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Ann Card Anaesth 2019 Jan-Mar;22(1):30-34

Department of Cardiothoracic Surgery, Dubai Hospital, Al Baraha, Dubai, United Arab Emeritus.

The development of a myocardial infarction ventricular septal rupture is a rare fatal complication, and the surgical repair is the treatment of choice. In most of the scenarios, the operation will be done as an emergency procedure that carries high mortality. Prognosis of these patients depends on prompt echocardiographic diagnosis and the proactive medical and surgical therapy. Read More

Ann Card Anaesth 2019 Jan-Mar;22(1):24-29

Department of Cardiology, Sri Sathya Sai Institute of Higher Medical Sciences, Bengaluru, Karnataka, India.

Background: We reviewed our experience with ruptured sinus of Valsalva aneurysms (RSOV) to determine a correlation with preexisting heart failure (HF) and coexisting cardiac lesions (aortic regurgitation [AR] and ventricular septal defect [VSD]) to postoperative left ventricular (LV) dysfunction and postoperative outcomes.

Materials And Methods: Retrospective review of RSOV cases over 15 years showed that RSOV repair was done in 87 patients. We looked for patients who presented with HF and patients having AR and/or VSDs. Read More

JAMA Netw Open 2018 Aug 3;1(4):e181281. Epub 2018 Aug 3.

Division of Cardiac Surgery, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.

Importance: The natural history of ascending aortic aneurysm (AsAA) is currently not well characterized.

Objective: To summarize and analyze existing literature on the natural history of AsAA.

Data Sources: A search of Ovid MEDLINE (January 1, 1946, to May 31, 2017) and Embase (January 1, 1974, to May 31, 2017) was conducted. Read More

Cerebrovasc Dis 2019 Jan 15;46(5-6):265-269. Epub 2019 Jan 15.

Department of Neurosurgery, Fukuoka University, Fukuoka, Japan.

Background And Purpose: Although the echogenicity of carotid plaques on carotid enhanced ultrasound (CEUS) was reported to correlate with the historological density of intra-plaque neovessels, it is unclear whether the intra-plaque vessel size is associated with carotid plaque vulnerability. We evaluated the relationship of size of intra-plaque vessels on CEUS with carotid plaque histology.

Methods: We prospectively registered patients with carotid stenosis who were hospitalized to receive carotid endarterectomy between 2012 and 2016. Read More

Am J Med Sci 2018 Nov 29. Epub 2018 Nov 29.

Department of Medicine, University of Illinois Chicago, Chicago, Illinois; Division of Hematology/Oncology, University of Illinois Chicago, Chicago, Illinois.

We present the first reported case showing metastatic giant bone cell tumor being treated successfully with pembrolizumab after failing prior tyrosine kinase inhibitor therapy. Of note, the patient developed multiple systemic effects associated with checkpoint inhibitor use. One year after starting the checkpoint inhibitor (ICI), the patient also developed hepatitis that was confirmed by liver biopsy and pathology to be, in part, due to drug-mediated toxicity similar to prior ICI toxicity cases that have been reported. Read More

J Vet Diagn Invest 2019 Jan 13:1040638718823850. Epub 2019 Jan 13.

California Animal Health & Food Safety Laboratory System, University of California-Davis, Turlock Branch, Turlock, CA.

Pasteurella multocida is the causative agent of fowl cholera, an economically important disease of commercial and backyard poultry. Turkeys are particularly susceptible to fowl cholera; both backyard and commercial turkeys can succumb to disease. On April 10, 2018, a dead 9-mo-old male Bronze turkey was submitted to the California Animal Health and Food Safety Laboratory System (CAHFS)-Turlock branch for postmortem examination. Read More

BMJ Case Rep 2019 Jan 10;12(1). Epub 2019 Jan 10.

Division of Cardiovascular Medicine, University of Missouri Health Care, Columbia, Missouri, USA.

Dobutamine stress echocardiogram (DSE) is considered a safe and reliable method for screening for underlying myocardial ischaemia. We report a case of a 60-year-old man who developed inferior ST-segment elevation myocardial infarction within 30 minutes of a normal DSE. The patient was found to have a 99% in-stent restenosis in the mid-right coronary artery with significant thrombosis for which successful percutaneous coronary intervention (PCI) was performed. Read More

Perfusion 2019 Jan 11:267659118816555. Epub 2019 Jan 11.

