207,337 results match your criteria Nasal Fracture Imagings


Spontaneous, Intrasphenoidal Rupture of Ecchordosis Physaliphora with Pneumocephalus Captured During Serial Imaging and Clinical Follow-up: Pathoanatomic Features and Management.

World Neurosurg 2020 May 31. Epub 2020 May 31.

Department of Radiology, NYU Langone Health, New York, New York. Electronic address:

Background: Ecchordosis physaliphora (EP) is a congenital, uniformly asymptomatic, hamartomatous lesion of the primitive notochord. Herein we report, to our knowledge, the first credible case report of unprovoked intra-sphenoidal rupture resulting in recurrent pneumocephalus and cerebrospinal fluid (CSF) leak, definitively captured over serial imaging during clinical and radiologic surveillance.

Case Description: A 68-year old woman with Marfan syndrome presented to the Emergency Department with the worst headache of life. Read More

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http://dx.doi.org/10.1016/j.wneu.2020.05.220DOI Listing

Clinical Manifestations of Children with COVID-19: a Systematic Review.

Pediatr Pulmonol 2020 Jun 3. Epub 2020 Jun 3.

Pediatric Intensive Care Unit, Department of Pediatrics, State University of Campinas (UNICAMP), Campinas, SP, Brazil.

Background: The coronavirus disease 2019 (COVID-19) outbreak is an unprecedented global public health challenge, leading to thousands of deaths every day worldwide. Despite the epidemiological importance, clinical patterns of children with COVID-19 remain unclear. The aim of this study was to describe the clinical, laboratorial and radiological characteristics of children with COVID-19. Read More

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http://dx.doi.org/10.1002/ppul.24885DOI Listing

Facial profile changes due to bone cement graft to manage the hyperactive muscles of the gingival smile.

Dental Press J Orthod 2020 Mar 29;25(2):44-51. Epub 2020 May 29.

Divisão de Endodontia, Faculdade de Odontologia, Universidade Federal de Goiás, Goiânia, GO, Brazil.

Objective: To evaluate facial profile changes promoted by polymethyl methacrylate (PMMA) cement graft to reduce excessive gingival display due to hyperactivity of the elevator muscles of the upper lip during smiling.

Methods: Eleven patients (all females, age range: 20 to 43 years) presenting gingival smile that were treated with PMMA cement grafts in a private clinic were selected for this retrospective study. Three angular and ten linear cephalometric facial profile measurements were performed preoperatively (baseline, T1) and at least 6 months postoperatively (T2). Read More

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http://dx.doi.org/10.1590/2177-6709.25.2.044-051.oarDOI Listing

Intensive Care Unit Utilization After Adoption of a Ward-Based High-Flow Nasal Cannula Protocol.

J Hosp Med 2020 May 21. Epub 2020 May 21.

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

Background: Hospitals are increasingly adopting ward-based high-flow nasal cannula (HFNC) protocols that allow HFNC treatment of bronchiolitis outside of the intensive care unit (ICU). Our objective was to determine whether adoption of a ward-based HFNC protocol reduces ICU utilization.

Methods: We examined a retrospective cohort of infants aged 3 to 24 months hospitalized with bronchiolitis at hospitals in the Pediatric Health Information System database. Read More

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http://dx.doi.org/10.12788/jhm.3417DOI Listing

Vismodegib Experience in a Renal Transplant Patient With Basal Cell Carcinoma.

Exp Clin Transplant 2020 Jun 2. Epub 2020 Jun 2.

From the Medical Oncology Department and the 2Transplantation Department, Baskent University, Ankara, Turkey.

The hedgehog inhibitor vismodegib has been tested and suggested as an effective treatment option for cases of locally advanced or metastatic basal cell carcinoma. A 58-year-old female renal transplant patient with recurrent, inoperable basal-cell carcinoma that originated from nasal skin was evaluated by the transplantation counsel. After a multidisciplinary evaluation of the patient, vismodegib at a dose of 150 mg/day was started in February 2018. Read More

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http://dx.doi.org/10.6002/ect.2020.0293DOI Listing

Detecting head and neck squamous carcinoma using a portable handheld electronic nose.

