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    476 results match your criteria Nail Cosmetics

    1 OF 10

    The cosmetic and dermatological potential of keratin hydrolysate.
    J Cosmet Dermatol 2017 Feb 6. Epub 2017 Feb 6.
    Department of Polymer Engineering, Faculty of Technology, Tomas Bata University in Zlin, Zlin, the Czech Republic.
    Background: Although keratin hydrolysates have become established as standard components in hair and nail cosmetics, studies on the moisturizing effects of keratin hydrolysates do not appear among contemporary literature.

    Objectives: To test if adding keratin hydrolysate into an ointment base increases hydration of the skin and improves skin barrier function, or diminishes trans-epidermal water loss.

    Methods: Formulations were prepared containing 2%, 4%, and 6% keratin hydrolysates (based on weight of the ointment base). Read More

    UV-curable gels as topical nail medicines:In vivo residence, anti-fungal efficacy and influence of gel components on their properties.
    Int J Pharm 2016 Nov;514(1):244-254
    UCL School of Pharmacy, 29-39 Brunswick Square, London, WC1N 1AX, UK. Electronic address:
    UV-curable gels, used as nail cosmetics for their in vivo durability, were reported to be promising as topical nail medicines. Our first aim was thus to investigate whether such durability applies to drug-loaded formulations. This was found to be true. Read More

    Chemical and physical strategies in onychomycosis topical treatment: A review.
    Med Mycol 2016 Oct 4. Epub 2016 Oct 4.
    Laboratory of Food, Drugs and Cosmetics (LTMAC). School of Health Sciences, University of Brasília. Campus Universitário Darcy Ribeiro, s/n, 70910-900, Brasília, DF, Brazil
    Onychomycosis is a fungal infection of the fingernails or toenails caused by dermatophytes, nondermatophytes, moulds, and yeasts. This condition affects around 10-30% people worldwide, negatively influencing patients' quality of life, with severe outcomes in some cases. Since the nail unit acts as a barrier to exogenous substances, its physiological features hampers drug penetration, turning the onychomycosis treatment a challenge. Read More

    External lead contamination of women's nails by surma in Pakistan: Is the biomarker reliable?
    Environ Pollut 2016 Nov 21;218:723-727. Epub 2016 Aug 21.
    Department of Environmental and Preventive Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan. Electronic address:
    Adverse health effects of heavy metals are a public health concern, especially lead may cause negative health impacts to human fetal and infantile development. The lead concentrations in Pakistani pregnant women's nails, used as a biomarker, were measured to estimate the lead exposure. Thirteen nail samples out of 84 nails analyzed contained lead higher than the concentration (13. Read More

    Optical isopropanol biosensor using NADH-dependent secondary alcohol dehydrogenase (S-ADH).
    Talanta 2016 Oct 19;159:418-24. Epub 2016 Jun 19.
    Graduate school of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8549, Japan; Department of Biomedical Devices and Instrumentation, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, Japan. Electronic address:
    Isopropanol (IPA) is an important solvent used in industrial activity often found in hospitals as antiseptic alcohol rub. Also, IPA may have the potential to be a biomarker of diabetic ketoacidosis. In this study, an optical biosensor using NADH-dependent secondary alcohol dehydrogenase (S-ADH) for IPA measurement was constructed and evaluated. Read More

    Cosmetically Induced Disorders of the Nail with Update on Contemporary Nail Manicures.
    J Clin Aesthet Dermatol 2016 Apr 1;9(4):39-44. Epub 2016 Apr 1.
    Department of Dermatology and Cutaneous Surgery, University of Miami Leonard M. Miller School of Medicine, Miami, Florida.
    The nail carries a significant cosmetic impact and plays an integral role in the multi-billion dollar salon industry. This review focuses on nail disorders that are induced by nail cosmetics via procedures, equipment, or materials that are intended to beautify or adorn the nail. The authors give specific attention to clinical presentations that are common, novel, and underreported, but may be misdiagnosed easily by the competent dermatologist. Read More

