242 results match your criteria Mycobacterium Haemophilum


Meningomyeloencephalitis secondary to Mycobacterium haemophilum infection in AIDS.

Acta Neuropathol Commun 2020 May 19;8(1):73. Epub 2020 May 19.

Department of Pathology & Cell Biology, Columbia University Irving Medical Center, New York, NY, 10032, USA.

Infections by opportunistic non-tuberculous mycobacteria (NTM) are rising in global incidence. One emerging, slowly growing NTM is Mycobacterium haemophilum, which can cause skin, lung, bone, and soft tissue infections in immunocompromised patients as well as lymphadenitis in immunocompetent individuals. Detection of this microorganism is difficult using conventional culture-based methods and few reports have documented involvement of this pathogen within the central nervous system (CNS). Read More

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http://dx.doi.org/10.1186/s40478-020-00937-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236527PMC

Mycobacterium haemophilum skin and soft tissue infection in a kidney transplant recipient: A case report and summary of the literature.

Transpl Infect Dis 2020 May 9:e13315. Epub 2020 May 9.

Division of Infectious Diseases, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Non-tuberculous mycobacteria are ubiquitous pathogens causing infections in immunocompromised patients. Here, we describe a kidney transplant recipient who developed skin and soft tissue infection by Mycobacterium haemophilum, complicated by tenosynovitis and fluid collection, following an injury sustained to her right foot. Her immunosuppressant dose was reduced, and she underwent prolonged antimicrobial therapy followed by surgical debridement with a favorable outcome. Read More

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http://dx.doi.org/10.1111/tid.13315DOI Listing

Cutaneous Mycobacterium haemophilum infection: A rare cutaneous manifestation in a patient with Crohn's disease.

Dig Liver Dis 2020 Apr 24. Epub 2020 Apr 24.

School of Medicine, Chung Shan Medical University, Taichung, Taiwan; Endoscopy Center, Changhua Christian Hospital, 500 Nanhsiao Street, Changhua, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.dld.2020.03.018DOI Listing

Review of diseases and health management in zebrafish Danio rerio (Hamilton 1822) in research facilities.

J Fish Dis 2020 Jun 14;43(6):637-650. Epub 2020 Apr 14.

Zebrafish International Resource Center, Eugene, Oregon.

The use of zebrafish (Danio rerio) in biomedical research has expanded at a tremendous rate over the last two decades. Along with increases in laboratories using this model, we are discovering new and important diseases. We review here the important pathogens and diseases based on some 20 years of research and findings from our diagnostic service at the NIH-funded Zebrafish International Resource Center. Read More

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http://dx.doi.org/10.1111/jfd.13165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253333PMC

Disseminated Cutaneous Infection by Mycobacterium haemophilum in a Woman With Systemic Lupus Erythematosus.

J Clin Rheumatol 2020 Apr 2. Epub 2020 Apr 2.

From the Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University.

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http://dx.doi.org/10.1097/RHU.0000000000001365DOI Listing

The Epidemiology of Extrapulmonary Non-tuberculous Mycobacterial Infection in a Pediatric Population.

Pediatr Infect Dis J 2020 Mar 30. Epub 2020 Mar 30.

Gallipoli Medical Research Institute, University of Queensland, Brisbane, Australia.

Background: Nontuberculous mycobacteria (NTM) are ubiquitous in the environment and a well-known cause of lymphadenitis, skin and soft tissue infections. The aim of this study was to evaluate the epidemiology of extrapulmonary pediatric NTM infections occurring from 2000 to 2017 in Queensland, Australia.

Methods: All cases of NTM and TB are notifiable under the Queensland Public Health Act (2005) and associated regulations (2005). Read More

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http://dx.doi.org/10.1097/INF.0000000000002658DOI Listing

Intramedullary spinal cord lesions in an immunocompromised host due to .

IDCases 2020 22;19:e00674. Epub 2019 Nov 22.