1 Cardio-Thoracic Surgery Department, Heart and Vascular Centre, Maastricht University Medical Centre, Maastricht, the Netherlands.

Veno-arterial extracorporeal membrane oxygenation (V-A ECMO) has been used to deal with life-threatening complications as well as back-up or active cardiovascular support during high-risk procedures in patients undergoing transcatheter aortic valve implantation (TAVI). PubMed and MEDLINE electronic databases were searched in order to identify studies with emergency or prophylactic V-A ECMO application in association with TAVI procedures. From November 2012 to November 2017, 14 relevant studies were identified that included 5,115 TAVI patients of whom 102 (2%) required V-A ECMO (22 prophylactically, 66 as an emergency and 14 without a reported indication). Read More

Cell Death Dis 2019 Jan 10;10(1):23. Epub 2019 Jan 10.

Department of Neuroscience, Center for Neurovirology, Katz School of Medicine at Temple University, Philadelphia, PA, 19140, USA.

Nuclear envelopathies are recognized genetic disorders affecting individuals with mutations in their genes encoding members of the lamin family of nuclear envelope proteins that are responsible for maintaining the architectural structure of the nucleus. Irregularity in shape and size of the nuclei, nuclear membrane rupture, and appearance of micronuclei in the cytoplasm are among the pathological features of the syndrome. Here, we demonstrate that Bcl2-associated anthanogene-3 (BAG3), a stress-induced co-chaperone protein that by association with heat-shock protein 70 (HSP70) participates in regulation of autophagy, plays a critical role in the integrity of the nuclear membrane in cardiomyocytes. Read More

J Korean Neurosurg Soc 2019 Jan 31;62(1):35-45. Epub 2018 Dec 31.

Health Insurance Review and Assessment Service, Seoul, Korea.

Objective: To describe our experiences with a fully equipped high-end digital subtraction angiography (DSA) system within a hybrid operating room (OR).

Methods: A single-plane DSA system with 3-dimensional rotational angiography, cone-beam computed tomography (CBCT), and real-time navigation software was used in our hybrid OR. Between April 2014 and January 2018, 191 sessions of cerebrovascular procedures were performed in our hybrid OR. Read More

J Cell Physiol 2019 Jan 8. Epub 2019 Jan 8.

Department of Cardiology, Beijing Key Laboratory of Early Prediction and Intervention of Acute Myocardial Infarction, Center for Cardiovascular Translational Research, Peking University People's Hospital, Beijing, China.

Background/aims: Evidence has shown that several microRNAs (miRNAs) may be involved in coronary plaque rupture and local thrombus. However, the diagnostic ability of these miRNAs in acute myocardial infarction (AMI) is less known. The aim of this study is to explore the diagnostic value of these circulating miRNAs in patients presenting with acute chest pain in the emergency department. Read More

JACC Basic Transl Sci 2018 Dec 31;3(6):719-727. Epub 2018 Dec 31.

Department of Medicine, Karolinska Institutet, Stockholm, Sweden.

An abdominal aortic aneurysm (AAA) is a progressive aortic dilation that may lead to rupture, which is usually lethal. This study identifies the state of failure in the resolution of inflammation by means of decreased expression of the pro-resolving receptor A lipoxin/formyl peptide receptor 2 (ALX/FPR2) in the adventitia of human AAA lesions. Mimicking this condition by genetic deletion of the murine ALX/FPR2 ortholog in hyperlipidemic mice exacerbated the aortic dilation induced by angiotensin II infusion, associated with decreased vascular collagen and increased inflammation. Read More

J Saudi Heart Assoc 2019 Apr 5;31(2):75-77. Epub 2018 Nov 5.

Department of Cardiovascular and Thoracic Surgery, Grant Government Medical College and Sir Jamshedjee Jeejebhoy Group of Hospitals, Mumbai 400008, India India.

Rupture of an abdominal aortic aneurysm is readily diagnosed when the triad of abdominal or back pain, shock and a pulsatile abdominal mass are present. However in a few cases, a chronic contained ruptured abdominal aortic aneurysm can present in a multitude of manners rather than as life threatening haemorrhage. In our case we are reporting a 41 year old hypertensive female who developed claudication pain in both her lower limbs. Read More

Curr Drug Discov Technol 2018 Dec 31. Epub 2018 Dec 31.

