53,111 results match your criteria Myxedema Coma or Crisis


San Antonio refugees: Their demographics, healthcare profiles, and how to better serve them.

PLoS One 2019 19;14(2):e0211930. Epub 2019 Feb 19.

The San Antonio Refugee Health Clinic, The Student-Faculty Collaborative Practices Program, The Center for Medical Humanities and Ethics, The Long School of Medicine, The University of Texas Health San Antonio, San Antonio, Texas, United States of America.

Objective: The recent refugee crisis has resulted in the largest burden of displacement in history, with the US being the top resettlement country since 1975. Texas welcomed the second most US-bound refugees in 2016, with a large percentage arriving in San Antonio. Yet, the composition of the San Antonio refugees has not been described and their healthcare needs remain ill-defined. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0211930PLOS
February 2019

Why go to the emergency department? Perspectives from persons with borderline personality disorder.

Int J Ment Health Nurs 2019 Feb 18. Epub 2019 Feb 18.

Faculty of Health Sciences, School of Nursing, University of Ottawa, Ottawa, Ontario, Canada.

Through this qualitative study, we explored frequent emergency department use by persons with borderline personality disorder from their perspective. Interpretive description guided the study design, and data were collected through interviews with six individuals diagnosed with borderline personality disorder who had at least 12 emergency department visits for reasons related to their mental illness within a 1-year timeframe. Using thematic data analysis, we articulate the participants' experiences through two broad themes: cyclic nature of emergency department use and coping skills and strategies. Read More

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http://dx.doi.org/10.1111/inm.12580DOI Listing
February 2019

Carers of people from LGBTQ communities interactions with mental health service providers: Conflict and safety.

Int J Ment Health Nurs 2019 Feb 18. Epub 2019 Feb 18.

Carers Victoria, Melbourne, Victoria, Australia.

This exploratory study examines the experiences of informal/family carers of people from LGBTQ communities living with mental illness, or experiencing a mental health crisis, in relation to conflict and safety in their interactions with mental health service providers. Carers were surveyed to gain an understanding of their experiences of services. The data were analysed according to the six main originating domains in the Safewards model where conflict may arise as well as the nature of the activity in the domain with the addition of new categories of 'carer characteristics' and 'carer modifiers'. Read More

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http://dx.doi.org/10.1111/inm.12581DOI Listing
February 2019

Preparedness for chemical crisis situations: experiences from European medical response exercises.

Eur Rev Med Pharmacol Sci 2019 Feb;23(3):1239-1247

Comprehensive Defence Division, Norwegian Defence Research Establishment, Kjeller, Norway.

Objective: This study investigated how European first responders and hospital personnel, along with CBRN experts, approach an overwhelming surge situation after a chemical incident. Surge capacity and capability bottlenecks were discussed.

Materials And Methods: Two chemical warfare agent (CWA) scenarios were developed: in the first, a nerve agent was released indoors; in the second, there was an outdoor explosion containing a blister agent. Read More

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http://dx.doi.org/10.26355/eurrev_201902_17017DOI Listing
February 2019

[Group work in the context of our time].

Vertex 2018 Jul;XXIX(140):307-312

Hospital Escuela de Salud Mental de San Luis.

This work is part of the daily work carried out by the Hospital School of Mental Health of the Province of San Luis, Argentina, and it is our interest to briefly describe how it has been transformed into what it is today, to then understand a possible way of approaching situations of catastrophe and crisis. From this framework of institutional work we want to show that groupness arises as a need to accompany the interdisciplinary teams in decision-making, creating an open space for collective construction: the institution responsible for responding to the problems that the community presents; the institution that previously denied the existence of certain problems now finds new alternatives, deepens in the knowledge of them and passes from descriptive diagnoses to situational diagnoses. We use a group device based on groupal theories and we think that the therapeutic team and the institutions are considered a group. Read More

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Effects of Ageing on the Mitochondrial Genome in Rat Vestibular Organs.

Curr Aging Sci 2018 ;11(2):108-117

Neurobiology of Ageing and Dementia Laboratory, School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, University of Newcastle, Callaghan, NSW 2308, Australia.

