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Molecules 2018 Dec 7;23(12). Epub 2018 Dec 7.

Department of Legal Medicine, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan.

A simple, sensitive, and rapid extraction method based on high-frequency (H-F) heating was developed for drug analysis in human nails. A human nail was placed in a glass tube with an extraction solvent (methanol and 0.1% formic acid; 7:3, /), and a ferromagnetic alloy (pyrofoil) was wrapped in a spiral around the glass tube. Read More

Biol Psychol 2018 Dec 10. Epub 2018 Dec 10.

General Pediatrics, Neonatology and Pediatric Cardiology, Heinrich-Heine-University, Moorenstraße 5, 40225, Düsseldorf, Germany. Electronic address:

This study assesses the impact of prenatal stress and intrauterine growth restriction (IUGR) on the dehydroepiandrosterone (DHEA) and dehydroepiandrosteronesulfate (DHEAS) concentrations in nails of newborns. Nail samples were gained from 56 newborn infants. The concentration of DHEA and DHEAS was measured by liquid chromatography/tandem mass spectrometry. Read More

Geriatr Orthop Surg Rehabil 2018 11;9:2151459318799856. Epub 2018 Nov 11.

Ain-Shams University, Cairo, Egypt.

Introduction: Distal femoral fractures in elderly population had recorded an increase in incidence in the last 2 decades. Lateral distal femoral locking plating is considered one of the best options especially when dealing with comminuted fractures but varus collapse of the medial femoral condyle occurs frequently in patients with osteoporosis. Anatomical reduction of the fracture with stable rigid fixation using double-plating approach allows early mobilization of geriatric population and prevents varus collapse minimizing the comorbidities in such fractures. Read More

Tech Orthop 2018 Dec 25;33(4):267-270. Epub 2017 Dec 25.

The University of Central Florida College of Medicine, Orlando, FL.

When persistent rotation of the femur remains into adolescence, it can cause functional limitations such as fatigue, anterior knee pain, and frequent tripping. In these cases, derotation of the femur via osteotomy is often performed. We report preliminary results of bilateral derotational osteotomy for excessive femoral anteversion or retroversion using the modified intramedullary nail technique. Read More

Rev Esp Cir Ortop Traumatol 2018 Dec 9. Epub 2018 Dec 9.

Ortopedia y Traumatología, Universidad Nacional de Colombia, Bogotá, Colombia.

Introduction: radial longitudinal deficiency (RLD) includes bone, musculotendinous and neurovascular abnormalities of multifactorial aetiology of the radial side of the upper extremity. Treatment includes improving the length of the limb, the appearance and functioning of the hand. The aim of this study was to present our experience in a series of patients attended over the past 15 years and to describe the clinical and radiological results. Read More

Phlebology 2018 Dec 12:268355518818619. Epub 2018 Dec 12.

1 Department of Dermatovenereology, University Medical Centre Ljubljana, Ljubljana, Slovenia.

Objective: The prevalence of toenail alterations in chronic venous disease has only rarely been studied. We aimed to establish the frequency and clinical characteristics of toenail onychomycosis in chronic venous disease.

Methods: We included 80 adult patients, in all stages of chronic venous disease. Read More

Front Bioeng Biotechnol 2018 21;6:174. Epub 2018 Nov 21.

Department of Engineering, University of Perugia, Perugia, Italy.

The Marchetti-Vicenzi's nail is an intramedullary device where six curved nails are kept straight by a closing ring in order to allow their insertion into the medullary canal of a long bone; in a following step, these nails stabilize the fracture due to the ring withdrawal and to the consequent elastic expansion of the nails. Pre-clinical testing of this sort of device is strongly advocated in order to be able to foresee their stability inside the medullary canal and to quantify their stiffening action on a broken bone. In this numerical work, an MB (Multi Body) model of the device has been developed, with the dual purpose of evaluating forces between the bone and the system components during its progressive opening and verifying the behavior of the stabilized bone when it undergoes external loading. Read More

Nanotechnology 2018 Nov 28. Epub 2018 Nov 28.

