85,304 results match your criteria Nano Letters [Journal]


Enhanced Luminescence from InGaN/GaN Nano-disk in a wire Array Caused by Surface Potential Modulation during Wet Treatment.

Nanotechnology 2018 Dec 17. Epub 2018 Dec 17.

EE, IIT Bombay, Mumbai, MH, INDIA.

Here we have demonstrated the profound impact of surface potential on the luminescence of an array of InGaN/GaN nano-disk in a wire heterostructure. The change in surface potential is brought about by a combination of dry and successive wet-processing treatments. The photoluminescence (PL) properties are determined as a function of size and height of this array of nano-disks. Read More

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December 2018

Moina macrocopa as a non-target aquatic organism for assessment of ecotoxicity of silver nanoparticles: Effect of size.

Chemosphere 2018 Dec 7;219:713-723. Epub 2018 Dec 7.

Food Engineering and Technology Department, Institute of Chemical Technology, Mumbai 400019, Maharashtra, India.

The release of nanomaterials in water reservoirs is hazardous. Very few reports are available on the interaction of different sized nanoparticles with aquatic organisms and aquatic environment. In the present study, silver nanoparticles (AgNPs) having an average particle size of 20. Read More

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December 2018

Methotrexate-loaded biodegradable polymeric micelles for lymphoma therapy.

Int J Pharm 2018 Dec 14. Epub 2018 Dec 14.

Department of Hematology and Research Laboratory of Hematology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, and Collaborative Innovation Center, Chengdu, 610041, PR China. Electronic address:

Drug resistance and recurrence are the main clinical challenges in chemotherapy of lymphoma. Methotrexate (MTX), especially high dose MTX (HD MTX), is extensively used to treat some aggressive subtypes of lymphoma, such as Burkitt's lymphoma, in order to overcome drug resistance. But poor solubility of the free drug and severe side effects of HD MTX limit its clinical application. Read More

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December 2018

Molecular Tunability of Magnetic Exchange Bias and Asymmetrical Magnetotransport in Metalloporphyrin/Co Hybrid Bilayers.

ACS Nano 2018 Dec 17. Epub 2018 Dec 17.

Molecular spins as individual are promising quantum states for emerging computation technologies. The "on surface" configuration of molecules in proximity to a magnetic film allows control over the orientations of molecular spins and coupling between them. The stacking of planar molecular spins could favor antiferromagnetic interlayer couplings and lead to pinning of the magnetic underlayer via the exchange bias, which is extensively utilized in ultrafast and high-density spintronics. Read More

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December 2018

Membrane Wrapping Efficiency of Elastic Nanoparticles During Endocytosis: Size and Shape Matter.

ACS Nano 2018 Dec 17. Epub 2018 Dec 17.

Using coarse-grained molecular dynamics simulations, we systematically investigate the receptor-mediated endocytosis of elastic nanoparticles (NPs) with different sizes, ranging from 25 nm to 100 nm, and shapes, including sphere-like, oblate-like and prolate-like. Simulation results provide clear evidence that the membrane wrapping efficiency of NPs during endocytosis is a result of competition between receptor diffusion kinetics and thermodynamic driving force. The receptor diffusion kinetics refer to the kinetics of receptor recruitment that are affected by the contact edge length between the NP and membrane. Read More

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December 2018

Influence of Cracks on the Optical Properties of Silver Nanocrystals Supracrystal Films.

ACS Nano 2018 Dec 17. Epub 2018 Dec 17.

Physical properties of nanocrystals self-assembled into 3D superlattices called supracrystals are highly specific with unexpected behavior. The best example to support such claim was given, through STM/STS experiments at low temperature, of very thick supracrystals (around 1000 layers) where it was possible to image the surpracrystal surface and study their electronic properties. From previous studies, we know the optical properties of Ag nanocrystals self-assembled in hexagonal network (2D) or forming small 3D superlattices (from around 2 to 7 layers) are governed by dipolar interactions. Read More

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December 2018

The adjuvant AlhydroGel elicits higher antibody titres than AddaVax when combined with HIV-1 subtype C gp140 from CAP256.

PLoS One 2018 17;13(12):e0208310. Epub 2018 Dec 17.

Institute of Infectious Disease and Molecular Medicine, Faculty of Health Science, University of Cape Town, South Africa.

With the HIV-1 epidemic in southern Africa still rising, a prophylactic vaccine against the region's most prolific subtype (subtype C) would be a significant step forward. In this paper we report on the effect of 2 different adjuvants, AddaVax and AlhydroGel, formulated with HIV-1 subtype C gp140, on the development of binding and neutralising antibody titres in rabbits. AddaVax is a squalene-based oil-in-water nano-emulsion (similar to MF59) which can enhance both cellular and humoral immune responses, whilst AlhydroGel (aluminium hydroxide gel) mainly drives a Th2 response. Read More

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December 2018

Preparation and in vitro / in vivo evaluation of 6-Gingerol TPGS/PEG-PCL polymeric micelles.