Department of Neurochemistry, Division of Basic and Applied Neurobiology, Serbsky Federal Medical Research Center of Psychiatry and Narcology, 119991 Moscow. Russian Federation.

Atherosclerosis is a chronic arterial disease characterized by vascular inflammation, accumulation of lipids in the arterial wall, and formation and growth of atherosclerotic plaques followed by ischemia. In subclinical atherosclerosis, cholesterol retention in subendothelial cells leads to induction of local inflammation, generation of foam cells and lesion formation, followed by a chain of other pathogenic events. Atherosclerotic progression can frequently be fatal, since plaque rupture may lead to thrombosis and acute events, such as myocardial infarction, stroke and sudden death. Read More

J Clin Ultrasound 2019 Jan 4. Epub 2019 Jan 4.

Department of Cardiovascular Ultrasound, The First Hospital of China Medical University, Shenyang, Liaoning, China.

Right ventricular (RV) wall dissection following ventricular septal rupture related to inferior myocardial infarction (MI) is an extremely rare complication with a high mortality rate. We report the case of a 61-year-old man who was admitted to our hospital because of syncope and intermittent chest pain with a precordial murmur. Transthoracic echocardiography showed a rupture at the basal infero-posterior septum and RV free-wall dissection forming an echolucent cavity that extended beyond the septum and subsequently re-entered into RV chamber. Read More

Nan Fang Yi Ke Da Xue Xue Bao 2018 Dec;38(12):1514-1520

College of Forensic Medicine, Southern Medical University, Guangzhou 510515, China.

Objective: To analyze the morphological features and forensic pathological characteristics of cardiac ruptures of different causes for their differential diagnosis.

Methods: We analyzed the data of 44 autopsy cases of cardiac rupture from 2014 to 2017 in our institute, including 11 cases caused by blunt violence with intact pericardium, 4 caused by cardiopulmonary resuscitation (CPR), 9 by myocardial infarction, and 20 by aorta dissection rupture.The gross features and histopathological characteristics of cardiac rupture and pericardial effusion were analyzed and compared. Read More

J Vasc Surg 2019 Jan 3. Epub 2019 Jan 3.

W. L. Gore & Associates, Inc, TAMBE Team, Flagstaff, Ariz.

Objective: This study reports the technical aspects and 30-day outcomes of the prospective, multicenter early feasibility study designed to evaluate the GORE EXCLUDER Thoracoabdominal Branch Endoprosthesis (TAMBE; W. L. Gore & Associates, Flagstaff, Ariz). Read More

Heart Vessels 2019 Jan 4. Epub 2019 Jan 4.

Department of Cardiovascular Medicine, Toho University Faculty of Medicine, 6-11-1 Omorinishi, Ota-ku, Tokyo, 143-8541, Japan.

Irregular protrusion on optical coherence tomography (OCT) is associated with clinical events and target lesion revascularization. We investigated clinical and procedure characteristics, plaque characteristics, slow flow after stent implantation, and clinical outcomes with irregular protrusion using OCT. Eighty-four lesions in 76 patients undergoing OCT before percutaneous coronary intervention were evaluated. Read More

Postepy Kardiol Interwencyjnej 2018 11;14(4):363-372. Epub 2018 Dec 11.

Department of Cardiology, School of Health Sciences, Medical University of Silesia, Katowice, Poland.

Introduction: Coronary artery bypass grafting (CABG) is a method of choice in treatment of diffuse coronary artery disease (CAD), although it has some limitations such as late saphenous vein graft (SVG) patency loss, which occurs in one fifth of all conduits at 5 years. Since atherosclerosis in SVG has diffuse characteristics, it appears that significantly and non-significantly stenosed lesions may have an equal impact on worse prognosis.

Aim: To assess non-significant lesions of SVG by the use of optical coherence tomography (OCT) and investigate the clinical and laboratory findings with the potential impact on plaque composition. Read More

Circ Cardiovasc Interv 2019 Jan;12(1):e007281

Fuwai Hospital, National Center for Cardiovascular Diseases, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.

