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J Photochem Photobiol B 2020 Jun 24;209:111943. Epub 2020 Jun 24.

Amrita Centre for Industrial Research &Innovation, Amrita School of Engineering, Coimbatore 641112, Amrita Vishwa Vidyapeetham, India; Departmentof Chemical Engineering & Materials Science, Amrita School of Engineering, Coimbatore 641112, Amrita Vishwa Vidyapeetham, India. Electronic address:

In modern society, the use of cosmetics has increased extensively; unfortunately, so-called several toxic metal salts are present as the colorant or filler in cosmetics. The ferrous ion (Fe) is one of the metal ions used in cosmetics as a colorant. Ferrous ion (Fe) is a vital component in live cells. Read More

Comb Chem High Throughput Screen 2020 Jun 30. Epub 2020 Jun 30.

Sivas Cumhuriyet University, Faculty of Pharmacy, Department of Pharmaceutical Toxicology . Turkey.

Aim And Scope: Due to the serious toxicological risks and their widespread use, quantitative determination of phthalates in cosmetic products have importance for public health. The aim of this study was to develop a validated simple, rapid and reliable high-performance liquid chromatography (HPLC) method for the determination of phthalates which are; dimethyl phthalate (DMP), diethyl phthalate (DEP), benzyl butyl phthalate (BBP), di-n-butyl phthalate (DBP), di(2- ethylhexyl) phthalate (DEHP), in cosmetic products and to investigate to these phthalate (PHT) levels in 48 cosmetic products marketing in Sivas, Turkey.

Materials And Methods: Separation was achieved by a reverse-phase ACE-5 C18 column (4. Read More

Rev Paul Pediatr 2020 8;38:e2018319. Epub 2020 May 8.

Universidade Federal do Paraná, Curitiba, PR, Brazil.

Objective: To evaluate the hygiene practices and frequency of use of personal hygiene products, cosmetics, and sunscreen among children and adolescents.

Methods: Cross-sectional study with interviews about skincare conducted with caregivers through closed-ended questions. We included patients up to 14 years of age waiting for consultation in pediatric outpatient clinics of a tertiary hospital. Read More

Int J Womens Dermatol 2020 Mar 5;6(2):73-79. Epub 2020 Feb 5.

Department of Dermatology, University of Wisconsin-Madison, Madison, WI, United States.

Healthy nails are functionally and cosmetically important to the daily work of women. The globally increasing market for nail cosmetics reflects the importance of the appearance of nails. This article details the composition of a healthy nail, diagnosis and treatment of nail disorders, use of nail cosmetics and their risks, the impact of the aging process on nails, and the relative risks to nail salon workers. Read More

J Community Health 2020 Mar 26. Epub 2020 Mar 26.

Toxicology Laboratory and Poison Control Center, Faculty of Pharmacy, Campus of Medical Sciences, Saint Joseph University, Damascus Road, Riad El Solh, P.O. Box: 11-5076, Beirut, 1107 2180, Lebanon.

Middle Eastern women seek frequently for self-adornment. Harmful effects of chemicals used in nail care services have involved women worldwide. This study was performed to determine Lebanese women's knowledge and attitudes toward adverse effects of compounds used in nail cosmetics. Read More

Clin Dermatol 2019 Sep - Oct;37(5):561-579. Epub 2019 Jul 17.

Department of Dermatology, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania, USA.

White diseases are a heterogenous group characterized by hypopigmentation or depigmentation. Skin and eye color are determined by the number and size of melanosomes present. Melanin is produced by melanosomes in the melanocytes present within the epidermis of the skin, uvea, and retinal pigmented epithelium (RPE). Read More

Skin Res Technol 2020 May 5;26(3):422-430. Epub 2019 Dec 5.

Department of Drug Sciences, University of Pavia, Pavia, Italy.

Background: Nowadays, nail care products are extremely important both in medical and cosmetic fields. Actually, there are only a very few "in vivo" methods to evaluate the safety and the efficacy of nail products.

