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    17956 results match your criteria Myocarditis

    1 OF 360

    Parvovirus B19-induced vascular damage in the heart is associated with elevated circulating endothelial microparticles.
    PLoS One 2017 22;12(5):e0176311. Epub 2017 May 22.
    Klinik für Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum des Saarlandes, Homburg/ Saar, Universität des Saarlandes, Saarlandes, Germany.
    Background: Diagnosis of viral myocarditis is difficult by clinical criteria but facilitated by detection of inflammation and viral genomes in endomyocardial biopsies. Parvovirus B19 (B19V) targets endothelial cells where viral nucleic acid is exclusively detected in the heart. Microparticles (MPs) are released after cell damage or activation of specific cells. Read More

    First report of Angiostrongylus vasorum in a wild red fox (Vulpes vulpes) from Apulia (Italy).
    Vet Ital 2017 Apr 5. Epub 2017 Apr 5.
    University of Bari, Department of Veterinary Medicine, 70010 Valenzano (BA), Italy.
    Severe lung strongylosis was detected in a wild red fox (Vulpes vulpes) (1/12) from Apulia (Italy). We performed routine diagnostics on 12 foxes found dead in Apulia. Eleven of them showed lesions consistent with a vehicle collision. Read More

    Myocardial edema in acute myocarditis: relationship of T2 relaxometry and late enhancement burden by using dual-contrast turbo spin-echo MRI.
    Int J Cardiovasc Imaging 2017 May 20. Epub 2017 May 20.
    University Hospital for Radiology, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
    To quantify myocardial edema by using a T2 relaxometry approach with a dual-contrast turbo spin-echo (dcTSE) sequence in patients with acute myocarditis regarding focal late gadolinium enhancement (LGE) burden. CMR T2 relaxometry was performed in 39 patients (age 41 ± 19 years; 36% women) with LGE in a typical myocarditis pattern and in ten healthy volunteers (age 46 ± 12; 60% woman). dcTSE sequence (echo time 29 and 75 ms, respectively) was used for T2 mapping, analysis were performed on the basis of region of interest (ROI). Read More

    Oleuropein prevents the development of experimental autoimmune myocarditis in rats.
    Int Immunopharmacol 2017 May 16;48:187-195. Epub 2017 May 16.
    Department of Critical Care Medicine, Hang Zhou Red Cross Hospital, Hangzhou 310014, Zhejiang, China. Electronic address:
    Oleuropein (OLE) is a natural secoiridoid that is derived from Olea europaea. OLE possesses cardioprotective effects in experimental models of hypertension, myocardial infarction, atherosclerosis and hyperlipidaemia. In the present study, the effects of OLE on experimental autoimmune myocarditis (EAM) were evaluated. Read More

    Clinical signs, diagnostics and successful treatment of a myocarditis in an adult chimpanzee (Pan troglodytes).
    J Med Primatol 2017 May 19. Epub 2017 May 19.
    Department of Cardiology, Heartcenter, OLVG, Amsterdam, The Netherlands.
    A chimpanzee (Pan troglodytes) was presented with lethargic behaviour. Echocardiography and abnormal cardiac and inflammatory biomarkers revealed a myocarditis. The animal fully recovered after prolonged treatment with losartan and carvedilol. Read More

    Acute Myocarditis Secondary to Reactivated Chromosomally-Integrated HHV6.
    J Card Fail 2017 May 15. Epub 2017 May 15.
    Section of Cardiology, University of Chicago, Chicago, IL.. Electronic address:
    ciHHV-6 (chromosomally-integrated HHV-6) is an uncommon cause of myocarditis but may be underdiagnosed. We describe a case of reactivated ciHHV-6 myocarditis successfully treated with antiviral therapy. Our case demonstrates the need for a greater awareness of ciHHV-6 as an etiology of myocarditis, as prompt treatment can improve outcomes. Read More

    Cardiovascular involvement and manifestations of systemic Chikungunya virus infection: A systematic review.
    F1000Res 2017 29;6:390. Epub 2017 Mar 29.
    Public Health and Infection Research Group, Faculty of Health Sciences, Universidad Tecnológica de Pereira, Pereira, Risaralda, Colombia.
    Background: In the last three years, chikungunya virus disease has been spreading, affecting particularly the Americas, producing more than two million cases. In this setting, not only new disease-related epidemiological patterns have been found, but also new clinical findings have been reported by different research groups. These include findings on the cardiovascular system, including clinical, electrocardiographic and echocardiographic alterations. Read More