Background: Deterioration in vestibular function occurs with ageing and is linked to age-related falls. Sensory hair cells located in the inner ear vestibular labyrinth are critical to vestibular function. Vestibular hair cells rely predominantly on oxidative phosphorylation (OXPHOS) for energy production and contain numerous mitochondria. Read More

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http://dx.doi.org/10.2174/1874609811666180830143358DOI Listing
January 2018

Prospective implementation of a nonopioid protocol for patients undergoing robot-assisted radical cystectomy with extracorporeal urinary diversion.

Urol Oncol 2019 Feb 15. Epub 2019 Feb 15.

Department of Urology, Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address:

Objectives: To evaluate the feasibility and outcomes of a nonopioid (NOP) perioperative pain management protocol for patients undergoing robot-assisted radical cystectomy (RARC).

Materials And Methods: We prospectively included 52 consecutive patients undergoing RARC at our institution for bladder cancer. Patients received a multimodal pain management protocol, including a combination of nonopioid pain medications and regional anesthesia. Read More

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http://dx.doi.org/10.1016/j.urolonc.2019.02.002DOI Listing
February 2019

Reports of rationing from the neglected realm of capital investment: Responses to resource constraint in the English National Health Service.

Soc Sci Med 2019 Feb 13;225:1-8. Epub 2019 Feb 13.

Health Services Management Centre, University of Birmingham, 40 Edgbaston Park Rd, Birmingham, UK. Electronic address:

Health systems around the world face financial pressures that can affect sustainability and patient outcomes, and there is a vast literature devoted to the allocation of scarce health care resources. Capital spending - for example on estates, equipment and information technology - is an important but often neglected area of this literature. This study explores the constraints on the allocation of capital budgets in health care, before addressing the question: what is the role of priority setting and rationing in responses to these constraints? The paper presents findings from interviews conducted with senior finance professionals in 30 National Health Service local provider organisations across England. Read More

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http://dx.doi.org/10.1016/j.socscimed.2019.02.015DOI Listing
February 2019

If this is true, what does it imply? How end-user antibody validation facilitates insights into biology and disease.

Asian J Urol 2019 Jan 12;6(1):10-25. Epub 2018 Dec 12.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Antibodies are employed ubiquitously in biomedical sciences, including for diagnostics and therapeutics. One of the most important uses is for immunohistochemical (IHC) staining, a process that has been improving and evolving over decades. IHC is useful when properly employed, yet misuse of the method is widespread and contributes to the "reproducibility crisis" in science. Read More

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http://dx.doi.org/10.1016/j.ajur.2018.11.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363603PMC
January 2019

Family-related Disparities in College Enrollment across the Great Recession.

Sociol Perspect 2018 Oct 28;61(5):689-710. Epub 2018 Feb 28.

University of Texas at Austin, Austin, TX, USA.

The economic crisis of the Great Recession in the late 2000s had implications for the intergenerational transmission of inequality within families. Studying patterns of college enrollment across the Great Recession among U.S. Read More

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http://dx.doi.org/10.1177/0731121418760542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372127PMC
October 2018

Jumping in and Out of the Dirty Water… Learning from Stories while Doing Social Science.

Authors:
Keri K Stephens

Health Commun 2019 Feb 18:1-4. Epub 2019 Feb 18.

a Department of Communication Studies, Organizational Communication and Technology , The University of Texas at Austin.

The pursuit of knowledge surrounding health-related issues during disasters, emergencies, and crises, can be delicate and challenging. Social scientists use a host of research methods to design and execute studies with the goal of making intellectual contributions. During extended field work following Hurricane Harvey in the Greater Houston area, our team collected data - interviews, observations, and private social media - from citizens, emergency responders, and volunteer rescuers. Read More

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http://dx.doi.org/10.1080/10410236.2019.1580995DOI Listing
February 2019

Design, Performance, and Application of Thermoelectric Nanogenerators.

Small 2019 Feb 18:e1805241. Epub 2019 Feb 18.

CAS Center for Excellence in Nanoscience, Beijing Key Laboratory of Micro-Nano Energy and Sensor, Beijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, Beijing, 100083, P. R. China.