Micro-Nano Technology Center, Beijing Institute of Technology, 5 Zhongguacun South Street, Haidian District, Beijing 100081, Beijing, CHINA.

Nanoscale heterostructures, which incorporate two or more materials such as core-shell nanocrystals, core-crown nanoplates, or seeded nanorods, allow better control of the optical, electrical and magnetic properties that are inaccessible in single component nanostructure, yet their variety and controlled growth are still challenging. Here, a nail-like Mn-doped CdS/CdBr2 hetero-nanostructure, which has a hexagonal plate on top of a nanowire, is firstly fabricated by a simple one-step thermal evaporation process. According to the characterization results, its growth mechanism could be obtained, in which the manganese bromide precursor plays a critical role in the formation of such nail morphology. Read More

Biomed Mater 2018 Dec 4. Epub 2018 Dec 4.

Rossijskij nauchnyj tsentr Vosstanovitel'naja travmatologija I ortopedija imeni akademika G A Ilizarova, Kurgan, RUSSIAN FEDERATION.

This study aims to investigate the comparative study of calcium phosphate coatings for flexible intramedullary nails (FINs) used to lengthen long tubular bones. The presence of a calcium phosphate coating deposited by micro-arc oxidation or a composite coating based on a copolymer of vinylidene fluoride with tetrafluoroethylene (VDF-TeFE) and hydroxyapatite (HA) on the surface of the FIN significantly enhanced the regeneration of bone in the area of osteotomy during limb lengthening by combined osteosynthesis. The investigation of the physicochemical properties of the FIN coated with calcium phosphate via micro-arc oxidation demonstrated that the improved bone tissue formation resulted from favorable conditions for adhesion, proliferation, and differentiation of multipotent stem cells into osteoblasts on the coating surface. Read More

Eur J Orthop Surg Traumatol 2018 Dec 6. Epub 2018 Dec 6.

Siena College, Loudonville, NY, 12211, USA.

Introduction: The aim of this study was to evaluate the effect on union results of the application of cerclage cable around the lateral femoral wall (LFW) in postoperative fracture displacement.

Patients And Methods: A retrospective evaluation was made of all the cases of reverse intertrochanteric fractures over a 7-year period in a trauma center. The study included 69 fractures treated with intramedullary nailing. Read More

Reumatol Clin 2018 Dec 3. Epub 2018 Dec 3.

Departamento de Reumatología, Hospital Universitario San Cecilio, Granada, España.

Aims: To describe the methodology of REAPSER (Spanish Registry of Recent-onset Psoriatic Arthritis), its strengths and limitations. The aim of this study is to identify prognostic factors for the clinical and radiographic course in a cohort of patients with psoriatic arthritis (PsA) diagnosed within 2years of symptom evolution.

Methods: Multicenter, observational and prospective study (with 2-year follow-up including annual visits). Read More

J Glaucoma 2018 Dec 11. Epub 2018 Dec 11.

Glaucoma and anterior segment, Dr. Shroff's charity eye hospital, Delhi.

Ectodermal dysplasia is a disorder that occurs due to abnormalities of ectodermal structures such as skin, teeth, hair, nails, and eccrine glands. Approximately 200 different conditions have been identified as ectodermal dysplasia, the most common being hypohidrotic ectodermal dysplasia (HED). It is characterized by hypotrichosis (sparse scalp or body hair), hypodontia (absent or malformed teeth) and hypohidrosis (reduced ability to sweat). Read More

J Orthop Trauma 2019 Jan;33 Suppl 1:S27-S32

*Institute for Biomechanics, BG Unfallklinik Murnau, Murnau, Germany; and †Institute for Biomechanics, Paracelsus Medical University Salzburg, Salzburg, Austria.

