Search Our Scientific Publications & Authors

PLoS One 2019 23;14(4):e0215001. Epub 2019 Apr 23.

Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.

The anogenital prevalence of sexually transmitted infections (STIs) and the use of cervico-vaginal self-collected vs. clinician-collected samples were evaluated for the diagnosis of human immunodeficiency virus (HIV)-infected and HIV-uninfected women in the Tapajós region, Amazon, Brazil. We recruited 153 women for a cross-sectional study (112 HIV-uninfected and 41 HIV-infected) who sought health services. Read More

J Anim Sci 2019 Apr 23. Epub 2019 Apr 23.

Department of Animal Sciences, University of Illinois, Urbana, IL.

Porcine reproductive and respiratory syndrome virus (PRRSV) is the most prevalent disease of swine globally. Infection of weanling pigs with PRRSV leads to a complex immune response resulting in significant disease and decreased growth performance. Previous experimental evidence suggests that increasing concentrations of soybean meal in the diet of young pigs confers benefits in terms of growth performance and immune parameters. Read More

Sex Transm Dis 2019 Apr 17. Epub 2019 Apr 17.

Sydney Sexual Health Centre, Sydney, New South Wales, Australia Centre for Infectious Diseases and Microbiology Laboratory Services, ICPMR - NSW Health Pathology, Westmead, Australia Sydney Sexual Health Centre, Sydney, New South Wales, Australia; School of Public Health and Community Medicine, University of New South Wales, Sydney, Australia Centre for Infectious Diseases and Microbiology Laboratory Services, ICPMR - NSW Health Pathology, Westmead, Australia Centre for Infectious Diseases and Microbiology Laboratory Services, ICPMR - NSW Health Pathology, Westmead, Australia Western Sydney Sexual Health Centre, Parramatta, New South Wales, Australia Western Sydney Sexual Health Centre, Parramatta, New South Wales, Australia; Marie Bashir Institute for Infectious Diseases and Biosecurity, University of Sydney, Australia.

Background: Mycoplasma genitalium was previously less common among men who have sex with men (MSM) compared with men with only female partners (MSW) in men with nongonococcal urethritis (NGU) in Sydney, Australia. We aimed to determine the prevalence of M. genitalium and of macrolide-resistant M. Read More

J Obstet Gynaecol 2019 Apr 22:1-5. Epub 2019 Apr 22.

c Department of Obstetrics and Gynaecology , Nnamdi Azikiwe University Teaching Hospital , Nnewi , Nigeria.

Here, we aimed to investigate the predominance of cervicitis agents with minimal testing rates among asymptomatic students in a Tertiary Institution and its associated risk factors. Endocervical swabs were collected from randomly selected 133 female students (15-34 years of age) in Benin City, Nigeria and screened for six genital pathogens (Chlamydia trachomatis, Mycoplasma hominis, M. genitalium, Ureaplasma urealyticum, U. Read More

Poult Sci 2019 Apr 19. Epub 2019 Apr 19.

Institute of Micromechanics and Photonics, Faculty of Mechatronics, Warsaw University of Technology, 02-525 Warsaw, Poland.

Mycoplasma synoviae (MS) is a major pathogen in chicken and turkeys, causing subclinical infection. MS infections are highly prevalent and may potentate and be involved in sinovitis, respiratory syndromes, as well as lead to eggshell apex abnormality (EAA). A deformed, inhomogeneous eggshell is susceptible to cracks and breaks through which microbes get in and additionally entails higher water loss in the egg during the entire incubation process. Read More

Korean J Pediatr 2019 Mar 15. Epub 2019 Mar 15.

Pediatric Allergy and Respiratory Center, Department of Pediatrics, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, Korea.

Mycoplasma pneumoniae pneumonia (MPP) has been generally susceptible to macrolides, however emergence of macrolide-resistant Mycoplasma pneumoniae pneumonia (MRMP) has made the treatment of MPP challenging. MRMP rapidly spread after 2000s, especially in the Eastern Asia. MRMPs are more common in children and adolescents than in adults, which is likely related to the frequent use of macrolides for treatments of MP infections in children. Read More

Medicine (Baltimore) 2019 Apr;98(15):e15118

Third Unit of Pediatric Department, Yanan University Affiliated Hospital, Yan'an, China.

