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    Antifungal drug resistance: evolution, mechanisms and impact.
    Curr Opin Microbiol 2018 Mar 12;45:70-76. Epub 2018 Mar 12.
    Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5G 1M1, Canada. Electronic address:
    Microorganisms have a remarkable capacity to evolve resistance to antimicrobial agents, threatening the efficacy of the limited arsenal of antimicrobials and becoming a dire public health crisis. This is of particular concern for fungal pathogens, which cause devastating invasive infections with treatment options limited to only three major classes of antifungal drugs. The paucity of antifungals with clinical utility is in part due to close evolutionary relationships between these eukaryotic pathogens and their human hosts, which limits the unique targets to be exploited therapeutically. Read More

    Improving Anesthesia Safety in Low-Resource Settings.
    Anesth Analg 2018 Apr;126(4):1312-1320
    The safety of anesthesia characteristic of high-income countries today is not matched in low-resource settings with poor infrastructure, shortages of anesthesia providers, essential drugs, equipment, and supplies. Health care is delivered through complex systems. Achieving sustainable widespread improvement globally will require an understanding of how to influence such systems. Read More

    Strengthening the Anesthesia Workforce in Low- and Middle-Income Countries.
    Anesth Analg 2018 Apr;126(4):1291-1297
    From the Department of Anesthesiology, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ontario, Canada.
    The majority of the world's population lacks access to safe, timely, and affordable surgical care. Although there is a health workforce crisis across the board in the poorest countries in the world, anesthesia is disproportionally affected. This article explores some of the key issues that must be tackled to strengthen the anesthesia workforce in low- and lower-middle-income countries. Read More

    [Team training and assessment in mixed reality-based simulated operating room : Current state of research in the field of simulation in spine surgery exemplified by the ATMEOS project].
    Unfallchirurg 2018 Mar 15. Epub 2018 Mar 15.
    Lehrstuhl für Informatikanwendungen in der Medizin & Augmented Reality, Institut für Informatik/I‑16, Technische Universität München, Boltzmannstr. 3, 85748, Garching b. München, Deutschland.
    Surgical simulators are being increasingly used as an attractive alternative to clinical training in addition to conventional animal models and human specimens. Typically, surgical simulation technology is designed for the purpose of teaching technical surgical skills (so-called task trainers). Simulator training in surgery is therefore in general limited to the individual training of the surgeon and disregards the participation of the rest of the surgical team. Read More

    Peritoneal encapsulation syndrome: A case report and literature review.
    Int J Surg Case Rep 2017 9;41:520-523. Epub 2017 Nov 9.
    MBChB, MMed (Surgery), College of Health Sciences, University of Zimbabwe, Parirenyatwa Hospital, Mazowe Street, P O Box A168, Avondale, Harare, Zimbabwe.
    Introduction: Peritoneal encapsulation is an infrequently described congenital anomaly that results in formation of an accessory peritoneal membrane. The case presented below is unique in that it illustrates one of the rare complications of this condition. It is important for clinicians to be aware of this condition and its complications in order to limit potential morbidity and mortality. Read More

    [Addisonian Crisis - Risk Assessment and Appropriate Treatment].
    Dtsch Med Wochenschr 2018 Mar 15;143(6):392-396. Epub 2018 Mar 15.
    An adrenal crisis (Addisonian crisis) is an acute life-threatening complication of adrenal insufficiency. It occurs when hydrocortisone demand is not met by supplementation in the context of an infection - often gastrointestinal, fever, trauma, acute psychological or physical stress. Symptoms of weakness, nausea, muscle/joint pain and drowsiness may develop out of robust health within few hours. Read More

    [Diabetic Ketoacidosis and Hyperosmolar Hyperglycemic State].
    Dtsch Med Wochenschr 2018 Mar 15;143(6):384-391. Epub 2018 Mar 15.
    Background:  Diabetic ketoacidosis and the hyperosmolar hyperglycemic state are the most serious diabetic emergencies. Before the discovery of insulin in 1921 by Banting and Best the diagnosis of type 1 diabetes was fatal ending in diabetic ketoacidosis equivalent to a torturous death. Today, mortality from diabetic ketoacidosis is low at approximately 2 %. Read More

