Search Our Scientific Publications & Authors

J Ophthalmol 2019 28;2019:6513143. Epub 2019 Jan 28.

Department of Ophthalmology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

Objective: To analyze the safety and efficacy of high-myopic PRK as an alternative to LASIK surgery in patients with a high preoperative percentage tissue altered (PTA).

Design: Retrospective interventional case series.

Participants: Charts of 256 consecutive eyes that underwent PRK with application of mitomycin-C 0. Read More

J Cataract Refract Surg 2019 Feb 4. Epub 2019 Feb 4.

Department of Ophthalmology, Purpan Hospital, Toulouse, France; EA 4555, Paul Sabatier University, Toulouse, France.

Purpose: To compare the outcomes of transepithelial photorefractive intrastromal corneal crosslinking (CXL) and photorefractive keratectomy (PRK) in eyes with low myopia.

Setting: Purpan Hospital, Toulouse, France.

Design: Prospective case series. Read More

Cornea 2019 Jan 9. Epub 2019 Jan 9.

LaserVision Clinical and Research Eye Institute, Athens, Greece.

Purpose: To compare the outcomes and complications of Epi-Bowman blunt keratectomy (EBK) using a blunt epikeratome (Epi-Clear, Orca Surgical, Israel), with alcohol delamination of the corneal epithelium during photorefractive keratectomy (PRK) in contralateral eyes.

Methods: This prospective, randomized contralateral eye study included 44 eyes of 22 patients undergoing PRK for bilateral myopia or myopic astigmatism. In each patient, epithelial delimitation was performed using an Epi-Clear epikeratome EBK (EBK group) on 1 eye and diluted ethanol (EtOH) on the fellow eye (EtOH group). Read More

PLoS One 2018 14;13(12):e0208608. Epub 2018 Dec 14.

Department of Ophthalmology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

Purpose: To evaluate the predictive factors for safety and efficacy in laser refractive surgery for myopia.

Setting: A singular refractive surgery center, at a University-affiliated tertiary medical center.

Design: Retrospective cohort study. Read More

J Refract Surg 2018 Nov;34(11):726-735

Purpose: To systematically compare the efficacy, predictability, safety, postoperative haze, pain scores, and epithelial healing time of four corneal surface ablation procedures.

Methods: PubMed, Embase, Cochrane Library, and the U.S. Read More

J Cell Physiol 2019 May 11;234(5):7459-7466. Epub 2018 Nov 11.

Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania, Philadelphia, Pennsylvania.

The corneal sub-basal nerve (SBN) plexus is destroyed during photorefractive keratectomy (PRK) and its recovery is still a matter of debate. In vivo confocal microscopy (IVCM) was used to evaluate SBN plexus in 23 patients at a distance of 10-25 years (mean 15.6 years) from myopic PRK. Read More

J Refract Surg 2018 Oct;34(10):654-663

Purpose: To assess the visual outcomes, predictability, and safety of the Implantable Collamer Lens (ICL) (STAAR Surgical, Inc., Monrovia, CA) for the management of residual pseudophakic refractive error.

Methods: Forty-nine pseudophakic eyes of 40 patients in which myopic, hyperopic, or toric ICLs were implanted were retrospectively analyzed. Read More

Taiwan J Ophthalmol 2018 Jul-Sep;8(3):149-158

Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou, Taiwan.

Purpose: The aim of this study is to evaluate the effectiveness and predictability of photorefractive keratectomy (PRK) for correcting residual refractive error following cataract surgery with premium intraocular lens (IOL) implantation.

Methods: We conducted a retrospective review of the medical records of patients who received PRK for correcting residual hyperopia, myopia, and/or astigmatism due to unsatisfied uncorrected distance visual acuity (UDVA) after cataract extraction with implantation of aspheric, diffractive multifocal, or toric IOL from September 2011 to December 2017. Pre-cataract surgery, pre- and post-PRK data including UDVA, best-corrected distance visual acuity, and refractive status were analyzed. Read More

Open Ophthalmol J 2018 26;12:256-263. Epub 2018 Sep 26.

