Search Our Scientific Publications & Authors

Pediatr Pulmonol 2019 Feb 18. Epub 2019 Feb 18.

Neonatal Intensive Care Unit, Cruces University Hospital, Barakaldo, Bizkaia, Spain.

Background: Nasal continuous-positive airway pressure (nCPAP) with the INSURE (INtubation-SURfactant-Extubation) or LISA (Less-Invasive Surfactant Administration) procedures are increasingly being chosen as the initial treatment for neonates with surfactant deficiency. Our objective was to compare the effects on cerebral oxygenation of different methods for surfactant administration: INSURE and LISA, using a nasogastric tube (NT) or a LISAcath® catheter, in spontaneously breathing SF-deficient newborn piglets.

Methods: Eighteen newborn piglets with SF-deficient lung injury produced by repetitive bronchoalveolar lavages were randomly assigned to INSURE, LISA-NT, or LISAcath® groups. Read More

Zhen Ci Yan Jiu 2019 Jan;44(1):43-6

Intensive Care Unit, Changxing County Hospital of Traditional Chinese Medicine, Huzhou 313000, Zhejiang Province, China.

Objective: To observe the clinical therapeutic effect of acupuncture of Huatuo Jiaji (EX-B2) in the treatment of gastrointestinal dysfunction in sepsis patients, aiming at providing new clinical approach and evidence for improving septic gastrointestinal activity.

Methods: A total of 40 patients with septic gastrointestinal dysfunction who met our inclusive criteria were randomly divided into control group and treatment group (＝20 cases in each). Patients in the control group received routine treatment of nasogastric mosapride citrate (5 mg/time, three times a day) and tifidobacterium triple viable capsules (420 mg, twice a day), intravenous infusion of omeprazole (40 mg, twice a day), rational dose of antibiotics, maintenance treatment of functions of the heart, lung, brain, kidney and other important organs and water electrolyte balance, as well as symptomatic treatment. Read More

J Vasc Interv Radiol 2019 Feb 14. Epub 2019 Feb 14.

Department of Interventional and Diagnostic Imaging, Cancer Center Antoine Lacassagne, Nice 06189, France. Electronic address:

Percutaneous radiologic gastrostomy (PRG) requires preliminary gastric inflation through a nasogastric tube (NGT) to safely perform gastric puncture. However, in case of pharyngeal or esophageal obstruction, NGT placement may be impossible even with a hydrophilic angiography catheter and wire. This brief report describes percutaneous computed tomography (CT)-guided gastrostomy with a 2-stick approach without nasogastric insufflation in 13 patients. Read More

J Pediatr Surg 2019 Jan 22. Epub 2019 Jan 22.

Pediatric Surgery department, Ain Shams University, Cairo, Egypt.

Background: Difficult caustic esophageal strictures may need a more sophisticated dilatation technique before referring for esophageal replacement surgery.

Patients & Method: Retrospective review of caustic esophageal strictures managed at our center between January 2010 and June 2018 was done. Twenty two patients labeled as undilatable strictures were enrolled. Read More

Acta Otorrinolaringol Esp 2019 Feb 14. Epub 2019 Feb 14.

Departamento de Otorrinolaringología, Centro Clínico de Cabeza y Cuello, Ciudad de Guatemala, Guatemala.

Background And Objective: to describe the results of the treatment of invasive fungal sinusitis with nasal endoscopic surgery in an immunocompromised paediatric oncological population.

Methods: retrospective study of all patients diagnosed with invasive fungal sinusitis operated in the National Paediatric Oncology Unit between 2012 and 2016. Data taken from their medical history included: epidemiological characteristics, oncological diagnosis, haematological data, symptoms, tomographic studies, surgical interventions, results of pathology and cultures, medications received, complications, evolution and survival. Read More

Clin Perinatol 2019 Mar 13;46(1):77-88. Epub 2018 Dec 13.

Department of Pediatrics, NorthShore University HealthSystem, Evanston Hospital, 2650 Ridge Avenue, Evanston, IL 60201, USA; Pritzker School of Medicine, University of Chicago, Chicago, IL, USA.

