Search Our Scientific Publications & Authors

J Taibah Univ Med Sci 2022 May 13. Epub 2022 May 13.

Department of Infectious Diseases, Baharloo Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Objective: In the COVID-19 pandemic, the SARS-CoV-2 virus has infected millions of people worldwide. Mortality primarily results from the inflammation state and its complications. High-dose melatonin has been established as an anti-inflammatory agent. Read More

Am J Perinatol 2022 May 17. Epub 2022 May 17.

Division of Neonatology, Department of Pediatrics, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin.

Objective:  The aim of this study was to describe clinical outcomes of bridled nasogastric tube (NGT) program implementation for infants requiring assisted home feeding (AHF) to discharge from the neonatal intensive care unit (NICU).

Study Design:  This was a descriptive prospective analysis of a pilot cohort of infants after implementation of a bridled NGT AHF program to facilitate discharge from level III and IV NICUs from March 2019 to October 2020.

Results:  Of 29 attempts in infants, 22 infants were discharged with bridled NGTs over 18 months. Read More

Am J Clin Nutr 2022 May 16. Epub 2022 May 16.

University Centre for Nursing and Midwifery, Department of Public Health and Primary Care, Ghent University, Ghent, Belgium.

Background: Blind insertion of nasogastric tubes is performed for several reasons: Nutrition and medication administration, gastric aspiration/decompression, and other, diagnostic reasons. Accidental intraesophageal and intestinal placement is common, and increases the risk of serious complications. Therefore, accurate determination of the internal length of the nasogastric tube prior to placement is considered a prerequisite for achieving correct gastric positioning. Read More

Cureus 2022 May 12;14(5):e24946. Epub 2022 May 12.

Clinical Research, Clinical Research Strategies, Pittsburgh, USA.

Background Postoperative ileus (POI) is among the most common complications affecting patients who undergo major abdominal surgery. Because of the high volume of major surgery and the high incidence of postoperative ileus, failure to code for this complication may have a significant impact on hospital reimbursement and quality measures. Objectives This paper investigates the magnitude of the difference between the prevalence of POI as coded in administrative data versus the prevalence based upon a prospectively applied operational definition of POI in patients undergoing intestinal resection surgery. Read More

BMC Surg 2022 May 14;22(1):183. Epub 2022 May 14.

Department of Gastroenterology, The Second Hospital of Nanjing, Nanjing University of Chinese Medicine, 1 Zhongfu Road, Nanjing, Jiangsu, China.

Background: Previous studies reported that transnasal ileus tube was a new and useful method for rapid relief of small intestinal obstruction. However, no study reported the impacts of the transnasal ileus tube for Crohn's disease combined with intestinal obstruction. We aimed to describe the strategy to the small intestine obstruction caused by Crohn's disease on the basis of transnasal ileus tube insertion. Read More

Nutrients 2022 Apr 22;14(9). Epub 2022 Apr 22.

Department of Exercise and Health Promotion, College of Kinesiology and Health, Chinese Culture University, Taipei 11114, Taiwan.

Tube feeding (TF) is commonly used for patients with severe swallowing disturbance, and patients with chronic dysphagia are often provided with a long-term nasogastric tube (NGT). However, nationwide epidemiological data on long-term NGT placement are limited. The present study identified the prevalence and outcomes of patients with long-term NGT placement in Taiwan. Read More

Int J Environ Res Public Health 2022 Apr 29;19(9). Epub 2022 Apr 29.

Department of Oral Hygiene, College of Dental Medicine, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.

Home care patients have swallowing dysfunction and rely on an in-dwelling nasogastric tube (NGT) to complement oral food intake, supplement their diet, and maintain adequate nutritional status. This study explored the relationship between aspiration pneumonia (AP) and feeding care among home care patients with an in-dwelling NGT. This preliminary study employed a cross-sectional design. Read More

Surg Endosc 2022 May 13. Epub 2022 May 13.

Department of Surgery, Sinai Grace Hospital, Detroit Medical Center, Detroit, MI, USA.

Introduction: Minimally invasive or open Graham Patch repair remains the gold standard approach for management of perforated peptic ulcers (PPU). Herein, we report outcomes of laparoscopic technique and compare it with open approach at a community hospital.

Methods: Retrospective observational study conducted comparing laparoscopic modified Cellan-Jones repair (mCJR) versus the standard open repair of PPU. Read More

Surg Endosc 2022 May 12. Epub 2022 May 12.