    Real-Time Microscopic Monitoring of Flow, Voltage and Current in the Proton Exchange Membrane Water Electrolyzer.
    Sensors (Basel) 2018 Mar 15;18(3). Epub 2018 Mar 15.
    Department of Mechanical Engineering, Yuan Ze Fuel Cell Center, Yuan Ze University, Taoyuan 320, Taiwan.
    Looking for alternative energy sources has been an inevitable trend since the oil crisis, and close attentioned has been paid to hydrogen energy. The proton exchange membrane (PEM) water electrolyzer is characterized by high energy efficiency, high yield, simple system and low operating temperature. The electrolyzer generates hydrogen from water free of any carbon sources (provided the electrons come from renewable sources such as solar and wind), so it is very clean and completely satisfies the environmental requirement. Read More

    "They Lacked the Right Food": A Brief History of Breastfeeding and the Quest for Social Justice.
    J Hum Lact 2018 Mar 1:890334418757449. Epub 2018 Mar 1.
    1 Department of Social Medicine, Ohio University, Athens, OH, USA.
    In the late 19th-century United States and Europe, infants died at high rates from diarrhea. Physicians and social justice advocates responded to the public health crisis with attempts to clean up the water and cows' milk supplies, as well as social welfare legislation and assorted educational efforts to help mothers better care for their children. Most visible among the educational efforts were breastfeeding campaigns. Read More

    An Economic Evaluation of Preventing Falls Using a New Exercise Program in Institutionalized Elderly.
    J Phys Act Health 2018 Mar 15:1-6. Epub 2018 Mar 15.
    Background: Falls in the elderly represent a public health crisis. Effective prevention programs need to conduct economic analyses. The Move With Balance program showed a 65% reduction in falls in institutionalized elderly. Read More

    Why Crisis Pregnancy Centers Are Legal but Unethical.
    AMA J Ethics 2018 Mar 1;20(1):269-277. Epub 2018 Mar 1.
    A clinical fellow in family planning at the University of North Carolina School of Medicine in Chapel Hill.
    Crisis pregnancy centers are organizations that seek to intercept women with unintended pregnancies who might be considering abortion. Their mission is to prevent abortions by persuading women that adoption or parenting is a better option. They strive to give the impression that they are clinical centers, offering legitimate medical services and advice, yet they are exempt from regulatory, licensure, and credentialing oversight that apply to health care facilities. Read More

    Managing uncertainty: Lessons from volcanic lava disruption of transportation infrastructure in Puna, Hawaii.
    J Emerg Manag 2018 Jan/Feb;16(1):29-40
    Department of Urban and Regional Planning, University of Hawaii at Manoa, Honolulu, Hawaii.
    A recent lava flow in Puna, Hawaii, threatened to close one of the major highways serving the region. This article provides background information on the volcanic hazards and describes events, responses, and challenges associated with managing a complex, long-duration disaster. In addition to the need to better understand geologic hazards and threats, there is a need for timely information and effective response and recovery of transportation infrastructure. Read More

    Remotely Piloted Life-Saving Effort vehicles and emergency management: An analysis on revolutionizing humanitarian assistance in Pakistan.
    J Emerg Manag 2018 Jan/Feb;16(1):7-14
    Canis Technology Solutions (Pvt.) Ltd. Doha, Qatar.
    The majority of the Pakistani public has known little of the unmanned aerial vehicles, also known for their onomatopoeically inspired name "drones," except the fact that it regularly rains Hellfire missiles in Pakistan, claiming the lives of many innocent Pakistanis settled in the western provinces. In actuality, in addition to their destructive capacities, these remotely piloted vehicles have been used since the turn of the century in a variety of live-saving and risk-reducing roles. This research article primarily addresses the third stage of Emergency management-response, with Pakistan being the primary region of research. Read More