    Mid-term Risk for Subclinical Atherosclerosis and Chronic Myocarditis in Children with Kawasaki Disease and Transient Coronary Abnormalities.
    Pediatr Cardiol 2017 May 17. Epub 2017 May 17.
    Department of Cardiology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.
    There is evidence for premature atherosclerosis and systemic arterial stiffening during follow-up of children with Kawasaki disease (KD) and coronary artery abnormalities (CAA). Moreover, patients with KD may also have subclinical myocardial involvement and inhomogeneous ventricular repolarization. The inhomogeneous ventricular repolarization manifests as increased QT dispersion on electrocardiography. Read More

    The role of the persistent enterovirus infection in development of acute stroke.
    Wiad Lek 2017 ;70(2):187-191
    O.O. BOGOMOLETS NATIONAL MEDICAL UNIVERSITY, KYIV, UKRAINE.
    Introduction: The role of enteroviruses in development of dilated cardiomyopathy, myocardial infarction, myocarditis, pericarditis is known.

    The Aim: To examine the role of chronic enterovirus infections in development of acute stroke.

    Material And Methods: Blood samples from 72 patients with acute stroke (study group) and 35 patients without vascular disease (control group) were investigated by reverse transcription polymerase chain reaction for the presence of enterovirus RNA, by using virological method to detect enteroviruses, by ELISA for the levels of IgM and IgG antibodies to enteroviruses. Read More

    Yield of Cardiac Magnetic Resonance Imaging in Patients With Acute Coronary Syndrome and No Obstructive Coronary Artery Disease.
    Crit Pathw Cardiol 2017 Jun;16(2):58-61
    From the *Providence Health Care Research Institute, Vancouver, British Columbia, Canada; and †Vancouver General Hospital, Vancouver, British Columbia, Canada.
    Purpose: Ten percent to 25% of women and 6%-10% of men with acute coronary syndrome (ACS) are found to have no obstructive coronary artery disease (CAD) on coronary computed tomography angiogram or invasive coronary angiography. The etiology of presentation is often unclear. We examined the diagnostic yield of cardiac magnetic resonance imaging (CMR) in patients with signs and symptoms suggestive of an ACS and no obstructive CAD. Read More

    Inhibition of 12/15-LO ameliorates CVB3-induced myocarditis by activating Nrf2.
    Chem Biol Interact 2017 May 12;272:65-71. Epub 2017 May 12.
    Department of Cardiovascular Surgery, Henan Provincal People's Hospital, Zhengzhou 450000, China. Electronic address:
    Cardiac 12/15-lipoxygenase (12/15-LO) was reported to be markedly up-regulated and involved in the development of heart failure. Nuclear factor E2-related factor 2 (Nrf2) plays anti-inflammatory and anti-oxidation roles in response to oxidative stress. However, the role of 12/15-LO in viral myocarditis (VMC) and its underlying molecular mechanism have not yet been elucidated. Read More

    Successful clozapine re-challenge following myocarditis.
    Australas Psychiatry 2017 May 1:1039856217707394. Epub 2017 May 1.
    Consultant Psychiatrist, Cramond Clinic, The Queen Elizabeth Hospital, Woodville, SA, Australia.
    Objective: To explore the evidence around clozapine re-challenge following myocarditis.

    Conclusion: This case adds to the 17 cases of clozapine re-challenge following myocarditis, of which 71% were successful (12 cases). This demonstrates that re-challenge could be performed safely and effectively in the context of clozapine-induced myocarditis, if accompanied by a strict and rigorous monitoring protocol. Read More

    Sudden death in a pediatric heart transplant recipient with peripheral eosinophilia and eosinophilic myocardial infiltrates.
    Pediatr Transplant 2017 May 14. Epub 2017 May 14.
    Department of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, TN, USA.
    Eosinophilia has been rarely reported in pediatric heart transplant recipients and has been suggested to play a role in graft rejection. We report a case of a young female patient with peripheral blood eosinophilia who died suddenly 2 years following ABO-incompatible heart transplantation. She was found at autopsy to have myocardial infiltration of not only T-lymphocytes and macrophages expected in acute cellular rejection but also of eosinophils, B-lymphocytes, and plasma cells indicating myocarditis. Read More

