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Oral Oncol 2022 Jun 21;132:105980. Epub 2022 Jun 21.

Department of Oromaxillofacial-Head and Neck Surgery, Tianjin Stomatological Hospital, 75 Dagu Road, Heping District, Tianjin 300041, PR China; Tianjin Key Laboratory of Oral and Maxillofacial Function Reconstruction, 75 Dagu Road, Heping District, Tianjin 300041, PR China. Electronic address:

Objectives: The purpose of this retrospective study was to compare the differences in quality of life (QOL) outcomes between the conventional obturator prostheses (COP) and the pedicled submental artery island flap (SAIF) in the reconstruction of Brown IIb maxillary defects.

Materials And Methods: The QOL of 116 eligible patients who had a lapse ≥ 12 months after the cancer-related maxilla ablation was evaluated by the University of Washington quality of life scale (UW-QOL), Performance Status Scale for Head and Neck (PSS-HN), and Obturator Functioning Scale (OFS).

Results: Patients in the SAIF group reported statistically and clinically significant higher overall QOL scores but lower chewing scores in the UW-QOL scale when compared with those in the COP group (P < 0. Read More

Ann Med Surg (Lond) 2022 Jun 20;78:103837. Epub 2022 May 20.

Maxillofacial Surgery Department, Aleppo University Hospital, Aleppo, Syria.

Introduction: Facial injuries and deformities have received special attention during the previous decades for their functional, esthetic impairment, surgical challenges related to the location of the intervention, and their relationship to a lower survival rate. Moreover, there have been many surgical reconstructive methods due to the different materials and tools available and thus the final results following the surgical intervention.

Case Presentation: This study was conducted on two patients with severe war injuries; they both suffered from a significant loss in one or more of the following bones: the zygomatic bone, maxilla, nasal bone, infraorbital rim, and mandible. Read More

Med Pharm Rep 2022 Apr 28;95(2):214-217. Epub 2022 Apr 28.

Department of ENT, Faculty of Medical Sciences, Lebanese University.

Accidental implant displacement into the maxillary sinuses and accompanying complications are well documented in the literature. Two surgical approaches have been suggested to remove the displaced implants and to handle the related complications: an intraoral approach and the nasal endoscopy. The intraoral approach is preferred in cases of absence of local infection, ostium obstruction, and oroantral communication needing to be closed. Read More

Vaccine 2022 Jun 16. Epub 2022 Jun 16.

Immunisation Service, Department of Infectious Diseases, Perth Children's Hospital, Western Australia, Australia; Wesfarmers Centre for Vaccines and Infectious Diseases, Telethon Kids Institute, University of Western Australia, Western Australia, Australia.

Children with cochlear implants are at increased risk of invasive pneumococcal disease, with national and international guidelines recommending additional pneumococcal vaccines for these children. This study aimed to examine the pneumococcal immunization status and rate of invasive pneumococcal disease in children with cochlear implants at a tertiary paediatric hospital over a 12-year period. Additionally, the impacts of vaccination reminders and a dedicated immunization clinic on pneumococcal vaccination rates were assessed. Read More

Clin Implant Dent Relat Res 2022 Jun 14. Epub 2022 Jun 14.

Department of Oral and Maxillofacial Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Objectives: To retrospectively assess the treatment outcomes of endosseous implants placed to retain craniofacial prostheses.

Material And Methods: Patients with craniofacial defects resulting from congenital disease, trauma, or oncologic treatment had implant retained prostheses placed in the mastoid, orbital, or nasal region and then assessed over a period of up to 30 years. Implant survival rates were calculated with the Kaplan-Meier method. Read More

Dent Res J (Isfahan) 2022 27;19:38. Epub 2022 Apr 27.

Dental Implants Research Center, Dental Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.

Crouzon syndrome is an autosomal dominant trait, leading to midface deficiency, undeveloped orbits, short nasal dorsum, and exophthalmos as the typical clinical features. Early correction of craniofacial problems can improve patients' quality of life, but many of these patients with Crouzon syndrome are seeking treatment in older ages when they are missed for multidisciplinary management and distraction technique in proper timing. Modified LeFort III osteotomy is one of the treatment options that can be used for proper resolution in adult patients. Read More

Audiol Res 2022 Apr 21;12(3):212-223. Epub 2022 Apr 21.

Unit of Audiology, Regional Centre of Cochlear Implants and ENT Diseases, Department of Experimental and Clinical Medicine, Magna Graecia University, 88100 Catanzaro, Italy.

