotizing pancreatitis can cause a spectrum of complications. However, we report an extremely rare complication of necrotizing pancreatitis: necrotizing fasciitis of the abdominal wall. Read More

    Fournier's Gangrene: Lessons Learned from Multimodal and Multidisciplinary Management of Perineal Necrotizing Fasciitis.
    Front Surg 2017 10;4:36. Epub 2017 Jul 10.
    Fourth Surgical Department, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
    Background: Fournier's gangrene (FG) is a rapidly evolving necrotizing fasciitis of the perineum and the genital area, the scrotum as it most commonly affects man in the vast majority of cases. It is polymicrobial in origin, due to the synergistic action of anaerobes and aerobes and has a very high mortality. There are many predisposing factors including diabetes mellitus, alcoholism, immunosuppression, renal, and hepatic disease. Read More

    Post-partum streptococcal toxic shock syndrome associated with necrotizing fasciitis.
    IDCases 2017 27;9:91-94. Epub 2017 Jun 27.
    Department of Obstetrics & Gynaecology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kota Bharu, Kelantan, Malaysia.
    We report a fatal case of post-partum streptococcal toxic shock syndrome in a patient who was previously healthy and had presented to the emergency department with an extensive blistering ecchymotic lesions over her right buttock and thigh associated with severe pain. The pregnancy had been uncomplicated, and the mode of delivery had been spontaneous vaginal delivery with an episiotomy. She was found to have septicemic shock requiring high inotropic support. Read More

    Infectious Complications of Circumcision and Their Prevention.
    Eur Urol Focus 2016 Oct 19;2(4):453-459. Epub 2016 Feb 19.
    Departments of Pediatrics and Medicine, Georgetown University School of Medicine, Washington, DC, USA. Electronic address:
    Context: A growing body of evidence supports the health benefits of circumcision, but the occurrence of infectious complications is of concern.

    Objective: To review literature presenting past data and studies of infectious complications of circumcision and their prevention.

    Evidence Acquisition: A literature search was conducted of the Cochrane Library, Embase, Turning Research into Practice, PubMed, and Medline databases from their inception through June 25, 2015. Read More

    Epidemiology and distribution of 10 superantigens among invasive Streptococcus pyogenes disease in Germany from 2009 to 2014.
    PLoS One 2017 18;12(7):e0180757. Epub 2017 Jul 18.
    Institute of Medical Microbiology and National Reference Center for Streptococci, University Hospital (RWTH), Aachen, Germany.
    A nationwide laboratory-based surveillance study of invasive S. pyogenes infections was conducted in Germany. Invasive isolates (n = 719) were obtained between 2009 and 2014. Read More

    Postoperative Pyoderma Gangrenosum in Children: The Case Report of a 13-Year-Old Boy With Pyoderma Gangrenosum After Hip Reconstruction Surgery and a Review of the Literature.
    J Pediatr Orthop 2017 Sep;37(6):e379-e383
    *Department of Children's Orthopedics, Hospital for Children Munich-Schwabing, Munich †BG Trauma Center Murnau, Murnau, Germany.
    Background: Postoperative pyoderma gangrenosum (PG) is a neutrophilic dermatosis and pathergic reaction at surgical sites. Reports of children with postoperative PG are rare in the literature.

    Methods: We report the case of a 13-year-old boy without any known preexisting illnesses, who developed severe systemic response and wound deterioration after elective hip reconstruction surgery. Read More

    A Randomized Controlled Trial on the Outcome in Comparing an Alginate Silver Dressing With a Conventional Treatment of a Necrotizing Fasciitis Wound.
    Int J Low Extrem Wounds 2017 Jun 17;16(2):108-113. Epub 2017 Apr 17.
    1 Department of Surgery, Faculty of Medicine, Chiang Mai University, Thailand.
    Necrotizing fasciitis (NF) is a high morbidity and mortality disease and also demands high economic resources. The standard treatment of NF is surgical debridement and proper dressing for wound bed preparation. The efficacy of silver alginate dressing can inhibit the growth of microorganisms and keep the environment clean for wound bed preparation. Read More

    Cervical-thoracic necrotizing fasciitis of odontogenic origin in a diabetic patient: a case report.
    Gen Dent 2017 Jul-Aug;65(4):25-29
    Necrotizing fasciitis (NF) is a severe bacterial infection with rapid and aggressive progression. The infection generally affects individuals with comorbid conditions that lead to immunologic and microvascular deficiencies. It is characterized by necrosis of tissues, mainly in the extremities, trunk, and perineum, and is rarely found in the head and neck. Read More

    Early clinical manifestations of vibrio necrotising fasciitis: a case series.
    Singapore Med J 2017 07 6. Epub 2017 Jul 6.
    Department of Orthopaedic Surgery, National University Hospital, Singapore.
    We present five patients with vibrio necrotising fasciitis, a lethal and disabling disease. Among our patients, two had a history of exposure to either warm seawater or raw/live seafood, three had underlying chronic liver disease, and four presented with hypotension and fever. There were three deaths and four patients required intensive care unit stay. Read More