Thermal energy harvesting from the ambient environment through thermoelectric nanogenerators (TEGs) is an ideal way to realize self-powered operation of electronics, and even relieve the energy crisis and environmental degradation. As one of the most significant energy-related technologies, TEGs have exhibited excellent thermoelectric performance and played an increasingly important role in harvesting and converting heat into electric energy, gradually becoming one of the hot research fields. Here, the development of TEGs including materials optimization, structural designs, and potential applications, even the opportunities, challenges, and the future development direction, is analyzed and summarized. Read More

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http://dx.doi.org/10.1002/smll.201805241DOI Listing
February 2019
1 Read

Selected Legal Aspects of Donation After Circulatory Death in Poland.

Ann Transplant 2019 Feb 18;24:93-99. Epub 2019 Feb 18.

Department Nephrology, Dialysis, and Internal Diseases, Warsaw Medical University, Warsaw, Poland.

Organ transplantation is one of the most critical ethical topics in law and medicine and a matter of debate in various countries. Lack of organs for engraftment to meet the existing demand has resulted in a substantial crisis due to organ shortage and a rise in the critical conditions of certain waitlisted patients, as well as increased mortality of patients while waiting. Organ shortages for transplantation raised the issue of procurement of organs not only from living donors and cadaveric donors after brain death, but also after circulatory death. Read More

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http://dx.doi.org/10.12659/AOT.912567DOI Listing
February 2019

Acute Pulmonary Hypertension Crisis after Adalimumab Reduction in Rheumatoid Vasculitis.

Intern Med 2019 15;58(4):593-601. Epub 2019 Feb 15.

Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Japan.

Rheumatoid vasculitis is a rare etiology for pulmonary hypertension (PH) in patients with connective tissue disease. We encountered a case of acute PH crisis in a case with rheumatoid vasculitis eight months after undergoing adalimumab reduction. Since no repetition of arthralgia occurred after the adalimumab reduction, we decided to not increase the dose of adalimumab. Read More

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http://dx.doi.org/10.2169/internalmedicine.1143-18DOI Listing
February 2019

Influenza-Related Communication and Community Mitigation Strategies: Results From the 2015 Pandemic Influenza Readiness Assessment.

Health Promot Pract 2019 Feb 17:1524839919826582. Epub 2019 Feb 17.

1 Centers for Disease Control and Prevention, Atlanta, GA, USA.

Emergence of a novel infectious disease, such as pandemic influenza, is the one global crisis most likely to affect the greatest number of people worldwide. Because of the potentially severe and contagious nature of influenza, a rapid multifaceted pandemic response, which includes nonpharmaceutical interventions (NPIs) and effective strategies for communication with the public are essential for a timely response and mitigating the spread of disease. A web-based questionnaire was administered via email in July 2015 to 62 Public Health Emergency Preparedness (PHEP) directors across jurisdictions that receive funding through the Centers for Disease Control and Prevention PHEP cooperative agreement. Read More

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http://dx.doi.org/10.1177/1524839919826582DOI Listing
February 2019

Economic sanctions threaten population health: the case of Iran.

Public Health 2019 Feb 13;169:10-13. Epub 2019 Feb 13.

Department of Finance, NEOMA Business School, France.

Objective: The aim of the study is to review evidence of the negative consequences of international economic sanctions on population health in Iran and pathways via which the sanctions affect health.

Study Design: This is a narrative review.

Methods: Data from the World Bank and the Central Bank of Iran were gathered to clarify economic consequences of sanctions. Read More

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http://dx.doi.org/10.1016/j.puhe.2019.01.006DOI Listing
February 2019

Pulmonary arterial hypertension in adults with systemic right ventricles referred for cardiac transplantation.

Clin Transplant 2019 Feb 15:e13496. Epub 2019 Feb 15.

Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

Background: Systemic right ventricular [RV] failure may progress necessitating referral for orthotropic heart transplantation [OHT]. Pulmonary hypertension [PH] frequently coexists in adult congenital heart disease and can complicate the assessment for OHT.

Methods: Single-center case series of six patients [median age 34. Read More

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http://doi.wiley.com/10.1111/ctr.13496
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http://dx.doi.org/10.1111/ctr.13496DOI Listing
February 2019
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Design and construction of Z-scheme BiS/nitrogen-doped graphene quantum dots: Boosted photoelectric conversion efficiency for high-performance photoelectrochemical aptasensing of sulfadimethoxine.

Biosens Bioelectron 2019 Feb 5;130:230-235. Epub 2019 Feb 5.

