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Microorganisms 2022 Jun 5;10(6). Epub 2022 Jun 5.

Scientific Research Institute for Systems Biology and Medicine, 117246 Moscow, Russia.

Mycoplasmas are pathogenic, genome-reduced bacteria. The development of such fields of science as system and synthetic biology is closely associated with them. Despite intensive research of different representatives of this genus, genetic manipulations remain challenging in mycoplasmas. Read More

Front Microbiol 2022 2;13:904494. Epub 2022 Jun 2.

TU Dresden, Institute of Medical Microbiology and Virology, Dresden, Germany.

and are cell wall-less bacteria with strongly reduced genome content and close phylogenetic relatedness. In humans, the only known natural host, the microorganisms colonize the respiratory or genitourinary mucosa and may cause a broad range of clinical presentations. Besides fundamental differences in their tissue specificity, transmission route, and ability to cause prevalence peaks, both species share similarities such as the occurrence of asymptomatic carriers, preferred populations for infection, and problems with high rates of antimicrobial resistance. Read More

AMB Express 2022 Jun 15;12(1):76. Epub 2022 Jun 15.

College of Veterinary Medicine, Henan Agricultural University, Zhengzhou, China.

Canine parvovirus-2 (CPV-2) infection causes serious multisystemic disease in dogs and many animal species worldwide. Previously, a monoclonal antibody (MAb) of CPV-2, 10H4, showed high neutralizing activity and therapeutic effect against CPV-2 in dogs. However, the application of mouse MAb is limited in other animals due to immune rejection. Read More

Sex Transm Infect 2022 Jun 16. Epub 2022 Jun 16.

WHO Collaborating Centre for Gonorrhoea and Other STIs, Department of Laboratory Medicine, Orebro universitet, Orebro, Sweden

Objectives: Antimicrobial resistance in (MG) is a poorly surveyed and controlled global health concern. We evaluated the first commercial dual resistance assay, AmpliSens -ML/FQ-Resist-FL assay, for detection of potential macrolide and quinolone resistance-associated mutations (MRAMs and QRAMs, respectively) and estimated the prevalence of these mutations in MG in St. Petersburg, Russia. Read More

Clin Lab 2022 Jun;68(6)

Background: The aim of this study was to investigate the infection and antimicrobial resistance of Ureaplasma urealyticum (U. urealyticum) and Mycoplasma hominis (M. hominis) in patients with genital tract diseases in Jiangsu, China. Read More

J Wildl Dis 2022 Jun 15. Epub 2022 Jun 15.

University of Maine, School of Food and Agriculture, 5735 Hitchner Hall, Orono, Maine 04469, USA.

Growing populations of Wild Turkeys (Meleagris gallopavo) may result in increased disease transmission among wildlife and spillover to poultry. Lymphoproliferative disease virus (LPDV) is an avian retrovirus that is widespread in Wild Turkeys of eastern North America, and infections may influence mortality and parasite co-infections. We aimed to identify individual and spatial risk factors of LPDV in Maine's Wild Turkeys. Read More

J Wildl Dis 2022 Jun 15. Epub 2022 Jun 15.

Department of Veterinary Sciences, University of Wyoming, 1174 Snowy Range Road, Laramie, Wyoming 82070, USA.

Mycoplasma bovis is an economically important bacterial pathogen of cattle (Bos taurus) and bison (Bison bison) that most commonly causes pneumonia, polyarthritis, and mastitis. It is prevalent in cattle and ranched bison; however, infections in other species are rare. In early 2019, we identified M. Read More

Sci Rep 2022 Jun 14;12(1):9900. Epub 2022 Jun 14.

Faculty of Veterinary Science, Prince of Songkla University, Hat Yai, Kho Hong, Songkhla, 90110, Thailand.

Mycoplasma gallisepticum (MG) is one of the most economically important pathogens worldwide. MG affects the respiratory system and impairs growth performance in poultry. In developing countries, the most widely used technique to identify MG is the conventional PCR assay. Read More

Access Microbiol 2022 21;4(3):000332. Epub 2022 Mar 21.