Oropharyngeal administration of mother's own milk-placing drops of milk directly onto the neonate's oral mucosa-may serve to (ex utero) mimic the protective effects of amniotic fluid for the extremely low birth weight infant; providing protection against necrotizing enterocolitis. This article presents current evidence to support biological plausibility for the use of OroPharyngeal Therapy with Mother's Own Milk (OPT-MOM) as an immunomodulatory therapy; an adjunct to enteral feeds of mother's milk administered via a nasogastric or orogastric tube. Current methods and techniques are reviewed, published evidence to guide clinical practice will be presented, and controversies in practice will be addressed. Read More

J Crit Care Med (Targu Mures) 2019 Jan 4;5(1):19-27. Epub 2019 Feb 4.

University of Szeged, Department of Anaesthesiology and Intensive Therapy, Szeged, Hungary.

Lung protective mechanical ventilation (LPV) even in patients with healthy lungs is associated with a lower incidence of postoperative pulmonary complications (PPC). The pathophysiology of ventilator-induced lung injury and the risk factors of PPCs have been widely identified, and a perioperative lung protective concept has been elaborated. Despite the well-known advantages, results of recent studies indicated that intraoperative LPV is still not widely implemented in current anaesthesia practice. Read More

Medicine (Baltimore) 2019 Feb;98(7):e14502

Department of Family Medicine.

The aim of this study was to evaluate the impact of home health care (HHC) for disabled patients.We conducted a nationwide population-based retrospective cohort study. A total of 5838 disabled patients with HHC were identified to match by propensity score with 15,829 disabled patients without HHC receiving tube or catheter care (tracheostomy tube, nasogastric tube, urinary catheter, cystostomy tube, nephrostomy tube) or stage 3 or 4 pressure sore care from the Taiwanese National Health Insurance Research Database between 2005 and 2009. Read More

Medicine (Baltimore) 2019 Feb;98(7):e14468

School of Chinese Medicine, China Medical University.

Reducing the need for advanced nursing care and medical expenses is an essential concern of dementia care. We investigated the impact of traditional Chinese medicine (TCM) on advanced nursing care and medical costs.We used Longitudinal Health Insurance Database to implement a cohort study of patients with dementia between 1997 and 2012 in Taiwan. Read More

Am Surg 2019 Jan;85(1):76-81

The aim was to prospectively document the impact of early late appendectomy on intestinal function in pediatric perforated appendicitis. After Institutional Review Board approval, between September 2016 and August 2017, complete data were prospectively collected for children undergoing planned appendectomy for perforated appendicitis. One hundred children with pathologist-confirmed transmural perforations were included. Read More

BMC Health Serv Res 2019 Feb 13;19(1):119. Epub 2019 Feb 13.

Department of Midwifery, School of Nurising and Midwifery, University of Health and Allied Sciences, Ho, Ghana.

Background: Data on nurses' adherence to standard protocol on nasogastric (NG) tube feeding remain scanty in Ghana even though patients in critical medical conditions are routinely managed using this procedure. This study explored self-rated adherence to standard protocols on NG tube feeding among professional and auxiliary nurses and the perceived barriers impeding compliance to these standard protocols.

Methods: This is a descriptive analytical cross-sectional study among professional (n = 89) and auxiliary (n = 24) nurses in a major referral hospital in one of the ten administrative regions in Ghana. Read More

Int J Pediatr Otorhinolaryngol 2019 Feb 5;120:40-43. Epub 2019 Feb 5.

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States.

Objectives: To study the incidence, sequelae, follow up, and recovery rate of vocal fold motion impairment (VFMI) after complex aortic arch reconstruction in neonates.

Study Design: Retrospective case control study.

Methods: We retrospectively evaluated 105 neonates who underwent complex aortic arch reconstruction from 2014 to 2016. Read More

J Nurs Res 2019 Feb 8. Epub 2019 Feb 8.

Contributed equally.

Background: Evidence-based studies propose that the aspirate pH test may be easily and reliably conducted to verify the proper placement of nasogastric tubes (NGTs). Nurses rarely implement this procedure because of the lack of related knowledge.

Purpose: The purpose of this study was to explore the feasibility of implementing a revised standard care procedure to enhance nurses' ability to verify placement of the NGT. Read More

Int J Nurs Stud 2019 Jan 14;92:73-78. Epub 2019 Jan 14.

Nursing Division, Singapore General Hospital, Singapore.

Background: Distance from the tip of the nose to earlobe to xiphisternum is commonly used to determine the length of nasogastric tube to be inserted. However, it is not evidence-based and frequently leads to improper positioning.