University of Colorado School of Medicine 12700 E. 19th Avenue, Mail Stop B168, Aurora, CO 80045, USA.

is a slow growing acid-fast bacillus (AFB) in the nontuberculous mycobacteria (NTM) group. typically causes cervicofacial lymphadenitis in children, cutaneous diseases, septic arthritis and osteomyelitis. However, it rarely causes isolated spinal cord disease. Read More

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http://dx.doi.org/10.1016/j.idcr.2019.e00674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7093745PMC
November 2019

Cutaneous nontuberculous mycobacterial infection in Thailand: A 7-year retrospective review.

Medicine (Baltimore) 2020 Mar;99(10):e19355

Division of Dermatology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

A remarkable increase in the prevalence of cutaneous nontuberculous mycobacterial (NTM) infection has occurred worldwide. However, updated data regarding cutaneous NTM infection in Thailand is limited.This study aim to describe the clinical manifestations, pathogenic organism, and prognostic factors of cutaneous NTM infections among patients living in Thailand. Read More

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http://dx.doi.org/10.1097/MD.0000000000019355DOI Listing

Disseminated cutaneous infection in an immunocompromised Chinese patient presenting with multifocal nodules.

Indian J Dermatol Venereol Leprol 2020 Mar-Apr;86(2):181-184

Department of Dermatovenereology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

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http://dx.doi.org/10.4103/ijdvl.IJDVL_736_17DOI Listing
January 2020

Disseminated Mycobacterium haemophilum With Tenosynovitis in a Liver Transplant Recipient.

J Clin Rheumatol 2019 Dec 24. Epub 2019 Dec 24.

Division of Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, WA.

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http://dx.doi.org/10.1097/RHU.0000000000001232DOI Listing
December 2019

Antiretroviral therapy-induced paradoxical worsening of previously healed Mycobacterium haemophilum cutaneous lesions in advanced HIV infection.

Rev Inst Med Trop Sao Paulo 2019 20;61:e71. Epub 2019 Dec 20.

Fundação Oswaldo Cruz, Laboratório de Biologia Molecular Aplicada a Micobactérias, Rio de Janeiro, Rio de Janeiro, Brazil.

Mycobacterium haemophilum is a nontuberculous mycobacterium that causes localized or disseminated disease, mainly in immunocompromised hosts. We report the case of a 35-year-old HIV-infected woman who presented with several enlarging cutaneous lesions over the arms and legs. Histopathological examination revealed the diagnosis of a cutaneous mycobacterial disease. Read More

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http://dx.doi.org/10.1590/S1678-9946201961071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6922018PMC
February 2020

Cluster of Lymphadenitis due to Nontuberculous Mycobacterium in Children and Adolescents 8-15 Years of Age.

J Korean Med Sci 2019 Dec 2;34(46):e302. Epub 2019 Dec 2.

Department of Pediatrics, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.

Background: Nontuberculous mycobacteria (NTM) lymphadenitis is an under-recognized entity, and data of the true burden in children are limited. Without a high index of suspicion, diagnosis may be delayed and microbiological detection is challenging. Here, we report a cluster of NTM lymphadenitis experienced in Korean children. Read More

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http://dx.doi.org/10.3346/jkms.2019.34.e302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882942PMC
December 2019

Cutaneous Mycobacterium haemophilum infection involving the upper extremities: diagnosis and management guidelines.

Cutis 2019 Oct;104(4):238-241

Southwest Skin Specialists, Phoenix, Arizona, USA.

Mycobacterium haemophilum is a nontuberculous organism that commonly manifests as cutaneous lesions and subcutaneous nodules in immunosuppressed adults. Because M haemophilum infection is rare, the epidemiology, reservoir, and mode of transmission remain largely unknown. Infection presents a challenge to the dermatology community because it is infrequently suspected and commonly misidentified, resulting in delayed diagnosis. Read More

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October 2019

Rare infection in patient with rheumatoid arthritis treated with adalimumab.

BMJ Case Rep 2019 Nov 21;12(11). Epub 2019 Nov 21.

Internal Medicine, Rush University, Chicago, Illinois, USA.

is a rare pathogen, predominately present in the immunocompromised population. It is especially studied in HIV and haematological malignancy patients. Given its unique living conditions, it is often difficult to establish its diagnosis, but it is often suspected by its classic association with ulcerating skin findings. Read More

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http://dx.doi.org/10.1136/bcr-2019-230871DOI Listing
November 2019

Mycobacterium haemophilum: a challenging treatment dilemma in an immunocompromised patient.

