101 results match your criteria Necrobiotic Xanthogranuloma


[Periocular Necrobiotic Xanthogranuloma with Mono- and Biclonal Gammopathy].

Klin Monbl Augenheilkd 2020 Jan 22;237(1):41-45. Epub 2020 Jan 22.

Augenklinik - Orbitazentrum, Bürgerhospital und Clementine Kinderhospital gGmbH, Frankfurt am Main.

Necrobiotic xanthogranuloma is a very rare disease with granulomatous lesions of the skin with possible association with paraproteinemia. We report two cases of orbital necrobiotic xanthogranuloma in patients with mono/biclonal gammopathy of undetermined significance. Both patients underwent successful conservative treatment. Read More

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http://dx.doi.org/10.1055/a-1032-8516DOI Listing
January 2020

Necrotic xanthogranuloma with disseminated annular lesions.

An Bras Dermatol 2020 Jan - Feb;95(1):117-119. Epub 2019 Dec 18.

Department of Dermatopathology, Hospital do Servidor Público Estadual (HSPE), São Paulo, SP, Brazil.

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http://dx.doi.org/10.1016/j.abd.2019.03.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058881PMC

Necrobiotic xanthogranuloma associated with smoldering multiple myeloma: satisfactory response to cyclophosphamide, dexamethasone, and thalidomide.

An Bras Dermatol 2019 Jul 29;94(3):337-340. Epub 2019 Jul 29.

Dermatology Service, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.

Necrobiotic xanthogranuloma is a rare chronic condition, belonging to the group C non-Langerhans cell histiocytoses, which is relevant due to the possibility of extracutaneous involvement and association with systemic diseases, particularly hematologic malignancies. The case reported here was only diagnosed after nine years of evolution and was associated with plasma cell dyscrasia. After treatment with cyclophosphamide, dexamethasone, and thalidomide, there was a reduction of cutaneous lesions and serum levels of monoclonal protein. Read More

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http://dx.doi.org/10.1590/abd1806-4841.20198500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668937PMC
July 2019
11 Reads

Necrobiotic Xanthogranuloma as the Presenting Manifestation of Smouldering Myeloma.

J Assoc Physicians India 2019 Mar;67(3):87-88

Department of Dermatology, All India Institute of Medical Sciences, New Delhi.

Necrobiotic xanthogranuloma is a rare dermatological manifestation of underlying hematological malignancies, in particular, when associated with paraproteinemia. These patients who are clinically symptomatic with chronic papules, nodules or plaques which demonstrate a histopathological pattern suggestive of extensive and frequently confluent areas of necrobiosis with granulomatous infiltration, warrant evaluation for an underlying monoclonal gammopathy. Read More

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March 2019
3 Reads

Non-infectious granulomatous dermatoses.

J Dtsch Dermatol Ges 2019 May;17(5):518-533

Department of Dermatology, Basel University Hospital, Basel, Switzerland.

Granulomatous dermatoses comprise a wide range of etiologically and clinically distinct skin diseases that share a common histology characterized by the accumulation of histiocytes include macrophages. While the pathogenesis of these disorders is not fully understood, the underlying mechanism is thought to involve a reaction pattern caused by an immunogenic stimulus. Antigen-presenting cells and the effect of various cytokines play a key role. Read More

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http://dx.doi.org/10.1111/ddg.13848DOI Listing
May 2019
6 Reads

[Necrobiotic xanthogranuloma misdiagnosed as a planocellular carcinoma].

Ugeskr Laeger 2019 Apr;181(14)

In this case report, an 89-year-old woman presented with a subcutaneous tumour in the orbital region. Fine needle aspiration showed no signs of malignancy. Following progressive tumour growth and cutaneous manifestation, an incisional biopsy was taken, which showed squamous cell carcinoma. Read More

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April 2019
3 Reads

Extrafacial necrobiotic xanthogranuloma and monoclonal gammopathy: two cases.

Int J Dermatol 2019 Jun 18;58(6):e112-e114. Epub 2019 Mar 18.