Objectives: This study evaluated four formulae and the distance from the tip of the nose to earlobe to xiphisternum in estimating the internal length of nasogastric tube required for optimal positioning. Read More

JAMA Neurol 2019 Feb 11. Epub 2019 Feb 11.

Department of Neurology, Kantonsspital St Gallen, St Gallen, Switzerland.

Importance: Predicting the duration of poststroke dysphagia is important to guide therapeutic decisions. Guidelines recommend nasogastric tube (NGT) feeding if swallowing impairment persists for 7 days or longer and percutaneous endoscopic gastrostomy (PEG) placement if dysphagia does not recover within 30 days, but, to our knowledge, a systematic prediction method does not exist.

Objective: To develop and validate a prognostic model predicting swallowing recovery and the need for enteral tube feeding. Read More

Haematologica 2019 Feb 7. Epub 2019 Feb 7.

Department of Hematology, Saint Antoine Hospital, Paris, France.

Fecal microbiota transplantation is an effective treatment in recurrent Clostridium difficile infection. Promising results to eradicate multidrug-resistant bacteria have also been reported with this procedure, but there are safety concerns in immunocompromised patients. We report results in 10 adult patients colonized with multidrug-resistant bacteria, undergoing fecal microbiota transplantation before (n=4) or after (n=6) allogeneic hematopoietic stem cell transplantation for hematologic malignancies. Read More

Curr Opin Crit Care 2019 Feb 5. Epub 2019 Feb 5.

Purpose Of Review: To review recent literature on the management of patients with severe acute pancreatitis (SAP) admitted to an ICU.

Recent Findings: SAP is a devastating disease associated with a high morbidity and mortality. Recent evidence advocates adequate risk assessment and severity prediction (including intra-abdominal pressure monitoring), tailored fluid administration favoring balanced crystalloids, withholding prophylactic antibiotic therapy, and early detection and treatment of extra-pancreatic and fungal infections. Read More

Pharmacology 2019 Feb 6;103(5-6):246-249. Epub 2019 Feb 6.

Clinical Pharmacology Unit, Department of Anaesthesia and Intensive Care, International Clinical Research Center, St. Anne's University Hospital Brno, Brno, Czech

Background/aims: Administration of tablets via feeding tube (FT) is often associated with significant drug losses, as was confirmed by weighing. The aim of this study was to measure the proportion of active substance losses (ASLs) in an in vitro model.

Methods: A film-coated tablet (FilmCT) containing clopidogrel (Trombex®) and a tablet with enteric coating (EntericCT) containing pantoprazole (Controloc®) were crushed in a mortar and transferred by method A (tablet powder was transferred into the beaker, poured into the syringe and water added) and method B (water was added into the mortar, suspension drawn into the syringe) and administered via FT in an in vitro model. Read More

Dev Med Child Neurol 2019 Feb 5. Epub 2019 Feb 5.

Neuropsychiatry and Neurorehabilitation Unit, Scientific Institute IRCCS Eugenio Medea, Bosisio Parini, Lecco, Italy.

Aim: To assess the predictive validity of the Functional Evaluation of Eating Difficulties Scale (FEEDS) on long-term eating developmental outcomes in infants with neurodevelopmental disorders.

Method: In total, 144 infants (69 females, 75 males) aged 0 to 12 months (mean [SD] 5.34mo [3. Read More

Zhonghua Wei Chang Wai Ke Za Zhi 2019 Jan;22(1):79-84

Department of Pathology, 920 Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army, Kunming 650032, China.Email:

Objective: To establish a modified endoscopic Freka Trelumina placement (mEFTP) for modifying or substituting the traditional endoscopic Freka Trelumina placement (EFTP) and to explore the safety and feasibility of mEFTP in patients requiring enteral nutrition and gastrointestinal decompression in general surgery.

Methods: A retrospective cohort study was conducted to analyze the clinical data of patients undergoing EFTP or mEFTP at General Surgery Department of 920 Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army from January 2016 to January 2018.

Inclusion Criteria: the function of lower digestive tract was normal; patients who could not eat through mouth or nasogastric tube needed to have enteral nutrition and gastrointestinal decompression; the retention time of Freka Trelumina (FT) was not expected to exceed 2 months. Read More

Turk Arch Otorhinolaryngol 2018 Dec 25;56(4):217-220. Epub 2018 Dec 25.

