231,725 results match your criteria Nasal Fracture Imagings


BENRALIZUMAB REDUCES EOSINOPHILS AND INFLAMMATORY MARKERS IN PATIENTS WITH SEVERE EOSINOPHILIC ASTHMA AND CHRONIC RHINOSINUSITIS WITH NASAL POLYPS: A PILOT REAL-LIFE STUDY.

Immunol Lett 2022 Jun 22. Epub 2022 Jun 22.

Department of Oral and Maxillo-Facial Sciences, Sapienza University of Rome, Rome, Italy.

Chronic rhinosinusitis with nasal polyps (CRSwNP) and Severe Eosinophilic Asthma (SEA) are both frequently sustained by eosinophilic inflammation and are probably the manifestation of a unique disease of upper and lower respiratory tract. We retrospectively observe 11 patients with severe CRSwNP and concomitant SEA under add-on therapy with benralizumab evaluating symptoms using Sino Nasal Outcome Test-22 (SNOT-22), Visual Analogue Scale (VAS), and Asthma Control Test (ACT) and Nasal polyp size by endoscopic and radiological score by Nasal Polyp Score (NPS) and Lund-Mackay Score (LMS). At 6 and 12 months, the expression of cationic eosinophil protein (ECP), Interleukin 17 (IL-17), Interferon gamma (INF-γ) and vascular endothelial growth factor (VEGF) was measured by nasal scraping to assess mucosal inflammation. Read More

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Extent of craniofacial fungal osteomyelitis in a ketoacidotic patient may predict optic nerve involvement: A case report.

Int J Surg Case Rep 2022 Jun 13;96:107299. Epub 2022 Jun 13.

Department of Head and Neck Surgery, Facial Plastic and Reconstructive Surgery, University of Texas Rio Grande Valley, United States of America.

Introduction: Mucormycosis is an opportunistic mycosis common in poorly-controlled insulin dependent diabetic patients particularly with ketoacidosis. Fungal osteomyelitis is a life-threatening condition affectation of the nose and paranasal sinuses within the orofacial region.

Presentation Of Case: We present a 63-year-old diabetic male patient with maxillary mucormycotic osteomyelitis threatening his better seeing eye and review the clinical symptoms, relevant imaging, and management. Read More

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Endoscopic endonasal retrieval of air gun pellet retained in the frontal sinus: A case report.

Int J Surg Case Rep 2022 Jun 6;96:107280. Epub 2022 Jun 6.

Department of Otolaryngology-Head and Neck Surgery, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.

Introduction And Importance: Foreign bodies in paranasal sinuses are rarely encountered and most commonly present in the maxillary sinus. Guidelines for managing paranasal sinus object removal are limited due to its rarity. However, there are three major management options: open surgery, endoscopic sinus surgery, and observation. Read More

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Characteristics and Results of Hospital Admission Caused by Influenza Virus Infections in Children under 5 Years Old.

J Trop Pediatr 2022 Jun;68(4)

Department of Pediatric Diseases, Tepecik Training and Research Hospital, University of Health Sciences, Izmir, Turkey.

Aims: The influenza virus is an infectious disease with acute respiratory tract infections, caused secondary bacterial infections and death. In this study, we aimed to determine which predictors were associated with the need for high-flow nasal cannula oxygen therapy (HFNC) and transition to intensive care for influenza virus and also to compare single viral pathogens with multiple ones.

Methods: Inpatients under the age of 5 with influenza virus-related respiratory tract infections between November 2015 and March 2019 were included in the study. Read More

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Efficacy of Cysteamine and Methimazole in Treating Melasma A Comparative Narrative Review.

J Cosmet Dermatol 2022 Jun 25. Epub 2022 Jun 25.

Clinical Research Development Center, Shahid Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Melasma is a chronic and acquired pigmentary condition that primarily affects women and undermines patient satisfaction and confidence. Melasma mostly affects females, accounting for 90% of all cases. It affects people of all races, particularly those with skin types IV and V who live in areas with lots of UV radiation. Read More

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Neurofilament light chain plasma levels are associated with area of brain damage in experimental cerebral malaria.

Sci Rep 2022 Jun 24;12(1):10726. Epub 2022 Jun 24.

Department of Neuroradiology, Heidelberg University Hospital, Heidelberg, Germany.