    A Reminder From the Devastation Hurricane Maria Left Behind.
    Cureus 2018 Jan 8;10(1):e2038. Epub 2018 Jan 8.
    Medicine, University of Puerto Rico School of Medicine.
    On September 20, 2017, Hurricane Maria hit Puerto Rico, causing an unprecedented humanitarian crisis on a level that none of us have experienced before. The following editorial intends to show a physician's perspective of the impact of this storm on healthcare, particularly in triggering cardiovascular events. Read More

    Co-existence of isodicentric Ph chromosomes and the three-way Ph chromosome variant t(3;9;22)(p21;q34;q11) in a rare case of chronic myeloid leukemia.
    Oncol Lett 2018 Apr 26;15(4):4599-4603. Epub 2018 Jan 26.
    Department of Clinical Laboratory, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China.
    More than 90% of patients with chronic myeloid leukemia (CML) have the chromosomal translocation t(9;22)(q34;q11), while 5-8% of patients have complex variant translocations that have previously been thought not to affect the efficacy of imatinib therapy. The present study reports a patient with CML in B-lymphoid blast crisis who had a rare three-way Philadelphia (Ph) variant t(3;9;22)(p21;q34;q11), in addition to isodicentric Ph chromosomes. The patient was initially treated with imatinib for >2 months with a very poor response. Read More

    Systematic review and meta-analysis of omega-3-fatty acids in elderly patients with depression.
    Nutr Res 2018 Feb 8;50:1-9. Epub 2017 Dec 8.
    Department of Nursing, Keimyung University, Daegu, South Korea. Electronic address:
    One of the typical symptoms of a psychological crisis is depression, an increasing concern in the elderly population. Although omega-3-polyunsaturated fatty acids (PUFAs) are reported to be promising nutrients for treating depression, currently, there are no systematic reviews or meta-analyses of randomized control trials that provide critical evidence regarding the potential benefits of omega-3 fatty acids in elderly patients with depression. This analysis was conducted to provide evidence for the clinical application of omega-3 fatty acids in the treatment of depressive symptoms of elderly subjects older than 65 years. Read More

    The Association Between Dissatisfaction with Debriefing and Post-Traumatic Stress Disorder (PTSD) in Rescue and Recovery Workers for the Oklahoma City Bombing.
    Disaster Med Public Health Prep 2018 Mar 15:1-5. Epub 2018 Mar 15.
    2The Altshuler Center for Education & Research,Metrocare Services,Dallas,Texas.
    Objective: The purpose of this study was to investigate potential association between psychopathology and subjective evaluation of the experience of debriefing in disaster-exposed rescue and recovery workers.

    Methods: Structured diagnostic interviews for DSM-III-R psychiatric disorders were conducted with 166 firefighters who served as rescue and recovery workers for the 1995 Oklahoma City bombing, who categorized their satisfaction with the debriefing on 4 levels. "Very dissatisfied" responses were examined for their association with post-traumatic stress disorder (PTSD) and with PTSD symptom groups. Read More

    A vegetable-induced hemolytic crisis in a G6PD deficient person: a case report.
    BMC Res Notes 2018 Mar 14;11(1):179. Epub 2018 Mar 14.
    Teaching (General) Hospital-Kandy, Kandy, Sri Lanka.
    Background: Hemolysis can occur in people with G6PD deficiency under oxidative stress. Acalypha indica is a tropical plant used as a medicinal plant as well as a vegetable. There are a few reported cases of Acalypha indica ingestion induced hemolysis in G6PD deficient people. Read More