Methods: The new apparatus, based on a recently patented technology, is developed for the "in vivo" evaluation of nails in terms of thickness, structural firmness, flattening, and bending properties. Read More

Skin Pharmacol Physiol 2020 20;33(1):44-60. Epub 2019 Nov 20.

Department of Dermatology and Allergology, Charité - Universitätsmedizin Berlin, Berlin, Germany,

Biomechanics of the skin is an important subject in skin research. It has been studied for many decades involving various technologies and methods to characterize and quantify mechanical properties of the skin under different in vivo conditions. The present EEMCO paper reviews the current rel-evant information, providing practical orientation to researchers dedicated to in vivo assessment of biomechanics of skin and its annexes. Read More

Environ Res 2019 12 23;179(Pt A):108756. Epub 2019 Sep 23.

Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, MI, USA. Electronic address:

Background: Organophosphate esters (OPEs) are widely detected among U.S. pregnant women. Read More

Clin Exp Dermatol 2020 Apr 30;45(3):277-283. Epub 2019 Sep 30.

Department of Dermatology, Park Nicollet Health Services, Minneapolis, MN, USA.

Acrylates are synthetic thermoplastic resins used in a multitude of products, ranging from bone cement to artificial nails. They represent an important and increasing cause of both occupational and nonoccupational allergic contact dermatitis. Isobornyl acrylate, an acrylic monomer found within ultraviolet-cured inks, adhesives and various medical devices for diabetes, has emerged as an important sensitizer. Read More

J Dermatol 2019 Nov 4;46(11):1039-1041. Epub 2019 Sep 4.

Department of Dermatology, Iwate Medical University School of Medicine, Morioka, Japan.

We report a case of a manicurist who developed an allergic skin reaction to acrylates, manifested by itchy erythema, papules, vesicles and fissures on her hands, fingertips, forearm and eyelids. Patch tests showed positive reactions to three nail products used: ethylene glycol dimethacrylate, 2-hydroxyethyl methacrylate, ethyl acrylate and 2-hydroxyethyl acrylate in (meth)acrylate series. By using gel nail products, our patient became sensitized to 2-hydroxyethyl methacrylate. Read More

Phytother Res 2019 Dec 3;33(12):3054-3063. Epub 2019 Sep 3.

Department of Pharmacy, University of Naples Federico II, Naples, 80131, Italy.

The nutricosmetics are products and ingredients that act as nutritional supplements to care skin, nails, and hair natural beauty. They work from the inside to promote beauty from within. Nutricosmetic is the latest trend in the beauty industry. Read More

Sci Rep 2019 08 22;9(1):12237. Epub 2019 Aug 22.

Department of Bioscience and Biotechnology, Sejong University, Seoul, 05006, Republic of Korea.

As di(2-ethylhexyl) phthalate (DEHP), one of phthalates, is classified as probable human carcinogens in EPA, acetyltriethyl citrate(ATEC), one of aliphatic esters, could be applied to DEHP substitute. ATEC is used as plasticizers in cosmetics and nail products. Here, we studied whether ATEC might have genotoxic potential and induce glucose tolerance as compared to DEHP. Read More

Dermatitis 2019 Jul/Aug;30(4):259-263

Department of Dermatology, University of Minnesota.

Background: Nail polish is known to contain potentially hazardous chemicals that have been linked to adverse health effects after overexposure. Formaldehyde is used as an antimicrobial, preservative, and nail hardener in select nail products, yet it is a recognized carcinogen and potent allergen in allergic contact dermatitis.

Objective: The aim of this study was to investigate whether formaldehyde is present in nail polishes marketed as formaldehyde-free. Read More

Mar Drugs 2019 Jun 21;17(6). Epub 2019 Jun 21.

School of Pharmacy, University of Camerino, 62032 Camerino, Italy.