Fractures of the femoral neck can occur in young healthy individuals due to high loads occurring during motor vehicle accidents, impacts, or falls. Failure forces are lower if impacts occur sideways onto the greater trochanter as compared with vertical loading of the hip. Bone density, bone geometry, and thickness of cortical bone at the femoral neck contribute to its mechanical strength. Read More

J Pediatr Orthop 2019 Jan;39(1):e12-e17

Children's Healthcare of Atlanta.

Introduction: The insertion of 2 elastic stable intramedullary nails (ESINs) is a common treatment for pediatric femur fractures. However, the use of this technique in length-unstable or metadiaphyseal fractures has historically been associated with higher complication rates. To improve stability, the addition of a third ESIN has been assessed biomechanically and clinically, but the addition of a fourth nail has only been evaluated biomechanically. Read More

Curr Health Sci J 2015 Jul-Sep;41(3):233-238. Epub 2015 Mar 15.

Rheumatology Department, University of Medicine and Pharmacy of Craiova, Faculty of Medicine, Romania.

Background: Early inflammatory arthritis (EIA) a condition defined by joint swelling, with or without morning stiffness, and/or swelling of metacarpophalangeal and/or metatarsophalangeal joints. Nail fold video-capillaroscopy (NVC) is important for the evaluation of microcirculation in vivo. There are limited data about the role of NVC in EIA. Read More

Contact Dermatitis 2018 Dec 7. Epub 2018 Dec 7.

Department of Dermatology, Hospital General Universitario de Alicante. Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL-FISABIO Foundation), Alicante, Spain.

Undecylenic acid (CAS no. 112-38-9) has antifungal and antibacterial effects. For this reason, it is used along with imidazole antifungals. Read More

Forensic Sci Med Pathol 2018 Dec 10. Epub 2018 Dec 10.

Unit of Legal Medicine, Department of Physiology and Pharmacology, University of Cantabria, Av Cardenal Herrera Oria s/n, 39011, Santander, Spain.

Humans constantly lose epithelial cells, and these biological traces are frequently studied in the context of criminal investigations. The objective of this work was to examine the genetic profile in samples of forensic interest (nail and skin epithelial cells) of bone marrow transplant patients and discuss its forensic and clinical implications. The genetic profile of nail, epidermal cells and blood samples of patients receiving HSCT was analyzed by the amplification and sequencing of 38 insertion/deletion polymorphisms and 15 short tandem repeat polymorphisms. Read More

Rheumatol Int 2018 Dec 10. Epub 2018 Dec 10.

Department of Social Psychology and Methodology, Facultad de Psicología, Universidad Autónoma de Madrid, Madrid, Spain.

To assess the discriminative utility of nail features detected by B-mode (BM) and color Doppler (CD) ultrasound (US) between patients with psoriasis (PsO) and psoriatic arthritis (PsA) and healthy controls. Sixty patients with PsA, 21 patients with PsO, and 20 healthy controls were prospectively included. All patients underwent a dermatologic assessment and PsA patients also a rheumatologic assessment. Read More

Rev Chilena Infectol 2018 ;35(3):262-265

Laboratorio de Micología, Universidad de Valparaíso, Valparaíso, Chile.

Background: Dermatophytoses are frequent infections in human, which are produced by fungus genera Trichophyton, Microsporum and Epidermophyton.

Aim: To determine frequency of E. floccosum in isolated dermatophyte in a laboratory from Valparaíso during the last three decades, in addition to knowing the most frequent localization, age and gender of patients affected by this agent. Read More

J Cutan Aesthet Surg 2018 Jul-Sep;11(3):161-163

Dermcos Skin Care Clinic, Gurugram, Haryana, India.

J Cutan Aesthet Surg 2018 Jul-Sep;11(3):143-147

Department of Dermatology, Topiwala National Medical College and B. Y. L. Nair Charitable Hospital, Mumbai, Maharashtra, India.