    A cohort study reveals myocarditis to be a rare and life-threatening presentation of large vessel vasculitis.
    Semin Arthritis Rheum 2017 Apr 4. Epub 2017 Apr 4.
    Rheumatology Department, Imperial College Healthcare NHS Trust and Imperial College London, Hammersmith Hospital, London, UK.
    Background: The predominant forms of adult large vessel vasculitis (LVV) are giant cell arteritis (GCA) and Takayasu arteritis (TA). Cardiac involvement in LVV is a cause of morbidity and mortality, particularly in TA. Cardiac failure is most commonly secondary to uncontrolled arterial hypertension or myocardial ischaemia. Read More

    Feature-tracking myocardial strain analysis in acute myocarditis: diagnostic value and association with myocardial oedema.
    Eur Radiol 2017 May 12. Epub 2017 May 12.
    Department of Radiology, University of Bonn, Sigmund-Freud-Str. 25, 53127, Bonn, Germany.
    Objectives: To investigate the diagnostic value of cardiac magnetic resonance (CMR) feature-tracking (FT) myocardial strain analysis in patients with suspected acute myocarditis and its association with myocardial oedema.

    Methods: Forty-eight patients with suspected acute myocarditis and 35 control subjects underwent CMR. FT CMR analysis of systolic longitudinal (LS), circumferential (CS) and radial strain (RS) was performed. Read More

    Inhibition of iNOS protects cardiomyocytes against coxsackievirus B3-induced cell injury by suppressing autophagy.
    Biomed Pharmacother 2017 May 9;91:673-679. Epub 2017 May 9.
    Department of Cardiology, Tianjin Union Medical Center, Tianjin 300121, China.
    Background: Coxsackievirus B3 (CVB3), a member of the picornavirus family, is one of the major causative enteroviruses of viral myocarditis. The aim of the current study was to investigate the role and underlying mechanism of iNOS and autophagy in CVB3 infected cardiomyocytes.

    Methods: Myocardial cell H9c2 were randomly divided into four groups: control group, CVB3 group, CVB3+L-NAME group and the CVB3+iNOS siRNA group. Read More

    T2 mapping and T2* imaging in heart failure.
    Heart Fail Rev 2017 May 11. Epub 2017 May 11.
    Cardiovascular Biomedical Research Unit, Royal Brompton Hospital, National Heart and Lung Institute, Imperial College, Sydney Street, London, SW3 6NP, UK.
    Cardiovascular magnetic resonance (CMR) is a versatile imaging modality that enables aetiological assessment and provides additional information to that of standard echocardiography in a significant proportion of patients with heart failure. In addition to highly accurate and reproducible assessment of ventricular volumes and replacement fibrosis, multiparametric mapping techniques have rapidly evolved to further expand the diagnostic and prognostic applications in various conditions ranging from acute inflammatory and ischaemic cardiomyopathy, to cardiac involvement in systemic diseases such as sarcoidosis and iron overload cardiomyopathy. In this review, we discuss the established role of T2* imaging and rapidly evolving clinical applications of myocardial T2 mapping as quantitative adjuncts to established qualitative imaging techniques. Read More

    Eosinophils in Autoimmune Diseases.
    Front Immunol 2017 27;8:484. Epub 2017 Apr 27.
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
    Eosinophils are multifunctional granulocytes that contribute to initiation and modulation of inflammation. Their role in asthma and parasitic infections has long been recognized. Growing evidence now reveals a role for eosinophils in autoimmune diseases. Read More

    Atrial Septostomy for Left Atrial Decompression During Extracorporeal Membrane Oxygenation by Inoue Balloon Catheter.
    Circ J 2017 May 11. Epub 2017 May 11.
    Division of Cardiovascular Medicine, Department of Medicine, China Medical University Hospital.
    Background: Refractory pulmonary edema is an infrequent but serious complication in patients receiving venoarterial extracorporeal membrane oxygenation (VA-ECMO) for myocardial failure. Left atrial (LA) decompression in this setting is important. Although a few methods have been reported, the experience is mostly limited to children. Read More