Pharm Dev Technol 2018 Dec 17:1-30. Epub 2018 Dec 17.

a Department of Pharmaceutics, School of Pharmacy, Center for Nano Drug/Gene Delivery and Tissue Engineering , Jiangsu University , Zhenjiang 212013 , People's Republic of China.

6-Gingerol, an active herbal ingredient of ginger, has various bioactivities such as anti-neurodegenerative disease, anti-inflammatory and so on. The aim of the present study was to enhance the oral bioavailability and brain distribution of 6-Gingerol via polymeric micelles. A polymeric micelles drug delivery system of 6-Gingerol consisting of D-α-Tocopheryl polyethylene glycol 1000 succinate (TPGS) and Poly (ethylene glycol)-poly (ε-caprolactone) (PEG-PCL) was prepared via solvent injection method. Read More

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December 2018

Design and synthesis of mixed micellar system for enhanced anticancer efficacy of Paclitaxel through its co-delivery with Naringin.

Drug Dev Ind Pharm 2018 Dec 17:1-40. Epub 2018 Dec 17.

a H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences , Karachi University , Karachi , 74200 , Pakistan.

Emergence of multidrug resistance (MDR) has limited the success of chemotherapeutic agents. Reversal of drugs efflux systems through combination therapy has got wider attention for increasing anticancer drugs efficacy. This study aims at co-encapsulation of Paclitaxel with Naringin in mixed polymeric micelles for enhanced anticancer activity of the drug. Read More

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December 2018

Low Residual Carrier Concentration and High Mobility in 2D Semiconducting BiOSe.

Nano Lett 2018 Dec 17. Epub 2018 Dec 17.

Center for Nanochemistry, Beijing Science and Engineering Center for Nanocarbons, Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering , Peking University , Beijing 100871 , P. R. China.

The air-stable and high-mobility two-dimensional (2D) BiOSe semiconductor has emerged as a promising alternative that is complementary to graphene, MoS, and black phosphorus for next-generation digital applications. However, the room-temperature residual charge carrier concentration of 2D BiOSe nanoplates synthesized so far is as high as about 10-10 cm, which results in a poor electrostatic gate control and unsuitable threshold voltage, detrimental to the fabrication of high-performance low-power devices. Here, we first present a facile approach for synthesizing 2D BiOSe single crystals with ultralow carrier concentration of ∼10 cm and high Hall mobility up to 410 cm V s simultaneously at room temperature. Read More

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December 2018
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Fabrication of plumbagin on silver nanoframework for tunable redox modulation: Implications for therapeutic angiogenesis.

J Cell Physiol 2018 Dec 17. Epub 2018 Dec 17.

Biological Materials Laboratory, CSIR-Central Leather Research Institute, Chennai, India.

The redox state of the endothelial cells plays a key role in the regulation of the angiogenic process. The modulation of the redox state of endothelial cells (ECs) could be a viable target to alter angiogenic response. In the present work, we synthesized a redox modulator by caging 5-hydroxy 2-methyl 1, 4-napthoquinone (Plumbagin) on silver nano framework (PCSN) for tunable reactive oxygen species (ROS) inductive property and tested its role in ECs during angiogenic response in physiological and stimulated conditions. Read More

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December 2018

Near-Infrared Afterglow Luminescent Aggregation-Induced Emission Dots with Ultrahigh Tumor-to-Liver Signal Ratio for Promoted Image-Guided Cancer Surgery.

Nano Lett 2018 Dec 17. Epub 2018 Dec 17.

Afterglow imaging through the collection of persistent luminescence after the stopping of light excitation holds enormous promise for advanced biomedical uses. However, efficient near-infrared (NIR)-emitting afterglow luminescent materials and probes (particularly the organic and polymeric ones) are still very limited, and their in-depth biomedical applications such as precise image-guided cancer surgery are rarely reported. Here, we design and synthesize a NIR afterglow luminescent nanoparticle with aggregation-induced emission (AIE) characteristics (named AGL AIE dots). Read More

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December 2018
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Green hydrogen separation from nitrogen by mixed matrix membranes consisting of nanosized sodalite crystals.

ChemSusChem 2018 Dec 17. Epub 2018 Dec 17.

State Key Laboratory of Heavy Oil Processing, Key Laboratory of Catalysis, China National Petroleum Corp. (CNPC) China University of Petroleum (East China), Qingdao 266555, People's Republic of China, CHINA.

