19,077 results match your criteria Myocarditis


Combined checkpoint inhibitor-associated myocarditis and pulmonary vasculitis mimicking acute pulmonary embolism.

Eur Heart J Cardiovasc Imaging 2018 Dec 11. Epub 2018 Dec 11.

Cardio-Thoracic-Vascular Department, San Raffaele Hospital, Via Olgettina 60, Milan 20132, Italy.

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December 2018

Marijuana Induced Myocarditis: A New Entity of Toxic Myocarditis.

Am J Med Case Rep 2018 26;6(9):169-172. Epub 2018 Sep 26.

Department of Internal Medicine, State University of New York Downstate Medical Center, Brooklyn, New York, U.S.A- 11203.

Marijuana is the most common drug of abuse in the United States. Marijuana has more than 460 active chemical compounds including δ-9- tetrahydrocannabinol (THC). It acts via the CB1 and CB2 receptors that are distributed in various tissues in the body. Read More

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September 2018

Clinical and Laboratory Characteristics of an Acute Chikungunya Outbreak in Bangladesh in 2017.

Am J Trop Med Hyg 2018 Dec 10. Epub 2018 Dec 10.

Department of Internal Medicine, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.

From April to September 2017, Bangladesh experienced a huge outbreak of acute Chikungunya virus infection in Dhaka. This series describes the clinical and laboratory features of a large number of cases (690; 399 confirmed and 291 probable) suffered during that period. This observational study was carried out at Dhaka Medical College Hospital, Bangladesh. Read More

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December 2018

Inflammatory and Infectious Syndromes Associated with Cancer Immunotherapies.

Clin Infect Dis 2018 Dec 6. Epub 2018 Dec 6.

Department of Medicine, Harvard Medical School, Boston, MA, USA.

Immunotherapy using antibodies to immune checkpoint molecules or targeted chimeric antigen receptor-modified T (CAR-T) cells represent dramatic advances in cancer treatment. These therapies mediate immune-related adverse events (irAEs) which may mimic or amplify infectious presentations. Checkpoint inhibitor therapy may be associated with diverse irAEs including mild skin, endocrine and autoimmune manifestations or severe inflammatory processes including colitis, pneumonitis, myocarditis, and shock. Read More

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December 2018
2 Reads

Chinese society of cardiology expert consensus statement on the diagnosis and treatment of adult fulminant myocarditis.

Sci China Life Sci 2018 Dec 3. Epub 2018 Dec 3.

Department of Cardiology, Changzheng Hospital, The Second Military Medical University, Shanghai, 200003, China.

Fulminant myocarditis is primarily caused by infection with any number of a variety of viruses. It arises quickly, progresses rapidly, and may lead to severe heart failure or circulatory failure presenting as rapid-onset hypotension and cardiogenic shock, with mortality rates as high as 50%-70%. Most importantly, there are no treatment options, guidelines or an expert consensus statement. Read More

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December 2018
2 Reads

Fecal microbiota transplantation alleviates myocardial damage in myocarditis by restoring the microbiota composition.

Pharmacol Res 2018 Nov 30;139:412-421. Epub 2018 Nov 30.

Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, China. Electronic address:

Myocarditis can be caused by several infectious and noninfectious causes. Treatment for myocarditis is still a difficult task in clinical practice. The gut microbiota is related to cardiovascular diseases such as atherosclerosis and hypertension. Read More

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November 2018

Beyond thrombocytopaenia, haemorrhage and shock: the expanded dengue syndrome.

Pathog Glob Health 2018 Dec 3:1-11. Epub 2018 Dec 3.

c Department of Parasitology, Faculty of medicine , University of Colombo , Colombo , Sri Lanka.

Dengue infection classically presents with fever, thrombocytopaenia, and varying degrees of plasma leakage, giving rise to shock. However, a myriad of other manifestations, involving the cardiovascular system, the nervous system, the liver, the kidneys, the gut and the haematological system have been reported in dengue. This review summarizes these varied presentations. Read More

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December 2018
3 Reads

Leptospirosis presenting as severe cardiogenic shock: A case report.

