Search our Database of Scientific Publications and Authors

I’m looking for a

    47906 results match your criteria Myxedema Coma or Crisis

    1 OF 959

    Philadelphia chromosome-positive acute myeloid leukemia with masses and osteolytic lesions: finding of 18F-FDG PET/CT.
    Front Med 2017 May 27. Epub 2017 May 27.
    Department of Haematology, Qilu Hospital, Shandong University, Jinan, 250012, China.
    Philadelphia chromosome-positive acute myeloid leukemia is controversial and difficult to distinguish from the blast phase of chronic myeloid leukemia. As a myeloid neoplasm, rare cases of this leukemia manifest multiple soft-tissue tumors or bone lytic lesions. In this paper, we describe a 49-year-old male patient who had an abrupt onset with sharp chest pain, fever, fatigue, emaciation, and splenomegaly. Read More

    Iodinated contrast agents in patients with myasthenia gravis: a retrospective cohort study.
    J Neurol 2017 May 26. Epub 2017 May 26.
    Department of Neurology, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
    Currently, it has not been satisfactorily established, whether modern low-osmolality iodinated contrast agents (ICAs) used in computed tomography (CT) studies are a risk factor for exacerbation of myasthenic symptoms. The rate of acute adverse events as well as delayed clinical worsening up to 30 days were analyzed in 73 patients with confirmed myasthenia gravis (MG) who underwent contrast-enhanced CT studies and compared to 52 patients who underwent unenhanced CT studies. One acute adverse event was documented. Read More

    Associations of physical fitness and body composition characteristics with simulated military task performance.
    J Strength Cond Res 2017 May 25. Epub 2017 May 25.
    1 Defence Command, Finnish Defence Forces, Helsinki, Finland 2 National Defence University, Helsinki, Finland 3 Department of Biology of Physical Activity, University of Jyväskylä, Jyväskylä, Finland.
    The purpose of the present study was to evaluate the associations of physical fitness and body composition characteristics with anaerobic endurance performance, tested in the combat load using the occupationally relevant military simulation test (MST). Eighty-one male soldiers, deployed to a crisis management operation in the Middle East, volunteered for the study and participated in a test battery consisting measurements of muscle strength, body composition characteristics, endurance capacity, and MST.A Spearman correlational analysis revealed that the strongest variable, correlated with MST time, was the countermovement jump performed with the combat load (CMJ2) (rs = -0. Read More

    Life-threatening posterior reversible encephalopathy syndrome in the cerebellum treated by posterior fossa decompression.
    Acta Neurochir (Wien) 2017 May 25. Epub 2017 May 25.
    Department of Neurosurgery, Heinrich Heine University Duesseldorf, Moorenstr. 5, 40225, Duesseldorf, Germany.
    Posterior reversible encephalopathy syndrome (PRES) is a clinico-neuroradiological syndrome associated with various clinical conditions, such as headache, encephalopathy, and seizures. It is reversible if a prompt diagnosis is made and treatment undertaken. We report a 52-year-old male with hypertensive crisis. Read More

    New developments in managing opioid addiction: impact of a subdermal buprenorphine implant.
    Drug Des Devel Ther 2017 10;11:1429-1437. Epub 2017 May 10.
    Department of Neurological Surgery, Johns Hopkins School of Medicine, Baltimore, MD, USA.
    Opioid addiction to prescription and illicit drugs is a serious and growing problem. In the US alone, >2.4 million people suffer from opioid use disorder. Read More

    Disruption of mitochondrial electron transport chain function potentiates the pro-apoptotic effects of MAPK inhibition.
    J Biol Chem 2017 May 25. Epub 2017 May 25.
    Icahn School of Medicine at Mount Sinai, United States;
    The mitochondrial network is a major site of ATP production through the coupled integration of the electron transport chain (ETC) with oxidative phosphorylation. In melanoma, arising from the Val600Glu mutation in the kinase v-RAF murine sarcoma viral oncogene homolog B (BRAFV600E), oncogenic signaling enhances glucose-dependent metabolism, while reducing mitochondrial ATP production. Likewise, when BRAFV600E is pharmacologically inhibited by targeted therapies (e. Read More