Faculty of Medicine and Health Sciences, An-Najah National University Hospital, An-Najah National University, Nablus, Palestine.

Background: Laser corneal refractive surgery suits, technology and nomograms are improving with time. This may improve the refractive and visual outcomes of the patients.

Objectives: To evaluate the safety, efficacy, stability, and predictability of wavefront-optimized photorefractive keratectomy and Laser-assisted keratomileusis in patients with myopia and myopic astigmatism over 1-year using WaveLight EX500 Excimer Laser machine. Read More

J Refract Surg 2018 Sep;34(9):604-609

Purpose: To evaluate the safety and efficacy of flap-lift LASIK performed 10 or more years after the original LASIK procedure.

Methods: All patients who were treated with flap-lift LASIK 10 or more years after primary LASIK for whom records of the primary treatment could be obtained and at least 45-day follow-up refractions after re-treatment were available were included in this study. A total of 23 eyes of 20 patients were identified. Read More

J Refract Surg 2018 Sep;34(9):590-596

Purpose: To compare contrast sensitivity among participants undergoing wavefront-guided or wavefront-optimized photorefractive keratectomy (PRK) or LASIK for the treatment of myopia or myopic astigmatism 12 months after surgery.

Methods: In a prospective, randomized clinical trial, 215 participants with myopia ranging from -0.50 to -7. Read More

J Fr Ophtalmol 2018 Sep 28;41(7):650-658. Epub 2018 Aug 28.

Inserm U968, université UPMC Paris VI, UMR S 968, CNRS, UMR 7210, 75012 Paris, France; Hôpital Robert-Debré, CHU de Reims, rue du Général Koenig, 51100 Reims, France; URCA, université de Reims-Champagne-Ardenne, Reims, France. Electronic address:

Refractive surgery is a field in constant evolution. In recent years, a new procedure has appeared under the name SMILE (Small Incision Lenticule Extraction). This technique, carried out solely with a femtosecond laser, should make it possible to better preserve corneal innervation and biomechanics. Read More

Graefes Arch Clin Exp Ophthalmol 2019 Jan 18;257(1):225-232. Epub 2018 Aug 18.

Care-Vision Laser Centers, Tel-Aviv, Israel.

Purpose: To evaluate a multiple regression-derived nomogram for myopia and myopic astigmatism photorefractive keratectomy (PRK).

Methods: Regression modeling derived a formula for spherocylindrical correction in wavefront-optimized PRK (nomogram II). Treatment outcomes between eyes with myopia and myopic astigmatism using the manufacturer's nomogram (nomogram I) in the years 2010-2013 were retrospectively compared with eyes treated using nomogram II in the years 2014-2015. Read More

BMC Ophthalmol 2018 Aug 14;18(1):198. Epub 2018 Aug 14.

Department of Ophthalmology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Backgtound: Photorefractive keratectomy (PRK) is used for a wide range of refractive errors such as low to moderate myopia, hyperopia and astigmatism. While many improvements have been made in laser application and accuracy as well as the modes of corneal flap removal, and although the results are somewhat predictable, regression of refractive errors is still a common complaint among the patients undergoing refractive surgery with Excimer Laser. We aimed to determine related factors of regression following photorefractive keratectomy (PRK) in different types of refractive errors. Read More

J Refract Surg 2018 Aug;34(8):541-546

Purpose: To evaluate the outcomes after topography-guided ablation treatment (T-CAT) for the correction of myopia and myopic astigmatism with photorefractive keratectomy (PRK).

Methods: This was a retrospective, non-comparative case series study of 25 patients (40 eyes) with low to moderate myopia with or without astigmatism who underwent topography-guided custom PRK with the Wave-Light EX500 excimer laser platform (Alcon Laboratories, Inc., Fort Worth, TX). Read More

J Refract Surg 2018 Aug;34(8):533-540

Purpose: To investigate the clinical outcomes, vector parameters, and corneal aberrations of corneal wavefront-guided (CWFG) transepithelial photorefractive keratectomy (PRK), according to epithelial thickness.