Key Laboratory of Modern Agriculture Equipment and Technology, School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang 212013, PR China; Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, PR China. Electronic address:

Rational design and fabrication of Z-scheme visible-light-driven photoactive materials have drawn much attention owing to their great potential in handling environment and energy crisis. In this work, Z-scheme BiS/nitrogen-doped graphene quantum dots (NGQDs) with superior photoelectric conversion efficiency were designed and fabricated, which demonstrated enhanced photoactivity compared with BiS owing to the improved separation efficiency of photogenerated electron and hole pairs. The emphasis was put on designing Z-scheme BiS/NGQDs, and then the mechanism of Z-scheme charge transfer mode was verified by the electron spin resonance (ESR) technique. Read More

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http://dx.doi.org/10.1016/j.bios.2019.01.058DOI Listing
February 2019
6.409 Impact Factor

Application of Mass Spectrometry-Based Immunoassays for the Species- and Tissue-Specific Quantification of Banned Processed Animal Proteins in Feeds.

Anal Chem 2019 Feb 15. Epub 2019 Feb 15.

Processed Animal Proteins (PAPs) are considered as a sustainable protein source to improve the nutritional profile of feed for livestock and aquaculture. However, the use of these proteins is strongly regulated since the bovine spongiform encepha-lopathy (BSE) crisis. The reintroduction of non-ruminant PAPs for the use in aquaculture in 2013 has driven the need for alternative analytical methods to determine the species origin as well as the tissue source (legal or not). Read More

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http://pubs.acs.org/doi/10.1021/acs.analchem.8b04652
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http://dx.doi.org/10.1021/acs.analchem.8b04652DOI Listing
February 2019
4 Reads

So the doctor is burned out: What does it mean for patient care?

Acad Emerg Med 2019 Feb 15. Epub 2019 Feb 15.

Department of Emergency Medicine, Stanford University School of Medicine, 900 Welch Road, Suite 350, Palo Alto, CA, 94304.

The current state of physician burnout has become an increasingly popular topic of discussion and concern. Depending on how it is defined and measured by researchers, the prevalence of physician burnout ranges anywhere from 0 to 80%. Emergency medicine is often cited as the specialty with some of the highest reported levels of physician burnout. Read More

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http://dx.doi.org/10.1111/acem.13714DOI Listing
February 2019

Team planning discussion and clinical performance: a prospective, randomised, controlled simulation trial.

Anaesthesia 2019 Feb 15. Epub 2019 Feb 15.

Health Services and Performance Research laboratory (EA 7425), Claude Bernard Lyon 1 University, Lyon, France.

Planning held before emergency management of a critical situation might be an invaluable asset for optimising team preparation. The purpose of this study was to investigate whether a brief planning discussion improved team performance in a simulated critical care situation. Forty-four pairs of trainees in anaesthesia and intensive care were randomly allocated to either an intervention or control group before participating in a standardised simulated scenario. Read More

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http://dx.doi.org/10.1111/anae.14602DOI Listing
February 2019

A Population Health Approach to America's Opioid Epidemic.

Orthop Nurs 2019 Feb 13. Epub 2019 Feb 13.

Susan Salmond, EdD, RN, ANEF, FAAN, Executive Vice Dean and Professor, School of Nursing, Rutgers, The State University of New Jersey, Newark, NJ, and Research Editor for Orthopaedic Nursing. Virginia Allread, MPH, Executive Assistant, School of Nursing, Rutgers, The State University of New Jersey, Newark, NJ.

The United States is in the midst of a nationwide public health emergency: an epidemic of opioid misuse and abuse that has been called the deadliest drug crisis in American history. This article reviews the current status of the opioid epidemic, the trends over the last 30-40 years that may have contributed to the epidemic, and a population health approach to addressing the epidemic. The epidemic is conceptualized from a population health perspective-an upstream and midstream perspective focusing on prevention and a downstream perspective targeting access to evidence-based interventions and maximizing health whether using or abstaining. Read More

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http://dx.doi.org/10.1097/NOR.0000000000000521DOI Listing
February 2019

Clinical features of systemic sclerosis patients with anti-RNA polymerase III antibody in a single centre in Spain.

Clin Exp Rheumatol 2019 Feb 11. Epub 2019 Feb 11.

