193,667 results match your criteria Nasal Reconstruction


Sex-Specific Association between Prenatal Life Stress Exposure and Infant Pro-Inflammatory Cytokine Levels during Acute Respiratory Infection.

Brain Behav Immun 2018 Dec 11. Epub 2018 Dec 11.

Department of Medicine, Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, 37232-2650, USA.

Background: Prenatal life stress exposure is linked to dysregulated immune function and chronic inflammatory disease in offspring, but we know little about its effects on infant immune response during viral infection.

Method: To address this issue, we examined associations between prenatal life stress exposure and infant upper-airway inflammatory markers during acute respiratory infection (ARI) using data from a prospective, population-based birth-cohort study (N=180). Infant inflammation was measured as a continuous latent factor within a structural equation modeling framework using nasal wash concentrations of interleukin-1β, interleukin-6, and tumor necrosis factor-α. Read More

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December 2018

Repair of a Large Glabellar/Nasal Defect.

Dermatol Surg 2018 Dec 13. Epub 2018 Dec 13.

Mohs Micrographic and Skin Surgery PLLC, San Antonio, Texas.

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December 2018
1 Read

The Analysis of Computed Tomography of Paranasal Sinuses in Nasal Septal Deviation.

Authors:
Demet Yazici

J Craniofac Surg 2018 Dec 13. Epub 2018 Dec 13.

Adana Numune Training and Research Hospital, Ear Nose and Throat Department, Adana, Turkey.

Objectives: Anatomic variations of paranasal sinuses are frequent among population that should be analyzed and interpreted accurately. The purpose of this study is to analyze anatomical variants and their relationships of paranasal sinuses in patients with nasal septal deviation undergoing septoplasty.

Methods: A total number of 150 patients (74 males, 76 females) with nasal septal deviation undergoing septal surgery were included in this retrospective study. Read More

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December 2018

Septoplasty Under Local Anesthesia.

Authors:
Bojan Obradovic

J Craniofac Surg 2018 Dec 13. Epub 2018 Dec 13.

Dental/Medical Center of Maxillofacial Surgery "Aleja-Centar," Banja Luka, Bosnia and Herzegovina.

Septoplasty is usually performed under general anesthesia or local anesthesia with sedation. Nevertheless, septoplasty under pure local anesthesia is also feasible and it shows a great potential for fast-track surgery. This article presents a patient with nasal septal deviation where septoplasty was managed under local anesthesia at an outpatient clinic. Read More

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December 2018
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Perceptions of Attractive and Healthy-Looking Lips.

J Craniofac Surg 2018 Dec 13. Epub 2018 Dec 13.

Department of Plastic Surgery, Inha University School of Medicine, Incheon, Korea.

The aim of this study was to characterize Koreans' perceptions of attractive and healthy-looking lips.A survey was conducted among 258 women and 72 men who were asked to view illustrations of various examples of the 4 lip-related ratios (lip thickness-to-width ratio [LTW]; upper-to-lower vermillion ratio [ULR]; upper vermillion thickness-to-upper lip height ratio [VUL]; and lip-to-nose width ratio [LNW]) and to choose which they thought were attractive or healthy-looking.The LTW ratios most often identified as attractive were LTW-1/3 (lip thickness is 1/3 of lip width, 40. Read More

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December 2018

Hypogonadotropic hypogonadism and pituitary hypoplasia as recurrent features in Ulnar-Mammary syndrome.

Endocr Connect 2018 Dec;7(12):1432-1441

IRCCS Istituto Auxologico Italiano, Service of Medical Genetics, Milan, Italy.