Dermatology Department, University Hospital of Bordeaux, Bordeaux, France.

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http://dx.doi.org/10.1111/ijd.14416DOI Listing
June 2019
4 Reads

Necrobiotic xanthogranuloma (without paraproteinemia) in a patient with Pelger-Huët anomaly.

Int J Dermatol 2019 Apr 26;58(4):E93-E94. Epub 2018 Dec 26.

Department of Dermatology and Radiotherapy, FMB-UNESP, Botucatu, São Paulo, Brazil.

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http://dx.doi.org/10.1111/ijd.14365DOI Listing
April 2019
3 Reads

Cutaneous adult xanthogranuloma with a small portion of BRAF mutated Langerhans cell histiocytosis populations: A case report and the review of published work.

J Dermatol 2019 Feb 7;46(2):161-165. Epub 2018 Dec 7.

Department of Dermatology, Gunma University Graduate School of Medicine, Maebashi, Japan.

Histiocytoses, including Langerhans cell histiocytosis (LCH), juvenile or adult xanthogranuloma (AXG) and Rosai-Dorfman disease (RDD), are rare disorders characterized by the proliferation of cells derived from monocyte/macrophage lineages. A few cases of LCH coexisting with xanthogranuloma or RDD have been reported. The etiology of these diseases remains unclear. Read More

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http://dx.doi.org/10.1111/1346-8138.14725DOI Listing
February 2019
41 Reads

A 9-year massive scrofuloderma of the scalp cured in 3 months.

Int J Dermatol 2019 Feb 2;58(2):e34-e36. Epub 2018 Nov 2.

Department of Dermatology, the Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.

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http://dx.doi.org/10.1111/ijd.14267DOI Listing
February 2019
2 Reads

Recurrent Bilateral Periorbital Swelling.

JAMA Ophthalmol 2018 12;136(12):1406-1407

University of California, Davis, Eye Center, Sacramento.

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http://archopht.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamaophthalmol.2018.1856DOI Listing
December 2018
3 Reads

Intravenous immunoglobulin for treatment of necrobiotic xanthogranuloma.

Dermatol Ther 2019 01 8;32(1):e12744. Epub 2018 Nov 8.

Division of Hematology, Oncology, and Transplantation, University of Minnesota, Minneapolis, MN.

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http://dx.doi.org/10.1111/dth.12744DOI Listing
January 2019
4 Reads
1.480 Impact Factor

Sustained clinical response after single course of rituximab as first-line monotherapy in adult-onset asthma and periocular xanthogranulomas syndrome associated with IgG4-related disease: A case report.

Medicine (Baltimore) 2018 Jun;97(26):e11143

Clinica Medica.

Rationale: IgG4-related disease (IgG4-RD) is an emerging immune-mediated disease characterized by multi-organ involvement and variable clinical behavior.

Patient Concerns: We describe the case of a 50-year-old woman affected by a rare variant of IgG4-RD, characterized by eyelid xanthelasmas, adult-onset asthma and salivary and lacrimal glands enlargement. Multiple lymphadenopathies and a pulmonary mass were present at initial evaluation. Read More

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http://Insights.ovid.com/crossref?an=00005792-201806290-0002
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http://dx.doi.org/10.1097/MD.0000000000011143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039602PMC
June 2018
29 Reads

Necrobiotic xanthogranuloma: a paraneoplastic skin lesion of haematological malignancies?

Eur J Dermatol 2018 Jun;28(3):384-386

Department of Vascular Medicine, INSERM CIC 1414, 35033 Rennes Cedex 9, France, Université de Rennes 1, INSERM CIC 1414, France.

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http://dx.doi.org/10.1684/ejd.2018.3256DOI Listing
June 2018
6 Reads

Necrobiotic Xanthogranuloma: A Cutaneous Manifestation of Monoclonal Gammopathy.

Actas Dermosifiliogr 2018 Nov 31;109(9):827. Epub 2018 Mar 31.