Methods: This retrospective, comparative case series study included 91 eyes (91 patients) that underwent CWFG transepithelial PRK for myopic astigmatism. Epithelial thickness was less than 50 μm in 48 patients and 60 μm or greater in 43 patients. Read More

Eye Contact Lens 2019 Mar;45(2):132-136

Joint Shantou International Eye Center (R.Z., L.S., J.L., V.J., M.Z.), Shantou, People's Republic of China; Department of Ophthalmology and Visual Sciences (R.Z., L.S., J.L., A.L., V.J., M.Z.), The Chinese University of Hong Kong, Hong Kong, People's Republic of China; and UPMC Eye Center (V.J.), University of Pittsburgh School of Medicine, Pittsburgh, PA.

Purpose: To compare the visual and refractive outcomes of transepithelial photorefractive keratectomy (Trans-PRK) and sub-Bowman femtosecond-assisted laser in situ keratomileusis (SBK).

Setting: University hospital.

Design: Retrospective, comparative study. Read More

J Refract Surg 2018 Jul;34(7):466-474

Purpose: To evaluate the outcomes of transepithelial photorefractive keratectomy (PRK) in moderate to high astigmatism with a non-wavefront-guided aberration-neutral ablation profile using SmartPulse allocation.

Methods: In this retrospective study, myopic patients with a preoperative cylinder of 2.00 diopters (D) or greater were analyzed at 3 months of follow-up. Read More

BMC Ophthalmol 2018 Jun 26;18(1):154. Epub 2018 Jun 26.

The Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemungu, Seoul, 03722, South Korea.

Background: To compare the clinical outcomes of wavefront-optimized (WFO) transepithelial photorefractive keratectomy (trans-PRK) and corneal wavefront-guided (CWFG) trans-PRK for myopic eyes with moderate to high astigmatism.

Methods: One hundred ninety-six eyes (196 patients) with moderate to high astigmatism (≥ 1.75 D) treated with WFO or CWFG trans-PRK (101 and 95 eyes, respectively) were retrospectively registered. Read More

Clin Ophthalmol 2018 6;12:1041-1048. Epub 2018 Jun 6.

Little Rock Eye Clinic, Little Rock, AR, USA.

Purpose: To present refractive outcomes from consecutive cases with the Alcon Wavelight EX500 excimer laser using photorefractive keratectomy (PRK) in patients with high myopia.

Methods: A retrospective chart review of consecutive cases of high myopic eyes (≥6.0 Diopters [D]) undergoing PRK with the Alcon Wavelight EX500 excimer laser (Alcon Laboratories, Fort Worth, TX, USA) was done. Read More

J Fr Ophtalmol 2018 Jun 15;41(6):e245-e252. Epub 2018 Jun 15.

INSERM, U968, 75012 Paris, France; UMR S 968, Institut de la Vision, University UPMC Paris VI, 75012 Paris, France; CNRS, UMR 7210, 75012 Paris, France; University Hospital Robert-Debré, rue du Général-Koenig, 51100 Reims, France; URCA, University of Reims Champagne-Ardenne, 51100 Reims, France. Electronic address:

Refractive surgery is a field in constant evolution. In recent years, a new procedure has appeared under the name SMILE (SMall Incision Lenticule Extraction). This technique, carried out solely with a femtosecond laser, should make it possible to better preserve corneal innervation and biomechanics. Read More

J Refract Surg 2018 Jun;34(6):400-407

Purpose: To compare efficacy and safety of single-step transepithelial photorefractive keratectomy (PRK) with or without mitomycin C (MMC) in patients with mild to moderate myopia.