Neurofilament light chain (NfL), released during central nervous injury, has evolved as a powerful serum marker of disease severity in many neurological disorders, including infectious diseases. So far NfL has not been assessed in cerebral malaria in human or its rodent model experimental cerebral malaria (ECM), a disease that can lead to fatal brain edema or reversible brain edema. In this study we assessed if NfL serum levels can also grade disease severity in an ECM mouse model with reversible (n = 11) and irreversible edema (n = 10). Read More

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Development of LC-HRMS untargeted analysis methods for nasal epithelial lining fluid exposomics.

J Expo Sci Environ Epidemiol 2022 Jun 24. Epub 2022 Jun 24.

Center for Environmental Medicine, Asthma and Lung Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.

Background: The nasal mucosa, as a primary site of entry for inhaled substances, contains both inhaled xenobiotic and endogenous biomarkers. Nasal mucosa can be non-invasively sampled (nasal epithelial lining fluid "NELF") and analyzed for biological mediators. However, methods for untargeted analysis of compounds inhaled and/or retained in the nasal mucosa are needed. Read More

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[Clinical characteristics and vaccination status of SARS-CoV-2 Omicron variant infected children].

Zhonghua Er Ke Za Zhi 2022 Jun 15;60(7):671-675. Epub 2022 Jun 15.

Department of Infection,Tianjin Children's Hospital (Children's Hospital of Tianjin University) Machang Campus, Tianjin 300074, China.

To investigate the clinical characteristics and vaccination status of SARS-CoV-2 Omicron variant infected children. A total of 105 children infected with Omicron variant admitted to Tianjin Haihe Hospital (designated referral hospital for SARS-CoV-2 infection in Tianjin) from January 8, 2022 to February 3 were included for a retrospective study. The cases were divided into pneumonia group and non-pneumonia group according to chest imaging. Read More

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Lip Lift.

Authors:
Angela Sturm

Otolaryngol Clin North Am 2022 Jun 21. Epub 2022 Jun 21.

Private Practice; Department of Otolaryngology-Head and Neck Surgery, University of Texas Medical Branch, Galveston, TX, USA. Electronic address:

The perioral area can be an important feature to convey femininity, particularly when speaking and smiling. A feminine lip has a shorter distance between the nasal sill and the vermillion border, fullness of the vermillion, and a few millimeters of tooth show with the mouth slightly open. The keys to a good outcome are incision design that respects the natural anatomy, placing the tension of the lift deep to the dermis to take tension off of the skin incision, determining the appropriate amount of lift for the patient's anatomy, and not violating the orbicularis oris. Read More

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Characteristics of Children Who Deteriorate After Transport and Associated Preadmission Factors.

Air Med J 2022 Jul-Aug;41(4):380-384. Epub 2022 May 27.

Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL; Department of Pediatrics, Northwestern University Feinberg School Medicine, Chicago, IL.

Objective: The incidence of deterioration and associated characteristics are largely unknown for children transported for admission from referring emergency departments (EDs) to general inpatient units. This study describes this population and identifies associated preadmission characteristics.

Methods: This single-center cohort study included children ≤ 18 years old transferred from an ED and directly admitted to general inpatient units from 2016 to 2019. Read More

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Use of circulating tumour DNA in nasopharyngeal carcinoma to detect minimal residual disease.

BMJ Case Rep 2022 Jun 24;15(6). Epub 2022 Jun 24.

Hematology and Medical Oncology, Oakland University William Beaumont School of Medicine, Troy, Michigan, USA.

Circulating tumour DNA (ctDNA) is defined as short DNA sequences shed by tumour cells into the systemic circulation. A promising use of ctDNA includes the detection of minimal residual disease (MRD) and is currently being studied in multiple types of solid tumours. Literature for the use of individualised ctDNA in nasopharyngeal carcinoma (NPC) is not available, although circulating Epstein-Barr virus DNA level is validated as a prognostic factor. Read More

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Dendrobium nobile protects against ovalbumin-induced allergic rhinitis by regulating intestinal flora and suppressing lung inflammation.

Chin J Nat Med 2022 Jun;20(6):443-457

Institute of Otolaryngology, Institute of Hearing and Speech of Sun Yat-sen University, Sun Yat-sen Me-morial Hospital, Sun Yat-sen University, Guangzhou 510520, China. Electronic address:

Antibiotic exposure-induced dysbiosis of the intestinal flora increases the risk of developing allergic rhinitis. Hence, regulating the balance of intestinal flora may be useful for preventing and treating allergic rhinitis. However, the underlying mechanism is unclear. Read More

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Development of the Sepsis-Associated Adverse Outcomes in Pregnancy Score.