Pediatrics Department, King Hamad University Hospital, Busaiteen, Bahrain.

Respiratory tract infections are a leading cause of hospital visits in the paediatric population and carry significant associated morbidity and mortality in this population. The introduction of respiratory panel testing has been said to guide clinicians in the overall management of patients. We conducted a retrospective study examining all respiratory panels carried out in our hospital during 2019 on paediatric patients. Read More

Front Surg 2022 25;9:897550. Epub 2022 May 25.

Department of Pediatrics, The First People's Hospital of Linping District, Hangzhou, China.

Objective: To investigate the clinical characteristics of children with severe Mycoplasma pneumoniae pneumonia (SMPP) and the correlation with pediatric critical illness score (PICS), and to explore the effect of combined treatment with antibiotics and glucocorticoids.

Methods: The medical records of 120 children with SMPP admitted to our hospital from January 2020 to June 2021 were retrospectively analyzed. Children with a PICS score greater than 80 within 24 h of admission were included in the non-critical group, those with a score of 71-80 were included in the critical group, and those with a score of ≤70 were included in the extremely critical group. Read More

Infez Med 2022 1;30(2):247-253. Epub 2022 Jun 1.

Department of Microbiology, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran.

Bacterial vaginosis is a condition caused by changes in the vaginal microbial ecosystem and increases the risk of preterm delivery, premature rupture of membranes, endometritis, and weight loss of the baby. This study aimed to evaluate the frequency of gonococcal and non-gonococcal genital infections in women referred to clinics in Ilam, Iran. Two swab samples were taken from each patient using a sterile swab, one swab was placed in a THB medium for the culture of and the other in PBS buffer for PCR. Read More

Vet Res 2022 Jun 13;53(1):41. Epub 2022 Jun 13.

Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna, Via Bianchi, 9, 25124, Brescia, Italy.

Little is known about how co-infections and genotype dynamics affect Mycoplasma hyopneumoniae infection in fattening pigs. This study was aimed at assessing the role of co-infections in M. hyopneumoniae outbreaks, their influence on the presence of M. Read More

Ann Dermatol Venereol 2022 Jun 8. Epub 2022 Jun 8.

Department of Dermatology, Genital Diseases and STIs unit, Saint-Louis Hospital, 1, avenue Claude Vellefaux, 75010 Paris, France.

Objective: Mycoplasma genitalium (MG) infection accounts for 10-35% of non-gonococcal non-chlamydial (NGNC) urethritis. However, given that most people infected with MG do not develop symptoms and that antimicrobial resistance is increasing worldwide, there is no evidence of any benefits of screening asymptomatic individuals. We conducted this study to describe MG screening practices and outcomes at a French Sexually Transmitted Infections (STI) center in which MG testing was performed selectively and multiplex assays were not carried out [i. Read More

Transl Pediatr 2022 May;11(5):625-630

Department of Clinical Laboratory, Northwest Women's and Children's Hospital, Xi'an, China.

Background: () is an important pathogen that causes respiratory tract infections in children. Data on epidemiology of paediatric infection in China are little known. The aim of this study was to investigate the infection of children with respiratory tract infection in Xi'an from 2017 to 2020, and to explore the epidemiological features of paediatric infection in Northwest China during the past 4 years. Read More

Animals (Basel) 2022 May 27;12(11). Epub 2022 May 27.

Sydney School of Veterinary Science, The University of Sydney, Camden, NSW 2570, Australia.

(formerly ) is a haemotropic parasitic bacterium found within erythrocytes and distributed widely in global sheep and goat production regions. is transmitted by biting flies and by contaminated instruments, causing morbidity and mortalities from anaemia, usually within 6 weeks following blood-exposure procedures, particularly vaccination, castration, ear tagging, mulesing, and occasionally crutching and shearing. Affected animals develop haemolytic anaemia and may have jaundice, causing abattoir condemnations. Read More

Porcine Health Manag 2022 Jun 9;8(1):26. Epub 2022 Jun 9.