Head Neck 2020 Jun 3. Epub 2020 Jun 3.

Department of Otorhinolaryngology, Head and Neck Surgery, Maastricht University Medical Center, Maastricht, The Netherlands.

Introduction: Detecting volatile organic compounds in exhaled breath enables the diagnosis of cancer. We investigated whether a handheld version of an electronic nose is able to discriminate between patients with head and neck squamous cell cancer (HNSCC) and healthy controls.

Methods: Ninety-one patients with HNSCC and 72 controls exhaled through an e-nose. Read More

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http://dx.doi.org/10.1002/hed.26293DOI Listing

A dental implant dislocated in the ethmoidal sinus: A case report.

Heliyon 2020 May 27;6(5):e03977. Epub 2020 May 27.

IRCCS Centro Neurolesi "Bonino Pulejo", Messina, Italy.

Maxillary sinusitis can represent a rare complication of dental implants of endodontic materials impinging in the maxillary sinuses. The effects of anatomical variants of paranasal sinuses on pathophysiological and clinical manifestations of dental sinusitis are poorly understood. Herein, we present a case of dislocation of a dental implant in the ethmoidal sinus in a 63-years old man with bilateral accessory maxillary orifice. Read More

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http://dx.doi.org/10.1016/j.heliyon.2020.e03977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260438PMC

Bilateral Double-headed Recurrent Pterygium: A Case Presentation and Literature Review.

Med Hypothesis Discov Innov Ophthalmol 2020 15;9(2):85-90. Epub 2020 Mar 15.

Department of Ophthalmology, Mustafa Kemal University Tayfur Ata Sokmen Faculty of Medicine, Hatay, Turkey.

Pterygium is a frequent corneal disease characterized by growing of fibrovascular tissue from the bulbar conjunctiva onto the cornea. Although the causes of pterygium are not obvious, sun exposure is closely correlated with its development. Pterygium, especially double-headed pterygium is mostly seen in warm climate and in individuals who work outdoors. Read More

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A novel quantitative real-time PCR diagnostic assay for fecal and nasal swab detection of an otariid lungworm, .

Int J Parasitol Parasites Wildl 2020 Aug 18;12:85-92. Epub 2020 May 18.

Smith College, Department of Biological Sciences, Northampton, MA, 01063, USA.

also known as sea lion lungworm, is a metastrongyloid nematode that infects otariid hosts, such as the charismatic California sea lion, causes bronchointerstitial pneumonia, respiratory distress, reduced ability to swim, dive and hunt and as a result, increased mortality particularly in young animals. Respiratory disease is a leading cause of stranding and admission to rehabilitation centers on the Pacific coast. Low-coverage genomic sequencing of four individuals analyzed through Galaxy's RepeatExplorer identified a novel repeat DNA family we employed to design a sensitive quantitative PCR (qPCR) assay for diagnosing infections from fecal or sputum samples. Read More

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http://dx.doi.org/10.1016/j.ijppaw.2020.04.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256429PMC

Morphometric analysis of nasopalatine foramen in Sri Lankan population using CBCT.

J Oral Biol Craniofac Res 2020 Apr-Jun;10(2):238-240. Epub 2019 Dec 3.

Department of Oral Medicine and Periodontology, Faculty of Dental Sciences, University of Peradeniya, Sri Lanka.

Nasopalatine canal (NPC) is an important anatomical structure present in the anterior mid maxilla. It has the synonyms of incisive canal or anterior palatine canal. The objective of this study was to identify the morphometric characteristics of the NPC in group of Sri Lankan people using Cone beam computer tomography (CBCT) and to determine normal morphological course and anatomical variations. Read More

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http://dx.doi.org/10.1016/j.jobcr.2019.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254471PMC
December 2019

Recurrent Ameloblastoma Involving Fibula Neo-mandible: Management with Digital Planning and Reconstruction Using a Contralateral Free Fibula Flap.

Cureus 2020 Apr 29;12(4):e7880. Epub 2020 Apr 29.

Maxillofacial Surgery, St. James's Hospital, Dublin, IRL.