    Hydrocarbon Assessment and Prediction due to the Gulf War Oil Disaster, North Kuwait.
    Water Environ Res 2017 Jun;89(6):484-499
      Oil spill in the Gulf was the biggest disaster in history. The scale of damage was enormous, ranging from destruction caused by oil fires and oil spills, to economic decline for the Kuwaiti oil industry. The transport modelling of the freshwater aquifers in north Kuwait was undertaken to assess potential remediation scenarios using the MODFLOW-SURFACT numerical code. Read More

    Family functioning and perceived support from nurses during cancer treatment among Danish and Australian patients and their families.
    J Clin Nurs 2017 May 25. Epub 2017 May 25.
    University of Southern Denmark, Department of Clinical Research, Campusvej 55, 5000, Odense C, Denmark.
    Aims And Objectives: This study aims to compare family functioning and perceptions of support from nurses among Danish and Australian adult oncology patients and family members.

    Background: Family can have a strong influence on the health of individuals, providing support during a health crisis such as cancer. However, family functioning and supportive care from nurses may vary across cultures and settings. Read More

    Crisis at Guy's Hospital (1880) and the nature of nursing work.
    Nurs Inq 2017 May 23. Epub 2017 May 23.
    The School of Nursing, Midwifery and Social Work, The University of Manchester, Manchester, UK.
    This historical study aims to refine understanding of the nature of nursing work. The study focuses on the 1880 crisis at Guy's Hospital in London to examine the nature and meaning of nursing work, particularly the concept of nursing work as many 'little things.' In this paper, an examination of Margaret Lonsdale's writing offers an original contribution to our understanding of the ways in which nursing work differs from medical practice. Read More

    Opioid Treatment Agreements Repurposed-But Who Monitors the Monitors?
    Hastings Cent Rep 2017 May;47(3):36-37
    In this issue of the Hastings Center Report, Joshua Rager and Peter Schwartz reframe the justification for the use of opioid treatment agreements. Instead of documents used to define the roles and responsibilities of doctors and patients to one another in the course of opioid treatment for chronic pain and to describe the risks and benefits of therapy for the individual, OTAs are now proposed for use as "surveillance and monitoring" instruments. As such, they are specifically meant to disclose the risks of opioid therapy and to describe the other processes and tools used to monitor abuse and diversion of medications. Read More

    Environmental constraints on the compositional and phylogenetic beta-diversity of tropical forest snake assemblages.
    J Anim Ecol 2017 May 22. Epub 2017 May 22.
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, USA.
    The ongoing biodiversity crisis increases the importance and urgency of studies addressing the role of environmental variation on the composition and evolutionary history of species assemblages, but especially the tropics and ectotherms remain understudied. In regions with rainy summers, coexistence of ectothermic species may be determined by the partitioning of the climatic niche, since ectotherms can rely on water availability and thermoregulatory behaviour to buffer constraints along their climatic niche. Conversely, ectotherms facing dry summers would have fewer opportunities to climatic niche partitioning and other processes rather than environmental filtering would mediate species coexistence. Read More

    Biophysical markers of the peripheral vasoconstriction response to pain in sickle cell disease.
    PLoS One 2017 24;12(5):e0178353. Epub 2017 May 24.
    Department of Biomedical Engineering, University of Southern California, Los Angeles, California, United States of America.
    Painful vaso-occlusive crisis (VOC), a complication of sickle cell disease (SCD), occurs when sickled red blood cells obstruct flow in the microvasculature. We postulated that exaggerated sympathetically mediated vasoconstriction, endothelial dysfunction and the synergistic interaction between these two factors act together to reduce microvascular flow, promoting regional vaso-occlusions, setting the stage for VOC. We previously found that SCD subjects had stronger vasoconstriction response to pulses of heat-induced pain compared to controls but the relative degrees to which autonomic dysregulation, peripheral vascular dysfunction and their interaction are present in SCD remain unknown. Read More

    A window-DEA based efficiency evaluation of the public hospital sector in Greece during the 5-year economic crisis.
    PLoS One 2017 23;12(5):e0177946. Epub 2017 May 23.
    School of Social Sciences, Hellenic Open University, Patra, Greece.
    The main objective of this study was to apply the non-parametric method of Data Envelopment Analysis (DEA) to measure the efficiency of Greek NHS hospitals between 2009-2013. Hospitals were divided into four separate groups with common characteristics which allowed comparisons to be carried out in the context of increased homogeneity. The window-DEA method was chosen since it leads to increased discrimination on the results especially when applied to small samples and it enables year-by-year comparisons of the results. Read More

