193,557 results match your criteria Nasal Fracture


Stapes footplate defect as a source of CSF leak and otogenic meningitis in a patient with a cochlear implant.

Ear Nose Throat J 2018 Dec;97(12):E31-E32

Department of Otolaryngology, The Royal Victorian Eye and Ear Hospital, East Melbourne, Australia.

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December 2018

Aggressive fibromatosis of the parotid gland.

Ear Nose Throat J 2018 Dec;97(12):E28-E30

Department of Otolaryngology-Head and Neck Surgery, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.

Extra-abdominal fibromatosis (EAF) is a rare, locally aggressive tumor that originates in fascial structures. It accounts for less than 0.3% of all tumors diagnosed. Read More

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December 2018

Effects of acidic and nonacidic reflux on the eustachian tube: An animal experiment.

Ear Nose Throat J 2018 Dec;97(12):E21-E27

MediENT Ear Nose and Throat Hospital, Halk Sokak no:50/1, Istanbul, Turkey.

We investigated the effects of pepsin/hydrochloric acid and bile acids on eustachian tube function and eustachian tube mucosa in 40 Sprague-Dawley rats. The animals were randomly assigned to groups of 10: one group received pepsin/hydrochloric acid (pepsin/HCl group), another received human bile (human bile group), a third received a mixture of pepsin/HCl and human bile (combination group), and the fourth received isotonic saline solution (control group). Test solutions were applied transnasally three times a day for 10 days. Read More

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December 2018

Destructive lesion of the temporomandibular joint: A case of tophaceous pseudogout.

Ear Nose Throat J 2018 Dec;97(12):E18-E20

Department of Otolaryngology-Head and Neck Surgery, Virginia Commonwealth University, West Hospital, 1200 East Broad St., 12th Floor, South Wing, Suite 313, Box 980146, Richmond, VA 23298-0146, USA.

Tophaceous pseudogout of the temporomandibular joint is a rare entity that clinically and radiographically mimics neoplastic or infectious conditions. Diagnosis requires histopathologic examination. Given the rarity of this condition, there is a paucity of information pertaining to the surgical approach, reconstructive options, and postoperative outcomes. Read More

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December 2018

A fistulating oropharyngeal lesion.

Ear Nose Throat J 2018 Dec;97(12):E15-E17

Department of Otorhinolaryngology-Head and Neck Surgery, Mayo Clinic Arizona, 5777 E. Mayo Blvd., Phoenix, AZ 85084, USA.

Post-transplant lymphoproliferative disorder (PTLD) is a unifying term for a spectrum of lymphoid expansion entities brought about by immunosuppression. It can present throughout the head and neck, and tonsillar involvement is not limited to children. We report the case of a 67-year-old woman who developed odynophagia associated with putrid halitosis 4 months after she had undergone renal transplantation. Read More

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December 2018

Red ear syndrome: Perspectives for the otolaryngologist.

Ear Nose Throat J 2018 Dec;97(12):E11-E14

Department of Otolaryngology, Lenox Hill Hospital/Northwell Health, 110-11 72nd Ave., Suite 1B, Forest Hills, NY 11375, USA.

Red ear syndrome (RES) is an unusual, often unrecognized condition that has rarely been reported in the otolaryngology literature despite the presence of symptoms and associated disorders of relevance to the otolaryngologist. When present, RES may have diagnostic value when uncertainties arise in cases of sinus headache and referred otalgia. Despite the appearance of a distinctive red ear, as well as symptoms and associated disorders relating to otolaryngology, discussion of RES is generally limited to neurology-based publications. Read More

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December 2018

An unusual presentation of papillary thyroid carcinoma in a pediatric patient: A case report.

Ear Nose Throat J 2018 Dec;97(12):E7-E10

University of Arizona College of Medicine - Tucson, 1501 N. Campbell Ave., PO Box 245017, Tucson, AZ 85724, USA.

Cystic neck masses in the pediatric population are common but rarely concerning for malignancy. Given this typically benign nature, they are frequently managed conservatively. Here we present an unusual case of a waxing and waning cystic neck mass in a pediatric patient. Read More

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December 2018

Diagnosis and treatment of laryngopharyngeal reflux: Use of empirical lansoprazole.