Cutis 2019 Sep;104(3):E7-E10

Department of Medicine, Division of Infectious Diseases, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

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September 2019

Clinical Characteristics and Treatment Outcomes for Patients Infected with Mycobacterium haemophilum.

Emerg Infect Dis 2019 09;25(9):1648-1652

Mycobacterium haemophilum is a nontuberculous mycobacterium that can infect immunocompromised patients. Because of special conditions required for its culture, this bacterium is rarely reported and there are scarce data for long-term outcomes. We conducted a retrospective study at Siriraj Hospital, Bangkok, Thailand, during January 2012-September 2017. Read More

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http://dx.doi.org/10.3201/eid2509.190430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711220PMC
September 2019
4 Reads

Clinical manifestations and outcomes of musculoskeletal nontuberculous mycobacterial infections.

Rheumatol Int 2019 Oct 27;39(10):1783-1787. Epub 2019 Jul 27.

Division of Rheumatology, Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkok Noi, Bangkok, 10700, Thailand.

To investigate the clinical manifestations and outcomes of musculoskeletal (MSK) nontuberculous mycobacterium (NTM) infections. This study was a retrospective cohort study using the Siriraj Hospital database from 2005 to 2017. Enrolled were all patients aged 15 or older who had an MSK infection with NTM identified in synovial fluid, pus, or tissue by an acid-fast bacilli stain, culture, or polymerase chain reaction. Read More

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http://dx.doi.org/10.1007/s00296-019-04392-8DOI Listing
October 2019
2 Reads

Failure among Patients with Non-Tuberculous Mycobacterial Infections in Skin, Soft Tissue, and Musculoskeletal System in Southern Taiwan, 2012-2015.

Surg Infect (Larchmt) 2019 Sep 8;20(6):492-498. Epub 2019 May 8.

2School of Medicine, National Yang-Ming University, Taipei, Taiwan, Republic of China.

The incidence of non-tuberculous mycobacterial (NTM) infections of the skin, soft tissue, and musculoskeletal system (SSTI) has increased over the past two decades, however, relatively few studies have documented the reasons for the reported increase. Specifically, no standardized treatment protocols have been adopted, therefore, clinical prognosis of the patients with NTM SSTI has thus far remained uncertain. In our study, we sought to identify risk factors for treatment failure in southern Taiwan. Read More

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https://www.liebertpub.com/doi/10.1089/sur.2018.314
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http://dx.doi.org/10.1089/sur.2018.314DOI Listing
September 2019
12 Reads

Case of Mycobacterium haemophilum infection presenting with Sweet's syndrome-like reactions.

J Dermatol 2019 09 2;46(9):e319-e320. Epub 2019 Apr 2.

Dermatology Department of Integrated Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.

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http://dx.doi.org/10.1111/1346-8138.14864DOI Listing
September 2019
15 Reads

Discrimination of and in Clinical Isolates and Specimens by Multiplex PCR Assay and Prediction of Drug Susceptibility.

J Clin Microbiol 2019 02 30;57(2). Epub 2019 Jan 30.

Department of Mycobacteriology, Leprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan

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http://dx.doi.org/10.1128/JCM.01760-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355549PMC
February 2019
4 Reads

Cutaneous Mycobacterial Infections.

Clin Microbiol Rev 2018 01 14;32(1). Epub 2018 Nov 14.

Servicio de Dermatología y Departamento de Micología, Hospital General de México, Mexico City, Mexico.

Humans encounter mycobacterial species due to their ubiquity in different environmental niches. In many individuals, pathogenic mycobacterial species may breach our first-line barrier defenses of the innate immune system and modulate the activation of phagocytes to cause disease of the respiratory tract or the skin and soft tissues, sometimes resulting in disseminated infection. Cutaneous mycobacterial infections may cause a wide range of clinical manifestations, which are divided into four main disease categories: (i) cutaneous manifestations of infection, (ii) Buruli ulcer caused by and other related slowly growing mycobacteria, (iii) leprosy caused by and , and (iv) cutaneous infections caused by rapidly growing mycobacteria. Read More

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http://dx.doi.org/10.1128/CMR.00069-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302357PMC
January 2018
17 Reads

Cutaneous Infection With Mycobacterium haemophilum in an Immunocompromised Patient.

