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    Rate of Subtalar Joint Arthrodesis After Retrograde Tibiotalocalcaneal Arthrodesis With Intramedullary Nail Fixation: Evaluation of the RAIN Database.
    Foot Ankle Spec 2017 Nov 1:1938640017740674. Epub 2017 Nov 1.
    Washington Orthopaedic Center, Centralia, Washington (MD).
    Background: Hindfoot arthritis or significant deformity involving the ankle and subtalar joint (STJ) is a disabling condition with few salvage options. Many surgeons note a decreased STJ fusion rate compared with ankle union when a retrograde nail construct is used. The purpose of this study was to report the STJ fusion rate of tibiotalocalcaneal (TTC) arthrodesis with retrograde nail. Read More

    Application of 3D technology and printing for femoral derotation osteotomy: case and technical report.
    Ann Transl Med 2017 Oct;5(20):400
    Arthroscopy Surgery Unit, Hospital Vithas San José, Vitoria-Gasteiz, Spain.
    In some surgical techniques like femoral derotation osteotomy, accuracy is a key factor that often is not optimal because of the lack of appropriate technology. 3D printing is emerging in many professional areas and its use in the medical field may enhance the results of certain surgeries. This case describes a patient who underwent an intramedullary nail fixation to treat a femoral shaft fracture. Read More

    Late postoperative analysis of the tip-apex distance (TAD) in pertrochanteric fractures: is there an accommodation of the implant within the bone?
    Injury 2017 Oct;48 Suppl 4:S54-S56
    Irmandade da Santa Casa de Misericóridia de São Paulo, São Paulo, Brazil.
    Introduction: This study measured the tip-apex distance (TAD) values in the immediate postoperative period and following weight-bearing and fracture impaction in patients undergoing osteosynthesis with dynamic hip screw and cephalomedullary nail.

    Objective: To correlate the Baumgaertner index in the immediate postoperative period with values obtained after impaction of the fracture with the accommodation of the cephalic implant in the femoral head.

    Patients And Methods: Radiographic TAD measurements were taken with AGFA-VIEW(®) of 82 patients with a mean age of 72 years with pertrochanteric fractures who were operated on and the fracture fixed with DHS- Synthes(®), TFN-Synthes(®), or Gamma Nail III-Stryker(®) in the immediate postoperative period, and following weight-bearing and fracture impaction (mean 3-8 weeks after surgery). Read More

    Pathologic femoral fracture due to tenofovir-induced Fanconi syndrome in patient with chronic hepatitis B: A case report.
    Medicine (Baltimore) 2017 Nov;96(46):e8760
    aCenter of Arthroplasty bDepartment of Orthopaedic Surgery cDepartment of Nephrology, Soonchunhyang University Hospital Seoul, Seoul dDepartment of Orthopaedic Surgery, Chuncheon Sacred Heart Hospital, Hallym University, Chuncheon-si, Gangwon-do, Korea.
    Rationale: We report a case of a hepatitis B virus (HBV)-positive patient with preexisting bone disease who developed tenofovir-induced Fanconi syndrome and subsequently sustained pathologic fracture. To our best knowledge, this is the first report in the English literature about pathologic femoral fracture due to tenofovir-induced Fanconi syndrome in patient with chronic hepatitis B (CHB). The present report describes detailed our experience with the diagnosis of pathologic femoral fracture due to tenofovir-induced Fanconi syndrome and treatment. Read More

    Diphthamide Biosynthesis 1 is a Novel Oncogene in Colorectal Cancer Cells and is Regulated by MiR-218-5p.
    Cell Physiol Biochem 2017 Nov 17;44(2):505-514. Epub 2017 Nov 17.
    State Key Laboratory of Pharmaceutical Biotechnology, Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, NJU Advanced Institute for Life Sciences (NAILS), School of Life Sciences, Nanjing University, Nanjing, China.
    Background/aims: This study focused on the oncogenic role of Diphthamide biosynthesis 1 (DPH1) in colorectal cancer (CRC) cells.