Ear Nose Throat J 2018 Dec;97(12):E1-E6

Department of Otolaryngology, Cerrahpaşa Medical Faculty, Istanbul University, Cerrahpasa Yerleşkesi, Fatih 34098, Istanbul, Turkey.

The objective of this study was to evaluate the effectiveness of empirical medical treatment in patients with laryngopharyngeal reflux (LPR) disease by scoring the findings and symptoms. Hence, 122 patients were examined at the voice laboratory with a laryngovideostroboscopic device, and all results were recorded for further evaluation. Patients were treated with lansoprazole twice a day. Read More

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December 2018

Evaluation of bendable surgical suction devices made of shape-memory alloy for the endonasal transsphenoid removal of pituitary tumors.

Ear Nose Throat J 2018 Dec;97(12):413-416

Department of Medical Engineering, Fraunhofer Institute for Machine Tools and Forming Technology, Nöthnitzer Straße 44, 01187 Dresden, Germany.

In minimally invasive surgeries, it can be difficult to reach desired anatomic areas with rigid instruments, especially when obstacles are present in the surgical corridor (e.g., during transnasal pituitary surgery). Read More

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December 2018

Endoscopic medialization middle turbinoplasty in endoscopic sinus surgery.

Ear Nose Throat J 2018 Dec;97(12):404-410

Department of Otolaryngology-Head and Neck Surgery, Tufts University School of Medicine, Tufts Medical Center, 800 Washington St., Box 850, Boston, MA 02111, USA. Email:

Recurrence of sinonasal disease can be caused by many factors, including lateralization of the middle turbinate as a complication of endoscopic sinus surgery (ESS). Different ESS procedures have been tried to prevent this complication. We conducted a prospective study to determine if medialization is an effective means of lateralizing the middle turbinate. Read More

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December 2018

KTP-laser-assisted endoscopic management of glomus tympanicum tumors: A case series.

Ear Nose Throat J 2018 Dec;97(12):399-402

Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, 801 Welch Rd., Stanford, CA 94035, USA.

Endoscopic technology is widely used in rhinology and anterior skull base surgery, but it has been less quickly incorporated into otologic practice. The design of the instrumentation forces surgeons to work one-handed and limits depth perception. Nevertheless, endoscopy also offers wide fields of view and access to spaces that are typically difficult to visualize. Read More

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December 2018

Association of Ménière disease with human leukocyte antigen in Taiwanese population.

Ear Nose Throat J 2018 Dec;97(12):396-402

College of Medicine, Chang Gung University, Taoyuan, Taiwan.

The etiology of Ménière disease (MD) is multifactorial; genetic factors seem to play an important role. The associations between MD and human leukocyte antigen (HLA) status have been studied previously in several populations and have shown that the HLA alleles imparting susceptibility varied. In the present study, we explored HLA status in Taiwanese patients with definitive MD. Read More

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December 2018

Unforeseen consequence of alkaline water therapy for laryngopharyngeal reflux.

Ear Nose Throat J 2018 Dec;97(12):394-395

Department of Otolaryngology-Head and Neck Surgery, Philadelphia College of Osteopathic Medicine, Philadelphia, PA, USA.

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December 2018

In-office sinonasal procedures in the elderly.

Ear Nose Throat J 2018 Dec;97(12):392-393

Department of Otolaryngology-Head and Neck Surgery, McGill University, Montreal, Canada.

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December 2018

An unusual case of persistent dysphagia.

Ear Nose Throat J 2018 Dec;97(12):391

Department of Otolaryngology-Head and Neck Surgery, West Virginia University School of Medicine, Morgantown, WV, USA.

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December 2018

Huge neck lymphangioma removed in toto with minimal access.

Ear Nose Throat J 2018 Dec;97(12):389-390

Department of ENT and Head and Neck Surgery, Maulana Azad Medical College, New Delhi, India.

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December 2018

Laryngeal hereditary hemorrhagic telangiectasia.

Ear Nose Throat J 2018 Dec;97(12):388

Laboratory of Phonetics, Faculty of Psychology, Research Institute for Language Sciences and Technology, University of Mons, Mons, Belgium.

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December 2018

The root cause of physician burnout cannot be solved with resilience efforts [Editorial].