Department of Otorhinolaryngology, Tepecik Training and Research Hospital, İzmir, Turkey.

Objective: There is still no consensus on the effect of early oral feeding and nasogastric tube feeding on the development of pharyngocutaneous fistula (PCF) after total laryngectomy. The aim of the present study was to compare the effects of early oral feeding and nasogastric tube (NGT) feeding after total laryngectomy on the incidence of PCF.

Methods: A total of 59 male and three female patients with a mean age of 61. Read More

J Surg Res 2019 Apr 14;236:119-123. Epub 2018 Dec 14.

Division of Pediatric Surgery, Texas Children's Hospital/Baylor College of Medicine, Houston, Texas. Electronic address:

Background: In patients requiring gastrostomies, ventriculoperitoneal (VP) shunts are a frequently encountered comorbidity. The objective of this study is to evaluate the postoperative management of children with VP shunts that undergo laparoscopic gastrostomy placement and determine their incidence of complications.

Materials And Methods: Children 18 y old or younger who underwent laparoscopic gastrostomy placement at a freestanding academic children's hospital between January 2014 and October 2016 were reviewed. Read More

Saudi J Anaesth 2019 Jan-Mar;13(1):23-27

Department of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, Columbus, Ohio, USA.

Background: Naso/Orogastric tube (NOGT) misplacement can lead to significant complications. Therefore, the assessment of tube position is essential to ensure patient safety. Although radiography is considered the gold standard for determining NOGT location, new methods may be helpful in reducing repetitive radiation exposure, especially for neonates. Read More

Int J Eat Disord 2019 Jan 24. Epub 2019 Jan 24.

Division of Child and Family Mental Health and Developmental Neuroscience, Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, North Carolina.

Objective: This opinion piece offers some considerations, both medical and psychological, for the use of nasogastric tube (NGT) feedings in the treatment of avoidant restrictive food intake disorder (ARFID) in children and adolescents.

Method: Although there is empirical support for the use of NGT feedings in the treatment of anorexia nervosa, this evidence base does not exist for the treatment of ARFID. As such, there is need to delineate pragmatic considerations in the use of this procedure. Read More

GE Port J Gastroenterol 2018 Dec 7;26(1):59-63. Epub 2018 Mar 7.

Gastroenterology Department, Centro Hospitalar Universitário do Algarve, Faro, Portugal.

Gastrostomy site metastization is considered an uncommon complication of percutaneous endoscopic gastrostomy (PEG) placement in patients with head and neck tumours, but it is important to consider this possibility when evaluating gastrostomy-related symptoms. The authors present the case of a 40-year-old male with excessive alcohol consumption and active smoking, diagnosed with a stage IV oropharyngeal squamous cell carcinoma. The patient developed a paraneoplastic demyelinating motor polyneuropathy that, associated with tumour mass effect, caused dysphagia with need for nasogastric tube feeding. Read More

J Gastrointest Surg 2019 Jan 22. Epub 2019 Jan 22.

Center for Advanced Surgery, Baylor Scott and White Health, 3417 Gaston Avenue, Suite 1000 East, Dallas, TX, 75246, USA.

Perforations and leaks of the gastrointestinal tract are difficult to manage and are associated with high morbidity and mortality. Recently, endoscopic approaches have been applied with varying degrees of success. Most recently, the use of endoluminal vacuum therapy has been used with high success rates in decreasing both morbidity and mortality. Read More

Eur J Pediatr 2019 Jan 22. Epub 2019 Jan 22.

Department of Pediatrics, Albert Schweitzer Hospital (ASH), Dordrecht, The Netherlands.

Most premature infants are hospitalised until they no longer need monitoring of vital parameters and are independent of nasogastric tube feeding (NTF). Hospital admission time easily reaches a length of multiple months in extremely preterm infants, but also in late preterms, in whom drinking may be the only problem, hospital admission time can reach weeks. This is a very stressful time for both parents and child. Read More

Aust Crit Care 2019 Jan 19. Epub 2019 Jan 19.

Division of Critical Care, Christian Medical College, Vellore, India.

Background: Failure of Non-Invasive Ventilation (NIV) is associated with increased morbidity and mortality among critically ill patients. Although there is evidence of association between disease related factors and NIV failure, it is unclear whether factors related to NIV application contribute to NIV failure.

