69,544 results match your criteria Myxedema Coma or Crisis


How lockdown measures, during COVID-19 pandemic, matter on psoriatic patient's perception: Study on 600 patients on biologic therapy.

J Infect Public Health 2021 Apr 1;14(7):878-882. Epub 2021 Apr 1.

Dermatology Unit "D. Innocenzi", Polo Pontino, Sapienza University of Rome, Rome, Italy.

Background: The outbreak of coronavirus disease-2019 (COVID-19) is a public health crisis of global proportion. In psoriatic patients treated with biologic agents, evidence is not yet available on susceptibility to infection with the novel SARS-CoV-2 coronavirus, and data about the perception of COVID-19 and its impact on these patients are lacking.

Aims: The aim of this observational, spontaneous study was the evaluation of the impact of anti COVID-19 measures in "fragile population" such as patients with a chronic inflammatory disease. Read More

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New perspective towards therapeutic regimen against SARS-CoV-2 infection.

J Infect Public Health 2021 May 26;14(7):852-862. Epub 2021 May 26.

Clinical Microbiology and Infectious Diseases, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, 2193, South Africa; Infection Control, Charlotte Maxeke Johannesburg Academic Hospital, National Health Laboratory Service, Johannesburg, 2193, South Africa. Electronic address:

The ongoing enormous loss of human life owing to Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), has led to a global crisis ranging from the collapse of health - care systems to socio-economic instability. As SARS-CoV-2 is a novel virus, very little information is available from researchers and therefore, a rigorous effort is required to decode its pathogenicity. There are no licenced treatment options available for treating SARS-CoV-2 infections and the development of a new antiviral drug targeting coronavirus cannot happen soon. Read More

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Examining factors that shape use and access to diverted prescription opioids during an overdose crisis: A qualitative study in Vancouver, Canada.

J Subst Abuse Treat 2021 Apr 20;130:108418. Epub 2021 Apr 20.

Department of Medicine, University of British Columbia, St. Paul's Hospital, 608-1081 Burrard Street, Vancouver V6Z 1Y6, BC, Canada; British Columbia Centre on Substance Use, 400-1045 Howe Street, Vancouver V6Z 2A9, BC, Canada.

Objective: Prescription opioid (PO) diversion is widely regarded as a driver of overdose mortality. However, less is known about the rationale for using diverted POs during an overdose epidemic and how contextual factors (e.g. Read More

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Abiotic-biotic hybrid for CO biomethanation: From electrochemical to photochemical process.

Sci Total Environ 2021 Jun 5;791:148288. Epub 2021 Jun 5.

Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY 12180, USA.

Converting CO into sustainable fuels (e.g., CH) has great significance to solve carbon emission and energy crisis. Read More

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Pesticides are the dominant stressors for vulnerable insects in lowland streams.

Water Res 2021 May 17;201:117262. Epub 2021 May 17.

Department of River Ecology, Helmholtz Centre for Environmental Research, UFZ, 04318 Leipzig, Germany.

Despite elaborate regulation of agricultural pesticides, their occurrence in non-target areas has been linked to adverse ecological effects on insects in several field investigations. Their quantitative role in contributing to the biodiversity crisis is, however, still not known. In a large-scale study across 101 sites of small lowland streams in Central Europe, Germany we revealed that 83% of agricultural streams did not meet the pesticide-related ecological targets. Read More

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Rational construction of Ni(OH) nanoparticles on covalent triazine-based framework for artificial CO reduction.

J Colloid Interface Sci 2021 May 25;602:23-31. Epub 2021 May 25.

State Key Laboratory of Photocatalysis on Energy and Environment, Fuzhou University, 2 Xue Yuan Road, New Campus, Minhou, Fujian 350108, PR China.

Artificial photoreduction of CO to chemical fuel is an intriguing and reliable strategy to tackle the issues of energy crisis and climate change simultaneously. In the present study, we rationally constructed a Ni(OH)-modified covalent triazine-based framework (CTF-1) composites to serve as cocatalyst ensemble for superior photoreduction of CO. In particular, the optimal Ni(OH)-CTF-1 composites (loading ratio at 0. Read More

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Engineering of single-domain antibodies for next generation snakebite antivenoms.

Int J Biol Macromol 2021 Jun 9. Epub 2021 Jun 9.

Plataforma Bi-Institucional de Medicina Translacional (Fiocruz-USP), Ribeirão Preto, São Paulo, Brazil.

Given the magnitude of the global snakebite crisis, strategies to ensure the quality of antivenom, as well as the availability and sustainability of its supply are under development by several research groups. Recombinant DNA technology has allowed the engineering of monoclonal antibodies and recombinant fragments as alternatives to conventional antivenoms. Besides higher therapeutic efficacy, with broad neutralization capacity against local and systemic toxicity, novel antivenoms have to ensure safety and cost-effectivity. Read More

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Pushing the boundaries of prediction to address the opioid crisis.

