Search Our Scientific Publications & Authors

J Biomed Mater Res A 2019 Jan 16. Epub 2019 Jan 16.

Institute for Biology and Chemistry of Proteins, Laboratory of Tissue Biology and Therapeutic Engineering (LBTI), CNRS UMR 5305, Lyon, France.

Nasal reconstruction remains a challenge for every reconstructive surgeon. Alloplastic implants are proposed to repair nasal cartilaginous defects but they are often associated with high rates of extrusion and infection and poor biocompatibility. In this context, a porous polymeric scaffold filled with an autologous cartilage gel would be advantageous. Read More

Otolaryngol Clin North Am 2019 Jan 4. Epub 2019 Jan 4.

Department of Otolaryngology-Head and Neck Surgery, Temple University School of Medicine, 3509 North Broad Street, Suite 300, Philadelphia, PA 19140, USA.

Osseointegrated auditory devices (OADs) are hearing devices that use an external receiver/processor that stimulates bone conduction of sound via a titanium prosthesis that is drilled into the bone of the cranium. Since their introduction in 1977, OADs have undergone substantial evolution, including changes in manufacturing of the implant, improvements in the external sound processor, and simplification of implantation techniques. Expansion of criteria for patient candidacy for implantation has occurred corresponding with changes in the implants and processors. Read More

Imaging Sci Dent 2018 Dec 20;48(4):269-275. Epub 2018 Dec 20.

Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Akdeniz University, Antalya, Turkey.

Purpose: The aim of this study was to evaluate the correlations between measurements made using panoramic radiography and cone-beam computed tomography (CBCT) based on certain anatomical landmarks of the jaws, with the goal of preventing complications due to inaccurate measurements in the pre-surgical planning phase of dental implant placement.

Materials And Methods: A total of 56 individuals who underwent panoramic radiography and a CBCT evaluation before dental implant surgery were enrolled in the study. Measurements were performed to identify the shortest vertical distance between the alveolar crest and neighboring anatomical structures, including the maxillary sinus, nasal floor, mandibular canal, and foramen mentale. Read More

World Neurosurg 2018 Dec 19. Epub 2018 Dec 19.

Department of Otolaryngology-Head and Neck Surgery, University of Colorado School of Medicine, Aurora, Colorado, USA; Department of Neurosurgery, University of Colorado School of Medicine, Aurora, Colorado, USA. Electronic address:

Objective: The Medpor porous polyethylene implant is reported to be safe and effective for sellar reconstruction after transsphenoidal surgery (TSS). However, we have observed several cases of delayed chronic sphenoid sinusitis related to the implant. The purpose of this study is to describe the presentation and management of implant-related sphenoid sinusitis after sellar reconstruction. Read More

Acta Biomater 2019 Feb 14;85:157-171. Epub 2018 Dec 14.

Centre for Biomaterials in Surgical Reconstruction and Regeneration, Division of Surgery & Interventional Science, University College London, London NW3 2PF, United Kingdom. Electronic address:

Increasing evidence suggests the contribution of the dynamic mechanical properties of the extracellular matrix (ECM) to regulate tissue remodeling and regeneration. Following our recent study on a family of thermoresponsive 'stiffness memory' elastomeric nanohybrid scaffolds manufactured via an indirect 3D printing guided thermally-induced phase separation process (3D-TIPS), this work reports in vitro and in vivo cellular responses towards these scaffolds with different initial stiffness and hierarchically interconnected porous structure. The viability of mouse embryonic dermal fibroblasts in vitro and the tissue responses during the stiffness softening of the scaffolds subcutaneously implanted in rats for three months were evaluated by immunohistochemistry and histology. Read More

Int J Pediatr Otorhinolaryngol 2019 Jan 11;116:79-83. Epub 2018 Oct 11.

Cochlear Implant Department, Great Ormond Street Hospital, London, United Kingdom. Electronic address:

Objectives: Auditory neuropathy spectrum disorder (ANSD) is an audiological diagnosis characterised by hearing dysfunction in the presence of intact outer hair cell function in the cochlea. ANSD is thought to account for 7-10% of all childhood permanent hearing impairment, and can result from a range of pathological processes. This paper describes the rationale, methods and findings from the aetiological investigation of ANSD. Read More

Cleft Palate Craniofac J 2018 Dec 13:1055665618817669. Epub 2018 Dec 13.