Objectives: To evaluate NIV failure rate and factors associated with NIV failure. Read More

Zhonghua Yi Xue Za Zhi 2018 Dec;98(48):3936-3940

Intensive Care Unit, Tongzhou People's Hospital, Nantong 226300, China.

To investigate the effects of nasogastric tube (NGT) and percutaneous endoscopic gastrostomy (PEG) tube feeding on the susceptibility of pulmonary infection in long-term coma patients with stroke or traumatic brain injury. A total of 295 candidates who were in long-term coma after stroke or traumatic brain injury but without pulmonary infection and eligible for PEG catheterization were screened prospectively between January 2014 and February 2018. The patients were divided into PEG group (86 patients) and NGT group (209 patients) according to the choice of next-of-kin. Read More

Heart Lung 2019 Jan 18. Epub 2019 Jan 18.

Childrens Hospital, Wayne State University, 3901 Beaubien Street, Detroit, MI, USA. Electronic address:

The purpose of this review was to (1) identify areas of agreement and disagreement in guidelines/recommendations to distinguish between gastric and pulmonary placement of nasogastric tube and (2) summarize factors that affect choices made by clinicians regarding which method(s) to use in specific situations. Systematic searches were conducted in the PubMed, Scopus, and CINAHL Plus databases using a combination of keywords and data-specific subject headings. Searches were limited to guidelines/recommendations from national level specialty groups and governmental sources published in the English language between January 1, 2015 and September 20, 2018. Read More

Emerg Med Int 2018 18;2018:2370426. Epub 2018 Dec 18.

Department of Emergency Medicine, Girne University Dr. Suat Günsel Hospital, Girne 99320, KKTC, Cyprus.

The objective of this study was to verify the nasogastric tube position with neck ultrasound and subxiphoid ultrasound, by giving air-water mixture and auscultation and to compare the effectiveness of these methods with chest radiography. This is a single-center, prospective, single-blind study. Patients who were admitted to our emergency department and had an indication of nasogastric tube placement were included. Read More

Korean J Gastroenterol 2018 Dec;72(6):308-312

Division of Gastroenterology, Department of Internal Medicine, Chungnam National University School of Medicine, Daejeon, Korea.

Percutaneous endoscopic gastrostomy (PEG) is widely used to provide nutritional support for patients with dysphagia and/or disturbed consciousness preventing oral ingestion, and PEG tube placement is a relatively safe and convenient non-surgical procedure performed under local anesthesia. However, the prevention of PEG-insertion-related complications is important. A 64-year-old man with recurrent pneumonia underwent tracheostomy and nasogastric tube placement for nutritional support and opted for PEG tube insertion for long-term nutrition. Read More

A A Pract 2019 Jan 10. Epub 2019 Jan 10.

From the Department of Anesthesiology, Kawasaki Municipal Hospital, Kanagawa, Japan.

Dental injury is one of the most common complications of tracheal intubation. Although teeth dislodged during tracheal intubation are usually found in the oral cavity, we encountered a case of a missing tooth found in the nasal cavity in an intubated patient. A 62-year-old man with 4 loose teeth in the upper jaw was scheduled for laparoscopic hernia repair. Read More

Emergencias 2018 Dic;30(6):419-423

Servicio de Aparato Digestivo, Hospital Universitari ParcTaulí. Institut d'Investigació i Innovació ParcTaulí, Barcelona, España. Departamento de Medicina. Universitat Autònoma de Barcelona, España.

Objectives: The American College of Gastroenterology's 2016 clinical guidelines for treating lower gastrointestinal (GI) tract bleeding recommends evaluating of nasogastric tube aspiration and the ratio of blood urea nitrogen (BUN) to creatinine to differentiate upper from lower GI bleeds. However, the evidence base to support recommending these 2 diagnostic variables is low. This study aimed to evaluate the diagnostic utility of nasogastric tube aspiration and the BUN-to-creatinine ratio for distinguishing between upper and lower GI bleeding. Read More

Dig Surg 2019 Jan 11:1-10. Epub 2019 Jan 11.

Department of Gynaecological Oncology, Metaxa Cancer Hospital, Piraeus, Greece.

Background: Postoperative ileus prolongs both hospital stay and patients' morbidity, having at the same time a great impact on health care costs. Coffee, a worldwide popular, cheap beverage might have an important effect on the motility of the postoperative bowel.

Methods: PubMed, Scopus, and Cochrane Central Register of Controlled Trials were systematically searched. Read More

J Appl Physiol (1985) 2019 Jan 10. Epub 2019 Jan 10.