Nanosized sodalite crystals (Nano-SOD) are used as active filler to prepare mixed matrix membranes (MMMs) for promoting the H2/N2 gas separation performance. The Nano-SOD with extremely small crystallites (40-50 nm) are synthesized from a colloidal suspension free of organic structural directing agent, and uniformly dispersed in the Polyetherimide (PEI) matrix. The Nano-SOD filler with a proper aperture size (2. Read More

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December 2018

Small asymmetric Brownian objects self-align in nanofluidic channels.

Soft Matter 2018 Dec 17. Epub 2018 Dec 17.

Soft Condensed Matter, Debye Institute for Nanomaterials Science, Department of Physics, Utrecht University, Princetonplein 1, 3584 CC, Utrecht, The Netherlands.

Although the self-alignment of asymmetric macro-sized objects of a few tens of microns in size have been studied extensively in experiments and theory, access to much smaller length scales is still hindered by technical challenges. We combine molecular dynamics and stochastic rotation dynamics techniques to investigate the self-orientation phenomenon at different length scales, ranging from the micron to the nano scale by progressively increasing the relative strength of diffusion over convection. To this end, we model an asymmetric dumbbell particle in Hele-Shaw flow and explore a wide range of Péclet numbers (Pe) and different particle shapes, as characterized by the size ratio of the two dumbbell spheres (R[combining tilde]). Read More

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December 2018

A new DNA sensor system for specific and quantitative detection of mycobacteria.

Nanoscale 2018 Dec 17. Epub 2018 Dec 17.

Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark. and Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Aarhus, Denmark.

In the current study, we describe a novel DNA sensor system for specific and quantitative detection of mycobacteria, which is the causative agent of tuberculosis. Detection is achieved by using the enzymatic activity of the mycobacterial encoded enzyme topoisomerase IA (TOP1A) as a biomarker. The presented work is the first to describe how the catalytic activities of a member of the type IA family of topoisomerases can be exploited for specific detection of bacteria. Read More

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December 2018

Genetically-engineered protein prodrug-like nanoconjugates for tumor-targeting biomimetic delivery via a SHEATH strategy.

Nanoscale 2018 Dec 17. Epub 2018 Dec 17.

State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Science, Shanghai 201203, China. and University of Chinese Academy of Science, Beijing, China.

The delivery issue is a major hurdle against drug development and the clinical application of the cytoplasmic active proteins (e.g., ribosome-inactivating proteins, RIPs). Read More

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December 2018

Excitonic Complexes and Emerging Interlayer Electron-Phonon Coupling in BN Encapsulated Monolayer Semiconductor Alloy: WS0.6Se1.4.

Nano Lett 2018 Dec 17. Epub 2018 Dec 17.

Monolayer transition metal dichalcogenides (TMDs) possess superior optical properties, including the valley degree of freedom that can be accessed through the excitation light of certain helicity. While WS2 and WSe2 are known for their excellent valley polarization due to the strong spin-orbit coupling, the optical bandgap is limited by the ability to choose from only these two materials. This limitation can be overcome through the monolayer alloy semiconductor, WS2xSe2(1-x), which promises an atomically thin semiconductor with tunable bandgap. Read More

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December 2018

Strategies to Improve Luminescence Efficiency of Metal-Halide Perovskites and Light-Emitting Diodes.

Adv Mater 2018 Dec 17:e1804595. Epub 2018 Dec 17.

Department of Materials Science and Engineering, Institute of Engineering Research, Research Institute of Advanced Materials, Nano Systems Institute (NSI), BK21 PLUS SNU Materials Division for Educating Creative Global Leaders, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, Republic of Korea.

Metal-halide perovskites (MHPs) are well suited to be vivid natural color emitters due to their superior optical and electrical properties, such as narrow emission linewidths, easily and widely tunable emission wavelengths, low material cost, and high charge carrier mobility. Since the first development of MHP light-emitting diodes (PeLEDs) in 2014, many researchers have tried to understand the properties of MHP emitters and the limitations to luminescence efficiency (LE) of PeLEDs, and have devoted efforts to increase the LE of MHP emitters and PeLEDs. Within three and half years, PeLEDs have shown rapidly increased LE from external quantum efficiency ≈0. Read More

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December 2018

Incorporation of metal-organic framework amino-modified MIL-101 into glycidyl methacrylate monoliths for nano LC separation.

J Sep Sci 2018 Dec 17. Epub 2018 Dec 17.

Department of Analytical Chemistry, Faculty of Chemistry, University of Valencia, Valencia, Spain.

Metal-organic frameworks consisting of amino-modified MIL-101(M: Cr, Al and Fe) crystals have been synthesized and subsequently incorporated to glycidyl methacrylate (GMA) monoliths to develop novel stationary phases for nano-liquid chromatography. Two incorporation approaches of these materials in monoliths were explored. The MOF materials were firstly attached to the pore surface through reaction of epoxy groups present in the parent GMA-based monolith. Read More

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December 2018

Molecular Design of β-Sheet Peptide for Multi-Modal Analysis of Disease.

