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Medicine (Baltimore) 2022 Jun 17;101(24):e29425. Epub 2022 Jun 17.

Department of Ophthalmology, Fuyang People's Hospital of Anhui Medical University, Fuyang, Anhui, China.

Purpose: To explore the offset distribution of pupillary centres, the offset between the pupil centre and the coaxially sighted corneal light reflex (P-Dist) and their correlation in femtosecond laser combined with excimer laser in situ keratomileusis.

Methods: Randomly selected 194 patients (398 eyes) who underwent femtosecond-assisted laser in situ keratomileusis with preoperative use of WaveLight Allegro Topolyzer Corneal Topography (WaveLight Laser Technologies AG, Erlangen, Germany) to measure the pupil size and centre position. The P-Dist of the patients was recorded by the X and Y axis eyeball tracking adjustment program of the WaveLight Eagle Vision EX500 excimer laser system. Read More

Transl Vis Sci Technol 2022 Jun;11(6):13

Tianjin Medical University Eye Hospital, College of Optometry, Institute of Ophthalmology, National Clinical Medical Research Center for Eye, Ear, Nose and Throat Diseases, Tianjin Branch, Tianjin Key Laboratory of Retinal Function and Diseases, Tianjin, China.

Purpose: The purpose of this study was to explore the characteristics of pupil offset in young Asian adults with myopia.

Methods: In total, 1200 eyes (600 young adults, 18-35 years old) were divided into mild-moderate and high groups according to equivalent spherical diopters (SEQ). The pupil offset and its X and Y components were compared between the groups. Read More

Int Ophthalmol 2022 May 30. Epub 2022 May 30.

Tianjin Medical University Eye Hospital, College of Optometry, Institute of Ophthalmology, National Clinical Medical Research Center for Eye, Ear, Nose and Throat Diseases, Tianjin Branch, Tianjin Key Laboratory of Retinal Function and Diseases, Tianjin, 300384, China.

Purpose: To compare changes in asphericity of anterior and posterior corneal surfaces for different myopia patients after corneal topography-guided femtosecond-assisted laser in situ keratomileuses (FS-LASIK), and to analyze correlations between asphericity of corneal surfaces and preoperative spherical equivalence (SEQ).

Methods: In this prospective study, 59 patients who underwent corneal topography-guided FS-LASIK surgery were enrolled and divided into the mild-moderate myopia group (67 eyes) and the high myopia group (44 eyes). Postoperative follow-ups were performed at 1, 3, and 6 months. Read More

BMC Ophthalmol 2022 May 23;22(1):234. Epub 2022 May 23.

Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China.

Background: To compare the quantitative and qualitative optical outcomes of single-step transepithelial photorefractive keratectomy (TPRK) and off-flap epipolis-laser in situ keratomileusis (Epi-LASIK) in moderate to high myopia.

Methods: In this prospective self-control study, we included patients with moderate to high myopia who were randomized to undergo TPRK in one eye and Epi-LASIK in the other eye. Twelve-month follow-up results for visual acuity, refraction, ocular high-order aberrations, contrast sensitivity, postoperative pain, epithelial healing, and haze grade were assessed. Read More

Am J Ophthalmol 2022 May 17. Epub 2022 May 17.

Byers Eye Institute, Department of Ophthalmology, Stanford University School of Medicine, Palo Alto, California. Electronic address:

Purpose: To prospectively compare corneal sensation and patient-reported symptoms of dry eye in individuals undergoing laser-assisted in situ keratomileusis (LASIK) and small incision lenticule extraction (SMILE).

Design: Prospective randomized contralateral-eye clinical trial.

Methods: 80 eyes of 40 patients with myopia at Byers Eye Institute at Stanford University were randomized to receive wavefront-guided femtosecond LASIK in one eye and SMILE in the fellow eye. Read More

J Refract Surg 2022 May 1;38(5):288-297. Epub 2022 May 1.