4 American Craniofacial Associates, Athens, Greece.

Introduction:: Skeletal reconstruction in severe grades of hemifacial microsomia (HFM) continues to be challenging. Traditional techniques of autografts and osseous distraction for reconstruction of the glenoid fossa, condyle, and ramus can fall short of expectations and can create new problems. This intercontinental study analyzes the role of alloplastic skeletal rehabilitation in severe HFM. Read More

Eur Arch Otorhinolaryngol 2018 Dec 7. Epub 2018 Dec 7.

Department of Otorhinolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, 2100, Copenhagen, Denmark.

Objective: To present long-term data on the Wide Ponto implant bone-anchored hearing system (BAHS) in regards to implant stability, soft tissue reaction and implant loss for two case series undergone either the tissue reduction- or the tissue preservation surgical technique.

Methods: Comparison of two consecutive, prospective case series. Each case series enrolled 24 patients. Read More

Cochlear Implants Int 2019 Mar 22;20(2):57-61. Epub 2018 Nov 22.

a Cochlear Implant Department , Royal National Throat Nose and Ear Hospital , London , UK.

Objectives: It is recognised that CT can be used to determine the cochlear duct length (CDL) when selecting an electrode for cochlear implantation. It is the practice of our institution to routinely use MRI as the sole modality of pre-operative imaging in the assessment of children referred for consideration of cochlear implantation. We therefore wanted to determine whether MRI could be reliably used to determine cochlear duct length. Read More

Ann Otol Rhinol Laryngol 2018 Nov 21:3489418812898. Epub 2018 Nov 21.

2 Department of Neuroscience DNS, Maxillofacial Surgery Unit, University of Padova, Padova, Italy.

Objectives:: Displacement of dental materials into the maxillary sinus occurs in daily dental practice; dental implants have become a new common foreign body (FB), as implantation has become routine. The main goal of the present study was to analyze an original series of patients consecutively treated for maxillary sinus FBs. A secondary goal was to propose a decision-making flowchart on the basis of the authors' experience and a critical analysis of literature to select the most appropriate surgical approach. Read More

Int J Radiat Oncol Biol Phys 2018 Nov 17. Epub 2018 Nov 17.

Department of Radiation Oncology, Radboudumc, Nijmegen, The Netherlands.

Purpose: To evaluate the efficacy of modern image guided brachytherapy for squamous cell carcinoma of the nasal vestibule, to explore tumor volume as a prognostic factor for local and regional recurrence, and to assess patient satisfaction with nasal function and appearance after treatment.

Methods And Materials: In a retrospective analysis, we reviewed the medical records of 102 patients with Wang T1-T2 nasal vestibule cancer treated at a single institution with brachytherapy as the sole treatment. Median follow-up time was 42 months (range, 3-210 months). Read More

Expert Rev Clin Pharmacol 2018 Nov 20. Epub 2018 Nov 20.

a Feinberg School of Medicine, Department of Otolaryngology - Head and Neck Surgery , Northwestern University , Chicago , IL , USA.

Introduction: Chronic rhinosinusitis (CRS) is a broad heterogeneous inflammatory disorder of the nose and paranasal sinuses, resulting from the dysfunctional interplay between host immunity, defective epithelial barrier, and environmental factors. CRS with nasal polyps (CRSwNP) is considered a more severe clinical phenotype with greater burden of symptoms and higher relapse rate, especially with comorbid asthma or aspirin sensitivity. Available treatment options after endoscopic sinus surgery (ESS) - systemic corticosteroids or revision surgery - have significant risks and limitations. Read More

J Indian Prosthodont Soc 2018 Oct-Dec;18(4):356-363

Department of Prosthodontics, Kalinga Institute of Dental Sciences, KIIT University, Bhubaneswar, Odisha, India.

Purpose: Variation of dimensions of the nasopalatine canal and anterior maxillary bone thickness vary in relation to age, gender, edentulism, and ethnicity; thorough knowledge with regard to these landmarks is of vital importance prior to surgical procedures such as implant placement and local anesthesia in the anterior maxilla. Cone beam computerized tomography (CBCT) aids in accurate treatment planning in such situations.

Subjects And Methods: A total of 300 participants were selected by the inclusion and exclusion criteria. Read More

Int J Oral Maxillofac Implants 2018 Nov/Dec;33(21):1351-1361

Purpose: To evaluate the 5-year clinical outcomes for implants placed in a staged sinus floor elevation (SFE) procedure and to compare three patient groups with sinus grafts with three different ratios of bovine bone mineral (BBM) and autogenous bone (AB) mixture.

