2,166 results match your criteria Nature Reviews Microbiology [Journal]


Publisher Correction: Host and viral determinants of influenza A virus species specificity.

Nat Rev Microbiol 2018 Dec 18. Epub 2018 Dec 18.

Department of Medicine, Imperial College London, London, UK.

In Figure 4, seasonal influenza virus was erroneously indicated as having "HA α2-3 SA preference" instead of "HA drift from population immunity" to represent ongoing evolution of seasonal influenza virus. This has now been corrected in all versions of the Review. The publisher apologizes to the authors and to readers for this error. Read More

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http://dx.doi.org/10.1038/s41579-018-0140-yDOI Listing
December 2018

Reprogramming by persisters.

Authors:
Andrea Du Toit

Nat Rev Microbiol 2018 Dec 18. Epub 2018 Dec 18.

Nature Reviews Microbiology, .

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http://dx.doi.org/10.1038/s41579-018-0143-8DOI Listing
December 2018

Supporting gut epithelial regeneration.

Authors:
Andrea Du Toit

Nat Rev Microbiol 2018 Dec 18. Epub 2018 Dec 18.

Nature Reviews Microbiology, .

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http://dx.doi.org/10.1038/s41579-018-0144-7DOI Listing
December 2018

Living without the cell wall.

Authors:
Andrea Du Toit

Nat Rev Microbiol 2018 Dec 18. Epub 2018 Dec 18.

Nature Reviews Microbiology, .

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http://dx.doi.org/10.1038/s41579-018-0142-9DOI Listing
December 2018

Fusobacterium nucleatum - symbiont, opportunist and oncobacterium.

Nat Rev Microbiol 2018 Dec 13. Epub 2018 Dec 13.

Harvard T. H. Chan School of Public Health, Boston, MA, USA.

Fusobacterium nucleatum has long been found to cause opportunistic infections and has recently been implicated in colorectal cancer; however, it is a common member of the oral microbiota and can have a symbiotic relationship with its hosts. To address this dissonance, we explore the diversity and niches of fusobacteria and reconsider historic fusobacterial taxonomy in the context of current technology. We also undertake a critical reappraisal of fusobacteria with a focus on F. Read More

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http://dx.doi.org/10.1038/s41579-018-0129-6DOI Listing
December 2018

A rainbow of influenza virions.

Authors:
Ursula Hofer

Nat Rev Microbiol 2018 Dec 13. Epub 2018 Dec 13.

Nature Reviews Microbiology, .

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http://dx.doi.org/10.1038/s41579-018-0135-8DOI Listing
December 2018
1 Read

Dissolving immune cell membranes.

Authors:
Ashley York

Nat Rev Microbiol 2018 Dec 12. Epub 2018 Dec 12.

Nature Reviews Microbiology, .

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http://dx.doi.org/10.1038/s41579-018-0139-4DOI Listing
December 2018
1 Read

Buckling under stress.

Authors:
Ashley York

Nat Rev Microbiol 2018 Dec 12. Epub 2018 Dec 12.

Nature Reviews Microbiology, .

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http://dx.doi.org/10.1038/s41579-018-0137-6DOI Listing
December 2018
1 Read

Can we predict keystones?

Nat Rev Microbiol 2018 Dec 12. Epub 2018 Dec 12.

KU Leuven Department of Microbiology and Immunology, Rega Institute, Laboratory of Molecular Bacteriology, Leuven, Belgium.

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http://dx.doi.org/10.1038/s41579-018-0132-yDOI Listing
December 2018

Reply to 'Can we predict microbial keystones?'

Nat Rev Microbiol 2018 Dec 11. Epub 2018 Dec 11.

Plant-Soil Interactions, Department of Agroecology and Environment, Agroscope, Reckenholz, Zürich, Switzerland.

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http://dx.doi.org/10.1038/s41579-018-0133-xDOI Listing
December 2018

Fungal secondary metabolism: regulation, function and drug discovery.

Authors:
Nancy P Keller

Nat Rev Microbiol 2018 Dec 10. Epub 2018 Dec 10.

Department of Medical Microbiology and Immunology, Department of Bacteriology, University of Wisconsin-Madison, Madison, WI, USA.