Am J Perinatol 2022 Jun 24. Epub 2022 Jun 24.

Obstetrics & Gynecology, Department of Obstetrics, Gynecology, and Reproductive Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, United States.

Objective: To develop and evaluate a scoring system-called Sepsis-Associated Adverse Outcomes in Pregnancy (SAAP) Score-to identify individuals with maternal infection that have composite maternal adverse outcomes (CMAO).

Study Design: Using ICD codes, we identified pregnant and postpartum (up to 6 weeks after birth) individuals admitted at our center with a primary diagnosis of infection. The primary outcome was CMAO, which included any of the following: maternal intensive care unit admission, surgical intervention, vasopressor use, acute respiratory distress syndrome, pulmonary edema, mechanical ventilation, high flow nasal cannula, disseminated intravascular coagulation, dialysis, organ failure, venous thromboembolism, or maternal death. Read More

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Viral infection and allergy status impact severity of asthma symptoms in children with asthma exacerbations.

Ann Allergy Asthma Immunol 2022 Jun 21. Epub 2022 Jun 21.

Department of Pediatrics, Division of Allergy and Immunology, University of Arkansas for Medical Sciences, Little Rock, AR; Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, AR; Arkansas Children's Research Institute, Little Rock, AR. Electronic address:

Background: While viral infection is known to be associated with asthma exacerbations, prior research has not identified reliable predictors of acute symptom severity in virus-related asthma exacerbations (VRAE).

Objective: To determine the effect of asthma control and viral infection on the severity of current illness and evaluate biomarkers related to acute symptoms during asthma exacerbations.

Methods: We prospectively enrolled 120 children with physician diagnosed asthma and current wheezing who presented to Arkansas Children's Hospital Emergency Department. Read More

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Nasal Transposition of the Split Lateral Rectus Muscle for Strabismus Associated with Bilateral 3-Nerve Palsy.

Am J Ophthalmol 2022 Jun 21. Epub 2022 Jun 21.

Departments of Ophthalmology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA. Electronic address:

Purpose: To determine success rate and complications associated with nasal transposition of the split lateral rectus muscle (NTSLR) for treating bilateral 3-nerve palsy.

Design: Retrospective, interventional case series METHODS: : Setting: International, multicenter registry Study population: All patients with bilateral 3-nerve palsy treated with NTSLR.

Observation: Sensorimotor evaluations before and 6-months after unilateral or bilateral NTSLR. Read More

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Histomorphological features of mucormycosis with rise and fall of COVID-19 pandemic.

Pathol Res Pract 2022 Jun 17;236:153981. Epub 2022 Jun 17.

Department of Pathology, PSG Institute of Medical Sciences and Research, Coimbatore, India. Electronic address:

Introduction: Due to Corona Virus disease -19, India saw a surge of mucormycosis cases, associated with high death rate. India, during the month of May to July 2021 saw a surge of mucormycosis from all states, with close to 50,000 cases just in a span of 3 months.

Objective: To examine the histopathological appearances of rhino-orbital/rhino-maxillary/sino-nasal mucormycosis in the backdrop of the ongoing COVID 19 pandemic. Read More

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Large Isolated Nasoorbital Type of Frontoethmoidal Encephalomeningocele: A Case Report With Long-Term Follow-up.

Ann Plast Surg 2022 Jul;89(1):49-53

From the Chiangmai Craniofacial Center, Division of Plastic and Reconstructive Surgery, Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

Abstract: Frontoethmoidal encephalomeningocele (FEEM) is a rare congenital craniofacial malformation with increased incidence in Southeast Asia, especially in Thailand. Because of its rarity, main treatment obstacles include the lack of surgical treatment techniques and long-term postoperative follow-up data. The authors present the case of a 9-month-old boy who was born with a large isolated nasoorbital type of FEEM, which had a pressure effect on his right eye, nose, and facial complex. Read More

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Quality of life in patients with cancer-related Brown IIb maxillary defect: A comparison between conventional obturation rehabilitation and submental flap reconstruction.

Oral Oncol 2022 Jun 21;132:105980. Epub 2022 Jun 21.

Department of Oromaxillofacial-Head and Neck Surgery, Tianjin Stomatological Hospital, 75 Dagu Road, Heping District, Tianjin 300041, PR China; Tianjin Key Laboratory of Oral and Maxillofacial Function Reconstruction, 75 Dagu Road, Heping District, Tianjin 300041, PR China. Electronic address:

Objectives: The purpose of this retrospective study was to compare the differences in quality of life (QOL) outcomes between the conventional obturator prostheses (COP) and the pedicled submental artery island flap (SAIF) in the reconstruction of Brown IIb maxillary defects.