Materials And Methods: A 5-year prospective cohort study was conducted on 81 patients with 119 staged SFEs non-randomly distributed to three groups based on the origin of the AB and the mixture ratio with BBM: group 1 (locally harvested AB [LHB] from osteotomy sites + BBM, ratio: 1:10), 31 patients, 37 SFEs; group 2: (LHB + intraorally harvested peripheral AB [IHPB] from retromolar/chin region + BBM, ratio: 1:4), 22 patients, 29 SFEs; and group 3 (LHB + extraorally harvested peripheral AB [EHPB] from iliac crest/tibia + BBM, ratio 1:1), 28 patients, 53 SFEs. After graft healing (5 to 7 months), 284 dental implants (group 1: 76, group 2: 61, group 3: 147 [overall: 2. Read More

Int J Oral Maxillofac Implants 2018 Nov/Dec;33(6):1345-1350

Bovine-derived bone mineral demonstrated good osteoconductive properties as grating material for maxillary sinus floor elevation, but the long-term behavior of this material has not been reported. The purpose of this report was to analyze and compare histomorphometric measurements of new bone, bone graft, and medullar spaces 6 months, 12 months, and 20 years after grafting. In the grafted area, the amount of mineralized bone was 16. Read More

Int J Oral Maxillofac Implants 2018 Nov/Dec;33(6):1305-1311

Purpose: To evaluate the effectiveness and predictability of a novel biomechanical, minimally invasive bone instrumentation technique that enhances bone density through compaction grafting, called osseous densification, and allows for transcrestal sinus membrane elevation and augmentation with simultaneous implant placement.

Materials And Methods: Patients who were consecutively treated with the bone densification and transcrestal sinus augmentation technique and were followed up in three treatment centers between May 2012 and September 2017 were included in this retrospective study. The summary statistics are presented as means for continuous variables and percentages for categorical variables. Read More

J Prosthet Dent 2018 Nov;120(5):780-786

Professor, Department of Implantology and Periodontology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.

Statement Of Problem: Maxillofacial prostheses, especially those supported by endosseous implants, are regarded as a viable, secure treatment for the reconstruction of facial defects to restore quality of life. The long-term quality of life of patients treated with facial prostheses with different retentive systems is unclear.

Purpose: The purpose of this clinical study was to assess the long-term quality of life of patients treated with facial prostheses with different retentive systems over a 14-year period at a Dutch oral and maxillofacial surgery unit. Read More

Med Lett Drugs Ther 2018 Sep;60(1555):151-152

Cochlear Implants Int 2018 Oct 31:1-3. Epub 2018 Oct 31.

a Cochlear Implant Department , Royal National Throat, Nose and Ear Hospital , Gray's Inn Road, London WC1X 8DA , UK.

Introduction: We have observed a small number of patients with cochlear implants who have a tendency to develop recurrent seromas overlying the implant package.

Methods: Five patients with a current or previous history of recurrent seromas presenting for review over a three-month period were identified. A retrospective review of their case notes was undertaken. Read More

Fed Regist 2018 Oct;83(208):54007-10

The Food and Drug Administration (FDA or we) is classifying the active implantable bone conduction hearing system into class II (special controls). The special controls that apply to the device type are identified in this order and will be part of the codified language for the active implantable bone conduction hearing system's classification. We are taking this action because we have determined that classifying the device into class II (special controls) will provide a reasonable assurance of safety and effectiveness of the device. Read More

J Oral Maxillofac Surg 2018 Sep 27. Epub 2018 Sep 27.

Director, Head and Neck Cancer Program, Legacy Good Samaritan Medical Center, Portland; Consultant, Head and Neck Institute, Portland, OR.

Purpose: Previously described techniques for microvascular fibula reconstruction of Brown Class II to IV maxillectomy defects are complex, require multiple osteotomies, result in a short pedicle, and inadequately reconstruct the dental alveolus in preparation for endosseous implants. This report describes a simplified technique for Brown Class II to IV defects that re-creates facial support, allows for dental reconstruction with appropriately positioned implants, and maintains adequate pedicle length.