Ameloblastoma is a locally aggressive tumor that most commonly arises in the mandible. It has a high rate of recurrence if inadequately excised. We report a case of a patient who developed recurrence of his ameloblastoma in his fibula flap mandibular reconstruction despite clear resection margins 23 years after resection. Read More

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http://dx.doi.org/10.7759/cureus.7880DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255542PMC

A 55-year-old COVID-19-positive man managed with self-regulation of high-flow oxygen by high-velocity nasal insufflation therapy.

Respirol Case Rep 2020 Jul 21;8(5):e00591. Epub 2020 May 21.

Mount Sinai Medical Center Miami Beach FL USA.

Management of critically ill coronavirus disease 2019 (COVID-19) patients remains both risky and technically challenging. A 55-year-old male COVID-19-positive patient with obstructive sleep apnoea (OSA), diabetes, and obesity presented with cough and shortness of breath, escalating to requiring high-flow oxygen therapy by high-velocity nasal insufflation. The patient's flow rate and oxygen fraction remained labile throughout much of the hospitalization. Read More

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http://dx.doi.org/10.1002/rcr2.591DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240337PMC

Recent trends in airway management.

F1000Res 2020 13;9. Epub 2020 May 13.

Department of General Anesthesiology, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.

Clinical airway management continues to advance at a fast pace. To help update busy anesthesiologists, this abbreviated review summarizes notable airway management advances over the past few years. We briefly discuss advances in video laryngoscopy, in flexible intubation scopes, in jet ventilation, and in extracorporeal membrane oxygenation (ECMO). Read More

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http://dx.doi.org/10.12688/f1000research.21914.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222034PMC

High-flow nasal cannula oxygen therapy as an emerging option for respiratory failure: the present and the future.

Ther Adv Chronic Dis 2020 13;11:2040622320920106. Epub 2020 May 13.

Dipartimento di Medicina Clinica e Sperimentale, University of Catania, Catania, Italy.

Conventional oxygen therapy (COT) and noninvasive ventilation (NIV) have been considered for decades as frontline treatment for acute or chronic respiratory failure. However, COT can be insufficient in severe hypoxaemia whereas NIV, although highly effective, is poorly tolerated by patients and its use requires a specific expertise. High-flow nasal cannula (HFNC) is an emerging technique, designed to provide oxygen at high flows with an optimal degree of heat and humidification, which is well tolerated and easy to use in all clinical settings. Read More

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http://dx.doi.org/10.1177/2040622320920106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238775PMC

Serum periostin levels in asthma patients in relation to omalizumab therapy and presence of chronic rhinosinusitis with nasal polyps.

Postepy Dermatol Alergol 2020 Apr 6;37(2):240-249. Epub 2020 May 6.

Institute of Clinical Immunology and Allergy, University Hospital in Hradec Králové, Faculty of Medicine, Charles University in Prague, Czech Republic.

Introduction: The serum periostin level is a promising biomarker of type 2- high inflammation pattern of bronchial asthma. It has been proven that serum periostin levels decrease in response to systemic and inhaled corticosteroid (ICS) therapy. However, we have only limited knowledge about changes in serum periostin levels reflecting omalizumab (OMA) treatment and other variables, such as chronic rhinosinusitis with nasal polyps (CRSwNP). Read More

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http://dx.doi.org/10.5114/ada.2020.94842DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262810PMC

carriage state in healthy adult population and phenotypic and genotypic properties of isolated strains.

Postepy Dermatol Alergol 2020 Apr 5;37(2):184-189. Epub 2020 May 5.

Laboratory of Environmental and Occupational Hazards, University of Life Sciences, Lublin, Poland.

Introduction: At present, infections induced by staphylococci, especially methicillin-resistant (MRSA) are one of key therapeutic and epidemiological problems.

Aim: The assessment of carrier state occurrence among a healthy adult population as well as determination of phenotypic and genotypic properties of the isolated strains.

Material And Methods: The study included 100 healthy individuals. Read More

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http://dx.doi.org/10.5114/ada.2020.94837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262795PMC

Isolation of ultrasmall (filterable) bacteria from patients suffering from ME, and patients and staff of a paediatric hospital.