    Methods: The expression of DPH1 was determined by quantitative RT-PCR analysis and western blotting in CRC tissues. The role of DPH1 in CRC cells was investigated via cell viability and invasion assays under the condition of DPH1 silencing or overexpression. Read More

    A Real-World Retrospective Cohort Study of Combined Therapy with Bevacizumab and Paclitaxel in Japanese Patients with Metastatic Breast Cancer.
    J Nippon Med Sch 2017 ;84(5):215-223
    The Saitama Breast Cancer Clinical Study Group.
    Objective: Combined therapy with bevacizumab and paclitaxel (BP regimen) as a first-line treatment has proven highly effective with good tolerance for patients with metastatic breast cancer (MBC). The objective of this study was to examine the efficacy and safety of the BP regimen for Japanese patients with MBC in real-world clinical settings.

    Methods: From June 2012 through May 2014, we recruited 94 patients at 10 medical institutions. Read More

    Clinical outcome of dynamic hip locking plates and proximal femoral nails anti-rotation-Asia for treating intertrochanteric femur fracture with lateral wall fractures in the elder patients.
    Oncotarget 2017 Oct 31;8(47):82700-82704. Epub 2017 Jul 31.
    Department of Orthopaedics, Jiaxing No. 2 Hospital, Jiaxing University, Jiaxing 314001, China.
    Purpose: To compare the clinical results of DHLP (Dynamic hip locking plates) and PFNA-IIs (proximal femoral nails anti-rotation-Asia) for treating intertrochanteric femur fracture (IFF) with lateral wall fractures in the elder patients and provide a rationale for the clinical practice.

    Methods: A retrospective analysis of 43 patients of IFF with lateral wall fractures was performed from December 2009 to April 2015. Intraoperative variables and postoperative complications and function were compared between the two groups. Read More

    Effect of Locking Plate Fixation vs Intramedullary Nail Fixation on 6-Month Disability Among Adults With Displaced Fracture of the Distal Tibia: The UK FixDT Randomized Clinical Trial.
    JAMA 2017 11;318(18):1767-1776
    Statistics and Epidemiology Unit, University of Warwick Medical School, Coventry, United Kingdom.
    Importance: The best treatment for fractures of the distal tibia remains controversial. Most such fractures require surgical fixation but outcomes are unpredictable and complications are common.

    Objective: To assess disability, quality of life, and complications in patients with displaced tibial fracture treated with intramedullary nail fixation vs locking plate fixation. Read More

    [Protective measures in laparoscopic resection for upper or mid rectal cancer and sigmoid colon cancer with transrectal specimen extraction surgery].
    Zhonghua Wei Chang Wai Ke Za Zhi 2017 Oct;20(10):1151-1155
    Department of Colorectal Surgery, The Affiliated Shanghai East Hospital, Tongji University, Shanghai 200120, China.
    Objective: To introduce the use of a self-made specimen protective sleeve in laparoscopic resection for upper or mid rectal cancer and sigmoid colon cancer with transrectal specimen extraction surgery and the improvement of implantation method, so as to avoid and reduce bacterial contamination and tumor cell dissemination in abdominal cavity.

    Methods: During June 2015 and May 2017, 48 cases of high located rectal or sigmoid colon cancer were operated laparoscopically with natural orifices specimen extraction surgery (NOSES) using a self-made specimen protecting sleeve. Operation indication: (1) Rectum and sigmoid colon cancer with the distance of more than 6 cm from tumor inferior margin to dentate line. Read More

    A Comparison of the Device-Related Complications of Intramedullary Lengthening Nails Using a New Classification System.
    Biomed Res Int 2017 9;2017:8032510. Epub 2017 Oct 9.
    Division of Orthopaedic Surgery, Severance Children's Hospital, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea.
    The purpose of this study was to understand the pros and cons of the lengthening nails which have their own mechanical mechanism; we propose a classification for "device-related complications" arising from mechanical properties of the nail itself. From March 2010 to March 2014, 115 segments of lower limb lengthening were performed using intramedullary lengthening nails (35 ISKD, 34 PRECICE1, and 46 PRECICE2). Device-related complications were sorted into three categories according to a new classification: distraction control-related (type I), stability related (type II), and other device-related (type III); these were subdivided using Paley's concept of problems (a), obstacles (b), and sequel (c). Read More