Authors:
Michael M Johns

Ear Nose Throat J 2018 Dec;97(12):386

USC Voice Center, Division Director, Laryngology, University of Southern California, Los Angeles, CA, USA.

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December 2018

Corticosteroid use and increased CXCR2 levels on leukocytes are associated with lumacaftor/ivacaftor discontinuation in cystic fibrosis patients homozygous for the F508del CFTR mutation.

PLoS One 2018 12;13(12):e0209026. Epub 2018 Dec 12.

Department of Pediatrics, National Jewish Health, Denver, CO, United States of America.

Cystic fibrosis (CF) is the most common life-shortening genetic disease and is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Several current therapies aim at improving availability and/or function of the mutant CFTR proteins. The combination therapeutic lumacaftor/ivacaftor (Orkambi, luma/iva) partially corrects folding and potentiates CFTR function impaired by the F508del mutation. Read More

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December 2018

Impact of surfactant administration through a thin catheter in the delivery room: A quality control chart analysis coupled with a propensity score matched cohort study in preterm infants.

PLoS One 2018 12;13(12):e0208252. Epub 2018 Dec 12.

Department of Pediatrics, University of Rennes 1,Rennes, France.

Introduction: Most infants born before 30 weeks gestational age (GA) develop respiratory distress syndrome soon after birth. Methods of surfactant administration that avoid ventilation have been recently introduced. The aim of this study was to evaluate the impact of implementing a new procedure of less invasive surfactant administration (LISA) and determine whether it is associated with an improvement in respiratory outcome. Read More

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December 2018

Lower allergen levels in hypoallergenic Curly Horses? A comparison among breeds by measurements of horse allergens in hair and air samples.

PLoS One 2018 12;13(12):e0207871. Epub 2018 Dec 12.

Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-Universität Bochum (IPA), Bochum, Germany.

Background: Exposure to horses can cause severe allergic reactions in sensitized individuals. The breed, American Bashkir Curly Horse is categorized as hypoallergenic, primarily due to reports of allergic patients experiencing fewer symptoms while handling this special breed. The possible reasons for this phenomenon could be lower allergen production and/or reduced allergen release into the air because of increased sebum content in their skin and hair compared to other breeds. Read More

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December 2018
1 Read

The Epidemiology of Otosclerosis in a British Cohort.

Otol Neurotol 2019 Jan;40(1):22-30

University College London Ear Institute, University College London.

Objective: To analyse the epidemiology of otosclerosis in a British cohort collected between 2011 and 2017.

Design: Retrospective cohort study.

Setting: Five UK ENT Departments. Read More

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January 2019

Hypohidrotic Ectodermal Dysplasia: A Rare Disorder with Bilateral Infantile Glaucoma.

J Glaucoma 2018 Dec 11. Epub 2018 Dec 11.

Glaucoma and anterior segment, Dr. Shroff's charity eye hospital, Delhi.

Ectodermal dysplasia is a disorder that occurs due to abnormalities of ectodermal structures such as skin, teeth, hair, nails, and eccrine glands. Approximately 200 different conditions have been identified as ectodermal dysplasia, the most common being hypohidrotic ectodermal dysplasia (HED). It is characterized by hypotrichosis (sparse scalp or body hair), hypodontia (absent or malformed teeth) and hypohidrosis (reduced ability to sweat). Read More

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December 2018
1 Read

Comparisons of skin toxicity in patients with extranodal nasal-type natural killer/T-cell lymphoma after treatment with intensity-modulated radiotherapy and conventional radiotherapy.

J Cancer Res Ther 2018 Dec;14(Supplement):S975-S979

Department of Radiation Oncology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province 450052, P.R. China.

Background: Intensity-modulated radiation therapy (IMRT) has been more widely used in extranodal nasal-type natural killer/T-cell lymphoma (NKTCL) because it can maximally improve the local control rate of tumor and reduce the radiation dose received by surrounding normal tissues. However, there has been no consensus on whether IMRT can help to lower the toxic and adverse reactions caused by radiation therapy. The aim of this study is to compare skin toxicity caused by IMRT and conventional radiotherapy in Stage I-II NKTCL. Read More

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December 2018
1 Read

Essential oils and functional herbs for healthy aging.