The SARS-CoV-2 vaccination campaign is probably one of the most historic public hygiene measures in modern medicine. The drama of the pandemic has forced the scientific community to accelerate the development and commercialization of vaccines, thereby enhancing the phases of active surveillance. Among the adverse events following immunization (AEFI) reported, those of an audiovestibular interest, such as sudden sensorineural hearing loss (SSNHL), tinnitus, dizziness, and vertigo, constitute a very small percentage. Read More

ACS Appl Mater Interfaces 2022 May 31. Epub 2022 May 31.

Department of Anatomy, National and Regional Engineering Laboratory of Tissue Engineering, State and Local Joint Engineering Laboratory for Vascular Implants, Key Lab for Biomechanics and Tissue Engineering of Chongqing, Third Military Medical University, Chongqing 400038, China.

Airborne pathogens, such as the world-spreading severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), cause global epidemics via transmission through the respiratory pathway. It is of great urgency to develop adequate interventions that can protect individuals against future pandemics. This study presents a nasal spray that forms a polysaccharide "armor" on the cell surface through the layer-by-layer self-assembly (LBL) method to minimize the risk of virus infection. Read More

Ear Nose Throat J 2022 May 28:1455613221106205. Epub 2022 May 28.

Department of Otorhinolaryngology-Head and Neck Surgery, 65722Chonnam National University Medical School and Hwasun Hospital, Hwasun, South Korea.

Antrochoanal polyp is usually a benign solitary mass lesion originated from maxillary sinus mucosa and emerging through maxillary ostium. We report a rare case of antrochoanal polyp and migrated dental implant in the ipsilateral maxillary sinus. Clinicians should be aware that ACP may have other concomitant conditions such as migrated dental implants. Read More

Ear Nose Throat J 2022 May 21:1455613221099483. Epub 2022 May 21.

Department of Otolaryngology-Head and Neck Surgery, College of Medicine, 191082King Saud University, Riyadh, Saudi Arabia.

Background: Recently, endoscopic endonasal approaches (EEA) have been used for skull base defect reconstruction surgeries. The nasoseptal flap (NSF), a vascular pedicled flap, was introduced to decrease postoperative cerebrospinal fluid (CSF) leakage.

Purposes: This study aimed to outline the authors' institutional experience using NSF and rigid implants in anterior skull base defect reconstruction surgeries following EEA. Read More

Facial Plast Surg 2022 May 11. Epub 2022 May 11.

Otolaryngology, Baylor College of Medicine, Houston, United States.

Nasal valve insufficiency can be addressed using endonasal and open structure surgical techniques. However, some patients may prefer or be better suited for minimally invasive techniques that allow for more expedient treatment in the clinical setting. Techniques include internal dilators, external dilators, suture suspension, lateral wall implants, and radiofrequency remodeling. Read More

J Prosthodont 2022 May 11. Epub 2022 May 11.

Pi Dental Center (Prosthodontics Intermedica, LLC), Institute for Facial Esthetics, Fort Washington, PA, USA.

This clinical report focuses on the challenges and solutions for a child subjected to craniofacial trauma from a wild hyena biting off his nose and anterior maxilla. Unique considerations in prosthodontics and biomedical engineering were required based on future craniofacial growth and development of the child. The physical requirement of a maximum retentive prosthesis for an active, athletic child required unique engineering designs and executions. Read More

Ear Nose Throat J 2022 May 2:1455613221099996. Epub 2022 May 2.

ENT Unit, 432601Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia.

Objectives: This study aimed to investigate the audiological outcomes and subjective benefits of transcutaneous bone conduction implants (BCIs) in patients with single-sided deafness (SSD).

Methods: This retrospective study was conducted on 11 patients with SSD implantations between 2015 and 2018 at a tertiary center. Pure-tone audiometry, speech reception threshold (SRT), and speech-in-noise (SPIN) tests were performed. Read More

Int J Oral Maxillofac Implants 2022 Mar-Apr;37(2):365-372

Purpose: The aim of this case-control study was to investigate the occurrence of bleeding events related to maxillary sinus elevation with a lateral window in patients under direct oral anticogulant therapy.

Materials And Methods: Seventyseven consecutive patients were scheduled for unilateral maxillary sinus floor elevation using a lateral window approach. Participants were divided into two groups: group A, formed by 37 patients who were under novel oral anticoagulation therapy (rivaroxaban/apixaban), and a control group, composed of 40 healthy subjects. Read More

J Dent 2022 Jun 21;121:104137. Epub 2022 Apr 21.

Department of Neurosciences, Unit of Dentistry, University of Padua, Italy.