    Safety Assessment of Nitrocellulose and Collodion as Used in Cosmetics.
    Int J Toxicol 2016 Jul;35(1 Suppl):50S-9S
    Former Director, Cosmetic Ingredient Review, Cosmetic Ingredient Review, Washington, DC, USA.
    The Cosmetic Ingredient Review Expert Panel (the Panel) assessed the safety of nitrocellulose and collodion as used in cosmetics, concluding that these ingredients are safe in the present practices of use and concentration in cosmetic formulations. Both ingredients are used almost exclusively in nail product formulations. The maximum concentration of use of nitrocellulose in nail polish and enamels is 22%; for collodion, the maximum reported concentration of use in nail polish and enamel is 14%. Read More

    [Comparison of different nail polish in terms of photoprotective efficacy. Interest of their use as supportive care in patients with cancer].
    Bull Cancer 2016 Jul-Aug;103(7-8):612-21. Epub 2016 May 27.
    Université de Nantes, Nantes Atlantique universités, LPiC, MMS, EA2160, faculty of pharmacy, 9, rue Bias, 44000 Nantes, France. Electronic address:
    Many different chemotherapy drugs including cytotoxics and docetaxel in particular are responsible for side effects involving the nails. To prevent these negative effects, patients are advised to apply nail polish. The aim of this article is to study the photoprotective effect of various products applied in two layers. Read More

    Several cases of undesirable effects caused by methacrylate ultraviolet-curing nail polish for non-professional use.
    Contact Dermatitis 2016 Sep 27;75(3):151-6. Epub 2016 May 27.
    Department of Occupational and Environmental Dermatology, Skåne University Hospital, 205 02, Malmö, Sweden.
    Background: Ultraviolet (UV)-curing nail polishes based on acrylates or methacrylates are currently also available for non-professional use. The Swedish Medical Products Agency recently prohibited one brand of UV-curing polish, because several consumers reported undesirable effects after using it.

    Objectives: To investigate whether consumers with undesirable effects after using the UV-curing nail polish that was later prohibited were contact allergic to the polish and its individual ingredients. Read More

    Simultaneous determination of cosmetics ingredients in nail products by fast gas chromatography with tandem mass spectrometry.
    J Chromatogr A 2016 May 2;1446:134-40. Epub 2016 Apr 2.
    U.S. Food and Drug Administration, Office of Regulatory Science, CFSAN/HFS-717, 5100 Paint Branch Parkway, College Park, MD 20740-3835, USA.
    A rapid and sensitive gas chromatography with tandem mass spectrometry (GC-MS/MS) method has been developed and validated to quantitatively determine cosmetic ingredients, such as toluene, N-methylpyrrolidone, 2,4-dihydroxybenzophenone (benzophenone-1, BP-1), and diethylene glycol dimethacrylate, in nail products. In this procedure, test portions were extracted with acetone, followed by vortexing, sonication, centrifugation, and filtration. During the extraction procedure, BP-1 was derivatized making it amenable to GC-MS analysis, using N,O-​bis(trimethylsilyl)​trifluoroacetamide. Read More

    Changes in Cosmetics Use during Pregnancy and Risk Perception by Women.
    Int J Environ Res Public Health 2016 Mar 30;13(4):383. Epub 2016 Mar 30.
    EA 4681, PEPRADE (Périnatalité, Grossesse, Environnement, PRAtiques médicales et Developement), University of Auvergne, 28 Place Henri-Dunant BP 38, Clermont-Ferrand 63001, France.
    Cosmetic products contain various chemical substances that may be potential carcinogen and endocrine disruptors. Women's changes in cosmetics use during pregnancy and their risk perception of these products have not been extensively investigated. The main objective of this study was to describe the proportion of pregnant women changing cosmetics use and the proportion of non-pregnant women intending to do so if they became pregnant. Read More