Methods: Patients with mild to moderate myopia (≤ -5.50 diopters [D]) underwent single-step transepithelial PRK using the Amaris laser (SCHWIND eye-tech-solutions GmbH, Kleinostheim, Germany). Read More

Clin Ophthalmol 2018 30;12:783-790. Epub 2018 Apr 30.

Refractive Services, The Eye Foundation, Coimbatore, India.

Purpose: To assess the safety, efficacy, and refractive predictability of half-fluence accelerated corneal collagen crosslinking (CXL) applied concurrently with photorefractive keratectomy (PRK), and compare the results to standard PRK.

Setting: Refractive Services, The Eye Foundation, Coimbatore, India.

Design: Interventional comparative case series. Read More

Curr Opin Ophthalmol 2018 Jul;29(4):306-312

Keck School of Medicine of the University of Southern California, Los Angeles, California, USA.

Purpose Of Review: To review current concepts regarding the mechanisms of postoperative pain after photorefractive keratectomy (PRK) and review available treatment options.

Recent Findings: Many clinical studies have established the safety and efficacy of different topical and systematic therapeutic agents and techniques for the treatment of postoperative pain after PRK, especially topical nonsteroidal anti inflammatory agents and oral nonsteroidal and narcotic medications. New therapeutic agents and techniques are continuously studied, introducing new agents and comparing teh efficacy of different regimens. Read More

Int J Ophthalmol 2018 18;11(4):612-615. Epub 2018 Apr 18.

Department of Surgery, Ophthalmology Clinic, University Hospital of Messina, Messina 98124, Italy.

Aim: To evaluate the efficacy and safety of the excimer laser correction of the residual refractive errors after cataract extraction with intraocular lens (IOL) implantation in uncommon cases.

Methods: Totally 24 patients with high residual refractive error after cataract surgery with IOL implantation were examined. Twenty-two patients had a history of phacoemulsification and IOL implantation, and two had extra-capsular cataract extraction with IOL implantation. Read More

Med Hypothesis Discov Innov Ophthalmol 2018 ;7(1):1-9

HDR Research Center, Hoopes Vision, 11820 S. State Street Suite #200, Draper, UT 84020, United States.

Laser vision correction is a safe and effective method of reducing spectacle dependence. Photorefractive Keratectomy (PRK), Laser In Situ Keratomileusis (LASIK), and Small-Incision Lenticule Extraction (SMILE) can accurately correct myopia, hyperopia, and astigmatism. Although these procedures are nearing optimization in terms of their ability to produce a desired refractive target, the long term cellular responses of the cornea to these procedures can cause patients to regress from the their ideal postoperative refraction. Read More

J Ophthalmol 2018 11;2018:3120941. Epub 2018 Feb 11.

Department of Ophthalmology, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

Purpose: To determine the unknown preoperative K readings (Kpre) to be used in history-based methods, for intraocular lens (IOL) power calculation in patients who have undergone myopic photorefractive keratectomy (PRK).

Methods: A regression formula generated from the left eyes of 174 patients who had undergone PRK for myopia or for myopic astigmatism was compared with other methods in 168 right eyes. The Pearson index and paired -test were utilized for statistical analysis. Read More

Medicine (Baltimore) 2018 Mar;97(12):e0094

Rationale: Recently, some ophthalmologists performed PRK or LASEK surgeries in FFKC suspicious patients, which is supposed to prevent FFKC evolvement via fibrotic scar formation. Our report indicates that keratectasia can occur after LASEK in FFKC suspicious patients, highlighting the importance of stricter regulation of patient recruitment before the procedure and postoperative follow-up.

Patient Concerns: This is a report of a 25-year-old man with poor corrected distance visual acuity (CDVA) 6 years after LASEK. Read More

Int Ophthalmol 2018 Mar 12. Epub 2018 Mar 12.

Assuta Optic, Assuta Medical Center, Tel Aviv, Israel.

Purpose: The aim of the study was to examine the outcomes of transepithelial photorefractive keratectomy (Trans-PRK) and Femtosecond Laser-assisted in situ keratomileusis (Z-LASIK) for the correction of high myopia.