Background: Trimethylamine N-oxide (TMAO) is reported to promote the pathogenesis of atherosclerosis and be associated with cardiovascular events risk. It is unknown whether plasma TMAO is associated with plaque morphology in patients with acute myocardial infarction. We investigated the relationship between the culprit plaque morphology and plasma TMAO concentration in patients with ST-segment-elevation myocardial infarction. Read More

Ann Cardiothorac Surg 2018 Nov;7(6):731-740

Heart Valve Clinic, University Hospital of Zürich, University of Zürich, Zürich, Switzerland.

The field of mitral valve disease diagnosis and management is rapidly evolving. New understanding of pathophysiology and improvements in the adoption of sophisticated multimodality imaging modalities have led to early diagnosis and to more complex treatment. The most common cause of mitral regurgitation (MR) in the western world is in the primary alteration of the valve, which leads to degenerative leaflet prolapse due to chordal elongation or rupture and annular dilatation. Read More

J Vasc Surg 2018 Dec 28. Epub 2018 Dec 28.

Department of Vascular Surgery, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio.

Objective: Iliac conduits (ICs) are used for challenging iliac access during endovascular aortic aneurysm repair (EVAR) with contradictory reports of safety and increased surgical complications, morbidity, and mortality in national database reviews. The objective of this study was to examine outcomes related to IC placement before or concomitant with EVAR at a high-volume single center.

Methods: A retrospective analysis of patients who underwent IC placement for endovascular aortic repair from 2006 to 2016 was conducted. Read More

Eur J Cardiothorac Surg 2018 Dec 27. Epub 2018 Dec 27.

Department of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Aarhus, Denmark.

Objectives: To investigate the feasibility of reconstruction of the entire mitral valve using a tube graft made of 2-ply small intestinal submucosa extracellular matrix in vitro.

Methods: Seven explanted mitral valves with intact subvalvular apparatus from 80 kg pigs were evaluated in a left heart simulator and served as controls. After testing the native valve, the leaflets and chordae tendineae were explanted, and the 2-ply small intestinal submucosa extracellular matrix (CorMatrix®; Cardiovascular Inc. Read More

J Cardiol Cases 2018 Dec 7;18(6):189-191. Epub 2018 Dec 7.

Hyogo Prefectural Awaji Medical Center, Japan.

A 73-year-old woman in cardiogenic shock was referred to our hospital because of papillary muscle rupture immediately after the onset of acute myocardial infarction (MI). She had undergone emergent percutaneous coronary intervention and mitral valve replacement. Serial creatine kinase and creatine kinase MB levels indicated that she had acute phase MI on arrival. Read More

Cell Metab 2018 Dec 20. Epub 2018 Dec 20.

Department of Pathology, Feinberg School of Medicine, Chicago, IL, USA; Feinberg Cardiovascular & Renal Research Institute, Feinberg School of Medicine, Chicago, IL, USA. Electronic address:

During wound injury, efferocytosis fills the macrophage with a metabolite load nearly equal to the phagocyte itself. A timely question pertains to how metabolic phagocytic signaling regulates the signature anti-inflammatory macrophage response. Here we report the metabolome of activated macrophages during efferocytosis to reveal an interleukin-10 (IL-10) cytokine escalation that was independent of glycolysis yet bolstered by apoptotic cell fatty acids and mitochondrial β-oxidation, the electron transport chain, and heightened coenzyme NAD. Read More

Indian Heart J 2018 Dec 7;70 Suppl 3:S431-S434. Epub 2018 Aug 7.

Department of Periodontology, Saraswati Dental College, Lucknow, India.

A high inflammatory state, such as atherosclerosis, is a major underlying cause of coronary heart diseases (CHDs). Inflammatory mediators are known to lead to endothelial dysfunction and play a key role in initiation, progression, and rupture of atherothrombotic plaque. Chronic inflammatory dental infections such as periodontitis and lesions of endodontic origin or chronic apical periodontitis (CAP) may provide an environment conducive for such events. Read More

Indian Heart J 2018 Dec 10;70 Suppl 3:S403-S405. Epub 2018 Nov 10.

Department of Cardiology, U.N.Mehta Institute of Cardiology and Research Centre (UNMICRC), Asarwa, Ahmedabad, 380016, India.

Ventricular septal rupture (VSR) is an uncommon but potentially lethal complication of acute myocardial infarction (MI). Its prompt recognition is essential to permit timely institution of corrective measures. The present study was undertaken to assess the diagnostic accuracy of a novel and unique angiographic sign, the 'winking coronary sign (WCS)', for recognizing post-MI VSR. Read More

Indian Heart J 2018 Dec 6;70 Suppl 3:S347-S352. Epub 2018 Oct 6.

