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Ear Nose Throat J 2021 Jun 8:1455613211022077. Epub 2021 Jun 8.

Department of Otolaryngology-Head and Neck Surgery, 36897Mackay Memorial Hospital, Taipei.

Thyroglossal duct cysts are typically benign and usually asymptomatic. Malignant transformation is uncommon. Intralaryngeal extension is rare and results in dysphonia or dyspnea. Read More

Front Pediatr 2021 20;9:629009. Epub 2021 May 20.

Department of Otolaryngology Head and Neck Surgery, Beijing Children's Hospital, National Center for Children's Health, Capital Medical University, Beijing, China.

This study was designed to summarize the clinical characteristics, diagnosis and treatment of pharyngeal bronchogenic cysts in children to help in making the correct diagnosis and developing an appropriate treatment plan. The clinical data of 13 children with bronchogenic cysts in the pharynx, who were treated in otolaryngology head and neck surgery department between September 2013 and July 2019, were analyzed retrospectively. The clinical characteristics were evaluated, and the related factors for diagnosis and treatment were analyzed. Read More

Ann Otol Rhinol Laryngol 2021 Jun 4:34894211022233. Epub 2021 Jun 4.

Department of Surgery, Division of Otolaryngology-Head and Neck Surgery, NorthShore University HealthSystem, Evanston, IL, USA.

Objective: The incidence of post-operative glottic cyst (POGC) formation in patients treated with transoral laser microsurgery with potassium-titanyl-phosphate laser (TLM-KTP) photoablation of early glottic carcinoma (EGC) has not previously been described.

Methods: A retrospective chart review was performed to identify all patients with early glottic cancer who underwent with single-modality TLM-KTP at our institution. Each patient received regular follow up with videostroboscopy for tumor surveillance. Read More

J Indian Assoc Pediatr Surg 2021 Mar-Apr;26(2):126-127. Epub 2021 Mar 4.

Department of Pediatric Surgery, Maulana Azad Medical College, New Delhi, India.

The foregut duplication cysts are rare congenital malformation and are usually "solitary" midline noncommunicating mediastinal structures. We present a 2-year-old asymptomatic boy having multiple noncommunicating foregut cysts in the neck as well as the thorax. Read More

Am J Surg Pathol 2021 May 27. Epub 2021 May 27.

Departments of Diagnostic Pathology Medical Oncology Hepatic and Pancreatobiliary Oncology Pediatric Oncology Head and Neck Medical Oncology Division Rare Cancer Center, National Cancer Center Hospital, Tokyo, Japan.

ATF1, CREB1, and CREM, which encode the CREB family of transcription factors, are fused with EWSR1 or FUS in human neoplasms, such as angiomatoid fibrous histiocytoma. EWSR1/FUS-CREB fusions have recently been reported in a group of malignant epithelioid tumors with a predilection to the peritoneal cavity and frequent cytokeratin expression. Here, we studied 8 cytokeratin-positive abdominal malignancies with these fusions for further characterization. Read More

J Cosmet Dermatol 2021 May 27. Epub 2021 May 27.

Department of Pathology, Okmeydanı Training and Research Hospital (Prof Dr Cemil Taşçıoğlu City Hospital), Istanbul, Turkey.

White fibrous papulosis of the neck (WFPN) is a variant of fibroelastolytic papulosis among with pseudoxanthoma elasticum-like papillary dermal elastolysis (PXE-PDE) and papillary dermal elastosis (PDE) which can be considered as an underdiagnosed and/or under reported condition. All the three variants clinically resemble each other while the differentiation is histopathological. Here, we present a case of sudden-onset WFPN on the neck of an elderly female patient, accompanied by the formation of eruptive milia cysts. Read More

BMJ Case Rep 2021 May 25;14(5). Epub 2021 May 25.

Division of Otolaryngology-Head and Neck Surgery, The George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA.

Parathyroid cysts (PCs) are rare pathologies and are typically non-functional (do not secrete parathyroid hormone (PTH)). The aetiology of PCs is highly debated, and management is complex. We present a unique case of a parathyroid adenoma contained within a functional PC and highlight the limitations of intraoperative PTH monitoring during the surgical resection of functional PCs. Read More

Ear Nose Throat J 2021 May 25:1455613211019787. Epub 2021 May 25.