Methods: A retrospective cohort study design was used. The study group included 792 eyes with high-grade myopia (- 6. Read More

J Refract Surg 2018 Mar;34(3):171-176

Purpose: To investigate the effect of nepafenac 0.3% in a once daily dosage regarding pain and healing after photorefractive keratectomy (PRK).

Methods: This was a prospective, comparative, contralateral randomized study of 35 patients undergoing PRK for the correction of low to moderate myopia and myopic astigmatism. Read More

J Refract Surg 2018 Mar;34(3):156-163

Purpose: To comparatively investigate the clinical outcomes, vector parameters, and corneal aberrations of small incision lenticule extraction (SMILE) with a triple centration technique and corneal wavefront-guided transepithelial photorefractive keratectomy (PRK) for the correction of high astigmatism.

Methods: This retrospective, comparative case series study included 89 eyes (89 patients) that received treatment for myopia with high astigmatism (≥ 2.50 diopters) using SMILE with a triple centration technique (SMILE group; 45 eyes) and corneal wavefront-guided transepithelial PRK (transepithelial PRK group; 44 eyes). Read More

J Refract Surg 2018 Feb;34(2):106-112

Purpose: To determine predictive factors for intra-operative cyclotorsion in photorefractive keratectomy (PRK).

Methods: A retrospective statistical analysis of medical records pertaining to 3,996 eyes undergoing PRK was conducted. Outcome measures of this study were the likely existence of statistically significant relations between diverse and potentially influential factors and the occurrence of intraoperative cyclotorsion. Read More

Int Ophthalmol 2019 Feb 16;39(2):341-345. Epub 2018 Jan 16.

Faculdade de Ciências Médicas de Minas Gerais (FCMMG), Belo Horizonte, MG, Brazil.

Purpose: To compare MMC 0.002% efficacy in preventing haze after PRK in relation to MMC 0.02%. Read More

Ophthalmic Res 2018 17;59(3):135-141. Epub 2018 Jan 17.

Department of Ophthalmology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China.

Purpose: The aim of this study was to analyze the effects of corneal crosslinking (CXL) combined with phototherapeutic keratectomy (PTK) and photorefractive keratectomy (PRK) in halting the progression and improving the visual function of corneal ectasia after laser in situ keratomileusis (LASIK).

Methods: PTK-PRK-CXL was performed on 14 eyes of 14 patients who developed corneal ectasia after LASIK. The visual acuity, spherical refraction and cylinder, corneal topography indices, thinnest corneal thickness (TCT), and endothelial cell count were evaluated at baseline and at 1, 3, 6, and 12 months postoperatively. Read More

J Refract Surg 2018 Jan;34(1):59-64

Purpose: To analyze corneal persistent epithelial defects that occurred at 3 to 4 weeks after -4.50 diopter (D) photorefractive keratectomy (PRK) in rabbits and apply this pathophysiology to the treatment of persistent epithelial defects that occur after any corneal manipulations or diseases.

Methods: Two of 168 corneas that had -4. Read More

Indian J Ophthalmol 2018 01;66(1):10-19

Department of Phaco-Refractive, Nethradhama Superspeciality Eye Hospital, Bengaluru, Karnataka, India.

Small incision lenticule extraction (SMILE), a variant of refractive lenticule extraction technology is becoming increasingly popular, as a flapless and minimally invasive form of laser vision correction (LVC) for the treatment of myopia and myopic astigmatism. This review aims at summarizing the principles, surgical technique, and clinical outcomes in terms of visual and refractive results, safety, efficacy, postoperative dry eye, aberrations, and biomechanics of SMILE and its comparison with other conventional techniques of LVC, such as laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK). Recent advancements in the laser frequency and energy delivery patterns, instrumentation, and surgical techniques have shown significant improvement in the visual recovery and outcomes after SMILE, compared to the initial results published by Sekundo and Shah et al. Read More

J Refract Surg 2017 Dec;33(12):820-826

Purpose: To evaluate the postoperative asphericity in low, moderate, and high myopic eyes after combined transepithelial photorefractive keratectomy and SmartSurf treatment (SCHWIND eye-tech-solutions GmbH, Kleinostheim, Germany).