Background: Several clinical studies have reported that inflammation factors (IF) are associated with Mycoplasma pneumoniae in children. However, no study systematically investigated the association between IF and M pneumoniae in pediatric population. Thus, this study will explore the association between IF and pediatric M pneumoniae systematically. Read More

Pediatr Infect Dis J 2019 Apr 10. Epub 2019 Apr 10.

From the Department of Clinical Microbiology and Infectious Diseases, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

Background: Mycoplasma pneumoniae (MP) is a major cause of community-acquired upper and lower respiratory infections in school-age children; however, there is increasing recognition that younger children are also affected. Clinical manifestations vary from asymptomatic, to severe complicated pneumonia sometimes with extrapulmonary manifestations.

Methods: We reviewed the medical records of all MP positive pediatric patients admitted to the Hadassah-Hebrew University Medical Center. Read More

J Microbiol Methods 2019 Apr 11;161:1-7. Epub 2019 Apr 11.

Department of Microbiology, Faculty of Veterinary Medicine, Selcuk University, Konya, Turkey. Electronic address:

Mycoplasma spp. can cause diseases of the respiratory system as well as urogenital infections, infertility, and anemia. The members of this genus have a low G + C content compared to other bacteria. Read More

J Vet Diagn Invest 2019 Apr 11:1040638719843638. Epub 2019 Apr 11.

Departments of Biomedical Sciences (Bolfa, Callanan, Ketzis, Marchi, Cheng, Huynh, Lavinder, Boey).

Free-roaming chickens on Caribbean islands are important sentinels for local avian diseases and those introduced by birds migrating through the Americas. We studied 81 apparently healthy unvaccinated free-roaming chickens from 9 parishes on St. Kitts, an eastern Caribbean island. Read More

J Vet Diagn Invest 2019 Apr 11:1040638719844297. Epub 2019 Apr 11.

California Animal Health and Food Safety Laboratory System, School of Veterinary Medicine, University of California-Davis, Davis, CA.

Infectious coryza is a severe respiratory disease of chickens associated with large economic losses in affected commercial flocks. The fastidious causative pathogen, Avibacterium paragallinarum, is difficult to recover and identify, resulting in delayed diagnosis and enhanced spread of the agent. Small poultry flocks are increasingly common in rural and suburban environments. Read More

Clin Infect Dis 2019 Apr 11. Epub 2019 Apr 11.

Departments of Medicine, Division of Infectious Diseases and Immunology University of Massachusetts Medical School, Worcester, MA, United States.

Background: Mycoplasma genitalium (Mg) causes symptomatic urethritis in men, and can infect alone or together with other STI agents.

Methods: The prevalence of Mg and other STIs were determined in 1816 men with symptomatic urethritis. Resistance of Mg to macrolides and fluoroquinolones was determined by sequencing; the impact of recent antimicrobial usage on the distribution of Mg single or mixed infections was determined. Read More

Biomed Rep 2019 Apr 15;10(4):231-237. Epub 2019 Feb 15.

Department of Microbiology, 'Aretaieion' General Hospital, National and Kapodistrian University of Athens, Athens 11528, Greece.

Assisted reproductive techniques including fertilization (IVF) are being used increasingly worldwide and screening for genital tract infections (GTIs) is recommended prior to treatment as their presence may affect the success rate of IVF. The current study aimed to assess the possible associations between GTI-associated factors and reproductive outcome in a group of reproductive age fertile females and infertile females receiving IVF. A total of 111 infertile women enrolled in an IVF programme (Group A) and 104 fertile women (mothers of at least one child; Group B) underwent microbiological screening of vaginal and cervical samples. Read More

Comp Immunol Microbiol Infect Dis 2019 Apr 22;63:148-153. Epub 2019 Jan 22.