One of the exciting movements in microbial sciences has been a refocusing and revitalization of efforts to mine the fungal secondary metabolome. The magnitude of biosynthetic gene clusters (BGCs) in a single filamentous fungal genome combined with the historic number of sequenced genomes suggests that the secondary metabolite wealth of filamentous fungi is largely untapped. Mining algorithms and scalable expression platforms have greatly expanded access to the chemical repertoire of fungal-derived secondary metabolites. Read More

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http://dx.doi.org/10.1038/s41579-018-0121-1DOI Listing
December 2018

Origin and evolution of pathogenic coronaviruses.

Nat Rev Microbiol 2018 Dec 10. Epub 2018 Dec 10.

CAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, China.

Severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) are two highly transmissible and pathogenic viruses that emerged in humans at the beginning of the 21st century. Both viruses likely originated in bats, and genetically diverse coronaviruses that are related to SARS-CoV and MERS-CoV were discovered in bats worldwide. In this Review, we summarize the current knowledge on the origin and evolution of these two pathogenic coronaviruses and discuss their receptor usage; we also highlight the diversity and potential of spillover of bat-borne coronaviruses, as evidenced by the recent spillover of swine acute diarrhoea syndrome coronavirus (SADS-CoV) to pigs. Read More

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http://dx.doi.org/10.1038/s41579-018-0118-9DOI Listing
December 2018

Prisoners of war - host adaptation and its constraints on virus evolution.

Nat Rev Microbiol 2018 Dec 5. Epub 2018 Dec 5.

Department of Zoology, University of Oxford, Oxford, UK.

Recent discoveries of contemporary genotypes of hepatitis B virus and parvovirus B19 in ancient human remains demonstrate that little genetic change has occurred in these viruses over 4,500-6,000 years. Endogenous viral elements in host genomes provide separate evidence that viruses similar to many major contemporary groups circulated 100 million years ago or earlier. In this Opinion article, we argue that the extraordinary conservation of virus genome sequences is best explained by a niche-filling model in which fitness optimization is rapidly achieved in their specific hosts. Read More

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http://dx.doi.org/10.1038/s41579-018-0120-2DOI Listing
December 2018
1 Read

Sequencing in the time of Ebola.

Nat Rev Microbiol 2019 Jan;17(1)

Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.

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http://dx.doi.org/10.1038/s41579-018-0130-0DOI Listing
January 2019

Viral RNA structure-based strategies to manipulate translation.

Nat Rev Microbiol 2018 Dec 4. Epub 2018 Dec 4.

Department of Biochemistry and Molecular Genetics, University of Colorado Denver School of Medicine, Aurora, CO, USA.

Viruses must co-opt the cellular translation machinery to produce progeny virions. Eukaryotic viruses have evolved a variety of ways to manipulate the cellular translation apparatus, in many cases using elegant RNA-centred strategies. Viral RNAs can alter or control every phase of protein synthesis and have diverse targets, mechanisms and structures. Read More

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http://dx.doi.org/10.1038/s41579-018-0117-xDOI Listing
December 2018

Changing your sugar coat.

Authors:
Andrea Du Toit

Nat Rev Microbiol 2018 Nov 28. Epub 2018 Nov 28.

Nature Reviews Microbiology, .

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http://dx.doi.org/10.1038/s41579-018-0131-zDOI Listing
November 2018

Host and viral determinants of influenza A virus species specificity.

Nat Rev Microbiol 2018 Nov 28. Epub 2018 Nov 28.

Department of Medicine, Imperial College London, London, UK.

Influenza A viruses cause pandemics when they cross between species and an antigenically novel virus acquires the ability to infect and transmit between these new hosts. The timing of pandemics is currently unpredictable but depends on ecological and virological factors. The host range of an influenza A virus is determined by species-specific interactions between virus and host cell factors. Read More

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http://dx.doi.org/10.1038/s41579-018-0115-zDOI Listing
November 2018

Reduce your speed.

Authors:
Ashley York

Nat Rev Microbiol 2019 Jan;17(1)

Nature Reviews Microbiology, .

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http://dx.doi.org/10.1038/s41579-018-0127-8DOI Listing
January 2019

A villain turns good.

Authors:
Ashley York

Nat Rev Microbiol 2019 Jan;17(1):2-3

Nature Reviews Microbiology, .