Authors:
Evan M Lowder

Lancet Public Health 2021 Jun 9. Epub 2021 Jun 9.

Department of Criminology, Law, and Society, George Mason University, Fairfax, VA 22030, USA. Electronic address:

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The Saudi Ministry of Health Twitter Communication Strategies and Public Engagement, During the COVID-19 Pandemic: A Content Analysis Study.

JMIR Public Health Surveill 2021 Jun 11. Epub 2021 Jun 11.

College of Public Health and Health Informatics, King Saud bin Abdulaziz University for Health Sciences, Prince Mutib Ibn Abdullah Ibn Abdulaziz Rd, Ar Rimayah, Riyadh 14611, Riyadh, SA.

Background: During a public health crisis such as the current coronavirus pandemic, governments and health authorities need quick and accurate methods of communicating with the public. While social media can serve as a useful tool for effective communication during disease outbreaks, little research exists with regard to understanding how these platforms are used by the Ministry of Health (MOH) during outbreaks in Saudi Arabia.

Objective: Guided by the Crisis and Emergency Risk Communication (CERC) model, this study aimed to explore the MOH's use of Twitter and the public's engagement during different stages of the COVID-19 pandemic in Saudi Arabia. Read More

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Photoelectrochemical Water-Splitting Using CuO-Based Electrodes for Hydrogen Production: A Review.

Adv Mater 2021 Jun 12:e2007285. Epub 2021 Jun 12.

Institute for Photovoltaics, University of Stuttgart, Pfaffenwaldring 47, D-70569, Stuttgart, Germany.

The cost-effective, robust, and efficient electrocatalysts for photoelectrochemical (PEC) water-splitting has been extensively studied over the past decade to address a solution for the energy crisis. The interesting physicochemical properties of CuO have introduced this promising photocathodic material among the few photocatalysts with a narrow bandgap. This photocatalyst has a high activity for the PEC hydrogen evolution reaction (HER) under simulated sunlight irradiation. Read More

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Predoctoral substance use disorders curricula: A survey analysis and experiential pedagogy.

J Dent Educ 2021 Jun 11. Epub 2021 Jun 11.

New York State Psychiatric Institute, Columbia University, New York, New York.

Substance Use Disorders (SUD) are chronic health conditions with heritability characteristics, environmental influences, long-term management considerations and they cooccur. The US opioid epidemic is a crisis of both prescription and nonprescription opioid use. Clinicians now have access to evidence-based practices but the evolving trends require continuous attention including curriculum initiatives for dental schools. Read More

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COM crisis.

Br Dent J 2021 Jun;230(11):688-689

By email, Cardiff, UK.

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A 59-Year-Old Woman with Extensive Deep Vein Thrombosis and Pulmonary Thromboembolism 7 Days Following a First Dose of the Pfizer-BioNTech BNT162b2 mRNA COVID-19 Vaccine.

Am J Case Rep 2021 Jun 12;22:e932946. Epub 2021 Jun 12.

Department of Medicine, Sultan Qaboos University Hospital, Muscat, Oman.

BACKGROUND The COVID-19 pandemic is an ongoing cause of the current global healthcare crisis. Several vaccines were approved for use by emergency vaccination campaigns worldwide. At present, there are very few reports of COVID-19 vaccine-induced immune-thrombotic thrombocytopenia, a variant of heparin-induced thrombocytopenia (HIT), in comparison to the massive number of vaccinated people worldwide. Read More

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Use of Rapid Assessment Procedures when analyzing qualitative data in pharmacy research.

Res Social Adm Pharm 2021 Jun 6. Epub 2021 Jun 6.

Department of Clinical Pharmacy and Translational Science, University of Tennessee Health Science Center, College of Pharmacy, Nashville, TN, USA. Electronic address:

Qualitative research analytics and methodology are a useful part of many research projects. However, qualitative data analysis may be time intensive causing delays in results. This is especially problematic in time-sensitive projects where there an urgent need for results and a rapidly evolving situation being studied, such as during health crisis or early stages of project implementation. Read More

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A cross-sectional survey on community pharmacists readiness to fight COVID-19 in a developing country: knowledge, attitude, and practice in Lebanon.

J Pharm Policy Pract 2021 Jun 11;14(1):51. Epub 2021 Jun 11.

INSPECT-LB: Institut National de Santé Publique, d'Épidémiologie Clinique et de Toxicologie, Beirut, Lebanon.

Background: Lebanon, a developing Middle Eastern country, was hit by the COVID-19 pandemic that occurred amid a severe national economic crisis. Community pharmacists are responsible for dispensing appropriate medications and products in addition to counseling, informing and educating the public, and promoting disease prevention and infection control.