    Candida pararugosa: First Reported Bloodstream Infection in an Adult.
    Cureus 2017 May 29;9(5):e1283. Epub 2017 May 29.
    Clinical Pathology, Wake Forest Baptist Medical Center.
    Candida pararugosa is a yeast that has been previously isolated in various human specimens. The first reported isolation was from human feces in 1998, with subsequent reports of positive cultures from the oral cavity where it was thought to represent colonization rather than true infection. Though it has been isolated from other human sites, its clinical significance and manifestations are poorly characterized. Read More

    Biomarkers of Necrotising Soft Tissue Infections Aspects of the Innate Immune Response.
    Dan Med J 2017 Jul;64(7)
    Necrotising soft tissue infection (NSTI) is a life-threatening and rapidly progressing bacterial infection involving one or more layers of the soft tissue compartments causing necrosis. The amputation and mortality rates remain high despite increased focus on the patients. Timely treatment, including surgical intervention, reduces the risk of severe disability and death. Read More

    Necrotising fasciitis as atypical presentation of infection with emerging Neisseria meningitidis serogroup W (MenW) clonal complex 11, the Netherlands, March 2017.
    Euro Surveill 2017 Jun;22(23)
    Centre for Infectious Diseases Control, National Institute for Public Health and the Environment, Bilthoven, the Netherlands.
    In March 2017, a patient with necrotising fasciitis caused by Neisseria meningitidis serogroup W (MenW) clonal complex 11 was diagnosed in the Netherlands. Unusual and severe presentations of MenW infections are common in the current European epidemic. In the Netherlands, the incidence of MenW infections increased 10-fold, from an average of 0. Read More

    Lower-Extremity Infections Caused by Serratia marcescens A Report of Three Cases and a Literature Review.
    J Am Podiatr Med Assoc 2017 May;107(3):231-239
    Serratia marcescens is a ubiquitous, facultatively anaerobic, gram-negative bacillus that has been cited to cause infection in immunocompromised populations. In the literature, S marcescens infections of the lower extremity have presented as granulomatous ulceration, abscess, bullous cellulitis, and necrotizing fasciitis. Herein we present a series of three cases of lower-extremity infections in which S marcescens was the sole or a contributing pathogen. Read More

    Hyperbaric oxygen may only be optional in head and neck necrotizing fasciitis: a retrospective analysis of 43 cases and review of the literature.
    Infect Dis (Lond) 2017 Nov - Dec;49(11-12):792-798. Epub 2017 Jun 23.
    b Department of Otorhinolaryngology Head and Neck Surgery , Regionshospitalet Holstebro HEV , Holstebro , Denmark.
    Background: Necrotizing fasciitis in the head and neck (NF-HN) is a rare and potentially life-threatening condition. The use of hyperbaric oxygen therapy (HBOT) in the acute regimen is disputed and there is a lack of evidence of therapeutic effect. This study aims to describe a retrospective cohort of patients with NF-HN and investigate the use of HBOT and consequences thereof. Read More

    Necrotizing fasciitis attended in the Emergency Department in a tertiary Hospital: Evaluation of the LRINEC scale.
    Rev Esp Cir Ortop Traumatol 2017 Jul - Aug;61(4):265-272. Epub 2017 Jun 20.
    Servicio de Infecciones, Hospital Clínic de Barcelona, Barcelona, España.
    Aim: To describe mortality and complications of patients seen in the emergency room, diagnosed with necrotizing soft tissue infection (NSTI) and the correlation of such complications with the Laboratory Risk Indicator for Necrotizing fasciitis scale (LRINEC).

    Methods: Retrospective observational study including patients with a diagnosis of NSTI in the emergency room of a tertiary hospital over 7 years. The results are shown as median, interquartile range and absolute range for quantitative variables. Read More

    Emergency incarcerated obturator hernia repair with biologic mesh in a male patient after ipsilateral hip disarticulation: A case report.
    Int J Surg Case Rep 2017 8;37:41-44. Epub 2017 Jun 8.
    Alabama College of Osteopathic Medicine, Class of 2018, 445 Health Science Blvd., Dothan, AL 36303, USA.
    Introduction: An obturator hernia is an uncommon form of abdominal hernia that is difficult to diagnose due to its non-distinct presentation. This case investigates an emergency treatment of an obturator hernia presenting in a patient with an ipsilateral hip disarticulation in a 266-bed community hospital.

    Presentation Of Case: A 53-year old man with a history of a left hip disarticulation 3-weeks prior presented to the emergency department with fever, nausea, vomiting, and diarrhea for the past 5-days. Read More

    A Fatal Aortic Arch Rupture Due to Descending Necrotizing Mediastinitis in a 24-year-old Woman.
    Vasc Endovascular Surg 2017 Aug 15;51(6):408-412. Epub 2017 Jun 15.
    6 Intensive Care Unit, University Hospital of Nice, Nice, France.
    Descending necrotizing mediastinitis (DNM) is a life-threatening disease which often develops from a purulent infection of the oral cavity and is associated with high rates of mortality. Here we report the case of a young patient who died from an aortic arch rupture in context of DNM developed from an odontogenic infection caused by Prevotella buccae. Based on the current knowledge on this very rare vascular complication, we discuss factors that may have contributed to this fatal issue and future issues to optimize care provided to patients. Read More

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