Ulnar-mammary syndrome (UMS) is characterized by ulnar defects, and nipple or apocrine gland hypoplasia, caused by TBX3 haploinsufficiency. Signs of hypogonadism were repeatedly reported, but the mechanisms remain elusive. We aim to assess the origin of hypogonadism in two families with UMS. Read More

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December 2018

[Clinical features, diagnosis, treatment and prognosis of nasal Rosai-Dorfman' s disease: literature review].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(23):1843-1846

In our literature review, we searched the case reports of RosaiDorfman disease (RDD) in Chinese and English, and summarize clinical features, diagnosis and treatment of the disease. At present, it is believed that nasal RDD is a kind of benign cell hyperplastic disease, which mainly causes nasal obstruction, inflammation and nasal deformity, and is easy to misdiagnose. Optional treatments for this disease include medical treatment based on steroid therapy, which can alleviate and stabilize the disease; surgery can completely remove the lesions of some patients, or help some patients improve their symptoms. Read More

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December 2018

[Nasalleukoplakia:update on diagnosis and management].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(23):1836-1838

Nasal leukoplakia, defined as nasal mucosal grayish white lesion accompanied by adjacent mucosa thickening and hyperemia, is a kind of precancerous lesion. Since a case of nasal septum mucosal leukoplakia reported by Edley in 1955 and 62 cases of nasal leukoplakia reported by Liu Chun-Lin in 1964, few cases were reported. In this review, the pathogenesis, diagnosis and treatment of nasal mucosal leukoplakia are systematically summarized. Read More

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December 2018

[Nasal acinar cell carcinoma:a case report].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(23):1834-1835

Acinar cell carcinoma is a rare type of low-grade malignant tumor of the parotid gland epithelium. The progression of the disease is slow, and its tissue type and cell morphology are diverse. The diagnosis of tumor is difficult so that it is easy to cause missed diagnosis and misdiagnosis. Read More

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December 2018

[Metastases of cervical cancer to the nasal cavity and paranasal sinus with maxillofacial symptoms: a case report].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(23):1832-1833

A 41 year old female complained of left eyelid, cheek and face erythema, swelling with pain for 7 days. She was diagnosed with cervical squamous cell carcinoma, stage ⅢA a year ago. The anterior rhinoscopy examination showed that the dry scab adheres to the left nasal cavity, and a small amount of reddish mass were found, and the touch was brittle. Read More

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December 2018

[Effect of smoking on chronic rhinosinusitis complicated with lower respiratory tract disease].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(23):1826-1828

Department of Convalescence, People's Liberation Army Wuhan Sanatorium.

To study the effect of smoking on chronic rhinosinusitis with lower respiratory tract diseases and underlaying mechanism. The data of 54 patients diagnosed as CRS with lower respiratory disease (Group A) and 60 patients with CRS (Group B) from otolaryngology head and neck surgery in Wuhan Central Hospital and Renmin Hospital of Wuhan University from January 2014 to December 2017 were analyzed, retrospectively. According to the history of smoking, all patients were divided into smoking group (Group C) and non-smoking group (Group D). Read More

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December 2018

[Endoscopic keel placementto treat and prevent-bilateral vocal cord adhension].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(23):1821-1825

Department of Otorhinolaryngology Head and Neck Surgery, Eye Ear Nose Throat Hospital of Fudan University, Shanghai, 200031, China.

To investigate the effectiveness of endoscopic keel placement for the prevention and treatment of bilateral vocal cord adhesion. There are 47 cases with bilateral vocal cord lesions and 38 cases with laryngeal adhesion in this study. Bilateral vocal cord lesions were removed and laryngeal adhesion was cut and divided. Read More

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December 2018
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[The application of preoperative pulmonary function and FeNO test in patients with chronic rhinosinusitis].

Authors:
Y Liu A H Yan

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(23):1788-1791

Department of Otorhinolaryngology, the First Hospital of China Medical University, Shenyang, 110001, China.

To explore the application of lung function and exhaled nitric oxide in the evaluation of patients with chronic rhinosinusitis(CRS) with or without polyps who denied bronchial asthma history and planned to undergo endoscopic sinus surgery. Two hundred and thirty-two patients with CRS during April 2016 to April 2018 in our hospital were recruited in this study. All patients accepted lung function and exhaled nitric oxide test before surgery to evaluate whether accompanied with asthma, improvements after standardized drug therapy in patients with asthma. Read More

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December 2018

[Therapeutic effect of nasal corticosteroids combined with nasal antihistamine on vasomotor rhinitis].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(23):1783-1787

Department of Otolaryngology Head and Neck Surgery, Affiliated Hospital of Guizhou Medical University, Guiyang, 550002, China.