Objective: This study aimed to assess community pharmacists' knowledge, attitude, and practice towards the COVID-19 pandemic and evaluate behavior changes and safety measures. Read More

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Should nutritional therapy be modified to account for mitochondrial dysfunction in critical illness?

JPEN J Parenter Enteral Nutr 2021 Jun 11. Epub 2021 Jun 11.

William Harvey Research Institute, Queen Mary University of London, London.

Metabolic dysfunction, and its associated muscle atrophy, remains the most common complication of critical care. At the centre of this is mitochondrial dysfunction, secondary to hypoxia and systemic inflammation. This leads to a bioenergetic crisis, with decreased intramuscular adenosine tri-phosphate content and a reduction in the highly energy dependent process of protein synthesis. Read More

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The health response to the Rohingya refugee crisis post August 2017: Reflections from two years of health sector coordination in Cox's Bazar, Bangladesh.

PLoS One 2021 11;16(6):e0253013. Epub 2021 Jun 11.

Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom.

On August 25 2017, an unprecedented influx of Rohingya refugees began from Rakhine State in Myanmar into Bangladesh's district of Cox's Bazar. The scale and acuteness of this humanitarian crisis was unprecedented and unique globally, requiring strong coordination of a multitude of actors. This paper reflects on the health sector coordination from August 2017 to October 2019, focusing on selected achievements and persisting challenges of the health sector strategic advisory group (HSSAG), and the health sector working groups including epidemiology and case management, sexual and reproductive health, community health, mental health and psychosocial support, and emergency preparedness. Read More

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Validation of a Crisis Standards of Care Model for Prioritization of Limited Resources During the Coronavirus Disease 2019 Crisis in an Urban, Safety-Net, Academic Medical Center.

Crit Care Med 2021 Jun 9. Epub 2021 Jun 9.

Department of Medicine, Section of General Internal Medicine, Boston Medical Center, Boston, MA. Boston University School of Medicine, Boston, MA. Boston Medical Center, Boston, MA. Department of Biostatistics, Boston University School of Public Health, Boston, MA. Department of Medicine, Section of Cardiology, Boston Medical Center, Boston, MA. Department of Medicine, Section of Nephrology, Boston Medical Center, Boston, MA. Department of Neurology, Boston Medical Center, Boston, MA. Department of Medicine, Section of Pulmonary, Allergy, and Critical Care Medicine, Boston Medical Center, Boston, MA. Department of Emergency Medicine, Boston Medical Center, Boston, MA. Department of Medicine, Section of Hematology and Oncology, Boston Medical Center, Boston, MA. Department of Medicine, Section of Gastroenterology, Boston Medical Center, Boston, MA. Department of Pediatrics, Boston Medical Center, Boston, MA. Department of Quality and Patient Safety, Boston Medical Center, Boston, MA. Department of Anesthesiology, Boston Medical Center, Boston, MA. Office of the General Counsel, Boston Medical Center, Boston, MA. Department of Family Medicine, Boston Medical Center, Boston, MA. Department of Medicine, Section of Infectious Disease, Boston Medical Center, Boston, MA. Department of Neurosurgery, Boston Medical Center, Boston, MA.

Objectives: The coronavirus disease 2019 pandemic has overwhelmed healthcare resources even in wealthy nations, necessitating rationing of limited resources without previously established crisis standards of care protocols. In Massachusetts, triage guidelines were designed based on acute illness and chronic life-limiting conditions. In this study, we sought to retrospectively validate this protocol to cohorts of critically ill patients from our hospital. Read More

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The Implementation of Home Office Work in a Large Psychiatric University Hospital in Switzerland during the Covid-19 Pandemic: A Field Report.

JMIR Ment Health 2021 May 31. Epub 2021 May 31.

University Psychiatric Clinics Basel (UPK), University of Basel, Basel, CH.

Background: During the Covid-19 pandemic in 2020, psychiatric hospitals all over the world had to adapt their services to the prevailing governmental regulations. As a consequence, home office (HO) and telepsychiatry boomed.

Objective: To evaluate the potential of HO use, its adoption, and the association of HO use with employees' mental health in a large Psychiatric University Hospital in Switzerland. Read More

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COVID-19 crisis and increased risks of elder abuse in caregiving spaces.

Glob Public Health 2021 Jun 11:1-5. Epub 2021 Jun 11.

Aging and Development Unit, African Population and Health Research Center, Nairobi, Kenya.