Angew Chem Int Ed Engl 2018 Dec 16. Epub 2018 Dec 16.

National Center for Nanoscience and Technology, CAS Key Laboratory for Biological Effects of Nanomaterials and Nano- safety, No. 11 Beiyitiao, Zhongguancun, 100190, Beijing, CHINA.

Intermolecular forces fundamentally constrain peptide conformation. However, the exact role of each intermolecular force in constraining peptide conformation remains poorly understood. In this work, we uncover that aromatic-aromatic interactions predominantly drive peptides into β-sheets, and hydrophobic effect fundamentally determines the assembly speed of peptides. Read More

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December 2018

Boric Acid as a Coupling Agent for Preparation of Phenolic Resin Containing Boron and Silicon with Enhanced Char Yield.

Macromol Rapid Commun 2018 Dec 17:e1800702. Epub 2018 Dec 17.

Department of Applied Chemistry, School of Natural and Applied Sciences, Northwestern Polytechnical University, Xi'an 710072, China.

In this study, an innovative, facile, and low-cost method is developed to prepare phenolic resin (PR) containing boron and silicon (BSiPR). BSiPR is synthesized by a solvent-free, one-pot method using boric acid as the coupling agent instead of silane, and methyltriethoxysilane as the silicon source. The results show that boron and silicon elements are introduced into PR via BOC and BOSi structures. Read More

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December 2018

Recent Advances in Transparent Electronics with Stretchable Forms.

Adv Mater 2018 Dec 17:e1804690. Epub 2018 Dec 17.

Nano Science Technology Institute, Department of Materials Science and Engineering, Yonsei University, Seoul, 03722, Republic of Korea.

Advances in materials science and the desire for next-generation electronics have driven the development of stretchable and transparent electronics in the past decade. Novel applications, such as smart contact lenses and wearable sensors, have been introduced with stretchable and transparent form factors, requiring a deeper and wider exploration of materials and fabrication processes. In this regard, many research efforts have been dedicated to the development of mechanically stretchable, optically transparent materials and devices. Read More

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December 2018

Illustration and application of enhancing effect of arginine on interactions between nano-clays: self-healing hydrogels.

Soft Matter 2018 Dec 17. Epub 2018 Dec 17.

State Key Laboratory of Organic-Inorganic Composite Materials, Beijing University of Chemical Technology, 15 Beisanhuan East Road, Chaoyang District, Beijing, 100029, China.

Nano-clays (NCs) as a representative type of nano-materials are a source of inspiration for design of new biomedical materials with excellent performances. Research has shown that guanidinium ions (Gu+) can form non-covalent salt-bridge interactions with NCs, serving as "molecular glue" in the fabrication of NC-based composites. However, synthesis of the Gu+-containing molecules is always not easy. Read More

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December 2018

An all-in-one Sn-Co alloy as a binder-free anode for high-capacity batteries and its dynamic lithiation in situ.

Chem Commun (Camb) 2018 Dec 17. Epub 2018 Dec 17.

Department of Materials Science and Engineering, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53211, USA.

A three-dimensional all-in-one Sn-Co alloy anode is reported for the first time, which delivers a high capacity along with a stable coulombic efficiency as well as good temperature tolerance. The binder-free electrode eliminates the complexity of conventional slurry preparation while maintaining an integrated scaffold, which provides space to accommodate volume expansion, as confirmed by an in situ transmission electron microscopy study. Read More

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December 2018

Visualization of inhomogeneous current distribution on ZrO-coated LiCoO thin-film electrodes using scanning electrochemical cell microscopy.

Chem Commun (Camb) 2018 Dec 17. Epub 2018 Dec 17.

Graduate School of Environmental Studies, Tohoku University, 6-6-11-604, Aramaki Aoba, Aoba-ku, Sendai 980-8579, Japan and WPI-Advanced Institute for Materials Research (AIMR), Tohoku University, 2-1-1-509, Katahira, Aoba-ku, Sendai 980-8577, Japan.

Cathode surface coating with metal-oxide thin layers has been intensively studied to improve the cycle durability of lithium-ion batteries. A comprehensive understanding of the metal-oxide morphology and the local electrochemical properties is essential for figuring out the metal-oxide coating effect. In this study, scanning electrochemical cell microscopy (SECCM) is used to analyze the surface morphology with high spatial resolution, together with the local electrochemical properties. Read More

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December 2018

Guar-Based Injectable Thermoresponsive Hydrogel as a Scaffold for Bone Cell Growth and Controlled Drug Delivery.

ACS Omega 2018 Nov 9;3(11):15158-15167. Epub 2018 Nov 9.