    [Cosmetic nail products].
    Ann Dermatol Venereol 2016 May 14;143(5):389-96. Epub 2016 Mar 14.
    Département interhospitalier de dermatologie, CHU Brugmann-HUDERF, CHU Saint-Pierre, 322, rue Haute, 1000 Bruxelles, Belgique.
    Cosmetic embellishment of fingernails involves the use of substance that harden either after the evaporation of solvents (varnishes) or after polymerisation (artificial acrylic nails, gel tips, glue-on artificial nails). Pathological reactions to cosmetics usually occur at a remote site for varnishes, and, most commonly, in situ with polymerising substances. Unvarnished artificial nails do not affect pulse oximetry readings, and in theory, patients are not required to remove them. Read More

    Application of cosmetic nail varnish does not affect the antifungal efficacy of amorolfine 5% nail lacquer in the treatment of distal subungual toenail onychomycosis: results of a randomised active-controlled study and in vitro assays.
    Mycoses 2016 May 11;59(5):319-26. Epub 2016 Feb 11.
    Galderma R & D SNC, Sophia Antipolis, France.
    As onychomycosis is unsightly, this study clinically evaluated whether the antifungal efficacy of amorolfine 5% nail lacquer (NL) was affected by a masking, natural-coloured, cosmetic nail varnish applied 24 h later; in vitro investigations were also performed. Subjects with mild-to-moderate distal subungual toenail onychomycosis were randomised to receive amorolfine 5% NL once weekly with or without cosmetic nail varnish applied 24 h later. After 12-week treatment, antifungal activity of affected toenail clippings was assessed by measurement of zones of inhibition (ZOIs) on Trichophyton mentagrophytes seeded agar plates. Read More

    Evaluation of topical antifungal products in an in vitro onychomycosis model.
    Mycoses 2016 May 9;59(5):327-30. Epub 2016 Feb 9.
    Laboratory of Microbiology, Parasitology and Hygiene (LMPH), Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Antwerp, Belgium.
    Many topical commercial products are currently available for the treatment of onychomycosis. However, limited data are available concerning their antifungal activity. Using an in vitro onychomycosis model, the daily application of seven nail formulations was compared to the antifungal reference drug amorolfine (Loceryl(®) ) and evaluated for inhibitory activity against Trichophyton mentagrophytes using an agar diffusion test. Read More

    Effect of 10% fluoride on the remineralization of dentin in situ.
    J Appl Oral Sci 2015 Nov-Dec;23(6):562-70
    Department of Operative and Preventive Dentistry, University Witten/Herdecke, Witten, Germany.
    Objective The purpose of this randomized, cross-over, in situ study was to determine the remineralization of demineralized dentin specimens after the application of a 10% fluoride (F-) or a 1% chlorhexidine-1% thymol (CHX-thymol) varnish. Material and Methods Twelve individuals without current caries activity wore removable appliances in the lower jaw for a period of four weeks. Each appliance contained four human demineralized dentin specimens fixed on the buccal aspects. Read More

    Risk assessment of allergen metals in cosmetic products.
    J Cosmet Sci 2015 Sep-Oct;66(5):313-23
    Cosmetics are one of the most common reasons for hospital referrals with allergic contact dermatitis. Because of the increased use of cosmetics within the population and an increase in allergy cases, monitoring of heavy metals, especially allergen metals, is crucial. The aim of this study was to investigate the concentration of allergen metals, nickel (Ni), cobalt (Co), and chromium (Cr), in the most commonly used cosmetic products including mascara, eyeliner, eye shadow, lipstick, and nail polish. Read More

    Impact of toothpaste on abrasion of sound and eroded enamel: An in vitro white light interferometer study.
    Am J Dent 2015 Oct;28(5):268-72
    Purpose: To evaluate the influence of brushing using toothpastes marketed under different categories on abrasion of sound and eroded enamel in vitro at nanometer scale using a white light interferometer (WLI).