Saudi J Biol Sci 2020 Jun 13;27(6):1566-1568. Epub 2020 Mar 13.

Department of Botany and Microbiology, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.

A total of 108 blood samples obtained from 28 male and 80 female patients diagnosed with ME were diluted in sterile, Ringer's Solution and forced (by suction) through 0.2 µm filters. Of the 28 male samples, 4 yielded filterable bacteria and of the 80 female samples, 18 gave filterable bacteria; as a result, of the total of 124 samples, 22 yielded FB. Read More

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http://dx.doi.org/10.1016/j.sjbs.2020.03.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253900PMC

[Recent advances in treatment of viral pneumonia using Chinese patent medicine].

Zhongguo Zhong Yao Za Zhi 2020 Apr;45(7):1509-1514

Tianjin University of Traditional Chinese Medicine Tianjin 301617, China.

Viral pneumonia is caused by a spreading of lung infection caused by respiratory viruses. Some virus infections were found to be highly aggressive, leading to lung inflammation and severe damage in respiratory system with high fatality rate. Currently, there is no effective therapeutic drugs in the clinic. Read More

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http://dx.doi.org/10.19540/j.cnki.cjcmm.20200312.502DOI Listing

Trends and clinicopathological characteristics of oral squamous cell carcinomas reported at a tertiary cancer hospital in Nepal during 1999 to 2009.

Clin Exp Dent Res 2020 Jan 12. Epub 2020 Jan 12.

Department of Oral Biology, Faculty of Dentistry, University of Oslo, Oslo, Norway.

Objective: Reliable data describing the trends and clinicopathological characteristics of oral squamous cell carcinoma (OSCC) in the Nepalese population are very limited. The current study aimed to examine the demographics, trend, and clinicopathological characteristics of OSCC reported to the main referral/tertiary cancer hospital, the B.P. Read More

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http://dx.doi.org/10.1002/cre2.278DOI Listing
January 2020

Signet Ring Cell Differentiation in Salivary Duct Carcinoma with Rhabdoid Features: Report of Three Cases and Literature Review.

Head Neck Pathol 2020 Jun 2. Epub 2020 Jun 2.

Section of Oncopathology and Regenerative Biology, Department of Pathology, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan.

Salivary duct carcinoma with rhabdoid features (SDCRF) is a rare salivary tumor with poor prognosis and is proposed as a salivary counterpart of pleomorphic lobular carcinoma of the breast (PLCB). Here, we report three cases of SDC with rhabdoid features (SDCRF) mimicking PLCB. Pleomorphic adenoma (PA) component was accompanied in all the cases confirming carcinoma ex PA. Read More

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http://dx.doi.org/10.1007/s12105-020-01186-4DOI Listing

Can ocular changes be detected early in children and adolescents with type 1 diabetes mellitus without retinopathy by using optical biometry and optical coherence tomography?

Int Ophthalmol 2020 Jun 1. Epub 2020 Jun 1.

Faculty of Medicine, Department of Pediatric Endocrinology, Izmir Katip Celebi University, Izmir, Turkey.

Purpose: To determine early ocular changes in children and adolescents with type 1 diabetes mellitus without retinopathy (T1DM-woR) by optical biometry (OB) and optical coherence tomography (OCT).

Methods: Seventy children and adolescents with T1DM-woR (patient group) and 72 healthy children and adolescents (control group) were included. Demographic data, anthropometric measurements and anterior-posterior segment parameters of groups were compared. Read More

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http://dx.doi.org/10.1007/s10792-020-01430-4DOI Listing

Fur Seal Feces-Associated Circular DNA Virus Identified in Pigs in Anhui, China.

Virol Sin 2020 Jun 2. Epub 2020 Jun 2.

State Key Laboratory of Veterinary Biotechnology and State Data Center for Animal Infectious Diseases, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, 150000, China.

Fur seal feces-associated circular DNA virus (FSfaCV) is an unclassified circular replication-associated protein (Rep)-encoding single-stranded (CRESS) DNA virus that has been detected in mammals (fur seals and pigs). The biology and epidemiology of the virus remain largely unknown. To investigate the virus diversity among pigs in Anhui Province, China, we pooled 600 nasal samples in 2017 and detected viruses using viral metagenomic methods. Read More

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http://dx.doi.org/10.1007/s12250-020-00232-3DOI Listing

Voice outcomes for patients undergoing surgery for obstructive sleep apnea: a systematic review and meta-analysis.