    The Technology Crisis in Neuropsychology.
    Arch Clin Neuropsychol 2017 May 24:1-14. Epub 2017 May 24.
    NYU, School of Medicine, New York, NY, USA.
    Neuropsychology has fallen reliant on outdated and labor intensive methods of data collection that are slow, highly inefficient, and expensive, and provide relatively data-poor estimates of human behavior despite rapid technological advance in most other fields of medicine. Here we present a brief historical overview of current testing practices in an effort to frame the current crisis, followed by an overview of different settings in which technology can and should be integrated. Potential benefits of laboratory based assessments, remote assessments, as well as passive and high-frequency data collection tools rooted in technology are discussed, along with several relevant examples and how these technologies might be deployed. Read More

    Psychiatric specialty training in Greece.
    Psychiatriki 2017 Jan-Mar;28(1):15-18
    Em. Professor of Psychiatry, University of Athens.
    The reform and development of psychiatric services require, in addition to financial resources, reserves in specialized human resources. The role of psychiatrists in this process, and at reducing the consequences of mental morbidity is evident. Psychiatrists are required to play a multifaceted role as clinicians, as experts in multidisciplinary team environments and as advisors in the recognition of public needs in mental health issues, as teachers and mentors for students and other health professionals, as researchers in order to enrich our knowledge in the scientific field of psychiatry, and as public health specialists in the development of the mental health services system. Read More

    Factors Associated with Emotional Distress in Children and Adolescents during Early Treatment for Cancer.
    Yonsei Med J 2017 Jul;58(4):816-822
    Division of Child and Adolescent Psychiatry, Department of Psychiatry, Yonsei University College of Medicine, Yonsei University Health System, Seoul, Korea.
    Purpose: Children and adolescents diagnosed with cancer experience emotional distress, such as sadness, worrying, and irritability. However, there is little information about the psychological well-being of parents at the time of their child's diagnosis. We sought to identify factors that were associated with emotional distress in cancer patients as a basis for developing innovative psychological interventions. Read More

    Hemoglobin and mean platelet volume predicts diffuse T1-MRI white matter volume decrease in sickle cell disease patients.
    Neuroimage Clin 2017 29;15:239-246. Epub 2017 Apr 29.
    Department of Pediatrics and Radiology, Children's Hospital Los Angeles USC, 4650 Sunset Blvd., MS #81, Los Angeles, CA 90027, USA.
    Sickle cell disease (SCD) is a life-threatening genetic condition. Patients suffer from chronic systemic and cerebral vascular disease that leads to early and cumulative neurological damage. Few studies have quantified the effects of this disease on brain morphometry and even fewer efforts have been devoted to older patients despite the progressive nature of the disease. Read More

    Myxedema Crisis Presenting with Seizures: A Rare Life-Threatening Presentation-A Case Report and Review of the Literature.
    Case Rep Endocrinol 2017 2;2017:4285457. Epub 2017 May 2.
    Endocrinology, Colombo South Teaching Hospital, Kalubowila, Sri Lanka.
    Myxedema crisis is a life-threatening extreme form of hypothyroidism with a high mortality rate if left untreated. Myxedema crisis is commonly seen in older patients, especially in women, and is associated with signs of hypothyroidism, hypothermia, hyponatraemia, hypercarbia, and hypoxemia. Patients might present with different organ specific symptoms. Read More

    Anti-MuSK-Positive Myasthenic Crisis in a 7-Year-Old Female.
    Case Rep Emerg Med 2017 30;2017:8762302. Epub 2017 Apr 30.
    Department of Emergency Medicine, UF Health Shands Hospital, Gainesville, FL, USA.
    A seven-year-old African American female with anti-MuSK-positive Juvenile Myasthenia Gravis collapsed while at school from progressively worsening weakness and dyspnea. On initial emergency department presentation, she required 15 liters per minute of supplemental oxygen to maintain oxygen saturation above 92%. Initial pulmonary function tests and venous blood gas led to the decision to place her on noninvasive positive pressure ventilation (NPPV) with BiPAP in the emergency department. Read More