J Intensive Care Soc 2018 Nov 29;19(4):351-353. Epub 2018 Jan 29.

Adult Intensive Care Unit, Royal Brompton Hospital, London, UK.

Background: Leptospirosis is a rare infectious illness caused by the Spirochaete Leptospira. It has a wide-varying spectrum of presentation. We present a rare case of severe cardiogenic shock secondary to leptospirosis, in the absence of its common clinical features. Read More

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November 2018
1 Read

[Multicenter investigation of extracorporeal membrane oxygenation application in pediatric intensive care unit in China].

Zhonghua Er Ke Za Zhi 2018 Dec;56(12):929-932

Department of Pediatric Emergency Medicine, Children's Hospital of Fudan University, Shanghai 201102, China.

To survey the conduction and evaluate the effectiveness of extracorporeal membrane oxygenation (ECMO) therapy in pediatric intensive care unit (PICU) in China mainland. In a questionnaire-based survey, we retrospectively reviewed the application of ECMO in children's hospital and general hospital in China mainland to summarize and analyze the categories of diseases and prognosis of children treated with ECMO therapy. By December 31, 2017, a total of 23 hospitals using ECMO, including 22 tertiary referral hospitals and 1 secondary hospital, among which 16 were children's hospitals and 7 were general hospitals. Read More

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December 2018
3 Reads

Type 1 cardiorenal syndrome in a patient with an acute infection caused by Trypanosoma cruzi in the Brazilian Amazon region - a case report.

Rev Soc Bras Med Trop 2018 Nov-Dec;51(6):869-872

Programa de Pós-Graduação em Medicina Tropical, Universidade do Estado do Amazonas, Manaus, AM, Brasil.

Cardiorenal syndrome type 1 (CRS 1) occurs when acute heart failure leads to acute kidney injury. There are several etiologies of CRS 1, including Chagas disease. Here, we present the first case report of CRS 1 in a patient with acute Chagas disease. Read More

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April 2018
2 Reads

Acute fulminant myocarditis in a patient with primary Sjögren's syndrome.

Scand J Rheumatol 2018 Dec 5:1-2. Epub 2018 Dec 5.

b Department of Cardiology , Tomakomai City Hospital , Tomakomai , Japan.

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December 2018
1 Read

Clozapine-induced myocarditis in Canada: Evidence from spontaneous reports.

Schizophr Res 2018 Dec 1. Epub 2018 Dec 1.

Schizophrenia Division, Centre for Addiction and Mental Health, Toronto, ON, Canada; Department of Psychiatry, University of Toronto, Toronto, ON, Canada. Electronic address:

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December 2018
1 Read

Intravenous zanamivir for influenza myocarditis and enteral malabsorption.

Crit Care 2018 Dec 4;22(1):332. Epub 2018 Dec 4.

Department of Intensive Care Medicine and Burns, Lausanne University Hospital Medical Center, CHUV, 1011, Lausanne, Switzerland.

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December 2018

Neonatal acute liver failure due to enteroviruses: a 14 years single NICU experience.

J Matern Fetal Neonatal Med 2018 Dec 4:1-171. Epub 2018 Dec 4.

a Department of Neonatology , Bambino Gesù Children's Hospital - IRCCS , Rome , Italy.

Background: Neonatal acute liver failure (ALF) is a severe condition with a mortality rate up to 70%. Human enterovirus (HEV) infections are associated with serious diseases in newborns, including myocarditis, meningoencephalitis and, more rarely, ALF with a fulminant course.

Methods: Cases of neonatal-onset ALF were identified using the institutional clinical database. Read More

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December 2018
2 Reads

An Out-of-Season Case of Coxsackie B Myocarditis with Severe Rhabdomyolysis.

Case Rep Infect Dis 2018 30;2018:4258296. Epub 2018 Oct 30.

Internal Medicine Residency Program, Mount Sinai Hospital, Chicago, IL, USA.