Eur Arch Otorhinolaryngol 2020 Jun 2. Epub 2020 Jun 2.

Department of Otolaryngology, Head and Neck Surgery, Gulhane Medical School, Ankara, Turkey.

Purpose: To evaluate the effect of the different surgical techniques used in the treatment of obstructive sleep apnea (OSA) on the postoperative voice and nasalance, and to conduct a meta-analysis through the assessment of postoperative changes.

Methods: Systematic literature review and meta-analysis of published data using the data sources, MEDLINE, Google Scholar, Cochrane, and SAGE. All studies published in English specifying any upper airway surgery for treatment of snoring and/or OSA were included, provided they indicated the pre- and postoperative mean ± standard deviation (SD) values for voice parameters and nasality. Read More

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http://dx.doi.org/10.1007/s00405-020-06101-9DOI Listing

Substitution of warthog NF-κB motifs into RELA of domestic pigs is not sufficient to confer resilience to African swine fever virus.

Sci Rep 2020 Jun 2;10(1):8951. Epub 2020 Jun 2.

Virology Department, Animal and Plant Health Agency, APHA-Weybridge, Woodham Lane, New Haw, Addlestone, KT15 3NB, UK.

African swine fever virus (ASFV) causes a lethal, haemorrhagic disease in domestic swine that threatens pig production across the globe. Unlike domestic pigs, warthogs, which are wildlife hosts of the virus, do not succumb to the lethal effects of infection. There are three amino acid differences between the sequence of the warthog and domestic pig RELA protein; a subunit of the NF-κB transcription factor that plays a key role in regulating the immune response to infections. Read More

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http://dx.doi.org/10.1038/s41598-020-65808-1DOI Listing

Association Between Structure-function Characteristics and Visual Field Outcomes in Glaucoma Subjects with Intraocular Pressure Reduction After Trabeculectomy.

J Glaucoma 2020 Jun 1. Epub 2020 Jun 1.

Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.

Precis: Improvements in post-trabeculectomy visual field outcomes were found to be significantly associated with pre-operative nerve fiber layer thickness parameters extracted from the sectorized structure-function relationship, baseline visual field and severity of glaucoma.

Objective: To determine whether the pre-operative structure-function relationship helps to predict visual outcomes at one-year post-trabeculectomy.

Patients And Methods: 91 eyes from 87 participants who successfully underwent trabeculectomy were included in our study. Read More

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http://dx.doi.org/10.1097/IJG.0000000000001550DOI Listing

Variations in the Morphology of Foramen Lacerum.

J Craniofac Surg 2020 May 14. Epub 2020 May 14.

Uttar Pradesh University of Medical Sciences, Saifai, India.

Greater petrosal and deep petrosal nerves unite in foramen lacerum to form vidian nerve which innervate lacrimal, buccal, nasopharynx, and nasal glands. Moreover, the superior part of this foramen transmits lacerum part of internal carotid artery which irrigates major part of brain. Change in the morphology of foramen lacerum may result in compression of neurovascular structures creating neurovascular complications which at times may be fatal/morbid. Read More

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http://dx.doi.org/10.1097/SCS.0000000000006521DOI Listing

Dermoid Cyst in the Postauricular Area.

J Craniofac Surg 2020 May 14. Epub 2020 May 14.

Department of Otorhinolaryngology.

Dermoid cyst is a rare benign tumor and about 7% of occurrences are found in the head and neck region. Its location is almost always in the midline of the body such as the orbit, oral cavity, and nose, but it is rarer in and around the auricle. The authors present a 31-year-old woman with dermoid cyst in the postauricular area which is a rare site for this lesion. Read More

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http://dx.doi.org/10.1097/SCS.0000000000006499DOI Listing

GRP78 and Integrins Play Different Roles in Host Cell Invasion during Mucormycosis.

mBio 2020 Jun 2;11(3). Epub 2020 Jun 2.