Cardio-Thoracic Vascular Surgery, Apollo Hospital, Greams Road, Chennai, Tamil Nadu, India.

Background: Despite the increasing popularity of transcatheter aortic valve replacement (TAVR), only about 10,000 TAVR cases have been performed in Asia to date. The procedure is still in a nascent stage in India with very few centers offering this state-of-art technique. Here, we present the early results of TAVR experience at our center. Read More

Catheter Cardiovasc Interv 2018 Dec 27. Epub 2018 Dec 27.

Raigmore Hospital, Inverness, United Kingdom.

Saphenous vein graft (SVG) aneurysms are a rare, frequently late presenting, potentially fatal complication of coronary artery bypass graft (CABG) surgery. They are often discovered incidentally during radiological tasks such as chest x-ray or CT but can present clinically with symptoms such as worsening angina and breathlessness as well as complications such as rupture or myocardial infarction. Given the risks if left untreated, consideration should be given to treatment either through percutaneous routes or open surgery. Read More

Circulation 2018 Nov 10. Epub 2018 Nov 10.

Cleveland Clinic, UNITED STATES.

Thoracic aortic aneurysm is a potentially devastating disease that kills by dissection/rupture and exsanguination. However, it is difficult to estimate the true prevalence because many aneurysms are clinically silent and present as sudden death. Death by thoracic aortic aneurysm in the United States occurs at a rate of 3. Read More

Case Rep Vasc Med 2018 21;2018:6273538. Epub 2018 Nov 21.

AtlantiCare Regional Medical Center, USA.

We present a case of a 78-year-old female with history of diastolic heart failure and paroxysmal atrial fibrillation on apixaban presenting with worsening shortness of breath. She underwent transesophageal echocardiogram showing severe aortic stenosis with a valve area of 0.8 cm2. Read More

J Vasc Surg 2018 Dec 21. Epub 2018 Dec 21.

Division of Vascular Surgery, Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pa.

Objective: Open procedures are often required for late complications after endovascular aneurysm repair (EVAR). Our aim was to describe the indications for open interventions and their postoperative outcomes and to specifically examine our experience with limited conversions in which problem endoleaks are targeted without endograft explantation.

Methods: We reviewed patients from 2002 to 2017 who underwent any surgical abdominal aortic operation after a previous EVAR. Read More

Case Rep Crit Care 2018 19;2018:1568491. Epub 2018 Nov 19.

Cardiac Arrest Center, Department of Cardiology and Angiology, Hannover Medical School, Hannover, Germany.

A 66-year-old patient was admitted under continuous resuscitation for pulseless electrical activity. After return of spontaneous circulation ECG showed signs of acute inferior ST-elevation myocardial infarction, and echocardiography showed acute right ventricular failure with a dilated right ventricle. Carotid pulses were present in the absence of femoral pulses. Read More

Indian Heart J 2018 Nov - Dec;70(6):894-900. Epub 2017 Dec 11.

Department of Anatomy, Institute of Post Graduation Medical Education & Research, 244, A.J.C Bose Road, Kolkata-700020, West Bengal, India. Electronic address:

Introduction: The two left ventricular papillary muscles are small structures at sternocostal and inferior wall but are vital to mitral valve competence. Extra papillary muscles could be found. Partial or complete rupture, complicating acute myocardial infarction, causes severe or even catastrophic mitral regurgitation, potentially correctable by surgery. Read More

Expert Opin Investig Drugs 2018 Dec 22:1-12. Epub 2018 Dec 22.

a Division of Cardiology, Department of Medicine , Westchester Medical Center and New York Medical College , Valhalla , NY , USA.

Background: Advances in our understanding of the complex pathophysiologic mechanisms responsible for high-risk atherosclerotic plaque rupture resulting in acute myocardial infarction (AMI) have led to the development of numerous antiplatelet and anticoagulant agents for treatment of AMI. Areas covered: We review various antithrombotic drugs which were recently investigated for the treatment of AMI. A MEDLINE search for relevant articles on newer antiplatelet agents and anticoagulants drugs for the treatment of AMI was performed, and important original investigations were reviewed. Read More

J Obstet Gynaecol Can 2018 Dec 18. Epub 2018 Dec 18.