    Poaching and human encroachment reverse recovery of African savannah elephants in south-east Angola despite 14 years of peace.
    PLoS One 2018 14;13(3):e0193469. Epub 2018 Mar 14.
    Department of Environmental Conservation, University of Massachusetts Amherst, Amherst, Massachusetts, United States of America.
    With populations of African savannah elephants (Loxodonta africana) declining across the continent, assessing the status of individual elephant populations is important for conservation. Angola's elephant population represents a key linkage between the larger populations of Namibia and Botswana. Elephants in Angola were decimated during the 1975-2002 Angolan civil war, but a 2005 survey showed that populations were recolonizing former habitats. Read More

    Hypertensive crisis with 2 target organ impairment induced by glycyrrhizin: A case report.
    Medicine (Baltimore) 2018 Mar;97(11):e0073
    Department of Endocrinology and Metabolism.
    Rationale: Glycyrrhizin is the main active component of licorice. Licorice and glycyrrhizin induced hypertension has been widely reported, yet licorice and glycyrrhizin induced hypertensive crisis has been rarely known.

    Patient Concerns: The case of this report was a 47-year-old woman, who took 225 mg of glycyrrhizin daily for 3 years due to primary biliary cholangitis. Read More

    Effect of the economic crisis on the use of health and home care services among Spanish COPD patients.
    Int J Chron Obstruct Pulmon Dis 2018 28;13:725-739. Epub 2018 Feb 28.
    Preventive Medicine and Public Health Teaching and Research Unit, Health Sciences Faculty, Universidad Rey Juan Carlos, Alcorcón, Madrid, Spain.
    Background: Chronic obstructive pulmonary disease (COPD) is a major cause of disability and death worldwide. Consequently, COPD patients are frequent users of health and social resources. Therefore, they are highly vulnerable to decreases in investment in healthcare services. Read More

    Analysis of global prevalence of antibiotic resistance in Acinetobacter baumannii infections disclosed a faster increase in OECD countries.
    Emerg Microbes Infect 2018 Mar 14;7(1):31. Epub 2018 Mar 14.
    Faculty of Health Sciences, University of Macau, Macau SAR, China.
    Acinetobacter baumannii is one of the most challenging nosocomial pathogens due to the emergence and widespread of antibiotic resistance. We aimed to provide the first analysis of global prevalence of antibiotic resistance in A. baumannii infections, by synthesizing data and knowledge through a systematic review. Read More

    Metoclopramide induced pheochromocytoma crisis.
    Am J Emerg Med 2018 Mar 5. Epub 2018 Mar 5.
    Maryland Poison Center, Baltimore, MD, United States; Department of Emergency Medicine, University of Maryland School of Medicine, Baltimore, MD, United States.
    Metoclopramide (MCP) is a commonly used anti-emetic in the emergency department (ED). Its use is generally well tolerated; although infrequent adverse reactions such as extrapyramidal reactions or tardive dyskinesia are reported. However, many ED providers are not familiar with the potentially life-threatening hypertensive emergency that can be precipitated by MCP administration in patients with pheochromocytoma. Read More

    New elephant crisis in Asia-Early warning signs from Myanmar.
    PLoS One 2018 13;13(3):e0194113. Epub 2018 Mar 13.
    Smithsonian Conservation Biology Institute, National Zoological Park, Front Royal, VA, United States of America.
    In the southern Bago Yoma mountain range in Myanmar, Asian elephants are being killed at a disturbing rate. This emerging crisis was identified initially through a telemetry study when 7 of 19 of collared elephants were poached within a year of being fitted with a satellite-GPS collar. Subsequent follow up of ground teams confirmed the human caused death or disappearance of at least 19 elephants, including the seven collared individuals, within a 35 km2 area in less than two years. Read More