Purpose: To report 6-month visual and refractive outcomes following PRESBYOND Laser Blended Vision (Carl Zeiss Meditec) treatment using non-linear aspheric micro-anisometropia laser in situ keratomileusis (LASIK) for the correction of myopic and hyperopic presbyopia.

Methods: A retrospective, non-comparative study of 139 consecutive patients with a mean age of 53.13 ± 5. Read More

Acta Ophthalmol 2022 May 9. Epub 2022 May 9.

Hospital Lluís Alcanyís, Xàtiva, Spain.

Systematic reviews (SRs) and meta-analyses (MAs) are of great importance for basing clinical decisions. However, misleading interpretations may result when informed decisions rest on biased review papers with methodological issues. To evaluate which treatment is optimal, an overview was made of SRs and MAs to establish the quality and certainty of meta-evidence published on the efficacy of laser-based refractive surgery techniques for treating myopia in adults. Read More

Ophthalmol Ther 2022 May 9. Epub 2022 May 9.

Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, No. 270 Xueyuan West Road, Wenzhou, 325027, Zhejiang, China.

Introduction: This study evaluated the outcomes of laser in situ keratomileusis (LASIK) combined with prophylactic corneal collagen cross-linking (CXL) in correcting myopia in cases with increased estimated risk of postoperative corneal ectasia, detected by regional analysis of corneal morphology.

Methods: The retrospective study included 180 eyes of 99 patients. Group 1 (94 eyes of 49 patients) with increased risk of postoperative corneal ectasia, as detected by "Ectasia Risk Factor Score System for LASIK", underwent femtosecond laser-assisted LASIK (FS-LASIK) combined with prophylactic CXL, using short riboflavin soaking time and low UV energy. Read More

Sci Rep 2022 05 5;12(1):7357. Epub 2022 May 5.

Loma Linda University Eye Institute, 11370 Anderson Street, Suite 1800, Loma Linda, CA, 92354, USA.

To compare the predictive refractive accuracy of intraoperative aberrometry (ORA) to the preoperative Barrett True-K formula in the calculation of intraocular lens (IOL) power in eyes with prior refractive surgery undergoing cataract surgery at the Loma Linda University Eye Institute, Loma Linda, California, USA. We conducted a retrospective chart review of patients with a history of post-myopic or hyperopic LASIK/PRK who underwent uncomplicated cataract surgery between October 2016 and March 2020. Pre-operative measurements were performed utilizing the Barrett True-K formula. Read More

Front Bioeng Biotechnol 2022 11;10:855367. Epub 2022 Apr 11.

College of Biomedical Engineering, Taiyuan University of Technology, Taiyuan, China.

Myopia, which is the result of the uncoordinated development of the eyeball, has become a major public health focus worldwide. Laser keratomileusis (LASIK) and small-incision lenticule extraction (SMILE) have been successfully used in modern corneal refractive surgery. However, there are still controversies about postoperative results of LASIK and SMILE. Read More

BMC Ophthalmol 2022 Apr 25;22(1):189. Epub 2022 Apr 25.

FPS-IMIP, Av Mal. Mascarenhas de Morais, Recife, PE, 4861, Brazil.

Background: Wavefront-optimized laser-assisted in situ keratomileusis (LASIK) ablation is the most commonly performed procedure in refractive surgery, but new technologies have become available. Our goal was to compare topography-guided (Contoura) and asphericity-guided (Custom-Q) customized ablation treatments for the correction of myopia with or without astigmatism.

Methods: This prospective, randomized, double-blind, contralateral eye study included 60 eyes of 30 patients with myopia or myopic astigmatism requiring femtosecond LASIK (FemtoLASIK) treatment. Read More

Front Med (Lausanne) 2022 8;9:814810. Epub 2022 Apr 8.

Department of Ophthalmology, Eye Institute, Eye and ENT Hospital, Fudan University, Shanghai, China.