Materials And Methods: A retrospective chart review was performed of all patients with Brown Class II to IV maxillectomy defects immediately reconstructed with a biaxial double-barrel fibula flap technique. Read More

Rev Esc Enferm USP 2018 Oct 11;52:e03363. Epub 2018 Oct 11.

Universidade Federal de São Paulo, Escola Paulista de Enfermagem, Departamento de Enfermagem em Saúde da Mulher, São Paulo, Brasil.

Objective: To analyze the association between the surgical characteristics of breast implants, time elapsed since surgery, access route, implant placement and implanted volume and variables related to breastfeeding, type, first 'milk let-down', breast engorgement, pain, lesion, milk production and use of galactagogues.

Method: A prospective cohort carried out during the hospital stay (12 to 72 hours after delivery), home care (5thto 7thday after delivery) and telephone contact (between the 30thand 32ndday postpartum) of 115 postpartum women with breast implants between 2015 and 2017.

Results: The first evaluation identified more frequent use of oral galactagogues (p=0. Read More

JAMA Otolaryngol Head Neck Surg 2018 Dec;144(12):1145-1152

Department of Otolaryngology-Head and Neck Surgery, Seoul St Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea.

Importance: Studies have shown the controllability and porosity of polycaprolactone as well as the use of 3-dimensional (3-D) printing for nasal reconstruction in animal models. The utility of polycaprolactone with 3-D technology in nasal cartilaginous framework reconstruction in humans remains unknown.

Objective: To investigate the safety and efficacy of 3-D printed, bioresorbable polycaprolactone nasal implants. Read More

Mol Imaging Radionucl Ther 2018 Oct;27(3):144-145

Acıbadem Mehmet Ali Aydınlar University Faculty of Medicine, Department of Nuclear Medicine, İstanbul, Turkey

Primary malignant melanoma occurs most often in the skin and much less frequently in the choroid layer of the eyes, in the leptomeninges, oral cavity, nasal mucosa, pharynx, esophagus, bronchus, under the nail and vaginal or anorectal mucosa. Primary melanoma of the gastrointestinal tract has been confirmed for lesions occurring in the esophagus, stomach, small bowel, and anorectum through several published reports, as these are the areas where melanocytes normally exist. The occurrence of primary malignant melanoma in the colon is relatively rare, because melanocytes are embryologically absent in the large bowel. Read More

J Am Acad Audiol 2018 Oct;29(9):814-825

Children's Ear, Nose and Throat Specialists, Children's Hospital Medical Office Building, Knoxville, TN.

Background: Cochlear implant (CI) users are affected more than their normal hearing (NH) peers by the negative consequences of background noise on speech understanding. Research has shown that adult CI users can improve their speech recognition in challenging listening environments by using dual-microphone beamformers, such as adaptive directional microphones (ADMs) and wireless remote microphones (RMs). The suitability of these microphone technologies for use in children with CIs is not well-understood nor widely accepted. Read More

Am J Orthod Dentofacial Orthop 2018 10;154(4):462-463

Goiânia, Goiás, Brazil.

Braz Oral Res 2018 13;32:e86. Epub 2018 Sep 13.

Department of Dental Materials and Prosthodontics, Aracatuba Dental School, Universidade de São Paulo, Araçatuba, SP, Brazil.

This study compared the survival rate of dental implants, amount of marginal bone loss, and rates of complications (biological and prosthetic) between short implants and long implants placed after maxillary sinus augmentation. This systematic review has been registered at PROSPERO under the number (CRD42017073929). Two reviewers searched the PubMed/MEDLINE, Embase, LILACS, and Cochrane Library databases. Read More

Int J Oral Maxillofac Implants 2018 Sep/Oct;33(5):1149-1154

Purpose: To evaluate the sinus membrane perforation and implant survival rate after crestal minimally invasive sinus floor augmentation using hydraulic pressure and vibrations.

Materials And Methods: In this retrospective single cohort study, all patients who underwent minimally invasive sinus floor augmentation between 2007 and 2015 using hydraulic pressure and vibrations were included. The sinus membrane is elevated by physiologic saline at 1. Read More

Int J Oral Maxillofac Implants 2018 Sep/Oct;33(5):1136-1139

Purpose: This observational study was based on a series of clinical cases in which failure of sinus augmentations occurred in patients who received prophylactic clindamycin therapy.

