693 results match your criteria Neck Dissection Classification


Patterns of lymph node metastasis and the management of neck dissection for parotid carcinomas: a single-institute experience.

Int J Clin Oncol 2019 Feb 9. Epub 2019 Feb 9.

Department of Otorhinolaryngology-Head and Neck Surgery, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki, Osaka, 569-8686, Japan.

Background: There is no consensus about the indications and range of neck dissection in patients who have parotid carcinoma, with elective neck dissection for cN0 disease being particularly controversial.

Methods: This study retrospectively reviewed 185 patients with newly diagnosed parotid carcinoma who were treated at our department between September 1999 and August 2018.

Results: 50 of the 185 patients had lymph node metastasis, including 7. Read More

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http://dx.doi.org/10.1007/s10147-019-01411-3DOI Listing
February 2019
1 Read

Unknown primary of the head and neck: a new entry in the TNM staging system with old dilemmas for everyday practice.

Curr Opin Otolaryngol Head Neck Surg 2019 Jan 28. Epub 2019 Jan 28.

Department of Otorhinolaryngology, Maxillofacial, and Thyroid Surgery, Fondazione IRCCS National Cancer Institute of Milan.

Purpose Of Review: To summarize the most recent nuances in diagnosis, management, and prognostic stratification of carcinoma of unknown primary of the head and neck (CUPHN), in light of its recent re-assessment in the eighth edition of the TNM Classification Manual.

Recent Findings: At least in Western Countries, most CUPHN are expected to be Human Papilloma Virus (HPV)-positive with an oropharyngeal origin. Their appropriate diagnosis starts with fine needle aspiration cytology and/or core biopsy of pathologic lymph node(s) with staining for p16 by immunohistochemistry and subsequent HPV detection by PCR. Read More

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http://dx.doi.org/10.1097/MOO.0000000000000528DOI Listing
January 2019
1 Read

Number of positive lymph nodes better predicts survival for oral cavity cancer.

J Surg Oncol 2019 Jan 23. Epub 2019 Jan 23.

Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

Background: We compared the predictive ability of our proposed N classification with that of the American Joint Committee on Cancer (AJCC) nodal (N) classification for oral cavity squamous cell carcinoma (OCC).

Methods: We assessed 345 OCC patients who underwent primary tumor extirpation and neck lymph node (LN) dissection. N classification was analyzed by recursive partitioning analysis and compared with the AJCC N classification by c-index. Read More

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http://dx.doi.org/10.1002/jso.25386DOI Listing
January 2019
2 Reads

Controversies in relation to neck management in N0 early oral tongue cancer.

Jpn J Clin Oncol 2019 Jan 22. Epub 2019 Jan 22.

Department of Head and Neck Surgery, National Cancer Center Hospital East, Chiba, Japan.

The standard local treatment for early-stage tongue cancer with no clinical lymph node metastases is partial glossectomy. The frequency of occult lymph node metastasis is ~20-30%. Thus, whether prophylactic neck dissection with glossectomy or glossectomy alone should be performed has been a controversial issue since the 1980s. Read More

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http://dx.doi.org/10.1093/jjco/hyy196DOI Listing
January 2019

High metastatic node number, not extranodal extension, as a node-related prognosticator in surgically treated patients with nodal metastatic salivary gland carcinoma.

Head Neck 2019 Jan 16. Epub 2019 Jan 16.

Department of Medical Oncology, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan, Republic of China.

Background: The prognostic relevance of extranodal extension (ENE) for salivary gland carcinoma (SGC) remains unclear. The present study is undertaken to investigate the predictive significance of pathological nodal parameters in surgically treated patients with nodal metastatic SGC.

Methods: This multicenter cohort included 114 patients with pathologically proven node-positive SGC between 2000 and 2014. Read More

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http://doi.wiley.com/10.1002/hed.25603
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http://dx.doi.org/10.1002/hed.25603DOI Listing
January 2019
4 Reads

Classification of Hypoparathyroid Disorders.

Front Horm Res 2019 19;51:127-138. Epub 2018 Nov 19.

The term hypoparathyroidism encompasses a huge group of disorders all characterized by an abnormal mineral homeostasis determined by inadequate secretion of parathyroid hormone. Postsurgical hypoparathyroidism is a complication of neck surgery (thyroidectomy, parathyroidectomy, lymph node, and cancer neck dissection), closely related to the extent of the surgical procedure and the experience of the surgeon. If lasting more than 6 months it is defined as chronic hypoparathyroidism, requiring life-long replacement therapy with active vitamin D metabolites. Read More

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http://dx.doi.org/10.1159/000491043DOI Listing
November 2018
2 Reads

[Neck dissection-Surgical treatment of cervical lymphatic drainage pathways].

HNO 2019 Jan;67(1):61-76

Klinik für Hals‑, Nasen‑, Ohrenheilkunde und Kopf-Hals-Chirurgie, Universitätsklinikum Ulm, Frauensteige 12, 89075, Ulm, Deutschland.

Neck dissection (ND) is an essential component of treatment in head and neck squamous cell carcinoma (HNSCC). The extent of ND depends on primary tumor location and T and N stage. Trials have demonstrated improved survival for cN+ status with therapeutic ND as well as for cN0 status with selective ND if the primary has a high incidence of occult metastasis. Read More

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http://dx.doi.org/10.1007/s00106-018-0601-7DOI Listing
January 2019

A comparison of the 7th and 8th editions of the AJCC staging system in terms of predicting recurrence and survival in patients with papillary thyroid carcinoma.