Department of Chemistry and Center for Integrative Nanotechnology Sciences, University of Arkansas at Little Rock, 2801 South University Avenue, Little Rock, Arkansas 72204, United States.

In this study, an injectable thermoresponsive hydroxypropyl guar--poly(-vinylcaprolactam) (HPG--PNVCL) copolymer was synthesized by graft polymerization. The reaction parameters such as temperature, time, monomer, and initiator concentrations were varied. In addition, the HPG--PNVCL copolymer was modified with nano-hydroxyapatite (n-HA) by in situ covalent cross-linking using divinyl sulfone (DVS) cross-linker to obtain HPG--PNVCL/n-HA/DVS composite material. Read More

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November 2018
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The delivery of mRNA to colon inflammatory lesions by lipid-nano-particles containing environmentally-sensitive lipid-like materials with oleic acid scaffolds.

Heliyon 2018 Dec 3;4(12):e00959. Epub 2018 Dec 3.

Laboratory of DDS Design and Drug Disposition, Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1, Inohana, Chuo-ku, Chiba-shi, Chiba 260-8675, Japan.

An mRNA gene therapy represents a potentially promising therapeutic for curing inflammatory diseases. The transient nature of the gene expression of mRNA would be expected to be beneficial for avoiding undesired side effects. Since the mRNA is a vulnerable molecule, a development of a carrier that can deliver the mRNA to the cytoplasm has a high priority. Read More

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December 2018

Verification of Long-Term Genetic Stability of hMSCs during Subculture after Internalization of Sunflower-Type Nanoparticles (SF-NPs).

Theranostics 2018 5;8(20):5548-5561. Epub 2018 Nov 5.

Laboratory of Nano-regenerative Medical Engineering, Department of Biomedical Science, College of Life Science, CHA University, 618, CHA Biocomplex, Sampyeong-Dong, Bundang-gu, Seongnam-si, 13488, Republic of Korea.

For many years, researchers have sought to overcome major challenges in the use of nanoparticles as therapeutics, including issues related to intracellular delivery, biocompatibility, and activation. In particular, the genetic stability of cells treated with nanoparticles has become increasingly important in the context of stem cell therapy. Functional nanoparticles (Sunflower typed nanoparticles; SF-NPs) were fabricated by coating heparin pluronic F127 gels with quantum dot nanoparticles (QDs), and then bound the gene to the QD nanogels. Read More

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November 2018

MICAL2 Mediates p53 Ubiquitin Degradation through Oxidating p53 Methionine 40 and 160 and Promotes Colorectal Cancer Malignance.

Theranostics 2018 22;8(19):5289-5306. Epub 2018 Oct 22.

Department of Clinical Laboratory, Hunan Cancer Hospital & the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, 410013, Changsha, China.

Molecule interacting with CasL2 (MICAL2), a microtubule-associated monooxygenase, is highly expressed in various cancers and is involved in cancer pathogenesis, but the mechanisms underlying its regulation in carcinogenesis are unclear. In this study, we aim to clarify the mechanism by which MICAL2 participates in colorectal cancer (CRC) and identify novel markers for predicting prognosis of CRC patients. Methods: The value of MICAL2 in CRC prognosis was determined by immunohistochemical analysis of a CRC biopsy array. Read More

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October 2018

Photodynamic therapy at ultra-low NIR laser power and X-Ray imaging using CuBiS nanocrystals.

Theranostics 2018 21;8(19):5231-5245. Epub 2018 Oct 21.

Bio-Nano Electronics Research Centre, Toyo University, Kawagoe, 350-8585, Japan.

Materials with efficient potential in imaging as well as therapy are gaining particular attention in current medical research. Photodynamic therapy (PDT) has been recently recognized as a promising treatment option for solid tumors. Still, most of the nanomaterial-based PDT modules either employ an additional photosensitizer or require high power laser sources. Read More

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October 2018

Polydopamine-induced hydroxyapatite coating facilitates hydroxyapatite/polyamide 66 implant osteogenesis: an in vitro and in vivo evaluation.

Int J Nanomedicine 2018 30;13:8179-8193. Epub 2018 Nov 30.

Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China,

Background: Hydroxyapatite/polyamide 66 (HA/P66) has been clinically used for several years owing to its good biocompatibility and bioactivity. However, it has been found that the osseointegration process of the HA/P66 implant takes a large amount of time because of the small amount of HA on its surface.

Methods: To increase the amount of HA and aid faster osseointegration, we prepared a HA coating using a biomimetic process assisted by polydopamine (PDA) on the HA/P66 substrate. Read More

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November 2018

Retracted: Effects of Nano-Hydroxyapatite/Polyetheretherketone-Coated, Sandblasted, Large-Grit, and Acid-Etched Implants on Inflammatory Cytokines and Osseointegration in a Peri-Implantitis Model in Beagle Dogs.