Iran J Kidney Dis 2018 Oct;12(5):312-314

Infectious Diseases and Tropical Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Mycobacterium haemophilum is a fastidious nontuberculosis Mycobacterium that must be considered in the differential diagnosis of infections in immunocompromised patients. Mycobacterium haemophilum typically is a pathogen of the cutaneous or subcutaneous tissue and also presents as septic arthritis, osteomyelitis, pulmonary disease, and lymphadenitis. We report a 32-year-old man with past medical history of kidney transplantation, endocarditis, gastrointestinal bleeding, and hypertension, complaining of multiple painful nodular lesions since 3 months earlier. Read More

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October 2018
46 Reads

Overview of a Disease Outbreak and Introduction of a Step-by-Step Protocol for the Eradication of Mycobacterium haemophilum in a Zebrafish System.

Zebrafish 2019 02 24;16(1):77-86. Epub 2018 Oct 24.

1 Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom.

In 2017, the zebrafish unit at University of Glasgow experienced a detrimental outbreak of pathogenic bacterium, Mycobacterium haemophilum. The presence of other bacterial species was also confirmed by bacteriology growth in the same unit. The affected individuals composed of a wild-origin parental population sourced from India and their F1 offspring generation. Read More

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https://www.liebertpub.com/doi/10.1089/zeb.2018.1628
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http://dx.doi.org/10.1089/zeb.2018.1628DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357262PMC
February 2019
7 Reads

Highly Reduced Genome of the New Species , the Causative Agent of Nodular Thelitis and Tuberculoid Scrotitis in Livestock and a Close Relative of the Leprosy Bacilli.

mSphere 2018 10 3;3(5). Epub 2018 Oct 3.

Institut des Agent infectieux, Hôpital de la Croix Rousse, Hospices Civils de Lyon, Lyon, France

Nodular thelitis is a chronic enzootic infection affecting dairy cows and goats. The causative agent was recently shown to be related to the leprosy-causing bacilli and In this study, the genome of this pathogen was sequenced and analyzed. Phylogenomic analyses confirmed that the pathogen present in nodular thelitis and tuberculoid scrotitis is a distinct species related to the leprosy bacilli and Because the pathogen was originally isolated from a bovine udder, it was named "" The genome of "" is only 3. Read More

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http://msphere.asm.org/lookup/doi/10.1128/mSphere.00405-18
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http://dx.doi.org/10.1128/mSphere.00405-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170788PMC
October 2018
22 Reads

Mycobacterium haemophilum infection in a renal transplant patient with inflammatory bowel disease.

Dermatol Online J 2017 Sep 15;23(9). Epub 2017 Sep 15.

University of Massachusetts Medical School, Worcester, Massachusetts.

A 61-year-old immunosuppressed renal transplant patient with inflammatory bowel disease presented with tender pink nodules on the trunk and extremities. An initial biopsy was suggestive of metastatic Crohn disease, but after disease persistence, a second biopsy revealed disseminated Mycobacterium haemophilum. Atypical mycobacterial infections should be considered in immunosuppressed patients. Read More

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September 2017
11 Reads

Late-onset postoperative Mycobacterium haemophilum endophthalmitis masquerading as inflammatory uveitis: a case report.

BMC Infect Dis 2018 02 7;18(1):70. Epub 2018 Feb 7.

Department of Ophthalmology, Faculty of Medicine, Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkok Noi, Bangkok, 10700, Thailand.

Background: Although atypical mycobacteria had been increasingly found in various ocular infections in the past decades, a slow-growing Mycobacterium haemophilum (M. haemophilum) was scarcely reported. Similar to tuberculous infection, the presentation can masquerade as low-grade granulomatous intraocular inflammation with partial response to corticosteroids. Read More

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http://dx.doi.org/10.1186/s12879-018-2985-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804003PMC
February 2018
15 Reads

Environmental Screening of Aeromonas hydrophila, Mycobacterium spp., and Pseudocapillaria tomentosa in Zebrafish Systems.