Oral Oncol 2018 Dec 9;87:158-164. Epub 2018 Nov 9.

Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

Objectives: The recently published 8th edition of the American Joint Committee on Cancer (AJCC) tumour-node-metastasis (TNM) staging system was significantly updated following the thyroid cancer-related guidelines to provide better predictability of survival but not focus on recurrence. Therefore, we compared the predictive values of the 7th and 8th editions of the AJCC staging systems for recurrence-free survival (RFS) and overall survival (OS) after thyroidectomy for papillary thyroid carcinoma (PTC).

Methods: This retrospective study included 2930 patients who underwent thyroidectomy and neck dissection for previously untreated PTC between 2006 and 2014. Read More

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http://dx.doi.org/10.1016/j.oraloncology.2018.11.003DOI Listing
December 2018

Data Set for the Reporting of Nodal Excisions and Neck Dissection Specimens for Head and Neck Tumors: Explanations and Recommendations of the Guidelines From the International Collaboration on Cancer Reporting (ICCR).

Arch Pathol Lab Med 2018 Nov 30. Epub 2018 Nov 30.

From the Department of Pathology, Dalhousie University and Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada (Dr Bullock); the Department of Radiation Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia (Dr Beitler); the Pathology and Laboratory Medicine Institute, Cleveland Clinic, Weston, Florida (Dr Carlson); the Instituto de Anatomia Patológica, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal (Dr Fonseca); the Department of Pathology, University of Arkansas for Medical Sciences, Little Rock (Dr Hunt); the Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York (Dr Katabi); the Department of Cellular Pathology, Newcastle University, Newcastle upon Tyne, United Kingdom (Dr Sloan); the Department of Surgery, Division of Otolaryngology-Head and Neck Surgery, Dalhousie University, Halifax, Nova Scotia, Canada (Dr Taylor); the Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston (Dr Williams); and the Department of Pathology, Southern California Permanente Medical Group, Woodland Hills Medical Center, Woodland Hills, California (Dr Thompson).

Standardized, synoptic pathologic reporting for tumors greatly improves communication among clinicians, patients, and researchers, supporting prognostication and comparison about patient outcomes across institutions and countries. The International Collaboration on Cancer Reporting is a nonprofit organization whose mission is to develop evidence-based, universally available surgical pathology reporting data sets. Within the head and neck region, lymph node excisions and neck dissections are frequently performed as part of the management of head and neck cancers arising from the mucosal sites (sinonasal tract, nasopharynx, oropharynx, hypopharynx, oral cavity, and larynx), along with bone tumors, skin cancers, melanomas, and other tumor categories. Read More

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http://dx.doi.org/10.5858/arpa.2018-0421-SADOI Listing
November 2018
1 Read

Ansa cervicalis - A new classification approach.

Ann Anat 2019 Mar 17;222:55-60. Epub 2018 Nov 17.

Department of Human Anatomy, Federal State Autonomous Educational Institution of Higher Education I. M. Sechenov First Moscow State Medical University of the Ministry of Healthcare of the Russian Federation (Sechenovskiy University), Moscow, Russia. Electronic address:

Normally, the inferior root of Ansa cervicalis passes around the internal jugular vein and runs in an anterior direction to meet the superior root ventral to the common carotid artery. However, anatomical variants of the Ansa cervicalis are as yet not well investigated and understood. To close this gap the present study was undertaken. Read More

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http://dx.doi.org/10.1016/j.aanat.2018.10.010DOI Listing
March 2019
20 Reads

Management of the Neck in Oral Squamous Cell Carcinoma: Background, Classification, and Current Philosophy.

Oral Maxillofac Surg Clin North Am 2019 Feb;31(1):69-84

Department of Oral and Maxillofacial Surgery, University of Michigan, Ann Arbor, MI, USA.

Nodal metastasis is the single most prognostic determinant in patients with oral squamous cell carcinoma (OSCC). Since its inception more than a century ago, the management of the neck has led to decreased surgical morbidity, with continued preservation of oncologic safety for OSCC. Nodal metastasis is the single most prognostic determinant in patients with OSCC. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10423699183008
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http://dx.doi.org/10.1016/j.coms.2018.09.004DOI Listing
February 2019
15 Reads

[Hybrid prosthesis for vascular reconstruction of the internal carotid artery near the skull base after radical excision of a very rare malignant glomus caroticum paraganglioma].

HNO 2018 Oct 30. Epub 2018 Oct 30.

Fachbereich Gefäßchirurgie, Klinik für Allgemein‑, Viszeral‑, Gefäß- und Transplantationschirurgie, Universitätsklinikum Magdeburg A.ö.R., Leipziger Str. 44, 39120, Magdeburg, Deutschland.

Background: Neck tumors are challenging regarding the diagnostic and therapeutic management particularly in cases of malignant growth near relevant vessels to achieve R0 resection status and the best prognosis.

Aim: The aim of this case report on a patient with a rare malignant tumor of the glomus caroticum (paraganglioma) is to present the successful outcome of a demanding interdisciplinary surgical approach (otorhinolaryngology and vascular surgery). Surgical re-intervention was necessary due to malignant tumor growth (detected in the histopathological investigation of the first specimen) including vascular resection using a hybrid graft for vascular reconstruction of the internal carotid artery near the skull base. Read More

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http://link.springer.com/10.1007/s00106-018-0588-0
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http://dx.doi.org/10.1007/s00106-018-0588-0DOI Listing
October 2018
7 Reads

Predicting 90-Day Mortality in Locoregionally Advanced Head and Neck Squamous Cell Carcinoma after Curative Surgery.

