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    4135 results match your criteria Necrotizing Fasciitis

    1 OF 83

    Retroperitoneal Necrotizing Fasciitis Masquerading as Perianal Abscess - Rare and Perilous.
    Cureus 2017 Jan 17;9(1):e982. Epub 2017 Jan 17.
    General Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.
    Necrotizing fasciitis is one of the uncommon presentations of a rapidly spreading subcutaneous tissue infection. Although the actual cause is unclear in many cases, most of them are due to the rapid proliferation of microorganisms. Retroperitoneal necrotizing fasciitis is extremely rare. Read More

    Early Diagnosis and Surgical Treatment for Necrotizing Fasciitis: A Multicenter Study.
    Front Surg 2017 7;4. Epub 2017 Feb 7.
    3rd Department of Surgery, Medical School, National and Kapodistrian University of Athens, Attikon University Hospital , Athens , Greece.
    Background: Necrotizing fasciitis (NF) is a group of relatively rare infections, usually caused by two or more pathogens. It affects the skin and subcutaneous tissues of lower and upper limbs, perineal area (Fournier's gangrene), and the abdominal wall. Early diagnosis and aggressive surgical management are of high significance for the management of this potentially lethal disease. Read More

    The spectrum and outcome of surgical sepsis in Pietermaritzburg, South Africa.
    S Afr Med J 2017 Jan 30;107(2):134-136. Epub 2017 Jan 30.
    Department of Surgery, Pietermaritzburg Hospital Complex and School of Clinical Medicine, College of Health Sciences, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.
    Background: Sepsis is a leading cause of morbidity and mortality worldwide, and the incidence appears to be increasing. In the resource-limited environment in low- and middle-income countries, the management of surgical sepsis (SS) continues to represent a significant portion of the workload for most general surgeons.

    Objective: To describe the spectrum of SS seen at a busy emergency department, and categorise the outcomes. Read More

    Negative pressure wound therapy: An update.
    Chin J Traumatol 2017 Jan 25. Epub 2017 Jan 25.
    Plastic Surgery Center, Faculty of Medicine, Mansoura University, Mansoura 35516, Egypt. Electronic address:
    Purpose: To get the maximum benefit of vacuum-assisted closure (VAC) in the management of acute and chronic wounds without abuse or misuse.

    Methods: Fourty one patients were included in the study. Among them, 9 patients had chronic wounds and the rest 32 patients had acute wounds. Read More

    Reconstruction of an Anterior Cervical Necrotizing Fasciitis Defect Using a Biodegradable Polyurethane Dermal Substitute.
    Eplasty 2017 25;17:e3. Epub 2017 Jan 25.
    Adult Burn Centre, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
    Introduction: Although we have previously described the use of a novel polyurethane biodegradable dermal substitute in the reconstruction of 20 free flap donor sites, and extensive cutaneous defects, including a large area of exposed calvarium secondary to burn injury, our experience with this material now extends to 35 free flap donor site reconstructions and 13 major or complex burns. Methods: The polyurethane material (NovoSorb BTM; PolyNovo Biomaterials Pty Ltd, Port Melbourne, Victoria, Australia) was recently employed in another complex wound scenario, implanted into a large anterior cervical cutaneous and soft-tissue defect remaining after serial radical debridement for necrotizing fasciitis. Results: Implantation, integration, delamination, and split-skin graft application proceeded without complication, mirroring our previous experience in other wounds (including major burns). Read More

    Contributing Factors for Complications and Outcomes in Patients With Snakebite: Experience in a Medical Center in Southern Taiwan.
    Ann Plast Surg 2017 Feb 14. Epub 2017 Feb 14.
    From the *Division of Plastic and Reconstructive Surgery, Department of Surgery, Kaohsiung Veterans General Hospital, Kaohsiung; and †National Yang-Ming University, Taipei, Taiwan, Republic of China.
    Objectives: Snakebite usually results in various complications, such as significant soft tissue damage, infection, hematological, and neurological deficit. Surgical intervention, usually, is indicated in patients with tissue necrosis, infection, and compartment syndrome. To identify the contributing factors for complications and outcomes in different patients with snakebite so that outcomes can be evaluated and treatment of such patients can be initiated at the earliest. Read More