Department of Internal Medicine, Reproduction and Population Medicine, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.

Background: Dam-to-piglet transmission plays an important role in the epidemiology of enzootic pneumonia on farms. Although Mycoplasma hyopneumoniae (M. hyopneumoniae) infections in breeding animals are often subclinical, their control could have a positive effect on M. Read More

World J Microbiol Biotechnol 2022 Jun 7;38(7):128. Epub 2022 Jun 7.

Animal Health Unit, Department of Health and Environmental Sciences, School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Japan.

The study aimed to develop a pair of polymerase chain reaction primers for detecting ruminant mycoplasma pathogens. We designed a set of primers based on the most similar sequences within 16 S rRNA regions of seven Mycoplasma spp. These primers have high sensitivity for detecting Mycoplasma dispar, M. Read More

Am J Case Rep 2022 Jun 3;23:e936264. Epub 2022 Jun 3.

Department of Internal Medicine, Detroit Medical Center Sinai Grace Hospital, Detroit, USA.

BACKGROUND Legionella infection is a common cause of atypical pneumonia, known as Legionnaires' disease when infection extends to extrapulmonary involvement, which often leads to hospitalization. The triad of Legionella pneumonia, rhabdomyolysis, and renal failure displays a rare yet fatal complication without prompt management. CASE REPORT Our patient was a 62-year-old man with no significant medical history who developed Legionnaires' disease with severely elevated creatinine phosphokinase (CPK) of 9614 mcg/L, consistent with rhabdomyolysis. Read More

Front Cell Infect Microbiol 2022 13;12:855731. Epub 2022 May 13.

The State Key Laboratory of Agricultural Microbiology, (HZAU), Wuhan, China.

Mycoplasmas as economically important and pantropic pathogens can cause similar clinical diseases in different hosts by eluding host defense and establishing their niches despite their limited metabolic capacities. Besides, enormous undiscovered virulence has a fundamental role in the pathogenesis of pathogenic mycoplasmas. On the other hand, they are host-specific pathogens with some highly pathogenic members that can colonize a vast number of habitats. Read More

Int J Fertil Steril 2022 Apr 8;16(2):95-101. Epub 2022 May 8.

Department of Microbiology, Faculty of Medicine, Shahed University, Tehran, Iran.

Background: is an important cause of bacterial infections of the genital tract. Macrolides are the first selective agents used to treat mycoplasma infections. However, widespread use of macrolides has led to a rapid and global emergence of macrolide-resistant strains. Read More

BMC Pulm Med 2022 May 30;22(1):212. Epub 2022 May 30.

Department of Pediatrics, Chonnam National University Hospital, Chonnam National University Medical School, Jebong-ro, Dong-gu, Gwangju, 61469, Republic of Korea.

Background: The prevalence of refractory Mycoplasma pneumoniae (MP) pneumonia has been increasing. However, few studies have investigated the impact of respiratory virus coinfection in patients with MP pneumonia, and their results have been inconclusive. This study aimed to investigate the impact of respiratory virus coinfection in children hospitalized with MP pneumonia. Read More

Front Microbiol 2022 13;13:811768. Epub 2022 May 13.

The Affiliated Nanhua Hospital, Department of Clinical Laboratory, Hengyang Medical School, University of South China, Hengyang, China.

Mycoplasma pneumoniae can cause severe respiratory tract infections and extrapulmonary diseases, which pose a significant threat to the health of children. Diagnostic methods for include isolation and culture, antibody detection, fluorescence quantitative PCR, and so on, but there are various shortcomings in time, cost, convenience, and sensitivity. In this study, we developed a rapid, sensitive, specific, and economical method for the detection of , termed the ERA/CRISPR-Cas12a dual system. Read More

Diagnostics (Basel) 2022 May 4;12(5). Epub 2022 May 4.