    A Survival Case of Fulminant Right-Side Dominant Eosinophilic Myocarditis.
    Int Heart J 2017 May 12. Epub 2017 May 12.
    Department of Cardiology and Nephrology, Mie University Graduate School of Medicine.
    A 59-year-old Japanese woman was admitted to a nearby hospital with dyspnea and general malaise. Transthoracic echocardiography revealed right ventricular (RV) dilatation with severely reduced systolic function and leftward shift of the intraventricular septum. She was initially diagnosed with acute right heart failure, and fell into cardiogenic shock requiring an intra-aortic balloon pump and inotropic agents. Read More

    Neospora caninum abortion in a Malayan tapir (Tapirus indicus).
    Vet Parasitol 2017 May 15;239:37-41. Epub 2017 Apr 15.
    Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Institute of Epidemiology, Südufer 10, D-17493 Greifswald, Insel Riems, Germany.
    A captive 17-year old female Malayan tapir (Tapirus indicus) aborted a fetus with a crown rump length of 19cm in early pregnancy. The fetus showed an early state of mummification. Histologically, a multifocal mononuclear encephalitis, myocarditis and periportal hepatitis was present indicating a possible protozoal cause of abortion. Read More

    Coinfection by Streptococcus phocae and cetacean morbillivirus in a short-beaked common dolphin Delphinus delphis.
    Dis Aquat Organ 2017 May;124(3):247-252
    Veterinary Histology and Pathology, Institute of Animal Health, Veterinary College, University of Las Palmas de Gran Canaria, Trasmontana s/n, Arucas 35413, Las Palmas de Gran Canaria, Spain.
    We describe gross, histopathological, and immunohistochemical features of Streptococcus phocae and cetacean morbillivirus coinfection in a short-beaked common dolphin Delphinus delphis. Major gross findings were cutaneous purulent nodules in the tail fluke, vegetative mitral valve endocarditis, and presumed postpartum pyometra. Histologic examination revealed bacterial septicemia characterized by widespread intravascular coccoid bacterial emboli. Read More

    Speckle tracking echocardiography in acute lupus myocarditis: comparison to conventional echocardiography.
    Echo Res Pract 2017 May 10. Epub 2017 May 10.
    R du Toit, Division of Rheumatology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University and Tygerberg Academic Hospital, Cape Town, South Africa.
    Aims: Lupus myocarditis occurs in 5-10% of patients with systemic lupus erythematosus (SLE). No single feature is diagnostic of lupus myocarditis. Speckle tracking echocardiography (STE) can detect sub-clinical left ventricular dysfunction in SLE patients, with limited research on its utility in clinical lupus myocarditis. Read More

    Clinical characteristics and outcomes of patients with myocarditis mimicking ST-segment elevation myocardial infarction: Analysis of a case series.
    Medicine (Baltimore) 2017 May;96(19):e6863
    Emergency and Intensive Care Center, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China.
    Acute myocarditis mimicking ST-segment elevation myocardial infarction (STEMI) is highly deceptive for an accurate diagnosis, and a systematic study is lacking with regard to the clinical features and prognosis of this distinct clinical entity.Patients with suspected STEMI and eventually diagnosed with myocarditis by cardiac magnetic resonance (CMR) from January 2012 to April 2016 at Fuwai Hospital were identified by reviewing medical records and electronic databases. Follow-up was conducted by clinical visits and phone contacts in a median duration of 17 months. Read More

    Reversible Myocardial Injury and Intraventricular Thrombus Associated with Aluminium Phosphide Poisoning.
    Case Rep Cardiol 2017 9;2017:6287015. Epub 2017 Apr 9.
    Department of Cardiology B, Ibn Sina Hospital, Mohammed V University, Rabat, Morocco.
    Aluminium phosphide (ALP) is widely used as a fumigant pesticide. In case of ALP poisoning, it is responsible for myocardial dysfunction, related to toxic myocarditis, and hemodynamic disorders. We report a case of a 28-year-old female who had intentionally ingested ALP and was admitted with cardiogenic shock. Read More

    Complete heart block complicating the acute phase of respiratory syncytial virus bronchiolitis.
    Pediatr Pulmonol 2017 May 9. Epub 2017 May 9.
    Department of Paediatric Cardiology and Adult with Congenital Heart Disease, Onassis Cardiac Surgery Center, Athens, Greece.
    Respiratory syncytial virus is the most common pathogen causing lower respiratory tract infection in infants. In recent years, the importance of extrapulmonary complications and longterm sequelae including those involving the cardiovascular system has become apparent. We report on a 10 month old infant with respiratory syncytial virus bronchiolitis, the acute phase of which was complicated by irreversible complete heart block, which was managed conservatively. Read More