Second Department of Surgery, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Tochigi, 321-0293, Japan.

Background: Laparoscopic surgery (LS) is reported to reduce postoperative complications and hospital stay compared with open surgery (OP). Because patient selection may have been biased in previous studies, propensity score matching (PSM) analysis was used in this study to test the benefits of LS compared with OP.

Methods: A total of 759 patients with stage I-III colorectal cancer undergoing curative surgery were retrospectively reviewed. Read More

J Med Eng Technol 2022 May 11:1-7. Epub 2022 May 11.

Department of Biomedical Physics and Technology, University of Dhaka, Dhaka, Bangladesh.

Nasogastric feeding is commonly used to deliver enteral feed in critically ill patients and several methods are used for assessing the gastric residual volume with limitations. A new approach for gastric emptying time measurement has been developed using Electric Impedance Method (EIM). The study aims to establish whether EIM is useful for measuring gastric emptying during nasogastric feeding compared with nasogastric suction. Read More

Eur J Clin Nutr 2022 May 9. Epub 2022 May 9.

Department of Radiation Oncology, Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine; Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangzhou, 510060, China.

Background: We aimed to identify which enteral feeding method was most beneficial for patients and compare clinical outcomes, quality of life, and complication rates by assessing patients who underwent prophylactic percutaneous endoscopic gastrostomy (pPEG) tube, reactive percutaneous endoscopic gastrostomy (rPEG) tube or reactive nasogastric tube (rNGT) insertion.

Methods: Patients with head and neck cancers (HNCs) were enrolled between April 1, 2013 and April 17, 2019 (n = 335; 296 males, 39 females). Data concerning patient characteristics and treatment modalities were extracted from the medical records. Read More

Case Rep Gastroenterol 2022 Jan-Apr;16(1):186-194. Epub 2022 Mar 28.

Department of Gastroenterology and Endoscopic Services, Western Health, Melbourne, Victoria, Australia.

Iatrogenic Stapfer type-1 duodenal perforations during endoscopic retrograde cholangiopancreatography (ERCP) typically necessitate surgical management and carry significant morbidity and mortality risk. Here, we present a case of a large duodenal perforation during ERCP managed endoscopically with an over-the-scope clip (OTSC) and describe the subsequent post-procedural management. An 80-year-old woman presented to the emergency department with acute cholangitis. Read More

Endocrinol Diabetes Nutr (Engl Ed) 2022 May 3. Epub 2022 May 3.

Servicio de Endocrinología y Nutrición, Hospital Universitari i Politècnic La Fe, Valencia, Spain.

Introduction: Although current recommendations suggest the use of specific formulas in enteral nutrition in people with diabetes, there is little evidence of their long-term effectiveness in glycemic control. The main objective of this study is to evaluate the long-term efficacy (24 weeks) of a specific high-protein hypercaloric enteral nutrition formula for people with diabetes in glycemic control and in their improvement in nutritional status.

Methodology: This was a multicenter, prospective, observational, real-life study of patients with long-term enteral nutrition prescription through gastrostomy or nasogastric tube who received a high protein hypercaloric formula specific for diabetes. Read More

Pediatrics 2022 May 6. Epub 2022 May 6.

Department of Surgery, Seattle Children's Hospital, University of Washington, Seattle, Washington.

Context: Despite frequency of gastrostomy placement procedures in children, there remains considerable variability in preoperative work-up and procedural technique of gastrostomy placement and a paucity of literature regarding patient-centric outcomes.

Objectives: This review summarizes existing literature and provides consensus-driven guidelines for patients throughout the enteral access decision-making process.

Data Sources: PubMed, Google Scholar, Medline, and Scopus. Read More

Arch Bronconeumol 2022 May 2. Epub 2022 May 2.

Servicio de Cirugía Torácica, Instituto Clínico Respiratorio, Hospital Clínic, Barcelona, Spain.

Front Nutr 2022 13;9:843945. Epub 2022 Apr 13.

Department of Neurology, Stroke Center & Clinical Trial and Research Center for Stroke, The First Hospital of Jilin University, Changchun, China.

Objectives: Post-stroke dysphagia may cause aspiration pneumonia, malnutrition, dehydration, and other complications. However, data on the effects of nutritional supplementation and its value after stroke are insufficient. We aimed to evaluate the effect of an individualized 1-week nutrition intervention program on swallowing function and nutritional status in stroke patients with oropharyngeal dysphagia. Read More

Cureus 2022 Mar 27;14(3):e23536. Epub 2022 Mar 27.