Objectives: In the posterior maxilla, due to the presence of maxillary sinus, residual bone height lower than 3mm is a critical factor that can affect implant stability and survival. The use of guided surgery may facilitate the surgical procedures and the implant insertion in case of severely resorbed maxillae. Moreover, it may have beneficial effects on the long-term survival and success of implant-supported restorations. Read More

Maxillofac Plast Reconstr Surg 2022 Apr 22;44(1):17. Epub 2022 Apr 22.

Maxillofacial Surgery & Implantology & Biomaterial Research Foundation, Tehran, Iran.

Background: Various techniques with different grafts and implants have been proposed to establish a smooth and symmetric nasal dorsum with adequate function. Broadly, two categories of materials have been used in this regard: alloplastic implant materials and autograft materials. The aim of these meta-analyses is to explore the incidence of complications after dorsum augmentation surgery using alloplastic materials. Read More

Beijing Da Xue Xue Bao Yi Xue Ban 2022 Apr;54(2):356-362

Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China.

Objective: To evaluate the effect and summarize the characteristics of different treatment methods in repairing zygomatic defect.

Methods: A total of 37 patients with zygomatic defect were reviewed in the Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology from August 2012 to August 2019. According to the anatomical scope of defect, the zygomatic defects were divided into four categories: Class 0, the defect did not involve changes in zygomatic structure or continuity, only deficiency in thickness or projection; Class Ⅰ, defect was located in the zygomatic body or involved only one process; Class Ⅱ, a single defect involved two processes; Class Ⅲa, referred to a single defect involving three processes and above; Class Ⅲb, referred to zygomatic defects associated with large maxillary defects. Read More

J Clin Med 2022 Mar 28;11(7). Epub 2022 Mar 28.

Unité Fonctionnelle Implants Auditifs, Département d'Oto-Rhino-Laryngologie, Groupe Hospitalo-Universitaire Pitié-Salpêtrière, APHP Sorbonne Université, 75013 Paris, France.

Cochlear implantation is usually not recommended for prelingual profoundly deaf adults, although some of these patients might benefit from it. This study aims to define the candidates for cochlear implantation in this population. This retrospective study reviewed 34 prelingual profoundly deaf patients who had received a cochlear implant at 32 ± 1. Read More

Imaging Sci Dent 2022 Mar 13;52(1):11-18. Epub 2022 Jan 13.

Department of Radiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.

Purpose: This study aimed to assess incidental abnormal findings in the paranasal sinuses and anatomical variations of the ostiomeatal complex (OMC) on magnetic resonance imaging (MRI) scans.

Materials And Methods: MRI scans of 616 patients (mean age, 44.0±19. Read More

Front Allergy 2021 15;2:732909. Epub 2021 Dec 15.

Campania Regional Centre for Pharmacovigilance and Pharmacoepidemiology, Naples, Italy.

Innovation refers to the introduction of a product, a process, a service or a solution resulting in something new or significantly improved compared to the already available alternatives. In the clinical context, it is strictly related to the identification of a new added value in terms of quality, therapeutic efficacy and safety. Over the years several innovative approaches have been introduced in the clinical practice, revolutionizing the treatment and the management of important rhinologic conditions. Read More

Cornea 2022 May;41(5):635-639

Ocular Surface Advanced Center (CASO).

Purpose: The purpose of this study was to evaluate the feasibility of treating aniridia-associated keratopathy with a nonpenetrating artificial cornea in 2 patients with corneal blindness secondary to aniridia.

Methods: This was a prospective, nonrandomized, interventional study of 2 consecutive patients with corneal blindness caused by aniridia. Ophthalmological examination was performed before the nonpenetrating keratoprosthesis surgery and then repeated 1, 7, 15, 30, 90, and 180 days and subsequently every 90 days thereafter. Read More

J Control Release 2022 05 1;345:798-810. Epub 2022 Apr 1.

Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management, SVKMs NMIMS, V.L.Mehta Road, Vile Parle (W), Mumbai, Maharashtra 400056, India. Electronic address:

Family planning enables society to prevent unintended pregnancies and helps in attaining desired spacing between the pregnancies. It is done with the use of contraceptive methods and infertility treatments. The use of contraceptives serves to ease maternal ill-health and reduce pregnancy-related deaths and helps to decrease the number of unsafe abortions and HIV transmission from mothers to newborns. Read More

J Long Term Eff Med Implants 2022 ;32(1):7-18

A.B. Shetty Memorial Institute of Dental Sciences, Mangalore, India.