Cancers (Basel) 2018 Oct 22;10(10). Epub 2018 Oct 22.

Department of Radiation Oncology, Wanfang Hospital, Taipei Medical University, Taipei 116, Taiwan.

To propose a risk classification scheme for locoregionally advanced (Stages III and IV) head and neck squamous cell carcinoma (LA-HNSCC) by using the Wu comorbidity score (WCS) to quantify the risk of curative surgeries, including tumor resection and radical neck dissection. This study included 55,080 patients with LA-HNSCC receiving curative surgery between 2006 and 2015 who were identified from the Taiwan Cancer Registry database; the patients were classified into two groups, mortality ( = 1287, mortality rate = 2.34%) and survival ( = 53,793, survival rate = 97. Read More

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http://www.mdpi.com/2072-6694/10/10/392
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http://dx.doi.org/10.3390/cancers10100392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210656PMC
October 2018
9 Reads

[The interpretation of the Chinese expert consensus on mediastinal lymph node dissection in esophagectomy for esophageal cancer (2017 edition)].

Zhonghua Wei Chang Wai Ke Za Zhi 2018 Sep;21(9):976-982

Department of Thoracic Surgery, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China Email:

At present, there is still no general consensus on the thoracic lymph node classification and dissection standard of esophageal cancer, and its indications, surgical approaches, harvested number and scopes are still the debated focuses in the academic circle. Therefore, the Society of Esophageal Tumor, Chinese Anti-Cancer Association organized experts in the field to write the Chinese expert consensus on mediastinal lymph node dissection in esophagectomy for esophageal cancer (2017 edition) based on clinical experience and current available evidence. This article focuses on the surgical approach and recurrent laryngeal nerve lymph node dissection in esophageal cancer. Read More

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September 2018
1 Read

Nomograms for prediction of postoperative complications in open partial laryngeal surgery.

J Surg Oncol 2018 Nov 27;118(6):1050-1057. Epub 2018 Sep 27.

Department of Surgery and Translational Medicine, Division of Otolaryngology, University of Florence, Firenze, Italy.

Background And Objectives: Postoperative morbidity after open partial laryngeal surgery (OPLS) may be serious, leading to a prolonged length of hospital stay and increasing costs. We sought to define the predictive factors of complications and to develop nomograms for patients eligible for OPLS based on clinical and surgical data.

Methods: We critically reviewed 535 patients with laryngeal carcinoma who underwent OPLS at our Institution from 1982 to 2007. Read More

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http://dx.doi.org/10.1002/jso.25232DOI Listing
November 2018
10 Reads

CO Transoral Microsurgery for Supraglottic Squamous Cell Carcinoma.

Front Oncol 2018 4;8:321. Epub 2018 Sep 4.

Unit of Otorhinolaryngology, Department of Surgery, Azienda Ospedaliero-Universitaria di Cagliari, University of Cagliari, Cagliari, Italy.

The present study analyzed the results of the endoscopic approach to T1, T2 and selected T3 supraglottic carcinoma with the aim of reviewing functional and oncologic outcomes after different types of endoscopic supraglottic laryngectomies. This is a retrospective clinical study of 42 consecutive patients (mean age of 61.8 years, 33 males, 9 females) treated by the senior author for supraglottic squamous cell carcinoma with a transoral CO laser approach and reviewed from November 2010 to September 2017. Read More

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http://dx.doi.org/10.3389/fonc.2018.00321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131582PMC
September 2018
7 Reads

Obesity and High Risk Pathological Features of Papillary Thyroid Carcinoma: A Retrospective Analysis of a University Hospital in Pakistan.

Gulf J Oncolog 2018 May;1(27):6-10

Department of Otorhinolaryngology-Head and Neck Surgery, Liaquat National Hospital and Medical College, Karachi, Pakistan.

Background: Incidence of papillary thyroid carcinoma (PTC) and the frequency of obesity is increasing globally. In literature, relationship between excessive body weight and bad prognostic features of PTC is still debatable. In this study, we aimed to explore the association of obesity with high risk pathological features of PTC in a population treated by total thyroidectomy +/- neck dissection. Read More

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May 2018
2 Reads

Noninvasive follicular thyroid neoplasm with papillary-like nuclear features reclassification and its impact on thyroid malignancy rate and treatment.

J Surg Res 2018 Oct 16;230:47-52. Epub 2018 May 16.

Division of Endocrine Surgery, DeWitt Daughtry Family, Department of Surgery, University of Miami, Leonard M. Miller School of Medicine, Miami, Florida.

Background: The reclassification of noninvasive encapsulated follicular variant papillary thyroid carcinoma (FVPTC) to noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) may have significant implications by changing overall malignancy rates and minimizing the extent of surgical treatment.

Methods: A retrospective review of 847 patients who underwent thyroidectomy at a single institution from January 2010 to April 2016 was performed. The subgroup with FVPTC (n = 181) was re-reviewed by endocrine pathologists for reclassification to NIFTP. Read More

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http://dx.doi.org/10.1016/j.jss.2018.04.013DOI Listing
October 2018
3 Reads

Robot-assisted mediastinoscopic esophagectomy for esophageal cancer: the first clinical series.