National Centre for Sport and Exercise Medicine, Loughborough University, United Kingdom.

Knowledge of hydration status may contribute to hypohydration-induced exercise performance decrements, therefore, this study compared blinded and unblinded hypohydration on cycling performance. Fourteen trained, non-heat acclimated cyclists (age 25 ± 5 y; V̇O 63.3 ± 4. Read More

J Tissue Viability 2018 Dec 31. Epub 2018 Dec 31.

Institute of Clinical Research, Medanta the Medicity, Gurgaon, Haryana, 122001, India.

Background: Pressure ulcers (PU) usually occur over bony prominences in hospitalized patients. But they may occur due to medical devices referred also as Medical device related pressure ulcers (MDRPU). The United States National advisory panel (NPUAP) recognizes it as an important entity. Read More

Acta Neurochir Suppl 2019 ;125:51-55

Institute of Neurosurgery, Catholic University School of Medicine, Rome, Italy.

More than 100 years after the first description by Kanavel of a transoral-transpharyngeal approach to remove a bullet impacted between the atlas and the clivus [1], the transoral approach (TOA) still represents the 'gold standard' for surgical treatment of a variety of conditions resulting in anterior craniocervical compression and myelopathy [2, 3]. Nevertheless, some concerns-such as the need for a temporary tracheostomy and a postoperative nasogastric tube, and the increased risk of infection resulting from possible bacterial contamination and nasopharyngeal incompetence [4-6]-led to the introduction of the endoscopic endonasal approach (EEA) by Kassam et al. [7] in 2005. Read More

J Clin Med 2019 Jan 2;8(1). Epub 2019 Jan 2.

Department of Emergency Medicine, Asan Medical Center, College of Medicine, University of Ulsan, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea.

Risk assessment for upper gastrointestinal bleeding (UGIB) is important; however, current scoring systems are insufficient. We aimed to develop and validate a prediction model for rapidly determining the occurrence of hypotension in non-variceal UGIB patients with normotension (systolic blood pressure ≥90 mmHg) at emergency department presentation. In this prospective observational cohort study, consecutive non-variceal UGIB patients between January 2012 and April 2017 were enrolled. Read More

Acta Anaesthesiol Scand 2019 Jan 4. Epub 2019 Jan 4.

Department of Anesthesia and Critical Care Medicine, Cairo University, Cairo, Egypt.

Background: Diabetic patients are claimed to have high risk of delayed gastric emptying; however, the evidence concerning residual gastric volume in fasting diabetic patients is not consistent. The aim of this work is to evaluate residual gastric volume in fasting diabetic patients for elective surgery.

Methods: Fifty patients scheduled for elective surgery under general anaesthesia were included in the study. Read More

Obes Surg 2019 Jan 3. Epub 2019 Jan 3.

Division of Digestive and Transplant Surgery, Department of Surgery, University Hospital Geneva, 4 Rue Gabrielle-Perret-Gentil, 1211, Geneva, Switzerland.

Introduction: Leak tests using air or methylene blue (MB) for gastrojejunal anastomoses are often performed during gastric bypass surgeries to avoid leaks due to technical errors. Still, early leaks have been reported in the literature. Indocyanine green (ICG) fluorescence with laser excitement makes this dye easily visible even in small amounts, and, thus, may be an excellent agent for leak testing. Read More

Head Neck 2018 Dec 31. Epub 2018 Dec 31.

University of California at Davis, Department of Otolaryngology - Head and Neck Surgery, Sacramento, California.

This article is a part of the "Do you know your guidelines" series by the Education Committee of the American Head and Neck Society. The aim is to summarize the core principles outlined by the NCCN Clinical Practice Guidelines In Oncology (NCCN Guidelines ) on management of malnutrition in patients with head and neck cancer. We outline the current recommendations from the National Comprehensive Cancer Network (NCCN ) for the screening and management of malnutrition, including indications for nutritional supplementation and placement of a nasogastric or gastrostomy tube. Read More

Rev Infirm 2018 Dec;67(246):40-42

Service d'hématologie adulte, CHU Pontchaillou, 2, rue Henri-le-Guilloux, 35000 Rennes, France. Electronic address:

The use of a nasogastric tube can prevent certain complications in patients treated for malignant hematopathy. But this treatment is often experienced as a traumatic act by patients and sometimes even by caregivers. A Rennes hospital team shares with us the results of a retrospective study on the interest of the autonomous insertion of nasogastric tubes by hypnotic accompaniment. Read More

Zhonghua Wei Chang Wai Ke Za Zhi 2018 Dec;21(12):1387-1390

Department of General Surgery, Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital, Nanjing 210008, China.Email:

Objective: To investigate the risk factors of methicillin-resistant Staphylococcus aureus(MRSA) enterocolitis after gastrointestinal surgery.