A 21-year-old woman was found to have fulminant myocarditis as a result of Coxsackie B infection (a virus shown to exhibit summer-fall seasonality) in mid-December. In this case report, seasonality of enteroviruses is examined, as well as additional factors which may contribute to sporadic cases during winter months. The case report also discusses clinical criteria for endomyocardial biopsy, utility of PCR vs. Read More

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October 2018

causing myocarditis in a previously healthy 22-year-old male.

Oxf Med Case Reports 2018 Dec 26;2018(12):omy106. Epub 2018 Nov 26.

Department of Medicine and Geriatrics, Höglandssjukhuset, Eksjö, Sweden.

Myocarditis is mostly caused by viral infections and rarely caused by bacterial pathogens, especially in immunocompetent individuals. Bacterial myocarditis due to is rare, especially in countries with improved sanitation that minimize contamination of serotypes. We here present a case of a previous healthy 22-year-old male that came to the emergency room with chest pain. Read More

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December 2018
2 Reads

Mortality, Resource Utilization And Inpatient Costs Vary Among Pediatric Heart Transplant Indications: A Merged Data Set Analysis From The United Network For Organ Sharing And The Pediatric Health Information Systems (UNOS-PHIS) Databases.

J Card Fail 2018 Nov 25. Epub 2018 Nov 25.

Division of Pediatric Oncology, The Children's Hospital of Philadelphia; Philadelphia, PA.

Background: Merging UNOS and PHIS databases have enabled a more granular analysis of pediatric heart transplant outcomes and resource utilization. We evaluated whether transplant indication at time of transplantation was associated with mortality, resource utilization and inpatient costs during the first year post-transplant.

Methods: We analyzed transplant outcomes and resource utilization between 2004 and 2015. Read More

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November 2018

miR-203 accelerates apoptosis and inflammation induced by LPS via targeting NFIL3 in cardiomyocytes.

J Cell Biochem 2018 Nov 28. Epub 2018 Nov 28.

Department of Cardiology, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, China.

Myocarditis is an inflammatory disease of the myocardium. MicroRNA-203 (miR-203) is involved in various physiological and pathological processes. In this work, we aimed to explore the roles and potential mechanisms of miR-203 in myocarditis in vitro. Read More

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November 2018

Transfemoral aortic valve replacement for severe aortic valve regurgitation in a patient with a pulsatile-flow biventricular assist device.

ESC Heart Fail 2018 Nov 27. Epub 2018 Nov 27.

Department of Internal Medicine III, Cardiology, Angiology and Pneumology, University of Heidelberg, Heidelberg, Germany.

Severe aortic regurgitation (AR) is a rare but significant complication of ventricular assist device therapy. Experience with transcatheter aortic valve replacement (TAVR) in this setting of patients is very limited, while the scarcely reported cases exclusively refer to TAVR under continuous-flow left ventricular assist devices. Here, we present the first successful TAVR while running a pulsatile-flow biventricular assist device (PF-BiVAD). Read More

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November 2018
1 Read

An upstream protein-coding region in enteroviruses modulates virus infection in gut epithelial cells.

Nat Microbiol 2018 Nov 26. Epub 2018 Nov 26.

Division of Virology, Department of Pathology, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.

Enteroviruses comprise a large group of mammalian pathogens that includes poliovirus. Pathology in humans ranges from sub-clinical to acute flaccid paralysis, myocarditis and meningitis. Until now, all of the enteroviral proteins were thought to derive from the proteolytic processing of a polyprotein encoded in a single open reading frame. Read More

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November 2018
3 Reads

Electrocardiographic changes after implantation of a left ventricular assist device - Potential implications for subcutaneous defibrillator therapy.

J Electrocardiol 2018 Nov 2;52:29-34. Epub 2018 Nov 2.

Rhythmology and Electrophysiology, Department of Cardiology and Angiology, Hannover Medical School, Hannover, Germany. Electronic address:

Background: Implantation of a left ventricular assist device (LVAD) leads to a diverse spectrum of changes on the twelve-lead surface electrocardiogram (ECG). We aimed to elucidate the changes of the surface ECG in patients after LVAD implantation potentially impacting ECG based screening tests of subcutaneous implantable cardioverter-defibrillators (S-ICD).