Esophagus 2019 01 3;16(1):85-92. Epub 2018 Aug 3.

Department of Surgery, Fujita Health University, 1-98 Dengakugakubo, Kutsukake, Toyoake, Aichi, 470-1192, Japan.

Background: Radical esophagectomy for esophageal cancer is associated with high morbidity, especially with pulmonary complications. Mediastinoscopic esophagectomy via a small left neck incision combined with the esophageal hiatus, without using transthoracic approach, has been reported to reduce pulmonary complication; however, from technical point of view, this approach using non-articulating, straight, long forceps is extremely challenging, especially in the middle mediastinal area. Its technical difficulties may be attenuated using da Vinci Surgical System. Read More

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http://dx.doi.org/10.1007/s10388-018-0634-8DOI Listing
January 2019
7 Reads

Lingual lymph nodes in patients with squamous cell carcinoma of the tongue and the floor of the mouth.

Head Neck 2018 Nov 26;40(11):2383-2388. Epub 2018 Jul 26.

Department of Stomatology, Second Affiliated Hospital of Nanchang University, Nanchang, 330006, China.

Background: The treatment failure for oral squamous cell carcinoma (SCC) frequently takes the form of local and regional recurrences. We investigated the role of lingual lymph nodes (LLNs) in the recurrence of SCC of the tongue and the floor of the mouth.

Methods: A total of 111 patients with SCC of the tongue and the floor of the mouth who received treatment between 2012 and 2017 were included in this study. Read More

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http://dx.doi.org/10.1002/hed.25340DOI Listing
November 2018
2 Reads

Impact of anatomic origin of primary squamous cell carcinomas of the nasal cavity and ethmoidal sinus on clinical outcome.

Eur Arch Otorhinolaryngol 2018 Sep 19;275(9):2363-2371. Epub 2018 Jul 19.

Department of Otorhinolaryngology, Head and Neck Surgery, Medical University Vienna, Vienna, Austria.

Purpose: Since squamous cell carcinomas (SCCs) of the nasoethmoidal complex are rare and aggressive malignancies, the purpose of this study was to evaluate whether anatomic subsites of SCCs of the nasal cavity and ethmoid sinuses affect clinical outcome.

Methods: We retrospectively analyzed data from 47 patients with primary SCCs of the nasal cavity and ethmoid sinuses who were treated at the Department of Otorhinolaryngology, Head and Neck Surgery, Medical University of Vienna, between 1993 and 2018. The impact of anatomic subsites of nasoethmoidal SCCs was evaluated with respect to tumor and nodal classification, disease-free survival (DFS) and disease-specific survival (DSS). Read More

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http://dx.doi.org/10.1007/s00405-018-5068-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096568PMC
September 2018
7 Reads

Laparoscopic Colposuspension for Recurrent Stress Incontinence after Tension-free Vaginal Tape.

J Minim Invasive Gynecol 2018 Jul 11. Epub 2018 Jul 11.

Department of Urogynaecology, Croydon University Hospital NHS Trust, Croydon, UK (Dr. Thakar).

Study Objective: To demonstrate laparoscopic colposuspension for recurrent stress incontinence after failed tension-free vaginal tape (TVT).

Design: A technical video showing laparoscopic colposuspension for previously surgically treated stress incontinence (Canadian Task Force classification III).

Setting: A university hospital. Read More

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http://dx.doi.org/10.1016/j.jmig.2018.06.017DOI Listing
July 2018
19 Reads

Predictors of internal mammary lymph nodes (IMLN) metastasis and disease-free survival comparison between IMLN-positive and IMLN-negative breast cancer patients: Results from Western China Clinical Cooperation Group (WCCCG) database (CONSORT).

Medicine (Baltimore) 2018 Jul;97(28):e11296

Department of the Endocrine and Breast Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing.

Limited studies performed a comprehensive assessment of risk factors for internal mammary lymph nodes (IMLN) metastasis, and disease-free survival (DFS) difference between IMLN-positive and IMLN-negative breast cancer (BC) patients undergoing IMLN dissection and systemic therapies was not clear.A retrospective study included 1977 BC patients from Western China Clinical Cooperation Group between January 2005 and December 2012. The impact of clinicopathological factors on the occurrence of IMLN metastasis was assessed in univariate and multivariate logistic regression analyses, and a nomogram (model) was constructed to predict the IMLN status. Read More

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http://dx.doi.org/10.1097/MD.0000000000011296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076024PMC
July 2018
26 Reads

Novel Surgical and Radiologic Classification of the Subtympanic Sinus: Implications for Endoscopic Ear Surgery.

Otolaryngol Head Neck Surg 2018 Jul 1:194599818787180. Epub 2018 Jul 1.

4 Department of Otorhinolaryngology-Head and Neck Surgery, University Hospital Verona, Verona, Italy.

Objective The aim of this study is to describe the endoscopic anatomy of the subtympanic sinus (STS), establish a classification according to its extension regarding the level of the facial nerve (FN), and assess the feasibility of the transcanal endoscopic approach to the STS. Study Design Experimental anatomic research. Setting Temporal bone laboratory. Read More

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http://dx.doi.org/10.1177/0194599818787180DOI Listing
July 2018
9 Reads

Radiologic-Pathologic Correlation of Extranodal Extension in Patients With Squamous Cell Carcinoma of the Oral Cavity: Implications for Future Editions of the TNM Classification.