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http://dx.doi.org/10.1038/s41579-018-0126-9DOI Listing
January 2019

The cost of antimicrobial resistance.

Authors:
Ursula Hofer

Nat Rev Microbiol 2019 Jan;17(1)

Nature Reviews Microbiology, .

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http://dx.doi.org/10.1038/s41579-018-0125-xDOI Listing
January 2019

Author Correction: Biofilm-associated infection by enterococci.

Nat Rev Microbiol 2018 Nov 20. Epub 2018 Nov 20.

Singapore Centre for Environmental Life Sciences Engineering, Nanyang Technological University, Singapore, Singapore.

In the section on initial attachment and in Figure 1 it was erroneously indicated that enterococcal surface protein (Esp) binds collagen and fibrinogen. The text and figure were changed to remove this binding interaction both online and in the pdf. The authors apologize for any confusion caused. Read More

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http://dx.doi.org/10.1038/s41579-018-0128-7DOI Listing
November 2018

Growth capacity and cell size.

Authors:
Andrea Du Toit

Nat Rev Microbiol 2019 Jan;17(1)

Nature Reviews Microbiology, .

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http://dx.doi.org/10.1038/s41579-018-0124-yDOI Listing
January 2019

Decomposition responses to climate.

Authors:
Andrea Du Toit

Nat Rev Microbiol 2019 Jan;17(1)

Nature Reviews Microbiology, .

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http://dx.doi.org/10.1038/s41579-018-0123-zDOI Listing
January 2019

Let's get moving.

Authors:
Andrea Du Toit

Nat Rev Microbiol 2019 Jan;17(1)

Nature Reviews Microbiology, .

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http://dx.doi.org/10.1038/s41579-018-0122-0DOI Listing
January 2019

Well-timed toxin export.

Authors:
Andrea Du Toit

Nat Rev Microbiol 2019 Jan;17(1):2-3

Nature Reviews Microbiology, .

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http://dx.doi.org/10.1038/s41579-018-0119-8DOI Listing
January 2019

Mycobiome diversity: high-throughput sequencing and identification of fungi.

Nat Rev Microbiol 2018 Nov 15. Epub 2018 Nov 15.

Natural History Museum of Tartu University, Tartu, Estonia.

Fungi are major ecological players in both terrestrial and aquatic environments by cycling organic matter and channelling nutrients across trophic levels. High-throughput sequencing (HTS) studies of fungal communities are redrawing the map of the fungal kingdom by hinting at its enormous - and largely uncharted - taxonomic and functional diversity. However, HTS approaches come with a range of pitfalls and potential biases, cautioning against unwary application and interpretation of HTS technologies and results. Read More

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http://www.nature.com/articles/s41579-018-0116-y
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http://dx.doi.org/10.1038/s41579-018-0116-yDOI Listing
November 2018
29 Reads

Diverse light responses of cyanobacteria mediated by phytochrome superfamily photoreceptors.

Nat Rev Microbiol 2019 Jan;17(1):37-50

Department of Biology, Indiana University, Bloomington, IN, USA.

Cyanobacteria are an evolutionarily and ecologically important group of prokaryotes. They exist in diverse habitats, ranging from hot springs and deserts to glaciers and the open ocean. The range of environments that they inhabit can be attributed in part to their ability to sense and respond to changing environmental conditions. Read More

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http://www.nature.com/articles/s41579-018-0110-4
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http://dx.doi.org/10.1038/s41579-018-0110-4DOI Listing
January 2019
5 Reads

Types and origins of bacterial membrane vesicles.

Nat Rev Microbiol 2019 Jan;17(1):13-24

Department of Plant and Microbial Biology, University of Zurich, Zurich, Switzerland.

Most bacteria release membrane vesicles (MVs) that contain specific cargo molecules and have diverse functions, including the transport of virulence factors, DNA transfer, interception of bacteriophages, antibiotics and eukaryotic host defence factors, cell detoxification and bacterial communication. MVs not only are abundant in nature but also show great promise for applications in biomedicine and nanotechnology. MVs were first discovered to originate from controlled blebbing of the outer membrane of Gram-negative bacteria and are therefore often called outer-membrane vesicles (OMVs). Read More

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http://www.nature.com/articles/s41579-018-0112-2
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http://dx.doi.org/10.1038/s41579-018-0112-2DOI Listing
January 2019
11 Reads

Light sensing and responses in fungi.