Methods: Patients from 2005 until 2017 with a documented twelve-lead ECG before and after LVAD implantation were included. Read More

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November 2018
3 Reads

Arrhythmias in Myocarditis: State of the Art.

Heart Rhythm 2018 Nov 23. Epub 2018 Nov 23.

Department of Cardiac Electrophysiology and Arrhythmology, IRCCS San Raffaele Hospital, Milan, Italy.

Many kinds of arrhythmias may occur in patients with myocarditis at any stage of the disease. However, as compared to the other clinical presentations, arrhythmic myocarditis has been poorly described so far in the literature. In fact, arrhythmias occurring in either ongoing or previous myocardial inflammation are complex and heterogeneous, and the disease itself is often underdiagnosed, thus limiting data collection and interpretation. Read More

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November 2018
6 Reads

Importance of endomyocardial biopsy in distinguishing between cardiac sarcoidosis and giant cell myocarditis : Need to distinguish between sarcoidosis and giant cell myocarditis.

Wien Klin Wochenschr 2018 Nov 23. Epub 2018 Nov 23.

2nd Department of Medicine, Department of Cardiovascular Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, U Nemocnice 2, 12808, Prague, Czech Republic.

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November 2018
1 Read

Beta-adrenergic receptor antibodies in children with dilated cardiomyopathy.

Front Biosci (Elite Ed) 2019 01 1;11:102-108. Epub 2019 Jan 1.

Pediatric Nephrologist . Hospital Universitario Gregorio Marañon. Madrid, Spain.

Autoantibodies to beta-1 adrenergic receptor have been reported in adult patients with dilated cardiomyopathy (DCM). Removal of these antibodies has a positive hemodynamic effect. Our aim was to investigate whether these antibodies are present in children with DCM and explore the potential hemodynamic benefit of immunoadsorption (IA). Read More

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January 2019
2 Reads

Clozapine-related Sudden Pericarditis in a Patient Taking Long Acting Aripiprazole and Valproate: A Case Report.

Clin Psychopharmacol Neurosci 2018 Nov;16(4):505-507

Department of Neurosciences and Imaging, University "G. d'Annunzio", Chieti, Italy.

Clozapine may be associated with cardiovascular adverse effects including QTc prolongation and, more rarely, with myocarditis and pericarditis. Although rare, these latter cardiovascular adverse effects may be life-threatening and must be immediately recognized and treated. Several cases of clozapine related-pericarditis have been described and often it has a subtle and insidious onset with symptoms that may be often misdiagnosed with psychiatric manifestations (e. Read More

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November 2018
3 Reads

Forensic Analysis on 52 Medical Malpractice Cases of Cardiac Death.

Authors:
J Lu Y L Zhang L Luo

Fa Yi Xue Za Zhi 2018 Aug 25;34(4):389-391. Epub 2018 Aug 25.

Xiaoshan Branch Office, Hangzhou Minghao Forensic Judical Appraisal Institute, Hangzhou 311200, China.

Objectives: To synthetically analyse the medical malpractice cases of cardiac death in forensic identification, and to explore the generality and characteristic of cause of death, medical malpractice and assessment of participation degree.

Methods: Totally 52 medical malpractice cases of cardiac death examined in the Xiaoshan Branch Office, Hangzhou Minghao Forensic Judical Appraisal Institute, from January 2015 to April 2018 were collected. The general information of cases, medical institutions and situations of hospital stay, cause of death, medical malpractice and assessment of participation degree were retrospectively analysed. Read More

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August 2018
8 Reads

Associations with the In-Hospital Survival Following Extracorporeal Membrane Oxygenation in Adult Acute Fulminant Myocarditis.

J Clin Med 2018 Nov 20;7(11). Epub 2018 Nov 20.

Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.