    Hypoxia-induced miR-214 expression promotes tumour cell proliferation and migration by enhancing the Warburg effect in gastric carcinoma cells.
    Cancer Lett 2017 Nov 10;414:44-56. Epub 2017 Nov 10.
    Department of Gastroenterology, Drum Tower Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210008, China. Electronic address:
    miR-214 is an important oncomiRNA and is upregulated in various types of cancer, including gastric cancer. However, the molecular mechanism underlying the ectopic expression and function of miR-214 in gastric cancer is largely undefined. In this study, we found that miR-214 induces the Warburg effect and promotes the migration and proliferation of human gastric cancer cells. Read More

    Tibiotalocalcaneal Arthrodesis With the Hindfoot Arthrodesis Nail: A Prospective Consecutive Series From a Single Institution.
    J Foot Ankle Surg 2017 Nov 9. Epub 2017 Nov 9.
    Consultant, Department of Orthopaedic Surgery, Tan Tock Seng Hospital, Singapore.
    Tibiotalocalcaneal arthrodesis (TTCA) is a salvage procedure. We report a series of 20 patients who underwent TTCA using an intramedullary nail. Of the 20 patients, 7 (35%) had diabetes mellitus. Read More

    Carbon-Fibre-Reinforced PEEK radiolucent intramedullary nail for humeral shaft fracture fixation: technical features and a pilot clinical study.
    Injury 2017 Nov;48 Suppl 5:S8-S11
    Trauma and Orthopaedics Department, Brighton and Sussex University Hospitals, NHS Trust, United Kingdom.
    Purpose: This prospective pilot study investigated the safety and efficacy of a novel radiolucent intramedullary nail (IMN) made of Carbon-Fibre-Reinforced Polyaryl-Ether-Ether-Ketone (CFR-PEEK) for humeral shaft fracture fixation.

    Study Design: A prospective, single-arm, four-centre study.

    Patients And Methods: A total of 46 patients with 46 humeral fractures classified as 12 A-B were treated with a novel CFR-PEEK IMN and followed for 12 months. Read More

    Outcome of Hook Plate Fixation of Mallet Fractures.
    J Hand Surg Asian Pac Vol 2017 Dec;22(4):416-422
    1 Department of Hand Surgery, Singapore General Hospital, Singapore.
    Background: Hook plate fixation of closed mallet fractures was first described in 2007, but there has subsequently been a lack of studies examining the outcomes and complications of this technique.

    Methods: This paper aims to assess the clinical outcomes of hook plate fixation of closed mallet fractures by retrospectively reviewing 31 closed, bony mallet injuries that were surgically fixed with a hook plate between 2002-2011.

    Results: Patients who underwent hook plate fixation had a median time to radiographic union of 83 days. Read More

    Paronychia with Sporangium Formation Causing an Ingrown Toenail A Rare Case Report.
    J Am Podiatr Med Assoc 2017 Nov 8. Epub 2017 Nov 8.
    § Shuang-Ho Hospital, Taipei Medical University, Taipei, Taiwan Division of Plastic Surgery, Department of Surgery.
    Ingrown toenail, or onychocryptosis, is a common inflammatory disease of the hallux. It results from the alteration of fit of the nail plate in the lateral nail fold. They are usually seen in adolescents and young adults and can affect daily activities and social life. Read More

    Missed opportunity to diagnose subungual melanoma: potential pitfalls!
    BMJ Case Rep 2017 Nov 3;2017. Epub 2017 Nov 3.
    Department of Plastic Surgery, John Radcliffe Hospital, Oxford, UK.
    Subungual melanoma, an uncommon form of acral melanoma that arises within the nail matrix, accounts for 1%-3% of all cutaneous melanoma in Caucasians. As subungual melanoma presents in a more disguised manner than cutaneous lesions, increased vigilance is required. It most commonly presents as a discolouration of the nail, nail splitting or nail-bed bleeding. Read More

    Sliding hip screw versus intramedullary nail for trochanteric hip fractures; a randomised trial of 1000 patients with presentation of results related to fracture stability.
    Injury 2017 Oct 20. Epub 2017 Oct 20.
    Department of Orthopaedics, Peterborough City Hospital, Peterborough and Stamford Hospital NHS Foundation Trust, Bretton Gate, Peterborough PE3 9GZ, England, United Kingdom. Electronic address:
    Aims: To determine the optimum choice of implant for a patient with a the different types of trochanteric hip fracture.