Neural Regen Res 2019 Mar;14(3):441-445

School of Pharmacy and Applied Science, La Trobe Institute for Molecular Sciences, La Trobe University, Bendigo, Australia.

As total life expectancy increases, the prevalence of age-related diseases such as diabetes and Alzheimer's disease is also increasing. Many hypotheses about Alzheimer's disease have been developed, including cholinergic neuron damage, oxidative stress, and inflammation. Acetylcholine is a major neurotransmitter in the brain and cholinergic deficits leads to cognitive dysfunction and decline. Read More

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March 2019
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Oncocytic Sialolipoma of Parotid Gland: Case Report and Literature Review.

Head Neck Pathol 2018 Dec 11. Epub 2018 Dec 11.

Department of Ear, Nose and Throat, Guy's and St Thomas' NHS Foundation Trust, Great Maze Pond, London, SE1 9RT, UK.

Oncocytic sialolipoma is a very rare tumor of which only three cases have been reported. This entity is considered to be a variant of sialolipoma which harbours oncocytic nodules within a well-circumscribed lipomatous mass. We report a parotid mass in 73-year-old female that was difficult to diagnose in imaging and on biopsy. Read More

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December 2018

Influenza B in a temperate region of northern India 2010-2016: co-circulation of the two lineages with northern hemispherical seasonality.

Virusdisease 2018 Dec 26;29(4):553-559. Epub 2018 Sep 26.

2National Institute of Virology, Pune, Mahrashtra India.

Scant data exist about the epidemiology of influenza B in India. We set out to address the epidemiology of influenza B in a temperate region of northern India from 2010 to 2016. Outpatient and inpatient surveillance was conducted in patients presenting with acute respiratory infection in a northern Indian hospital from September 2010 till April 2016. Read More

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December 2018

Significant Neutrophilic Emperipolesis in Squamous Cell Carcinoma.

Case Rep Oncol Med 2018 13;2018:1301562. Epub 2018 Nov 13.

Department of Ear, Nose, and Throat Disease, Bakırköy Sadi Konuk Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.

A 53-year-old man was admitted for tooth mobility. A mass was identified at the tooth base by CT. Histopathology of the excisional biopsy revealed a moderately differentiated squamous cell carcinoma. Read More

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November 2018

Ability of Swept-Source Optical Coherence Tomography to Detect Retinal and Choroidal Changes in Patients with Multiple Sclerosis.

J Ophthalmol 2018 13;2018:7361212. Epub 2018 Nov 13.

Ophthalmology Department, Miguel Servet University Hospital, Zaragoza, Spain.

Purpose: To evaluate the ability of new swept-source (SS) optical coherence tomography (OCT) technology to detect changes in retinal and choroidal thickness in patients with multiple sclerosis (MS).

Methods: A total of 101 healthy and 97 MS eyes underwent retinal and choroidal assessment using SS Triton OCT (Topcon). Macular thickness and peripapillary data (retinal, ganglion cell layer (GCL+, GCL++) and retinal nerve fiber layer (RNFL) thickness) were analyzed, including choroidal thickness evaluation. Read More

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November 2018

Could Music Minimize Discomfort and Pain During Office-Based ENT Surgery?

Int J Otolaryngol 2018 14;2018:6480346. Epub 2018 Nov 14.

Full Professor Unit of Otolaryngology, Campus Bio-Medico University, Rome, Italy.

Background: Video-assisted endoscopic radiofrequency inferior turbinate volume reduction (RFVTR) is one of the most common surgical therapies for inferior turbinate hypertrophy (ITH). Despite all the technical and surgical advancement, it is advisable to reduce as low as possible the intraoperative discomfort. The aim of this study is to evaluate the role of music in reducing patient discomfort during RFVTR. Read More

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November 2018

Nasal Cytology: A Comparative Study of Two Different Techniques of Processing-Smeared versus Cytocentrifuged Slides.

Mediators Inflamm 2018 14;2018:1640180. Epub 2018 Nov 14.

1st Otorhinolaryngology Unit, Department of Neuroscience, Azienda Ospedaliero Universitaria Pisana, Via Paradisa 2, 56124 Pisa, Italy.