    Lipoxin A4 mitigates experimental autoimmune myocarditis by regulating inflammatory response, NF-κB and PI3K/Akt signaling pathway in mice.
    Eur Rev Med Pharmacol Sci 2017 Apr;21(8):1850-1859
    Department of Cardiology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong, China.
    Objective: Myocarditis, an acute inflammation disease of the heart, is a potentially lethal disease and can lead to sudden death. This study aims to investigate the therapeutic effect of lipoxin A4 (LXA4) on experimental autoimmune myocarditis (EAM) and to explore the underlying mechanism.

    Materials And Methods: EAM was induced in BALB/c mice by injection of porcine cardiac myosin and LAX4 at doses of 10 or 50 μg/kg was administrated from day 1 to 21. Read More

    Increased expression of CXCR5 and CXCL13 in mice with experimental autoimmune myocarditis.
    Eur Rev Med Pharmacol Sci 2017 Apr;21(8):1860-1867
    Department of Anesthesiology, China-Japan Union Hospital of Jilin University, Changchun, Jilin, China.
    Objective: Myocarditis is an inflammatory heart muscle disease associated with cardiac dysfunction, and autoimmunity is considered to play an important role in the pathogenesis of myocarditis. CXCL13 and its receptor CXCR5 have been reported to be associated with many diseases including some cancers and inflammatory diseases, but so far there has been no report on CXCR5/CXCL13 expression in myocarditis.

    Materials And Methods: With a mouse experimental autoimmune myocarditis (EAM) model, it was found that the mRNA and protein expression of both CXCR5 and CXCL13 were increased in myocardial tissue in the EAM mice. Read More

    The protective effects of taurine on experimental autoimmune myocarditis.
    Eur Rev Med Pharmacol Sci 2017 Apr;21(8):1868-1875
    Department of Clinical Laboratory, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong, China.
    Objective: To investigate the protective effects of taurine on experimental autoimmune myocarditis and its mechanisms. BALB/c mice were immunized with porcine cardiac myosin to induce experimental autoimmune myocarditis (EAM).

    Materials And Methods: We administered taurine (5 mg/kg, 10 mg/kg or 20 mg/kg) or vehicle to EAM mice daily. Read More

    Clinical spectrum and therapeutic management of systemic lupus erythematosus-associated macrophage activation syndrome: A study of 103 episodes in 89 adult patients.
    Autoimmun Rev 2017 May 5. Epub 2017 May 5.
    Service d'immunologie Clinique et médecine interne, CHU de Strasbourg.
    Objectives: Macrophage activation syndrome (MAS) is a life-threatening hyperinflammatory syndrome that can occur during systemic lupus erythematosus (SLE). Data on MAS in adult SLE patients are very limited. The aim of this study is to describe the clinical characteristics, laboratory findings, treatments, and outcomes of a large series of SLE-associated MAS. Read More

    Dramatic and early response to low-dose steroid in the treatment of acute eosinophilic myocarditis: a case report.
    BMC Cardiovasc Disord 2017 May 8;17(1):115. Epub 2017 May 8.
    Division of Interventional Cardiology, Cardiovascular Center, Taichung Veterans General Hospital, 1650 Taiwan Boulevard Sect. 4, Taichung, 40705, Taiwan, Republic of China.
    Background: Eosinophilic myocarditis encompasses a variety of etiologies and the prognosis varies. For patients with a hypersensitive response to medications, high-dose corticosteroids and discontinuation of culprit medications are the main treatments.

    Case Presentation: We reported a young man with biopsy-proven eosinophilic myocarditis which was possibly induced by Chinese herbal medicine. Read More

    Complete Freund's adjuvant induces experimental autoimmune myocarditis by enhancing IL-6 production during initiation of the immune response.
    Immun Inflamm Dis 2017 Jun 13;5(2):163-176. Epub 2017 Mar 13.
    W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.
    Introduction: Complete Freund's Adjuvant (CFA) emulsified with an antigen is a widely used method to induce autoimmune disease in animal models, yet the contribution of CFA to the immune response is not well understood. We compared the effectiveness of CFA with Incomplete Freund's Adjuvant (IFA) or TiterMax Gold Adjuvant (TMax) in experimental autoimmune myocarditis (EAM) in male mice.

