Search Our Scientific Publications & Authors

Materials (Basel) 2021 Apr 6;14(7). Epub 2021 Apr 6.

Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Arcavacata di Rende, 87036 Cosenza, Italy.

In the last years, neurological diseases have resulted in a global health issue, representing the first cause of disability worldwide. Current therapeutic approaches against neurological disorders include oral, topical, or intravenous administration of drugs and more invasive techniques such as surgery and brain implants. Unfortunately, at present, there are no fully effective treatments against neurodegenerative diseases, because they are not associated with a regeneration of the neural tissue but rather act on slowing the neurodegenerative process. Read More

Int J Environ Res Public Health 2021 Apr 3;18(7). Epub 2021 Apr 3.

Department of Oral and Maxillofacial Surgery/Oral Pathology and 3D Innovation Lab, Amsterdam UMC, 1081 HZ Amsterdam, The Netherlands.

The aim of this systematic review was to gather the clinical and laboratory applications of CAD/CAM technology for preoperative planning, designing of an attachment system, and manufacturing of nasal prostheses. According to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, an electronic search was carried out. Only human clinical studies involving digital planning for the rehabilitation of facial defects were included. Read More

Injury 2021 Apr 1. Epub 2021 Apr 1.

R Adams Cowley Shock Trauma Center, Department of Orthopaedics, University of Maryland School of Medicine, Baltimore, Maryland, USA. Electronic address:

Objective: Infection after fracture fixation is a potentially devastating outcome, and surgical management is frequently unsuccessful at clearing these infections. The purpose of this study is to determine if factors can be identified that are associated with treatment failure after operative management of a deep surgical site infection.

Methods: We retrospectively reviewed the billing system at a Level I trauma center between March 2006 and December 2015. Read More

Facial Plast Surg 2021 Apr 14. Epub 2021 Apr 14.

Madison ENT and Facial Plastic Surgery, New York, New York.

The aim of the study is to report outcomes after treatment of nasal valve collapse with a bioabsorbable nasal implant. It involves two prospective, multicenter, post-market studies evaluating long-term effectiveness of the LATERA implant for severe to extreme nasal obstruction. Participants underwent implant alone or with concomitant inferior turbinate reduction (ITR) and/or septoplasty. Read More

Gland Surg 2021 Mar;10(3):1010-1017

Department of Neurosurgery, Qilu Hospital of Shandong University, Jinan, China.

Background: Bioresorbable alloplastic implants have become desirable as a rigid buttress for reconstructing skull base defects. This study aimed to describe the use of a biodegradable plate (PolyMax RAPID) in skull base repair of endoscopic endonasal pituitary surgery and to investigate the clinical outcome and safety of this novel method.

Methods: Between January 2019 and January 2020, 22 patients with pituitary adenomas who underwent endoscopic skull base repair with a Polymax RAPID plate were included. Read More

Acta Neurochir (Wien) 2021 Apr 7. Epub 2021 Apr 7.

Department of Otology, Auditory Implants and Skull Base Surgery, Sorbonne Université-APHP6, Groupe Hospitalier Pitié-Salpêtrière, 75013, Paris, France.

Background: Decision-making for large sporadic vestibular schwannomas (VS) resection guided by the intraoperative change in supramaximal facial nerve (FN) amplitude and latency response to optimize post-operative FN outcome.

Methods: Prospectively study of 43 patients, from January to December 2018, of large sporadic VS with preoperative normal FN function at our center. Tumors were removed through retrosigmoid (81%) or translabyrinthine (19%) approaches with FN monitoring. Read More

Int J Periodontics Restorative Dent 2021 Mar-Apr;41(2):261-268

This study aimed to rehabilitate shortened maxillary dental arch with splinted crowns by connecting ultra-short implants with longer ones. In the posterior maxilla of 11 patients, one 10-mm (n = 11) and one or two ultra-short 4-mm (n = 17) dental implants were inserted. The insertion torque was lower than 20 Ncm in 55% of the 10-mm implants and in 94% of the 4-mm implants ( > . Read More

Ear Nose Throat J 2021 Mar 23:145561321990188. Epub 2021 Mar 23.

Department of Otolaryngology, Izmir Research and Training Hospital.

Objective: To investigate the effects of the mechanical trauma to the round window, a model electrode inserted into the scala tympani on the cochlear reserve, and the efficacy of topical steroids in preventing hearing loss.