    Methods: Enamel surface of resin-embedded bovine incisors were fine polished with diamond slurry and divided into testing area (approximately 2 mm x 4 mm) and reference area using a nail varnish. The enamel specimens were randomly assigned to 10 groups (n = 10 each); six of which were subjected to erosive challenge. Read More

    The Association Between Urinary Benzophenone Concentrations and Personal Care Product Use in Korean Adults.
    Arch Environ Contam Toxicol 2016 May 1;70(4):640-6. Epub 2015 Dec 1.
    Food Safety Risk Assessment Division, National Institute of Food and Drug Safety Evaluation, Osong, Chungcheongbuk-do, 361-709, Korea.
    Benzophenone (BP) derivatives are widely used in personal care products (PCPs) for protection from ultraviolet radiation. Because of their broad applications, BP derivatives have been found in various human bodily fluids. In the present study, we investigated the relationship between urinary concentrations of BP derivatives and PCP use in Korean adults. Read More

    Nail polish as a source of exposure to triphenyl phosphate.
    Environ Int 2016 Jan 18;86:45-51. Epub 2015 Oct 18.
    Nicholas School of the Environment, Duke University, Durham, NC, USA. Electronic address:
    Triphenyl phosphate (TPHP) is primarily used as either a flame retardant or plasticizer, and is listed as an ingredient in nail polishes. However, the concentration of TPHP in nail polish and the extent of human exposure following applications have not been previously studied. We measured TPHP in ten different nail polish samples purchased from department stores and pharmacies in 2013-2014. Read More

    Selected Disorders of Skin Appendages--Acne, Alopecia, Hyperhidrosis.
    Med Clin North Am 2015 Nov 4;99(6):1195-211. Epub 2015 Sep 4.
    Division of Dermatology, Department of Medicine, University of Washington, Box 354697, 4225 Roosevelt Way Northeast, 4th Floor, Seattle, WA 98105-6920, USA. Electronic address:
    This article reviewed some of the more common diseases of the skin appendages that are encountered in medicine: hyperhidrosis, acne, AA, FPHL, AGA, and TE. The pathophysiology behind the conditions and their treatments were discussed so that the clinician can make logical therapeutic choices for their affected patients. Read More

    Improved radiocarbon analyses of modern human hair to determine the year-of-death by cross-flow nanofiltered amino acids: common contaminants, implications for isotopic analysis, and recommendations.
    Rapid Commun Mass Spectrom 2015 Oct;29(19):1765-73
    Royal Institute for Cultural Heritage, Jubelpark 1, B-1000, Brussels, Belgium.
    Rationale: In forensic investigation, radiocarbon ((14)C) measurements of human tissues (i.e., nails and hair) can help determine the year-of-death. Read More

    A Study of the Possible Harmful Effects of Cosmetic Beauty Products on Human Health.
    Biol Trace Elem Res 2016 Apr 23;170(2):476-84. Epub 2015 Aug 23.
    Department of Pharmacy, University of Niš, Faculty of Medicine, 81dr Zoran Đinđić Boulevard, Niš, 18000, Serbia.
    The origins of the usage of different substances in beauty, skin, body, hair, and nails care products can be found in ancient times. To achieve better quality and enhance their effects, some additives such as preservatives, stabilizers, mineral pigments, dye, and shine were added to these products. Some of these substances may also have allergic, irritating, and harmful effects on human health. Read More

    Wettability behavior of special microscale ZnO nail-coated mesh films for oil-water separation.
    J Colloid Interface Sci 2015 Nov 18;458:79-86. Epub 2015 Jul 18.
    Research Center for Bioengineering and Sensing Technology, Department of Chemistry & Biological Engineering, University of Science & Technology Beijing, Beijing 100083, China.
    The surface free energy and geometrical structure are two important factors to govern the surface wettability. However, the design and simple synthesis of materials with specific surface free energy and geometrical structure, and their elaborate regulations are still a key challenge. Herein, through one-step thermal evaporation method, we successfully synthesized aligned arrays of highly crystallized ZnO with modulated nail structures on the stainless steel meshes for the first time. Read More

    UV-curable gel formulations: Potential drug carriers for the topical treatment of nail diseases.
    Int J Pharm 2015 Aug 14;492(1-2):177-90. Epub 2015 Jul 14.
    UCL School of Pharmacy, 29-39 Brunswick Square, London, WC1N 1AX, UK. Electronic address:
    Nail diseases are common, cause significant distress and treatments are far from successful. Our aim was to investigate the potential of UV-curable gels - currently used as cosmetics - as topical drug carriers for their treatment. These formulations have a long residence on the nail, which is expected to increase patient compliance and the success of topical therapy. Read More