Nat Rev Microbiol 2019 Jan;17(1):25-36

Karlsruhe Institute of Technology (KIT) - South Campus, Institute for Applied Biosciences, Department of Microbiology, Karlsruhe, Germany.

Light controls important physiological and morphological responses in fungi. Fungi can sense near-ultraviolet, blue, green, red and far-red light using up to 11 photoreceptors and signalling cascades to control a large proportion of the genome and thereby adapt to environmental conditions. The blue-light photoreceptor functions directly as a transcriptional regulator in the nucleus, whereas the red-light-sensing and far-red-light-sensing phytochrome induces a signalling pathway to transduce the signal from the cytoplasm to the nucleus. Read More

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http://www.nature.com/articles/s41579-018-0109-x
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http://dx.doi.org/10.1038/s41579-018-0109-xDOI Listing
January 2019
7 Reads

EV-D68 steps up its neurotropism.

Authors:
Ursula Hofer

Nat Rev Microbiol 2018 Dec;16(12):718-719

Nature Reviews Microbiology, .

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http://dx.doi.org/10.1038/s41579-018-0114-0DOI Listing
December 2018

Sharing with your community.

Authors:
Andrea Du Toit

Nat Rev Microbiol 2018 Dec;16(12):718-719

Nature Reviews Microbiology, .

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http://dx.doi.org/10.1038/s41579-018-0113-1DOI Listing
December 2018

Biofilm-associated infection by enterococci.

Nat Rev Microbiol 2018 Oct 18. Epub 2018 Oct 18.

Singapore Centre for Environmental Life Sciences Engineering, Nanyang Technological University, Singapore, Singapore.

Enterococci are ubiquitous members of the human gut microbiota and frequent causes of biofilm-associated opportunistic infections. Enterococci cause 25% of all catheter-associated urinary tract infections, are frequently isolated in wounds and are increasingly found in infective endocarditis, and all of these infections are associated with biofilms. Enterococcal biofilms are intrinsically tolerant to antimicrobials and thus are a serious impediment for treating infections. Read More

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http://www.nature.com/articles/s41579-018-0107-z
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http://dx.doi.org/10.1038/s41579-018-0107-zDOI Listing
October 2018
16 Reads

Developmental roadmap for antimicrobial susceptibility testing systems.

Nat Rev Microbiol 2019 Jan;17(1):51-62

bioMérieux, Data Analytics Unit, 100 Rodolphe Street, Durham, NC, USA.

Antimicrobial susceptibility testing (AST) technologies help to accelerate the initiation of targeted antimicrobial therapy for patients with infections and could potentially extend the lifespan of current narrow-spectrum antimicrobials. Although conceptually new and rapid AST technologies have been described, including new phenotyping methods, digital imaging and genomic approaches, there is no single major, or broadly accepted, technological breakthrough that leads the field of rapid AST platform development. This might be owing to several barriers that prevent the timely development and implementation of novel and rapid AST platforms in health-care settings. Read More

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http://www.nature.com/articles/s41579-018-0098-9
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http://dx.doi.org/10.1038/s41579-018-0098-9DOI Listing
January 2019
14 Reads

Silencing Staphylococcus aureus with probiotics.

Authors:
Ashley York

Nat Rev Microbiol 2018 Dec;16(12):715

Nature Reviews Microbiology, .

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http://www.nature.com/articles/s41579-018-0111-3
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http://dx.doi.org/10.1038/s41579-018-0111-3DOI Listing
December 2018
8 Reads

Time to split.

Authors:
Andrea Du Toit

Nat Rev Microbiol 2018 Dec;16(12):716-717

Nature Reviews Microbiology, .

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http://dx.doi.org/10.1038/s41579-018-0108-yDOI Listing
December 2018
6 Reads

Coming together during viral assembly.

Nat Rev Microbiol 2018 Dec;16(12):721

Clarendon Laboratory, Department of Physics, University of Oxford, Oxford, UK.

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http://www.nature.com/articles/s41579-018-0102-4
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December 2018
7 Reads

An expanding fungal tree of life.

Authors:
Ashley York

Nat Rev Microbiol 2018 Dec;16(12):719

Nature Reviews Microbiology, .