Materials And Methods: Between the years 2006 and 2010, a retrospective observational study was performed. The study consisted of 1,874 patients (723 males and 1,151 females) in whom sinus augmentations were performed prior to placement of dental implants. Read More

Int J Oral Maxillofac Implants 2018 Sep/Oct;33(5):995-1002

Purpose: To evaluate the mean amount of intrasinus bone obtainable with the osteotome technique for transcrestal maxillary sinus elevation combined with simultaneous implant insertion, with and without the use of grafting materials.

Materials And Methods: A review was conducted on PubMed, Scopus, and Cochrane central databases. Only human studies in which implant placement was contextual to the sinus elevation procedure, without additional crestal regenerative procedures and with a minimum 1-year follow-up, were selected. Read More

Eur Arch Otorhinolaryngol 2018 Nov 18;275(11):2667-2674. Epub 2018 Sep 18.

Department of Otolaryngology Head and Neck Surgery, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiaotong University, No 639 Zhizaoju Road, Shanghai, 200011, China.

Purpose: To investigate the outcomes of cochlear implantation in patients with neurofibromatosis type 2 (NF2), and to discuss the current management strategy for NF2 patients.

Methods: The medical records of NF2 patients who received cochlear implants (CI) at our center between 2012 and 2016 were retrospectively reviewed. Pre-operative hearing status, tumor status, treatment of tumors, and auditory outcomes post-implantation were evaluated. Read More

Facial Plast Surg 2018 Oct 18;34(5):545-550. Epub 2018 Sep 18.

Department of Otorhinolaryngology, Head and Neck Surgery, Ludwig Maximilian University of Munich, Munich, Germany.

The safety and effectiveness of an absorbable implant for lateral cartilage support have been recently demonstrated in subjects with nasal valve collapse (NVC) at 12 months postprocedure. This follow-up study aimed to assess whether the safety and effectiveness of the implant persist in these patients for 24 months after the procedure. Thirty subjects with Nasal Obstruction Symptom Evaluation (NOSE) score ≥ 55 and isolated NVC were treated; 14 cases were performed in an operating suite under general anesthesia and 16 cases were performed in a clinic-based setting under local anesthesia. Read More

Acta Biomater 2018 Oct 15;80:188-202. Epub 2018 Sep 15.

UCL Centre for Nanotechnology and Regenerative Medicine, Division of Surgery & Interventional Science, University College London, London NW3 2PF, UK. Electronic address:

Cell and tissue stiffness is an important biomechanical signalling parameter for dynamic biological processes; responsive polymeric materials conferring responsive functionality are therefore appealing for in vivo implants. We have developed thermoresponsive poly(urea-urethane) nanohybrid scaffolds with 'stiffness memory' through a versatile 3D printing-guided thermally induced phase separation (3D-TIPS) technique. 3D-TIPS, a combination of 3D printing with phase separation, allows uniform phase-separation and phase transition of the polymer solution at a large interface of network within the printed sacrificial preform, leading to the creation of full-scale scaffolds with bespoke anatomical complex geometry. Read More

BMJ Open 2018 Sep 12;8(9):e021720. Epub 2018 Sep 12.

evidENT, UCL Ear Institute, Royal National Throat, Nose and Ear Hospital, London, UK.

Objectives: Hearing loss is an area of unmet need, and industry is targeting this field with a growing range of surgically implanted hearing devices. Currently, there is no comprehensive UK registry capturing data on these devices; in its absence, it is difficult to monitor clinical and cost-effectiveness and develop national policy. Recognising that developing such a registry faces considerable challenges, it is important to gather opinions from stakeholders and patients. Read More

Zhonghua Kou Qiang Yi Xue Za Zhi 2018 Sep;53(9):645-647

Departmant of Stomatology, ChuiYangLiu Hospital Affliated to Tsinghua University, Beijing 100022, China.

Sinus floor elevation was needed in 11 patients having 15 implant sites with the residual bone height (RBH) was less than 10 mm in the posterior maxillary region from Feb to May 2017. The RBH ranged from 3.10 to 8. Read More

JAMA Otolaryngol Head Neck Surg 2018 Oct;144(10):876-882

Sheffield City Council, Sheffield, United Kingdom.

Importance: Evidence has linked age-related hearing impairment (ARHI) with cognitive decline; however, very few studies (none in the United Kingdom) explore this link in large well-characterized groups of community-dwelling individuals.

Objective: To investigate the link between ARHI and cognitive decline using a cohort of elderly individuals from the United Kingdom and explore untreated hearing loss and social isolation as potential explanations for the observed link.