Background: Acute fulminant myocarditis (AFM) is a serious disease that progresses rapidly, and leads to failing respiratory and circulatory systems. When medications fail to reverse the patient's clinical course, extracorporeal membrane oxygenation (ECMO) is considered the most effective, supportive and adjunct strategy. In this paper we analyzed our experience in managing AFM with ECMO support. Read More

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November 2018
4 Reads

Cardiovascular magnetic resonance can be undertaken in pregnancy and guide clinical decision-making in this patient population.

Eur Heart J Cardiovasc Imaging 2018 Nov 20. Epub 2018 Nov 20.

Division of Cardiology, Department of Medicine, University of Cape Town and Groote Schuur Hospital, Main Rd, Observatory, Cape Town, South Africa.

Aims: Cardiovascular disease is the leading cause of maternal morbidity and mortality, frequently requiring cardiac imaging for diagnosis, and follow-up. This need does not change pregnancy; however, many centres do not offer cardiovascular magnetic resonance (CMR) to pregnant patients. This paper explores current practice of CMR in pregnancy in four large volume centres, its safety and its impact on patient management. Read More

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November 2018
3 Reads

Vaccines for Preventing Influenza in Healthy Individuals.

Authors:
Sally Liang

Acad Emerg Med 2018 Nov 21. Epub 2018 Nov 21.

Department of Emergency Medicine, SUNY Downstate Medical Center/Kings County Hospital Center.

Influenza is an acute respiratory infection that imposes a heavy burden on society. The illness itself usually lasts a few days but the residual symptoms of cough and malaise can last for weeks. In addition, it can cause complications such as otitis media, pneumonia, secondary bacterial pneumonia, exacerbations of chronic respiratory disease, bronchiolitis, febrile seizures, Reye's syndrome, and myocarditis. Read More

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November 2018
4 Reads

Cardiac manifestations of Han Chinese patients with systemic lupus erythematosus: a retrospective study.

Ir J Med Sci 2018 Nov 20. Epub 2018 Nov 20.

The Department of Rheumatology, Shenzhen Traditional Chinese Medicine Hospital, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, No. 1, Fuhua Road, Futian District, Shenzhen, 518033, Guangdong, China.

Objective: To investigate cardiac manifestations and the risk factors in Han Chinese patients with systemic lupus erythematosus (SLE).

Methods: Seven hundred fifty SLE patients who were hospitalized at our department were recruited in the present study. The patients were divided into two groups-those with or without cardiac manifestations. Read More

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November 2018
2 Reads

Acute Dissemination With Encephalitis in the Era of Biological Therapies.

Open Forum Infect Dis 2018 Nov 17;5(11):ofy259. Epub 2018 Oct 17.

Palo Alto Medical Foundation Toxoplasma Serology Laboratory, National Reference Center for the Study and Diagnosis of Toxoplasmosis, Palo Alto, California.

We report the case of a 65-year-old patient with pseudolymphoma who developed acute toxoplasmosis following 6 cycles of rituximab and bendamustine therapy. Acute toxoplasmosis in the setting of biological response modifiers, rather than reactivation, is a unique unreported infection. The patient developed severe disease with multi-organ involvement, including retinitis, myocarditis, and myositis. Read More

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November 2018
1 Read

Omphalitis, urachocystitis and septicemia by Streptococcus dysgalactiae in a southern right whale calf Eubalaena australis, Brazil.

Dis Aquat Organ 2018 Nov;131(3):227-232

Setor de Patologia Veterinária, Faculdade de Veterinária (FAVET), Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Rio Grande do Sul (RS) 91540-000, Brazil.

Southern right whales Eubalaena australis (SRW) use the southern coast of Brazil as a wintering and calving ground. Other than anthropogenic threats, there is limited knowledge on health and disease aspects for this species. We report the gross and microscopic findings and microbiological identification of streptococcal septicemia in a SRW calf. Read More

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November 2018
1 Read

Current diagnostic strategies for dilated cardiomyopathy: a comparison of imaging techniques.