Department of Obstetrics & Gynecology, King Fahad Hospital of the University, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

Objective: This study sought to evaluate the safety of induction of labour with prostaglandin E (PGE) gel in grand multigravida (GMG) women and to compare the labour outcome of GMG women with that of women who never had a previous Caesarean section (CS).

Methods: This prospective cohort study (Canadian Task Force Classification II-2) evaluated induction of labour with 1 mg of PGE gel in 96 GMG women with one previous CS (study group) and in 104 GMG women without previous CS (control group).

Results: One uterine rupture occurred in the study group (1%), and another occurred in the control group (0. Read More

Vasc Endovascular Surg 2018 Dec 20:1538574418819540. Epub 2018 Dec 20.

1 Department of Cardiovascular Surgery, Hyogo Brain and Heart Center at Himeji, Himeji, Hyogo, Japan.

New-onset antegrade Stanford type B aortic dissection (TBAD) after endovascular aneurysm repair (EVAR) for abdominal aortic aneurysm (AAA) is rare. The extension of aortic dissection leads to various symptoms and affects the stent graft. Moreover, various symptoms may arise owing to a stent graft being present. Read More

Zhonghua Xin Xue Guan Bing Za Zhi 2018 Dec;46(12):981-986

Department of Cardiology, Second Xiangya Hospital of Central South University, Changsha 410011, China.

To assess the clinical characteristics and identify the risk factors in the acute myocardial infarction (AMI) patients complicating with ventricular septal rupture (VSR). A retrospective study was performed on 96 AMI patients complicating with VSR, who were hospitalized in the Second Xiangya Hospital of Central South University, Hunan Provincial Peoples' Hospital, the First Affiliated Hospital of University of South China, the Second Affiliated hospital of University of south China, Xiangtan Central Hospital from December 2007 to May 2017. There were 46 females and the age was (66. Read More

Clin Cardiol 2018 Dec 18. Epub 2018 Dec 18.

Coronary Artery Disease Area, Heart and Vascular Theme, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.

Thrombo-embolism is one of the serious complications of takotsubo syndrome (TS) in addition to heart failure, pulmonary edema, cardiogenic shock, cardiac arrest, life-threatening arrhythmias, left ventricular outlet tract obstruction, mitral regurgitation, cardiac rupture, and death. The most common cardio-embolic events in TS are cerebral, renal, and peripheral embolism. Approximately, one-third of patients with left ventricular thrombus (LVT) in TS develop embolic complications. Read More

Cardiovasc Intervent Radiol 2018 Dec 18. Epub 2018 Dec 18.

Department of Vascular Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Zhongshan Road 321, Nanjing, 210008, People's Republic of China.

Objective: To compare the short-term efficiency of two different endovascular repairs for type B aortic dissection involving the left subclavian artery.

Methods: From February 2013 to March 2016, a cohort of 43 patients with TBADs involving the LSA underwent thoracic endovascular aortic repair (TEVAR) in two departments, consisting of 22 (Group A) with chimney grafts (CGs) and 21 (Group B) with single-branched stent graft (SBSG). Results of the two groups in perioperative and follow-up period (≥ 3 months) were comparatively analyzed, especially on aortic remodeling. Read More

J Heart Valve Dis 2018 Jan;27(1):110-113

Imam Abdulrahman bin Faisal University, College of Medicine, Internal Medicine Department, Saudi Arabia. Electronic correspondence:

Graves' disease is a common cause of hyperthyroidism that can lead to multiple cardiovascular complications. Herein is described the case of a 44-year-old male who presented with new-onset atrial fibrillation and mitral regurgitation secondary to flail anterior mitral leaflet with chordae tendineae rupture. This is a rare complication for Graves' disease, and has been reported only twice previously. Read More

J Vasc Surg Venous Lymphat Disord 2019 Jan 24;7(1):65-73. Epub 2018 Oct 24.

Interventional Radiology, ProMedica Toledo Hospital, Toledo, Ohio.