Unidad de Gestión Clínica de Dermatología Médico-Quirúrgica y Venereología, Complejo Hospitalario Universitario de Granada, Granada, España.

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http://dx.doi.org/10.1016/j.ad.2017.03.026DOI Listing
November 2018
1 Read

Necrobiotic xanthogranuloma: a 30-year single-center experience.

Ann Hematol 2018 Aug 22;97(8):1471-1479. Epub 2018 Mar 22.

Division of Hematology/Oncology, Mayo Clinic, 5777 E. Mayo Boulevard, Phoenix, AZ, 85054, USA.

To characterize the clinical features, associated disorders, and treatment of necrobiotic xanthogranuloma (NXG), a rare non-Langerhans cell histiocytosis, we conducted a retrospective review of pathologically confirmed NXG at Mayo Clinic Arizona from 1987 to June 2017. Data on clinical findings, laboratory findings, associated disorders, therapy, and response to therapy were extracted. Nineteen patients were identified. Read More

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http://dx.doi.org/10.1007/s00277-018-3301-1DOI Listing
August 2018
38 Reads
2.634 Impact Factor

Irregular yellow-brown plaques on the trunk and thighs.

Cutis 2018 Jan;101(1):12;15

Department of Dermatology, The University of Kansas, Kansas City, USA.

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January 2018
32 Reads

Necrobiotic xanthogranuloma associated with chronic lymphocytic leukemia.

Int J Dermatol 2018 Jun 27;57(6):719-720. Epub 2018 Feb 27.

Department of Dermatology, Venerology, and Allergology, University Medical Center, Ruprecht-Karl University, Heidelberg, Germany.

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http://dx.doi.org/10.1111/ijd.13951DOI Listing
June 2018
7 Reads

Granulomatous diseases: Kids are not just little people.

Clin Dermatol 2017 Nov - Dec;35(6):555-565. Epub 2017 Aug 4.

Department of Dermatology, University of Connecticut Health Center, Farmington, CT.

Granulomatous diseases represent a heterogeneous group of conditions characterized by histiocytic inflammation that affect patients of any age. These diseases differ widely in their pathogenesis and include infectious and noninfectious conditions. This review focuses on noninfectious granulomatous conditions, with particular emphasis on age-related differences in the onset, epidemiology, clinical manifestations, prognosis, and age-specific management of specific granulomatous disorders. Read More

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http://dx.doi.org/10.1016/j.clindermatol.2017.08.006DOI Listing
July 2018
10 Reads

Necrobiotic xanthogranuloma treated with lenalidomide.

Clin Exp Dermatol 2018 Apr 19;43(3):345-347. Epub 2017 Oct 19.

Dermatology Department, Kingston Hospital, London, UK.

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http://dx.doi.org/10.1111/ced.13293DOI Listing

Hepatobiliary and Pancreatic: Hepatic necrobiotic xanthogranuloma.

Authors:
B D Nguyen

J Gastroenterol Hepatol 2017 Oct;32(10):1667

Department of Radiology, Mayo Clinic, Scottsdale, Arizona, USA.

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http://dx.doi.org/10.1111/jgh.13858DOI Listing
October 2017
4 Reads

Xanthoma-like Skin Changes in an Elderly Woman with a Normal Lipid Profile.

Acta Dermatovenerol Croat 2017 Jul;25(2):167-169

Professor Joanna Maj, MD, PhD, Department and Clinic of Dermatology, Venereology and Allergology, Wroclaw Medical University, Chałubińskiego 1, PL-50-368 Wrocław, Poland;

Dear Editor, An 83-year-old woman developed yellow-brownish infiltrates, nodules, and tumors mimicking xanthomas, mostly involving the periorbital and chest area within three months (Figure 1). She had no abnormalities in serum cholesterol or triglycerides levels. A detailed laboratory analysis revealed the presence of mild monoclonal gammopathy with a presence of immunoglobulin G (IgG) kappa light chains; however, according to hematologist consultation, it did not require medical intervention. Read More

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July 2017
83 Reads

Rituximab Monotherapy Is Effective in Treating Orbital Necrobiotic Xanthogranuloma.