    Challenging Airway Secondary to Purpura Fulminans With Face and Neck Bullae in a Premature Infant: A Case Report.
    A A Case Rep 2017 Feb;8(4):70-71
    From the Departments of Pediatric Anesthesiology and Pediatric Plastic Surgery, Children's Memorial Hermann Hospital, McGovern Medical School, Houston, Texas.
    A former 25-week-old neonate presented at 34 weeks postconceptual age with necrotizing fasciitis and purpura fulminans because of Group B Streptococcus infection. He was septic and coagulopathic when he was intubated, and the endotracheal tube was secured with adhesives. When he subsequently developed large purpuric, bullous lesions on the face and neck, he presented to the operating room for excision and debridement of his facial lesions. Read More

    Application of a Silicone Sheet in Negative-Pressure Wound Therapy to Treat an Abdominal Wall Defect after Necrotizing Fasciitis.
    Arch Plast Surg 2017 Jan 20;44(1):76-79. Epub 2017 Jan 20.
    Department of Plastic and Reconstructive Surgery, Soonchunhyang University College of Medicine, Cheonan, Korea.
    Necrotizing fasciitis (NF) is an aggressive soft-tissue infection involving the deep fascia and is characterized by extensive deterioration of the surrounding tissue. Immediate diagnosis and intensive treatment, including debridement and systemic antibiotics, represent the most important factors influencing the survival of NF patients. In this report, we present a case of NF in the abdomen due to an infection caused by a perforated small bowel after abdominal liposuction. Read More

    A case report of primary necrotising fasciitis of the breast: A rare but deadly entity requiring rapid surgical management.
    Int J Surg Case Rep 2017 Jan 23;31:221-224. Epub 2017 Jan 23.
    Blacktown Hospital, NSW, Australia.
    Introduction: Necrotising fasciitis of the breast is a rare entity with very few cases reported in the literature. It is rapidly progressive and can lead to sepsis and multi-organ failure without prompt medical and surgical management.

    Presentation Of Case: We describe a case of a non-diabetic 23-year-old female with primary necrotising fasciitis of the right breast. Read More

    [Dentogene Focus as a Rare Cause of Necrotizing Fasciitis].
    Dtsch Med Wochenschr 2017 Feb 10;142(3):212-215. Epub 2017 Feb 10.
    Abteilung für Diagnostische und Interventionelle Radiologie, Universitätsklinikum Tübingen.
    History and clinical findings We elaborate the case of a 72-year-old patient who presented with a painful swelling of the lower jaw in the emergency unit. Investigations and diagnosis In the clinical examination and the CT scan, a widespread cervical emphysema was found which raised suspicion for the presence of a necrotizing fasciitis of the head and neck due to aerogenic infection. Close spatial vicinity to the teeth of the left upper and lower jaw was present, so that the necrotizing fasciitis was assumed to be odontogenic. Read More

    Monomicrobial Klebsiella pneumoniae Necrotizing Fasciitis With Liver Abscess: A Case Report and Literature Review.
    Ann Plast Surg 2017 Feb 8. Epub 2017 Feb 8.
    From the *Division of Plastic and Reconstructive Surgery, Department of Surgery, Taipei Veterans General Hospital; and †Institute of Clinical Medicine, School of Medicine, National Yang-Ming University, Taiwan, Republic of China.
    Background: Necrotizing fasciitis is one of the most life-threatening soft tissue infections and usually follows a major or minor trauma. Published reports regarding single microorganism liver abscess caused by Klebsiella pneumoniae in Taiwan indicate a septic metastasis rate about 12%. Although a hematogenous origin of necrotizing fasciitis from a liver abscess is rare in Taiwan, it remains possible in our clinical practice. Read More

    Association between cytokine response, the LRINEC score and outcome in patients with necrotising soft tissue infection: a multicentre, prospective study.
    Sci Rep 2017 Feb 8;7:42179. Epub 2017 Feb 8.
    Center for Infectious Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
    Early assessment of necrotising soft tissue infection (NSTI) is challenging. Analysis of inflammatory markers could provide important information about disease severity and guide decision making. For this purpose, we investigated the association between cytokine levels and the Laboratory Risk Indicator for Necrotising Fasciitis (LRINEC)-score, disease severity and mortality in NSTI patients. Read More