    Methods: EAM was induced in A/J, BALB/c, and IL6KO BALB/c male mice by injection of the myocarditogenic peptide in CFA, IFA, or TMax on days 0 and 7. Read More

    Short-term mechanical circulatory support as a bridge to durable left ventricular assist device implantation in refractory cardiogenic shock: a systematic review and meta-analysis.
    Eur J Cardiothorac Surg 2017 May 3. Epub 2017 May 3.
    Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, Netherlands.
    Summary: Short-term mechanical circulatory support (MCS) is increasingly used as a bridge to decision in patients with refractory cardiogenic shock. Subsequently, these patients might be bridged to durable MCS either as a bridge to candidacy/transplantation, or as destination therapy. The aim of this study was to review support duration and clinical outcome of short-term MCS in cardiogenic shock, and to analyse application of this technology as a bridge to long-term cardiac support (left ventricular assist device, LVAD) from 2006 till June 2016. Read More

    Increased risk of ventricular tachycardia and cardiovascular death in patients with myocarditis during the long-term follow-up: A national representative cohort from the National Health Insurance Research Database.
    Medicine (Baltimore) 2017 May;96(18):e6633
    aDivision of Cardiology, Department of Medicine, Taipei Veterans General Hospital bSchool of Medicine, Institute of Clinical Medicine and Cardiovascular Research Center, National Yang-Ming University cInstitute of Epidemiology and Preventive Medicine College of Public Health, National Taiwan University, Taipei, Taiwan.
    The incidence of acute myocarditis complicated with ventricular tachycardia (VT) is unknown. This study aimed to investigate the association between myocarditis and the incidence of VT and mortality. We also aimed to determine the independent predictors that increased the VT risk in those patients. Read More

    Centers for Medicare and Medicaid Services' readmission reports inaccurately describe an institution's decompensated heart failure admissions.
    Clin Cardiol 2017 May 4. Epub 2017 May 4.
    Division of Cardiology, Vanderbilt University Medical Center, Nashville, Tennesee.
    Hospitals typically use Center for Medicare and Medicaid Services' (CMS) Hospital Readmission Reduction Program (HRRP) administrative reports as the standard of heart failure (HF) admission quantification. We aimed to evaluate the HF admission population identified by CMS HRRP definition of HF hospital admissions compared with a clinically based HF definition. We evaluated all hospital admissions at an academic medical center over 16 months in patients with Medicare fee-for service benefits and age ≥65 years. Read More

    Clinical imaging in patients experiencing chest pain.
    Minerva Cardioangiol 2017 May 3. Epub 2017 May 3.
    Department of Cardiology, University Hospital "San Giovanni di Dio e Ruggi d'Aragona", Salerno, Italy -
    Non-invasive imaging modalities integrate the clinical and laboratory diagnostic work-up of patients admitted in emergency department for chest pain. Transthoracic echocardiography is the first-line imaging tool because it is rapidly and widely available, bedside feasible and cost-effective. Even when a comprensive exam is not feasible, a fast focused ultrasound exam should be performed. Read More

    An alternative technique to safely close the chest after placing a child on central venoarterial extracorporeal membrane oxygenation.
    Clin Case Rep 2017 May 29;5(5):729-730. Epub 2017 Mar 29.
    Department of Pediatric and Congenital Heart SurgeryOnassis Cardiac Surgery CenterAthensGreece.
    Central venoarterial (VA) placement of extracorporeal membrane oxygenation (ECMO) is performed surgically, and in the majority of cases, the patient remains with an open sternum. Herein, a case of a 3-year-old patient who underwent insertion of a central VA ECMO for heart failure due to acute myocarditis is described. An alternative technique for ECMO placement providing sternal closure and minimizing infection risk for the safe patient transport is described. Read More

    Myopericarditis in a patient with hepatitis C and cryoglobulinemic renal disease.
    Clin Case Rep 2017 May 21;5(5):616-620. Epub 2017 Mar 21.
    Division of NephrologyHennepin County Medical CenterMinneapolisMinnesotaUSA.
    Although cryoglobulinemia is a well-appreciated complication of hepatitis C (HC), myopericarditis with resulting pericardial effusion is extremely rare, especially in the absence of a liver transplant. In patients with HC, pericardial effusion with impending tamponade can be a florid and potentially life-threatening manifestation of multiorgan cryoglobulinemic disease. Read More