    Patients And Methods: 1000 patients with a trochanteric hip fracture were randomised to internal fixation of the fracture with either a Sliding Hip Screw or an intramedullary nail. Fractures were subdivided into two part fractures, comminuted fractures and fractures at the level of the lesser trochanter (reversed/oblique and transverse). Read More

    Evaluation of Complications from Stainless-Steel Flexible Intramedullary Nailing in Children's Femoral Shaft Fractures and Recommendations for Continued Use.
    Ortop Traumatol Rehabil 2017 May;19(3):263-271
    Government Hospital for Bone and Joint Surgery, Barzulla, Srinagar, Kashmir.
    [b]Background.[/b] Flexible intramedullary nailing is currently considered the treatment of choice for femoral diaphyseal fractures in school-aged children. The purpose of our study was to critically evaluate and analyze the complications of stainless steel flexible intramedullary nailing in children's femoral shaft fractures. Read More

    Digital Assessment of the Implantation Angle of Proximal Femoral Nail Antirotation Helical Blade Using CT Three-dimensional Reconstruction.
    J Invest Surg 2017 Oct 30:1-7. Epub 2017 Oct 30.
    c Department of Physical diagnostics section, Rehabilitation Branch of Seafarers General Hospital of Heilongjiang province , Harbin , China.
    Objectives: To facilitate simple and safe manipulation during proximal femoral nail antirotation (PFNA) operation, we studied the range of safe implantation angle of the helical blade of the PFNA system by using a digital-based three-dimensional reconstruction model of CT images.

    Methods: Thirty-five healthy volunteers were recruited. Original multilayer helical CT scan data of the left femur were collected and imported into Mimics software. Read More

    Role of Extra-articular Tibiotalocalcaneal Arthrodesis and Posterior Approach in Highly Complex Cases.
    Foot Ankle Int 2017 Oct 1:1071100717737973. Epub 2017 Oct 1.
    2 Department of Orthopaedic Surgery & Traumatology, Hospital Clínic, Barcelona, España.
    Background: Tibiotalocalcaneal (TTC) arthrodesis is a procedure commonly used as salvage surgery for various pathologic processes that compromise the ankle and subtalar joints. It is a reasonably standardized procedure when performed as a primary surgery in advanced stages of TTC arthritis. For such cases, there are several alternative approaches, fixation materials, and bone substitutes that can be used. Read More

    Role of Surgery in Management of Osteo-Articular Tuberculosis of the Foot and Ankle.
    Open Orthop J 2017 31;11:633-650. Epub 2017 Jul 31.
    Director and Head of Orthopedics, Noble Hospital, Pune, Maharashtra, India.
    Background: Tuberculosis of the foot and ankle still remains to be a significant problem, especially in the developing countries, and with an increase in incidence in immunosuppressed patients. Treatment is mainly medical using multidrug chemotherapy; surgical interventions range from biopsy, synovectomy and debridement, to joint preserving procedures like distraction in early cases, and arthrodesis of hindfoot joints and the ankle in advanced disease with joint destruction. Surgical Options: All procedures should be done after initiating appropriate medical management. Read More

    The course of the radial nerve in the distal humerus: A novel, anatomy based, radiographic assessment.
    PLoS One 2017 26;12(10):e0186890. Epub 2017 Oct 26.
    Department of Neuroscience-Anatomy and Erasmus MC Anatomy Research Project (EARP), Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
    Methods And Findings: Measurements were done on both arms of ten specially embalmed specimens. Arms were dissected and radiopaque wires attached to the radial nerve in the distal part of the upper arm. Digital radiographs were obtained to determine the course of the radial nerve in the distal 20 cm of the humerus in relation to bony landmarks; medial epicondyle and capitellum-trochlea projection (CCT). Read More