Huge amounts of chitin and chitosans can be found in the biosphere as important constituents of the exoskeleton of many organisms and as waste by worldwide seafood companies. Presently, politicians, environmentalists, and industrialists encourage the use of these marine polysaccharides as a renewable source developed by alternative eco-friendly processes, especially in the production of regular cosmetics. The aim of this review is to outline the physicochemical and biological properties and the different bioextraction methods of chitin and chitosan sources, focusing on enzymatic deproteinization, bacteria fermentation, and enzymatic deacetylation methods. Read More

Eye Contact Lens 2020 May;46(3):166-173

Centre for Ocular Lens Research & Education (CORE) (D.L., K.v.D., C.M., S.S., L.J.), School of Optometry & Vision Science, University of Waterloo, Waterloo, ON, Canada; and Currently Alcon Laboratories, Inc (S.S).

Purpose: Contact lens wearers may inadvertently expose their lenses during the lens insertion and removal process or while wearing their lenses to cosmetic products being used. This study investigated the impact of various cosmetics on the physical dimension and optical properties of three recently marketed monthly replacement silicone hydrogel contact lenses.

Methods: In this in vitro study, three monthly replacement silicone hydrogel lens types including senofilcon C (ACUVUE VITA, Johnson & Johnson), samfilcon A (Bausch+Lomb ULTRA, Bausch+Lomb), and lotrafilcon B+EOBO (polyoxyethylene-polyoxybutylene) (AIR OPTIX plus HydraGlyde, ALCON), were individually coated with cosmetic products followed by a 1-hr soak in phosphate-buffered saline. Read More

Clin Pediatr (Phila) 2019 12 16;58(14):1493-1501. Epub 2019 Jun 16.

Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.

A retrospective analysis was conducted by using data from the National Electronic Injury Surveillance System for children <5 years who were treated in US emergency departments (EDs) from 2002-2016) for a cosmetic-related injury. An estimated 64 686 (95% confidence interval = 53 037-76 335) children were treated in EDs for cosmetic-related injuries during the 15-year study period. There was no significant change in the rate (slope = 1. Read More

Indian Dermatol Online J 2019 May-Jun;10(3):288-292

Department of Dermatology and STD, Lady Hardinge Medical College and Associated Hospitals, New Delhi, India.

Introduction: Lichen planus pigmentosus (LPP) is a distinct clinical entity commonly encountered in the Indian population.

Aim: To study the clinicoetiological profile of LPP at a tertiary care hospital.

Methods: A total of 100 patients with clinically and histopathologically confirmed diagnosis of LPP were included. Read More

J Environ Public Health 2019 1;2019:1925863. Epub 2019 Apr 1.

Department of Disease Control and Environmental Health, School of Public Health, College of Health Sciences, Makerere University, P.O. Box 7072, Kampala, Uganda.

Globally, nail salons represent a fast expanding industry and often with low-income cosmeticians. In general, cosmeticians have limited access to safety information about the hazardous materials they handle, which would potentially enable them to minimize workplace exposures. The problem is much pronounced in low- and middle-income countries due to weaknesses in regulation of the industry. Read More

Toxicol Res 2019 Apr 15;35(2):119-129. Epub 2019 Apr 15.

BK21Plus Team, College of Pharmacy, The Catholic University of Korea, Bucheon, Korea.

As the use of cosmetics has greatly increased in a daily life, safety issues with cosmetic ingredients have drawn an attention. Drometrizole [2-(2'-hydroxy-5'-methylphenyl)benzotriazole] is categorized as a sunscreen ingredient and is used in cosmetics and non-cosmetics as a UV light absorber. No significant toxicity has been observed in acute oral, inhalation, or dermal toxicity studies. Read More

Ther Deliv 2019 04;10(4):211-214

Laboratory of Food, Drugs & Cosmetics (LTMAC), University of Brasília (UnB), 70910-900, Brasília, DF, Brazil.