Methods: In this retrospective case series, the outcomes of myopic SmartSurf were evaluated at 3 months postoperatively in 106 eyes and divided into low (less than -4.125 diopters [D]), moderate (-4. Read More

Mil Med 2017 11;182(11):e2061-e2065

Department of Ophthalmology, San Antonio Uniformed Services Health Education Consortium, 3351 Roger Brooke Drive, San Antonio, TX 78219.

Introduction: In an attempt to maximize treatment outcomes, refractive surgery techniques are being directed toward customized ablations to correct not only lower-order aberrations but also higher-order aberrations specific to the individual eye. Measurement of the entirety of ocular aberrations is the most definitive means to establish the true effect of refractive surgery on image quality and visual performance. Whether or not there is a statistically significant difference in induced higher-order corneal aberrations between the VISX Star S4 (Abbott Medical Optics, Santa Ana, California) and the WaveLight EX500 (Alcon, Fort Worth, Texas) lasers was examined. Read More

Cornea 2018 Jan;37(1):45-52

Department of Ophthalmology, American University of Beirut, Beirut, Lebanon.

Purpose: To evaluate the epithelial erosion incidence and refractive results in myopic eyes undergoing single-step transepithelial photorefractive keratectomy (TransPRK) compared with alcohol-assisted photorefractive keratectomy (PRK).

Methods: This was a retrospective nonrandomized comparative study conducted at the American University of Beirut Medical Center. A total of 189 eyes that had undergone single-step transepithelial PRK (TransPRK) were compared with 189 matched eyes that had undergone alcohol-assisted PRK over a follow-up of 1 year. Read More

Taiwan J Ophthalmol 2017 Apr-Jun;7(2):82-88

Department of Ophthalmology, Changhua Christian Hospital, Changhua, Taiwan.

Purpose: To evaluate the efficacy, safety, predictability, and visual performance of excimer laser photorefractive keratectomy (PRK) for myopia greater than -8 diopters (D).

Methods: Fifty-four patients (104 eyes) with myopia from -8D to -13D and cylinder up to -4D received surface ablation technique with the Allegretto wave version 1009-1 excimer laser to correct their refractive error. The patients were examined on days 1, 3, 7, and 14 and 1, 3, 6, and 12 months postoperatively. Read More

Cornea 2017 Oct;36(10):1206-1212

Department of Ophthalmology, University of São Paulo Medical School General Hospital, University of São Paulo, São Paulo, Brazil.

Background: Pain after photorefractive keratectomy (PRK) is significant, and the analgesic efficacy and safety of oral opioids in combination with acetaminophen has not been fully investigated in PRK trials.

Purpose: To assess the efficacy and safety of the combination of codeine plus acetaminophen (paracetamol) versus placebo as an add-on therapy for pain control after PRK.

Study Design: Randomized, double-blind, placebo-controlled trial. Read More

J Ophthalmic Vis Res 2017 Jul-Sep;12(3):265-269

Negah Eye Center, Tehran, Iran.

Purpose: To determine changes in stereoacuity in anisometropic myopic eyes after photorefractive keratectomy (PRK).

Methods: Myopic patients with at least 1 diopter (D) of anisometropia in sphere, astigmatism, or spherical equivalent who were referred to our hospital for excimer refractive surgery were enrolled as a prospective sequential interventional case series. All patients underwent wavefront-guided photorefractive keratectomy (WFG-PRK) using the Technolas Perfect Vision (217z) Excimer laser machine. Read More

J Ophthalmic Vis Res 2017 Jul-Sep;12(3):254-259

Department of Medical Education, School of Medical Education, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Purpose: To compare the corneal power measurements obtained using different topographic instruments after myopic photorefractive keratectomy (PRK).