    Novel Passive Two-Stage Magnetic Targeting Devices for Distal Locking of Interlocking Nails.
    J Healthc Eng 2017 13;2017:3619403. Epub 2017 Aug 13.
    Department of Biological Science and Technology, National Chiao Tung University, Hsinchu 30010, Taiwan.
    Interlocking nailing is a common surgical operation to stabilize fractures in long bones. One of the difficult parts of the surgery is how to locate the position and direction of a screw hole on the interlocking nail, which is invisible to the naked eye after insertion of the nail into the medullary canal. Here, we propose a novel two-stage targeting process using two passive magnetic devices to locate the position and direction of the screw hole without radiation for the locking screw procedure. Read More

    [RARE LOCALIZATION OF OSTEOID OSTEOMA--DISTAL PHALANX OF THE RING FINGER].
    Acta Med Croatica 2016 09;70(3):191-5
    With this clinical observation we would like to bring to mind osteoid osteoma as a possible cause of problems of distal phalanx of the fingers. Osteoid osteoma occurs rarely at this location and has atypical presentation. The main symptoms are swelling and redness of the fingertip with nail deformity, while typical night pain may not be present. Read More

    Outcomes of fracture shaft femur in pediatric population managed at emergency.
    J Clin Orthop Trauma 2017 Oct-Dec;8(4):313-319. Epub 2016 Dec 15.
    Department of Orthopaedic Surgery, King George's Medical University, Lucknow, Uttar Pradesh 226018, India.
    Background: Fracture shaft of femur is amongst one of the commonest major diaphyseal injuries in school going children presenting to us at emergency rooms of our hospitals. The presence of a growing proximal and distal physes imposes a real challenge in management of these fractures. The use of titanium elastic nails has gained wide acceptance for stabilizing these fractures. Read More

    Characterization of serum miRNAs as molecular biomarkers for acute Stanford type A aortic dissection diagnosis.
    Sci Rep 2017 Oct 20;7(1):13659. Epub 2017 Oct 20.
    State Key Laboratory of Pharmaceutical Biotechnology, Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, NJU Advanced Institute for Life Sciences (NAILS), School of life sciences, Nanjing University, 163 Xianlin Road, Nanjing, 210046, China.
    Early and convenient diagnosis is urgently needed for acute Stanford type A aortic dissection (AAAD) patients due to its high mortality within the first 48 hours. Circulating microRNAs (miRNAs) are promising biomarkers of cardiovascular diseases, however, little is known about circulating miRNAs involved in AAAD. Here, the blood serum was sampled from 104 AAAD+ patients and 103 age-matched donors. Read More

    Humeral shaft fractures: union outcomes in a large cohort.
    J Shoulder Elbow Surg 2017 Nov;26(11):1881-1888
    Department of Surgery, Peninsula Health, Frankston, VIC, Australia. Electronic address:
    Background: Humeral shaft fractures can be managed conservatively or operatively. Fracture characteristics were analyzed to identify patients who would benefit from early operative fixation.

    Methods: We performed a retrospective cohort study of 126 consecutive humeral shaft fractures (2008-2015). Read More

    The Community Orthopaedic Surgeon Taking Trauma Call: Pediatric Femoral Shaft Fracture Pearls and Pitfalls.
    J Orthop Trauma 2017 Nov;31 Suppl 6:S16-S21
    *Pediatric Orthopedic Surgery, St Louis Children's Hospital, Washington University School of Medicine, St Louis, MO; and †Division of Pediatric Orthopaedic Surgery, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH.
    Pediatric femoral shaft fractures present many challenging patient care decisions. Nonoperative treatment approaches still dominate care of the youngest age groups while surgical intervention is commonplace in virtually all older children. Treatment is determined primarily by patient age as modified by clinical factors including mechanism of injury, weight, and skeletal maturity. Read More

    Randomized feasibility trial of replacing or discarding the nail plate after nail-bed repair in children.
    Br J Surg 2017 Nov;104(12):1634-1639
    Department of Plastic Surgery, Imperial College Healthcare NHS Trust, London, UK.
    Background: Nail-bed injuries are the most common hand injury in children. Surgical dogma is to replace the nail plate after repairing the nail bed. Recent evidence suggests this might increase infection rates and returns to clinic. Read More