The clinical diagnosis of benign and malignant nail tumors can be difficult. Dermoscopy can provide a clue to the diagnosis but nail biopsy is the gold standard in establishing the diagnosis. Here, we report three cases of rare nail tumors, that is, onychopapilloma, onychomatricoma, and subungual osteochondroma, which were diagnosed on histopathology and managed surgically. Read More

J Cutan Aesthet Surg 2018 Jul-Sep;11(3):140-142

Department of Dermatology and STD, University College of Medical Sciences and Guru Teg Bahadur Hospital, Dilshad Garden, Delhi, India.

Onychoheterotopia (ectopic nail) is a rare condition characterized by the development of nail tissue, distinct from the normal nail unit. It is usually acquired following traumatic inoculation of nail matrix; the congenital variety being less common. The exact pathogenesis of the disease is not clear. Read More

Bioact Mater 2019 Mar 23;4(1):17-21. Epub 2018 Nov 23.

Ministry-of-Education Key Laboratory for the Green Preparation and Application of Functional Materials, Hubei Key Laboratory of Polymer Materials, School of Materials Science & Engineering, Hubei University, Wuhan, 430062, China.

Bone-implant materials are important for bone repairing and orthopedics surgery, which include bone plates and bone nails. These materials need to be designed not only considering its biostability and biocompatibility, but also their by-products induced infection after therapy or long-time treatment . Thus, the development of novel implant materials is quite urgent. Read More

Indian J Orthop 2018 Nov-Dec;52(6):611-615

Orthopaedic Surgery Department, Section of Hand Surgery, Changhua Christian Hospital, Changhua, Taiwan, ROC.

Background: A variety of surgical techniques for treating mallet fracture finger has been reported with different outcomes and complications. However, the optimal procedure remains controversial. This study describes surgical outcomes of mallet fractures of the finger with distal phalanx treated by modified pull-out wire fixation with Kirschner wire (K-wire) stabilization of the DIP joint in hyperextension. Read More

Best Pract Res Clin Rheumatol 2018 04 5;32(2):295-311. Epub 2018 Oct 5.

Division of Rheumatology, University of Ottawa, 1967 Riverside Drive, Ottawa, ON, K1H 7W9, Canada; The Ottawa Hospital Research Institute, University of Ottawa, 1967 Riverside Drive, Ottawa, ON, K1H 7W9, Canada. Electronic address:

Psoriatic arthritis (PsA) is a chronic inflammatory disease that affects different structures of the musculoskeletal system in addition to the skin and the nail. The complexity of the disease had been a barrier to understand the pathogenesis and define valid outcome tools; however, our understanding about the disease has considerably increased with time mainly because of the advances in imaging, new discoveries in genetics and underlying inflammatory pathways, and better understanding of the epidemiology of the disease and environmental risk factors. The purpose of this review is to summarize developments and changes in epidemiology, risk factors for developing PsA, and outcome measures with a focus on data obtained in the last 10 years. Read More

Lung Cancer 2018 Dec 13;126:41-47. Epub 2018 Oct 13.

Department of Respiratory Medicine, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan.

Objective: The efficacy and safety of afatinib in elderly patients with EGFR-mutated non-small-cell lung cancer (NSCLC) have not been evaluated. This study aimed to assess the efficacy and safety of afatinib in elderly chemotherapy-naive patients with NSCLC harboring sensitive EGFR mutations.

Materials And Methods: We prospectively assessed the clinical effects of afatinib as a first-line treatment for elderly (age ≥70 years) NSCLC patients with EGFR mutations (exon 19 deletion or exon 21 L858R mutation). Read More

Injury 2018 Dec 3;49 Suppl 4:S58-S62. Epub 2018 Dec 3.

School of Medicine, University of Bari "Aldo Moro"- AOU Consorziale "Policlinico", Department of Basic Medical Sciences, Neuroscience and Sense Organs, Orthopaedic and Unit, Bari, Italy.