    In Vitro Nail Penetration of Tavaborole Topical Solution, 5%, Through Nail Polish on Ex Vivo Human Fingernails.
    J Drugs Dermatol 2015 Jul;14(7):675-8
    Background: Onychomycosis is a common infection of the toenails that causes nail thickening and discoloration. The physical appearance of the infected nail can diminish self-image and negatively impact quality of life. Patients may use nail polish to mask the appearance of infected nails. Read More

    Sensory factors affecting female consumers' acceptability of nail polish.
    Int J Cosmet Sci 2015 Dec 14;37(6):642-50. Epub 2015 Jul 14.
    The Sensory Analysis Center, Kansas State University, 1310 Research Park Drive, Manhattan, KS, 66502, U.S.A.
    Objective: The objectives of this study were to determine what sensory factors impact consumers' acceptability of nail polishes, to explore how these sensory factors impact consumers' acceptability of nail polishes, to investigate whether there are any consumer segments according to their overall acceptability on different nail polishes and to scrutinize how the consumer segments are related to the sensory factors.

    Methods: Ninety-eight females participated in a nail polish consumer study at Kansas State University. Eight commercial products belonging to four categories - regular (REG), gel (GEL), flake (FLK) and water-based (WAT) - were evaluated. Read More

    Optimization of an analytical methodology for the simultaneous determination of different classes of ultraviolet filters in cosmetics by pressurized liquid extraction-gas chromatography tandem mass spectrometry.
    J Chromatogr A 2015 Jul 4;1405:12-22. Epub 2015 Jun 4.
    Department of Analytical Chemistry, Nutrition and Food Science, Faculty of Chemistry, Campus Vida, University of Santiago de Compostela, E-15782 Santiago de Compostela, Spain. Electronic address:
    A methodology based on pressurized liquid extraction (PLE) followed by gas chromatography-tandem mass spectrometry (GC-MS/MS) has been developed for the simultaneous analysis of different classes of UV filters including methoxycinnamates, benzophenones, salicylates, p-aminobenzoic acid derivatives, and others in cosmetic products. The extractions were carried out in 1mL extraction cells and the amount of sample extracted was only 100mg. The experimental conditions, including the acetylation of the PLE extracts to improve GC performance, were optimized by means of experimental design tools. Read More

    Photoactive TiO₂ antibacterial coating on surgical external fixation pins for clinical application.
    Int J Nanomedicine 2015 6;10:3367-75. Epub 2015 May 6.
    Laboratory C-Biosenss EA 4676, Clermont-Ferrand University, Université d'Auvergne, Clermont-Ferrand, France.
    External fixation is a method of osteosynthesis currently used in traumatology and orthopedic surgery. Pin tract infection is a common problem in clinical practice. Infection occurs after bacterial colonization of the pin due to its contact with skin and the local environment. Read More

    Screening-level human health risk assessment of toluene and dibutyl phthalate in nail lacquers.
    Food Chem Toxicol 2015 Jul 9;81:46-53. Epub 2015 Apr 9.
    Cardno ChemRisk, LLC 2107 Wilson Boulevard, Suite 800, Arlington, VA 22201, USA.
    Toluene and dibutyl phthalate (DBP) are found in many consumer products, including cosmetics, synthetic fragrances, and nail polish. In 2012, the California Environmental Protection Agency evaluated 25 nail products and found that 83% of the products that claimed to be toluene-free contained toluene at concentrations ranging up to 190,000 ppm, and 14% of the products that claimed to be DBP-free contained DBP at concentrations ranging up to 88,000 ppm. We conducted a preliminary, screening-level analysis of the potential toluene and DBP-related health risks to consumers and professionals based on the medium and maximum concentrations of toluene and DBP presented in the 2012 report and evaluated dermal and inhalation exposure to a salon patron, nail technician, and home user. Read More