    Fatigue failure of the cephalomedullary nail: revision options, outcomes and review of the literature.
    Eur J Orthop Surg Traumatol 2017 Oct 17. Epub 2017 Oct 17.
    Altnagelvin Area Hospital, Glenshane Road, Londonderry, BT47 6SB, Northern Ireland, UK.
    Cephalomedullary nail (CMN) failure is a rare entity following hip fracture treatment. However, it poses significant challenges for revision surgery, both mechanically and biologically. Nail failure rates have been reported at < 2%; however, no published studies have reported revision surgery procedures and their respective outcomes. Read More

    Application of 3D printing rapid prototyping-assisted percutaneous fixation in the treatment of intertrochanteric fracture.
    Exp Ther Med 2017 Oct 22;14(4):3644-3650. Epub 2017 Aug 22.
    Department of Orthopedic Surgery, Nanjing Medical University, Nanjing Hospital, Nanjing, Jiangsu 210006, P.R. China.
    The aim of the present study was to investigate the application of 3D printing (3DP) rapid prototyping (RP) technique-assisted percutaneous fixation in the treatment of femoral intertrochanteric fracture (ITF) using proximal femoral nail anti-rotation (PFNA). A total of 39 patients with unstable ITF were included in the current study. Patients were divided into two groups: 19 patients were examined using computed tomography scanning and underwent PFNA with SDP-RP whereas the other 20 patients underwent conventional PFNA treatment. Read More

    Multiple glomus tumours in multidigit nail bed.
    Handchir Mikrochir Plast Chir 2017 Oct 17;49(5):321-325. Epub 2017 Oct 17.
    Bundang CHA Medical Center, Department of Orthopaedic Surgery.
    Glomus tumours are lesions of the glomus body. A solitary glomus tumour is a more common, characteristically painful lesion, frequently located under the nail, whereas multiple glomus tumours are a rare clinical and genetic entity. Multiple glomus tumours are rarely subungual and do not show preference for any particular region of the body. Read More

    Preventing wedge deformities when treating intertrochanteric femur fractures with intramedullary devices: A technical tip.
    J Orthop Trauma 2017 Oct 7. Epub 2017 Oct 7.
    1Northwestern Memorial Hospital - Department of Orthopedic Surgery, 676 North St. Clair St., Suite 1350, Chicago, Illinois, 60661, USA 2Loyola University Chicago Department of Orthopaedic Surgery and Rehabilitation, 2160 S First Ave, Maywood, IL 60153.
    Intertrochanteric femur fractures are common injuries associated with significant patient morbidity and mortality and high societal costs. Although intramedullary devices have shown promise for treating a wide range of intertrochanteric femur fractures, improper technique can lead to malalignment, fracture displacement and/or iatrogenic fractures. In particular, a "wedge effect" has been described, in which the passage of conical reamers and the intramedullary nail itself results in distraction of intertrochanteric fragments with lateralization of the shaft from the femoral neck and varus malalignment. Read More

    Distal femoral flexion deformity from growth disturbance treated with a two-level osteotomy and internal lengthening nail.
    Strategies Trauma Limb Reconstr 2017 Nov 16;12(3):159-167. Epub 2017 Oct 16.
    Hospital for Special Surgery, 535 East 70th Street, New York, NY, 10021, USA.
    Salter Harris fractures of the distal femur can lead to growth disturbance with resulting leg length inequality and knee deformity. We have looked at a case series (3) of patients who presented with a distal femur flexion malunion and shortening treated with a distal femoral osteotomy and plating and a proximal femoral osteotomy with a magnetic internal lengthening nail. Does a two-level osteotomy and internal fixation approach provide a reliable result both radiographically and functionally? The average knee extension loss was 12°, LLD 47 mm, PDFA 65°, MAD 2 mm. Read More

    Hybrid Fixation for Ankle Fusion in Diabetic Charcot Arthropathy.
    Foot Ankle Int 2017 Oct 1:1071100717735074. Epub 2017 Oct 1.
    1 Department of Orthopedic Surgery, Faculty of Medicine, Mansoura University, Mansoura, Eldakahlia, Egypt.
    Background: Ankle fusion is difficult to achieve in the diabetic Charcot ankle Brodsky type 3a because of the poor quality of the bone and the inability to achieve a stable biomechanical construct. The aim of this study was to report the outcome of ankle fusion using a combination of an intramedullary nail and a circular external fixator in patients with diabetic Charcot arthropathy.