Gastroenterology, Parkview Medical Center, Pueblo, USA.

Parastomal hernia (PH) is an abnormal herniation of tissue or intra-abdominal organ through the fascial defect created at the ostomy site. It is a common complication of stoma creation and usually contains bowel, intra-abdominal fat, or omentum. Herniation of a fixed organ like the stomach is very rare and can lead to significant morbidity and mortality. Read More

J Am Med Dir Assoc 2022 Apr 27. Epub 2022 Apr 27.

Department of Medicine and Geriatrics, TWGHs Fung Yiu King Hospital, Hong Kong SAR, China.

Objectives: To compare survival and pneumonia risk among hospitalized patients with advanced dementia on nasogastric tube feeding (NGF) vs careful hand feeding (CHF) and to examine outcomes by feeding problem type.

Design: Retrospective cohort study.

Setting And Participants: Advanced dementia patients aged ≥60 years with indication for tube feeding admitted to 2 geriatric convalescent hospitals between January 1, 2015, and June 30, 2019. Read More

HPB (Oxford) 2022 Apr 5. Epub 2022 Apr 5.

Department of Digestive Surgical Oncology -Liver Transplantation Unit, CHU Besançon, France. Electronic address:

Background: Delayed return of gastrointestinal function (DGIF) after hepatectomy can involve increased morbidity and prolonged hospital stay. Yet, data on incidence and risks factors are lacking.

Methods: All consecutive patients who underwent hepatectomy between June 2018 and December 2020 were included. Read More

Eur J Intern Med 2022 Apr 22. Epub 2022 Apr 22.

IRCCS Azienda Ospedaliero Universitaria di Bologna, University Hospital Sant´Orsola-Malpighi- Respiratory and Critical Care Unit- Bologna, Italy; Alma Mater Studiorum, University of Bologna, Department of Clinical Integrated and Experimental Medicine (DIMES), Bologna, Italy. Electronic address:

Rationale And Objective: Various forms of Non-invasive respiratory support (NRS) have been used during COVID-19, to treat Hypoxemic Acute Respiratory Failure (HARF), but it has been suggested that the occurrence of strenuous inspiratory efforts may cause Self Induced Lung Injury(P-SILI). The aim of this investigation was to record esophageal pressure, when starting NRS application, so as to better understand the potential risk of the patients in terms of P-SILI and ventilator induced lung injury (VILI).

Methods And Measurements: 21 patients with early de-novo respiratory failure due to COVID-19, underwent three 30 min trials applied in random order: high-flow nasal cannula (HFNC), continuous positive airway pressure (CPAP), and non-invasive ventilation (NIV). Read More

Br J Clin Pharmacol 2022 Apr 25. Epub 2022 Apr 25.

Clinical Pharmacology & Quantitative Pharmacology (CPQP), Clinical Pharmacology and Safety Sciences, Research and Development, AstraZeneca, Cambridge, UK.

Aims: Acalabrutinib, a selective Bruton tyrosine kinase inhibitor is approved for the treatment of mantle cell lymphoma and chronic lymphocytic leukemia. Many critically ill patients are unable to swallow and need oral medications to be delivered via a nasogastric (NG) tube. Furthermore, critically ill patients are typically administered proton-pump inhibitors (PPIs) to prevent stress ulcers. Read More

HRB Open Res 2022 20;5. Epub 2022 Jan 20.

Irish Centre for Applied Patient Safety and Simulation, National University of Ireland, Galway, Galway, Co. Galway, H91 TK33, Ireland.

Newly graduated medical students often report that they lack the skills required to care for patients, and feel unprepared for clinical practice. However, little is known about when, and if, they acquire these skills in practice. The aim of this study was to assess self-reported level of entrustment in, and frequency of performance of, the seven Entrustable Professional Activities (EPAs) comprising the EPA framework for interns in Ireland. Read More

Front Cardiovasc Med 2022 30;9:826898. Epub 2022 Mar 30.

Department of Healthcare Administration and Medical Informatics, Kaohsiung Medical University, Kaohsiung, Taiwan.