IHAP, Pathogenesis of Mycoplasma Infections, University of Toulouse, INRA, ENVT, 23 chemin des Capelles, 31076, Toulouse Cedex, France. Electronic address:

Mycoplasma wenyonii, a hemoplasma infecting cattle, was never detected in France. In 2014, evocative inclusions were observed in erythrocytes from cattle presenting milk drops, anemia, and edema in Brittany (France). A survey was then initiated to investigate the epidemiological situation and correlate mycoplasma detection with clinical signs. Read More

Arch Gynecol Obstet 2019 Apr 5. Epub 2019 Apr 5.

Scientific and Medical Department, Medinova AG, Zurich, Switzerland.

Introduction: Bacterial vaginosis (BV) is the most common vaginal disorder in reproductive-age women. The condition is characterised by the replacement of a healthy, lactobacilli-dominated vaginal microbiota by anaerobic and facultative anaerobic bacteria. BV increases the risk of acquisition of STIs and is associated with pregnancy complications. Read More

Pediatr Allergy Immunol 2019 Apr 5. Epub 2019 Apr 5.

University of Belgrade-Faculty of Medicine, Belgrade, Serbia.

Background: Antiepileptic drugs (AEDs) can cause hypersensitivity reactions in children. These reactions are mainly cutaneous, self-limiting and benign but life-threatening severe cutaneous adverse reactions can occur. Infections can lead to skin eruptions and mimic drug hypersensitivity reactions, if a drug is taken at the same time. Read More

BMJ Open 2019 Apr 3;9(4):e028145. Epub 2019 Apr 3.

Department of Clinical Sciences, HIV/STI Reference Laboratory, Institute of Tropical Medicine, Antwerp, Belgium.

Objectives: Pre-exposure prophylaxis (PrEP) users are screened bi-annual for sexually transmitted infections (STIs). A novel device, called the Colli-Pee, collects first-void urine in a standardised way and the collector tube can be easily delivered by regular post to a certified laboratory. The aim of the study was a one-to-one comparison between the STI test results obtained with the urine collected in the clinic, versus urine collected at home in a real-life setting by Men who have Sex with Men (MSM) in Belgium. Read More

PLoS One 2019 4;14(4):e0213975. Epub 2019 Apr 4.

Institute of Infectious Disease and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.

The genital tract of African women has been shown to differ from what is currently accepted as 'normal', defined by a pH≤4.5 and lactobacilli-dominated microbiota. Adolescent girls and young women (AGYW) from sub-Saharan Africa are at high risk for HIV, and we hypothesized that specific biological factors are likely to be influential. Read More

AMB Express 2019 Apr 3;9(1):43. Epub 2019 Apr 3.

Department of Molecular Biotechnology and Microbiology, Faculty of Science and Technology, University of Debrecen, 1 Egyetem Square, Debrecen, 4010, Hungary.

Studies of morphological measurements from the outgrowth of cells to a network of hyphae have been extended from Candida albicans (Nagy et al. in Appl Microbiol Biotechnol 98(11):5185-5194. https://doi. Read More

Emerg Med Clin North Am 2019 May;37(2):165-192

Prisma Health, University of South Carolina School of Medicine Greenville, 701 Grove Road, Greenville, SC 29605, USA. Electronic address:

Sexually transmitted diseases (STDs) continue to be underrecognized leading to devastating health and economic consequences. Emergency clinicians play an important role in diagnosing and managing STDs and in improving health care outcomes for both the patient and their partners. In addition, antibiotic resistance and emerging infections continue to challenge providers in clinical practice. Read More

Prev Vet Med 2019 May 14;166:86-92. Epub 2019 Mar 14.

Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg, Denmark.

Mycoplasma bovis infections cause disease and production losses in cattle worldwide. The long-term consequences are not well described despite being important for management decisions during and after disease outbreaks. We investigated the association between M. Read More

J Med Microbiol 2019 Apr 1. Epub 2019 Apr 1.

2 Department of Infectious Diseases, Yamagata University Faculty of Medicine, Yamagata 990-9585, Japan.

Purpose: To clarify the spread of Mycoplasma pneumoniae infections in semi-closed settings such as schools and family homes using molecular typing methods.

Methodology: We retrospectively searched for school- and family-based clusters of M. pneumoniae infections based on information regarding patients from whom M. Read More

Am J Case Rep 2019 Mar 29;20:406-411. Epub 2019 Mar 29.