Med Sci Monit 2018 Dec 5;24:8803. Epub 2018 Dec 5.

Department of Oral and Maxillofacial-Head and Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai, China (mainland).

ABSTRACT The article is withdrawn by the authors request. Read More

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December 2018

Ultrasound-assisted water-in-palm oil nano-emulsion: Influence of polyglycerol polyricinoleate and NaCl on its stability.

Ultrason Sonochem 2018 Dec 8. Epub 2018 Dec 8.

Graphene & Advanced 2D Materials Research Group (GAMRG), School of Science and Technology, Sunway University, No. 5, Jalan Universiti, Bandar Sunway, 47500 Subang Jaya, Selangor, Malaysia.

This study aimed to formulate a stable palm oil-based water-in-oil (W/O) nano-emulsion. Emphasis was placed on the effects of polyglycerol polyricinoleate (PGPR), medium chain triglyceride (MCT), lecithin and sodium chloride (NaCl) addition towards the stability of nano-emulsion. Among the performed analyses were mean droplet diameter (MDD), dispersity index (DI), critical micelle concentration (CMC), lipid peroxidation, viscosity, sedimentation index (SI) and surface morphology. Read More

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December 2018

Understanding the kinetic mixing between liquid crystalline nanoparticles and agrochemical actives.

Colloids Surf B Biointerfaces 2018 Nov 27;175:324-332. Epub 2018 Nov 27.

Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University (Parkville Campus), 381 Royal Parade Parkville, Victoria, 3052, Australia; ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, Monash Institute of Pharmaceutical Sciences, Monash University (Parkville Campus), 381 Royal Parade Parkville, Victoria, 3052, Australia. Electronic address:

The use of liquid crystalline nanoparticles as potential agrochemical delivery agents or adjuvant systems is gaining traction due to the possibility that the systems can enhance penetration of the active and increase adhesion of the formulation to the leaf, increasing overall efficacy and decreasing the harmful environmental impact. However the interaction between liquid crystalline nanoparticles and active products is not well understood. Using small angle X-ray scattering we investigated the structural changes that occur to liquid crystalline nanoparticles upon addition of three common herbicides, 2,4-D 2-ethylhexyl ester, bromoxynil octanoate and haloxyfop-p-methyl ester active agrochemicals in the form of emulsions. Read More

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November 2018

Repolarization of myeloid derived suppressor cells via magnetic nanoparticles to promote radiotherapy for glioma treatment.

Nanomedicine 2018 Dec 13. Epub 2018 Dec 13.

Northwestern University Feinberg School of Medicine, Chicago, IL, United States. Electronic address:

Although radiotherapy has been established as a major therapeutic modality for glioma, radical new avenues are critically needed to prevent inevitable tumor recurrence. Herein, we utilized a magnetic nanoparticle-based platform with cationic polymer modification to promote radiotherapy for glioma treatment. We found that the nanoplatform induced cytotoxicity to glioma cells under radiation as well as promoting significant survival benefits in both immunocompetent and aythmic mice with glioma. Read More

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December 2018
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Endoscopic Ultrasound-Guided Fine-Needle Injection of Hydrogen Peroxide into the Pancreas: Feasibility and Tolerability Study Using a Survival Porcine Model.

Ultrasound Med Biol 2018 Dec 12. Epub 2018 Dec 12.

Department of Radiology, Gifu University Graduate School of Medicine, Gifu, Japan.

Hydrogen peroxide (HO) has been reported to be an effective radiation sensitizer for various cancers. A combination therapy comprising fine-needle injection (FNI) of HO under endoscopic ultrasound (EUS) guidance and chemoradiation might improve treatment outcomes of pancreatic cancer; however, there have been no reports thus far. The aims of this study were to evaluate the feasibility and safety of EUS-FNI of HO into the pancreas using a porcine survival model. Read More

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December 2018

Magnetic chitosan nanocomposite: Fabrication, properties, and optimization for adsorptive removal of crystal violet from aqueous solutions.

Carbohydr Polym 2019 Feb 19;206:844-853. Epub 2018 Nov 19.

Department of Environmental Health Engineering, School of Health and Nutrition, Lorestan University of Medical Sciences, Khorramabad, Iran; Nutritional Health Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.

Recovery of crystal violet (CV) dye was investigated using magnetic chitosan nano-composites (MCNCs) and the effects of process variables (contact time, initial CV concentration, adsorbent dose, and pH) were optimized through response surface methodology. The reliability of the RSM models (first-order model, first model with interaction, the second-order model, and reduced model) was tested by fitting the data. A comparative analysis of the results derived from the models demonstrated that the reduced model was the best. Read More

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February 2019

Fabrication of innovative thermoplastic starch bio-elastomer to achieve high toughness poly(butylene succinate) composites.