    Assocation of a Surgical Task During Training With Team Skill Acquisition Among Surgical Residents: The Missing Piece in Multidisciplinary Team Training.
    JAMA Surg 2017 May 24. Epub 2017 May 24.
    Wake Forest Baptist Health, Winston Salem, North Carolina.
    Importance: The human patient simulators that are currently used in multidisciplinary operating room team training scenarios cannot simulate surgical tasks because they lack a realistic surgical anatomy. Thus, they eliminate the surgeon's primary task in the operating room. The surgical trainee is presented with a significant barrier when he or she attempts to suspend disbelief and engage in the scenario. Read More

    Impact of a Novel PI3-KINASE Inhibitor in Preventing Mitochondrial DNA Damage and Damage Associated Molecular Pattern Accumulation: Results from the Biochronicity Project.
    J Trauma Acute Care Surg 2017 May 22. Epub 2017 May 22.
    1Dept. of Surgery, Madigan Army Medical Center, Joint Base Lewis-McChord, Washington 2Dept. of Surgery, University of South Alabama, Mobile, Alabama 3Dept. of Pharmacology, University of South Alabama, Mobile, Alabama 4Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 5Trauma and Acute Care Surgery Service, Legacy Emanuel Medical Center, Portland, Oregon.
    Background: Despite improvements in the management of severely injured patients, development of multiple organ dysfunction syndrome (MODS) remains a morbid complication of traumatic shock. One of the key attributes of MODS is a profound bioenergetics crisis, for which the mediators and mechanisms are poorly understood. We hypothesized that metabolic uncoupling using an experimental PI3-kinase inhibitor, LY294002 (LY), may prevent mitochondrial abnormalities that lead to the generation of mitochondrial DNA (mtDNA) damage and the release of mtDNA damage associated molecular patterns (DAMPs) METHODS: 16 swine were studied using LY294002 (LY), a non-selective PI3-KI: Animals were assigned to Trauma only (TO, N=3); LY drug only (LYO, N=3); and Experimental (N=10), trauma + drug (LY+T) groups. Read More

    The HEADS-ED: Evaluating the Clinical Use of a Brief, Action-Oriented, Pediatric Mental Health Screening Tool.
    Pediatr Emerg Care 2017 May 23. Epub 2017 May 23.
    From the *Mental Health Patient Service Unit, Children's Hospital of Eastern Ontario; Departments of †Psychiatry and ‡Psychology, University of Ottawa; §Emergency Department, Children's Hospital of Eastern Ontario; ∥Clinical Research Unit, Children's Hospital of Eastern Ontario Research Institute; ¶Department of Pediatrics, University of Ottawa; **Mental Health Research, Children's Hospital of Eastern Ontario; and ††Department of Psychology, Carleton University, Ottawa, Canada.
    Objectives: This effectiveness study aimed to evaluate the clinical use of the HEADS-ED tool for patients presenting to a pediatric emergency department (PED) for mental health (MH) care.

    Methods: In this pragmatic trial, PED physicians used the HEADS-ED to guide their assessment and identify areas of MH need in 639 patients (mean [SD], 15.16 [1. Read More

    A case report of pedigree of a homozygous mutation of the steroidogenic acute regulatory protein causing lipoid congenital adrenal hyperplasia.
    Medicine (Baltimore) 2017 May;96(21):e6994
    aDepartment of Endocrinology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Key Laboratory of Health and Family Planning Commission, Beijing, China bThe Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China.
    Rationale: Lipoid congenital adrenal hyperplasia (LCAH) is extremely rare, but is the most fatal form of congenital adrenal hyperplasia resulting from mutations in the steroidogenic acute regulatory protein (STAR) gene. LCAH arises from severe defects in the conversion of cholesterol to pregnenolone, the precursor of all steroids.

    Patient Concerns: A case was reported that an 11-month-old Chinese girl who presented with a sex development disorder and hyponatremia. Read More

    Myxedema coma: A case report of pediatric emergency care.
    Medicine (Baltimore) 2017 May;96(21):e6952
    aPediatric Critical Care Medicine, Xinhua Hospital affiliated to Shanghai Jiaotong University School of Medicine bDepartment of Pediatric Endocrinology/Genetics, Xinhua Hospital affiliated to Shanghai Jiaotong University School of Medicine, Shanghai Institute for Pediatric Research, Shanghai, China.
    Raionale: Myxedema coma (MC) is extremely rare but lethal in pediatric patients with hypothyroidism leading to altered mental status and hypothermia. But there is no clinical guideline for such cases.