Objective: Chronic, post-thrombotic iliofemoral and inferior vena caval obstruction is associated with debilitating morbidity. Venoplasty and stenting are often successful; however, in the presence of a diseased or occluded common femoral vein (CFV), failure is common. A hybrid operative procedure of open surgical CFV endovenectomy and endoluminal recanalization or bypass of the obstructed iliofemoral and vena caval segments has been developed and modified. Read More

Medicine (Baltimore) 2018 Dec;97(50):e13669

Department of Cardiology Center, Hebei General Hospital, Shijiazhuang, Hebei Province, China.

Rationale: Primary percutaneous coronary intervention (PPCI) with immediate stenting provides effective revascularization. While the risks of no-reflow, stent thrombosis, stent undersizing, and malapposition reduced the benefits in patients with high burden thrombosis. Intravascular imaging, especially optical coherence tomography (OCT), offers potential in optimization of percutaneous coronary intervention. Read More

Eur J Obstet Gynecol Reprod Biol 2018 Dec 5;233:30-37. Epub 2018 Dec 5.

Department of Obstetrics and Gynecology, Hôpital Femme Mère Enfant, Hospices Civils de Lyon, Lyon, France.

Objectives: Preterm premature rupture of fetal membranes (PPROM) exposes the fetus to preterm birth, and optimal timing for delivery is controversial. The aim of this study was to compare intentional early delivery ("active management") with expectant management in very preterm birth (28-32 weeks).

Study Design: We conducted a prospective randomized controlled trial with intent-to-treat analysis, at 19 tertiary-care hospitals in France and 1 in Geneva, Switzerland. Read More

Multimed Man Cardiothorac Surg 2018 Dec 6;2018. Epub 2018 Dec 6.

Department of Thoracic and Cardiovascular Surgery Mie University Graduate School of Medicine 2-174 Edobashi, Tsu, Mie 514-8507, Japan.

Papillary muscle rupture is a rare complication after myocardial infarction and almost all cases occur in the mitral valve papillary muscle. Tricuspid regurgitation development after right ventricular myocardial infarction caused by papillary muscle rupture is extremely rare.  In this video tutorial we present a 70-year-old man with massive tricuspid regurgitation caused by papillary muscle rupture after percutaneous stenting of the right coronary artery. Read More

Open Forum Infect Dis 2018 Nov 20;5(11):ofy265. Epub 2018 Oct 20.

Division of Infectious Diseases, Atlanta, Georgia.

Background: The use of valve surgery for infective endocarditis (IE) in end-stage renal disease (ESRD) patients may be different than in the general population. We assessed predictors of early surgery in ESRD patients with IE.

Methods: We conducted a retrospective cohort study among dialysis patients with left-sided IE between 2005 and 2015. Read More

J Cell Physiol 2018 Dec 7. Epub 2018 Dec 7.

Department of Cardiovascular Surgery, Henan Provincial People's Hospital, Zhengzhou, P. R. China.

Cardiac rupture and ventricular remodeling are recognized as the severe complications and major risk factors of acute myocardial infarction (AMI). This study aims to evaluate the regulatory roles of interleukin-1 receptor-associated kinase 3 (IRAK3) and nuclear factor-κB (NF-κB) signaling pathway in cardiac rupture and ventricular remodeling. Microarray analysis was performed to screen AMI-related differentially expressed genes and IRAK3 was identified. Read More

JAMA 2018 12;320(22):2325-2334

Hemodialysis Center, Inoue Hospital, Soryu Medical Corporation, Osaka, Japan.

Importance: Patients with chronic kidney disease have impaired vitamin D activation and elevated cardiovascular risk. Observational studies in patients treated with hemodialysis showed that the use of active vitamin D sterols was associated with lower risk of all-cause mortality, regardless of parathyroid hormone levels.

Objective: To determine whether vitamin D receptor activators reduce cardiovascular events and mortality in patients without secondary hyperparathyroidism undergoing hemodialysis. Read More

Semin Thorac Cardiovasc Surg 2018 Dec 8. Epub 2018 Dec 8.

Department of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Centre Essen, University Hospital of Essen, University of Duisburg-Essen, Essen, Germany.

Acute type I aortic dissection (AD) complicated by true lumen (TL) collapse and malperfusion downstream is associated with devastating prognosis. The study reports an institutional mid-term experience with TL stabilization by uncovered stents to restore perfusion as a supplement to proximal thoracic aortic surgery. Between January 2007 and May 2017, 181 out of 270 acute type A AD patients were operated on type I AD. Read More