Department of Internal Medicine, King Fahd Hospital of the University, Imam Abdulrahman Bin Faisal University, Al Khobar, Saudi Arabia.

BACKGROUND Mycoplasma hominis, which rarely causes infection after neurosurgical procedures, is a small free-living organism, belonging to the genus Mycoplasma. M. hominis lacks a rigid cell wall and cannot be clearly visualized by routine light microscopy. Read More

Medicine (Baltimore) 2019 Mar;98(13):e15048

Medical Department, The Eighth Affiliated Hospital (Shenzhen Futian), Sun Yat-sen University, Shenzhen, Guangdong, China.

Rationale: Bronchiectasis results when inflammatory and infectious damage to the bronchial and bronchiolar walls leads to a vicious cycle of airway injury. On the basis of the classic characteristic, that is, permanent bronchial dilatation, bronchiectasis is generally considered irreversible in the adult population.

Patient Concerns: A 21-year-old woman presented to our hospital with a 9-day history of productive cough and fever. Read More

J Dtsch Dermatol Ges 2019 Mar;17(3):287-315

WIR "Walk In Ruhr", competence network HIV/AIDS, Center for Sexual Health and Medicine, Department of Dermatology, Venereology and Allergology, Ruhr University, Bochum, Germany.

Worldwide, the incidence of bacterial sexually transmitted infections (STIs) has shown a significant increase in recent years. In Germany, this circumstance is reflected by a rise in the number of reported syphilis cases. There has also been an uptick in the incidence of non-notifiable STIs such as gonorrhea and infections caused by Chlamydia trachomatis and Mycoplasma genitalium. Read More

Obstet Gynecol Sci 2019 Mar 13;62(2):127-133. Epub 2019 Feb 13.

Department of Obstetrics and Gynecology, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, Cheonan, Korea.

Objective: To assess positive culture rate and antimicrobial susceptibilities of (MH) and (UU) in symptomatic general population and pregnant women admitted with preterm labor and premature rupture of membranes.

Methods: We retrospectively reviewed medical records of patients who have undergone culture test and antimicrobial susceptibilities at our center from January 2017 to April 2018. Patients with positive culture for MH, UU, or both were included in this study. Read More

J Clin Microbiol 2019 Mar 27. Epub 2019 Mar 27.

Department of Medical Sciences, Section of Clinical Microbiology and Infectious Diseases, Uppsala University, Uppsala, Sweden.

causes respiratory infections, such as community-acquired pneumonia (CAP), with epidemics recurring every 3-7 years. In 2010-2011, many countries experienced an extraordinary epidemic peak. The cause of these recurring epidemics is not understood, but decreasing herd immunity and shifts in the strains' antigenic properties have been suggested as contributing factors. Read More

Med Mal Infect 2019 Mar 23. Epub 2019 Mar 23.

Infectious and tropical diseases department, Pellegrin hospital, Bordeaux university hospital, 33000 Bordeaux, France; USC EA 3671, Mycoplasma and chlamydia human infections, Bordeaux university, 33000 Bordeaux, France; USC EA 3671, Mycoplasma and chlamydia human infections, French National Institute for Agricultural Research, 33000 Bordeaux, France. Electronic address:

Objectives: Limited data on Mycoplasma genitalium infection has been reported among PrEP users. The aim of this study was to estimate the prevalence and macrolide resistance of M. genitalium infection among enrollees in a French PrEP program. Read More

Eurasian J Med 2019 Feb 30;51(1):5-7. Epub 2018 Nov 30.

Department of Clinical Microbiology and Virology, Polyclinic Tor Vergata Foundation, Rome, Italy.

Objective: To evaluate the performance of the culture colorimetric detection assay MYCO WELL D-ONE (MWD-ONE), designed to detect sexually transmitted infections using real-time polymerase chain reaction (PCR) as a reference method.

Materials And Methods: One hundred and ten urogenital samples were screened for (GV), (TV), (MH), , and (UU)/ (UP) using the MWD-ONE and real-time PCR assays species Real-TM Quant and Anyplex II STI-7 Detection, respectively.