    Methods: We prospectively studied 24 patients with diabetic Charcot arthropathy of the ankle who were treated by fusion of the tibiotalar joint using a combined retrograde intramedullary nail and Ilizarov external fixator. Read More

    Carbon-fiber reinforced intramedullary nailing in musculoskeletal tumor surgery: a national multicentric experience of the Italian Orthopaedic Society (SIOT) Bone Metastasis Study Group.
    Injury 2017 Oct;48 Suppl 3:S55-S59
    The Italian Orthopaedic Society (SIOT), Rome, Italy.
    Introduction: Carbon fiber reinforced (CFR) implants have been proposed for the treatment of fractures or impending fractures of the long bones in the oncology patient. Aim of this study is to present the largest cohort of oncology patients operated by CFR nailing by the Italian Orthopaedic Society (SIOT) Bone Metastasis Study Group.

    Methods: 53 adult oncology patients were operated on with a CFR-PEEK nail. Read More

    Blood loss in trochanteric fractures: multivariate analysis comparing dynamic hip screw and Gamma nail.
    Injury 2017 Oct;48 Suppl 3:S44-S47
    Orthopaedics and Traumatology, Department of Biotechnology and Life Sciences (DBSV), University of Insubria, Varese, Italy.
    Introduction: Anaemia in patients with trochanteric fracture is associated with increased morbidity and mortality and it is an independent risk factor for functional mobility of patients. Several authors have reported the blood loss following operative treatment comparing different fixation systems but few authors have evaluated many associated variables that could influence the perioperative blood loss.

    Purpose: To evaluate the blood loss in patients that had their trochanteric fracture stabilized with dynamic hip screw (DHS) or Gamma nail. Read More

    A systematic review of cost-effectiveness, comparing traction to intramedullary nailing of femoral shaft fractures, in the less economically developed context.
    BMJ Glob Health 2017 25;2(3):e000313. Epub 2017 Sep 25.
    Department of Orthopaedics, Beit CURE International Malawi, Blantyre, Malawi.
    Introduction: Femoral shaft fractures carry considerable morbidity and are increasingly common in less economically developed countries (LEDCs). Treatment options include traction and intramedullary (IM) nailing but in a limited-resource environment; cost-effectiveness is fundamental to policy development. The objective herein was to evaluate the cost-effectiveness of moving from traction to IM nailing for femoral shaft fractures, in adults, in LEDCs. Read More

    A retrospective analysis of the InterTan nail and proximal femoral nail anti-rotation in the treatment of intertrochanteric fractures in elderly patients with osteoporosis: a minimum follow-up of 3 years.
    J Orthop Surg Res 2017 Oct 10;12(1):147. Epub 2017 Oct 10.
    Department of Orthopaedics, Jinshan Hospital, Fudan University, Longhang Road No. 1508, Jinshan District, Shanghai City, 201508, China.
    Background: The study aims to compare the long-term functional and radiographic outcomes of two devices for the treatment of primary intertrochanteric fractures (IFs, OTA 3.1A2.1-A2. Read More

    Motor-sparing continuous median nerve block for hand surgery: A pediatric case.
    Asian J Anesthesiol 2017 Sep 22. Epub 2017 Sep 22.
    Department of Anesthesia, Kitami Red Cross Hospital, Kitami, 090-0026, Japan. Electronic address:
    Here is described a successful perioperative pain control with continuous median nerve block after flexor tendon repair surgery on 2nd finger of a child. A 9-year-old patient was admitted for reconstruction surgery. The combination of median nerve block and lateral/medial antecubital cutaneous nerve blocks were performed before the surgery to cover all the surgical incision including the 2nd finger, palm, the graft site proximal to the wrist, and Kleinert traction at the nail bed. Read More