To observe the clinical efficacy of nasal corticosteroids combined with nasal antihistamine in the treatment of vasomotor rhinitis. One hundred and twenty vasomotor rhinitis patients were randomly divided into three groups including budesonide group, azelastine group, and budesonide and azelastine group with 40 cases in each. Nasal spray with nasal corticosteroids and nasal antihistamines was applied for combined treatment group, while the patients in budesonide group and azelastine group were given only nasal corticosteroids and nasal antihistamines, respectively. Read More

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December 2018

[Different phenotypes in patients with chronic sinusitis with bilateral nasal polyps].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(23):1774-1778

Department of Otolaryngology Head and Neck Surgery, Nanjing General Hospital of PLA.

To investigate the clinical features of patients with chronic sinusitis with bilateral nasal polyps. The data of 134 patients with chronic sinusitis with bilateral nasal polyps were analyzed, retrospectively. Based on the results of the histopathological examination, patients were divided into eosinophilic chronic sinusitis with bilateral nasal polyps(ECRSwBNP) group and noneosinophilic chronic sinusitis with bilateral nasal polyps(nonECRSwBNP) group. Read More

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December 2018
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[Analysis of imaging features and treatment strategies of unilateral maxillary sinus and nasal diseases].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(23):1767-1773

Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Key Laboratory of Otolaryngology Head and Neck Surgery, Ministry of Education, Beijing, 100073, China.

To analyze the imaging features of unilateral maxillary sinus nasal lesions and the selection of treatment strategies based on imaging findings for these lesions. The CT and enhanced MRI data of 64 cases of unilateral maxillary sinus and nasal lesions were selected. The imaging findings and surgery approach were observed and recorded. Read More

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December 2018

[Research progress of biologics in the treatment of chronic rhinosinusitis].

Authors:
Y Liu F Yuan

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Oct;32(19):1515-1518

Chronic rhinosinusitis (CRS) is an inflammatory disease of the nasal airways and paranasal sinuses. The condition is defined by more than 12 weeks of nasal obstruction, nasal discharge, facial pain/pressure, and reduced/lost smell. CRS is commonly further classified into 2 subsets based on its clinical phenotype: those with polyps (CRSwNP) and those without (CRSsNP). Read More

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October 2018

[Clinical application of seven-item Eustachian Tube Dysfunction Questionnaire].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Oct;32(19):1483-1486

Department of Otorhinolaryngology Head and Neck Surgery, Shaanxi Provincial People's Hospital.

To investigate the clinical value of the seven-item Eustachian Tube Dysfunction Questionnaire(ETDQ-7) in evaluating Eustachian tube dysfunction before and after treatment. A retrospective analysis of 50 patients with Eustachian tube dysfunction diagnosed. All the patients were given chymotrypsin 4 000 IU and dexamethasone injection 5 mg by blowing through the Eustachian tube under nasal endoscopic guidance once daily for 3-6 consecutive days. Read More

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October 2018

[Analysis of clinical effect of unilateral vidian neurectomy following endoscopic trans-sphenoethmoidal recess approach for allergic rhinitis treatment].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Oct;32(19):1455-1458

Department of Otolaryngology Head and Neck Surgery, Second Hospital of Shanxi Medical University, Taiyuan, 030001, China.