Results: GV was detected in 33 samples by both the MWD-ONE and real-time PCR, while 6 samples gave discordant results. Read More

Br J Cancer 2019 Apr 21;120(8):855-860. Epub 2019 Mar 21.

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

Background: Sexually transmitted infections (STIs) are associated with pelvic inflammatory disease and tubal pathologies. Given the tubal origin of a proportion of ovarian cancers, STIs may be relevant in their aetiology.

Methods: Antibodies indicating past infection with Chlamydia trachomatis, Mycoplasma genitalium, herpes simplex virus type 2, and against human papillomavirus oncogenes (L1 and E6+E7 oncoproteins of types 16, 18, 45) were measured in prediagnosis plasma samples in a nested case-control study in the Nurses' Health Studies (n = 337 cases 1:1 matched to controls). Read More

Ecol Evol 2019 Mar 18;9(5):2516-2534. Epub 2019 Feb 18.

Department of Biology Pennsylvania State University University Park Pennsylvania.

Immune function plays an important role in an animal's defense against infectious disease. In reptiles, immune responses may be complex and counterintuitive, and diagnostic tools used to identify infection, such as induced antibody responses are limited. Recent studies using gene transcription profiling in tortoises have proven useful in identifying immune responses to various intrinsic and extrinsic stressors. Read More

Pathogens 2019 Mar 16;8(1). Epub 2019 Mar 16.

Swine and Poultry Infectious Diseases Research Center and Research Group on Infectious Diseases in Production Animals, Faculty of Veterinary Medicine, University of Montreal, 3200 Sicotte St., Saint-Hyacinthe, QC J2S 2M2, Canada.

and are commonly co-isolated with (primary agent of swine enzootic pneumonia) in gross pneumonia-like lesions, but their involvement in the disease process remains unknown. T cells play an immuno-pathological role during mycoplasmal infections. Dendritic cells (DCs) are major antigen-presenting cells involved in T cell activation and differentiation. Read More

J Cell Physiol 2019 Mar 18. Epub 2019 Mar 18.

Institute for Maternal and Child Health-IRCCS "Burlo Garofolo", Trieste, Italy.

Recently, there are controversial opinions on the presence of Mycoplasmas/Ureaplasmas as colonizers or pathogens, and on the use of a targeted therapy. This study aimed to characterize Mycoplasmas/Ureaplasmas infections in reproductive age women, including the acquisition of sexually transmitted (ST) pathogens and poor birth outcomes. A total of 646 healthy Italian women fulfilled the inclusion criteria including 521 infertile women, 65 pregnant women, and 60 fertile women with identified risk factors and symptomatic for vaginitis/cervicitis. Read More

Emerg Infect Dis 2019 Apr;25(4):719-727

During 2016-2017, we tested asymptomatic men who have sex with men (MSM) in Melbourne, Australia, for Mycoplasma genitalium and macrolide resistance mutations in urine and anorectal swab specimens by using PCR. We compared M. genitalium detection rates for those asymptomatic men to those for MSM with proctitis and nongonococcal urethritis (NGU) over the same period. Read More

Int J Infect Dis 2019 Mar 14;82:86-88. Epub 2019 Mar 14.

Johanniter Hospital, Department of Orthopaedic, General and Accident Surgery, Rheinhausen, Germany.

Judging by the small number of published cases, periprosthetic joint infections (PJI) caused by Mycoplasma species are regarded as unusual. This is not surprising as special growth conditions are necessary for diagnosis and therefore the laboratory must be informed of any clinical suspicion. However, surgeons are generally not aware of the risk factors associated with certain microorganisms causing an infection. Read More

Gynecol Obstet Fertil Senol 2019 Mar 13. Epub 2019 Mar 13.

Infections humaines à mycoplasmes et chlamydiae, USC EA 3671, Institut national de la recherche agronomique, université Bordeaux, 33000 Bordeaux, France; Centre national de référence des infections sexuellement transmissibles bactériennes, CHU de Bordeaux, 33000 Bordeaux, France; Laboratoire de bactériologie, groupe hospitalier Pellegrin, CHU de Bordeaux, 33000 Bordeaux, France.