Purpose: To evaluate the outcomes in corneal higher-order aberrations (HOAs) and microdistortions in the Bowman's layer after femtosecond laser small incision lenticule extraction (SMILE) for correcting extremely high myopia.

Methods: This prospective study included patients with myopia with spherical equivalent ≥ -9.0 Diopters (D). Read More

Front Med (Lausanne) 2022 5;9:870330. Epub 2022 Apr 5.

Department of Ophthalmology, Peking University Third Hospital, Beijing, China.

Purpose: To compare visual outcomes and corneal optical quality after small incision lenticule extraction (SMILE), wavefront-optimized (WFO) FS-LASIK, and topography-guided customized ablation treatment (TCAT) FS-LASIK for myopia.

Methods: This prospective case-series study included 283 eyes of 283 myopic patients who underwent SMILE or FS-LASIK. There were 102, 100, and 81 eyes in the SMILE group, WFO group and TCAT group, respectively. Read More

J Refract Surg 2022 Apr 1;38(4):235-242. Epub 2022 Apr 1.

Purpose: To compare the clinical outcomes after topography-guided and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) planned with the Phorcides Analytic Engine (PAE) algorithm system and Sirius tomography data for correction of myopia and myopic astigmatism when the ocular residual astigmatism (ORA) was great or not.

Methods: In this retrospective study, a total of 163 eyes with myopia and myopic astigmatism (99 patients) were included. Eyes with myopic astigmatism and high ORA of 0. Read More

J Refract Surg 2022 Apr 1;38(4):277-284. Epub 2022 Apr 1.

Purpose: To compare postoperative corneal sub-basal nerve density and number between small incision lenticule extraction (SMILE) and femtosecond laser-assisted in situ keratomileusis (FS-LASIK).

Methods: A search was made in PubMed, EMBASE, and the Cochrane library for prospective comparative studies. The analysis was divided into two parts: network meta-analysis and traditional meta-analysis of the studies directly comparing two surgical groups. Read More

Zhonghua Yan Ke Za Zhi 2022 Apr;58(4):303-308

Affiliated Eye Hospital of Nanchang University, Nanchang 330006, China.

Small incision lenticule extraction (SMILE) is a new technique that exhibits excellent efficacy, safety and predictability for the correction of myopia and myopic astigmatism. However, one potential limitation of this technique is that the centration during femtosecond laser cutting might be subject to the surgeon's experience and patient's cooperation. To achieve accurate centration in SMILE is the key to obtaining good postoperative visual outcomes. Read More

Cornea 2022 May;41(5):640-643

NVISION Eye Centers, Rowland Heights, CA.

Purpose: The purpose of this study was to report an isolated case of 2 siblings who developed central toxic keratopathy (CTK) after undergoing laser-assisted keratomileusis (LASIK) on the same day.

Methods: This was a case report and literature review.

Results: Two sisters with no significant medical history underwent uncomplicated LASIK on the same day. Read More

Cornea 2022 May;41(5):604-608

Siena Eye Laser, Poggibonsi, Siena, Italy.

Purpose: The purpose of this article was to evaluate the prognosis of traumatic flap dislocation or avulsion in a large series of laser-assisted in situ keratomileusis (LASIK) cases.

Methods: Retrospective, consecutive, noncomparative case series analyzes the visual and anatomical results after flap dislocation or avulsion, caused by trauma occurred at least 1 month after LASIK.

Results: A total of 37,315 eyes of 19,602 patients were reviewed. Read More

J Cataract Refract Surg 2022 Mar 29. Epub 2022 Mar 29.

Department of Ophthalmology and Optometry, Eye and ENT Hospital, Fudan University, Shanghai, China; NHC Key Laboratory of Myopia (Fudan University), Shanghai, China; Shanghai Research Center of Ophthalmology and Optometry.

Purpose: To evaluate the incidence, causes, and outcomes of Implantable Collamer Lens (ICL) re-alignment or exchange following implantation of the EVO ICL.