To explore the clinical efficacy of unilateral vidian neurectomy following endoscopic trans-sphenoethmoidal recess approach in treating allergic rhinitis. The clinical data of 80 patients with moderate-severe allergic rhinitis who underwent unilateral vidian neurectomy following endoscopic trans-sphenoethmoidal recess approach were reviewed retrospectively. Visual analogue scale(VAS) was used to assess total symptom scores and nasal symptoms including nasal itching, nasal sneezing, rhinorrhea and nasal congestion. Read More

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October 2018

[Holistic concept of rhinoplasty].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Sep;32(18):1444-1446

In the past 20 years, nasal cavity plasty was operated by the otolaryngologists, while external rhinoplasty was usually implemented by the plastic surgeon respectively. The holistic concept is about the integrity, unity and connection of things and phenomena.Considering the structure and function of the external nose and the nasal cavity as a whole,we review the holistic concept in rhinoplasty and put forward the operation of holistic rhinoplasty, including the nasal cavity plasty and external rhinoplasty, correcting the structure problems of nasal cavity and the external nose deformity, and restoring its physiological and cosmetic functions at the same time. Read More

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September 2018

[Clinical analysis of 9 cases of sarcomatoid carcinoma of the nose].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Sep;32(18):1429-1431

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September 2018
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[Effects of budesonide aerosol inhalation on the immunological functions of peripheral dendritic cells in patients with allergic rhinitis].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Sep;32(18):1391-1395

Department of Otolaryngology Head and Neck Surgery, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China.

To investigate the immunologic functional changes of peripheral dendritic cells (DC) in patients with allergic rhinitis (AR) during the treatment by budesonide aerosol inhalation.25 patients with moderate to severe persistent AR were concluded in current study, and they were given budesonide aerosol inhalation for 8 weeks. AR related nasal symptom scores and indices, peripheral DC counts and percentages as well as their activation before and 4 weeks, 8 weeks after treatment were determined. Read More

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September 2018

[Prevalence of allergy in children with acute rhinosinusitis].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Sep;32(18):1377-1382

Department of Otolaryngology, the Second Affiliated Hospital of Wenzhou Medical University,Wenzhou, 325000, China.

To explore the prevalence of allergy in patients with acute rhinosinusitis (ARS) and evaluate the severity of symptoms in ARS children with or without allergy.Two hundred and seven children (4-12 years of age) with ARS and 85 children of control group were included in our research from June, 2016 to January, 2018. We use questionaire to collect the basic information of pediatric patients. Read More

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September 2018
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[Robotic nasopharyngectomy via combined approach of noseand oral for local recurrent nasopharyngeal carcinoma].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Jul;32(14):1048-1050;1055

Department of Otolaryngology, Sun Yat-sen Memorial Hospital,Sun Yat-sen University, Guangzhou, 510120, China.

Surgery is one of the salvage treatments for recurrent nasopharyngeal carcinoma. The safety and efficacy of Da Vinci's robotic surgery was preliminarily investigated to resect recurrent nasopharyngeal cancer after one-course radiotherapy.Since Oct 2017, Da Vinci surgery system was used to complete the operation of locally recurrent nasopharyngeal carcinoma including two approaches, such as trans oral with soft palate incision and trans oral and nose with soft palate suspended. Read More

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[The effect of the nasal packing material on nasal epithelial cells].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(24):1900-1903

Department of Otolaryngology Head and Neck Surgery,Beijing Tongren Hospital, Capital Medical University, Beijing Institute of Otolaryngology, Key Laboratory of Otolaryngology Head and Neck Surgery (Capital Medical University), Ministry of Education, Beijing, 100730,China.

The aim of this study is to investigate the effect of polyethylene glycol acrylate hybrid hydrogel degradation substance on nasal mucociliary transport system. In our experiment, the complex hydrogel were formed by the combination of different ratios of polyethyleneglycol diacrylate, chitosan and polyvinyl alcohol. The experiment was divided into four groups according to the international standard of medical devices. Read More

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December 2018
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[Application of image navigation assisted nasal endoscopic surgery in optic nerve decompression].

Authors:
L L Shi H T Zhen

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(24):1893-1896

Department of Otolaryngology Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

To explore the application and to evaluate the advantage of image navigation assisted nasal endoscopic surgery in optic nerve decompression. Sixty patients accepted the image navigation assisted nasal endoscopic surgery therapy in optic nerve decompression were included in this retrospective study and followed up for about six months to four years. The visual acuity was improved in 16 cases with visual acuity above light. Read More

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December 2018

[Effect analysis of 60 cases of modified septoplasty].