Nasal cytology is a precious tool to study nasal disorders, but in current literature, there is no consensus on the standardization of the processing procedure of the obtained samples. Therefore, we decided to test on specimens obtained by nasal scraping, a common way of nasal specimen sampling, two different processing techniques, smear and cytocentrifugation, and compare them in terms of inflammatory cell content, quality of slides, and validity on clinical assessment. We analyzed 105 patients with suspected sinonasal diseases, and in each patient, we performed nasal cytology with both techniques. Read More

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November 2018

Nasal function and CPAP compliance.

Auris Nasus Larynx 2018 Dec 8. Epub 2018 Dec 8.

Department of Otorhinolaryngology, Toho University Graduate School of Medicine, Japan; Department of Otorhinolaryngology, Toho University Omori Medical Center, Japan. Electronic address:

Objective: Continuous positive airway pressure (CPAP) is the mainstay therapy for patients with obstructive sleep apnea (OSA) however compliance with CPAP is variable. Nasal ailments, such as nasal congestion are frequently mentioned as a cause for CPAP non-compliance, and potentially could be addressed prior to CPAP initiation, however, no specific criteria or recommendations for the evaluation and management of these patients exist. The aim of this retrospective study is to evaluate the effects of nasal anatomic features and disease on adherence to CPAP therapy for patients with OSA and determine the indications for pre-CPAP nasal treatment by using data obtained at clinical examination. Read More

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December 2018

Reversal of hoarseness with recognition of Ortner syndrome in a patient with severe mitral regurgitation.

J Cardiol Cases 2013 Feb 8;7(2):e48-e50. Epub 2012 Dec 8.

Department of Second Section of Cardiology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 5 Fuxing Street, Guishan Township, Taoyuan County 33305, Taiwan.

Loss of voice due to vocal cord paralysis, as in Ortner syndrome, is secondary to left recurrent laryngeal nerve palsy. Cardiovascular cause should be listed as a differential diagnosis of hoarseness and is incumbent upon the diagnostic physician to be familiar with the condition. A 56-year-old male presented to our emergency department with shortness of breath due to severe mitral regurgitation. Read More

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February 2013

Refractory variant angina with a seasonal trend treated with sarpogrelate hydrochloride.

J Cardiol Cases 2012 Dec 19;6(6):e176-e178. Epub 2012 Aug 19.

Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, 1-847, Amanuma-cho, Omiya-ku, Saitama 330-8503, Japan.

A 68-year-old man was referred to our hospital for the evaluation and treatment of chest discomfort and syncope. He was diagnosed with variant angina by prolonged ischemic episode with ST-segment elevation in leads II, III, and aV. His symptoms had a seasonal trend and occurred only from April to September. Read More

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December 2012

Long-term efficacy and dose-finding trial of Japanese cedar pollen SLIT tablet.

J Allergy Clin Immunol Pract 2018 Dec 8. Epub 2018 Dec 8.

Department of Otolaryngology, Head and Neck Surgery, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan.

Background: Japanese cedar (JC) pollinosis is a common allergic rhinitis in Japan. The JC pollen SLIT tablet was developed using the highest concentration of JC pollen extract.

Objective: This was a randomized, double-blind, placebo-controlled phase II/III trial to investigate the optimal dose of the JC pollen SLIT tablet and examine long-term efficacy and safety for 3 years with the selected dose, and 2-year follow-up. Read More

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December 2018

Activity and pharmacology of homemade silver nanoparticles in refractory metastatic head and neck squamous cell cancer.

Head Neck 2018 Dec 11. Epub 2018 Dec 11.

Department of Internal Medicine, UT Southwestern Medical Center, Dallas, Texas.

Background: Silver nanoparticles (AgNP) show efficacy in cancer cell lines. We present the first in-human outcome of AgNP in a cancer patient.

Methods: Homemade AgNP solution is manufactured using online instructions by a 78-year old male. Read More

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December 2018

Osteitis is associated with dysregulated pro-osteoblastic activity in patients with nasal polyps.

Laryngoscope 2018 Dec 11. Epub 2018 Dec 11.

From the Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, U.S.A.

Objectives/hypothesis: The overlying inflammatory mucosa plays a crucial role in the initiation of osteitis; however, the molecular mechanism is unclear. The objective of this study was to explore the bone morphogenetic protein (BMP) pathway and to correlate the expression of key signaling molecules with the degree of osteitis in patients with chronic rhinosinusitis with nasal polyps (CRSwNP).