Ophthalmic Plast Reconstr Surg 2018 Jan/Feb;34(1):e24-e27

Orbital Oncology and Ophthalmic Plastic Surgery, Department of Plastic Surgery, Department of Lymphoma and Myeloma, Department of Pathology, and Department of Translational and Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, U.S.A.

The authors report a case of a patient with bilateral orbital necrobiotic xanthogranuloma and no associated systemic paraproteinemia. Orbital biopsy showed strong expression of CD20-positive cells. The patient was treated with systemic rituximab monotherapy, with excellent clinical response and marked regression of the orbital lesions on imaging. Read More

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http://dx.doi.org/10.1097/IOP.0000000000000988DOI Listing
February 2018
3 Reads

Necrobiotic xanthogranuloma associated with monoclonal gammopathy of unknown significance.

Med Clin (Barc) 2017 12 21;149(11):509-510. Epub 2017 Jul 21.

Unidad de Gestión Clínica de Medicina Interna, Hospital Universitario de Valme, Sevilla, España.

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http://dx.doi.org/10.1016/j.medcli.2017.06.015DOI Listing
December 2017
1 Read

[Facial manifestations of granulomatous diseases].

Authors:
F Butsch

Hautarzt 2017 Jul;68(7):542-547

Hautklinik und Poliklinik, Universitätsmedizin der Johannes Gutenberg-Universität Mainz KöR, Langenbeckstr. 1, 55131, Mainz, Deutschland.

Clinical manifestations of granulomatous diseases are a recurring challenge in everyday dermatological practice. Clinical presentation and histological patterns are variable, depending on the particular disease. Knowledge about the differential diagnosis of granulomatous changes in the face is of decisive importance for making a rational diagnosis and therapy considering the patient's well-being. Read More

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http://link.springer.com/10.1007/s00105-017-3994-4
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http://dx.doi.org/10.1007/s00105-017-3994-4DOI Listing
July 2017
1 Read

[Clinical and histological spectrum of palisaded granulomatous dermatitides : Granuloma annulare, necrobiosis lipoidica, rheumatoid nodules, and necrobiotic xanthogranuloma].

Hautarzt 2017 Jul;68(7):536-541

Hautklinik, Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Langenbeckstr. 1, 55131, Mainz, Deutschland.

The palisading granulomatous dermatitides comprise a group of different skin diseases with similar histomorphologic forms of granuloma in the skin. Histopathologically characteristic are areas in the reticular dermis and subcutaneous fat with degenerated bundles of collagen surrounded by histiocytes and multinucleate giant cells aligned in a palisade (necrobiotic granuloma). Within the center of palisaded granulomas, mucin or fibrin can be found. Read More

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http://dx.doi.org/10.1007/s00105-017-3995-3DOI Listing
July 2017
11 Reads

Leprosy clinically masquerading as necrobiotic xanthogranuloma: a histopathological surprise!

Int J Dermatol 2017 09 12;56(9):e184-e186. Epub 2017 Apr 12.

Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India.

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http://dx.doi.org/10.1111/ijd.13624DOI Listing
September 2017
14 Reads

Management of Uveitis and Scleritis in Necrobiotic Xanthogranuloma.

J Ocul Pharmacol Ther 2017 05 10;33(4):325-333. Epub 2017 Apr 10.

1 F.I. Proctor Foundation, University of California , San Francisco, San Francisco, California.

Necrobiotic xanthogranuloma (NXG) is a chronic, progressive non-Langerhans histiocytic granulomatous disease. While case reports describing periorbital involvement of NXG are frequent, only a few case reports describing ocular involvement, such as scleritis and uveitis, exist. Herein, we present a case presenting initially as bilateral anterior and posterior scleritis, as well as a chronic bilateral granulomatous panuveitis, and discuss the immunosuppressant options that should be considered for this disease with protean manifestations. Read More

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http://dx.doi.org/10.1089/jop.2016.0135DOI Listing
May 2017
6 Reads

Non-cirrhotic portal hypertension in necrobiotic xanthogranuloma associated with monoclonal gammopathy.