Int J Radiat Oncol Biol Phys 2018 Nov 17;102(4):698-708. Epub 2018 May 17.

Department of Radiation Oncology, Princess Margaret Cancer Centre-University Health Network, University of Toronto, Toronto, Ontario, Canada. Electronic address:

Purpose: To evaluate the accuracy and prognostication of the presence of radiologic extranodal extension (rENE) versus pathologic extranodal extension (pENE) in patients with oral cavity squamous cell carcinoma (OSCC).

Methods And Materials: A retrospective review was conducted for all newly diagnosed OSCC patients who underwent neck dissection in our institution from 2010 to 2015 with available records of preoperative computed tomography or magnetic resonance imaging. Two head and neck neuroradiologists reviewed the presence of rENE (defined as ill-defined lymph node borders) on imaging independently, being blinded regarding the pathology report. Read More

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http://dx.doi.org/10.1016/j.ijrobp.2018.05.020DOI Listing
November 2018
7 Reads
4.260 Impact Factor

Hidden Scar Dissection of Benign Parotid Gland Tumors via a V-Shaped Minimal Facelift Incision.

J Craniofac Surg 2018 Nov;29(8):2299-2303

Department of Oral and Maxillofacial-Head and Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine.

Objectives: The purpose of this article was to propose a V-shaped minimal facelift incision (FLI) and analyze its efficacy for improving the esthetic outcomes of parotid gland tumors.

Methods: A prospective, nonrandomized study was performed. Forty-six patients with category I benign parotid tumors as to Quer classification (3 cm or less and located superficially and/or peripherally in the gland) were enrolled. Read More

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http://dx.doi.org/10.1097/SCS.0000000000004670DOI Listing
November 2018
3 Reads

The protympanum, protiniculum and subtensor recess: an endoscopic morphological anatomy study.

J Laryngol Otol 2018 Jun 11;132(6):489-492. Epub 2018 Jun 11.

Kolling Deafness Research Centre,Royal North Shore Hospital and Macquarie University,Sydney,Australia.

Objectives: An anatomical study was performed to describe the endoscopic anatomy and variations of the protympanum, including classification of the protiniculum and subtensor recess.

Methods: A retrospective review was conducted of video recordings of cadaveric dissections and surgical procedures, which included visualisation of the protympanum, across 4 tertiary university referral centres over a 16-month period. A total of 97 ears were used in the analysis. Read More

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http://dx.doi.org/10.1017/S0022215118000464DOI Listing

Malignant Shamblin III Carotid Body Tumors Resected with Use of the Retrocarotid Dissection Technique in 2 Patients.

Tex Heart Inst J 2018 04 7;45(2):92-95. Epub 2018 Apr 7.

Carotid body tumors are rare neoplasms with malignant potential in 6% to 12.5% of cases, and surgical resection is the only cure. We present the cases of 2 female patients who had expanding, painless, right-sided neck masses; computed tomographic angiograms revealed Shamblin III tumors at the carotid bifurcation. Read More

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http://dx.doi.org/10.14503/THIJ-16-6142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940292PMC
April 2018
11 Reads
0.630 Impact Factor

[The effect of regional neck dissection on positive cervical lymph node of cN0 laryngeal carcinoma].

Authors:
X Y Li J R Li H G Guo

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2017 Dec;31(23):1793-1796

Department of Otolaryngology Head and Neck Surgery, Navy General Hospital, Beijing,100048, China.

To evaluate the efficacy and safety of regional neck dissection in the treatment of cN0 laryngeal carcinoma with positive cervical lymph node. A retrospective analysis of 120 cases with cN0 laryngeal squamous cell carcinoma who received the first time for primary tumor resection and regional neck dissection (Ⅱ-Ⅳ) in our hospital during the period of 2000.01-2016. Read More

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http://dx.doi.org/10.13201/j.issn.1001-1781.2017.23.003DOI Listing
December 2017
1 Read

Quantitative Proteomics Analysis of Sporadic Medullary Thyroid Cancer Reveals FN1 as a Potential Novel Candidate Prognostic Biomarker.

Oncologist 2018 Dec 8;23(12):1415-1425. Epub 2018 May 8.

Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, National Key Laboratory of Medical Molecular Biology & Department of Immunology, Beijing, People's Republic of China

Background: Sporadic medullary thyroid cancer (MTC) is a rare neuroendocrine tumor. Currently, although the diagnosis of sporadic MTC is relatively simple, the need to discover novel candidate prognostic biomarkers for sporadic MTC and investigate the underlying mechanism involved in this rare disease is urgent.

Materials And Methods: We employed tandem mass tag-based liquid chromatography-mass spectrometry to identify and analyze differentially expressed proteins (DEPs) in sporadic MTC. Read More

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http://dx.doi.org/10.1634/theoncologist.2017-0399DOI Listing
December 2018
5 Reads

[Advances in the management of cervical lymphadenopathies of unknown primary with intensity modulated radiotherapy: Doses and target volumes].

Cancer Radiother 2018 Sep 3;22(5):438-446. Epub 2018 May 3.