    Inherited blood disorders, genetic risk and global public health: framing 'birth defects' as preventable in India.
    Anthropol Med 2018 Apr;25(1):30-49
    a Department of Health Sciences , University of York , York , United Kingdom.
    This paper engages critically with the global assemblage framing sickle cell and thalassaemia disorders as a 'global health crisis'; and the promise of genomics, largely DNA-based carrier/pre-conceptual screening, prenatal diagnosis with a view to terminations, deployed in framing a solution to these historically racialised spectrum of diseases as essentially preventable. Sickle cell and thalassaemia are recessively inherited, potentially life-threatening haemoglobin disorders with significant variation of severity, often needing life-long treatment. I argue that the re-classification of inherited blood disorders (IBDs) under 'prevention and management of birth defects' by the WHO in 2010 can be read as an ethical moment within the 'globalising turn' of IBDs and the use of genomics in addressing structural inequalities underpinning health in low- and middle-income countries. Read More

    Challenges and Opportunities in Disease Forecasting in Outbreak Settings: A Case Study of Measles in Lola Prefecture, Guinea.
    Am J Trop Med Hyg 2018 Mar 12. Epub 2018 Mar 12.
    Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
    We report on and evaluate the process and findings of a real-time modeling exercise in response to an outbreak of measles in Lola prefecture, Guinea, in early 2015 in the wake of the Ebola crisis. Multiple statistical methods for the estimation of the size of the susceptible (i.e. Read More

    The Psychophysiological Determinants of Pacing Behaviour and Performance During Prolonged Endurance Exercise: A Performance Level and Competition Outcome Comparison.
    Sports Med 2018 Mar 12. Epub 2018 Mar 12.
    Division of Exercise Science and Sports Medicine, Department of Human Biology, University of Cape Town, Newlands, 7725, South Africa.
    Introduction: A three-dimensional framework of centrally regulated and goal-directed exercise behaviour emphasised the integration of distinct sensory-discriminatory, affective-motivational and cognitive-evaluative dimensions that underpin perceived fatigability. This study aimed to capture the complex interdependencies and temporal dynamics in these processes, their interrelations with observed pacing behaviour, performance and biochemical variables as well as their performance level- and competition outcome-dependent variances.

    Methods: Twenty-three cyclists of distinct performance level categories engaged in individual and head-to-head competition time trials against a performance-matched opponent. Read More

    Adult Sickle Cell Anaemia Patients in Bone Pain Crisis have Elevated Pro-Inflammatory Cytokines.
    Mediterr J Hematol Infect Dis 2018 1;10(1):e2018017. Epub 2018 Mar 1.
    Department of Haematology, University College Hospital, Ibadan, Nigeria.
    Background And Objectives: Inflammatory markers that influence bone pain crisis (BPC) and other complications of sickle cell anaemia (SCA) are numerous and play various roles. This study determined the plasma levels of tumour necrosis factor (TNF) - α, interleukin - 8 (IL-8), and endothelin - 1 (ET-1) in adult SCA patients during BPC and in steady state. In addition, the plasma levels of these cytokines were correlated with the severity of BPC of the patients. Read More

    Association of thePolymorphism (Val16Ala) and SOD Activity with Vaso-occlusive Crisis and Acute Splenic Sequestration in Children with Sickle Cell Anemia.
    Mediterr J Hematol Infect Dis 2018 21;10(1):e2018012. Epub 2018 Feb 21.
    Biological Science Institute, University of Pernambuco Pernambuco, Brazil.
    The SOD2 polymorphism Val16Ala T→C influences the antioxidative response. This study investigated the association of the SOD2 polymorphism and superoxide dismutase (SOD) activity with the vaso-occlusive crisis (VOC) and acute splenic sequestration (ASS) in children with sickle cell anemia (SCA). One hundred ninety-five children with SCA aged 1-9 years old were analyzed. Read More

    Crisis or self-correction: Rethinking media narratives about the well-being of science.
    Proc Natl Acad Sci U S A 2018 Mar;115(11):2620-2627
    Annenberg School for Communication, University of Pennsylvania, Philadelphia, PA 19104;
    After documenting the existence and exploring some implications of three alternative news narratives about science and its challenges, this essay outlines ways in which those who communicate science can more accurately convey its investigatory process, self-correcting norms, and remedial actions, without in the process legitimizing an unwarranted "science is broken/in crisis" narrative. The three storylines are: () quest discovery, which features scientists producing knowledge through an honorable journey; () counterfeit quest discovery, which centers on an individual or group of scientists producing a spurious finding through a dishonorable one; and () a systemic problem structure, which suggests that some of the practices that protect science are broken, or worse, that science is no longer self-correcting or in crisis. Read More