    Patient Concerns: A 6-year-old Chinese girl presented with coma and hypothermia preceded by pneumonia. Read More

    Providing Coordinated Cancer Care-A Qualitative Study of Norwegian Cancer Coordinators' Experiences of Their Role.
    Cancer Nurs 2017 May 23. Epub 2017 May 23.
    Author Affiliations: Department of Physiotherapy, Faculty of Health Sciences, Oslo and Akershus University College of Applied Sciences (Ms Lie and Dr Solvang); and Center for Crisis Psychology, Bergen (Dr Hauken), Norway.
    Background: There is a growing need for strategies to improve coordinated, tailored services in cancer care to meet the comprehensive needs of cancer patients. In Norway, cancer coordinators (CCs) have been established to improve coordination and patient-centeredness of services. Little is known about how CCs engage to provide patients with the needed services and support throughout the treatment. Read More

    High Rates of Access to Health Care, Disclosure of Sexuality and Gender Identity to Providers among House and Ball Community Members in New York City.
    J Homosex 2017 May 24. Epub 2017 May 24.
    d Gay Men's Health Crisis (GMHC) , New York , New York , USA.
    The House and Ball community is an important cultural manifestation of resiliency for Black and Latino gay and bisexual men and transgender women. Participants at the August, 2013 House of Latex Ball in New York City were surveyed about insurance coverage, health care access, experiences in health care, and housing instability. The sample (n = 367) was 58% Black/African American and 20% Hispanic/Latino, with a mean age of 31. Read More

    "Invisible during My Own Crisis": Responses of LGBT People of Color to the Orlando Shooting.
    J Homosex 2017 May 24. Epub 2017 May 24.
    a Department of Psychology , Towson University , Towson , Maryland , USA.
    On June 12th, 2016, the Pulse nightclub in Orlando, Florida was the target of one of the country's deadliest mass shootings. Pulse, a gay nightclub, was hosting a Latin Pride Night the evening of the tragedy, resulting in the death of 49 victims and 53 casualties, over 90% of whom were lesbian, gay, bisexual, and transgender (LGBT) Latinx people, specifically. The present research investigates the narrative responses from LGBT people of color (LGBT-POC) following the tragedy. Read More

    [Evolution of Asthma Prevalence and Sociodemographic and Health Factors Associated in Madrid Region (1996-2013)].
    Rev Esp Salud Publica 2017 05 25;91. Epub 2017 May 25.
    Servicio de Epidemiología. Dirección General de Salud Pública. Madrid. España.
    Objective: Asthma is an important public health issue. The goal of this study is to analyse the trends in self-reported asthma prevalence in the Madrid Region and its association with socio-demographic and health factors.

    Methods: Data from the "Non-Communicable Disease Risk Factor Surveillance System" in adult population (SIVFRENT-A) 1996-2013 were used. Read More

    Economic conditions, hypertension, and cardiovascular disease: analysis of the Icelandic economic collapse.
    Health Econ Rev 2017 Dec 23;7(1):20. Epub 2017 May 23.
    Faculty of Economics, University of Iceland, Oddi v/Sturlugotu, 101, Reykjavik, Iceland.
    Previous research has found a positive short-term relationship between the 2008 collapse and hypertension in Icelandic males. With Iceland's economy experiencing a phase of economic recovery, an opportunity to pursue a longer-term analysis of the collapse has emerged. Using data from a nationally representative sample, fixed-effect estimations and mediation analyses were performed to explore the relationship between the Icelandic economic collapse in 2008 and the longer-term impact on hypertension and cardiovascular health. Read More

    Pediatric Firearm-Related Injuries in the United States.
    Hosp Pediatr 2017 May 23. Epub 2017 May 23.
    Division of Emergency Medicine, Children's National Health System, Washington, DC.
    Pediatric firearm-related deaths and injuries are a national public health crisis. In this Special Review Article, we characterize the epidemiology of firearm-related injuries in the United States and discuss public health programs, the role of pediatricians, and legislative efforts to address this health crisis. Firearm-related injuries are leading causes of unintentional injury deaths in children and adolescents. Read More

