322,126 results match your criteria Near Drowning
Chemosphere 2018 Dec 10;219:538-545. Epub 2018 Dec 10.
Jilin Institute of Chemical Technology, Jilin, 132022, China. Electronic address:
In this study, the pollution status and the ecological risks of heavy metals (Cu, Zn, Pb, Ni and Cr) in the sediments of the Songhua River in an urban area with petrochemical industries were assessed. The highest mean concentration of total heavy metals occurred in the freezing period, and the highest total heavy metal concentrations were observed near the petrochemical industrial area. The geo-accumulation index indicated that Cu was the most contaminated heavy metal. Read More
Micron 2018 Nov 23;118:9-21. Epub 2018 Nov 23.
Biomedical Research Institute, National Institute of Industrial Science and Technology (AIST), Higashi 1-1-1, Tsukuba, Ibaraki, 305-8566, Japan. Electronic address:
Neural networking, including axon targeting and synapse formation, is the basis of various brain functions, including memory and learning. Diabetes-mellitus affects peripheral nerves and is known to cause fatty liver disease. Electron microscopy (EM) provides the resolution required to observe changes in fine subcellular structures caused by such physiological and pathological processes, but samples are observed in vacuum. Read More
Clin Neurol Neurosurg 2018 Dec 7;176:89-96. Epub 2018 Dec 7.
Departament of Neurology, Laboratory of Molecular and Cellular Biology, LIM15, Faculdade de Medicina, Universidade de São Paulo, SP, Brazil.
Meningiomas, tumors that originate from meningothelial cells, account for approximately 30% of all new diagnoses of central nervous system neoplasms. According to the 2016 WHO classification of central nervous system tumors meningiomas are classified into three grades: I, II, and III. Past studies have shown that the risk of meningiomas recurrence is strongly correlated with the molecular profile of the tumor. Read More
Eur J Med Chem 2018 Dec 5;163:546-559. Epub 2018 Dec 5.
Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur, 208016, UP, India. Electronic address:
Near-infrared (NIR) Ytterbium(ΙΙΙ) complexes namely [Yb(dpq)(DMF)Cl] (1), [Yb(dppz)(DMF)Cl] (2), [Yb(dpq)(ttfa)] (3) and [Yb(dppz)(ttfa)] (4) based on photosensitizing antenna: dipyrido-[3,2-d:2',3'-f]-quinoxaline (dpq), dipyrido-[3,2-a:2',3'-c]-phenazine (dppz) and 4,4,4-trifluoro-1-(2-thienyl)-1,3-butanedione (Httfa), were designed as NIR bioimaging agents utilizing cooperative upconversion luminescence (CUCL) of Yb(III). Their structures, detailed photophysical properties, biological interactions, photo-induced DNA cleavage, NIR photocytotoxicity and cellular internalization and bioimaging properties were examined. Discrete mononuclear complexes adopt a seven-coordinated {LnNOCl} mono-capped octahedron (1, 2) and eight-coordinated {LnNO} distorted square antiprism geometry (3, 4) with bidentate N, N-donor dpq, dppz and O,O-donor ttfa ligands. Read More
J Colloid Interface Sci 2018 Dec 5;538:605-610. Epub 2018 Dec 5.
MESA+ Institute for Nanotechnology & Faculty of Science and Technology, University of Twente, PO Box 217, 7500 AE Enschede, the Netherlands. Electronic address:
Hypothesis: The stability of colloidal suspensions can be influenced by supersaturation of the supporting electrolyte with gas. It has been proposed that this effect can be attributed to the formation of nanobubbles on the surface of the colloidal particles, in turn influencing DLVO forces. While previous interpretations have focused primarily on van der Waals interactions, probing positively charged particles can provide complementary insight into electrostatic interactions. Read More
Bioresour Technol 2018 Dec 10;274:459-467. Epub 2018 Dec 10.
Department of Biology, Lakehead University, Ontario P7B 5E1, Canada. Electronic address:
Based on a general understanding that hemicellulose removal is more efficient than delignification for biomass deconstruction, an Aspergillus niger strain producing high xylanase activity was screened out from seventeen strains by clear halo experiments. Low-cost enzyme cocktail with high xylanase activity was produced from wheat straw medium fermented by the Gyx086 strain. The enzyme cocktail with high xylanase activity could more effectively hydrolyze wheat straw than other biomasses. Read More
J Control Release 2018 Dec 12. Epub 2018 Dec 12.