Materials And Methods: 21 male Wistar Albino rats were equally categorized into three groups. In all groups an initial mechanical injury to round window was created. Read More

Ear Nose Throat J 2021 Mar 23:145561321996837. Epub 2021 Mar 23.

Department of Otorhinolaryngology, 13707National Hospital Organization Osaka, Osaka City, Japan.

Cochlear implants improve the quality of life of patients with bilateral severe sensorineural hearing loss. Normally, patients with cochlear implants can continue to use the devices for years without any complications. However, equipment failure or infection at the implant site could develop in some patients, and this might often necessitate implant replacement. Read More

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2021 Mar;56(3):242-248

Head and Neck Cosmetic Surgery Center of Beijing Plastic Surgery Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100144, China.

To explore the feasibility of reconstruction of nasal tip with septal cartilage and auricular cartilage. From September 2018 to October 2019, 17 patients (two males and fifteen females) with low noses underwent rhinoplasty under general anesthesia. The age of the patients ranged from 19 to 39, with an average of 27 years old. Read More

Facial Plast Surg 2021 Mar 16. Epub 2021 Mar 16.

Division of Facial Plastic and Reconstructive Surgery, Department of Otolaryngology, Head and Neck Surgery, University of Minnesota, Minneapolis, Minnesota.

As the face ages, there is thinning of the epidermis, volume loss and rearrangement of the soft tissues, and malabsorption of the skeletal framework. It is essential to have a thorough understanding of the aging process for successful facial augmentation and rejuvenation. Alloplastic implants can be used to provide a long-lasting solution for augmentation of skeletal deficiencies, restoration of facial irregularities, and rejuvenation of the face. Read More

Vestn Otorinolaringol 2021 ;86(1):30-35

North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, Russia.

The Aim Of The Study: Was to study the possibility of using a battery of psychoacoustic tests to assess the tuning of the cochlear implant processor (CI) in deaf patients.

Methodology: The study involved 60 prellingually deaf patients aged 10 to 23 years with oral speech skills. To assess the quality of the CI processor tuning, in addition to traditional methods, a special battery of psychoacoustic tests was used. Read More

Vestn Otorinolaringol 2021 ;86(1):6-10

Saint Petersburg Research Institute for Ear, Throte, Nose and Speech, Saint Petersburg, Russia.

Despite the rare incidence of Van der Hoeve syndrome in the population, the problem of treating patients with this type of disease is important for modern science and practical medicine. One of the most difficult tasks in treatment is to improve the quality of hearing. The world scientific community lacks a unified coordinated approach to the methods of auditory rehabilitation of patients with Van der Hoeve syndrome. Read More

Otol Neurotol 2021 04;42(4):524-531

Department of Otolaryngology Head and Neck Surgery, Sino-French Joint Clinic Research Center on Otology and Neuro-Otology, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiaotong University.

Objective: To study the surgical results, intracochlear position of the electrode array (EA) and auditory performance of the LISTENT LCI-20PI cochlear implant device, and daily use status at 3 years.

Study Design: A retrospective study.

Setting: A single-tertiary referral center. Read More

J Oral Implantol 2021 Feb;47(1):25-29

Department of Periodontology, Indiana University School of Dentistry, Indianapolis, Ind.

The most commonly reported complication during the sinus elevation surgical procedure is the perforation of the Schneiderian membrane. The aim of this retrospective study was to compare the rate of sinus membrane perforation during lateral window augmentation using either conventional sinus curettes or medical-grade polyurethane sponges. This retrospective study included patients who received a lateral window approach for sinus floor elevation. Read More

BMJ Case Rep 2021 Mar 3;14(3). Epub 2021 Mar 3.

Otolaryngology & Radiology Department, Sunderland Royal Hospital, Sunderland, UK.

We report a case of a 54-year-old woman with saline-based breast implants who presented to the ear, nose and throat neck lump clinic with a 2-week history of bilateral neck lumps. She was found to have multiple palpable cervical lymph nodes bilaterally in levels IV and Vb. The ultrasonography demonstrated multiple lymph nodes with the snowstorm sign and a core biopsy confirmed a silicone granuloma (siliconoma). Read More

Int J Implant Dent 2021 Mar 2;7(1):16. Epub 2021 Mar 2.