J Eur Acad Dermatol Venereol 2017 Sep 31;31(9):e403-e405. Epub 2017 Mar 31.

Department of Clinical Immunology, Saint-Louis Hospital, 75010, Paris, France.

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http://dx.doi.org/10.1111/jdv.14213DOI Listing
September 2017

Adult Xanthogranulomatous Disease of the Orbit: Clinical Presentations, Evaluation, and Management.

Actas Dermosifiliogr 2017 Jun 3;108(5):400-406. Epub 2017 Mar 3.

Servicio de Dermatología, Hospital General Universitario de Valencia, Valencia, España.

Adult xanthogranulomatous disease of the orbit refers to a heterogeneous group of clinical syndromes with differing degrees of systemic involvement and distinct prognoses. The different syndromes all present clinically with progressively enlarging, yellowish lesions of the orbit. Histologically, the lesions are characterized by an inflammatory infiltrate of foam cells and Touton-type multinucleated giant cells. Read More

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http://dx.doi.org/10.1016/j.ad.2016.12.005DOI Listing
June 2017
14 Reads

Image Gallery: Necrobiotic xanthogranuloma in association with chronic myelomonocytic leukaemia.

Br J Dermatol 2017 02;176(2):e16

Department of Dermatology, University of Virginia, PO Box 800718, Charlottesville, VA, 22908, U.S.A.

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http://dx.doi.org/10.1111/bjd.15285DOI Listing
February 2017
1 Read

Periocular Necrobiotic Xanthogranuloma Successfully Treated with Intravenous Immunoglobulin.

Acta Derm Venereol 2017 06;97(6):754-755

Department of Dermatology, University Hospital Jena, Erfurter Str. 35, DE-07743 Jena, Germany.

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http://dx.doi.org/10.2340/00015555-2626DOI Listing
June 2017
6 Reads

Adult-onset asthma and periocular xanthogranuloma: A rare case report.

Can J Ophthalmol 2016 Dec 25;51(6):e168-e171. Epub 2016 Aug 25.

Department of Pathology, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.

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http://dx.doi.org/10.1016/j.jcjo.2016.06.011DOI Listing
December 2016
3 Reads

Hypercalcemia in Necrobiotic Xanthogranuloma: First Reported Case and Insight Into Treatment.

J Bone Miner Res 2017 04 27;32(4):784-787. Epub 2016 Dec 27.

Main Line Endocrinology, Lankenau Medical Center, Wynnewood, PA, USA.

Necrobiotic xanthogranuloma (NXG) is a rare systemic and progressive granulomatous disease first described in 1980. Given no established first-line therapy, treatment focuses on the control of skin lesions and associated complications. Despite it being a granulomatous disease, NXG has not been associated with hypercalcemia. Read More

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http://doi.wiley.com/10.1002/jbmr.3047
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http://dx.doi.org/10.1002/jbmr.3047DOI Listing
April 2017
27 Reads

[Disseminated necrobiotic xanthogranuloma].

Hautarzt 2016 Nov;67(11):902-906

Klinik für Dermatologie und Allergologie, Krankenhaus Dresden-Friedrichstadt, Städtisches Klinikum, Akademisches Lehrkrankenhaus der TU Dresden, Friedrichstr. 41, 01067, Dresden, Deutschland.

Necrobiotic xanthogranuloma is a rare non-Langerhans-cell histiocytosis. A 62-year-old woman presented with yellowish erythematous plaques, nodules, and papules in the periorbital region and the extremities. She had a nodular tumor grown on the left upper lid that clinically resembled a keratoacanthoma. Read More

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http://link.springer.com/10.1007/s00105-016-3839-6
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http://dx.doi.org/10.1007/s00105-016-3839-6DOI Listing
November 2016
5 Reads

Necrobiotic xanthogranuloma treated with a combination of oral methylprednisolone and cyclosporin.