Setting: Eye and ENT Hospital of Fudan University, China.

Design: Retrospective study. Read More

J Cataract Refract Surg 2022 Mar 24. Epub 2022 Mar 24.

Byers Eye Institute Stanford, University School of Medicine, Palo Alto, CA 94303.

Purpose: To assess the effect of epithelial remodeling on visual outcomes over a 9 mm diameter corneal surface following topography-guided laser in-situ keratomileusis (LASIK) for myopia correction using spectral-domain anterior segment optical coherence tomography (AS-OCT).

Setting: Outpatient clinical practice at the Stanford University Byers Eye Institute in Palo Alto, California, USA.

Design: Prospective non-randomized observational study. Read More

Eye Contact Lens 2022 Jun 24;48(6):239-241. Epub 2022 Mar 24.

OnO (M.R., A.A.d.B., U.B., D.A.K., N.S.-H.J.B.), Ophthalmology Network Organisation, Clinique de l'Oeil SA, Onex, Geneva, Switzerland; and Miramichi EyeNB Centre of Excellence (N.S.-H.), Miramichi, NB, Canada.

Objectives: To assess the impact of posterior corneal asphericity on postoperative calculation error using the Haigis-L and the Barrett formulas for eyes after laser in situ keratomileusis or photorefractive keratectomy (PRK).

Methods: We assessed the mean absolute error (MAE) of two power calculation formulas, Barrett true-K and Haigis-L formulas, in a retrospective analysis of 34 eyes of 34 patients who underwent cataract surgery. We performed a regression analysis between corneal parameters (anterior and posterior Q values, Kmax, K1, and K2) and the MAE of each formula. Read More

Klin Monbl Augenheilkd 2022 Apr 23;239(4):382-385. Epub 2022 Mar 23.

Augenklinik, Luzerner Kantonsspital, Luzern, Switzerland.

Background: To evaluate 10-year long-term refractive visual stability and participants' satisfaction in the refractive treatment of myopic eyes undergoing topography-guided transepithelial surface ablation using a 1KHz excimer laser.

Patients And Methods: This single-center prospective survey assessed participants' satisfaction 10 years after the treatment using a non-validated questionnaire with regards to visual outcome, dry eye, and visual disturbance symptoms. Pre- and postoperative visual and refractive data were evaluated. Read More

Int J Ophthalmol 2022 18;15(3):502-509. Epub 2022 Mar 18.

Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin 300384, China.

Aim: To compare the changes in the objective visual quality of patients with low and moderate myopia postoperatively after transepithelial photorefractive keratectomy using the smart pulse technology (SMART) and femtosecond laser keratomileusis (FS-LASIK).

Methods: Corneal higher-order aberrations (HOAs), horizontal coma, vertical coma and spherical aberration were measured using Pentacam, and cutoff for modulation transfer function (MTF cutoff), objective scatter index (OSI) and Strehl ratio (SR) was measured using an optical quality analysis system (OQAS-II), before and after operation at 1, 3, and 6mo, and data were analyzed by repeated measurement two-way analysis of variance.

Results: The difference in uncorrected distance visual acuity between SMART and FS-LASIK was statistically significant only 1wk postoperatively. Read More

Ophthalmol Ther 2022 Jun 9;11(3):1047-1066. Epub 2022 Mar 9.

Clínica Rementería, Madrid, Spain.

Introduction: To compare the influence of one microkeratome and three femtosecond lasers on myopic laser in situ keratomileusis (LASIK) outcomes.

Methods: Retrospective, observational cohort study. We compared 134 eyes treated with the IntraLase 60 kHz, 112 eyes treated with the Femto LDV Z6, 206 eyes treated with the FS200, and 98 eyes treated with the Hansatome zero compression microkeratome. Read More

Graefes Arch Clin Exp Ophthalmol 2022 Mar 9. Epub 2022 Mar 9.

NewVision Clinics, Melbourne, Australia.