Unit of Systemic Autoimmune Diseases, Institut de Recerca Vall d'Hebron, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Spain.

Objectives: To evaluate the clinical features and survival of patients with positive anti-RNA polymerase III (anti-RNAP III) in a Spanish single centre.

Methods: We analysed 221 patients with SSc according to LeRoy and Medsger criteria. Twenty-six patients with positivity for anti-RNAP III antibodies were compared with 195 negative patients. Read More

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February 2019

At-a-glance - The impact of poisoning-related mortality on life expectancy at birth in Canada, 2000 to 2016.

Health Promot Chronic Dis Prev Can 2019 Feb;39(2):56-60

Public Health Agency of Canada, Ottawa, Ontario, Canada.

Increases in opioid-related mortality have contributed to declines in life expectancy at birth in the United States and British Columbia. Canadian national mortality data from 2000 to 2016 were analyzed to determine the contribution of poisoning-related mortality to changes in life expectancy at birth by age group and sex. From 2000 to 2016, life expectancy at birth increased by almost three years; however, mortality due to unintentional poisonings, including those involving opioids, curbed this increase by 0. Read More

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http://dx.doi.org/10.24095/hpcdp.39.2.03DOI Listing
February 2019

Hypercalcaemic Crisis Due to Primary Hyperparathyroidism: Report of Two Cases.

J Crit Care Med (Targu Mures) 2019 Jan 4;5(1):34-39. Epub 2019 Feb 4.

University of Medicine, Pharmacy, Sciences and Technology of Târgu Mureş, Romania.

Introduction: A hypercalcaemic crisis, also called para thyrotoxicosis, hyper parathyroid crisis or parathyroid storm, is a complication of primary hyperparathyroidism (PHPT) and an endocrinology emergency that can have dramatic or even fatal consequences if it is not recognised and treated in time.

Case Presentation: Two cases presented in the emergency department with critical hypercalcaemic symptoms and severe elevation of serum calcium and parathyroid hormone levels, consistent with a hypercalcaemic crisis. The first case, a 16-year-old female patient, had imaging data that highlighted a single right inferior parathyroid adenoma and a targeted surgical approach was used. Read More

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http://dx.doi.org/10.2478/jccm-2019-0004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369571PMC
January 2019

Evaluation of the Psychiatric Decisions Unit (PDU): effect on emergency department presentations and psychiatric inpatient admissions.

Postgrad Med J 2019 Feb 14. Epub 2019 Feb 14.

Department of Liaison Psychiatry, Birmingham and Solihull Mental Health NHS Foundation Trust, Birmingham, UK

Background: Busy emergency departments (EDs) are not the optimum environment for assessment of patients in mental health crisis. The Psychiatric Decisions Unit (PDU) was developed by the Birmingham and Solihull Mental Health Foundation Trust as an enhanced assessment service to ensure patients in mental health crisis receive optimal care.

Aims: To evaluate the activities of the PDU and its impact on the frequency of ED presentations and inpatient admissions, and to explore patient satisfaction. Read More

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http://dx.doi.org/10.1136/postgradmedj-2018-135788DOI Listing
February 2019

The opioid crisis.

Nurs Outlook 2019 Jan - Feb;67(1):3-5

Global Mental Health Consultant; Psychotherapist in private practice, Health and Aging Policy Fellow 2016-2017, Professor Emerita, Meyers College of Nursing, New York University.

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http://dx.doi.org/10.1016/j.outlook.2018.12.016DOI Listing
February 2019

The hemostasis system in children with hereditary spherocytosis.

Thromb Res 2019 Feb 5;176:11-17. Epub 2019 Feb 5.

Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia; Pirogov Russian National Research Medical University, Moscow, Russia.

Introduction: Patients with hereditary spherocytosis (HS) are characterized by having an increased risk for thrombosis. An early manifestation of thrombotic complications can occur even in childhood, especially after surgery. Hypercoagulability can be associated with hemolytic crises. Read More

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http://dx.doi.org/10.1016/j.thromres.2019.02.004DOI Listing
February 2019

Cocatalysts for Selective Photoreduction of CO into Solar Fuels.

Chem Rev 2019 Feb 14. Epub 2019 Feb 14.

Department of Chemistry , University of Missouri-Kansas City , Kansas City , Missouri 64110 , United States.