Division of Infectious Diseases, The Lundquist Institute for Biomedical Innovation, Harbor-University of California Los Angeles Medical Center, Torrance, California, USA

Mucormycosis, caused by species, is a life-threatening fungal infection that occurs in patients immunocompromised by diabetic ketoacidosis (DKA), cytotoxic chemotherapy, immunosuppressive therapy, hematologic malignancies, or severe trauma. Inhaled spores cause pulmonary infections in patients with hematologic malignancies, while patients with DKA are much more prone to rhinoorbital/cerebral mucormycosis. Here, we show that interacts with glucose-regulated protein 78 (GRP78) on nasal epithelial cells via its spore coat protein CotH3 to invade and damage the nasal epithelial cells. Read More

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http://dx.doi.org/10.1128/mBio.01087-20DOI Listing

Retinoids Augment Thiazolidinedione PPARγ Activation in Oral Cancer Cells.

Anticancer Res 2020 Jun;40(6):3071-3080

Department of Otolaryngology-Head and Neck Surgery, University of Minnesota, Minneapolis, MN, U.S.A.

Background/aim: Head and neck squamous cell carcinoma affects nearly 500,000 people annually. Augmenting PPARγ functional activation is linked with multiple anti-carcinogenic processes in aerodigestive cell lines and animal models. PPARγ/RXRα heterodimers may be key partners in this activation. Read More

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http://dx.doi.org/10.21873/anticanres.14288DOI Listing

Optic neuropathy caused by expanded Onodi cell mucocele.

BMJ Case Rep 2020 Jun 2;13(6). Epub 2020 Jun 2.

Department of Otorhinolaryngology, Asahi General Hospital, Asahi, Chiba, Japan.

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http://dx.doi.org/10.1136/bcr-2020-235311DOI Listing

Intralaryngeal paraganglioma workup and discussion of surgical approach.

BMJ Case Rep 2020 Jun 2;13(6). Epub 2020 Jun 2.

Otolarynology-Head & Neck Surgery, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA.

Laryngeal paragangliomas are an uncommon presentation of head and neck paragangliomas, with laryngeal paragangliomas along with a synchronous paraganglioma being exceptionally rare. We present two challenging cases of laryngeal paragangliomas with extralaryngeal extension, completely resected through a transcervical approach without endolaryngeal disruption, with one case having synchronous bilateral carotid body tumours. Both patients had excellent results with complete tumour resection and no resultant functional impact. Read More

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http://dx.doi.org/10.1136/bcr-2020-234745DOI Listing

Development and validation of the isothermal recombinase polymerase amplification assays for rapid detection of Mycoplasma ovipneumoniae in sheep.

BMC Vet Res 2020 Jun 1;16(1):172. Epub 2020 Jun 1.

College of Veterinary Medicine, Hebei Agricultural University, No.2596 Lekai South Street, Baoding, Hebei, 071001, People's Republic of China.

Background: Mycoplasmal pneumonia is an important infectious disease that threatens sheep and goat production worldwide, and Mycoplasma ovipneumoniae is one of major etiological agent causing mycoplasmal pneumonia. Recombinase polymerase amplification (RPA) is an isothermal nucleic acid amplification technique, and RPA-based diagnostic assays have been described for the detection of different types of pathogens.

Results: The RPA assays using real-time fluorescence detection (real-time RPA) and lateral flow strip detection (LFS RPA) were developed to detect M. Read More

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http://dx.doi.org/10.1186/s12917-020-02387-3DOI Listing

Smartphone-Based Self-Testing of COVID-19 Using Breathing Sounds.

Telemed J E Health 2020 Jun 2. Epub 2020 Jun 2.

Department of Computer Science & Engineering and University of Bridgeport, Bridgeport, Connecticut, USA.

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http://dx.doi.org/10.1089/tmj.2020.0114DOI Listing

[Nasal metastasis from clear cell renal cell carcinoma: report of two cases].

Zhonghua Bing Li Xue Za Zhi 2020 Jun;49(6):642-644

School of Basic Medicine, Gansu University of Chinese Medicine, Lanzhou 730000, China.