Methods: Clinical and pathological data of 17 cases with MRSA enteritis after gastrointestinal surgery from March 2015 to March 2017 at Department of General Surgery of Affiliated Drum Tower Hospital were retrospectively analyzed.

Inclusion Criteria: (1) age of 18 to 80 years;(2) with history of gastrointestinal surgery; (3) diarrhea symptoms within 7 days after gastrointestinal surgery; (4) use of antibiotics before diarrhea; (5) fecal smear showing a large number of gram positive cocci; (6) fecal culture suggested the presence of MRSA; (7) application of antibiotic therapy against MRSA was effective. Read More

J Immunother Cancer 2018 Dec 27;6(1):156. Epub 2018 Dec 27.

Department of Medicine, Division of Immunology and Allergy, Lausanne University Hospital CHUV, rue du Bugnon 46, CH-1011, Lausanne, Switzerland.

Background: The prevalence of esophageal stenosis caused by immune checkpoint inhibitors in the context of induced immune mucositis and esophagitis is extremely rare.

Case Presentation: We report the case of a patient with stage IV pulmonary adenocarcinoma treated for 6 months with nivolumab who developed bilateral sterile conjunctivitis followed by oropharyngeal mucositis and esophagitis complicated by a severe esophageal stenosis. The laryngeal margin and hypopharyngeal mucosa appeared highly inflammatory with fibrinous deposits. Read More

Acta Microbiol Immunol Hung 2018 Dec 26:1-10. Epub 2018 Dec 26.

1 Department of Infectology, 1st Department of Internal Medicine, University of Pécs , Pécs, Hungary.

Dramatic changes in the epidemiology of Clostridium difficile infections have been reported from the western world in the past decade. The proportion of severe cases is significantly elevating and clinicians now have to contend with the problem of additional and more frequent episodes of recurrences including an upward trend in the mortality rate. This situation led us to investigate the possibility of the fecal microbiota transplantation (FMT). Read More

Hepatobiliary Pancreat Dis Int 2018 Dec 10. Epub 2018 Dec 10.

Department of Surgical Oncology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, UP 221005, India.

Background: Enhanced recovery after surgery (ERAS) protocol is a multimodal, multidisciplinary and evidence-based approach to reduce surgical stress and enhance recovery in the postoperative period. This study aimed to analyze the outcome of ERAS protocol in patients after pancreaticoduodenectomy (PD).

Methods: A total of 50 consecutive patients with pancreatic/periampullary cancer who underwent PD between January 2016 to August 2017 were included in the study. Read More

Open Med (Wars) 2018 6;13:556-561. Epub 2018 Dec 6.

Department of ultrasonography, China-Japan union Hospital, Jilin University, Changchun, Jilin 130033, China.

Objective: To investigate the effect of gastrointestinal function on the incidence of ventilator-associated pneumonia (VAP) in critically ill patients.

Methods: From August 2012 to June 2016, 160 critically ill patients in the ICU (Intensive Care Unit) of our hospital were selected as the research group; patients were divided equally into an observation group and a control group, 80 patients in each group, based on the random draw envelope principle. The control group was given a nasogastric tube for gastric feeding, the observation group was given a dual lumen gastrointestinal enteral device for gastric feeding; the two groups' enteral nutrition observation time was 7d; any changes in patient condition and prognosis were recorded. Read More

Dis Esophagus 2018 Dec 17. Epub 2018 Dec 17.

Peninsula Oesophago-gastric Centre, University Hospitals Plymouth NHS Trust, united Kingdom.

Delayed gastric emptying (DGE) is a common morbidity that affects 10%-50% of Ivor-Lewis gastroesophagectomy (ILGO) patients. DGE management is variable with no gold standard prevention or treatment. We conducted a study to assess the effectiveness of intraoperative pyloric botulinum toxin injection in preventing DGE. Read More