Department of Otolaryngology-Head & Neck Surgery, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.

Dermoid cysts are benign cutaneous neoplasms that contain germ cells from the ectoderm and mesoderm. Approximately 70% are diagnosed during childhood before the age of 5. Although they can present throughout the body, the prevalence is 7% for those arising from the head and neck. Read More

Arch Argent Pediatr 2021 06;119(3):e269-e272

División de Otorrinolaringología, Hospital General de Niños Pedro de Elizalde, Ciudad Autónoma de Buenos Aires.

Branchial cleft anomalies are the second most common congenital head and neck lesions in children. The first congenital head and neck lesion is thyroglossal duct cysts. First branchial cleft anomalies are rare congenital head and neck malformations (8 % of branchial cleft anomalies). Read More

BMJ Case Rep 2021 May 24;14(5). Epub 2021 May 24.

Department of Neurosciences, Faculty of Medicine and Surgery, University of Padova, Padova, Italy.

Epiphora is the first symptom of acquired nasolacrimal duct obstruction (NLDO), which may be due to various causes, including paranasal sinuses and tumours of the nasal cavity. A 28-year-old male patient presented chronic dacryocystitis with left-sided epiphora. Endoscopically, a bulging of the lateral nasal wall at the left-sided agger nasi area was noted. Read More

Am J Otolaryngol 2021 May 19;42(6):103082. Epub 2021 May 19.

Division of Otolaryngology-Head and Neck Surgery, George Washington University School of Medicine & Health Sciences, Washington, DC, United States of America. Electronic address:

Objective: To evaluate the efficacy and safety of ethanol ablation in the treatment of benign head and neck cystic lesions.

Methods: A total of 25 patients who received ethanol ablation (EA) of head and neck cystic lesions by an otolaryngologist at a single institution between October 2017 and October 2020 were identified. Patient demographics, clinical characteristics, treatment details, and treatment outcomes at follow up visits were obtained by retrospective review of electronic medical records. Read More

Pain Med 2021 May 22. Epub 2021 May 22.

Headache Unit, Neurology Department, Hospital Clínico Universitario, Valladolid, Spain.

Background: Nummular Headache (NH) is defined in the International Classification of Headache Disorders (ICHD) by the presence of localized pain circumscribed to a small round area of the scalp, not better accounted by any other diagnosis. As in many other primary headache disorders, secondary cases might occur. To date, 13 secondary cases have been published. Read More

J Int Med Res 2021 May;49(5):3000605211012549

Department of Otolaryngology, The Third People's Hospital of Chengdu, Chengdu, Sichuan, China.

Third branchial cleft cyst is a rare congenital disease of the neck. It presents as a painless mass that develops rapidly in the neck following an infection. This is the first case report of recurrent laryngeal nerve palsy caused by a third branchial cleft cyst. Read More

Niger J Surg 2021 Jan-Jun;27(1):38-41. Epub 2021 Mar 9.

Department of Otorhinolaryngology, Obafemi Awolowo University, Ile-Ife, Nigeria.

Objectives: Thyroglossal duct cyst (TDC) is the most common congenital anterior neck mass in clinical practice. Due to its congenital origin, presentation in adulthood is uncommon with only 7% of cases presenting in this age group. Data are therefore limited on the management of TDC in adults, particularly in Sub-Saharan Africa. Read More

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2021 May;56(5):459-464

Department of Neonatel Intensive Care Unit, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.

To investigate the clinical features, diagnoses and treatments of head and neck occupying lesions in newborns. All newborns with head and neck occupying lesions admitted to Neonatel Intensive Care Unit of the First Affiliated Hospital of Zhengzhou University form January 2014 to November 2019 were included. There were 23 males and 17 females, admission age was from 2 d-28 d, and the clinical manifestations, examinations, treatments and outcomes were evaluated. Read More

Laryngoscope 2021 May 17. Epub 2021 May 17.