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http://dx.doi.org/10.3760/cma.j.cn112151-20191008-00547DOI Listing

Characterization of Arabica and Robusta Coffees by Ion Mobility Sum Spectrum.

Sensors (Basel) 2020 May 31;20(11). Epub 2020 May 31.

Department of Analytical Chemistry, Faculty of Sciences, Agrifood Campus of International Excellence (ceiA3), IVAGRO, University of Cadiz, 11510 Puerto Real, Spain.

Aroma is one of the main characteristics of coffee specimens. Different mixtures of Arabica and Robusta coffees are usually found in the market to offer specific aroma or flavor profiles to consumers. However, the mixed samples or their proportions are not always identified in the product labels. Read More

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http://dx.doi.org/10.3390/s20113123DOI Listing

The Procoagulant Snake Venom Serine Protease Potentially Having a Dual, Blood Coagulation Factor V and X-Activating Activity.

Toxins (Basel) 2020 May 29;12(6). Epub 2020 May 29.

Department of Molecular and Biomedical Sciences, Jožef Stefan Institute, Jamova cesta 39, SI-1000 Ljubljana, Slovenia.

A procoagulant snake venom serine protease was isolated from the venom of the nose-horned viper (). This 34 kDa glycoprotein, termed SP-VX, possesses five kDa N-linked carbohydrates. Amino acid sequencing showed SP-VX to be a chymotrypsin-like serine protease. Read More

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http://dx.doi.org/10.3390/toxins12060358DOI Listing

Human Nasal Epithelial Organoids for Therapeutic Development in Cystic Fibrosis.

Genes (Basel) 2020 May 29;11(6). Epub 2020 May 29.

Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham (UAB), Birmingham, AL 35294, USA.

We describe a human nasal epithelial (HNE) organoid model derived directly from patient samples that is well-differentiated and recapitulates the airway epithelium, including the expression of cilia, mucins, tight junctions, the cystic fibrosis transmembrane conductance regulator (CFTR), and ionocytes. This model requires few cells compared to airway epithelial monolayer cultures, with multiple outcome measurements depending on the application. A novel feature of the model is the predictive capacity of lumen formation, a marker of baseline CFTR function that correlates with short-circuit current activation of CFTR in monolayers and discriminates the cystic fibrosis (CF) phenotype from non-CF. Read More

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http://dx.doi.org/10.3390/genes11060603DOI Listing

A once-a-day dosage form for the delivery of insulin through the nasal route: in vitro assessment and in vivo evaluation.

Biomater Sci 2013 Mar 8;1(3):306-314. Epub 2012 Nov 8.

School of Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth, Hampshire PO1 2DT, UK.

An in situ thermogelling, mucoadhesive formulation based on N-trimethyl chitosan chloride has been evaluated for its potential to affect the transmucosal delivery of insulin via the nasal route. In vitro studies at a physiologically relevant temperature (ca. 35 °C) have shown that the formulation releases most of its insulin load (ca. Read More

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http://dx.doi.org/10.1039/c2bm00132bDOI Listing

[Ectopic intraseptal tooth as a cause of nasal breathing obstruction].

Laryngorhinootologie 2020 Jun 2. Epub 2020 Jun 2.

Klinik für Hals-, Nasen- und Ohrenheilkunde, Universitätsklinikum Freiburg, Germany.

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http://dx.doi.org/10.1055/a-1176-1785DOI Listing

Comparison of Prodromal Symptoms of Patients with Behavioral Variant Frontotemporal Dementia and Alzheimer Disease.

Dement Geriatr Cogn Disord 2020 Jun 2:1-9. Epub 2020 Jun 2.

Institute of Clinical Medicine, Neurology, University of Eastern Finland, Kuopio, Finland,

Introduction: Behavioral variant frontotemporal dementia (bvFTD) is the most common clinical subtype of frontotemporal lobar degeneration. bvFTD is often characterized by changes in behavior and personality, frequently leading to psychiatric misdiagnoses. On the other hand, substantial clinical overlap with other neurodegenerative diseases, such as Alzheimer disease (AD), further complicates the diagnostics. Read More

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http://dx.doi.org/10.1159/000507544DOI Listing