J Cardiothorac Surg 2019 Apr 11;14(1):72. Epub 2019 Apr 11.

Department in cardiac surgery hospital of Damascus university, Damascus, Syria.

Background: Yellow nail syndrome is a rare disease with unknown etiology, Attributed to functional anomalies or disturbance in lymphatic drainage. This condition is characterized by triad of nail discoloration, respiratory or intrathoracic manifestations and lymphedema.

Case Presentation: Twenty days after mitral valve replacement for severe rheumatic mitral valve stenosis, 39 years old woman presented with face tenderness and hearing problems besides stuffy and clogged nose and underwent routin rhinosinusitis therapy. Read More

Chemosphere 2019 Jul 21;226:316-320. Epub 2019 Mar 21.

Graduate Division of Nutritional and Environmental Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan. Electronic address:

Phosphorus-based compounds are used as plasticizers in the manufacture of many products found in the indoor environment. Here we quantitatively investigated dermal exposure to phosphorus-based compounds contained in 45 nail polishes purchased in Japan. The alternative plasticizer triphenyl phosphate (TPhP) was detected in some samples of the nail polishes made in the USA (concentration, 1. Read More

Food Chem Toxicol 2019 May 20;127:163-172. Epub 2019 Mar 20.

Department of Environmental Health Sciences, Graduate School of Public Health, Seoul National University, Seoul, South Korea; Institute of Health and Environment, Seoul National University, Seoul, South Korea. Electronic address:

To estimate realistic exposure to a chemical, the aggregate exposure from multiple consumer products should be considered. A receptor-based aggregate exposure assessment was conducted according to individuals' exposure factors and simultaneous use patterns including co-use and non-use. A product-based aggregate exposure assessment was conducted by product usage rates of population and users' exposure factors. Read More

Singapore Med J 2019 Aug 11;60(8):432-435. Epub 2019 Mar 11.

Department of Anaesthesiology, Singapore General Hospital, Singapore.

Introduction: Pulse oximetry is the standard monitoring technique of functional oxygen saturation (SpO). As the use of fingernail polish has been described to alter SpO readings, its removal is commonly recommended prior to measurement. Gel-based manicures have gained popularity in recent years due to their attractiveness and longevity. Read More

Expert Opin Drug Deliv 2019 04 1;16(4):313-330. Epub 2019 Mar 1.

a Department of Pharmaceutical Technology, Faculty of Pharmacy , University of Coimbra , Coimbra , Portugal.

Introduction: Nanotechnology is an increasingly widespread area of research for its various applications and advantages. Accordingly, nanotechnology has been the focus of investment in different areas of science, namely as a technological strategy for the development of cosmetics formulations. Nanosystems allow for a profit skin penetration and an effective release profile of ingredients, which contributes to superior technological and cosmetic effects. Read More

Clin Exp Dermatol 2019 Aug 21;44(6):599-605. Epub 2019 Feb 21.

Dermatology Department, Brighton and Sussex University Hospitals NHS Trust, Brighton, UK.

Nail cosmetics are used by millions worldwide and the variety of products available is expanding. They are relatively safe, but complications can occur, and patients experiencing complications may present to dermatologists. The physical processes can cause nail thinning and onycholysis, poor technique can promote infection, and consumers may develop allergic contact dermatitis. Read More

J Chromatogr A 2019 May 7;1593:9-16. Epub 2019 Feb 7.

Department of Analytical Chemistry, University of Valencia, 46100, Burjassot, Valencia, Spain. Electronic address:

This work describes a new analytical method useful for monitoring the human exposure to the endocrine-disrupting plasticizer triphenyl phosphate (TPP) via nail polish use. The method allows trace determination of this parent compound and its main metabolite, namely diphenyl phosphate (DPP), in urine samples of nail polish users. The method is based on a novel microextraction technique termed stir bar sorptive-dispersive microextraction (SBSDME) using a magnetic composite made of CoFeO magnetic nanoparticles embedded into a mixed-mode weak anion exchange polymer (Strata-X-AW), followed by liquid chromatography-tandem mass spectrometry (LC-MS/MS). Read More

Environ Int 2019 04 8;125:342-349. Epub 2019 Feb 8.