Objectives: To determine the microorganisms potentially involved in pelvic inflammatory diseases (PIDs) and the different diagnostic methods of PID.

Methods: PubMed and International Guidelines search.

Results: PIDs have various microbial causes. Read More

Enferm Infecc Microbiol Clin 2019 Mar 13. Epub 2019 Mar 13.

Unidad de ITS Vall d'Hebron-Drassanes, Servicio de Enfermedades Infecciosas, Hospital Vall d'Hebron, Barcelona, España.

Sexually transmitted infections caused by Chlamydia trachomatis, including lymphogranuloma venereum and Mycoplasma genitalium have increased in last decade. This epidemiological scenario presents new challenges in order to improve and strengthen our control and prevention strategies. The routine clinical diagnosis of urethritis and cervicitis must be combined with the active search for the causal agent in men with symptoms of dysuria or proctitis, and in women with pelvic inflammatory disease. Read More

Bosn J Basic Med Sci 2019 Mar 17. Epub 2019 Mar 17.

Beijing Key Laboratory for Research on Prevention and Treatment of Tropical Diseases, Beijing Tropical Medicine Research Institute, Beijing Friendship Hospital, Capital Medical University, Beijing, China.

Mycoplasma pneumoniae (M. pneumoniae) is one of the most common causes of community-acquired respiratory tract infections (RTIs). We aimed to investigate the prevalence of M. Read More

Parasitol Res 2019 May 13;118(5):1661-1666. Epub 2019 Mar 13.

Institute of Parasitology, Department of Pathobiology, University of Veterinary Medicine Vienna, Veterinaerplatz 1, 1210, Vienna, Austria.

Canine pathogens transmitted by blood-sucking arthropods are of significant importance for veterinary and, in some cases, human health. However, they are still underestimated and rarely investigated in many parts of the Mediterranean region, mostly due to financial reasons. Therefore, in the present paper, we investigated the occurrence of blood-associated pathogens affecting dogs in Crete, Greece. Read More

BMC Vet Res 2019 Mar 12;15(1):86. Epub 2019 Mar 12.

Anses, Lyon Laboratory, JRU Ruminants Mycoplasmoses, Anses, VetAgro Sup, University of Lyon, Lyon, France.

Background: Several species-specific PCR assays, based on a variety of target genes are currently used in the diagnosis of Mycoplasma bovis infections in cattle herds with respiratory diseases and/or mastitis. With this diversity of methods, and the development of new methods and formats, regular performance comparisons are required to ascertain diagnostic quality. The present study compares PCR methods that are currently used in six national veterinary institutes across Europe. Read More

Int J Gen Med 2019 18;12:101-119. Epub 2019 Feb 18.

Hudson Valley Healing Arts Center, Hyde Park, NY 12538, USA,

Purpose: We collected data from an online survey of 200 of our patients, which evaluated the efficacy of dapsone (diaminodiphenyl sulfone, ie, DDS) combined with other antibiotics and agents that disrupt biofilms for the treatment of chronic Lyme disease/post-treatment Lyme disease syndrome (PTLDS). We also collected aggregate data from direct retrospective chart review, including laboratory testing for Lyme, other infections, and associated tick-borne coinfections. This helped us to determine the frequency of exposure to other infections/coinfections among a cohort of chronically ill Lyme patients, evaluate the efficacy of newer "persister" drug regimens like DDS, and determine how other infections and tick-borne coinfections may be contributing to the burden of chronic illness leading to resistant symptomatology. Read More

Antimicrob Agents Chemother 2019 Mar 11. Epub 2019 Mar 11.

Institut für Medizinische Diagnostik Berlin MVZ, Berlin, Germany.

is a frequent cause of infections of the lower and upper respiratory tract of humans.…. Read More

J Clin Lab Anal 2019 Mar 6:e22879. Epub 2019 Mar 6.

Department of Clinical Medicine, the Third Clinical School of Guangzhou Medical University, Guangzhou, China.