    The effectiveness of telemedicine-delivered opioid agonist therapy in a supervised clinical setting.
    Drug Alcohol Depend 2017 May 17;176:133-138. Epub 2017 May 17.
    Northern Ontario School of Medicine, 935 Ramsey Lake Rd., Sudbury, ON, P3E 2C6, Canada; Canadian Addiction Treatment Centers, 13291 Yonge St., Ste. 403, Richmond Hill, ON L4E 4L6, Canada. Electronic address:
    Objective: Opioid use disorder has been declared a public health crisis across North America and opioid agonist therapy (OAT) is the standard of care for these patients. Despite the increasing adoption of telemedicine as a delivery method for OAT, its effectiveness has not yet been evaluated against traditional in-person treatment. This study compared treatment outcomes for in-person versus telemedicine-delivered OAT. Read More

    Prevalence and costs of defensive medicine: a national survey of Italian physicians.
    J Health Serv Res Policy 2017 Jan 1:1355819617707224. Epub 2017 Jan 1.
    5 Professor, Biomedical Sciences and Public Health, Universita' Politecnica delle Marche, Ancona, Italy.
    Objective To identify the prevalence of the practice of defensive medicine among Italian hospital physicians, its costs and the reasons for practising defensive medicine and possible solutions to reduce the practice of defensive medicine. Methods Cross-sectional web survey. Main outcome measures Number of physicians reporting having engaged in any defensive medicine behaviour in the previous year. Read More

    An American Crisis: the Lack of Black Men in Medicine.
    J Racial Ethn Health Disparities 2017 Jun 22;4(3):317-321. Epub 2017 May 22.
    School of Medicine, University of Connecticut Health Center, Farmington, CT, USA.
    The current state of diversity within the US medical workforce does not reflect representative numbers of the Black male population. Research data continues to reveal continuing trends in the areas of discrimination, incarceration, health disparities, and mortality with respect to Black males. The lack of increase in Black male medical school applications and matriculation contrasted by the continuing trends mentioned above illustrates that there is in fact an American crisis. Read More

    Readability comparison of pro- and anti-HPV-vaccination online messages in Japan.
    Patient Educ Couns 2017 May 13. Epub 2017 May 13.
    Department of Health Communication, School of Public Health, The University of Tokyo, Tokyo, Japan. Electronic address:
    Objective: In Japan, the HPV vaccination rate has sharply fallen to nearly 0% due to a series of sensational media reports of adverse events. Online anti-HPV-vaccination activists often warn readers of the vaccine's dangers. We aimed to examine distribution and readability of pro-and anti-vaccination online messages with relation to these authors' professional expertise. Read More

    Mitigating the heroin crisis in Baltimore, MD, USA: a cost-benefit analysis of a hypothetical supervised injection facility.
    Harm Reduct J 2017 May 12;14(1):29. Epub 2017 May 12.
    Criminal Justice Policy Foundation, Amherst College, Silver Spring, MD, USA.
    Background: In Baltimore, MD, as in many cities throughout the USA, overdose rates are on the rise due to both the increase of prescription opioid abuse and that of fentanyl and other synthetic opioids in the drug market. Supervised injection facilities (SIFs) are a widely implemented public health intervention throughout the world, with 97 existing in 11 countries worldwide. Research has documented the public health, social, and economic benefits of SIFs, yet none exist in the USA. Read More

    How geostatistics can help you find lead and galvanized water service lines: The case of Flint, MI.
    Sci Total Environ 2017 May 17;599-600:1552-1563. Epub 2017 May 17.
    BioMedware, Inc., PO Box 1577, Ann Arbor, MI 48106, USA. Electronic address:
    In the aftermath of Flint drinking water crisis, most US cities have been scrambling to locate all lead service lines (LSLs) in their water supply systems. This information, which is most often inaccurate or lacking, is critical to assess compliance with the Lead and Copper Rule and to plan the replacement of lead and galvanized service lines (GSLs) as currently under way in Flint. This paper presents the first geospatial approach to predict the likelihood that a home has a LSL or GSL based on neighboring field data (i. Read More