Wadsworth Center, New York State Department of Health, Department of Environmental Health Sciences, School of Public Health, State University of New York at Albany, Empire State Plaza, P.O. Box 509, Albany, NY 12201-0509, United States; Biochemistry Department, Faculty of Science and Experimental Biochemistry Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia. Electronic address:

The occurrence and profiles of 15 organophosphate flame retardants/plasticizers (OPFRs) (3 chlorinated [Cl-], 2 aryl-, 5 non-Cl alkyl-, and 5 other types of OPFRs) were investigated in indoor air and dust collected from various microenvironments, including homes in the Albany area of New York State, United States. Concurrent indoor air and dust were collected from floors and window sills at homes and fire stations to investigate the partitioning of OPFRs between the vapor and particulate phases of air and dust. The total concentrations of OPFRs in bulk air (vapor plus particulate phases) were found at several tens to hundreds of ng/m, with mean concentrations that ranged from 0. Read More

J Expo Sci Environ Epidemiol 2020 Jan 6;30(1):107-116. Epub 2019 Feb 6.

Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, MI, USA.

Background: Phosphorous-containing flame-retardants (PFRs) are widely detected. They are used both as a flame retardant as well as plasticizer.

Methods: A subset of 230 women and 229 men were recruited from Massachusetts General Hospital fertility clinic between 2005 and 2015. Read More

Contact Dermatitis 2019 Jul 22;81(1):58-60. Epub 2019 Feb 22.

Department of Occupational and Environmental Dermatology, Skåne University Hospital, Lund University, Malmö, Sweden.

J Cosmet Dermatol 2019 Jan 9. Epub 2019 Jan 9.

Faculty of Pharmacy, Department of Cosmetology and Aesthetic Dermatology, Medical University of Lodz, Lodz, Poland.

Background: Hybrid manicure is now a popular method of nail care and nail art, which is associated with its durability. Unfortunately, it has an adverse effect on pH, TOWL and overall nail plates condition and has not been investigated in detail so far.

Aims: The aim of this study was to compare the pH and TOWL of the hand nails after using different primers. Read More

Yakugaku Zasshi 2019 ;139(1):135-140

Tokyo Metropolitan Institute of Public Health.

Nail tips are nail art materials that can be attached to the nail with adhesives. Recently, nail/finger injuries related to nail tips have been reported and one of the causes is considered to be the adhesives used for attaching nail tips. The components of nail adhesives are mostly cyanoacrylate, which is also used as an industrial instant adhesive. Read More

Braz Dent J 2018 Sep-Oct;29(5):475-482

Department of Public Health and Clinic Dentistry, Health Sciences Center, UFPB - Universidade Federal da Paraiba, João Pessoa, PB, Brazil.

This research aimed to determine the influence of fluoridated groundwater and 1,100 ppm fluoride dentifrice on biomarkers of exposure to fluoride in preschoolers. A cross-sectional study was performed on thirty preschoolers recruited from naturally fluoridated and non-fluoridated areas (n=15). Total Daily Fluoride Intake (TDFI) from diet and dentifrice, and Daily Urinary Fluoride Excretion (DUFE) was measured over 24 h. Read More

Am J Infect Control 2018 12 6;46(12):1356-1359. Epub 2018 Jul 6.

College of Graduate Nursing, Western University, Pomona, CA.

Background: Acrylic nails harbor more bacteria than natural nails, and wear is not recommended for health care workers (HCWs). Little is known about the new and popular gel nail products. This study sought to evaluate the bacterial burden of gel nails, standard nail polish, and natural nails on the hands of HCWs. Read More

Environ Res 2019 02 16;169:308-314. Epub 2018 Nov 16.