Background: Mycoplasma pneumoniae (M pneumoniae) is a common human etiology of respiratory infections. Nuclear acid sequence-based amplification (NASBA) shows good value for the detection of M pneumoniae that surpasses PCR. However, the optimal detection technology still remains to be identified. Read More

Vet Microbiol 2019 Mar 14;230:273-277. Epub 2019 Feb 14.

Research & Development, Boehringer Ingelheim Animal Health USA, 2412 S. Loop Dr., Ames, IA 50010, USA.

Mycoplasma hyorhinis (Mhr) is a pathogen of pigs causing polyserositis and polyarthritis. The most susceptible population are nursery pigs of approximately 7 weeks of age, although we have shown that clinical signs can persist into finishing aged animals after a late-nursery infection. We have previously demonstrated the efficacy of a novel inactivated Mhr vaccine for the reduction of lameness and polyserositis in caesarian-derived colostrum-deprived (CDCD) pigs vaccinated at 3 weeks and challenged with Mhr at 6 weeks of age. Read More

Cell J 2019 Jul 20;21(2):143-149. Epub 2019 Feb 20.

Department of Molecular Medicine, Pasteur Institute of Iran, Tehran, Iran. Electronic

Objective: spp. is among major contaminants of eukaryotic cell cultures. They cause a wide range of problems associated with cell culture in biology research centers or biotechnological companies. Read More

Ann Biol Clin (Paris) 2019 02;77(1):95-98

Laboratoire de virologie, Institut des agents infectieux (IAI) de Lyon, Centre de biologie et de pathologie Nord, Groupement hospitalier Nord, Centre hospitalier universitaire de Lyon, Lyon, France.

Mycoplasma hominis (MH) and Ureaplasma urealyticum (UU), belonging to mycoplasmas, are implicated in genital and urinary infections. These bacteria are extremely sensitive to environmental factors but remain detectable by culture methods. This study aimed to compare performance of detection on samples performed on eSwab or dry swabs. Read More

Lett Appl Microbiol 2019 May 19;68(5):409-414. Epub 2019 Mar 19.

School of Animal and Veterinary Science, The University of Adelaide, Adelaide, SA, Australia.

The aim of the study was to develop a quantitative real-time PCR assay for diagnosis and monitoring of mycoplasma urinary tract infections (UTI) in a dog. An English Cocker Spaniel dog with the history of urinary tract infection was physically examined and laboratory findings identified chronic renal insufficiency and urinary tract infection. Attempts to culture organisms from pyuric urine failed, and empirical antibiotic therapy did not resolve the pyuria. Read More

MBio 2019 02 19;10(1). Epub 2019 Feb 19.

Nebraska Center for Virology, School of Biological Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska, USA

Nearly all cervical cancers are causally associated with human papillomavirus (HPV). The burden of HPV-associated dysplasias in sub-Saharan Africa is influenced by HIV. To investigate the role of the bacterial microbiome in cervical dysplasia, cytobrush samples were collected directly from cervical lesions of 144 Tanzanian women. Read More

Zhongguo Dang Dai Er Ke Za Zhi 2019 Feb;21(2):150-154

Department of Pediatrics, Lianyungang Maternal and Child Health Care Center Affiliated to Yangzhou University, Lianyungang, Jiangsu 222006, China.

Objective: To study the correlation of galectin-3 level in bronchoalveolar lavage fluid (BALF) with Mycoplasma pneumoniae (MP) load and cellular immunity of neutrophils and macrophages in the airway in children with refractory MP pneumonia (RMPP).

Methods: A total of 64 children with RMPP who were hospitalized from January 2013 to January 2017 were enrolled. In addition to the conservative medical treatment, all the 64 children with RMPP were given bronchoalveolar lavage in the acute stage (5-7 days after admission) and 48 out of the 64 children were given bronchoalveolar lavage in the recovery stage (10-14 days after admission). Read More

Zhongguo Dang Dai Er Ke Za Zhi 2019 Feb;21(2):144-149

Department of Pediatrics, Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.

Objective: To study the features of pathogens in children with lower respiratory tract infection.

Methods: A total of 108 children who were hospitalized due to lower respiratory tract infection and underwent fiber bronchoscopy between January 2017 and June 2018 were enrolled. Bronchoalveolar lavage fluid samples were collected. Read More