Tokyo Medical and Dental University Dental Hospital, Tokyo Medical and Dental University, Tokyo, Japan.

Background: During implant treatment in the maxillary molar area, maxillary sinus floor augmentation is often performed to ameliorate the reduced alveolar bone height attributable to bone remodeling and pneumatization-induced expansion of the maxillary sinus. However, this augmentation may cause complications such as misplaced implants, artery damage, and maxillary sinus mucosal perforation; infections like maxillary sinusitis; and postsurgical complications such as bone graft leakage and postoperative nasal hemorrhaging. To reduce the complications during maxillary sinus floor augmentation and postoperative infections, we performed retrospective investigations of various systemic and local factors that influence pre-operative sinus mucosal thickness (SMT) by using cone-beam computed tomography (CBCT). Read More

Sci Rep 2021 Feb 24;11(1):4440. Epub 2021 Feb 24.

North End Medical Centre, London, UK.

Dental implant surgery on atrophied maxilla has many risks; in some patients, simultaneous sinus lifting with implant placement must be performed to increase the chances of successful implantation; this procedure can cause implant migration. Eleven patients were diagnosed with implant migration into the maxillary sinus in four anatomical areas: the sinus floor above the alveolar bone, near the junction of the sinus and nasal floor, near the floor of the orbit, and the most posterior aspect of the sinus. Surgical removal was performed through four different direct non-endoscopic transoral approaches depending on the location of the displaced implant. Read More

Exp Ther Med 2021 Mar 25;21(3):262. Epub 2021 Jan 25.

Department of Otorhinolaryngology, Head and Neck Surgery, Faculty of Medicine, Carl Gustav Carus, Technische Universität Dresden, D-01307 Dresden, Germany.

The etiology of hearing loss originates from genetic factors and includes several other events including infections, working or living environment, as well as several endocrine and metabolic disorders. The Vibrant Soundbridge (VSB) is an implantable hearing aid whose floating mass transducer (FMT) is attached to the long process of the incus. The device is used for pure sensorineural hearing loss with an intact middle ear. Read More

Int J Oral Maxillofac Implants 2021 Jan-Feb;36(1):154-164

Purpose: Using panoramic radiograph and CBCT to compare the measurement errors of the residual bone height in the same site before implant placement in the posterior maxilla and endo-sinus bone gain after osteotome sinus floor elevation without grafting, and to evaluate endo-sinus bone augmentation before stage-two surgery with CBCT. Also, some related factors of new bone formation in the sinus were analyzed, such as small bone block elevated by osteotome at the implant apex intraoperatively.

Materials And Methods: Patients were enrolled in the retrospective study; dental implants were placed in the maxillary posterior region using osteotome sinus floor elevation without grafting. Read More

Int J Oral Maxillofac Implants 2021 Jan-Feb;36(1):137-145

Purpose: To evaluate the clinical and radiographic outcomes of endoscope-assisted maxillary sinus floor elevation with platelet-rich fibrin grafting and simultaneous implant placement (PESS) in atrophic maxillae.

Materials And Methods: Twenty-three implants were placed to rehabilitate atrophic maxillae. Patient satisfaction was measured with a visual analog scale (VAS). Read More

Int J Oral Maxillofac Implants 2021 Jan-Feb;36(1):126-130

Purpose: To present a case series treated by inferior meatal antrostomy as a prophylactic maneuver after the placement of zygomatic implants to decrease the risk of sinusitis.

Materials And Methods: All patients undergoing zygomatic implant placement using the lower meatal antrostomy protocol between June 2011 and March 2019 at the Department of Oral and Maxillofacial Surgery, Universidad El Bosque, were included. Patients were evaluated after 12 months of the procedure using clinical and radiologic criteria described by Kuriyama and Reiskin. Read More

Clin Implant Dent Relat Res 2021 Feb 17;23(1):31-42. Epub 2021 Feb 17.

Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Cairo University, Cairo, Egypt.

Background: The overlying maxillary sinus frequently restrains the height of the posterior maxillary bones.

Purpose: Evaluating the effect of downsizing the antrostomy side-window on the stability of the installed implants and vertical bone gain, after employing a graftless antral membrane balloon elevation (AMBE).