Authors:
Y B Zhou Y Y Yan F Yu

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(24):1890-1892

Department of Otolaryngology Head and Neck Surgery, Guangzhou 12th People's Hospital, Guangzhou Hospital of Otolaryngology Head and Neck Surgery, Institute of Otolaryngology Head and Neck Surgery of Guangzhou Medical University, Guangzhou,510620, China.

To investigate the clinical efficacy and operative skills of modified septum plasty in the treatment of deviated nasal septum. Retrospectively analyzed the case characteristics, surgical methods, postoperative complications, VAS score and nasal resistance value of 60 patients who received nasal septum surgery. The VAS score of 28 patients who underwent improved septoplasty was significantly lower than that before surgery, and the difference was statistically significant(<0. Read More

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December 2018

[Value of 18F-FDG PET/CT and PET in diagnosing and staging extranodal nasal type natural killer/T-cell lymphoma:A Meta-analysis].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(24):1876-1882

The First Hospital of Lanzhou University.

The aim of this study is to comprehensively evaluate the values of 18F-FDG PET/CT and PET in diagnosing extranodal nasal type natural killer/T cell lymphoma (ENKTL). Studies about ENKTL diagnosed by 18F-FDG PET/CT and PET until June 2018 were searched in the databases such as PubMed, Embase, Cochrane, Web of Science, CNKI, CBM, VIP and Wanfang. Two reviewers independently screened literature and extracted data strictly according to included and excluded criterion, and assessed bias risk by 11 items using QUADAS-2 gulidline. Read More

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December 2018

[Involvement of Th17/Treg imbalance in bacterial biofilm induced chronic rhinosinusitis].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(24):1870-1875

Department of Otolaryngology, Affiliated Eye Ear Nose and Throat Hospital, Fudan University, Shanghai, 200031, China.

The aim of this study is to investigate the involvement of Th17/Treg imbalance in the pathogenesis of bacterial biofilm (BBF) induced chronic rhinosinusitis(CRS). CRS nasal sinus mucosa was collected, and BBF was examined by BacLight/CSLM detection. Forty CRS cases(20 BBF positive cases and 20 negative cases) and 10 controls were enrolled. Read More

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December 2018
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[Nasal irrigation with different concentrations of saline as an adjunctive treatment in allergic rhinitis:A systematic review and Meta-analysis].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(24):1865-1870

Shanxi Medical University, Taiyuan, 030001, China.

To compare the clinical efficacy of different concentrations of saline irrigation in adjuncative treatment of allergic rhinitis by Meta-analysis. According to the inclusion and exclusion criteria, the studies using random controlled trials were retrieved from the Pubmed, Web of science, The Cochrane Library, Embase et al. The Mata-analysis was performed by using RevMan 5. Read More

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December 2018

[Application of image-guided system in endoscopic sinus and skull base surgery].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(24):1856-1859

Department of Otorhinolaryngology Head and Neck Surgery, Huadong Hospital, Fudan University, Shanghai, 200040,China.

To evaluate the applicative value of image-guided system in endoscopic sinus and skull base surgeries. A total of 103 endoscopic surgical procedures were performed.All these procedures were conducted with the utilization of image-guided system, among which there were 92 cases of sinonasal-skull base surgery(including nasal sinuses resection of benign and malignant tumors involving skull base lesions, the cumulative orbital lesion resection of nasal sinus lesions, etc. Read More

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December 2018

[The development of laboratory diagnostic of leprosy using polymerase chain reaction].

Klin Lab Diagn 2018 ;63(1):55-59

DNA-Technology LLC, 115478, Moscow, Russia.

The purpose of study is to develop techniques of laboratory diagnostic of leprosy on the basis of polymerase chain reaction. The techniques were worked through such as extraction of DNA from various clinical material (bioptates and scarifcate of skin, scrapes from mucous surface of nose and trophic ulcers, blood serum). The systems of oligonucleotides were constructed to 16S pRNA and probe for identifcation of Mycobacterium leprae in real-time format for amplifer DT-96 ("The DNA-Technology", Russia). Read More

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January 2018
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A Rare Case of Nasal NK/T-Cell Lymphoma in a Kazakh Man.