Expert Rev Cardiovasc Ther 2018 Nov 20:1-11. Epub 2018 Nov 20.

a Cardiovascular Department , Università degli Studi di Trieste , Trieste , Italy.

Introduction: Dilated cardiomyopathy (DCM) is generally thought as a final common pathway of several conditions leading to the same clinical phenotype. Multiple imaging modalities play a fundamental role in recognizing the underlying pathological substrate in DCM. Areas covered: Echocardiography represents the first reliable and easily accessible diagnostic tool, allowing the identification of associated cardiac abnormalities, such as valve disease and highlighting features associated with an adverse prognosis. Read More

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November 2018
4 Reads

Cellular fraction analysis of pericardial effusion helps the diagnosis of eosinophilic myocarditis.

Cardiol Young 2018 Nov 20:1-6. Epub 2018 Nov 20.

2Department of Pathology,National Cerebral and Cardiovascular Center,Osaka,Japan.

Eosinophilic myocarditis is rare in children, and consequently, it is difficult to diagnose eosinophilic myocarditis rapidly. We report the clinical course of acute eosinophilic myocarditis with pericarditis in two adolescent boys and their associated electrocardiograms. The two patients, 13- and 14-year-old boys, developed cardiomegaly and chest pain with vomiting. Read More

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November 2018
4 Reads

Myositis and neuromuscular side-effects induced by immune checkpoint inhibitors.

Eur J Cancer 2018 Nov 16;106:12-23. Epub 2018 Nov 16.

Department of Dermatology, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Germany. Electronic address:

Aim: To characterise clinical presentation, laboratory and histopathologic characteristics and assess the treatment and outcome of neuromuscular side-effects of checkpoint therapy.

Methods: The side-effect registry and the institutional database from ten skin cancer centres were queried for reports on myositis and neuromuscular side-effects induced by checkpoint inhibitors. In total, 38 patients treated with ipilimumab, tremelimumab, nivolumab and pembrolizumab for metastatic skin cancer were evaluated and characterised. Read More

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November 2018
7 Reads

Prevalence and prognosis of ischaemic and non-ischaemic myocardial fibrosis in older adults.

Eur Heart J 2018 Nov 16. Epub 2018 Nov 16.

Department of Health and Human Services, National Heart, Lung, and Blood Institute, National Institutes of Health, Building 10, Room B1D416, MSC 1061, 10 Center Dr., Bethesda, MD, USA.

Aims: Non-ischaemic cardiomyopathies (NICM) can cause heart failure and death. Cardiac magnetic resonance (CMR) detects myocardial scar/fibrosis associated with myocardial infarction (MI) and NICM with late gadolinium enhancement (LGE). The aim of this study was to determine the prevalence and prognosis of ischaemic and non-ischaemic myocardial fibrosis in a community-based sample of older adults. Read More

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November 2018
4 Reads

Imaging the itis: endocarditis, myocarditis, and pericarditis.

Curr Opin Cardiol 2019 Jan;34(1):57-64

Division of Cardiology, Heart Transplant Program, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

Purpose Of Review: Inflammatory and/or infectious conditions affecting the heart and pericardium in children are primarily diagnosed via noninvasive imaging modalities. In addition, the use of multiple imaging modalities (multimodality imaging) is becoming increasingly common to assist in diagnosis, management, and prognosis. This review focuses on the use of noninvasive imaging in endocarditis, myocarditis, and pericarditis, with emphasis placed on the use of echocardiography and cardiac MRI in these conditions. Read More

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January 2019
1 Read

Cardiovascular toxicities associated with immune checkpoint inhibitors: an observational, retrospective, pharmacovigilance study.

Lancet Oncol 2018 Dec 12;19(12):1579-1589. Epub 2018 Nov 12.

Cardio-Oncology Program, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. Electronic address:

Background: Immune checkpoint inhibitors (ICIs) have substantially improved clinical outcomes in multiple cancer types and are increasingly being used in early disease settings and in combinations of different immunotherapies. However, ICIs can also cause severe or fatal immune-related adverse-events (irAEs). We aimed to identify and characterise cardiovascular irAEs that are significantly associated with ICIs. Read More

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December 2018
3 Reads

Myopericarditis: recognition and impact in the military population.