Department of Otorhinolaryngology-Head and Neck Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

Objectives/hypothesis: There may be an interobserver variation in the diagnosis of laryngeal disease based on laryngoscopic images according to clinical experience. Therefore, this study is aimed to perform computer-assisted diagnosis for common laryngeal diseases using deep learning-based disease classification models.

Study Design: Experimental study with retrospective data METHODS: A total of 4106 images (cysts, nodules, polyps, leukoplakia, papillomas, Reinke's edema, granulomas, palsies, and normal cases) were analyzed. Read More

Orv Hetil 2021 05 16;162(20):800-805. Epub 2021 May 16.

1 Service d'Orthopédie et Traumatologie Centre Hospitalier Universitaire - Brugmann, Université Libre de Bruxelles, 4, place Van Gehuchten, 1020 Bruxelles, Belgique.

Összefoglaló. A felszínpótló, fém a fémen csípőízületi protézisek reneszánszukat élték a 2000-es években. Elsősorban fiatal, aktív betegek esetében javasolták használni a remélt elméleti előnyök, mint a combfej csontállományának megőrzése, a csípőízület biomechanikájának fenntartása, a luxatio kockázatának csökkentése, a polietilén törmelékek és kopástermékek hiánya miatt. Read More

J Cosmet Dermatol 2021 May 17. Epub 2021 May 17.

Dermatology and Venereology, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt.

Background: Acanthosis nigricans (AN) is a common dermatological issue with several therapeutic modalities to treat. Despite retinoid is the first drug of choice in the treatment, the fractional-ablative carbon dioxide (CO ) laser has revealed as a promising procedure for the management of neck-AN, outstanding to its ability for superficial ablation of the skin surface, with trans-epidermal melanin elimination.

Objectives: To decide whether fractional-ablative CO laser or retinoic acid (5%) peel is the more effective and safe choice for AN treatment. Read More

World J Otorhinolaryngol Head Neck Surg 2021 Apr 24;7(2):71-81. Epub 2021 Jan 24.

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, USA.

Cerebrospinal fluid (CSF) fistulae originating from the fallopian canal of the facial nerve is hypothesized to arise due to atypical patterns of subarachnoid space extension into the geniculate ganglion or more distal regions along the intratemporal course of the facial nerve, but its pathogenesis remains poorly understood. Although a rare etiology of CSF fistulae of the temporal bone, there are significant clinical ramifications due to the risk of recurrent meningitis, difficulty in identifying the anatomic location of the CSF leak, and technical challenges associated with surgical repair. We present three clinical cases of arachnoid cysts within the geniculate fossa with or without CSF fistulization and provide histopathologic correlates of this rare clinical phenomenon from a human temporal bone collection. Read More

Acta Biomed 2021 05 12;92(2):e2021075. Epub 2021 May 12.

Otorhinolaryngology Department, Ramazzini Hospital, Carpi, Italy.

Dermoid cysts (DC) of the head and neck are rare congenital anomalies derived from entrapment of ectodermal cells at lines of fusion in the embryo into mesoderm. We describe a 22-years-old female with an unusual presentation of DC in the subcutaneous tissue of the retro-auricular region, confirmed by pathological examination of the surgically removed specimen. A DC in this region is rare and may be misdiagnosed as a retroauricular lymph node. Read More

Cureus 2021 Apr 11;13(4):e14413. Epub 2021 Apr 11.

Surgical Oncology, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, PAK.

Bronchogenic cysts originate from the tracheobronchial bud, which arises from the embryonic foregut. Congenital bronchogenic cysts in the cervical region, especially in the thyroid or perithyroidal area, are extremely rare. Moreover, distinguishing them from other cervical cystic lesions such as thyroglossal duct and branchial cleft cysts and metastatic cervical lymph nodes is difficult preoperatively. Read More

Sci Rep 2021 May 12;11(1):10147. Epub 2021 May 12.

Department of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical Center Taipei, No. 325, Sec. 2, Cheng-Gong Road, Neihu District, Taipei, 114, Taiwan, Republic of China.