Department of Civil & Environmental Engineering, Hanyang University, 222 Wangsimni-Ro, Seoul 04763, Republic of Korea. Electronic address:
The incorporation of nanotechnology as a means for nanopesticides is in the early stage of development. The main idea behind this incorporation is to lower the indiscriminate use of conventional pesticides to be in line with safe environmental applications. Nanoencapsulated pesticides can provide controlled release kinetics, while efficiently enhancing permeability, stability, and solubility. Read More
Am J Ophthalmol 2018 Dec 12. Epub 2018 Dec 12.
Department of Ophthalmology, Tokyo Dental Collage Suidobashi Hospital.
Purpose: To evaluate the binocular visual function and depth of focus after staged implantation of diffractive multifocal intraocular lenses (MIOLs) with three different add powers following cataract removal.
Design: Prospective comparative case series.
Methods: Setting: Institutional. Read More
Swiss Med Wkly 2018 Nov 2;148:w14688. Epub 2018 Dec 2.
Health Ethics and Policy Lab, Department of Health Sciences and Technology, ETH Zurich, Switzerland.
Dual use research of concern (DURC) is defined by the World Health Organization as "life sciences research that is intended for benefit, but which might easily be misapplied to do harm." Ethical and policy discussions on DURC span the past three decades. Today, however, new and emerging technologies and associated sociocultural transformations within the scientific community are reshaping the current risk scenario. Read More
Pacing Clin Electrophysiol 2018 Dec 15. Epub 2018 Dec 15.
Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma, Omiya-ku, Saitama City, Saitama, Japan.
J Comp Neurol 2018 Dec 15. Epub 2018 Dec 15.
Department of Pediatrics, School of Medicine, UC Davis, Davis, CA.
Cortical proliferative zones have been studied for over 100 years, yet recent data has revealed that microglial cells constitute a sizeable proportion of ventricular zone cells during late stages of cortical neurogenesis. Microglia begin colonizing the forebrain after neural tube closure and during later stages of neurogenesis populate regions of the developing cortex that include the proliferative zones. We previously showed that microglia regulate the production of cortical cells by phagocytosing neural precursor cells (NPCs), but how microglia interact with NPCs remains poorly understood. Read More
Cerebellum 2018 Dec 14. Epub 2018 Dec 14.
Department of Neurology, Ludwig-Maximilians University, Marchioninistrasse 15, 81377, Munich, Germany.
The differential diagnosis of vertigo or dizziness as a result of cerebellar disorders can be difficult as many patients with a cerebellar pathology do not present with the full spectrum of cerebellar signs. The main goal of this study was to describe the typical clinical features of these patients with vertigo or dizziness of a cerebellar origin. We reviewed the medical records of 5400 patients with vertigo and dizziness from our tertiary outpatient clinic for vertigo and balance disorders. Read More
Ann Biomed Eng 2018 Dec 14. Epub 2018 Dec 14.
UNSW Sydney, Sydney, NSW, Australia.
Prior numerical studies have shown that the blood flow patterns surrounding drug-eluting stents can enhance drug uptake in stented arteries. However, these studies employed steady-state simulations, wherein flow and drug transport parameters remained constant with respect to time. In the present study, numerical simulations and in-vitro experiments were performed to determine whether luminal blood flow patterns can truly enhance drug uptake in stented arteries. Read More
Eur Phys J E Soft Matter 2018 Dec 5;41(12):140. Epub 2018 Dec 5.
Duke University, Mechanical Engineering and Materials Science Dept., Durham, NC, USA.
Experiments with evaporation of capillary bridges between two glass spheres show that the bridge gorge radius decreases much faster than the contact radius, distorting the original constant mean curvature bridge shape. In addition, the Laplace pressure calculated from local principal curvatures exhibits high gradients along the bridge moving external surface, most commonly with a high suction near the triple phase contact and positive pressure near the gorge. The high suction results from a negative external curvature at contact. Read More
Nat Commun 2018 Dec 14;9(1):5326. Epub 2018 Dec 14.
National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, People's Republic of China.