The treatment of open distal tibia fractures remains challenging, particularly when the fracture involves severe soft tissue damage and segmental bone loss. We present the case of a 33-year-old woman who sustained an open distal tibia fracture type 43-A3.3, with segmental bone loss, and a closed bifocal fibular fracture. Read More

Injury 2018 Dec 3;49 Suppl 4:S43-S47. Epub 2018 Dec 3.

Department of Orthopaedics and Traumatology, Di Venere Hospital, Bari, Italy.

Nonunion of the humeral shaft occurs in 2%-10% of nonsurgically treated fractures and in up to 15% of fractures treated by primary open reduction and internal fixation. Gunshot humerus shaft fractures are a frequent type of injury; the degree of comminution and bone loss, as well as soft tissue disruption may influence the healing process, causing major sequelae with loss of function. Here we describe a 30 years old midshaft nonunion of the humerus, that occurred in a young woman after a gunshot. Read More

Injury 2018 Dec;49(12):2121-2131

AEPSM, Montevideo, Uruguay.

Introduction: Femoral neck fractures (FNF) after internal fixation of trochanteric fractures (AIFTF) with the implant in situ (WIIS) are uncommon. Publications of FNFAIFTFWIIS are rare. The purpose of this systematic review of the literature is to report on the frequency, risk factors, mechanisms, clinical presentation, diagnostic and therapeutic modalities, outcomes and the eventual prevention of this complication. Read More

J Int Med Res 2018 Dec 11:300060518816185. Epub 2018 Dec 11.

1 Department of Orthopaedic Surgery, the Third Hospital of Hebei Medical University, Shijiazhuang, PR China.

Objective: Unstable femoral neck fractures are typically high-angled shear fractures caused by high-energy trauma. Internal fixation of femoral neck fractures with placement of parallel cannulated screws in an inverted triangle configuration is commonly performed in the clinical setting. This study was performed to investigate the primary results of intramedullary nailing with cannulated screws for the treatment of unstable femoral neck fractures in young and middle-aged patients. Read More

Acta Ortop Mex 2018 May-Jun;32(3):163-166

Servicio de Cirugía Ortopédica y Traumatología, Hospital de Sabadell. Institut Universitari Parc Taulí Universitat Autònoma de Barcelona, España.

We present the case of an 81-year-old woman who was followed up by the Rheumatology Service for osteoporosis and treated with bisphosphonates for more than five years. She reported a fracture of the distal third of the contralateral femur by a low energy mechanism, treated with retrograde intramedullary nailing the previous year. She presented a clinic of cruralgia and left gonalgia, without previous trauma. Read More

Acta Ortop Mex 2018 May-Jun;32(3):126-130

Centro de Evaluación de Tecnologías, Universidad CES, Medellín, Colombia.

Introduction: Cephalomedullary nails are used for the treatment of hip fractures; however, there are few studies that allow identifying data on the complications of the use of these devices and the results in terms of restoration of the functionality of the patient.

Methods: A cross-sectional study of patients with femur fracture was conducted during the period from January 2008 to December 2012. Data on demographic and clinical variables were collected. Read More

Acta Derm Venereol 2018 Dec 6. Epub 2018 Dec 6.

Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Via Massarenti 1, IT-40138 Bologna, Italy.

Nail psoriasis affects 50-79% of patients with skin psoriasis and up to 80% of patients with psoriatic arthritis, and can also represent a negative prognostic factor in individuals with plaque psoriasis. Treatments for nail psoriasis are limited, as nails are often difficult to treat with topical therapies alone, and relapse is common. Among different systemic agents, secukinumab, a fully human monoclonal antibody targeting interleukin (IL)-17A, is the only antibody supported by a trial specifically conducted in patients with nail psoriasis (the TRANSFIGURE trial) and has the longest follow-up available to date. Read More

Hemodial Int 2018 Dec 6. Epub 2018 Dec 6.

Department of Nephrology, Cleveland Clinic Akron General, Akron, Ohio, USA.