Département de radiothérapie/Archade, centre François-Baclesse, 3, avenue General-Harris, 14000 Caen, France; Université Unicaen, 14000 Caen, France. Electronic address:

The definition of nodal and/or mucosal target volumes for radiation therapy for lymphadenopathies of unknown primary is controversial. Target volumes may include all nodal areas bilaterraly and be pan-mucosal or unilateral, selective, including the sole oropharyngeal mucosa. This review presents current recommendations in light of changes in the TNM classification, Human papillomavirus status and therapeutic advances. Read More

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http://dx.doi.org/10.1016/j.canrad.2017.10.008DOI Listing
September 2018

The importance of lymph node ratio for patients with mandibular infiltration of oral squamous cell carcinoma.

J Craniomaxillofac Surg 2018 Jun 5;46(6):1007-1012. Epub 2018 Apr 5.

Department for Oral and Craniomaxillofacial Plastic Surgery, University of Cologne, Cologne, Germany.

Purpose: Lymph node ratio (LNR) essentially improves assessment of prognosis and therapeutic decision making for patients with oral squamous cell carcinoma, as it considers both the number of positive lymph nodes and the number of dissected lymph nodes. Mandibular infiltration by oral squamous cell carcinoma is a vital clinicopathological feature, significantly worsens prognosis. However, to the best of our knowledge, data on the influence of LNR on prognosis for patients with OSCC and mandibular infiltration are not available. Read More

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http://dx.doi.org/10.1016/j.jcms.2018.03.021DOI Listing
June 2018
5 Reads

Does volumetric measurement of cervical lymph nodes serve as an imaging biomarker for locoregional recurrence of oral squamous cell carcinoma?

J Craniomaxillofac Surg 2018 Jun 10;46(6):1013-1018. Epub 2018 Apr 10.

Department for Oral and Craniomaxillofacial Plastic Surgery, University Hospital of Cologne, Cologne, Germany.

Introduction: Recent studies highlighted the prognostic superiority of lymph node volume towards the conventional N Classification. However, data on the importance of neck lymph node volume, obtained by semiautomatic segmentation of CT images, do not exist for locoregional recurrence in patients with oral squamous cell carcinoma (OSCC).

Methods: Retrospective chart review of 100 patients, who were diagnosed and treated between 2006-2014. Read More

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http://dx.doi.org/10.1016/j.jcms.2018.04.001DOI Listing
June 2018
6 Reads

Nodal response after 46 Gy of intensity-modulated radiotherapy is associated with human papillomavirus-related oropharyngeal carcinoma.

Laryngoscope 2018 10 9;128(10):2333-2340. Epub 2018 Mar 9.

Department of Otorhinolaryngology and Head and Neck Surgery, Rotterdam, the Netherlands.

Objectives/hypothesis: This study aimed to analyze the effect of human papillomavirus (HPV)-associated T1-2 node-positive oropharyngeal squamous cell carcinoma (OPSCC) on nodal response, recurrent disease, and survival in patients treated according to the Rotterdam protocol.

Study Design: Retrospective cohort study.

Methods: In total, 77 patients with T1-2 OPSCC with nodal disease, treated between 2000 and 2012, were included in this study. Read More

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http://dx.doi.org/10.1002/lary.27155DOI Listing
October 2018
4 Reads

Transoral radical tonsillectomy and retropharyngeal lymph node dissection with a flexible next generation robotic surgical system.

Head Neck 2018 Jun 23;40(6):1296-1298. Epub 2018 Feb 23.

Department of Otorhinolaryngology, Head and Neck Surgery, The Chinese University of Hong Kong, Shatin, Hong Kong SAR.

Background: The purpose of this study was to describe the use of a novel flexible, single-arm robot in performing a transoral radical tonsillectomy and retropharyngeal lymph node dissection.

Methods: A 63-year-old man with a T1N2bM0 (American Joint Committee on Cancer seventh edition classification) squamous cell carcinoma (SCC) of the left tonsil underwent a transoral robotic radical tonsillectomy and retropharyngeal lymph node dissection, followed by a left selective neck dissection of levels I to IV.

Results: The tonsillar tumor was removed completely with a negative margin that was followed by a dissection and removal of a retropharyngeal lymph node, completed with primary closure of the site. Read More

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http://dx.doi.org/10.1002/hed.25118DOI Listing
June 2018
2 Reads
1 Citation
2.641 Impact Factor

A Novel Classification and Staged Approach for Dissection Along the Celiac and Hepatic Artery During Pancreaticoduodenectomy.

World J Surg 2018 09;42(9):2963-2967

Department of Gastroenterological Surgery, Cancer Institute Hospital, Japanese Foundation for Cancer Research, 3-8-31 Ariake, Koto-ku, Tokyo, 135-8550, Japan.

Background: In recent decades, there have been enthusiastic discussions of, and active proposals for, new approaches to dissection around the superior mesenteric artery during pancreaticoduodenectomy (PD). In contrast, dissection along the celiac axis (CA) and hepatic artery (HA) and in the hepatoduodenal ligament has rarely been systematically discussed. In this report, we propose and describe a three-level classification of dissection along the CA-HA system which is applicable to a variety of diseases for which PD is indicated. Read More

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http://dx.doi.org/10.1007/s00268-018-4550-9DOI Listing
September 2018
4 Reads

A rare case report of a typical variant ossifying fibromyxoid tumor (OFMT), located in the retroauricular perimastoid region.

Int J Surg Case Rep 2018 14;44:16-19. Epub 2018 Feb 14.

Department of Otolaryngology - Head & Neck Surgery, "San Camillo-Forlanini" Hospital, Rome, Italy.