Laryngoscopes are widely used in the clinical diagnosis of laryngeal lesions, but such diagnosis relies heavily on the physician's subjective experience. The purpose of this study was to develop a computer-aided diagnostic system for the detection of laryngeal lesions based on objective criteria. This study used the distinct features of the image contour to find the clearest image in the laryngoscopic video. Read More

Case Rep Oncol 2021 Jan-Apr;14(1):561-567. Epub 2021 Mar 22.

Pathology and Anatomy Department, Airlangga University, Surabaya, Indonesia.

Schwannomas are the most common peripheral nerve sheath tumors. Benign schwannomas with malignant transformation are rarely reported. Most common schwannomas occur in the head and neck region. Read More

BMJ Case Rep 2021 May 7;14(5). Epub 2021 May 7.

Orthopaedics, AIIMS, Bhubaneswar, Orissa, India.

Access to the cystic lesion of the talar body without damage to the articular surface is difficult. This case report is about a 23-year-old man who had a symptomatic huge cystic lesion in the left-sided talus bone. Radiograph and CT scan showed an expansile lytic lesion within the talar body. Read More

Clin Ter 2021 May;172(3):175-178

University of Rome "La Sapienza"Maxillofacial departement, St. Andrea Hospital, Rome, Italy.

Abstract: Branchiogenic carcinoma (BC) is an extremely rare and still controversial clinic entity with few cases reported in literature. This malignant squamous epithelial wall degeneration of a pre-existing second branchial cleft cyst (SBCC) was first described by Von Volk-mann in 1882. Here we present a case of cervical cystic mass that was histologically diagnosed as a primary branchial cleft cyst carcinoma. Read More

Pol Merkur Lekarski 2021 Apr;49(290):153-157

3Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Italy.

The greatest challenge of modern implantology is the loss of bone tissue in esthetic region of maxilla and mandible. Significant bone changes caused for example by cysts, unerupted teeth or traumatic extraction often provoke bilateral or trilateral bone defects. Thanks to the possibility of applying demineralized dentin and dentin blocks gained from extracted teeth of the patient, it is possible to successfully regenerate bone tissue especially in the esthetic zone. Read More

BMJ Case Rep 2021 Apr 22;14(4). Epub 2021 Apr 22.

Radiology Department, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisboa, Portugal

We report the case of a 25-year-old man with a maxillary ghost cell odontogenic carcinoma (GCOC). The patient presented to the maxillofacial and head and neck surgery clinic with a growing lump in the left maxilla. Initial workup with CT revealed a cystic lesion in the left upper jaw with associated bone erosion and an enhancing soft-tissue component. Read More

Histopathology 2021 Apr 21. Epub 2021 Apr 21.

Department of Dermatology, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.

Background: Fibrous cephalic plaques (FCPs) in individuals with tuberous sclerosis complex (TSC) may be excised for cosmetic reasons or biopsied to confirm lesion identification and TSC diagnosis.

Aim: To determine the range of histopathological features of FCPs.

Methods: A retrospective analysis was conducted on 119 adults with TSC. Read More

Head Neck Pathol 2021 Apr 21. Epub 2021 Apr 21.

Department of Pathology, Naval Medical Center San Diego, 34800 Bob Wilson Drive, San Diego, CA, 92134-5000, USA.

Dentigerous cysts, also known as follicular cysts, are among the most common developmental cysts of the gnathic bones. The majority of cases are clinically asymptomatic and discovered incidentally on panographic radiographs during routine dental care. The cyst appears as a radiolucency, classically unilocular, associated with the crown of an unerupted or impacted tooth. Read More

Cureus 2021 Mar 17;13(3):e13940. Epub 2021 Mar 17.

Department of Otolaryngology, Ear, Nose and Throat (ENT) South, Dothan, USA.

Branchial cleft cysts are congenital anomalies which develop in utero, most commonly arising from the second branchial cleft. They are often asymptomatic lateral neck masses but can enlarge and become symptomatic in the setting of infection. The cystic cavity can form a potential space which can harbor infection and, in rare cases, malignant spread of primary tumors. Read More