    Adult murine cardiomyocytes exhibit regenerative activity with cell cycle reentry through STAT3 in the healing process of myocarditis.
    Sci Rep 2017 May 3;7(1):1407. Epub 2017 May 3.
    Laboratory of Clinical Science and Biomedicine, Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka, 565-0871, Japan.
    Mammalian cardiomyocytes substantially lose proliferative capacity immediately after birth, limiting adult heart regeneration after injury. However, clinical myocarditis appears to be self-limiting with tissue-reparative properties. Here, we investigated the molecular mechanisms underlying the recovery from myocarditis with regard to cardiomyocyte proliferation using an experimental autoimmune myocarditis (EAM) model. Read More

    [Health related quality of life on severe hand, foot and mouth disease patients].
    Zhonghua Liu Xing Bing Xue Za Zhi 2017 Apr;38(4):462-466
    Division of Infectious Disease, Key Laboratory of Surveillance and Early Warning on Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
    Objective: To evaluate the health related quality of life (HRQoL) for severe hand, foot and mouth disease (HFMD) patients with different complications. Methods: A national telephone interview under the EQ-5D proxy2 questionnaire (EQ-SD and EQ-VAS), was conducted to obtain the HRQoL of lab-confirmed severe HFMD patients, aged between six months and five-year-olds from the national communicable disease surveillance system from January 1, 2012 to December 31, 2013. Results: A total of 685 severe HFMD cases were included in the study. Read More

    [Cardiac support and replacement systems].
    Med Klin Intensivmed Notfmed 2017 May 2. Epub 2017 May 2.
    Universitäres Herzzentrum Lübeck Medizinische Klinik II (Kardiologie, Angiologie, Intensivmedizin), Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Deutschland.
    In recent years, the widespread use of partial mechanical cardiac support and even temporary complete replacement of cardiac function has been established in many intensive care units in the treatment of refractory cardiogenic shock. There is a difference between partial left-ventricular assist devices (LVAD) and the possibility of complete heart (and lung) replacement by extra corporeal life support (ECLS). Despite the use of mechanical support devices, the mortality of cardiogenic shock remains high. Read More

    Safety and efficacy of epicardial approach to catheter ablation of ventricular tachycardia - An institutional experience.
    Indian Heart J 2017 Mar - Apr;69(2):170-175. Epub 2016 Nov 5.
    CARE Hospital, Road No.1, Banjara Hills, Hyderabad 500 034, India. Electronic address:
    Background And Aim: Epicardial approach to VT ablation increases the success rate of ablation but is not without complications. We studied the safety and efficacy of epicardial VT ablations performed at our institute.

    Methods: All patients who underwent epicardial VT ablation at our institute were studied retrospectively. Read More

    Myocarditis, flail tricuspid valve, and normal rhythm: an exceptional form of neonatal cardiac lupus.
    Cardiol Young 2017 May 2:1-4. Epub 2017 May 2.
    1Pediatric Cardiac Surgery Department,Gregorio Marañón Hospital,Madrid,Spain.
    Neonatal cardiac lupus is a rare, passively acquired autoimmune disease. We report a case of in utero myocarditis, confirmed postnatally, with papillary muscle rupture and severe tricuspid regurgitation after birth in the absence of conduction disturbances. Tricuspid repair was successfully performed with polytetrafluoroethylene neochordae. Read More

    Clinical Features and Neurologic Complications of Children Hospitalized With Chikungunya Virus in Honduras.
    J Child Neurol 2017 Jan 1:883073817701879. Epub 2017 Jan 1.
    4 National Autonomous University of Honduras Hospital Escuela, Tegucigalpa, Honduras.
    The first case of Chikungunya virus in Honduras was identified in 2014. The virus has spread widely across Honduras via the Aedes aegypti mosquito, leading to an outbreak of Chikungunya virus (CHIKV) in 2015 that significantly impacted children. A retrospective chart review of 235 children diagnosed with CHIKV and admitted to the National Autonomous University of Honduras Hospital Escuela (Hospital Escuela) in Tegucigalpa, Honduras, was accomplished with patients who were assessed for clinical features and neurologic complications. Read More

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