Isr Med Assoc J 2018 Dec;20(12):790-791

Department of Medicine, School of Medicine, Nazarbayev University, Astana, Kazakhstan.

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December 2018

Evaluation and Predictors for Nasogastric Tube Associated Pressure Ulcers in Critically Ill Patients.

Isr Med Assoc J 2018 Dec;20(12):731-736

Department of Intensive Care Medicine, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

Background: Nasal device-related pressure ulcers are scarcely addressed in the literature.

Objectives: To assess the prevalence and severity of cutaneous and mucosal nasogastric tube (NGT)-associated pressure ulcers (PU) in critically ill patients and to define predictors for their formation.

Methods: A single center observational study of intensive care unit patients with a NGT for more than 48 hours was conducted. Read More

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December 2018
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Clinical Results of Anti-adhesion Adjuvants after Endonasal Dacryocystorhinostomy.

Korean J Ophthalmol 2018 Dec;32(6):433-437

Department of Ophthalmology and Visual Science, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea.

Purpose: Various absorbable anti-adhesion agents have been used to prevent postoperative synechia formation after endonasal surgery. The purpose of this study was to evaluate the anti-adhesion effects of HyFence and Mediclore after endonasal dacryocystorhinostomy (DCR) compared to a mixed solution of hyaluronic acid and sodium carboxymethylcellulose (Guardix-Sol).

Methods: In this retrospective study, endonasal DCR and silicone tube intubation were performed on 198 eyes of 151 patients. Read More

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December 2018

Effect of high frequency oscillatory high flow nasal cannula on carbon dioxide clearance in a premature infant lung model: A bench study.

Pediatr Pulmonol 2018 Dec 14. Epub 2018 Dec 14.

CHOP Newborn Care at Pennsylvania Hospital, Philadelphia, Pennsylvania.

Objective: This study compared CO clearance in a premature infant lung model connected to a high flow nasal cannula (HFNC) system supplied with oscillatory versus non-oscillatory flow.

Design/methods: The lung model was set to compliance 1.0 mL/cmH O, RR 60 breaths/min, and 6 mL tidal volume. Read More

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December 2018
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A homozygous MITF mutation leads to familial Waardenburg syndrome type 4.

Am J Med Genet A 2018 Dec 14. Epub 2018 Dec 14.

Department of Otolaryngology - Head and Neck Surgery, The Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Waardenburg syndrome (WS) is a genetic disorder characterized by hearing loss and pigmentary abnormalities with variable penetrance. Though heterozygous mutations in MITF are a major cause for Waardenburg syndrome type 2 (WS2), homozygous mutations in this gene and the associated phenotype have been rarely characterized. In this study, we identified a novel p. Read More

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December 2018
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Association of epistaxis with atherosclerotic cardiovascular disease.

Laryngoscope 2018 Dec 13. Epub 2018 Dec 13.

Department of Otorhinolaryngology-Head and Neck Surgery, University Hospital Zurich, Zurich, Switzerland.

Objectives/hypothesis: To investigate the association between epistaxis and atherosclerotic cardiovascular disease.

Study Design: Case-control cohort study.

Methods: This study included patients from the tertiary-care ear, nose, and throat department at the University Hospital of Zurich between December 1, 2016 and June 1, 2017. Read More

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December 2018

Non-destructive Characterization of Eggs Odor in Different Statuses of Fertilization by SPME/GC-MS coupled with Electronic nose.

J Sci Food Agric 2018 Dec 13. Epub 2018 Dec 13.

National Research and Development Center for Egg Processing, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, Hubei, 430070, PR China.

Background: Early and non-destructive identification of fertile (F) eggs is a difficult task in the breeding process of laying hens. The odors emitted from unfertilized (UF), infertile (IF) and F eggs were characterized by SPME/GC-MS and electronic nose (E-nose) to determine their differences by principal component, partial least squares and canonical discriminant analyses.