Carbohydr Polym 2019 Feb 17;206:827-836. Epub 2018 Nov 17.

School of Mechanical and Automotive, South China University of Technology, Guangdong Guangzhou 510640, China.

Sustainable biodegradable polymers with high performances is the optimized alternatives for resolving environmental key issues evoked by petroleum-based polymer. A novel bio-based elastomer was designed and developed using reactive extrusion for the mixtures of starch, glycerol and tartaric acid (TPS-TA). Then TPS-TA was extruded with PBS (30:70, wt%) to fabricate the bio-composites and the impact strength of PBS/TPS-TA was superior to that of PBS. Read More

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February 2019

In vitro permeability enhancement of curcumin across Caco-2 cells monolayers using electrospun xanthan-chitosan nanofibers.

Carbohydr Polym 2019 Feb 29;206:38-47. Epub 2018 Oct 29.

Nano-BioScience Research Group, DTU-Food, Technical University of Denmark, Kemitorvet, B202, 2800 Kgs. Lyngby, Denmark. Electronic address:

Xanthan-Chitosan (X-Ch) polysaccharides nanofibers were prepared using electrospinning processing as an encapsulation and delivery system of curcumin (Cu). The X-Ch-Cu nanofibers remained stable in aqueous HBSS medium at pH 6.5 and pH 7. Read More

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February 2019

Eco-friendly modification of a regenerated cellulose based film by silicon, carbon and N-doped carbon quantum dots.

Carbohydr Polym 2019 Feb 29;206:238-244. Epub 2018 Oct 29.

Grupo de Caracterización Electrocinética en Membranas e Interfases, Dpto. Física Aplicada I, Facultad de Ciencias, Universidad de Málaga, 29071 Málaga, Spain. Electronic address:

Modification of a regenerated cellulose thin film by inclusion of different non-toxic nanodots (silicon-dots (SiDs), carbon-dots (CDs)) or nitrogen-doped carbon dots (N-CDs)) by aqueous nanodots solution immersion was performed. Nanodots presence into the cellulosic structure was evidenced by confocal microscopy images at different depth and changes in film mechanical, electrical and optical parameters. Our results reveal that the inclusion of the different nanodots in the cellulosic support increases, indifferent percentages, the mechanical resistance and electrical conductivity of modified films, but they hardly affect light transmittance. Read More

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February 2019

Structural characterization of cellulose pulp in aqueous NMMO solution under the process conditions of lyocell slurry.

Carbohydr Polym 2019 Feb 5;206:220-228. Epub 2018 Nov 5.

National Centre for Nanosciences and Nanotechnology, University of Mumbai, Kalina Campus, Kalina, Santacruz (E), Mumbai 400098, India. Electronic address:

A systematic structural characterization of dissolving grade cellulose pulp in aqueous NMMO solution is performed under the process conditions of lyocell slurry. Different types of cellulosic pulps such as hard/soft wood and acid sulfite/kraft sulphate pulps are used for the present study. The structural changes of pulp in lyocell slurry at different temperatures are characterized in terms of dimension, interstitial spaces, crystallinity using Optical (weight and thickness gain), SEM and XRD measurement technique, respectively. Read More

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February 2019

Rheological properties of super critical CO with CuO: Multi-scale computational modeling.

J Chem Phys 2018 Dec;149(22):224702

Department of Mechanical and Industrial Engineering, NTNU, Trondheim, Norway.

A multi-scale computational methodology based on the density functional theory and molecular dynamics has been used to investigate the rheological properties of super critical CO with CuO nano-particle (NP). Density functional theory which treats the electron density as the central variable has been used to explore the adsorption of CO molecules on the two most stable CuO surfaces [i.e. Read More

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December 2018

Stored potential energy increases and elastic properties alterations are produced after restoring dentin with Zn-containing amalgams.

J Mech Behav Biomed Mater 2018 Dec 6;91:109-121. Epub 2018 Dec 6.

University of Granada, Faculty of Dentistry, Dental Materials Section, Colegio Máximo de Cartuja s/n, 18071 Granada, Spain.

The aim of this research was to ascertain the mechanical and chemical behavior of sound and caries-affected dentin (CAD), after the placement of Zn-free vs containing amalgam restorations. Peritubular and intertubular dentin were evaluated using, a) nanoindenter in scanning mode; the load and displacement responses were used to perform the nano-Dynamic mechanical analysis and to estimate the complex (E * ) and storage modulus (E'); b) Raman spectroscopy was used to describe the hierarchical cluster analysis (HCA). Assessments were performed before restoration placement and after restoring, and after 3 months of storage with thermocycling (100,000cy/5 °C and 55 °C). Read More

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December 2018
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Effects of foliar application of zinc sulfate and zinc nanoparticles in coffee (Coffea arabica L.) plants.