Materials And Methods: The QOL of 116 eligible patients who had a lapse ≥ 12 months after the cancer-related maxilla ablation was evaluated by the University of Washington quality of life scale (UW-QOL), Performance Status Scale for Head and Neck (PSS-HN), and Obturator Functioning Scale (OFS).

Results: Patients in the SAIF group reported statistically and clinically significant higher overall QOL scores but lower chewing scores in the UW-QOL scale when compared with those in the COP group (P < 0. Read More

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Evaluation of effect of septoplasty on nasal mucosal dryness using intranasal Schirmer test.

Acta Otolaryngol 2022 Jun 24:1-4. Epub 2022 Jun 24.

Department of Otorhinolaryngology, Head and Neck Surgery, Ataturk University Faculty of Medicine, Erzurum, Turkey.

Background: Septal deviation causes the air entering the nose to encounter resistance and leads to turbulent flow formation by disrupting laminar air flow. In the literature, the Schirmer test has been recommended to evaluate the moistening of the nasal mucosa.

Aims/objectives: The purpose of this study was to evaluate the degree of nasal humidification using the intranasal schirmer test in patients with septal deviation and to reveal changes in mucosal dryness and humidity in both nasal cavities following septoplasty surgery. Read More

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Analysis of neutrophil functional activity in patients with chronic polyposis rhinosinusitis after treatment with interferon gamma.

Klin Lab Diagn 2022 Jun;67(6):339-344

Penza Institute for Further Training of Physicians - Branch Campus of the Federal State Budgetary Educational Institution of Further Professional Education «Russian Medical Academy of Continuing Professional Education» of the Ministry of Healthcare of the Russian Federation.

Chronic polyposis rhinosinusitis (CPRS) is an inflammatory disease of the nose and paranasal sinuses, accompanied by the formation and recurrent growth of polyps. PDRS is an urgent medical problem, because it is difficult to treat and is accompanied by constant exacerbations. The important role of neutrophil granulocytes in the pathogenesis of CPRS has been proved, as they are the first line of defense in response to tissue damage and active participants in the pathological process. Read More

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The Clinical and Genomic Epidemiology of Rhinovirus in Homeless Shelters-King County, Washington.

J Infect Dis 2022 Jun 24. Epub 2022 Jun 24.

Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle (98195), Washington, USA.

Background: Rhinovirus (RV) is a common cause of respiratory illness in all people, including those experiencing homelessness. RV epidemiology in homeless shelters is unknown.

Methods: We analyzed data from a cross-sectional homeless shelter study in King County, Washington, October 2019-May 2021. Read More

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There is chemistry in social chemistry.

Sci Adv 2022 Jun 24;8(25):eabn0154. Epub 2022 Jun 24.

The Azrieli National Institute for Human Brain Imaging and Research and Department of Brain Research, Weizmann Institute of Science, Rehovot, Israel.

Nonhuman terrestrial mammals sniff themselves and each other to decide who is friend or foe. Humans also sniff themselves and each other, but the function of this is unknown. Because humans seek friends who are similar to themselves, we hypothesized that humans may smell themselves and others to subconsciously estimate body odor similarity, which, in turn, may promote friendship. Read More

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Montgomery-Åsberg Depression Rating Scale factors in treatment-resistant depression at onset of treatment: Derivation, replication, and change over time during treatment with esketamine.

Int J Methods Psychiatr Res 2022 Jun 24:e1927. Epub 2022 Jun 24.

Clinical Medical Affairs, Janssen Scientific Affairs LLC, Titusville, New Jersey, USA.

Objective: Derive and confirm factor structure of the Montgomery-Åsberg Depression Rating Scale (MADRS) in patients with treatment-resistant depression (TRD) and evaluate how the factors evident at baseline change over 4 weeks of esketamine treatment.

Methods: Two similarly-designed, short-term TRANSFORM trials randomized adults to esketamine or matching placebo nasal spray, each with a newly-initiated oral antidepressant, for 4 weeks (TRANSFORM-1: N = 342 patients; TRANSFORM-2: N = 223 patients). The factor structure of MADRS item scores at baseline was determined by exploratory factor analysis in TRANSFORM-2 and corroborated by confirmatory factor analysis in TRANSFORM-1. Read More

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Ciliary Muscle Dimension Changes With Accommodation Vary in Myopia and Emmetropia.