    Confocal Raman spectrocopy for the analysis of nail polish evidence.
    Talanta 2015 Jun 25;138:155-62. Epub 2015 Feb 25.
    University Institute of Research in Police Sciences, University of Alcalá, Ctra. Madrid-Barcelona Km. 33.600, 28871 Alcalá de Henares, Madrid, Spain; Department of Analytical Chemistry, Physical Chemistry and Chemical Engineering, Multipurpose Building of Chemistry, University of Alcalá, Ctra. Madrid-Barcelona Km. 33.600, 28871 Alcalá de Henares, Madrid, Spain. Electronic address:
    Nail polishes are cosmetic paints that may be susceptible of forensic analysis offering useful information to assist in a crime reconstruction. Although the nail polish appearance could allow a quick visual identification of the sample, this analysis is subjected to the perception and subjective interpretation of the forensic examiner. The chemical analysis of the nail polishes offers great deal of information not subjected to analyst interpretation. Read More

    Diagnostic applications of nail clippings.
    Dermatol Clin 2015 Apr 24;33(2):289-301. Epub 2015 Feb 24.
    Department of Dermatology, Hospital of the University of Pennsylvania, 3600 Spruce Street, 2 Maloney, Philadelphia, PA 19104, USA; The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA; Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.
    "Nail clipping is a simple technique for diagnosis of several nail unit dermatoses. This article summarizes the practical approach, utility, and histologic findings of a nail clipping in evaluation of onychomycosis, nail unit psoriasis, onychomatricoma, subungual hematoma, melanonychia, and nail cosmetics, and the forensic applications of this easily obtained specimen. It reviews important considerations in optimizing specimen collection, processing methods, and efficacy of special stains in several clinical contexts. Read More


    Metals in cosmetics: implications for human health.
    J Appl Toxicol 2015 Jun 23;35(6):551-72. Epub 2015 Mar 23.
    Department of Toxicology, Medical University of Bialystok, Adama Mickiewicza 2C Street, 15-222, Bialystok, Poland.
    Cosmetics, preparations repeatedly applied directly to the human skin, mucous membranes, hair and nails, should be safe for health, however, recently there has been increasing concern about their safety. Unfortunately, using these products in some cases is related to the occurrence of unfavourable effects resulting from intentional or the accidental presence of chemical substances, including toxic metals. Heavy metals such as lead, mercury, cadmium, arsenic and nickel, as well as aluminium, classified as a light metal, are detected in various types of cosmetics (colour cosmetics, face and body care products, hair cosmetics, herbal cosmetics, etc. Read More

    The effects of picric acid (2,4,6-trinitrophenol) and a bite-deterrent chemical (denatonium benzoate) on autotomy in rats after peripheral nerve lesion.
    Lab Anim (NY) 2015 Apr;44(4):141-5
    1] Research Center for Neural Repair, University of Tehran, Tehran, Iran. [2] Sina Trauma and Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran.
    Denervation of the hind limb is a technique used to study peripheral nerve regeneration. Autotomy or autophagia is an undesirable response to denervation in such studies. Application of a commercially available lotion used to deter nail biting in humans reduced autotomy in rats after denervation but did not completely prevent it. Read More

    The rising trend in allergic contact dermatitis to acrylic nail products.
    Australas J Dermatol 2015 Aug 6;56(3):221-3. Epub 2015 Mar 6.
    Skin & Cancer Foundation Victoria, Melbourne, Victoria, Australia.
    Shellac is a newly available type of long-wearing nail polish, which is becoming increasingly popular. We describe four cases of allergic contact dermatitis (ACD) to acrylates found in Shellac nail products, involving three beauticians and one consumer who purchased the product over the internet. Increasing use of these new acrylic nail products means that dermatologists need to be aware of the possibility of ACD occurring. Read More

    Role of Titanium in the Development of Yellow Nail Syndrome.
    Skin Appendage Disord 2015 Mar 11;1(1):28-30. Epub 2015 Feb 11.
    Department of Dermatology, Weill Cornell/New York Presbyterian, New York, N.Y., USA.
    Yellow nail syndrome (YNS) is characterized by the triad of nail changes, lymphedema and respiratory tract involvement. Several hypotheses have been postulated to explain the findings in YNS including lymphatic drainage abnormalities along with microvasculopathy. The most recent hypothesis, proposed by Berglund and Calmark [Biol Trace Elem Res 2011;143:1-7], suggests a role of titanium dioxide in the development of YNS. Read More