    Pancreatic Fistula Extending into the Thigh Caused by the Rupture of an Intraductal Papillary Mucinous Adenoma of the Pancreas.
    Intern Med 2017 1;56(3):307-313. Epub 2017 Feb 1.
    Department of Gastroenterology, Kitasato University School of Medicine, Japan.
    We herein report the first case of a pancreatic fistula extending into the thigh caused by the rupture of an intraductal papillary mucinous neoplasm (IPMN) of the pancreas. An 80-year-old man was suspected to have necrotizing fasciitis because of right femoral pain. Computed tomography showed fluid retention from the pancreatic head to the right iliopsoas muscle and an IPMN at the pancreatic head. Read More

    Cervical necrotizing fasciitis and acute mediastinitis of odontogenic origin: A case series.
    J Clin Exp Dent 2017 Jan 1;9(1):e150-e152. Epub 2017 Jan 1.
    Maxillofacial Surgeon. Hospital Universitario Virgen de las nieves, Granada, Spain.
    Necrotising fasciitis (NF) is an uncommon infection. Early signs and symptoms include fever, severe pain and swelling, and redness at the wound site. Moreover, fulminant evolution and high mortality rate are typical of this pathology. Read More

    Estimation of the capacity of emergency surgery in Konya: Nine-year multicenter study.
    Ulus Cerrahi Derg 2016 27;32(4):252-255. Epub 2016 Oct 27.
    Department of General Surgery, Başkent University Konya Training and Research Hospital, Konya, Turkey.
    Objective: Although the number of surgical emergencies continues to increase, comprehensive data on emergency surgical admissions are scarce. The aim of this multicenter study was to evaluate the causes, management, and outcomes of the general surgical emergencies in the city of Konya, Turkey.

    Material And Methods: The relevant details of the cases admitted and considered to be general surgical emergencies in Konya over a nine-year period (January 2003-January 2012) were analyzed. Read More

    Bilateral thigh methicillin-resistant Staphylococcus aureus necrotising fasciitis in a man with newly diagnosed Human Immunodeficiency Virus (HIV).
    BMJ Case Rep 2017 Jan 30;2017. Epub 2017 Jan 30.
    Department of Pulmonary, Critical Care, and Sleep Disorders Medicine, University of Louisville School of Medicine, Louisville, Kentucky, USA.
    Methicillin-resistant Staphylococcus aureus (MRSA) necrotising fasciitis (NF) is rare and constitutes a medical and surgical emergency. We report a case of a 53-year-old man with type-2 diabetes mellitus and newly diagnosed HIV infection who presented with 1 week of progressively worsening bilateral sharp thigh pain. On presentation, he was febrile, tachycardic and had bilateral thigh erythema and mild tenderness without open wounds. Read More

    Necrotizing Fasciitis of the Abdominal Wall in a Premature Infant: A Case Study.
    Neonatal Netw 2017 Jan;36(1):26-31
    We present a first report of necrotizing fasciitis of the abdominal wall in a 23-day-of-age, former 32-week-gestation premature infant. She was successfully treated with antibiotics without the need for initial debridement. After reviewing the etiology of necrotizing fasciitis, we discuss the unique aspects of this case, including the noninvasive approach to initial treatment, which we consider significantly contributed to her survival. Read More

    [Alternative Methods of Local Therapy for Complicated Periocular Infections - Two Case Reports].
    Klin Monbl Augenheilkd 2017 Jan 30;234(1):36-39. Epub 2017 Jan 30.
    Augenklinik und Poliklinik, Universitätsmedizin der Johannes Gutenberg-Universität Mainz.
    Background Wounds of the eyelid can usually be cured with common surgical measures and the use of local antibiotics. Here we present two cases to demonstrate that biological debridement and negative pressure vacuum therapy (NPWT), two second line therapies, are effective and possibly superior alternatives to conventional, antibiotic-based approaches. Methodology and Result A persistent infectious wound of the upper eyelid after surgical debridement of necrotising fasciitis and an upper eyelid abscess with multiple purulent entry points, which was refractory to a five-week antibiotic regimen, were treated with biological debridement and NPWT. Read More