Design, Setting, And Participants: This cross-sectional analysis of wave 7 (June 2014 through May 2015) of the English Longitudinal Study of Ageing (ELSA) sampled men and women 50 years or older and living in the United Kingdom in a community setting. Read More

Biomed Res Int 2018 13;2018:6562958. Epub 2018 Aug 13.

Oral and Maxillofacial Surgery, Department of Otolaryngology, Tel-Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv 64239, Israel.

Nowadays it is possible to perform an optimal implant placement and to achieve a good long-term prognosis for an implant-borne prosthesis in the grafted posterior maxilla. This study evaluates the efficiency of one-stage piezosurgery by using as graft material a combination of particulate bovine bone substitutes with platelet-rich fibrin to achieve sinus lift. We included in this study 14 cases of one-stage sinus lift surgeries during which we placed 30 standard implants. Read More

Front Neurosci 2018 31;12:501. Epub 2018 Jul 31.

VetImaging, VetCore Facility for Research, University of Veterinary Medicine, Vienna, Austria.

Design and implantation of bionic implants for restoring impaired hair cell function relies on accurate knowledge about the microanatomy and nerve fiber pathways of the human inner ear and its variation. Non-destructive isotropic imaging of soft tissues of the inner ear with lab-based microscopic X-ray computed tomography (microCT) offers high resolution but requires contrast enhancement using compounds with high X-ray attenuation. We evaluated different contrast enhancement techniques in mice, cat, and human temporal bones to differentially visualize the membranous labyrinth, sensory epithelia, and their innervating nerves together with the facial nerve and middle ear. Read More

Med Sci Monit 2018 Aug 14;24:5645-5652. Epub 2018 Aug 14.

Department of Dental Surgery, Wrocław Medical University, Wrocław, Poland.

BACKGROUND Short dental implants are considered an alternative method of treatment to the maxillary sinus elevation and bone augmentation procedure at the sites of a reduced alveolar ridge height. The aim of the study was to determine the most effective therapeutic approach for a single tooth replacement in a reduced maxillary alveolar crest. MATERIAL AND METHODS We enrolled 30 partially edentulous patients having a residual crestal height of 6 mm and a minimal width of the alveolar ridge of 6-7 mm: 15 patients received regular dental implants (OsseoSpeed™ L11 Ø4 mm and L13 Ø4 mm) and the implantation was preceded by the sinus lift procedure from a lateral window approach with the application of a xenogeneic bone graft, whereas the remaining 15 patients received short implants (OsseoSpeed™ L6 mm Ø4 mm) without the sinus lift and augmentation procedure. Read More

Iran J Otorhinolaryngol 2018 Jul;30(99):185-188

Department of Audiology, School of Paramedical Sciences, Mashhad University of Medical Sciences, Mashhad, Iran.

Introduction: Electrically evoked compound action potential (ECAP) is an objective auditory response that can be used in the programing of cochlear implants. The aims of this study were to monitor ECAP thresholds and auditory, language and speech progress for 6 months after cochlear implant surgery and to evaluate any relationship between them.

Materials And Methods: Ten children with a mean age of 4. Read More

Laryngoscope Investig Otolaryngol 2018 Jun 25;3(3):156-161. Epub 2018 May 25.

Department of Otolaryngology-Head and Neck Surgery University of North Carolina at Chapel Hill Chapel Hill North Carolina U.S.A.

Objective: To examine biocompatibility and absorption profile of a poly (L-lactide-co-D,L-lactide) 70:30 nasal implant.

Methods: In an ovine model, 66 rod-shaped absorbable implants were placed in 11 nasal dorsa. The sheep were sacrificed at 1. Read More

Biomed Res Int 2018 27;2018:9430989. Epub 2018 Jun 27.

Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Rome, Italy.

Objectives: To evaluate the performances of six different bone substitute materials used as graft in maxillary sinus augmentation by means of histological and histomorphometric analysis of bone biopsies retrieved from human subjects after a 6-month healing period.