Alphaviruses are enveloped RNA viruses that contain several human pathogens. Due to intrinsic heterogeneity of alphavirus particles, a high resolution structure of the virion is currently lacking. Here we provide a 3. Read More
Nat Commun 2018 Dec 14;9(1):5332. Epub 2018 Dec 14.
Department of Chemical Engineering and Applied Chemistry, University of Toronto, 200 College Street, Toronto, ON, M5S 3E5, Canada.
Metabolism is highly regulated, allowing for robust and complex behavior. This behavior can often be achieved by controlling a small number of important metabolic reactions, or metabolic valves. Here, we present a method to identify the location of such valves: the metabolic valve enumerator (MoVE). Read More
Plant Physiol 2018 Dec 14. Epub 2018 Dec 14.
The Pennsylvania State University CITY: University Park STATE: Pennsylvania POSTAL_CODE: n/a United States Of America [US]
Synechococcus elongatus UTEX 2973 (Synechococcus 2973) has the shortest reported doubling time (2.1 h) among cyanobacteria, making it a promising platform for the solar-based production of biochemicals. In this meta-analysis, its intracellular flux distribution was re-computed using genome-scale Isotopic Non-Stationary-13C-Metabolic Flux Analysis (INST-MFA) given the labeling dynamics of 13 metabolites reported in an earlier study. Read More
Appl Environ Microbiol 2018 Dec 14. Epub 2018 Dec 14.
The Australian Wine Research Institute, PO Box 197, Glen Osmond, Adelaide, South Australia, 5064, Australia.
SO addition is practiced in the wine industry to mitigate the risk of microbial spoilage and to extend wine shelf-life. Generally, this strategy does not interfere with primary alcoholic fermentation as wine strains of exhibit significant SO tolerance, largely driven by the efflux pump Ssu1p. One of the key yeast species responsible for wine spoilage is , which also exhibits strain-dependent SO tolerance, although this occurs via unknown mechanisms. Read More
J Neurointerv Surg 2018 Dec 14. Epub 2018 Dec 14.
Institute of Neurological Sciences, Prince of Wales Hospital, Randwick, New South Wales, Australia.
Background: The Pipeline Embolisation Device with Shield technology (PED-Shield) is suggested to have reduced thrombogenicity. This reduced thrombogenicity may make it possible to use safely in the acute treatment of aneurysmal subarachnoid haemorrhage (aSAH) on single antiplatelet therapy (SAPT).
Objective: To evaluate the safety and efficacy of the off-label use of PED-Shield with SAPT for the acute treatment of aSAH. Read More
RNA 2018 Dec 14. Epub 2018 Dec 14.
University of California Santa Cruz
Protein synthesis in all organisms proceeds by stepwise translocation of the ribosome along messenger RNAs (mRNAs), during which the helicase activity of the ribosome unwinds encountered structures in the mRNA. This activity is known to occur near the mRNA tunnel entrance, which is lined by ribosomal proteins uS3, uS4, and uS5. However, the mechanism(s) of mRNA unwinding by the ribosome and the possible role of these proteins in the helicase activity are not well understood. Read More
JMIR Res Protoc 2018 Dec 14;7(12):e10777. Epub 2018 Dec 14.
Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, CA, United States.
Background: Advancing technology has increased functionality and permitted more complex study designs for behavioral interventions. Investigators need to keep pace with these technological advances for electronic data capture (EDC) systems to be appropriately executed and utilized at full capacity in research settings. Mobile technology allows EDC systems to collect near real-time data from study participants, deliver intervention directly to participants' mobile devices, monitor staff activity, and facilitate near real-time decision making during study implementation. Read More
Lancet Respir Med 2018 Dec 11. Epub 2018 Dec 11.
Division of Respiratory Medicine, National Institute for Health Research, Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, UK. Electronic address:
Background: Few genetic studies that focus on moderate-to-severe asthma exist. We aimed to identity novel genetic variants associated with moderate-to-severe asthma, see whether previously identified genetic variants for all types of asthma contribute to moderate-to-severe asthma, and provide novel mechanistic insights using expression analyses in patients with asthma.
Methods: In this genome-wide association study, we used a two-stage case-control design. Read More
Am J Emerg Med 2018 Dec 7. Epub 2018 Dec 7.