    Governmental efforts for cardiovascular disease prevention efforts in the Russian Federation.
    Cardiovasc Diagn Ther 2017 Apr;7(Suppl 1):S48-S54
    National Research Center for Preventive Medicine, Moscow, Russia.
    Cardiovascular disease (CVD) is the leading cause of death and disability in Russia as is case with the most other countries of the world, although Russia has unique features and demographic trends. In the late 90's and early 2000's Russia has sustained a profound demographical crisis with a period of overmortality but since 2003 the mortality rates are declining. By 2013, the birth rates exceeded mortality. Read More

    Responding to a cVDPV1 outbreak in Ukraine: Implications, challenges and opportunities.
    Vaccine 2017 May 18. Epub 2017 May 18.
    World Health Organization Regional Office for Europe, Copenhagen, Denmark.
    Background: The European Region, certified polio-free in 2002, remains at risk of wild poliovirus reintroduction and emergence of circulating vaccine-derived polioviruses (cVDPV) until global polio eradication is achieved, as demonstrated by the cVDPV1 outbreak in Ukraine in 2015.

    Methods: We reviewed epidemiologic, clinical and virology data on cVDPV cases, surveillance and immunization coverage data, and reports of outbreak-related surveys, country missions, and expert group meetings.

    Results: In Ukraine, 3-dose polio vaccine coverage declined from 91% in 2008 to 15% by mid-2015. Read More

    Using Lean to Rapidly and Sustainably Transform a Behavioral Health Crisis Program: Impact on Throughput and Safety.
    Jt Comm J Qual Patient Saf 2017 Jun 18;43(6):275-283. Epub 2017 Apr 18.
    Background: Lean has been increasingly applied in health care to reduce waste and improve quality, particularly in fast-paced and high-acuity clinical settings such as emergency departments. In addition, Lean's focus on engagement of frontline staff in problem solving can be a catalyst for organizational change. In this study, ConnectionsAZ demonstrates how they applied Lean principles to rapidly and sustainably transform clinical operations in a behavioral health crisis facility. Read More

    Isometric Handgrip as an Adjunct for Blood Pressure Control: a Primer for Clinicians.
    Curr Hypertens Rep 2017 Jun;19(6):51
    School of Medicine, Department of Emergency Medicine, Wayne State University, Detroit, MI, USA.
    Considered a global health crisis by the World Health Organization, hypertension (HTN) is the leading risk factor for death and disability. The majority of treated patients do not attain evidence-based clinical targets, which increases the risk of potentially fatal complications. HTN is the most common chronic condition seen in primary care; thus, implementing therapies that lower and maintain BP to within-target ranges is of tremendous public health importance. Read More

    Three-Quarters Adrenalectomy for Infantile-Onset Cushing Syndrome due to Bilateral Adrenal Hyperplasia in McCune-Albright Syndrome.
    Horm Res Paediatr 2017 May 19. Epub 2017 May 19.
    Department of Pediatrics, Oita University Faculty of Medicine, Oita, Japan.
    Background: Bilateral adrenalectomy is performed in cases with infantile-onset Cushing syndrome due to bilateral adrenal hyperplasia in McCune-Albright syndrome (MAS) because severe Cushing syndrome with heart failure and liver dysfunction can have a lethal outcome. This procedure can completely ameliorate hypercortisolism, although lifetime steroid replacement therapy and steps to prevent adrenal crisis are necessary. Recently, the efficacy of unilateral adrenalectomy has been reported in adult cases of bilateral macronodular adrenal hyperplasia, but there is no consensus regarding the appropriate surgical treatment for bilateral adrenal hyperplasia in MAS. Read More

    Parental Knowledge and Recall of Concussion Discharge Instructions.
    J Emerg Nurs 2017 May 17. Epub 2017 May 17.
    Milwaukee, WI.
    Introduction: Children increasingly are being seen in the emergency department for a concussion, or mild traumatic brain injury (mTBI). A key aim of the ED visit is to provide discharge advice that can help parents to identify an evolving neurosurgical crisis, facilitate recovery, and prevent reinjury. The present study examined parents' knowledge of symptoms and recall of discharge instructions after their adolescent's mTBI and the effect of supplementing written discharge instructions with verbal instruction and reinforcement. Read More

    1 OF 959