Materials And Methods: Six consecutive patients (3 males, 3 females, aged 50-72 years), healthy, nonsmokers, and with good oral hygiene, presenting edentulous posterior maxilla with a residual bone crest measuring ≤ 4 mm in vertical height and 3 to 5 mm in horizontal thickness at radiographic examination, were selected to receive sinus augmentation and delayed implant placement. Under randomized conditions, sinus augmentation procedures were carried out using mineralized solvent-dehydrated bone allograft (MCBA), freeze-dried mineralized bone allograft (FDBA), anorganic bovine bone (ABB), equine-derived bone (EB), synthetic micro-macroporous biphasic calcium-phosphate block consisting of 70% beta-tricalcium phosphate and 30% hydroxyapatite (HA--TCP 30/70), or bioapatite-collagen (BC). Read More

Exp Clin Psychopharmacol 2018 Dec 23;26(6):570-581. Epub 2018 Jul 23.

National Addiction Centre.

The technology for delivering opioid pharmacotherapy (OPT) is expanding. It is important to know what OPT patients think of these developments and to find ways of enabling patients and clinicians to make informed decisions about which biodelivery system to choose. We explored the views of current and former OPT patients with a history of heroin use to identify factors influencing their preferences regarding routes of OPT administration. Read More

Biomed Res Int 2018 21;2018:2829163. Epub 2018 Jun 21.

Department of Oral Implants, School of Stomatology, State Key Laboratory of Military Stomatology, National Clinical Research Center for Oral Diseases, Shaanxi Engineering Research Center for Dental Materials and Advanced Manufacture, Fourth Military Medical University, Xi'an, Shaanxi 710032, China.

Objective: The aim of this study is to quantify the nonlinear mechanical behavior of the Schneiderian membrane.

Methods: Thirty cadaveric maxillary sinus membrane specimens were divided into the elongation testing group and the perforation testing group. Mechanical experimental measurements were taken via ex vivo experiments. Read More

J Orthop Translat 2018 Jul 27;14:57-62. Epub 2018 Jun 27.

Shanghai Key Laboratory of Orthopaedic Implants, Department of Orthopaedics, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, People's Republic of China.

Background: Surgical masks (SMs) are used to reduce bacterial shedding from the mouth, nose and face. This study aimed to investigate whether SMs may be a potential source of bacterial shedding leading to an increased risk of surgical site infection.

Methods: Bacterial contamination of the SMs was tested by making an impression of the external surface of the mask on sterile culture media immediately. Read More

Ann Plast Surg 2018 Nov;81(5):516-522

Department of Plastic, Aesthetic and Reconstructive Surgery, Singapore General Hospital, Singapore.

Background: A complete release of the transverse nasalis aponeurotic fibers (TNAFs) during Asian rhinoplasty is critical for accurate positioning of the nasal implant and lengthening of the short nose. The objectives of this article are to clarify the anatomy of the TNAFs using cadaveric dissections and to present the clinical results after complete TNAF release in Asian rhinoplasty.

Methods: An anatomical dissection was performed in 8 cadavers to study the TNAFs, specifically the origin, insertion, and boundary of the TNAFs and the effect of the TNAF release on nasal length. Read More

J Craniofac Surg 2018 Nov;29(8):e774-e777

Kies-U Plastic Surgery Clinic, Seoul, Republic of Korea.

Background: In recent years, efficacy of 3-dimensional (3D) simulation, in preoperative planning of aesthetic and reconstructive surgeries and prediction of the postoperative result, has been reported in many clinical studies. Especially in rhinoplasty, it can be used not only for prediction the outcome but also for fabricating implants that will strictly match with the anatomical needs of patient.

Clinical Report: A 30-year-old male after traffic accident visited emergency room complaining on painful swelling and contour deformity of nose. Read More

J Craniofac Surg 2018 Sep;29(6):e591

Department of Surgery and Integrated Clinics, Faculty of Dentistry of Araçatuba, UNESP, São Paulo, Brazil.

The migration of a dental implant into the maxillary sinus is an uncommon event of occurrence. Disrespect for concepts of implantology, low alveolar bone density at the site, high incidence of masticatory force in posterior region, and clinical intercurrences predispose to failure in rehabilitation. Read More

J Ophthalmol 2018 20;2018:8539689. Epub 2018 Jun 20.

Department of Ophthalmology and Visual Science, Eye, Ear, Nose, and Throat Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

Objective: To evaluate and compare the clinical effects of Ahmed glaucoma valves (AGVs) and EX-PRESS implants on glaucoma secondary to silicone oil (SO) emulsification.

Methods: A retrospective case-series study was designed. A total of 23 eyes with late intraocular pressure (IOP) elevation secondary to SO emulsification were included in the study. Read More