Trauma Program, Department of Pediatric Surgery, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43205, United States of America; Center for Pediatric Trauma Research, The Research Institute at Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43205, United States of America; The Ohio State University College of Medicine, 370 West 9(th) Avenue, Columbus, OH 43210, United States of America. Electronic address:
Background: Adolescent trauma patients are reported to have increased incidence of alcohol and other drug (AOD) use, but previous studies have included inadequate screening of the intended populations. A Level 1 Pediatric Trauma Center achieved a 94% rate of AOD screening. We hypothesized that a positive AOD screening result is associated with males, increasing age, lower socioeconomic status, violent injury mechanism, higher Injury Severity Score (ISS), lower GCS, need for operation and increased hospital length of stay. Read More
Biochem Biophys Res Commun 2018 Dec 11. Epub 2018 Dec 11.
Department of Medical Physics, Graduate School of Medicine, Tohoku University, Sendai, Miyagi, 980-8575, Japan. Electronic address:
Previous studies showed that gold nanoparticles (AuNPs) are useful radiosensitizers which optimize radiation therapy under low-dose radiation. However, the mechanisms of AuNP radiosensitization, including the amount and localization of the AuNPs interacting with cancer cells, has not yet been quantified. To answer these questions, we prepared AuNPs conjugated with anti-human epidermal growth factor receptor type 2 (HER2) antibody via polyethylene glycol (PEG) chains (AuNP-PEG-HER2ab). Read More
Environ Int 2018 Dec 11. Epub 2018 Dec 11.
Department of Biostatistics and Epidemiology, College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Background: Natural gas drilling may pose multiple health risks, including congenital anomalies, through air pollutant emissions and contaminated water. Two recent studies have evaluated the relationship between natural gas activity and congenital anomalies, with both observing a positive relationship.
Objectives: We aimed to evaluate whether residence near natural gas wells is associated with critical congenital heart defects (CCHD), neural tube defects (NTD), and oral clefts in Oklahoma, the third highest natural gas producing state in the US. Read More
Molecules 2018 Dec 13;23(12). Epub 2018 Dec 13.
Faculty of Pharmacy, AIMST University, Semeling 8100, Bedong, Kedah, Malaysia.
In the present study, we have developed a green approach for the synthesis of silver nanoparticles (DSAgNPs) using aqueous extract of seed and determined its antibacterial, photocatalytic and cytotoxic effects. Surface plasmon resonance confirmed the formation of DSAgNPs with a maximum absorbance (λ) of 420 nm. SEM and TEM images revealed DSAgNPs were spherical and rod shaped, with a size range of 20 nm and 75 nm. Read More
Brain Sci 2018 Dec 13;8(12). Epub 2018 Dec 13.
Evidence-Based Therapeutics Group, Department of Clinical Pharmacology, Universidad de La Sabana, Chía 140013, Colombia.
Genetics has led to a new focus regarding approaches to the most prevalent diseases today. Ascertaining the molecular secrets of neurodegenerative diseases will lead to developing drugs that will change natural history, thereby affecting the quality of life and mortality of patients. The sequencing of candidate genes in patients suffering neurodegenerative pathologies is faster, more accurate, and has a lower cost, thereby enabling algorithms to be proposed regarding the risk of neurodegeneration onset in healthy persons including the year of onset and neurodegeneration severity. Read More
Biomed Pharmacother 2019 Jan 13;109:1445-1453. Epub 2018 Nov 13.
Department of Geratology, The Second Hospital of Tianjin Medical University, PR China. Electronic address:
Introduction: We have investigated the possible effects and mechanism of atorvastatin, a statin, and/or probucol, a powerful antioxidant used to lower cholesterol before 1995, on the atherosclerosis development.
Methods: Apolipoprotein-E-deficient (ApoE) mice fed with the high fat diet were randomly divided into 3 groups (n = 10/each group): Placebo, Atorvastatin (10 mg/ kg/d), and atorvastatin (10 mg/kg/d) plus probucol (10 mg/kg/d) groups. C57BL/6 J mice were fed with normal diet as the control group (n = 10). Read More
Colloids Surf B Biointerfaces 2019 Jan 23;173:833-841. Epub 2018 Oct 23.