J Dermatol 2017 Oct 28;44(10):1190-1191. Epub 2016 Oct 28.

Department of Dermatology, School of Medicine, Pusan National University, Busan, Korea.

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http://dx.doi.org/10.1111/1346-8138.13648DOI Listing
October 2017
21 Reads

IgG4 Disease: Is It or Isn't It?

J Neuroophthalmol 2017 03;37(1):70-74

Department of Ophthalmology and Visual Sciences (STJ, MHA, AYL, HEM, PWM), Illinois Eye and Ear Infirmary, University of Illinois, Chicago, Chicago, Illinois Department of Radiology (AS), University of Michigan Health System, Ann Arbor, Michigan.

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http://dx.doi.org/10.1097/WNO.0000000000000446DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5792063PMC
March 2017
49 Reads
1.810 Impact Factor

Treatment of necrobiotic xanthogranuloma - a systematic review.

J Eur Acad Dermatol Venereol 2017 Feb 19;31(2):221-235. Epub 2016 Jul 19.

Department of Dermatology, University Hospital, Jena, Germany.

Necrobiotic xanthogranuloma (NXG) is an uncommon non-Langerhans cell histiocytosis involving skin and extracutaneous tissues. The lesions are usually asymptomatic and commonly appear in the periorbital area. Paraproteinemia is closely associated with NXG and its pathogenesis remains unclear. Read More

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http://dx.doi.org/10.1111/jdv.13786DOI Listing
February 2017
3 Reads

Clinical Features and Treatment Outcomes of Patients With Necrobiotic Xanthogranuloma Associated With Monoclonal Gammopathies.

Clin Lymphoma Myeloma Leuk 2016 08 5;16(8):447-52. Epub 2016 May 5.

Divisions of Hematology and Blood and Marrow Transplantation, Mayo Clinic, Rochester, MN. Electronic address:

Introduction: Necrobiotic xanthogranuloma (NXG) is a rare chronic granulomatous disorder of the skin associated with a monoclonal gammopathy.

Patients And Methods: The present report describes the findings from a single tertiary medical center retrospective study, including the clinical features of 35 patients with NXG and monoclonal gammopathy from 2000 to 2015 and their subsequent disease course and treatment response. The median age at diagnosis was 56 years (range, 26-88 years). Read More

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http://dx.doi.org/10.1016/j.clml.2016.04.009DOI Listing
August 2016
54 Reads

Adult-onset asthma and periocular xanthogranuloma with orbital involvement: A rare entity.

Ann Allergy Asthma Immunol 2016 May 24;116(5):466-7. Epub 2016 Mar 24.

Department of Orbit Oculoplasty, Reconstructive, and Aesthetic Services, Medical Research Foundation, Sankara Nethralaya, Chennai, India.

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http://dx.doi.org/10.1016/j.anai.2016.02.019DOI Listing
May 2016
1 Read

Xanthogranuloma in the heavily irradiated low neck in a patient with head and neck cancer.

J Otolaryngol Head Neck Surg 2016 Mar 24;45:20. Epub 2016 Mar 24.

Department of Radiation Oncology, University of California, San Francisco, 1600 Divisadero St, Suite H-1031, San Francisco, CA, 94143 - 1708, USA.

Background: Head and neck cancer is often managed with a combination of surgery, radiation therapy, and chemotherapy, and skin toxicity is not uncommon. Xanthogranuloma is a pathological finding resulting from an inflammatory reaction that has not been previously reported following head and neck radiation therapy.

Case Presentation: A patient with squamous cell carcinoma of the oropharynx, treated with definitive chemoradiation and hyperthermia, presented at eight-month follow-up with an in-field cutaneous lesion in the low neck, initially concerning for recurrent tumor. Read More

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http://dx.doi.org/10.1186/s40463-016-0134-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806421PMC
March 2016
29 Reads

Distinctive Pattern of Adipophilin Expression in Necrobiotic Xanthogranuloma.