Results: A total of 14 volatiles were identified in unhatched shell White Leghorn eggs, such as nonanal, decanal, 6-methyl-5-hepten-2-one, 6,10-dimethyl-5,9-Undecadien-2-one, etc. Read More

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December 2018

Immunologic modification in mono- and poly-sensitized patients after sublingual immunotherapy.

Laryngoscope 2018 Dec 13. Epub 2018 Dec 13.

Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University College of Medicine, Seoul, Korea.

Objectives/hypothesis: To compare immunologic modification and treatment outcomes after 2 years of sublingual immunotherapy (SLIT) with house dust mite extracts (HDM) between monosensitized and polysensitized patients with allergic rhinitis.

Study Design: Retrospective cohort study.

Methods: Among the patients who were prospectively enrolled in the SLIT cohort study, patients with allergic rhinitis who were sensitized to HDM and treated with SLIT for at least 2 years were studied. Read More

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December 2018

High-flow nasal cannula oxygen therapy for acute respiratory failure in a non-intensive geriatric setting.

Geriatr Gerontol Int 2018 Dec;18(12):1652-1653

Unit of Geriatrics, Department of Internal Medicine, Azienda Ospedaliera di Cosenza, Cosenza, Italy.

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December 2018

Alternaria-induced barrier dysfunction of nasal epithelial cells: role of serine protease and reactive oxygen species.

Int Forum Allergy Rhinol 2018 Dec 12. Epub 2018 Dec 12.

Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Catholic University of Daegu, Daegu, South Korea.

Background: Upper airway barrier dysfunction has been associated with chronic rhinosinusitis and allergic rhinitis. Alternaria is commonly found in nasal secretion and plays a role in the pathogenesis of airway diseases. The aim of this study was to investigate the effects of Alternaria on the junctional complex of nasal epithelial cells. Read More

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December 2018

Socioeconomic factors impact quality of life outcomes and olfactory measures in chronic rhinosinusitis.

Int Forum Allergy Rhinol 2018 Dec 10. Epub 2018 Dec 10.

Division of Rhinology and Sinus/Skull Base Surgery, Department of Otolaryngology-Head and Neck Surgery, Oregon Health and Science University, Portland, OR.

Background: Healthcare disparities related to socioeconomic factors may adversely impact disease states and treatment outcomes. Among patients with chronic rhinosinusitis (CRS), the impact of socioeconomic factors on outcomes following endoscopic sinus surgery (ESS) remains uncertain.

Methods: Adult patients with refractory CRS were prospectively enrolled into an observational, multi-institutional cohort study between March 2011 and June 2015. Read More

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December 2018

The oculoauriculofrontonasal syndrome: Further clinical characterization and additional evidence suggesting a nontraditional mode of inheritance.

Am J Med Genet A 2018 Dec 10. Epub 2018 Dec 10.

Centre de Génétique et Centre de Référence Anomalies du Développement et Syndromes Malformatifs de l'Interrégion Est, Centre Hospitalier Universitaire Dijon, Dijon, France.

The oculoauriculofrontonasal syndrome (OAFNS) is a rare disorder characterized by the association of frontonasal dysplasia (widely spaced eyes, facial cleft, and nose abnormalities) and oculo-auriculo-vertebral spectrum (OAVS)-associated features, such as preauricular ear tags, ear dysplasia, mandibular asymmetry, epibulbar dermoids, eyelid coloboma, and costovertebral anomalies. The etiology is unknown so far. This work aimed to identify molecular bases for the OAFNS. Read More

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December 2018

Vector field analysis for surface registration in computer-assisted ENT-surgery.

Int J Med Robot 2018 Dec 7:e1977. Epub 2018 Dec 7.

Department of Oto-, Rhino-, Laryngology, 4D-Visualization Laboratory, Innsbruck Medical University, Innsbruck, Austria.

Background: Manual paired-point registration for navigated ENT-surgery is prone to human errors; automatic surface registration is often caught in local minima.