State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, People's Republic of China. Electronic address:
Titanium and its alloys are widely used in many clinical applications, but implant-associated infection may lead to implant failure. Because of the increasing concern about antibiotic resistant pathogen, photothermal therapy (PTT) as a new treatment strategy has received considerable attention. In this work, gold nanorods (GNRs) photoexcited by the near-infrared (NIR) light were immobilized on Ti surface by electrostatic surface self-assembly technique. Read More
Nihon Rinsho 2016 Dec;74(12):2003-2007
Crimean-Congo hemorrhagic fever (CCHF), caused by infection with CCHF virus (CCHFV), is viral hemorrhagic fever with high case fatality rate. CCHFV is classified to Family Bunyaviridae, Genus Nairovirus. CCHF is endemic to Africa, Eastern Europe, the Middle East, central Asia, and southern Asia. Read More
Nat Prod Commun 2017 Mar;12(3):431-434
The chemical composition of the essential oil (EO), microwave extract (ME) and hydrolate extract (HE) from the same batch of leaves of Fortunella japonica, was investigated: by combination of chromatographic (GC, CC) and spectroscopic techniques (GC-MS, 13C NMR). F. japonica essential oil and extracts are complex mixtures of 28-60 compounds being mainly oxygenated sesquiterpenes. Read More
Biomaterials 2018 Dec 10;193:12-21. Epub 2018 Dec 10.
CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing 100190, PR China. Electronic address:
Nanosized drug delivery systems (nDDS) have been extensively exploited to achieve improved therapeutic performance of chemotherapeutic drugs in cancer treatment. Carrier-free nanodrugs have recently emerged as a promising generation of nDDS. In this work, a carrier-free theranostic nanodrug was fabricated by incorporating near-infrared (NIR) emission AIEgens (NPAPF) with redox responsive camptothecin-gemcitabine amphiphilic prodrug (CPT-ss-GEM) to form self-assembled nanoparticles (NCssG NPs). Read More
Biomaterials 2018 Dec 10;193:1-11. Epub 2018 Dec 10.
Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China; Department of Physics and Materials Science, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, China. Electronic address:
Mild heat stimulation can promote the restoration of bone defects but unfortunately, the delivery of exo-hyperthermy into human body is not efficient enough. In this study, mild heat-induced osteogenesis with high efficacy is demonstrated on an osteoimplant composed of black phosphorus nanosheets and poly(lactic-co-glycolic acid) (BPs@PLGA) with the participation of near-infrared (NIR) light irradiation. BPs@PLGA with only 0. Read More
Eur J Pharm Biopharm 2018 Dec 11. Epub 2018 Dec 11.
CAS Key Laboratory of Soft Matter Chemistry, Hefei National Laboratory for Physical Sciences at the Microscale, and Department of Chemical Physics, iCHEM, University of Science and Technology of China, Jinzai road 96, Hefei,230026, Anhui, China. Electronic address:
Efficient delivery of hydrophobic photosensitizer (PS) into tumor cells is a key step for photodynamic therapy (PDT). Redox-responsive polymeric nanoparticles of amphiphilic macro-photosensitizer has designed and prepared as a prodrug-like pro-photosensitizer (pro-PS) for PDT. PEG works as the hydrophilic block and the near infrared (NIR) brominated BODIPY derivative (BDP) works as the hydrophobic PS, and they were linked via the disulfide bond as PEG-SS-BDP, which could be broken for drug release owing to the high GSH concentration inside tumor cells. Read More
Sci Total Environ 2018 Dec 5;657:391-400. Epub 2018 Dec 5.
Department of Agricultural, Food and Forestry Systems (GESAAF), Università degli Studi di Firenze, Florence, Italy. Electronic address:
Advection fog is the sole source of water for many near-the-sea arid areas worldwide such as the lomas, i.e. fog-dependant landscapes of the coastal zone of Peru and Northern Chile, where deforestation occurred since 16th century, leading to a progressive and severe desertification. Read More
Anal Biochem 2018 Dec 11. Epub 2018 Dec 11.