Study Design: Prospective experimental analysis. Read More

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December 2018

Wait times for endoscopic sinus surgery influence patient-reported outcome measures in patients with chronic rhinosinusitis who fulfill appropriateness criteria.

Int Forum Allergy Rhinol 2018 Dec 10. Epub 2018 Dec 10.

Division of Rhinology, Department of Otolaryngology-Head and Neck Surgery, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.

Background: Previous studies on the impact of wait times for endoscopic sinus surgery (ESS) in medically recalcitrant chronic rhinosinusitis (rCRS) have not examined its influence on the 5 distinct symptoms domains of the 22-item Sino-Nasal Outcome Test (SNOT-22), and have not applied evidence-based surgical indications. Our primary study objective was to investigate the impact of ESS wait times on postoperative SNOT-22 global and symptom domain scores in patients with rCRS deemed "appropriate" surgical candidates.

Methods: This was a retrospective analysis of adult patients with rCRS undergoing ESS, categorized as "appropriate" surgical candidates. Read More

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December 2018

Accelerated Pseudogenization of Trace Amine-Associated Receptor Genes in Primates.

Authors:
S Eyun

Genes Brain Behav 2018 Dec 10:e12543. Epub 2018 Dec 10.

Department of Life Science, Chung-Ang University, Seoul, Korea.

Trace amines (TAs) in the mammalian brain have been investigated for four decades. Trace amine-associated receptors (TAARs) were discovered during the search for receptors activated by TAs. TAARs are considered a second class of vertebrate olfactory receptors and successfully proliferated in conjunction with adaptation to living on the ground to detect carnivore odors. Read More

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December 2018

Venous thromboembolism in head and neck surgery: Risk, outcome, and burden at the national level.

Head Neck 2018 Dec 7. Epub 2018 Dec 7.

Department of Surgery, Tulane University School of Medicine, New Orleans, Louisiana.

Background: Venous thromboembolism (VTE) can complicate major surgeries. This study examines the risk and outcomes of VTE in patients who underwent head and neck surgeries.

Methods: Retrospective cross-sectional analysis utilizing the Nationwide Readmissions Database (2010-2014). Read More

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December 2018

Ototoxicity in locally advanced head and neck cancer patients treated with induction chemotherapy followed by intermediate or high-dose cisplatin-based chemoradiotherapy.

Head Neck 2018 Dec 7. Epub 2018 Dec 7.

Department of Medical Oncology, Radboud University Medical Center, Nijmegen, The Netherlands.

Background: This study evaluated ototoxicity in locally advanced head and neck cancer patients treated in the CONDOR study with docetaxel/cisplatin/5-fluorouracil (TPF) followed by conventional radiotherapy with concomitant cisplatin 100 mg/m on days 1, 22, and 43 (cis100+RT) versus accelerated radiotherapy with concomitant cisplatin weekly 40 mg/m (cis40+ART).

Methods: Sixty-two patients were treated in this study. Audiometry was performed at baseline, during TPF, before start of chemoradiotherapy, and 1, 4, 8, and 12 months after treatment. Read More

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December 2018

Prospective, randomized, controlled, open-label study to compare efficacy of a mineral-rich solution vs normal saline after complete ethmoidectomy.

Eur Arch Otorhinolaryngol 2018 Dec 8. Epub 2018 Dec 8.

CHU Bordeaux, CIC 14-01 IT, 33000, Bordeaux, France.

Purposes: The purpose of this study was to compare the efficacy of a mineral-rich solution vs normal saline solution (0.9% NaCl) following endoscopic complete bilateral ethmoidectomy.

Methods: This was a prospective, multicenter, randomized, controlled, open-label trial in subjects suffering from steroid-resistant sinonasal polyposis. Read More

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December 2018

Incidental findings on 18-FDG PET-CT in head and neck cancer. A retrospective case-control study of incidental findings on 18-FDG PET-CT in patients with head and neck cancer.

Eur Arch Otorhinolaryngol 2018 Dec 10. Epub 2018 Dec 10.

Department of Ear, Nose, and Throat Surgery, Oxford University Hospital NHS Foundation Trust, Oxford, UK.