State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment, Nanjing University, Nanjing 210023, China; Soil and Water Science Department, University of Florida, Gainesville, FL 32611, USA.

Synthetic phenolic antioxidants (SPAs) have been widely used in foods, polymers, and cosmetics, but very limited information is available about their occurrence in human tissues. In this study, five SPAs, namely 2,6-di-tert-butyl-4-methylphenol (BHT), 2-tert-butyl-4-hydroxyanisole (BHA), propyl-, octyl-, and dodecyl-gallate (PG, OG, and DG), and four major metabolites of BHT, including 3,5-di-tert-butyl-4 -hydroxybenzaldehyde (BHT-CHO), 2,6-di-tert-butyl-4-(hydroxymethyl) phenol (BHT-OH), 3,5-di-tertbutyl-4-hydroxybenzoic acid (BHT-COOH), and 2,6-di-tert-butyl-1,4-benzoquinone (BHT-Q), were determined in human fingernail samples collected from Nanjing, China. Total concentrations of the nine target analytes (∑SPAs) were 523-14,000 ng/g. Read More

An Bras Dermatol 2018 Nov/Dec;93(6):930-931

Interdisciplinary Field of Biomedical Sciences, Faculdade de Medicina, Universidade Federal do Rio Grande, Rio Grande (RS), Brazil.

Clin Rev Allergy Immunol 2019 Feb;56(1):119-128

Ohio University, 2359 E Main St., Columbus, OH, 43209, USA.

Allergic contact dermatitis (ACD) to cosmetics is extremely common-probably the most common reason patients present for patch testing. The diagnosis should initially be suspected based on the patient history and the distribution of the dermatitis. Once the diagnosis is suspected, empiric recommendations for low allergenicity products should be implemented until patch testing is performed. Read More

Pan Afr Med J 2018 6;30:103. Epub 2018 Jun 6.

Division of Dermatology, Groote Schuur Hospital, University of Cape Town, Observatory Cape Town, South Africa.

Angioedema is a type-1 hypersensitivity reaction that can be life threatening. It affects the skin airways and the gastrointestinal tract. Henna is a green powder used to dye skin and nails. Read More

Int J Cosmet Sci 2018 Dec 6;40(6):555-564. Epub 2018 Dec 6.

Coatings Research Institute, Eastern Michigan University, Ypsilanti, MI, USA.

Objective: Gel nail polishes represent an advanced class of nail polishes, with the ability to cure under ultraviolet (UV) radiation, and consequently demonstrate improved properties and greater durability compared to conventional nail polishes. Most gel nail polishes available today are based on petrochemical resources, making them unsustainable. Bio-based materials are excellent renewable resources, with high potential for meeting final-product performance, cost, and environmental needs. Read More

Int Arch Occup Environ Health 2019 Jan 1;92(1):141-153. Epub 2018 Oct 1.

School of Public Health, Boston University, Boston, MA, USA.

Purpose: Exposures of nail salon technicians have received attention due to the potentially toxic materials used in nail products, which include volatile organic compounds (VOCs) such as formaldehyde and methyl methacrylate (MMA). This study characterized area and personal concentrations and other indoor air parameters in 17 nail salons in fall and winter seasons in three areas of Michigan.

Methods: VOC samples were analyzed using thermal desorption, gas chromatography and mass spectroscopy, and the VOC composition of 35 nail products (e. Read More

Int J Dermatol 2019 Mar 23;58(3):311-318. Epub 2018 Sep 23.

Department of Cosmetology and Aesthetic Dermatology, Faculty of Pharmacy, Medical University of Lodz, Lodz, Poland.

Background: The purpose of this study was to evaluate the effect of nail polish, gel polish hybrid, gel nail, and acrylic nail powder and the removal of these formulas on the nail plates properties, particularly the influence of different coatings on morphology and pH.