Key Lab of Process Analysis and Control of Sichuan Universities, Yibin University, Yibin, Sichuan, 644000, China. Electronic address:
The feasibility of using near-infrared (NIR) spectroscopy coupled with classifier ensemble for improving the diagnosis of colorectal cancer was explored. A total of 157 NIR spectra from the patients were recorded and partitioned into the training set and the test set. Four algorithms, i. Read More
J Craniofac Surg 2018 Dec 13. Epub 2018 Dec 13.
UT Southwestern Medical Center.
Human interactions begin with near-instantaneous visual evaluation of the face, modifying emotional responses and social behavior toward the person. Eye-tracking technology can provide a potential window into how humans undertake this evaluation, and the threshold of whether a face containing a craniofacial difference is perceived as "normal." This study's main questions were whether gaze patterns differ from normal when evaluating children with craniofacial differences, and whether these gaze patterns vary with different levels of craniofacial deformity. Read More
Arch Pathol Lab Med 2018 Dec 14. Epub 2018 Dec 14.
From the Departments of Pathology (Dr Dintzis) and Surgery (Ms Hales and Drs Calhoun, Javid, and Byrd), University of Washington Medical Center, Seattle; Breast Surgery Clinic (Dr Harrington), Department of Pathology (Dr Tan), and Clinical Trials (Mses Fortney and Porenta), Overlake Hospital Medical Center, Bellevue, Washington; Development (Dr Miller), Clinical Operations (Mses Ishak and Gombotz), Research (Ms Hansen and Dr Parrish-Novak), and Device Development (Dr Kittle and Mr Perry), Blaze Bioscience, Inc., Seattle, Washington; and the Department of Surgery, University of Washington, Seattle (Dr Anderson).
Context.—: Resection of breast carcinoma with adequate margins reduces the risk of local recurrence and reoperation. Tozuleristide (BLZ-100) is an investigational peptide-fluorophore agent that may aid in intraoperative tumor detection and margin assessment. Read More
Pol J Microbiol 2018 ;67(4):525-528
Department of Biophysics, Faculty of Medicine, Near East University , Nicosia , Cyprus.
Hepatitis E virus (HEV) is transmitted by a fecal oral route from animals to humans following exposure to the body fluids of infected animals. We investigated the seroprevalence of anti-hepatitis E (anti-HEV) antibodies by monitoring IgG and IgM virus antibodies amongst employees in the animal industry in North Cyprus through a cross-sectional study. Samples were taken from individuals without occupational exposure to animals and from those who worked with animals (doing animal husbandry, veterinary work or butchery). Read More
Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Jul;32(14):1051-1055
Department of Otolaryngology, Sun Yat-sen Memorial Hospital,Sun Yat-sen University, Guangzhou, 510120, China.
To evaluate the feasibility, effectiveness and safety of robot-assisted transaxillary thyroidectomy (RATT). The clinical data of 66 patients undergoing RATT from November 2016 to May 2018 were prospectively collected and analyzed. The average age was (38. Read More
J Biomed Opt 2018 Dec;23(12):1-11
711th Human Performance Wing, Airman Systems Directorate, Bioeffects Division, Optical Radiation Bio, United States.
Skin injury response to near-infrared (NIR) laser radiation between the minimum visible lesion threshold and ablation onset is not well understood. This study utilizes a 1070-nm diode-pumped Yb-fiber laser to explore the response of excised porcine skin to high-energy exposures in the suprathreshold injury region without inducing ablation. Concurrent high-speed videography is employed to determine a dichotomous response for three progressive damage categories: observable surface distortion, surface bubble formation due to contained intracutaneous water vaporization, and surface bubble rupture during exposure. Read More
Korean J Ophthalmol 2018 Dec;32(6):483-487
Department of Ophthalmology, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea.
Purpose: To compare the characteristics and surgical outcomes in patients with tenacious proximal fusion (TPF) and high accommodative convergence/accommodation ratio (AC/A) types of intermittent exotropia.
Methods: This study retrospectively enrolled 40 patients with intermittent exotropia, 23 with TPF and 17 with high AC/A. Binocular function was evaluated by Worth's 4-dot test. Read More
Head Neck 2018 Dec 14. Epub 2018 Dec 14.
Department of Oral and Maxillofacial Surgery, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, China.
Background: The study aimed to define indocyanine green (ICG) kinetics to determine the optimal ICG dose and surgical time for near-infrared fluorescence-guided oral cancer surgery.