    Opinion: Is science really facing a reproducibility crisis, and do we need it to?
    Proc Natl Acad Sci U S A 2018 Mar;115(11):2628-2631
    Department of Methodology, London School of Economics and Political Science, London WC2A 2AE, United Kingdom
    Efforts to improve the reproducibility and integrity of science are typically justified by a narrative of crisis, according to which most published results are unreliable due to growing problems with research and publication practices. This article provides an overview of recent evidence suggesting that this narrative is mistaken, and argues that a narrative of epochal changes and empowerment of scientists would be more accurate, inspiring, and compelling. Read More

    Syrian refugees in Greece: experience with violence, mental health status, and access to information during the journey and while in Greece.
    BMC Med 2018 03 13;16(1):40. Epub 2018 Mar 13.
    Epicentre, Paris, France.
    Background: Since 2015, Europe has been facing an unprecedented arrival of refugees and migrants: more than one million people entered via land and sea routes. During their travels, refugees and migrants often face harsh conditions, forced detention, and violence in transit countries. However, there is a lack of epidemiological quantitative evidence on their experiences and the mental health problems they face during their displacement. Read More

    Prevention Diaries.
    Health Promot Pract 2018 Mar 1:1524839918759527. Epub 2018 Mar 1.
    1 Los Angeles County Department of Public Health, Los Angeles, CA, USA.
    Disease prevention is an effective means for improving health outcomes and reducing the cost burden of chronic diseases. Prevention Diaries is a collection of short accounts and learnings with the goal of making the case for prevention as a transformative tool to drive health and social change. The book provides insight from the field and outlines why prevention is the solution to many social challenges and provides innovative ideas that are needed to advance the prevention agenda. Read More

    A dynamic analysis of S&P 500, FTSE 100 and EURO STOXX 50 indices under different exchange rates.
    PLoS One 2018 12;13(3):e0194067. Epub 2018 Mar 12.
    Institute for Risk and Uncertainty, University of Liverpool, Chadwick Building, L69 7ZF, Liverpool, United Kingdom.
    In this study, we assess the dynamic evolution of short-term correlation, long-term cointegration and Error Correction Model (hereafter referred to as ECM)-based long-term Granger causality between each pair of US, UK, and Eurozone stock markets from 1980 to 2015 using the rolling-window technique. A comparative analysis of pairwise dynamic integration and causality of stock markets, measured in common and domestic currency terms, is conducted to evaluate comprehensively how exchange rate fluctuations affect the time-varying integration among the S&P 500, FTSE 100 and EURO STOXX 50 indices. The results obtained show that the dynamic correlation, cointegration and ECM-based long-run Granger causality vary significantly over the whole sample period. Read More

    Housing versus treatment first for supportive housing participants with substance use disorders: A comparison of housing and public service use outcomes.
    Subst Abus 2018 Mar 12:1-24. Epub 2018 Mar 12.
    a Bureau of Epidemiology Services, New York City Department of Health and Mental Hygiene , Queens , New York , USA.
    Background: Homeless persons with substance use disorders (SUD) have high disease risk, poor access to healthcare, and are frequent users of Medicaid and other social services. Low-demand supportive housing with no prerequisites for treatment or sobriety has been shown to improve housing stability and decrease public service use for chronically homeless persons with serious mental illness (SMI) and chronic medical conditions. The impact of low-demand housing on individuals with SUD but without co-occurring SMI has been little studied. Read More