Background: Few studies have compared the optimal duration and intensity of organized multidisciplinary neurological/rehabilitative care delivered in a regional/district hospital with the standard rehabilitative care delivered in the general neurology/rehabilitation ward of a medical center. This study measured functional outcomes and conducted cost-utility analysis of an organized multidisciplinary postacute care (PAC) project in secondary care compared with standard rehabilitative care delivered in tertiary care.

Methods: This prospective cohort study enrolled 1,476 patients who had a stroke between March 2014 and March 2018 and had a modified Rankin scale score of 2-4. Read More

Cureus 2022 Mar 14;14(3):e23154. Epub 2022 Mar 14.

Gastroenterology, NYU Langone, Woodhull Medical Center, New York, USA.

Advanced-stage pancreatic cancer can present as secondary gastric outlet obstruction (GOO), which is an extremely rare entity. Given the initial vague presentation of gastrointestinal symptoms, the diagnosis is often delayed, leading to high morbidity and mortality. We report the case of a 68-year-old male patient who presented with vomiting, epigastric pain, and weight loss. Read More

Case Rep Gastroenterol 2022 Jan-Apr;16(1):89-93. Epub 2022 Feb 24.

Division of Gastroenterohepatology, Department of Internal Medicine, Hasan Sadikin General Hospital-Faculty of Medicine University of Padjadjaran, Bandung, Indonesia.

Currently, gastroptosis is rarely reported, and the actual prevalence is unknown. Similarly, the possible predisposing factor and cause remain unclear. A 69-year-old had melena for 1 week, and other symptoms were left upper abdominal pain, nausea, and vomiting especially postprandially that was persistent for several months with no response to medication. Read More

Int Cancer Conf J 2022 Apr 2;11(2):124-128. Epub 2022 Feb 2.

Department of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, 1-1-5, Sendagi, Bunkyo-ku, Tokyo, 113-8603 Japan.

Superior mesenteric artery (SMA) syndrome is a rare disease, characterized by the narrowing of the third portion of the duodenum between the aorta and SMA. The cause of the stenosis is a decrease in retroperitoneal fat between the aorta and SMA. In this report, we present two cases of SMA syndrome that occurred during chemotherapy for lung cancer. Read More

Photodiagnosis Photodyn Ther 2022 Apr 6;38:102842. Epub 2022 Apr 6.

Department of Neonatal Surgery, Neonatal Center, Beijing Children's Hospital, National Center for Children's Health, Capital Medical University, Beijing 100045, China. Electronic address:

Background: A duodenal web refers to partial or complete obstruction of the duodenum due to a membranous web. When looking at the serosal side of the intestine during duodenal web excision, especially during laparoscopic surgery, determining the web origin might be challenging. This study aimed to determine the efficacy of intraduodenum indocyanine green injection and near-infrared light during laparoscopic surgery in enhancing the ability to identify duodenal web localization. Read More

Anaerobe 2022 Apr 5:102556. Epub 2022 Apr 5.

Department of Clinical Infectious Diseases, Aichi Medical University Graduate School of Medicine, Japan; Department of Infection Control and Prevention, Aichi Medical University Hospital, Japan; Department of Clinical Infectious Diseases, Aichi Medical University Hospital, Japan. Electronic address:

Objectives: Clostridioides difficile infection (CDI) often recurs. Approximately 25% of patients have recurrences after the initial treatment, and patients who have relapsed once are more likely to relapse. We aimed to identify the risk factors for initial CDI recurrence. Read More

Ethiop J Health Sci 2021 Nov;31(6):1257-1266

Neurosurgery Division - Department of Surgery, School of Medicine, AAU, Ethiopia.

Background: Ventriculostomy, a lifesaving and emergency procedure, is used to address raised intracranial pressure. In resource limited set-up like Tikur Annbessa Specialized Referral Hospital, properly designed closed system for ventriculostomy is not available; a device made with sterile pediatric nasogastric tube connected to urine bag is used.

Methods: Institutional based retrospective cross-sectional study conducted on 93 patients with ventriculostomy from January 1, 2009 to June 30, 2018. Read More

Front Surg 2022 22;9:807811. Epub 2022 Mar 22.

Zunyi Medical University, Zunyi, China.

Background: Colorectal cancer is a common malignant tumor appearing in the gastrointestinal tract. Surgical resection is recognized as the best means to improve patient survival. However, it is controversial whether early oral feeding (EOF) after elective colorectal resection demonstrates safety and efficacy in concerned clinical outcomes. Read More