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http://www.nature.com/articles/s41579-018-0106-0
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December 2018
6 Reads

A useful by-product.

Authors:
Ashley York

Nat Rev Microbiol 2018 Dec;16(12):719

Nature Reviews Microbiology, .

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http://www.nature.com/articles/s41579-018-0105-1
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December 2018
5 Reads

Plant probiotic supresses bacterial wilt.

Authors:
Ashley York

Nat Rev Microbiol 2018 Dec;16(12):719

Nature Reviews Microbiology, .

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http://www.nature.com/articles/s41579-018-0104-2
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December 2018
10 Reads

The oral microbiota: dynamic communities and host interactions.

Nat Rev Microbiol 2018 Dec;16(12):745-759

Department of Microbiology, Penn Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.

The dynamic and polymicrobial oral microbiome is a direct precursor of diseases such as dental caries and periodontitis, two of the most prevalent microbially induced disorders worldwide. Distinct microenvironments at oral barriers harbour unique microbial communities, which are regulated through sophisticated signalling systems and by host and environmental factors. The collective function of microbial communities is a major driver of homeostasis or dysbiosis and ultimately health or disease. Read More

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http://www.nature.com/articles/s41579-018-0089-x
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278837PMC
December 2018
17 Reads

Author Correction: Microbial niches in marine oxygen minimum zones.

Nat Rev Microbiol 2018 Dec;16(12):774

School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, USA.

In Figure  3, 'Candidatus Scalindua' and Thaumarchaeota were erroneously shown to produce nitrous oxide (NO). As neither group directly produces NO, the arrows and products have been removed both online and in the pdf. The authors apologize for any confusion caused. Read More

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http://www.nature.com/articles/s41579-018-0103-3
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http://dx.doi.org/10.1038/s41579-018-0103-3DOI Listing
December 2018
8 Reads

Shaping human evolution.

Authors:
Andrea Du Toit

Nat Rev Microbiol 2018 Dec;16(12):717

Nature Reviews Microbiology, .

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http://www.nature.com/articles/s41579-018-0099-8
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December 2018
5 Reads

Diet and the mammary gland microbiome.

Authors:
Andrea Du Toit

Nat Rev Microbiol 2018 Dec;16(12):717

Nature Reviews Microbiology, .

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http://www.nature.com/articles/s41579-018-0101-5
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http://dx.doi.org/10.1038/s41579-018-0101-5DOI Listing
December 2018
12 Reads

Profilin(g) Asgard archaea.

Authors:
Andrea Du Toit

Nat Rev Microbiol 2018 Dec;16(12):717

Nature Reviews Microbiology, .

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http://dx.doi.org/10.1038/s41579-018-0100-6DOI Listing
December 2018

The majority is uncultured.

Authors:
Ursula Hofer

Nat Rev Microbiol 2018 Dec;16(12):716-717

Nature Reviews Microbiology, .

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http://www.nature.com/articles/s41579-018-0097-x
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December 2018
2 Reads

Making matters worse.

Authors:
Ashley York

Nat Rev Microbiol 2018 Nov;16(11):659

Nature Reviews Microbiology, .

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http://dx.doi.org/10.1038/s41579-018-0094-0DOI Listing
November 2018

Exploiting peroxisomes.

Authors:
Ashley York

Nat Rev Microbiol 2018 Nov;16(11):659

Nature Reviews Microbiology, .

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http://dx.doi.org/10.1038/s41579-018-0095-zDOI Listing
November 2018

Stronger together.

Authors:
Ashley York

Nat Rev Microbiol 2018 Nov;16(11):659

Nature Reviews Microbiology, .

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http://www.nature.com/articles/s41579-018-0096-y
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November 2018
3 Reads

Surf's up!

Authors:
Ashley York

Nat Rev Microbiol 2018 Nov;16(11):658-659

Nature Reviews Microbiology, .

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http://dx.doi.org/10.1038/s41579-018-0093-1DOI Listing
November 2018
3 Reads

Folding unstable proteins.

Authors:
Andrea Du Toit

Nat Rev Microbiol 2018 Nov;16(11):658

Nature Reviews Microbiology, .

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http://www.nature.com/articles/s41579-018-0092-2
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November 2018
5 Reads