Plant Physiol Biochem 2018 Dec 10;135:160-166. Epub 2018 Dec 10.

Department of Horticultural Sciences and Center for Coffee Research & Education, Texas A&M University, TAMU 2133, College Station, TX, 77843, USA.

A greenhouse study comparing the physiological responses and uptake of coffee (Coffea arabica L.) plants to foliar applications of zinc sulfate (ZnSO) and zinc nano-fertilizer (ZnO NPs) was conducted with the aim to understand their effects on plant physiology. One-year old coffee plants were grown in greenhouse conditions and treated with two foliar applications of 10 mg/L of Zn as either zinc sulfate monohydrate (ZnSO ‧ HO) or zinc oxide nanoparticle (ZnO NPs 20% w/t) and compared to untreated control plants over the course of 45 days. Read More

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December 2018
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Energy and cost-efficient nano-Ru-based perovskites/RGO composites for application in high performance supercapacitors.

J Colloid Interface Sci 2018 Dec 5;538:578-586. Epub 2018 Dec 5.

Institute of Electrochemistry, Ulm University, 89081 Ulm, Germany; Helmholtz-Institute-Ulm (HIU) [d], Helmholtzstr. 11, 89081 Ulm, Germany; Karlsruhe Institute of Technology (KIT), P.O. Box 3640, 76021 Karlsruhe, Germany. Electronic address:

Nano-Ru-based perovskites RGO are prepared simultaneously in presence of various A-metal salts (A = Sr, Ba or Ca salts) using two different methods for reaction initiation. No further calcination step is needed for the formation of well-defined perovskite structure. Graphene oxide (GO) is used as a fuel to prepare various Ru-based perovskites for the first time. Read More

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December 2018
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Enhancement of the apparent solubility and bioavailability of Tadalafil nanoparticles via antisolvent precipitation.

Eur J Pharm Sci 2018 Dec 12. Epub 2018 Dec 12.

School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, PR China. Electronic address:

The ability to increase the bioavailability and dissolution of poorly soluble hydrophobic drugs has been a major challenge for pharmaceutical development. This study shows that the dissolution rate, apparent solubility and oral bioavailability of tadalafil (Td) can be improved by nano-sized amorphous particles prepared by using antisolvent precipitation. Acetone and an acetone-water solution (v:v, 9:1) were selected as solvents, with deionized water as the antisolvent. Read More

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December 2018
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Nano-based smart pesticide formulations: Emerging opportunities for agriculture.

J Control Release 2018 Dec 12. Epub 2018 Dec 12.

Department of Civil & Environmental Engineering, Hanyang University, 222 Wangsimni-Ro, Seoul 04763, Republic of Korea. Electronic address:

The incorporation of nanotechnology as a means for nanopesticides is in the early stage of development. The main idea behind this incorporation is to lower the indiscriminate use of conventional pesticides to be in line with safe environmental applications. Nanoencapsulated pesticides can provide controlled release kinetics, while efficiently enhancing permeability, stability, and solubility. Read More

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December 2018
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In vitro anti-inflammatory and antioxidant potential of thymol loaded bipolymeric (tragacanth gum/chitosan) nanocarrier.

Int J Biol Macromol 2018 Dec 12. Epub 2018 Dec 12.

Department of Bio & Nano Technology, Guru Jambheshwar University of Science & Technology, Hisar, Haryana 125001, India. Electronic address:

Thymol is a natural bioactive agent which possesses various medicinal properties like antimicrobial, antifungal, anti-inflammatory, anticancer etc. and has been widely used in traditional medicine and food industries. It is eco-friendly, cheaper, nontoxic and has been granted generally recognized as safe (GRAS) notation by USFDA. Read More

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December 2018
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F-doped TiO microporous coating on titanium with enhanced antibacterial and osteogenic activities.

Sci Rep 2018 Dec 14;8(1):17858. Epub 2018 Dec 14.

State Key Laboratory for Mechanical Behavior of Materials, Xi'an Jiaotong University, Xi'an, 710049, China.

To enhance bacterial resistance and osteogenesis of titanium (Ti) -based implants, TiO/calcium-phosphate coatings (TiCP) doped with various amounts of fluorine (F) (designated as TiCP-F1, TiCP-F6, and TiCP-F9) were prepared on Ti by micro-arc oxidation. The F doped TiCP coatings possess a microporous structure (pore size of 3-4 μm in average diameter) which is evenly covered by nano-grains of 30-60 nm in size. Successful F incorporation into TiCP was determined by X-ray photoelectron spectroscopy, and it shows weak influence on the microstructure, phase compositions, surface roughness and wettability of TiCP. Read More

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December 2018
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