Institute of Microbiology, Lausanne University Hospital and University of Lausanne, CH-1011 Lausanne, Switzerland.

is an important cause of sexually transmitted infections (STI) in Western countries. It is often asymptomatic, and thus, left untreated, and can have severe negative consequences, such as tubal infertility or adverse pregnancy outcomes. Other sexually transmitted microorganisms, such as and , as well as normal residents of the vaginal flora, such as genital mycoplasmas, also negatively impact human sexual and reproductive health. Read More

Int J STD AIDS 2022 May 27:9564624221103808. Epub 2022 May 27.

Public Medical Center (CMP), DPASS South Province, Nouméa, New Caledonia.

Background: The prevalence of sexually transmitted infections (STIs) is high in New Caledonia (NC), but there are no data on (MG). However, the syndromic treatment of urethritis used in the territory includes a single dose of azithromycin, which could generate resistance in MG.

Methods: We recruited 217 men referred to the Noumea public medical centre (CMP) with signs of urethritis and meeting the inclusion criteria from May 2016 to March 2018. Read More

J Vet Sci 2022 May;23(3):e49

Department of Infectious Diseases, College of Veterinary Medicine, Seoul National University, Seoul 08826, Korea.

Background: Porcine circovirus type 2 (PCV2) and (MHP) are economically significant pathogens in the pig industry. The use of combined vaccines against PCV2 and MHP is one of the most effective ways of protecting pigs from both diseases, and it has become a part of general management.

Objectives: This study evaluated the efficacy of two new bivalent vaccines of PCV2 and MHP (Myco-X and Myco-XD) in SPF pigs. Read More

Sex Health 2022 May 27. Epub 2022 May 27.

Mycoplasma genitalium is an emerging sexually transmitted bacterium that is gaining attention because of the impact escalating antimicrobial resistance (AMR) is having on patient management. Of additional concern is that increased availability of testing appears to be resulting in screening practices that are not supported by clinical guidelines. This results in increasing numbers of asymptomatic M. Read More

J Med Microbiol 2022 May;71(5)

RuminAção - Teaching, Research and Extension in Ruminants, School of Veterinary, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.

Infectious keratoconjunctivitis is a significant ocular disease found in confined sheep. Little information about the aetiological agents and their antimicrobial susceptibility is available. There is limited information on the aetiological agents involved in keratoconjunctivitis outbreaks in sheep. Read More

Int J STD AIDS 2022 May 24:9564624221100098. Epub 2022 May 24.

Department of Pathology, 12246The University of Chicago, Chicago, IL, USA.

Background: Screening for and is recommended for individuals at high-risk for sexually transmitted infections (STIs), while the role of screening is still unclear. We evaluated whether specimen pooling is an effective alternative for sexually transmitted infection testing during resource shortages.

Methods: This 2-year prospective study enrolled 135 asymptomatic patients from a community outreach site who identified as men who have sex with men. Read More

mBio 2022 May 24:e0091822. Epub 2022 May 24.

Department of Biomedical Sciences, University of Sassarigrid.11450.31, Sassari, Italy.

Trichomonas vaginalis can host the endosymbiont Mycoplasma hominis, an opportunistic pathogenic bacterium capable of modulating T. vaginalis pathobiology. Recently, a new noncultivable mycoplasma, " Mycoplasma girerdii," has been shown to be closely associated with women affected by trichomoniasis, suggesting a biological association. Read More

Contrast Media Mol Imaging 2022 4;2022:6460865. Epub 2022 May 4.

Department of Pharmacy, Yiwu Central Hospital, Yiwu 322000, Zhejiang, China.

The aim of this study was to investigate the value of high-resolution computed tomography (CT) images and mycoplasma (MP) ribonucleic acid (RNA) load detection in the early diagnosis of refractory mycoplasma (RMP) and provide more methods for the diagnosis and treatment of RMP. Seventy children with MP were divided into the RMP group (H1 group, 31 cases) and the MP group (H2 group, 39 cases) according to pathological findings, and all of them underwent CT scanning. MP-RNA load and genotype distribution were analyzed in both groups, and the diagnostic efficacy of CT combined with MP-RNA load for RMP was calculated. Read More