Purpose: Use of 18-FDG PET-CT is increasing in patients with head and neck cancer, enabling the identification of metastases or synchronous malignancies, but also 'incidental' disease. We aimed to establish the rate of 'incidental' findings resulting from 18-FDG PET-specific imaging, that would not have been otherwise identified on other imaging, in patients with head and neck cancer undergoing staging or surveillance of disease.

Methods: 18-FDG PET-CT was performed for investigation or surveillance. Read More

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December 2018

Establishment of a novel and effective reflux laryngitis model in rabbits: a preliminary study.

Eur Arch Otorhinolaryngol 2018 Dec 10. Epub 2018 Dec 10.

The Department of Otolaryngology-Head and Neck Surgery, Eye, Ear, Nose, and Throat Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200030, China.

Purpose: To establish a novel and effective reflux model with a modified nasogastric aspiration tube and to investigate the association between different types of nasogastric aspiration tubes and reflux laryngitis, we conducted this study.

Methods: Thirty-eight healthy New Zealand albino rabbits (2.5-3. Read More

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December 2018

The application of nasoseptal "rescue" flap technique in endoscopic transsphenoidal pituitary adenoma resection.

Neurosurg Rev 2018 Dec 11. Epub 2018 Dec 11.

Department of Neurosurgery, Qilu Hospital, Shandong University, 107 Wenhua Western Rd., Jinan, 250012, Shandong, China.

To explore the reliability and superiority of nasoseptal "rescue" flap technique in neuroendoscopic transnasal pituitary adenoma resection. Retrospective clinical analysis of 113 cases of endoscopic transsphenoid pituitary adenoma resection with the application of nasoseptal "rescue" flap technology. The reliability and the superiority of the technique were evaluated according to the duration of nasal cavity and sphenoid sinus stage, the incidence of postoperative anosmia, and cerebrospinal rhinorrhea. Read More

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December 2018

Putative Microbial Population Shifts Attributable to Nasal Administration of Streptococcus salivarius 24SMBc and Streptococcus oralis 89a.

Probiotics Antimicrob Proteins 2018 Dec 7. Epub 2018 Dec 7.

Laboratory of Clinical Chemistry and Microbiology, IRCCS Orthopedic Institute Galeazzi, Via Galeazzi 4, 20164, Milan, Italy.

Changes in bacterial composition of nasal microbiota may alter the host's susceptibility to several infectious and allergic diseases such as chronic rhinosinusitis and allergic rhinitis. The aim of this study was to evaluate the effects of 1-week administration of a probiotic product, composed by a combination of Streptococcus salivarius 24SMBc and Streptococcus oralis 89a, on the nostril microbiota. Differences in the nasal microbiota composition were investigated by using a next-generation sequencing approach. Read More

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December 2018

Wide diameter bone-anchored hearing system implants: a comparison of long-term follow-up data between tissue reduction and tissue preservation techniques.

Eur Arch Otorhinolaryngol 2018 Dec 7. Epub 2018 Dec 7.

Department of Otorhinolaryngology, Head and Neck Surgery and Audiology, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, 2100, Copenhagen, Denmark.

Objective: To present long-term data on the Wide Ponto implant bone-anchored hearing system (BAHS) in regards to implant stability, soft tissue reaction and implant loss for two case series undergone either the tissue reduction- or the tissue preservation surgical technique.

Methods: Comparison of two consecutive, prospective case series. Each case series enrolled 24 patients. Read More

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December 2018

MicroRNA‑143‑3p suppresses cell growth and invasion in laryngeal squamous cell carcinoma via targeting the k‑Ras/Raf/MEK/ERK signaling pathway.

Authors:
Feng Zhang Hua Cao

Int J Oncol 2018 Dec 6. Epub 2018 Dec 6.

Ear Nose and Throat Hospital, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, P.R. China.

MicroRNAs (miRNAs or miRs) have been identified as an important regulator in carcinogenesis and other pathological processes. However, the molecular mechanism underlying the function of miRNAs in the progression and development of laryngeal squamous cell carcinoma (LSCC) remains to be fully elucidated. In the present study, the miRNA expression pattern in LSCC tissues was profiled using miRNA microarray analysis. Read More

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December 2018