Purpose: To demonstrate how hemidivisional vector planning of refractive laser treatments of astigmatism can be used to directly address idiopathic corneal irregular astigmatism that has an asymmetrical, non-orthogonal bow tie topography appearance.

Design: Case study.

Methods: The cornea is conceptually divided into two hemidivisions along the flat meridian of the corneal topographic astigmatism (CorT), which means that each hemidivision will approximately correspond to one lobe of the asymmetric, non-orthogonal topographic bow tie. Read More

Indian J Ophthalmol 2022 Mar;70(3):1073

Khatib Eye Clinic, Mumbai, Maharashtra, India.

Background: Topography guided laser-assisted in situ keratomileusis (LASIK) has always been some sort of an enigma in terms of its understanding and interpretation. Contoura LASIK is one such form of FDA approved topography guided LASIK on the Wavelight platform for virgin eyes. Inspite of promising so much, its complete application has not yet been fully understood and cannot be applied for all cases. Read More

Clin Ophthalmol 2021 22;15:4775-4785. Epub 2021 Dec 22.

Chiang Mai University LASIK Center, Center for Medical Excellence, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

Purpose: To evaluate the 12-months outcomes of photorefractive keratectomy (PRK) in patients with high myopia (≥ 6.0 diopters, D) compared with low-to-moderate myopia (< 6.0 D). Read More

Curr Eye Res 2022 Jun 14;47(6):824-831. Epub 2022 Mar 14.

Ophthalmology Department, Civil Aviation Medical Center, Beijing, China.

Purpose: To record the long-term visual quality after FS-LASIK and analyze the effect of long-term refractive regression after corneal laser surgery on visual quality.

Methods: Seventy-eight patients (153 eyes) who had undergone FS-LASIK more than 5 years before and had undergone follow-ups between November 2020 and March 2021. We collected data on the patients' age of surgery, postoperative period, and preoperative diopters (corrected to LogMAR 0. Read More

J Cataract Refract Surg 2022 Feb 10. Epub 2022 Feb 10.

Woolfson Eye Institute, 800 Mt. Vernon Hwy., NE, Suite 120, Atlanta, GA 30328, American Corneal Consultants, 15 Island Rd., North Oaks, MN 55127, Mann Eye Institute and Laser Centers, 5115 Main St, Suite#300, Houston, Texas 77002, TLC Laser Eye Center, 16305 Swingley Ridge Rd, Suite 375, Chesterfield MO 63017-1777 , 1002 N Church Street, Suite 101, Greensboro NC 27401, Science in Vision, 127 NW Revere Ave, Bend, OR 97703,

Purpose: To evaluate prospectively the clinical outcomes of topography-guided laser in situ keratomileusis (LASIK) surgery performed with Contoura® Vision using the Wavelight® excimer laser and planned with the Phorcides Analytical Engine.

Setting: Four clinical practices in the USA.

Design: Prospective, single-arm interventional study. Read More

J Cataract Refract Surg 2022 Feb 10. Epub 2022 Feb 10.

School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium Department of Ophthalmology, Antwerp University Hospital, Edegem, Belgium ELZA Institute, Dietikon, Switzerland Ocular Cell Biology Group, Center for Applied Biotechnology and Molecular Medicine, University of Zurich, Switzerland Department of Ophthalmology, University of Southern California, Los Angeles, CA, USA Faculty of Medicine, University of Geneva, Geneva, Switzerland.

Purpose: To assess the repeatability of several corneal biomechanical parameters with a Scheimpflug tonometer (Corvis ST) in myopic eyes and eyes that underwent Transepithelial Photorefractive Keratectomy (TransPRK), Small-Incision Lenticule Extraction (SMILE), or Femtosecond Laser-Assisted In Situ Keratomileusis (FS-LASIK) surgery.

Setting: Eye Hospital of Wenzhou Medical University, Wenzhou, China.

Design: Prospective, randomized controlled study. Read More