    [Depression in adolescents and multiculturality : a multifactorial analysis of psychological suffering inside a family in crisis].
    Rev Med Brux 2018 ;39(1):41-46
    Centre Ados, L'Equipe A.S.B.L., ULB.
    The complexity of depressive diagnosis and other forms of expression of psychological suffering during adolescence explain why particular caution is required. The medico-psycho-social determinants of teenager's mental health enjoin us to support a holistic analysis of these situations. Different analysis spectra - symptomatic, environnemental, anthropological, cultural - allow us to understand a situation at different levels of interpretation. Read More

    World TB Day 2018: The Challenge of Drug Resistant Tuberculosis.
    F1000Res 2018 22;7:217. Epub 2018 Feb 22.
    TB Centre, London School of Hygiene & Tropical Medicine, London, UK.
    On 24th March, the world commemorates the day in 1882 when Dr Robert Koch announced his discovery of(MTB). Over 130 years later, tuberculosis (TB) continues to affect individuals, communities, and entire health systems and economies. Koch unsuccessfully tried to 'cure' TB, and despite major advances in other areas of medicine, control of TB remains elusive- in 2016 TB was the leading infectious cause of death. Read More

    Emotional reaction evaluation provoked by the vestibular caloric test through physiological variables monitoring.
    Acta Otorrinolaringol Esp 2018 Mar 8. Epub 2018 Mar 8.
    Clínica ORL Barona y Asociados, Hospital Casa de Salud, Valencia, España. Electronic address:
    Introduction And Objectives: The emotional evaluation of the causes of vertigo is made using the clinical records and several subjective questionnaires. The aim of the present study is to evaluate the emotional response objectively, in normal subjects, during an induced vertigo crisis.

    Material And Method: A caloric vestibular test with cold water was performed on 30 healthy subjects. Read More

    Perioperative Management of Pregnant Women With Idiopathic Pulmonary Arterial Hypertension: An Observational Case Series Study From China.
    J Cardiothorac Vasc Anesth 2018 Mar 7. Epub 2018 Mar 7.
    Department of Anesthesiology, Jewish Hospital, Department of Anesthesiology and Perioperative Medicine, University of Louisville, Louisville, KY. Electronic address:
    Objectives: The mortality of pregnant women with idiopathic pulmonary arterial hypertension (PAH) is very high. There are limited data on the management of idiopathic PAH during pregnancy. The authors aimed to examine systematically the characteristics of parturient women with idiopathic PAH, to explore the adverse effects of idiopathic PAH on pregnancy outcomes, and to report the multidisciplinary perioperative management strategy from the largest comprehensive cardiac hospital in China. Read More

    The Far Right Challenge Comment on "The Rise of Post-truth Populism in Pluralist Liberal Democracies: Challenges for Health Policy".
    Int J Health Policy Manag 2017 Jul 11;7(2):195-198. Epub 2017 Jul 11.
    University of Reading, Reading, UK.
    Speed and Mannion make a good case that the rise of populism poses significant challenges for health policy. This commentary suggests that the link between populism and health policy should be further nuanced in four ways. First, a deconstruction of the term populism itself and a focus on the far right dimension of populist politics; second, a focus on the supply side and more specifically the question of nationalism and the 'national preference'; third, the dynamics of party competition during economic crisis; and fourth the question of policy, and more specifically the extent to which certain labour market policies are able to mediate demand for the far right. Read More

    Treatment with medium chain fatty acids milk of CD36-deficient preschool children.
    Nutrition 2017 Nov 29;50:45-48. Epub 2017 Nov 29.
    Department of Clinical Laboratory Medicine, Juntendo University School of Medicine, Tokyo, Japan.
    Objective: CD36 deficiency is characterized by limited cellular long chain fatty acid uptake in the skeletal and cardiac muscles and often causes energy crisis in these muscles. However, suitable treatment for CD36 deficiency remains to be established. The aim of this study was to evaluate the clinical and metabolic effects of medium chain triacylglycerols (MCTs) in two CD36-deficient preschool children who often developed fasting hypoglycemia and exercise-induced myalgia. Read More

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