Skin manifestations are commonly seen in end stage renal disease (ESRD). Skin involvement in this population can be extensive and dramatically worsen quality of life. Close observation of the skin and nails of ESRD patients by clinicians allows for timely diagnosis and treatment, which ultimately improves quality of life and reduces mortality. Read More

Injury 2018 Dec 3;49 Suppl 4:S48-S57. Epub 2018 Dec 3.

Hip Department - Orthopedic and Trauma v, I.R.C.C.S. Policlinico San Donato, 20097, San Donato Mil.se, Milan, Italy; Division of Orthopaedic Surgery, McMaster University, Canada.

An infected non-union is a major and potentially devastating complication following bone fractures. It is often debilitating for the patients, physically and psychologically, because of its long healing period and emotional toll on patient and caregivers. Different surgical procedures (in one or two stages) are described in literature for its treatment. Read More

Injury 2018 Dec 3;49 Suppl 4:S39-S42. Epub 2018 Dec 3.

Orthopaedic and Traumatology Division, Department of Medicine and Science of Aging, University of Study "G. d'Annunzio" Chieti-Pescara, Italy.

A fit 26 year-old-man presented to our Department with an open fracture of the left tibial shaft (AO 42-C3). The fracture was initially treated with an External Fixator, which was replaced by an intramedullary Grosse Kempf nail after 4 months. In the following year he developed an atrophic non-union and we witnessed the increasing bone resorption at the fracture site which led to the nail breakage. Read More

Injury 2018 Dec 3;49 Suppl 4:S29-S33. Epub 2018 Dec 3.

Orthopaedics and Trauma Unit, Emergency Department, Ospedale Policlinico San Martino, Largo R. Benzi 10-16132, Genoa, Italy.

Septic nonunion is one of the most serious complications after an open fracture because both the infection and the bone defect need to be dealt with. Treatment is always protracted and expensive, and the result is uncertain. In the 1980s, Masquelet first described the technique of the induced membrane and autologous bone grafting to manage critical size bone defects. Read More

Injury 2018 Dec 3;49 Suppl 4:S21-S24. Epub 2018 Dec 3.

Department of Traumatology, IRCCS Humanitas Research Hospital, Milano, Italy.

The large bone defect treatment is a challenge issue in modern orthopaedic trauma surgery. One of the most used technique is the Masquelet's technique. In this case report we used a modified Masquelet technique to fill a six centimeters bone gap in the proximal femur. Read More

Future Microbiol 2018 Dec 3. Epub 2018 Dec 3.

Departamento de Análises Clínicas e Biomedicina, Universidade Estadual de Maringá (UEM), Avenida Colombo, 5790, Maringá, PR, CEP 87020-900, Brazil.

Aim: To evaluate and characterize the etiopathogenesis of the fusarial onychomycosis in an ex vivo study through fragments of sterile human nail, without the addition of any nutritional source.

Materials & Methods: The infection and invasion of Fusarium oxysporum in the nail were evaluated by scanning electron microscopy (SEM), CFU, matrix, histopathology and Fourier Transform Infrared Spectrometer coupled to an equipment with diamond accessory (FTIR-ATR).

Results: F. Read More

J Dermatol 2018 Dec 3. Epub 2018 Dec 3.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Indian Dermatol Online J 2018 Nov-Dec;9(6):481-483

Consultant Dermatologist, "Pranab", Ismile, Asansol, West Bengal, India.

In the early and mid-nineteenth century Europe, ringworm of the scalp was a vexing problem. It affected children in such numbers that the famous Hôpital Saint-Louis of Paris had a separate Tinea School. Before advent of radiation method of epilation, painful method of peeling was the mainstay of management. Read More

Indian Dermatol Online J 2018 Nov-Dec;9(6):448-451

Department of Dermatology, Seth G.S. Medical College and King Edward Memorial Hospital, Mumbai, Maharashtra, India.