Invest Ophthalmol Vis Sci 2022 Jun;63(6):24

Centre for Vision and Eye Research, Queensland University of Technology, Kelvin Grove, Queensland, Australia.

Purpose: The purpose of this study was to determine whether accommodation-induced changes in ciliary muscle dimensions vary between emmetropes and myopes, and the effect of the image analysis method.

Methods: Seventy adults aged 18 to 27 years consisted of 25 people with emmetropia (spherical equivalent refraction [SER] +0.21 ± 0. Read More

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Intranasal clotrimazole spray 1% associated with oral itraconazole for nasal feline sporotrichosis: a case series.

Rev Bras Med Vet 2022 26;44:e004821. Epub 2022 May 26.

Veterinarian, DSc. DMCV, IV, UFRRJ. Seropédica, RJ, Brazil.

Feline sporotrichosis is a major clinical problem among cats in Brazil and is also a neglected, but important, public health issue, due to its zoonotic potential. The nasal clinical form of the disease is particularly challenging, having treatment refractoriness and clinical signs relapse as common features. This case series study aimed to preliminarily describe the effects of the azolic antifungal drug, clotrimazole, as a topical 1% solution spray, together with itraconazole on inducing disease remission, as well as treatment tolerability and safety. Read More

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Deadbolt cataract due to misplanted minishunt.

Authors:

J Cataract Refract Surg 2022 Jul;48(7):863

A 62-year-old woman with stable unilateral glaucoma in the left eye presented for a cataract consultation. In 2010, laser peripheral iridotomies (LPI) were performed on both eyes by a different provider. Her postoperative course was complicated by a recalcitrant steroid response with a highest intraocular pressure (IOP) of 65 mm Hg in the left eye. Read More

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CT-Guided Thermocoagulation of the Pterygopalatine Ganglion for Refractory Trigeminal Autonomic Cephalalgia.

Pain Ther 2022 Jun 24. Epub 2022 Jun 24.

Department of Anesthesiology and Pain Medicine, The Affiliated Hospital of Jiaxing University, No. 1882 Zhong Huan South Road, Jiaxing, 314000, Zhejiang, China.

Introduction: Trigeminal autonomic cephalalgia (TAC) is a type of one-sided cerebral painful headache, with attacks regularly accompanied by autonomic responses, such as tearing, runny nose, panic, nausea and vomiting on the affected side. Currently, the most common treatment strategies are drugs, nerve grafts and surgery. Clinical understanding of TACs is limited. Read More

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Does Maras powder affect the nasal mucociliary clearence?

Eur Arch Otorhinolaryngol 2022 Jun 24. Epub 2022 Jun 24.

Faculty of Medicine, Department of Otolaryngology, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey.

Purpose: Many studies have been conducted about the effect of cigarettes and other tobacco products on mucociliary clearance. However, there has been no study of the relationship between mucociliary clearance and Maras powder, which is a smokeless tobacco product. The aim of this study was to evaluate the effect of Maras powder use on mucociliary clearance through comparisons with cigarette smokers and those who used no tobacco products. Read More

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Presurgical olfactory function as an indicator of the outcome of functional endoscopic sinus surgery in chronic rhinosinusitis with nasal polyps.

Eur Arch Otorhinolaryngol 2022 Jun 24. Epub 2022 Jun 24.

Smell and Taste Clinic, Department of Otorhinolaryngology, TU Dresden, Dresden, Germany.

Introduction: Chronic rhinosinusitis with nasal polyps (CRSwNP) often leads to impaired olfactory function and reduced quality of life. When conservative treatments such as nasal irrigation and topical steroids fail, functional endoscopic sinus surgery (FESS) is often necessary, because it improves symptoms and enhances quality of life.

Materials And Methods: A total of 88 patients was included in this prospective study. Read More

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X-shaped Tip Graft: A Versatile Solution for Warping Correction in Rib Cartilage Based Rhinoplasty.

Aesthet Surg J 2022 Jun 24. Epub 2022 Jun 24.

Department of Plastic Surgery, Chinese Academy of Medical Sciences & Peking Union Medical College, Plastic Surgery Hospital and Institute, Beijing, PR China.

Background: An enduringly stable tip graft is the key to achieve successful rhinoplasty case. However, the intrinsic nature of rib graft warping renders major unpredictability for the long-term outcome.

Objectives: The aim of this study was to detail and validate the utilization of a tip graft that is characterized by the circumferential split on the tip graft, which consequently renders a shape similar to the letter of X (Chi). Read More

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