Introduction: Ossifying fibromixoid tumor of soft parts (OFMT) is a rare soft tissue and bone tumor. In its classic form, is considered benign, nevertheless aggressive clinical behaviour tumors with a different cytoarchitectural features of a malignant variant, have been described.The classification contains "typical", "atypical" and "malignant" variants. Read More

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http://dx.doi.org/10.1016/j.ijscr.2018.02.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832672PMC
February 2018
2 Reads

Postoperative chemoradiotherapy in patients with head and neck cancer aged 70 or older with positive margins or extranodal extension and the influence of nodal classification.

Head Neck 2018 Jun 8;40(6):1228-1236. Epub 2018 Feb 8.

Department of Radiation Oncology, Cedars-Sinai Medical Center, Los Angeles, California.

Background: Postoperative concomitant chemoradiotherapy (CRT) improves outcomes for younger adults with head and neck squamous cell carcinoma (HNSCC) and positive margins or extranodal extension (ENE), but its benefit for older adults is not well established.

Methods: Patients from the National Cancer Data Base (NCDB) with HNSCC undergoing curative-intent resection, neck dissection, and postoperative radiation with positive margins or ENE were identified.

Results: This analysis included 1199 patients aged ≥ 70 years with median follow-up of 42. Read More

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http://dx.doi.org/10.1002/hed.25100DOI Listing
June 2018
2 Reads

Minimally Invasive Lateral Endoscopic Multiport Approach to the Infratemporal Fossa: A Cadaveric Study.

World Neurosurg 2018 Apr 31;112:e489-e496. Epub 2018 Jan 31.

Department of Otorhinolaryngology, Head & Neck Surgery, Inselspital, University Hospital and University of Bern, Bern, Switzerland.

Background: Expanded endoscopic endonasal approaches to the infratemporal fossa (ITF) are increasingly performed owing to improved visualization and less morbidity compared with classic open approaches. Only a few studies in the literature investigated lateral endoscopic access to the ITF. The aim of this study was to examine the ITF with the minimally invasive endoscopically assisted Gillies approach with a trial of its expansion through a double port technique. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183010
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http://dx.doi.org/10.1016/j.wneu.2018.01.065DOI Listing
April 2018
32 Reads

Independent predictors and lymph node metastasis characteristics of multifocal papillary thyroid cancer.

Medicine (Baltimore) 2018 Feb;97(5):e9619

Thyroid and Parathyroid Surgery Center, West China Hospital.

The multifocal papillary thyroid cancer (PTC), with more aggressive and poorer prognosis, is not rare in papillary histotype. Few studies evaluated risk factors and lymph node metastasis in multifocal PTC. The aim of this present study focusing on risk factors and lymph node metastasis characteristics in multifocal PTC was excepted to assist clinical decisions regarding surgery. Read More

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http://dx.doi.org/10.1097/MD.0000000000009619DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805413PMC
February 2018
10 Reads

Oncologic outcomes of extended neck dissections in human papillomavirus-related oropharyngeal squamous cell carcinoma.

Head Neck 2018 May 29;40(5):955-962. Epub 2018 Jan 29.

Department of Otolaryngology - Head and Neck Surgery, Washington University, Saint Louis, Missouri.

Background: Oncologic outcomes of human papillomavirus (HPV)-related oropharyngeal squamous cell carcinoma (SCC) requiring resection of major muscular or neurovascular tissue during neck dissection for invasive nodal disease remain uncertain.

Methods: Patients with HPV-related oropharyngeal SCC requiring resection of major muscular or neurovascular tissue during their neck dissections were retrospectively identified.

Results: Seventy-two patients were included. Read More

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http://dx.doi.org/10.1002/hed.25060DOI Listing
May 2018
10 Reads

Postoperative staging of the neck dissection using extracapsular spread and lymph node ratio as prognostic factors in HPV-negative head and neck squamous cell carcinoma patients.

Oral Oncol 2018 Feb 18;77:37-42. Epub 2017 Dec 18.

Otorhinolaryngology Department, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Madrid, Spain. Electronic address:

Objectives: The presence of nodes with extracapsular spread (ECS) and the lymph node ratio (LNR) have prognostic competence in the pathologic evaluation of patients with a head and neck squamous cell carcinoma (HNSCC) treated with a neck dissection. The purpose of this study is to assess the effect of ECS & LNR on prognosis of HPV negative HNSCC patients treated with neck dissection and to compare to 8th edition TNM/AJCC classification.

Materials And Methods: We carried out a retrospective study of 1383 patients with HNSCC treated with a neck dissection between 1985 and 2013. Read More

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http://dx.doi.org/10.1016/j.oraloncology.2017.12.010DOI Listing
February 2018
9 Reads

Does the surgical approach for treating mandibular condylar fractures affect the rate of seventh cranial nerve injuries? A systematic review and meta-analysis based on a new classification for surgical approaches.

J Craniomaxillofac Surg 2018 Mar 14;46(3):398-412. Epub 2017 Nov 14.

Department of Oral and Maxillofacial Surgery, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.

Purpose: The purpose of this study was to determine the rate of facial nerve injury (FNI) when performing (ORIF) of mandibular condylar fractures by different surgical approaches.

Materials And Methods: A systematic review and meta-analysis were performed that included several databases with specific keywords, a reference search, and a manual search for suitable articles. The inclusion criteria were all clinical trials, with the aim of assessing the rate of facial nerve injuries when (ORIF) of mandibular condylar fractures was performed using different surgical approaches. Read More

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http://dx.doi.org/10.1016/j.jcms.2017.10.024DOI Listing
March 2018
6 Reads
2.600 Impact Factor

Quality of life and problems associated with obturators of patients with maxillectomies.