Introduction: Mini-implant assisted rapid palatal expansion (MARPE) is gradually becoming the treatment of choice to correct the transverse dimension, exceeding the limitations of conventional RME devices. One of the key factors for orthodontic diagnosis and treatment planning apart from a stable occlusion is a balanced and aesthetic facial profile that is influenced by maxillary expansion. Similarly, it also affects the anatomy and physiology of the nasal cavity since nasal airflow is a continuous stimulus for lowering of the palate and for lateral maxillary growth. Read More

Int J Implant Dent 2022 Apr 1;8(1):13. Epub 2022 Apr 1.

Department for Oral and Maxillofacial Surgery, Plastic Surgery, University Medical Center of the J. Gutenberg University Mainz, Augustusplatz 2, 55131, Mainz, Germany.

Introduction: There are few zygomatic implants (ZI) designs available. The objective of this non-interventional study was to report the effectiveness of two new site-specific ZI, selected and placed following the zygoma anatomy-guided approach (ZAGA).

Materials And Methods: Consecutive patients presenting indications for rehabilitation using ZI were treated according to ZAGA Concept recommendations. Read More

Orv Hetil 2022 03 27;163(13):527-531. Epub 2022 Mar 27.

1 Észak-Közép-budai Centrum, Új Szent János Kórház és Szakrendelő, Fül-Orr-Gége és Szájsebészeti Osztály, Semmelweis Egyetem, Általános Orvostudományi Kar, Oktató Osztály Budapest, Diós árok 1-3., 1125 Magyarország.

Összefoglaló. Az utóbbi időben egyre gyakoribbá vált fogászati implantáció egyik nem kívánt szövődménye az arcüregbe került implantátum, amely a maxilla molaris, esetenként praemolaris régiójának implantációjakor fordulhat elő. Ennek oka lehet a kúpsugaras komputertomográfia nélküli, azaz nem megfelelő tervezés, fennálló arcüreggyulladás és -ventilációs probléma, kevés, puha csont, a fúrási vagy implantátumbehelyezési sebészi gyakorlat hiánya, észre nem vett membránperforáció arcüreg-csontfeltöltés esetén. Read More

Int J Oral Maxillofac Implants 2022 March/April;37(2):407–415. Epub 2022 Mar 24.

Purpose: This study aimed primarily to examine the relationship between maxillary sinus variations and dental implant placement in the atrophic maxillary premolar-molar region. Secondly, the preferences of experienced clinicians with regard to implant length in the bone and sinus were evaluated.

Materials And Methods: The data were collected from panoramic radiographs of patients who had undergone dental implant surgery in the posterior maxilla. Read More

J Oral Sci 2022 Apr 24;64(2):129-134. Epub 2022 Mar 24.

Oral Hygiene Department, Maló Clinic.

Purpose: To evaluate the immediate function of anterior maxillary implants.

Methods: One hundred nine patients (42 males and 67 females; average age 55.2 years; range 38-81 years) were followed for 10 years. Read More

J Cataract Refract Surg 2022 05;48(5):634-636

From the Cincinnati Eye Institute, Cincinnati, Ohio (Amaral, Snyder); Hospital da Visao de Pernambuco, Recife, Brazil (Amaral); University of Cincinnai School of Medicine, Cincinnati, Ohio (Snyder).

In-the-bag placement is the ideal location for an anterior segment implant, including the custom flexible artificial iris prosthesis (CUSTOMFLEX ARTIFICIALIRIS). Yet, an injection of a bag-filling iris device through a reasonably sized capsulorhexis creates a geometric challenge. First, the device must be placed into an injection cartridge. Read More

Eur Arch Otorhinolaryngol 2022 Mar 16. Epub 2022 Mar 16.

Department of Oto-Rhino-Laryngology and Head-Neck Surgery, University of Szeged, Szeged, Hungary.

Purpose: Continuous technological advances result in the availability of new bone conduction hearing implants, of which their suitability for pediatric patients is of major concern. The CochlearOsia 2 is a new active osseointegrated steady-state implant system that uses digital piezoelectric stimulation to treat hearing loss. The implant in the United States was approved for patients aged 12 years and above, whereas the CE mark is independent of age, the only requirement is body weight of at least 7 kg. Read More

Minerva Dent Oral Sci 2022 02;71(1):25-30

Department of Dental Therapy, Faculty of Dental Medicine, University of Medicine, Tirana, Albania.

Background: Over the years, numerous studies and advanced technologies about dental implants have been evolved from the traditional two-stage procedure to immediate loading. Implants located in the posterior maxillary region allow to achieve an appropriate prosthetic support. The aim of this work was to solve the atrophied posterior maxilla, through monophasic implants with flapless technique and intraoral electro-welding. Read More