Photoreduction of CO into sustainable and green solar fuels is generally believed to be an appealing solution to simultaneously overcome both environmental problems and energy crisis. The low selectivity of challenging multi-electron CO photoreduction reactions makes it one of the holy grails in heterogeneous photocatalysis. This Review highlights the important roles of cocatalysts in selective photocatalytic CO reduction into solar fuels using semiconductor catalysts. Read More

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http://dx.doi.org/10.1021/acs.chemrev.8b00400DOI Listing
February 2019
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The CORE service improvement programme for mental health crisis resolution teams: results from a cluster-randomised trial.

Br J Psychiatry 2019 Feb 14:1-9. Epub 2019 Feb 14.

Professor of Social and Community Psychiatry,Division of Psychiatry,University College London; and St Pancras Hospital,Camden and Islington NHS Foundation Trust,UK.

Background: Crisis resolution teams (CRTs) offer brief, intensive home treatment for people experiencing mental health crisis. CRT implementation is highly variable; positive trial outcomes have not been reproduced in scaled-up CRT care.AimsTo evaluate a 1-year programme to improve CRTs' model fidelity in a non-masked, cluster-randomised trial (part of the Crisis team Optimisation and RElapse prevention (CORE) research programme, trial registration number: ISRCTN47185233). Read More

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http://dx.doi.org/10.1192/bjp.2019.21DOI Listing
February 2019
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Seeking Formula for Misinformation Treatment in Public Health Crises: The Effects of Corrective Information Type and Source.

Health Commun 2019 Feb 14:1-16. Epub 2019 Feb 14.

b Grady College of Journalism and Mass Communication , University of Georgia.

An increasing lack of information truthfulness has become a fundamental challenge to communications. Insights into how to debunk this type of misinformation can especially be crucial for public health crises. To identify corrective information strategies that increase awareness and trigger actions during infectious disease outbreaks, an online experiment (N = 700) was conducted, using a U. Read More

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http://dx.doi.org/10.1080/10410236.2019.1573295DOI Listing
February 2019
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Point-Of-Care Testing Curriculum and Accreditation for Public Health-Enabling Preparedness, Response, and Higher Standards of Care at Points of Need.

Front Public Health 2018 29;6:385. Epub 2019 Jan 29.

Point-of-Care Testing Center for Teaching and Research, Pathology and Laboratory Medicine, School of Medicine, University of California, Davis, Davis, CA, United States.

To develop awareness of benefits of point-of-care testing (POCT) education in schools of public health, to identify learning objectives for teaching POCT, to enable public health professionals and emergency responders to perform evidence-based diagnosis and triage effectively and efficiently at points of need, and to better improve future standards of care for public health practice, including in limited-resource settings and crisis situations. We surveyed all U.S. Read More

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https://www.frontiersin.org/article/10.3389/fpubh.2018.00385
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http://dx.doi.org/10.3389/fpubh.2018.00385DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361824PMC
January 2019
3 Reads

Biosynthesized Highly Stable Au/C Nanodots: Ideal Probes for the Selective and Sensitive Detection of Hg Ions.

Nanomaterials (Basel) 2019 Feb 12;9(2). Epub 2019 Feb 12.

Department of Bionanotechnology, Gachon University, Gyeonggi-do 13120, Korea.

The enormous ongoing industrial development has caused serious water pollution which has become a major crisis, particularly in developing countries. Among the various water pollutants, non-biodegradable heavy metal ions are the most prevalent. Thus, trace-level detection of these metal ions using a simple technique is essential. Read More

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http://dx.doi.org/10.3390/nano9020245DOI Listing
February 2019

Characterization of 17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(indole-7-carboxamido)morphinan (NAN) as a Novel Opioid Receptor Modulator for Opioid Use Disorder Treatment.

ACS Chem Neurosci 2019 Feb 13. Epub 2019 Feb 13.

The opioid crisis is a significant public health issue with more than 115 people dying from opioid overdose per day in the US. The aim of the present study was to characterize the in vitro and in vivo pharmacological effects of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(indole-7-carboxamido)morphinan (NAN), a  opioid receptor (MOR) ligand that may be a potential candidate for opioid use disorder treatment that produces less withdrawal signs than naltrexone. The efficacy of NAN was compared to varying efficacy ligands at the MOR, and determined at the δ opioid receptor (DOR) and κ opioid receptor (KOR). Read More

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http://dx.doi.org/10.1021/acschemneuro.9b00038DOI Listing
February 2019
2 Reads

Haemoglobinopathies in India: estimates of blood requirements and treatment costs for the decade 2017-2026.