    [Peri-ocular Necrotising Fasciitis - Case Report and Overview].
    Klin Monbl Augenheilkd 2017 Jan 30;234(1):40-45. Epub 2017 Jan 30.
    Augenklinik, Universitätsklinikum Düsseldorf.
    Peri-ocular necrotising fasciitis is a very rare ophthalmological clinical picture and is potentially fatal. This disease is caused by bacterial infection of the fasciae, which rapidly spreads. The present article reports a typical case of the disease and gives an overview of the typical clinical signs and symptoms of peri-ocular necrotising fasciitis. Read More

    Are there any reasons to change our behavior in necrotizing fasciitis with the advent of new antibiotics?
    Curr Opin Infect Dis 2017 Apr;30(2):172-179
    Infectious Disease Unit, Cisanello Hospital, Pisa, Italy.
    Purpose Of Review: The treatment of necrotizing fasciitis requires a multifaceted approach, consisting of surgical source control with immediate surgical debridement along with life support, clinical monitoring, and antimicrobial therapy. Many drugs are now available for the treatment of this life-threatening infectious disease, and the purpose of this review is to provide the reader with an updated overview of the newest therapeutic options.

    Recent Findings: Because most necrotizing soft tissue infections are polymicrobial, broad-spectrum coverage is advisable. Read More

    Development of a DNA aptamer that binds specifically to group A Streptococcus serotype M3.
    Can J Microbiol 2017 Feb 14;63(2):160-168. Epub 2016 Oct 14.
    b GENEXIR Biopharma, a knowledge-based company at Pasteur Institute of Iran Health Technology Park, Tehran, Iran.
    Group A streptococcus (GAS) is an important Gram-positive pathogen that causes various human diseases ranging from peripheral lesions to invasive infections. The M protein is one of the main virulence factors present on the cell surface and is associated with invasive GAS infections. Compared with other M types, serotype M3 has a predominant role in lethal infections and demonstrates epidemic behaviors, including streptococcal toxic shock syndrome, bacteremia, and necrotizing fasciitis. Read More

    Diabetic Foot Infections: an Update in Diagnosis and Management.
    Curr Diab Rep 2017 Jan;17(1)
    First Department of Propaedeutic Internal Medicine, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, 33 Lakonias Street, 115 27, Athens, Greece.
    Foot infections are a common problem in patients with diabetes and a risk factor for limb amputation. They occur as a result of skin ulceration, which facilitates penetration of pathogens to deeper tissues. The diagnosis of infection is clinical. Read More

    Pyoderma gangrenosum following complex reconstruction of a large-scale lower limb defect by combined Parascapular and latissimus dorsi flap.
    J Surg Case Rep 2017 Jan 17;2017(1). Epub 2017 Jan 17.
    Department of Hand, Plastic, and Reconstructive Surgery, BG Trauma Center Ludwigshafen, Ruprecht-Karls-University of Heidelberg, Heidelberg, Germany.
    A female patient with a critical soft tissue defect after elective knee replacement surgery was transferred to our department for reconstruction. As wounds were rapidly progressing, necrotizing fasciitis was initially suspected but eventually ruled out by histopathological analysis. A 50 × 15 cm defect was then reconstructed by means of a combined Parascapular and latissimus dorsi flap before, a couple days later, the patient developed tender pustules and ulcers involving the flap as well as the donor site. Read More

    A rare case of a blood clot masquerading as a retained surgical drain.
    Ann Transl Med 2016 Dec;4(23):463
    Department of Orthopaedic Surgery, Tan Tock Seng Hospital, Singapore.
    Surgical drains are commonly used in surgery to reduce post-operative fluid collections. Whilst rare, a retained surgical drain may result in clinical complications and distress to the patient. A retained surgical drain is a potentially avoidable event and surgeons should be aware on how to confirm the presence of a retained surgical drain. Read More

    Instillation Therapy for the Treatment of Necrotizing Fasciitis: A Case Study.
    Cureus 2016 Dec 7;8(12):e917. Epub 2016 Dec 7.
    Cornerstone Surgical Specialists, High Point Regional, UNC Healthcare.
    A 57-year-old obese female with uncontrolled diabetes mellitus type I presented to the emergency department (ED) with the main complaint of worsening pain and redness in her right groin and inguinal regions. In the ED, a CT scan confirmed the likely presence of necrotizing fasciitis in the right groin and thigh. She was also found to be febrile and septic on admission. Read More