Methods: Spectrometer and grayscale digital imaging were used to quantify the ICG kinetics in 12 patients with oral cancer. The fluorescence intensity and signal-to-background ratio (SBR) of tumor and normal tissue were tested at 1, 6, and 24 hours after ICG injection. Read More
Head Neck 2018 Dec 14. Epub 2018 Dec 14.
Department of Otorhinolaryngology and Head and Neck Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.
Background: Surgical treatment of cancer requires tumor excision with emphasis on function preservation which is achieved in (early stage) laryngeal cancer by transoral carbon dioxide (CO ) laser surgery. Whereas conventional laser surgery is restricted by the surgeon's visual recognition of tumor tissue, new approaches based on fluorescence-guided surgery (FGS) improve the detection of the tumor and its margin. However, it is unclear whether fluorophores are compatible with high-power laser application or whether precision is compromised by laser-induced bleaching of the dye. Read More
Adv Mater 2018 Dec 14:e1805656. Epub 2018 Dec 14.
Department of Physics, Southern University of Science and Technology, Shenzhen, 518055, China.
2D atomic sheets of transition metal dichalcogenides (TMDs) have a tremendous potential for next-generation optoelectronics since they can be stacked layer-by-layer to form van der Waals (vdW) heterostructures. This allows not only bypassing difficulties in heteroepitaxy of lattice-mismatched semiconductors of desired functionalities but also providing a scheme to design new optoelectronics that can surpass the fundamental limitations on their conventional semiconductor counterparts. Herein, a novel 2D h-BN/p-MoTe /graphene/n-SnS /h-BN p-g-n junction, fabricated by a layer-by-layer dry transfer, demonstrates high-sensitivity, broadband photodetection at room temperature. Read More
Hepatology 2018 Dec 14. Epub 2018 Dec 14.
University of Michigan.
Background/aim: Monotherapy with interferon or nucleoside analog is generally not recommended during the immune tolerant (IT) phase of chronic hepatitis B virus (HBV) infection. Recognition that high HBV DNA levels are associated with hepatocellular carcinoma has increased interest in treating HBV in the IT phase. Small pediatric studies reported efficacy with combination nucleoside analog and interferon therapy. Read More
Asian J Endosc Surg 2018 Dec 13. Epub 2018 Dec 13.
Department of Gastrointestinal Surgery, St. Luke's International Hospital, Tokyo, Japan.
We performed laparoscopic surgery for three cases of colorectal cancer using an 8K ultra-high-definition endoscopic system, which offers 16-fold higher resolution than the current 2K high-definition endoscope. The weight of the camera has been successfully reduced to 370 g. To maximize the advantages of the 8K ultra-high-definition endoscope, surgery was performed by darkening the room and placing a large 85-in. Read More
Asian J Endosc Surg 2018 Dec 13. Epub 2018 Dec 13.
Department of Obstetrics and Gynecology, School of Medicine, Keio University, Tokyo, Japan.
Introduction: Laparoscopic surgery is a minimally invasive surgery, and the rate of postoperative adhesions is low. Although Seprafilm® helps to reduce adhesions, its application in the abdominal cavity during laparoscopic surgery is difficult because of its material. Therefore, we propose an easy method for applying this adhesion barrier. Read More
Neurogastroenterol Motil 2018 Dec 14:e13518. Epub 2018 Dec 14.
Laboratory of Physiology, Department of Basic Veterinary Science, The United Graduate School of Veterinary Sciences, Gifu University, Gifu, Japan.
Background: Esophageal peristalsis is controlled by the brainstem via vago-vagal reflex. However, the precise regulatory mechanisms in the striated muscle portion are largely unknown. The aim of this study was to characterize peristaltic motility in the portion of the esophagus using a novel in vivo method in rats. Read More
Congenit Heart Dis 2018 Dec 13. Epub 2018 Dec 13.
The Heart Center, Nationwide Children's Hospital, Columbus, Ohio.
Objective: We sought to describe the leaflet morphology variation in the Melody Transcatheter Pulmonary Valve (TPV) and evaluate associated outcomes. The Melody TPV is constructed from harvested bovine jugular venous valves which have been rigorously tested. Natural anatomic leaflet variations are seen in the Melody TPV but have not been evaluated. Read More