    "Kissing Nail Technique" for the exchange of intramedullary implants in adjacent peri-implant fractures.
    Acta Orthop Traumatol Turc 2017 Oct 3. Epub 2017 Oct 3.
    Department of Surgery, Ludwig-Maximilians-University, Campus Innenstadt, Munich, Germany. Electronic address:
    One third of the people aged 65 years and over fall every year, and 1-5% of these falls result in a fracture. For these people, history of fracture and surgery become a risk factor for recurrent falls. In osteoporotic patients, repeated fractures often require several osteosynthetic procedures within a short time frame. Read More

    Humeral Lengthening with the PRECICE Magnetic Lengthening Nail.
    HSS J 2017 Oct 21;13(3):217-223. Epub 2017 Apr 21.
    International Center for Limb Lengthening,Rubin Institute for Advanced Orthopedics,, Sinai Hospital of Baltimore, 2401 West Belvedere Avenue, Baltimore, MD 21215 USA.
    Background: Different types of external fixators have been used for humeral lengthening with successful outcomes reported in literature. Motorized intramedullary (IM) lengthening nails have been developed as an alternative to external fixators for long bone lengthening in the lower extremity.

    Questions/purposes: This case series reports on using the new technology of IM lengthening nails for humeral lengthening. Read More

    miR-23a/b promote tumor growth and suppress apoptosis by targeting PDCD4 in gastric cancer.
    Cell Death Dis 2017 Oct 5;8(10):e3059. Epub 2017 Oct 5.
    State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Jiangsu Engineering Research Center for MicroRNA Biology and Biotechnology, NJU Advanced Institute for Life Sciences (NAILS), School of Life Sciences, Nanjing University, 163 Xianlin Road, Nanjing 210023, Jiangsu, China.
    MicroRNAs (miRNAs) are short non-coding RNAs of 21-23 nucleotides that play important roles in virtually all biological pathways in mammals and in other multicellular organisms. miR-23a and miR-23b (miR-23a/b) are critical oncomiRs (miRNAs that are associated with human cancers) of gastric cancer, but their detailed roles in the initiation and progression of gastric cancer remain to be elucidated. In this study, we found that miR-23a/b were consistently upregulated in gastric cancer tissues. Read More

    Yellow Nail Syndrome With Dramatic Improvement of Nail Manifestations After Endoscopic Sinus Surgery.
    Clin Med Insights Ear Nose Throat 2017 5;10:1179550617718184. Epub 2017 Jul 5.
    Department of Otorhinolaryngology-Head and Neck Surgery, Dokkyo Medical University, Tochigi, Japan.
    Objectives: Yellow nail syndrome (YNS) is a rare disease of unknown cause characterized by the triad of yellow nails, respiratory manifestations, and lymphedema. Although several therapies for YNS have been reported, there is no common consensus in the treatment. In this case report, we present a case of 56-year-old woman with YNS, whose nail manifestation was dramatically improved after endoscopic sinus surgery for the treatment of chronic rhinosinusitis. Read More

    Influence of proximal femur fractures in the autonomy and mortality of elderly patients submitted to osteosynthesis with cephalomedullary nail.
    Rev Bras Ortop 2017 26;52(Suppl 1):57-62. Epub 2017 Aug 26.
    Centro Ortopédico Traumatológico Tijuca, Hospital Tijutrauma, Rio de Janeiro, RJ, Brazil.
    Objective: To determine the autonomy and mortality of elderly patients submitted to proximal femoral osteosynthesis with cephalomedullary nail after hip fracture.

    Methods: Retrospective study with 61 patients with proximal femoral fractures submitted to cephalomedullary nail osteosynthesis. The authors analyzed the medical records and collected information from the preoperative period. Read More

    Pterygium inversum unguis secondary to gel polish.
    J Eur Acad Dermatol Venereol 2017 Sep 28. Epub 2017 Sep 28.
    Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
    Background: Pterygium inversum unguis (PIU) is characterized by the abnormal adherence of the hyponychium to the ventral surface of the nail plate. It can be both unsightly and painful, resulting in morbidity for patients. Gel polish is a popular nail cosmetic that has been reported to cause several complications. Read More

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