J Vis Exp 2017 12 8(130). Epub 2017 Dec 8.

Biological Research Facility, The Francis Crick Institute.

Health monitoring systems are developed and used in zebrafish research facilities because pathogens of Danio rerio such as Aeromonas hydrophila, Mycobacterium spp., and Pseudocapillaria tomentosa have the potential to impair animal welfare and research. The fish are typically analyzed post mortem to detect microbes. Read More

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https://www.jove.com/video/55306/environmental-screening-aer
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http://dx.doi.org/10.3791/55306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755534PMC
December 2017
23 Reads

Closing the Brief Case: Disseminated Mycobacterium haemophilum Infection in a Kidney Transplant Recipient.

J Clin Microbiol 2018 01 26;56(1). Epub 2017 Dec 26.

Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York, USA

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http://dx.doi.org/10.1128/JCM.00562-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744199PMC
January 2018
12 Reads

The Brief Case: Disseminated Mycobacterium haemophilum Infection in a Kidney Transplant Recipient.

J Clin Microbiol 2018 01 26;56(1). Epub 2017 Dec 26.

Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York, USA

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http://dx.doi.org/10.1128/JCM.00561-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744214PMC
January 2018
12 Reads

Nontubercular Mycobacterial Infection in a Renal Allograft Recipient.

Authors:
U Anandh K Jayanna

Indian J Nephrol 2017 Nov-Dec;27(6):478-481

Department of Nephrology, Yashoda Hospitals, Secunderabad, Telangana, India.

A 71-year-old male, a renal allograft recipient, presented to us with a history of fever and right palm swelling. He had a history of fever 7 years back when he was treated with antitubercular treatment (ATT). Three years back, he was diagnosed to have gout and he was started on allopurinol. Read More

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http://dx.doi.org/10.4103/ijn.IJN_336_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704418PMC
December 2017
3 Reads

Mycobacterium haemophilum osteomyelitis in the immunocompromised host.

Pediatr Int 2017 Dec 4;59(12):1279-1281. Epub 2017 Dec 4.

Department of Pediatrics, Osaka University Graduate School of Medicine, Osaka, Japan.

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http://dx.doi.org/10.1111/ped.13426DOI Listing
December 2017
6 Reads

[A toddler with a red swelling in the neck].

Ned Tijdschr Geneeskd 2017 ;161:D1613

AMC, afd. MKA-chirurgie, Amsterdam.

Background: The differential diagnosis in a child with a swelling in the neck is broad. Chronic lymphadenopathy in children quite often leads to extensive blood tests. Cervicofacial non-tuberculous mycobacterial (NTM) lymphadenitis is, however, not revealed by blood tests. Read More

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June 2018
6 Reads

Case of Mycobacterium haemophilum misdiagnosed as Mycobacterium intracellulare due to one base insertion in the bacterial genome.

J Dermatol 2018 Jan 3;45(1):64-66. Epub 2017 Aug 3.

Dermatology, Department of Internal Related, Faculty of Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.

Mycobacterium haemophilum is a slow-growing, non-tuberculous mycobacteria that causes cutaneous infection. We describe a case of cutaneous infection in a 68-year-old Japanese man with polymyositis. This was caused by M. Read More

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http://dx.doi.org/10.1111/1346-8138.13988DOI Listing
January 2018
45 Reads

Fifteen-year clinical experience with at the Mayo Clinic: A case series.

J Clin Tuberc Other Mycobact Dis 2017 Aug 28;8:26-32. Epub 2017 Jun 28.

Division of Infectious Diseases, Mayo Clinic, 200 First St., Rochester, MN 55905, United States.

is an uncommonly encountered acid-fast staining bacillus (AFB) that can cause a broad range of infections. We describe a tertiary care center's experience with infections identified from 2000 to 2015. Ten adult patients were identified with infections, and most had immunocompromising conditions. Read More

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http://dx.doi.org/10.1016/j.jctube.2017.06.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850245PMC

HIV and mycobacteria.

Authors:
Gary W Procop

Semin Diagn Pathol 2017 Jul 12;34(4):332-339. Epub 2017 Apr 12.