This paper discusses the potential abuse and mistreatment against older adults by informal caregivers during the COVID-19 pandemic in Africa. The COVID-19 pandemic has distorted many informal caregivers' roles, which require serious adjustment for reducing caregiving stress and burden. Moreover, the COVID-19 pandemic has created challenging situations in caregiving spaces, which have the tendency to cause informal caregivers to abuse older adults. Read More

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Evaluation of microfiber release from jeans: the impact of different washing conditions.

Environ Sci Pollut Res Int 2021 Jun 11. Epub 2021 Jun 11.

Textile Chemistry, Department of Bioproducts and Biosystems, Aalto University, Espoo, 02150, Finland.

Microplastic particles are a burgeoning population crisis in the marine environment. This research examines the emission of microfibers from three different jeans (garments) during domestic washing. The jeans types, washing temperature, washing duration, spin speed, detergent types, and addition of conditioner are the main factors for this research work. Read More

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Exploring Internal Medicine Interns' Educational Experiences on Opioid Addiction: A Narrative Analysis.

Health Commun 2021 Jun 11:1-8. Epub 2021 Jun 11.

Department of Communication Studies, Indiana University-Purdue University.

Increased efforts to educate physicians on addiction are crucial based on widespread addiction rates and the ongoing opioid crisis. Physicians in the United States hesitate to adopt medication-assisted treatment (MAT) due to a lack of addiction education. For this study, we used a narrative framework to understand how internal medicine interns (first-year residents) recount their educational experiences on addiction during their medical school education and early residency. Read More

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'The world somehow stopped moving': impact of the COVID-19 pandemic on adolescent psychiatric outpatients and the implementation of teletherapy.

Child Adolesc Ment Health 2021 Jun 11. Epub 2021 Jun 11.

Department of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria.

Background: The COVID-19 pandemic results in disproportional consequences for psychiatric patients. Due to restraints in physical contacts, providers switched from face-to-face contacts to teletherapy, but prior experiences were mostly limited. The study aimed at assessing symptom dynamics, potentially increased adversities and factors influencing a successful transition into teletherapy in adolescent psychiatric outpatients during the COVID-19 pandemic. Read More

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Examining Recent Trends in the Racial Disparity Gap in Tap Water Consumption: NHANES 2011-2018.

Public Health Nutr 2021 Jun 11:1-20. Epub 2021 Jun 11.

Health Department, National Association for the Advancement of Colored People, Baltimore, MD 21215.

Objective: As tap water distrust has grown in the US with greater levels among Black and Hispanic households, we aimed to examine recent trends in not drinking tap water including the period covering the US Flint Water Crisis and racial/ethnic disparities in these trends.

Design: Cross-sectional analysis. We used log-binomial regressions and marginal predicted probabilities examined US nationally-representative trends in tap and bottled water consumption overall and by race/ethnicity. Read More

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The politics of testing positive: an autoethnography of media (mis)representations at the 'start' and 'end' of different pandemics.

Authors:
Max Morris

Cult Health Sex 2021 Jun 11:1-15. Epub 2021 Jun 11.

Department of Criminology and Sociology, Kingston University, Kingston-Upon-Thames, UK.

This paper draws on an autoethnographic 'digital diary' which the author began after testing positive for HIV in July 2016, until May 2021, to critically assess (mis)representations of both the AIDS and COVID-19 pandemics in the media. Drawing on insights from art, literature, queer theory and social anthropology, the paper focuses on dominant moral and political discourses to show how narratives of blame, shame and guilt about viral transmission contribute to the stigmatisation of 'at risk' groups. Concepts of biopower and normative judgement are used to reflect on discourses which construct those who 'test positive' for HIV or SARS-CoV-2 as 'reckless', 'risky' or 'irresponsible' subjects. Read More

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Building capacity in times of crisis: Increasing cultural competence of healthcare professionals in the context of the COVID-19.

J Clin Nurs 2021 Jun 10. Epub 2021 Jun 10.

Department of Nursing, Recanati School for Community Health Professions, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

Background: Nurses are the frontline healthcare professionals fighting the medical and social effects of the current COVID-19 pandemic. Although they work with diverse populations, there is a lack of literature on culturally competent education during an emergency such as a pandemic.

Aims And Objectives: To examine the effectiveness of an online education programme aimed at increasing cultural competence among rescue teams and healthcare professionals facing the challenges of the COVID-19 pandemic. Read More

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COVID-19 and Immunothrombosis: emerging understanding and clinical management.

Br J Haematol 2021 Jun 10. Epub 2021 Jun 10.

Department of Clinical Infection, Microbiology and Immunology, University of Liverpool, Liverpool, UK.

The COVID-19 pandemic has been the most significant health crisis in recent global history. Early studies from Wuhan highlighted COVID-19-associated coagulopathy and a significant association with mortality was soon recognised. As research continues across the world, more evidence is emerging of the cross-talk between the innate immune system, coagulation activation and inflammation. Read More

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