J Community Genet 2019 Feb 12. Epub 2019 Feb 12.

Centre for Comparative Genomics, Murdoch University, Perth, Australia.

The Government of India is presently engaged in the implementation of a prevention and control programme for two major forms of haemoglobinopathies, thalassaemia major and sickle cell disease, with guidelines for their prevention and management formulated under the National Health Mission. Based on projections for the population up to the year 2026, the annual blood requirement for treatment will increase to 9.24 million units, together with an 86% increase in budgetary requirements which then would account for over 19% of the current National Health Budget. Read More

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http://dx.doi.org/10.1007/s12687-019-00410-1DOI Listing
February 2019

Stroke Mimic Caused by Acetazolamide.

Eur J Case Rep Intern Med 2018 25;5(5):000822. Epub 2018 May 25.

Department of Medicine, Unidade Local de Saude do Alto Minho, Hospital Conde de Bertiandos, Ponte do Lima, Portugal.

Objectives: To describe a case of a stroke mimic caused by iatrogenic ataxia due to acetazolamide.

Case Description: An 86-year-old man with a history of gout and glaucoma, presented to the emergency department with progressive confusion, dizziness, disequilibrium and slurred speech, 3 days after he had started acetazolamide following ocular surgery. Physical examination showed he was hypertensive and had dysarthria; it was not possible to observe his gait due to pain in the right foot presumed to be due to a gout crisis. Read More

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http://dx.doi.org/10.12890/2018_000822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346928PMC

Delayed Diagnosis of Atypical Presentation of Myasthenia Gravis.

Eur J Case Rep Intern Med 2018 22;5(2):000785. Epub 2018 Feb 22.

Internal Medicine Department, St. Luke General Hospital, Kilkenny, Ireland.

Myasthenia gravis is an autoimmune disorder affecting the neuromuscular junction, resulting in muscle fatiguability and weakness. The pathological characteristics of the disorder include ocular weakness resulting in diplopia and/or ptosis. More generally, the disease can result in fluctuant weakness of skeletal muscle, predominantly affecting ocular, bulbar and respiratory muscles. Read More

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http://dx.doi.org/10.12890/2017_000785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346934PMC
February 2018
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Ectopic Parathyroid Adenoma: Surgical Correction and its Complication Management.

Mymensingh Med J 2019 Jan;28(1):245-249

Dr Mohammad Samir Azam Sunny, Medical Officer, Department of Cardiac Surgery, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh; E-mail:

Ectopic parathyroid are most frequently found in the anterior mediastinum, in association with the thymus or the thyroid gland. Ectopic parathyroid glands are a major cause of persistent and recurrent Hyperparathyroidism. We report a case of 65-year-old female was referred from Surgical Endocrine department to the department of Cardiac Surgery on 20 September, 2017 in Bangabandhu Sheikh Mujib Medical University with parathyroid crisis due to an ectopic mediastinal parathyroid adenoma with her serum calcium and PTH markedly increased in short time. Read More

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January 2019
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Nuclear disaster as chronic crisis: Accounts of radiation embodiment by survivors of the Chernobyl nuclear disaster from Belarus born before, in and after 1986.

Health (London) 2019 Feb 13:1363459319829190. Epub 2019 Feb 13.

Lund University, Sweden.

This article looks at chronic crisis on an empirical example of radiation embodiment by survivors of a nuclear disaster. Developing further the work of Henrik Vigh, this article argues that chronic crisis is conflictual in nature, where some individuals fully embrace it, while others reject it. A total of 16 in-depth interviews were conducted with survivors of the Chernobyl nuclear disaster from Belarus who were below 18 years in 1986 and born in or after 1986. Read More

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http://dx.doi.org/10.1177/1363459319829190DOI Listing
February 2019
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Slow crisis in the emergency department: bed block and human rights.