Methods: Anatomical features of the human occiput are integrated into an algorithm for surface registration. A vector force field is defined between the patient and operating room datasets; registration is facilitated through gradient-based vector field analysis optimization of an energy function. Read More

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December 2018

Epidemiology of Facial Fractures among Older Adults: A Retrospective Analysis of a Nationwide Emergency Department Database.

Dent Traumatol 2018 Dec 8. Epub 2018 Dec 8.

Department of Orthodontics, The University of Illinois in Chicago, Chicago, Illinois.

Background/aims: The prevalence of facial fractures among older adults has increased in recent years, and nationwide studies about the epidemiological profile and outcomes of hospital-based ED visits for facial fractures among older adults are scarce. The aim of this study was to provide USA-wide data of hospital-based Emergency Department (ED) visits for facial fractures among older adults, and to investigate the outcomes associated with these visits.

Material And Methods: The Nationwide Emergency Department Sample (NEDS) for the years 2008 to 2014 was used for the present study. Read More

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December 2018

Applying for regulatory approval of a clinical trial of a medical device in the UK - A practical guide.

Br Dent J 2018 Dec;225(11):1033-1036

Department of Orthodontics, Guy's and St Thomas' NHS Foundation Trust, London, UK.

Seeking regulatory and ethical approval is a significant task that must be completed before conducting a clinical trial of a medical device. Currently in the UK, the Integrated Research Application System (IRAS) is a unified system for preparing regulatory, ethical and governance applications for the relevant bodies that must approve health and social research. This article outlines key aspects in planning a clinical trial of a medical device and how applications for approval can be prepared using IRAS. Read More

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December 2018

The Use of Procalcitonin for Prediction of Pulmonary Bacterial Coinfection in Children With Respiratory Failure Associated With Viral Bronchiolitis.

Clin Pediatr (Phila) 2018 Dec 14:9922818816432. Epub 2018 Dec 14.

1 University of Oklahoma Health Science Center, Oklahoma City, OK, USA.

Objectives: Viral bronchiolitis is a frequent cause of pediatric hospitalization and respiratory failure. Procalcitonin (PCT) is a biomarker used to identify serious bacterial infection and can distinguish bacterial and viral infections. Concomitant bacterial pneumonia is not rare in viral bronchiolitis and can lead to a worse clinical course. Read More

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December 2018

Colorimetric Sensor Array for Monitoring CO and Ethylene.

Anal Chem 2018 Dec 14. Epub 2018 Dec 14.

Department of Chemistry , University of Illinois at Urbana-Champaign , 600 South Mathews Avenue , Urbana , Illinois 61801 , United States.

Developing miniaturized and inexpensive detectors remains an important and practical goal for field-deployable monitoring of toxic gases and other bioactive volatiles. CO (a common toxic pollutant) and ethylene (the phytohormone primarily responsible for fruit ripening) share the capability of strong back-π-bonding to low-oxidation-state metal ions, which has proved important in the development of metal-ion-based sensors for these gases. We report herein cumulative colorimetric sensor arrays based on Pd(II)-silica porous microsphere sensors and their application as an optoelectronic nose for rapid colorimetric quantification of airborne CO and ethylene. Read More

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December 2018

Electronic nose dataset for beef quality monitoring in uncontrolled ambient conditions.

Data Brief 2018 Dec 22;21:2414-2420. Epub 2018 Nov 22.

Biology Department, Institut Teknologi Sepuluh Nopember, Jalan Raya ITS, Keputih, Sukolilo, 60111 Surabaya, East Java, Indonesia.

In recent years, the development of a rapid, simple, and low-cost meat assessment system using an electronic nose (e-nose) has been the concern of researchers. In this data article, we provide a time series dataset that was obtained from a beef quality monitoring experiment using an e-nose in uncontrolled ambient conditions. The availability of this dataset will enable discussion on how to deal with noisy e-nose signals and non-optimum sensor array in beef quality monitoring. Read More

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December 2018
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