Materials And Methods: The study is a randomized controlled clinical trial conducted on 20 patients with 30 deficient maxillary alveolar ridges underwent graftless (AMBE) after being allocated into a (5 mm) entry antrostomy group (the test group) and a (10 mm) entry antrostomy group (the control group) implementing a radiographic linear bone height and implant stability quotations (ISQ) comparison among both groups immediately after the placement of 38 Implants and 6 months after. Read More

J Craniomaxillofac Surg 2021 Feb 5. Epub 2021 Feb 5.

Unit of Maxillo-Facial Surgery and Dentistry, University of Verona, P.le L.A. Scuro 10, 37134, Verona, Italy.

This retrospective study assessed zygoma implants in patients treated for upper maxilla extreme atrophy, trauma, cleft palate, or failed reconstruction. The implants were placed using Quad (4 zygoma implants) or mixed (zygoma and conventional implants in premaxilla) surgical technique, with intra-sinus or extra-sinus approach, followed by immediate or deferred loading. Clinical and radiographic evaluations were carried out at 5-year follow-up from loading. Read More

Oral Surg Oral Med Oral Pathol Oral Radiol 2021 Jan 9:4547. Epub 2021 Jan 9.

Department of Oral and Maxillofacial Diseases, Helsinki University Hospital, Helsinki, Finland.

Objectives: Oral health and balanced occlusion are important aspects of a well-functioning face transplant. This study describes the oral and dental status, dental management, and sialoendoscopy of the first 2 patients in Helsinki who underwent face transplantations.

Study Design: Two patients received near-full face transplantations in 2016 and 2018, respectively. Read More

Facial Plast Surg 2021 Feb 8;37(1):92-97. Epub 2021 Feb 8.

Department of Otorhinolaryngology-Head and Neck Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

Objective:  Reconstruction of a weakened septal cartilage is a key procedure for the correction of deformed noses. However, when septal mucoperichondrium dissection is technically challenging, reconstruction of the lower two-thirds of the nose should be performed bypassing the damaged septal cartilage and mucosa. This article summarizes our experience with treating patients with severely damaged septal cartilage with bypass L-strut graft using costal cartilage. Read More

Shanghai Kou Qiang Yi Xue 2020 Oct;29(5):539-543

Department of Stomatology, Zhangye People's Hospital Affiliated to Gansu Hexi University. Zhangye 734000, Gansu Province, China.

Purpose: To investigate the long-term effects of residual bone height (RBH), maxillary sinus membrane perforation, and cavities on survival of implants with lateral maxillary sinus lifting (MSFA).

Methods: Fifty-six patients (98 implants) who underwent MSFA from 2005 to 2009 and followed up till 2019 were enrolled. RBH was assessed using a series of panoramic and periapical X-ray films. Read More

Am J Orthod Dentofacial Orthop 2021 Apr 1;159(4):e301-e310. Epub 2021 Feb 1.

Department of Orthodontics, School and Hospital of Stomatology, Shandong University, Shandong Key Laboratory of Oral Tissue Regeneration, and Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration, Jinan, Shandong, China. Electronic address:

Introduction: The objective of this research was to observe changes in aerodynamics and anatomic characteristics of the upper airway after mini-implants assisted rapid maxillary expansion and to evaluate the correlation between the 2 changes of the upper airway in young adults.

Methods: Thirty consecutive patients (mean age, 23.82 ± 3. Read More

J Biol Regul Homeost Agents 2020 Nov-Dec;34(6 Suppl. 2):89-100

Section of Oral and Maxillofacial Surgery, Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, Italy.

The rehabilitation of maxillary bone atrophy represents one of the main challenges of modern oral implantology. The use of zygomatic implants in the prosthetic rehabilitation of the patient affected by severe maxillary bone atrophy is another therapeutic alternative, not exempt from complications. The present study included 19 patients with edentulous maxillae who were treated between 2013 to 2015 with at least two zygomatic implants at the Department of Maxillofacial Surgery, Verona, Italy. Read More

J Biol Regul Homeost Agents 2020 Nov-Dec;34(6 Suppl. 2):9-20

Free practitioner in Padua, Italy.

The atrophic posterior ridges are usually characterized by poor bone quality and quantity: this situation requires the use of bone regenerative techniques. Other alternative surgical approaches are investigated. Nowadays the use of trans-sinus implants offers some advantages due to its feasibility. Read More