Methods: The morphology and structure of nail plates were analyzed with use of scanning electron microscopy. The pH values of the nail plates of hands were measured using the system Courage & Khazaka. Read More

J Cardiothorac Surg 2018 Sep 11;13(1):93. Epub 2018 Sep 11.

Department of Cardiothoracic Surgery, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA, 94305, USA.

Background: Yellow nail syndrome is a rare condition considered secondary to functional anomalies of lymphatic drainage. Yellow nail syndrome is diagnosed through the triad of intrathoracic findings (30% being pleural effusions), nail discoloration, and lymphedema, with any two features sufficient for diagnosis. We report the second case of post-operative yellow nail syndrome. Read More

PLoS One 2018 16;13(8):e0202608. Epub 2018 Aug 16.

Science and Engineering Faculty, Queensland University of Technology, Brisbane, Queensland, Australia.

Keratin is the structural protein in hair, nails, feathers and horns. Keratin is recalcitrant, highly disulfide bonded and is generally inaccessible to common proteases. Only certain types of proteases, called keratinases, are able to cleave the peptide bonds within the keratin structure. Read More

J Forensic Leg Med 2018 Aug 10;58:205-211. Epub 2018 Jul 10.

National Poisons Information Centre, Department of Pharmacology, All India Institute of Medical Sciences, New Delhi, 110029, India. Electronic address:

Extensive use of different chemicals in various fields and their easy availability has led to an increased incidence of accidental and intentional poisoning in developing countries including India. A diverse range of household products commonly used for domestic purposes comprise pesticides, household cleaners, thermometer mercury, antiseptics, kerosene, paint thinners etc. Any of these products, if misused or mishandled can cause poisoning. Read More

Dermatol Online J 2018 Apr 15;24(4). Epub 2018 Apr 15.

Department of Dermatology, University of California San Diego, La Jolla, California.

5-fluorouracil, a fluoropyrimidine antineoplastic drug, is used to topically treat actinic keratoses. Local skin reactions to the medication are common and anticipated. However, severe adverse events from topical 5-fluorouracil are rare and unexpected. Read More

Contact Dermatitis 2018 Aug 11;79(2):81-84. Epub 2018 Jun 11.

Department of Dermatology, University Hospitals KU Leuven, Leuven, Belgium.

Background: Acrylates and methacrylates are acrylic resin monomers that are known to induce skin sensitization as a result of their presence in different materials, such as nail cosmetics, dental materials, printing inks, and adhesives. Allergic contact dermatitis resulting from the use of modern wound dressings containing them has only rarely been reported.

Objectives: To describe 2 patients who developed allergic contact dermatitis caused by acrylic-based modern medical dressings and/or adhesives. Read More

Contact Dermatitis 2018 Sep 4;79(3):184-185. Epub 2018 May 4.

Skin and Cancer Foundation Inc, Carlton, Victoria, Australia.

J Expo Sci Environ Epidemiol 2018 05;28(3):242-250

Department of Dermatology, Dankook University Medical Center, Chungnam, Korea.

Despite daily exposure to chemicals in cosmetic products, there are few studies on the exposure levels to cosmetics particularly in Asians. We sought to investigate the usage pattern of cosmetics, including eye makeup products, fragrances, color makeups, and hair and nail care products, in Koreans. An online survey of 1,800 participants (908 males and 892 females, aged 15-59 years) from 5 Metropolitan cities (Seoul, Incheon, Daejeon, Daegu, and Busan) in Korea was conducted. Read More

Dermatol Online J 2018 Mar 15;24(3). Epub 2018 Mar 15.

Department of Dermatology and Cutaneous Biology, Thomas Jefferson University, Philadelphia, Pennsylvania.

Gel manicures have become a popular beauty trend in recent years. The specially formulated nail polish must undergo curing under light-based units. The majority of these curing lamps emit high-intensity ultraviolet A, which can cause skin damage and increase the risk for skin cancers. Read More