    Salvage therapy with intravenous fosfomycin plus ceftriaxone for necrotizing fasciitis caused by penicillin-nonsusceptible Streptococcus pneumoniae.
    J Microbiol Immunol Infect 2016 Dec 18. Epub 2016 Dec 18.
    Department of Internal Medicine, Chi Mei Medical Center, Tainan, Taiwan; Department of Health and Nutrition, Chia Nan University of Pharmacy and Science, Tainan, Taiwan. Electronic address:

    MDCT of hand and wrist infections: emphasis on compartmental anatomy.
    Clin Radiol 2017 Jan 6. Epub 2017 Jan 6.
    The Russell H. Morgan Department of Radiology & Radiological Science, The Johns Hopkins University School of Medicine, 601 North Wolfe Street, Baltimore, MD 21287, USA.
    Hand and wrist infections can present with a spectrum of manifestations ranging from cellulitis to deep-space collections. The various infectious processes can be categorised as superficial or deep infections based on their respective locations relative to the tendons. Superficial hand infections are located superficial to the tendons and are comprised of cellulitis, lymphangitis, paronychia, pulp-space infections, herpetic whitlow, and include volar as well as dorsal subcutaneous abscesses. Read More

    Necrotizing Fasciitis in Aesthetic Surgery: A Review of the Literature.
    Aesthetic Plast Surg 2017 Jan 7. Epub 2017 Jan 7.
    Dipartimento di Chirurgia Plastica Ricostruttiva, I.R.C.C.S. Policlinico San Donato, Università degli Studi di Milano, Via Morandi, 30, 20097, San Donato Milanese, Milan, Italy.
    Introduction: Necrotizing fasciitis (NF) is a rare, potentially fatal, infective complication that can occur after surgery. Diagnosis is still difficult and mainly based on clinical data. Only a prompt pharmacological and surgical therapy can avoid dramatic consequences. Read More

    Flaccid paralysis in an infant associated with a dirty wound and application of honey.
    BMJ Case Rep 2017 Jan 6;2017. Epub 2017 Jan 6.
    National Clinical Research Center, Kuala Lumpur, Wilayah Persekutuan, Malaysia.
    An infant, who was born preterm at 36 weeks, presented with fever and ulcer at umbilical region which progressed to necrotising fasciitis of anterior abdominal wall. He was treated with intravenous penicillin, intravenous cloxacillin and local application of medicated honey. Subsequently, he required wound debridement. Read More

    Rare Complication of Stomas: Peristomal Necrotizing Fasciitis.
    Wounds 2016 Dec;28(12):E47-E52
    Department of General Surgery, Faculty of Medicine, Istanbul University, Istanbul, Turkey.
    Introduction: A stoma formation is a frequently performed procedure in patients undergoing colorectal surgery. Although stoma formation is a simple process, it should be performed with caution. The aim of this study was to attract physicians' attention to this rare disease and also to identify the surgical and medical treatment options for peristomal necrotizing fasciitis as a rare complication. Read More

    Successful bypass operation for esophageal obstruction after acute esophageal necrosis: a case report.
    Surg Case Rep 2017 Dec 4;3(1). Epub 2017 Jan 4.
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.
    Background: Acute esophageal necrosis (AEN) is a rare clinical disorder. Esophageal stenosis or obstruction is one of severe complications, but there are a few reports about surgical treatments. In such a situation, it still remains controversial which to choose, esophagectomy or bypass operation. Read More

    Successful salvage and reconstruction of a finger threatened by Vibrio vulnificus necrotising fasciitis using fenestrated-type artificial dermis and three steps of topical negative pressure wound therapy.
    Int Wound J 2017 Jan 4. Epub 2017 Jan 4.
    Division of Plastic and Reconstructive Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
    Vibrio vulnificus can cause severe skin and soft tissue infection (SSTI). The pathogen is an opportunistic marine bacterium that is likely to infect patients with chronic liver disease, patients in an immunocompromised state, and those in end-stage renal disease. V. Read More