Am J Dermatopathol 2016 Jun;38(6):468-70

*Department of Biomedicine and Prevention, Institute of Anatomic Pathology, University of Rome Tor Vergata, Rome, Italy †Unit of Dermatopathology, San Gallicano Dermatological Institute, IRCCS Rome, Rome, Italy ‡Research Unit of Dermatopathology, Department of Dermatology, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.1097/DAD.0000000000000409DOI Listing
June 2016
15 Reads

Ophthalmological considerations in necrobiotic xanthogranuloma.

Authors:
F R Ali H S Young

Clin Exp Dermatol 2016 Jul 2;41(5):563-4. Epub 2016 Mar 2.

Dermatology Centre, University of Manchester, Manchester Academic Health Science Centre, Salford Royal NHS Foundation Trust, Manchester, M6 8HD, UK.

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http://dx.doi.org/10.1111/ced.12826DOI Listing
July 2016
3 Reads

Multisystem diseases affecting the skin and eye.

Clin Dermatol 2016 Mar-Apr;34(2):214-41. Epub 2015 Nov 22.

Department of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. Electronic address:

There exist a wide variety of multisystem diseases that can affect both the eyes and skin. The skin and eyes may be the initial sites affected, leading to a new diagnosis of a systemic illness, or severe skin and eye involvement can drive treatment for patients with multisystem disease. It is important for physicians to be aware of how to recognize and diagnose these conditions, to evaluate patients for extent of disease, and to initiate appropriate therapies to combat these potentially severe diseases. Read More

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http://dx.doi.org/10.1016/j.clindermatol.2015.11.013DOI Listing
December 2016
18 Reads

A 55-Year-Old Man With Periorbital and Inguinal Masses, Pericarditis, and Pleuritis.

Arthritis Care Res (Hoboken) 2017 05 7;69(5):730-736. Epub 2017 Apr 7.

Washington University School of Medicine in St. Louis, St. Louis, Missouri.

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http://dx.doi.org/10.1002/acr.22843DOI Listing
May 2017
15 Reads

Necrobiotic xanthogranuloma associated with monoclonal gammopathy: successful treatment with lenalidomide and dexamethasone.

Ann Hematol 2016 Mar 27;95(4):671-2. Epub 2016 Jan 27.

Department of Hematology-Oncology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.

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http://dx.doi.org/10.1007/s00277-016-2604-3DOI Listing
March 2016
9 Reads

A rare case of disseminated skin and mucosal necrobiotic xanthogranuloma and xanthoma.

J Eur Acad Dermatol Venereol 2017 Jan 25;31(1):e3-e5. Epub 2016 Jan 25.

Department of Dermatology, Saint-Louis Hospital, Paris, France.

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http://dx.doi.org/10.1111/jdv.13577DOI Listing
January 2017
2 Reads

Necrobiotic Xanthogranuloma Treated With Topical Nitrogen Mustard (Mechlorethamine).

JAMA Dermatol 2016 05;152(5):589-90

Perelman School of Medicine at the University of Pennsylvania, Department of Dermatology, Philadelphia.

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http://dx.doi.org/10.1001/jamadermatol.2015.5151DOI Listing
May 2016
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Posterior Scleritis and Necrobiotic Xanthogranuloma.

Ocul Immunol Inflamm 2016 30;24(1):91-2. Epub 2015 Dec 30.

a Dermatology Centre, University of Manchester , Manchester Academic Health Science Centre, Salford Royal NHS Foundation Trust , Manchester , United Kingdom.

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http://dx.doi.org/10.3109/09273948.2015.1094571DOI Listing
August 2016
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BRAF Mutations in Erdheim-Chester Disease.

Dermatol Clin 2016 Jan;34(1):xi-xii

Unit of Medicine and Clinical Immunology, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Via Olgettina 60, 20132 Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.det.2015.10.002DOI Listing
January 2016
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