    An Idiopathic Leukonychia Totalis and Leukonychia Partialis Case Report and Review of the Literature.
    Skin Appendage Disord 2015 Mar 27;1(1):38-42. Epub 2015 Mar 27.
    Department of Dermatology, University of Alabama at Birmingham, Birmingham, Ala., USA.
    Leukonychia totalis and leukonychia partialis are rare nail findings characterized by complete or partial whitening of the nail plate. Leukonychia totalis and leukonychia partialis are usually inherited or associated with systemic disease. Here, we report the case of a 25-year-old man with idiopathic acquired leukonychia totalis and leukonychia partialis and review the literature on this topic. Read More

    Patent review on photostability enhancement of avobenzone and its formulations.
    Recent Pat Drug Deliv Formul 2015 ;9(2):121-8
    School of Pharmacy and Technology Management, Mumbai-Agra Road, Bank of Tapi River, Babulde, Shirpur - 425405, Dhule, Maharashtra, India.
    By the virtue of their nature, cosmetic products are used to clean, perfume, change the appearance of the human body's various external parts and maintain them in a good condition. Their main sites of action may be exemplified by the nails, the hair system, the epidermis, the external genital organs and the mucous membranes of the oral cavity. Sunscreen preparations consist of organic chemicals and inorganic materials. Read More

    Worn down nails after acrylic nail removal.
    Dermatol Online J 2015 Jan 15;21(1). Epub 2015 Jan 15.
    University of Miami L. Miller School of Medicine.
    Worn-down nail syndrome is a nail disorder characterized by thinning of the distal nail plate caused by repetitive chemical or mechanical trauma. We present a previously undescribed source of worn-down nail syndrome caused by trauma from nail filing after acrylic nail removal. Read More

    Contact allergy to acrylates and methacrylates in consumers and nail artists - data of the Information Network of Departments of Dermatology, 2004-2013.
    Contact Dermatitis 2015 Apr 15;72(4):224-8. Epub 2015 Jan 15.
    Department of Medical Informatics, Biometry and Epidemiology, University of Erlangen/Nürnberg, 91054, Erlangen, Germany.
    Background: Allergic contact dermatitis caused by (meth)acrylates used in artificial nails is a relevant problem in both nail artists and consumers.

    Objective: To analyse the frequency of this problem in the contact allergy surveillance network Information Network of Departments of Dermatology in 2004-2013, and address possible time trends and patterns of co-sensitization.

    Methods: A retrospective analysis of patch test results with (meth)acrylates, along with clinical and demographic data, was performed. Read More

    Carbon dioxide laser plus topical 5-fluorouracil: a new combination therapeutic modality for acral vitiligo.
    J Cosmet Laser Ther 2015 30;17(4):216-23. Epub 2015 Jan 30.
    Department of Dermatology and Venereology, Faculty of Medicine, Suez Canal University , Ismailia , Egypt.
    Background: Acral vitiligo (AV) is resistant to treatment.

    Aim: To evaluate efficacy and safety of combining carbon dioxide (CO2) laser and 5-fluorouracil (5FU) in treating AV.

    Methods: This study included 68 adult patients with AV. Read More

    [What's new in clinical dermatology?].
    Ann Dermatol Venereol 2014 Dec;141 Suppl 4:S597-609
    Département de dermatologie et allergologie, bâtiment des spécialités médicales, hôpitaux de Brabois, centre hospitalo-universitaire de Nancy, 54500 Vandœuvre-les-Nancy, France. Electronic address:
    Dermatoses have been better characterized as hypochromic vitiligo in subjects with dark skin or the acquired racquet nails associated with hyperparathyroidism. The innate immunity has a central role in the new classification of auto inflammatory diseases, neutrophilic dermatoses, neutrophilic urticaria or pseudo-neutrophilic urticaria. Comorbidities have been studied e. Read More

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