    Necrotizing fasciitis in a patient receiving tocilizumab for rheumatoid arthritis - Case report.
    Reumatol Clin 2016 Dec 29. Epub 2016 Dec 29.
    Rheumatology Department, Centro Hospitalar São João, Portugal.
    We present a case of necrotizing fasciitis in a 66-year-old Caucasian woman with rheumatoid arthritis receiving tocilizumab, and provide a review of published cases. The patient exhibited no systemic symptoms and discreet cutaneous inflammatory signals at presentation. She was successfully treated with broad-spectrum empiric antibiotic therapy and surgical debridement. Read More

    Pediatric Necrotizing Fasciitis: Restitutio Ad Integrum after Early Diagnosis and Aggressive Surgical Treatment.
    European J Pediatr Surg Rep 2016 Dec 28;4(1):34-36. Epub 2016 Nov 28.
    Department of Pediatric Surgery, University of Tübingen, Children's Hospital, Tuebingen, Germany.
    Necrotizing fasciitis (NF) is a severe, life-threatening infectious condition. Diagnosis is difficult due to unspecific symptoms yet crucial for favorable outcomes. We report a case of a 1 year old, previously healthy boy, where early suspicion of NF led to prompt aggressive therapy and consecutive restitutio ad integrum. Read More

    Impact of Intravenous Immunoglobulin on Survival in Necrotizing Fasciitis with Vasopressor-dependent Shock: A Propensity-Score Matched Analysis from 130 US Hospitals.
    Clin Infect Dis 2016 Dec 29. Epub 2016 Dec 29.
    1. Critical Care Medicine Department, National Institutes of Health Clinical Center, Bethesda, MD.
    Background: Shock frequently complicates necrotizing fasciitis (NF) caused by group A streptococcus (GAS) or Staphylococcus aureus (SA). Intravenous immunoglobulin (IVIG) is sometimes administered for presumptive toxic shock syndrome (TSS), but its frequency of use and efficacy are unclear.

    Methods: Adult patients with NF and vasopressor-dependent shock undergoing surgical debridement from 2010 to 2014 were identified at 130 U. Read More

    Fournier's gangrene during ACTH therapy.
    Brain Dev 2016 Dec 19. Epub 2016 Dec 19.
    Department of Pediatrics, Aichi Medical University, Japan.
    Fournier's gangrene is an infectious necrotizing fasciitis of the perineal, genital, or perianal regions and is uncommon in children. Adrenocorticotropic hormone (ACTH) is effective for the treatment of infantile spasms; however, suppression of immune function is one of the major adverse effects of this approach. We encountered a 2-month-old boy with infantile spasms that had been treated with ACTH and had developed complicating Fournier's gangrene. Read More

    A Case Review Series of Christiana Care Health System's Experience with Negative Pressure Wound Therapy Instillation.
    Cureus 2016 Nov 7;8(11):e865. Epub 2016 Nov 7.
    Director, Surgical Service Line Outcomes, Department of Surgery, Christiana Care Health System.
    Acute and chronic wounds afflict a multitude of patients to varying degrees. Wound care treatment modalities span the spectrum of technological advancement and with that differ greatly in cost. Negative pressure wound therapy (NPWT) can now be combined with instillation and dwell time (NPWTi-d). Read More

    Genome Analysis of Streptococcus pyogenes Associated with Pharyngitis and Skin Infections.
    PLoS One 2016 15;11(12):e0168177. Epub 2016 Dec 15.
    Department of Natural Sciences, Lebanese American University, School of Arts and Sciences, Byblos, Lebanon.
    Streptococcus pyogenes is a very important human pathogen, commonly associated with skin or throat infections but can also cause life-threatening situations including sepsis, streptococcal toxic shock syndrome, and necrotizing fasciitis. Various studies involving typing and molecular characterization of S. pyogenes have been published to date; however next-generation sequencing (NGS) studies provide a comprehensive collection of an organism's genetic variation. Read More

    Challenging Airway Secondary to Purpura Fulminans With Face and Neck Bullae in a Premature Infant.
    A A Case Rep 2016 Dec 9. Epub 2016 Dec 9.
    From the Departments of Pediatric Anesthesiology and Pediatric Plastic Surgery, Children's Memorial Hermann Hospital, McGovern Medical School, Houston, Texas.
    A former 25-week-old neonate presented at 34 weeks postconceptual age with necrotizing fasciitis and purpura fulminans because of Group B Streptococcus infection. He was septic and coagulopathic when he was intubated, and the endotracheal tube was secured with adhesives. When he subsequently developed large purpuric, bullous lesions on the face and neck, he presented to the operating room for excision and debridement of his facial lesions. Read More