Methods: Patients with myopia who were candidates for corneal refractive surgery were sequentially included. Pre-PRK and six months post-PRK corneal powers were measured using Javal manual keratometer, Orbscan II, Galilei, Tomey TMS4, and EyeSys 2000 topographers. Read More

J Curr Ophthalmol 2017 Jun 4;29(2):98-102. Epub 2017 Feb 4.

Department of Ophthalmology, Faculty of Medicine Building, University of Malaya, Kuala Lumpur, Malaysia.

Purpose: To evaluate the effect of non-keratometric ocular astigmatisms on visual and refractive outcomes after photorefractive keratectomy (PRK) for correction of myopic astigmatisms.

Methods: Seventy one eyes of 36 subjects were enrolled in this study. Patients underwent PRK for treatment of myopia. Read More

Eye (Lond) 2017 Dec 16;31(12):1647-1654. Epub 2017 Jun 16.

Innova Ocular, Madrid, Spain.

PurposeThe aim of this study was to gain greater insight into the corneal densitometry changes occurring as a result of refractive surgery and to compare these changes across three widely used surgical techniques, namely, photorefractive keratectomy (PRK), laser-assisted in situ keratomileusis with a femtosecond laser (LASIK-FS), or ReLEx small-incision lenticule extraction (ReLEx SMILE).Patients and methodsThree hundred and thirty-six patients (184 male and 152 female patients) participated in this study. They were split into three groups according to the refractive surgery technique they had undergone: LASIK-FS (74 patients), PRK (153 patients), and ReLEx SMILE (109 patients). Read More

Int Ophthalmol 2018 Jun 13;38(3):1211-1217. Epub 2017 Jun 13.

Eye Research Center, Khatam Eye Hospital, Mashhad University of Medical Sciences, Mashhad, 9195965919, Iran.

Purpose: To compare differences in the endothelial cells before and after photorefractive keratectomy (PRK) for myopia with refractive error graded mitomycin C (MMC) application.

Methods: In a prospective randomized clinical trial, forty-eight myopic patients referred to Khatam-al-Anbia Eye Hospital, Mashhad, Iran, for PRK. Patients were treated with PRK by a Bausch and Lomb Technolas 217z excimer laser (Bausch and Lomb, Rochester, NY). Read More

Int Ophthalmol 2018 Jun 27;38(3):1147-1154. Epub 2017 May 27.

Nethradhama Superspeciality Eye Hospital, 256/14, Kanakapura Main Road, 7th Block, Jayanagar, Bengaluru, Karnataka, 560070, India.

Purpose: To compare the objective and subjective quality of vision after femtosecond laser-assisted small incision lenticule extraction (SMILE) and photorefractive keratectomy (PRK) for low myopia.

Methods: One hundred and twenty eyes from 60 patients (34 females, 26 males) undergoing bilateral correction of low myopia (≤-4 D SE) with either ReLEx SMILE or PRK were included. Visual acuity, contrast sensitivity and higher-order aberrations were recorded preoperatively and compared postoperatively. Read More

Cornea 2017 Aug;36(8):961-966

*Department of Ophthalmology, Barzilai University Medical Center, Ashkelon, Israel; †Faculty of Health Sciences, Ben-Gurion University of the Negev, Be'er Sheva, Israel; ‡Care Vision Laser Centers, Tel Aviv, Israel; and §Department of Ophthalmology, Rambam Health Care Campus, Haifa, Israel.

Purpose: To identify preoperative and intraoperative factors affecting breakthrough corneal haze incidence after photorefractive keratectomy (PRK) with mitomycin C (MMC).

Methods: In this retrospective study of PRK performed at the Care Vision Refractive Laser Center, Tel Aviv, Israel, a total of 7535 eyes (n = 3854 patients; mean age ± SD, 26 ± 6 years; 55% men) underwent PRK with intraoperative MMC application. Patients with histories of corneal pathology or surgery were excluded. Read More