Schopf-Schulz-Passarge syndrome (SSPS) is a rare type of ectodermal dysplasia that has autosomal recessive inheritance. It is characterized by palmoplantar keratoderma, hypodontia, hypotrichosis, nail dystrophy, and multiple periocular and eyelid apocrine hidrocystomas. A 36-year-old male presented with multiple eyelid and periocular apocrine hidrocystomas, ichthyosis, palmoplantar keratoderma, hypodontia, nail dystrophy, and thin scalp hair. Read More

Indian Dermatol Online J 2018 Nov-Dec;9(6):373-382

Department of Dermatology and STD, VMMC and Safdarjung Hospital, New Delhi, India.

Nail unit is a complex skin appendage offering natural barrier to drug penetration by virtue of its unique anatomy. This is the reason why topical as well as oral therapies can be largely ineffective when dealing with nail diseases. Intralesional (injectable therapies) offer a practical solution in this scenario. Read More

Indian J Dermatol 2018 Nov-Dec;63(6):515-517

Department of Clinical Analysis and Biomedicine, State University of Maringá, Paraná, Brazil.

Onychomycosis is a fungal nail infection, considered as a public health problem because it is contagious and it interferes with the quality of life. It has long and difficult treatment, with many side effects and high cost. Propolis extract (PE) is a potential alternative to conventional antifungal agents because it has low cost, accessibility, and low toxicity. Read More

Indian J Dermatol 2018 Nov-Dec;63(6):490-495

Department of Dermatology, Government Medical College, Kottayam, Kerala, India.

Background: The incidence of dermatophytosis is increasing over the last few years and there are many cases which are recurrent and chronic.

Aim: The aim was to study the host and pathogen factors in dermatophytosis, to identify the species responsible, and to study the histopathological features of chronic dermatophytosis.

Materials And Methods: It was a descriptive study conducted in the Department of Dermatology for a period of 1 year and all patients who were clinically diagnosed as dermatophytosis were included. Read More

Knee 2018 Nov 29. Epub 2018 Nov 29.

Houston Methodist Othopedics & Sports Medicine, Houston, TX, United States of America. Electronic address:

Nail-patella syndrome (NPS) or hereditary onycho-osteodyaplasia is a rare genetic condition involving a mutation in the LMX1B gene affecting nails, elbows, knees, and pelvis. Due to the regulatory functions of the gene in many developmental processes through the body, patients with NPS experience wide-ranging musculoskeletal problems including patellar instability, fingernail anomalies, iliac exostoses/horns, and elbow abnormalities. The patellar changes often involve aplasia, hypoplasia, and chronic dislocation. Read More

Injury 2018 Nov 24. Epub 2018 Nov 24.

Servicio de Traumatologia y Cirugia Ortopedica, Complexo Hospitalario Universitario de Santiago de Compostela, Spain; Musculoskeletal Pathology Group, Institute IDIS, Lab 18, Spain.

Purpose: Antegrade intramedullary nailing is an alternative for humeral shaft fracture treatment. This surgical technique can be especially demanding in some fracture patterns, leading to problems like malunion and non-union. The purpose of our study is to demonstrate that the use of a nail with cerclage wires could be a safe procedure that facilitate reduction, specially in fractures with abduction of the proximal fragment. Read More

Braz Dent J 2018 Sep-Oct;29(5):475-482

Department of Public Health and Clinic Dentistry, Health Sciences Center, UFPB - Universidade Federal da Paraiba, João Pessoa, PB, Brazil.

This research aimed to determine the influence of fluoridated groundwater and 1,100 ppm fluoride dentifrice on biomarkers of exposure to fluoride in preschoolers. A cross-sectional study was performed on thirty preschoolers recruited from naturally fluoridated and non-fluoridated areas (n=15). Total Daily Fluoride Intake (TDFI) from diet and dentifrice, and Daily Urinary Fluoride Excretion (DUFE) was measured over 24 h. Read More