    Successful treatment of a rare extended retroperitoneal necrotizing soft tissue infection caused by extended-spectrum beta-lactamase-producing Escherichia coli: A case report.
    Medicine (Baltimore) 2016 Dec;95(49):e5576
    aDepartment of Plastic Surgery and Burn bDepartment of Anti-infection cDepartment of Radiology, Peking University First Hospital, Beijing, People's Republic of China.
    Rationale: Retroperitoneal necrotizing soft tissue infection (NSTI) is a rare but life-threatening disease. Here, we present a case of extended retroperitoneal NSTI caused by extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli (E coli).

    Patient Concerns: The patient complained of progressive redness, swelling, and right flank pain for 10 days, extending to the scrotum for 1 day. Read More

    Evaluation of Factors Associated with Death in Patients with Necrotizing Fasciitis of the Abdominal Wall.
    Surg Infect (Larchmt) 2017 Feb/Mar;18(2):176-180. Epub 2016 Dec 8.
    1 Western Michigan University Homer Stryker MD School of Medicine , Kalamazoo, Michigan.
    Background: Necrotizing fasciitis (NF) is a rapidly progressing, life-threatening soft tissue infection. The prognostic factors associated with death from abdominal wall NF are not well understood.

    Methods: The medical records of 61 patients with abdominal wall NF were reviewed retrospectively. Read More

    Necrotic fasciitis of the lateral muscle group of the thigh following outside-in transobturatory tape procedure.
    Ceska Gynekol 2016 ;81(6):411-413
    Objective: Sling procedures are the preferred surgical treatment of stress urinary incontinence (SUI) due to their high success rate and low risk of complications.

    Design: Case report.

    Setting: Department of Obstetrics and Gynecology, Medical Faculty of Charles University and Faculty Hospital Hradec Kralove. Read More

    Complicated acute appendicitis presenting as a rapidly progressive soft tissue infection of the abdominal wall: a case report.
    J Med Case Rep 2016 Dec 1;10(1):331. Epub 2016 Dec 1.
    Department of Surgery, Clinic for Visceral and Thoracic Surgery, Kantonsspital Winterthur, Winterthur, Switzerland.
    Background: We report a case of a rare complication of acute appendicitis with perforation through the abdominal wall. The case points out that an intraabdominal origin should be considered in patients presenting with rapidly spreading soft tissue infections of the trunk.

    Case Presentation: A 58-year-old European woman presented to our hospital with a 1-week history of severe abdominal pain accompanied by rapidly spreading erythema and emphysema of the lower abdomen. Read More

    Fournier's gangrene of the penis in a 12-year-old patient secondary to phimosis.
    R I Med J (2013) 2016 Dec 1;99(12):45-46. Epub 2016 Dec 1.
    Hopital Universitaire de Mirebalais, Mirebalais, Haiti.
    We report a case of Fournier's gangrene in a 12-year-old boy from St. Boniface Hospital in Fond-des-Blancs, Haiti. Fournier's gangrene, a fulminant necrotizing fasciitis of the penis and scrotum, is a rare and life-threatening infection that requires hospitalization, broad-spectrum antibiotics, and surgical debridement. Read More

    Iron-Regulated Phospholipase C Activity Contributes to the Cytolytic Activity and Virulence of Acinetobacter baumannii.
    PLoS One 2016 22;11(11):e0167068. Epub 2016 Nov 22.
    Department of Microbiology, Miami University, Oxford, Ohio, United States of America.
    Acinetobacter baumannii is an opportunistic Gram-negative pathogen that causes a wide range of infections including pneumonia, septicemia, necrotizing fasciitis and severe wound and urinary tract infections. Analysis of A. baumannii representative strains grown in Chelex 100-treated medium for hemolytic activity demonstrated that this pathogen is increasingly hemolytic to sheep, human and horse erythrocytes, which interestingly contain increasing amounts of phosphatidylcholine in their membranes. Read More

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