Authors:
Andrew Amos

Australas Psychiatry 2019 Feb;27(1):6-7

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http://dx.doi.org/10.1177/1039856218818316aDOI Listing
February 2019
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Social Norms Influencing the Local Food Environment as Perceived by Residents and Food Traders: The Heart Healthy Hoods Project.

Int J Environ Res Public Health 2019 Feb 11;16(3). Epub 2019 Feb 11.

Surgery and Medical and Social Sciences Department, School of Medicine, University of Alcalá, Alcalá de Henares, 28871 Madrid, Spain.

Exploring subjective elements of the food environment remains key to understand why and how residents purchase food. Our aim was to explore and describe the social norms relating to the local food environment and food purchasing behaviors, as perceived by residents and food traders in Madrid, Spain. This qualitative study took place in a middle socioeconomic status neighborhood of Madrid between January 2015 and May 2016. Read More

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http://dx.doi.org/10.3390/ijerph16030502DOI Listing
February 2019
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Safety of high-dose intravenous labetalol in hypertensive crisis.

Am J Health Syst Pharm 2019 Feb;76(5):286-292

Department of Surgery, St. Joseph Mercy Hospital, Ann Arbor, MI.

Purpose: The study assesses the safety of high-dose intravenous (i.v.) labetalol in adults. Read More

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http://dx.doi.org/10.1093/ajhp/zxy045DOI Listing
February 2019
2 Reads

Financial risk protection at the bedside: How Ethiopian physicians try to minimize out-of-pocket health expenditures.

PLoS One 2019 12;14(2):e0212129. Epub 2019 Feb 12.

Department of Bioethics, National Institutes of Health, Bethesda, Maryland, United States of America.

Background: Out-of-pocket health expenditures can pose major financial risks, create access-barriers and drive patients and families into poverty. Little is known about physicians' role in financial protection of patients and families at the bedside in low-income settings and how they perceive their roles and duties when treating patients in a health care system requiring high out-of-pocket costs.

Objective: Assess physicians' concerns regarding financial welfare of patients and their families and analyze physicians' experiences in reducing catastrophic health expenditures for patients in Ethiopia. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212129PLOS
February 2019
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Beliefs Associated with Pharmacy-Based Naloxone: a Qualitative Study of Pharmacy-Based Naloxone Purchasers and People at Risk for Opioid Overdose.

J Urban Health 2019 Feb 11. Epub 2019 Feb 11.

Departments of Emergency Medicine and Epidemiology, Alpert Medical School of Brown University, Providence, RI, USA.

Drug overdose is the leading cause of unintentional death in the USA and the majority of deaths involve an opioid. Pharmacies are playing an increasingly important role in getting naloxone-the antidote to an opioid overdose-into the community. The aim of the current study was to understand, from the perspective of those who had obtained naloxone at the pharmacy, whose drug using status and pain patient status was not known until the interviews were conducted, as well as those who had not obtained naloxone at the pharmacy but were at risk for overdose, factors that impact the likelihood of obtaining pharmacy-based naloxone (PBN). Read More

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http://dx.doi.org/10.1007/s11524-019-00349-1DOI Listing
February 2019
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The impact of the long-lasting socioeconomic crisis in Greece.

BJPsych Int 2019 Feb;16(1):16-18

Faculty of Social and Political Sciences, University of Peloponnese, Corinth, Greece.

Since 2009, Greece has experienced a long-lasting socioeconomic crisis that has had substantial consequences on the health and mental health of the population. Unemployment, financial hardship and income loss constitute the hallmarks of the socioeconomic landscape. Consequently, a substantial decline in health and mental health has been documented. Read More

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http://dx.doi.org/10.1192/bji.2017.31DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357520PMC
February 2019
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CIT in small municipalities: Officer-level outcomes.

Authors:
Carla G Strassle

Behav Sci Law 2019 Feb 12. Epub 2019 Feb 12.

Department of Psychology, School of Behavioral Sciences and Education, York College of Pennsylvania, York, PA, 17403, USA.

Research on the Crisis Intervention Team (CIT) as a method to deal with mental illness in policing encounters has primarily focused on officers from large urban areas. The current study examined officer-level outcomes in a non-urban geographical setting using a pre/post-CIT training design. The sample included 46 police officers from seven departments that would be considered rural and 13 that would be classified as suburban. Read More

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http://dx.doi.org/10.1002/bsl.2395DOI Listing
February 2019
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