Head Face Med 2018 Jan 5;14(1). Epub 2018 Jan 5.

Department of Oral Rehabilitation, Faculty of Dentistry, University of Khartoum, Khartoum, Sudan.

Background: Maxillary defects predispose patients to different undesirable effects. The aim of this study was to assess the quality of life (QoL) of patients with maxillary defects (acquired/congenital) wearing obturators.

Methods: The study comprised 30 patients aged between 16 and 78 years. Read More

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http://dx.doi.org/10.1186/s13005-017-0160-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795281PMC
January 2018
2 Reads
0.870 Impact Factor

[Advances in the management of cervical lymphadenopathies of unknown primary: advances in diagnostic imaging and surgical modalities and new international staging system].

Bull Cancer 2018 Feb 21;105(2):181-192. Epub 2017 Dec 21.

ARCHADE centre François-Baclesse, radiothérapie, 3, avenue du Général-Harris, 14000 Caen, France. Electronic address:

Introduction: Cervical lymphadenopathies of unknown primary represent 3 % of head and neck cancers. Their diagnostic work up has largely changed in recent years. This review provides an update on diagnostic developments and their potential therapeutic impact. Read More

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http://dx.doi.org/10.1016/j.bulcan.2017.11.009DOI Listing
February 2018
12 Reads

Translation and adaptation to Brazilian Portuguese of the Lymphedema Rating Scale in Head and Neck Cancer.

Einstein (Sao Paulo) 2017 Oct-Dec;15(4):457-464. Epub 2017 Dec 18.

Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.

Objective: Translate to brazilian portuguese, culturally adapt and test the rating and classification scales of cervicofacial lymphedema of the MD Anderson Cancer Center Head and Neck Lymphedema Protocol (MDACC HNL) in patients undergoing treatment for head and neck cancer.

Methods: The process followed international guidelines and translation stages by two head and neck surgeons, and back translation independently by two native Americans. The test of final version was based on the evaluation of 18 patients by one speech pathologist and one physical therapist who applied the scales in Portuguese. Read More

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http://dx.doi.org/10.1590/S1679-45082017AO3995DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875160PMC
March 2018
7 Reads

Endoscopic Anatomy of the Tensor Fold and Anterior Attic.

Otolaryngol Head Neck Surg 2018 02 19;158(2):358-363. Epub 2017 Dec 19.

1 Department of Otolaryngology-Head and Neck Surgery, University of Minnesota, Minneapolis, Minnesota, USA.

Objectives The objectives of the study were to (1) study the anatomical variations of the tensor fold and its anatomic relation with transverse crest, supratubal recess, and anterior epitympanic space and (2) explore the most appropriate endoscopic surgical approach to each type of the tensor fold variants. Study Design Cadaver dissection study. Setting Temporal bone dissection laboratory. Read More

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http://journals.sagepub.com/doi/10.1177/0194599817739295
Publisher Site
http://dx.doi.org/10.1177/0194599817739295DOI Listing
February 2018
8 Reads

Prognostic value of the lymph node ratio in oropharyngeal carcinoma stratified for HPV-status.

Eur Arch Otorhinolaryngol 2018 Feb 4;275(2):515-524. Epub 2017 Dec 4.

Department of Otorhinolaryngology, Head and Neck Surgery, Ludwig-Maximilians-Universität, Marchioninistr. 15, 81377, Munich, Germany.

Objective: Lymph node ratio (LNR) was shown to be a prognostic factor in laryngeal and oral cavity primaries. The purpose of this study was to investigate the impact of the lymph node ratio in oropharyngeal squamous cell carcinoma (OPSCC) with a high incidence of HPV-related disease. Therefore, the role of LNR was evaluated as an additional predictive parameter to the 8th edition of AJCC TNM staging system. Read More

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http://dx.doi.org/10.1007/s00405-017-4833-zDOI Listing
February 2018
7 Reads

Survival Outcome of Intermediate-Grade Salivary Gland Carcinoma.

Oncology 2018 18;94(2):125-132. Epub 2017 Nov 18.

Department of Otolaryngology, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Republic of Korea.

Objective: Histological grade is the most important factor for defining treatment strategies and predicting prognosis for salivary gland carcinoma (SGC). We examined factors affecting long-term recurrence and survival among intermediate-grade SGC (IGSGC) patients to define optimal treatment modalities and outcomes.

Methods: We reviewed the clinical and pathological data on 108 IGSGC patients who underwent definitive surgery with or without postoperative radiotherapy. Read More

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http://dx.doi.org/10.1159/000484411DOI Listing
March 2018
12 Reads

Clinicodemographic profile and treatment outcome in patients of ocular surface squamous neoplasia.

Indian J Ophthalmol 2017 Oct;65(10):936-941

Dr. R P Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Purpose: The aim is to study the clinicodemographic profile and treatment outcome of ocular surface squamous neoplasia (OSSN).

Methods: This was a retrospective observational study of 57 eyes (56 cases) with clinically diagnosed OSSN, presenting in our center over the past year.

Results: The median age of presentation was 55 years with male:female ratio being 4. Read More

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http://dx.doi.org/10.4103/ijo.IJO_251_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678328PMC
October 2017
12 Reads