J R Army Med Corps 2018 Nov 14. Epub 2018 Nov 14.

Royal Army Medical Corps, Aldershot Garrison, Aldershot, UK.

We present a case of a fit and well British Army officer with sudden-onset chest pain following a viral illness, on a background of arduous skiing over an 8-week period. This resulted in a 6-month downgrade with no clearly defined plan for return to full fitness and deployability. The diagnosis and differentiation of myopericarditis from other causes of chest pain is reviewed. Read More

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November 2018
3 Reads

Porcine reproductive and respiratory syndrome virus NADC30-like strain accelerates Streptococcus suis serotype 2 infection in vivo and in vitro.

Transbound Emerg Dis 2018 Nov 14. Epub 2018 Nov 14.

Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, 250100, China.

Porcine reproductive and respiratory syndrome (PRRS), an economically significant pandemic disease, commonly results in increased impact of bacterial infections, including those by Streptococcus suis (S. suis). In recent years, PRRS virus (PRRSV) NADC30-like strain has emerged in different regions of China, and co-infected with S. Read More

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November 2018
1 Read

Characterization of rhinovirus C from a 4-year-old boy with acute onset dilated cardiomyopathy in Jakarta, Indonesia.

JMM Case Rep 2018 Sep 1;5(9):e005139. Epub 2018 Feb 1.

Cardiology Division, Department of Child Health, Faculty of Medicine Universitas Indonesia/Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia.

Introduction: Myocarditis, inflammation of the heart muscle, can be caused by infections, autoimmune disease or exposure to toxins. The major cause of myocarditis in the paediatric population is viral infection, including coxsackievirus B3, adenovirus, herpesvirus, parvovirus, influenza A and B, and hepatitis. Here, we report the detection of rhinovirus C in a boy with a clinical presentation of myocarditis, suggesting a possible causative role of this virus in this case. Read More

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September 2018
3 Reads

Heart muscle disease management in aircrew.

Heart 2019 Jan;105(Suppl 1):s50-s56

Royal Air Force Aviation Clinical Medicine Service, RAF Centre of Aviation Medicine, RAF Henlow, Bedfordshire, Oxfordshire, UK.

This manuscript focuses on the broad aviation medicine considerations that are required to optimally manage aircrew with suspected or confirmed heart muscle disease (both pilots and non-pilot aviation professionals). ECG abnormalities on aircrew periodic medical examination or presentation of a family member with a confirmed cardiomyopathy are the most common reason for investigation of heart muscle disease in aircrew. Holter monitoring and imaging, including cardiac MRI is recommended to confirm or exclude the presence of heart muscle disease and, if confirmed, management should be led by a subspecialist. Read More

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January 2019
4 Reads

Expression of tenascin C in cardiovascular lesions of Kawasaki disease.

Cardiovasc Pathol 2018 Oct 24;38:25-30. Epub 2018 Oct 24.

Department of Surgical Pathology, Toho University Ohashi Medical Center, Tokyo, Japan.

Background/objective: To examine tenascin C (TN-C) expression in coronary artery lesions (CALs) and myocardial lesions (MLs) in Kawasaki disease (KD).

Methods And Results: Twenty-five KD autopsy cases (post-KD-onset range of 6 days to 17 years) were examined in this study. Time-course analysis based on the disease day was performed of the histological findings for the CALs and MLs, as well as the localization and intensity of expression of TN-C. Read More

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October 2018
4 Reads

Call for action to establish standard diagnostic and therapeutic approaches for myocarditis.

Authors:
Naoki Sato

Int J Cardiol 2018 Nov 2. Epub 2018 Nov 2.

Cardiology and Intensive Care Unit, Nippon Medical School Musashi-Kosugi Hospital, 1-396 Kosugi-cho Nakahara-ku Kawasaki, 211-8533, Kanagawa, Japan. Electronic address:

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November 2018
3 Reads