Staff, Pathology and Clinical Microbiology, Cleveland Clinic, 9500 Euclid Avenue/LL2-2, Cleveland, OH 44195, United States. Electronic address:

The importance of mycobacteria as opportunistic pathogens, particularly members of the M. avium complex (MAC), in patients with progressive HIV infection was recognized early in the AIDS epidemic. It took longer to appreciate the global impact and devastation that would result from the deadly synergy that exists between HIV and M. Read More

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http://dx.doi.org/10.1053/j.semdp.2017.04.006DOI Listing
July 2017
18 Reads

Development of Quantitative Real-Time PCR Assays for Postmortem Detection of spp. Common in Zebrafish () Research Colonies.

J Am Assoc Lab Anim Sci 2017 Mar;56(2):131-141

Department of Biomedical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis, Oregon, Veterinary Diagnostic Laboratory, College of Veterinary Medicine, Oregon State University, Corvallis, Oregon;, Email:

Mycobacterium spp. infections are common in zebrafish kept in research facilities. These comorbidities can substantially modulate the responses of these fish to external and internal stimuli. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361037PMC
March 2017
23 Reads

Mycobacterium haemophilum: A report of cutaneous Infection in a Patient with end-stage renal disease.

Int J Mycobacteriol 2016 Dec 9;5 Suppl 1:S236. Epub 2016 Nov 9.

Pediatric Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address:

Introduction: Mycobacterium haemophilum is a slow-growing nontuberculous mycobacterium (NTM) that can cause ulcerating cutaneous or subcutaneous nodular skin lesions in immunocompromised and immunocompetent patients. Acid-fast staining cannot distinguish NTM from M. tuberculosis; culturing at two temperatures with iron-supplemented media and polymerase chain reaction (PCR) are needed for optimal detection of M. Read More

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http://dx.doi.org/10.1016/j.ijmyco.2016.09.024DOI Listing
December 2016
19 Reads

Other Slow-Growing Nontuberculous Mycobacteria.

Microbiol Spectr 2016 11;4(6)

Infectious Diseases Section, VA Medical Center, Omaha, NE 68105.

The list of clinically important slow-growing nontuberculous mycobacteria (NTM) continues to expand as new species are identified and older ones are found to be pathogenic. Based on pigment production, the strains may be classified as photochromogenic, scotochromogenic, or unpigmented. Some of these organisms are not newly discovered but have heretofore been considered virtually nonpathogenic. Read More

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http://dx.doi.org/10.1128/microbiolspec.TNMI7-0012-2016DOI Listing
November 2016
13 Reads

Disseminated Mycobacterium haemophilum infection in a renal transplant recipient.

BMJ Case Rep 2016 Oct 31;2016. Epub 2016 Oct 31.

Medical Clinic, University Hospital Hamburg-Eppendorf, Hamburg, Germany.

Opportunistic infections are a major concern in renal and transplant medicine. We present the case of a renal transplant recipient with a generalised Mycobacterium haemophilum infection after an increase in immunosuppressive therapy and treatment with a tumour necrosis factor-α (TNF-α) inhibitor. Infection involved skin and soft tissue, joints and bones, as well as the renal transplant with an interstitial nephritis. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2016-21604
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http://dx.doi.org/10.1136/bcr-2016-216042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093746PMC
October 2016
10 Reads

Successful management of Mycobacterium haemophilum lower extremity cutaneous infection in a matched-unrelated donor stem cell transplant recipient.

Transpl Infect Dis 2017 Feb 16;19(1). Epub 2016 Dec 16.

Department of Pharmacy, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.

Nontuberculous mycobacterial infections can often occur in individuals with adequate immune function. Such infections typically have cutaneous involvement and are caused by rapidly growing mycobacterium. Other nontuberculous mycobacteria species, like Mycobacterium haemophilum, almost always present as opportunistic infections occurring in severely immunocompromised hosts. Read More

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http://dx.doi.org/10.1111/tid.12627DOI Listing
February 2017
6 Reads

16S-23S Internal Transcribed Spacer Region PCR and Sequencer-Based Capillary Gel Electrophoresis has Potential as an Alternative to High Performance Liquid Chromatography for Identification of Slowly Growing Nontuberculous Mycobacteria.

PLoS One 2016 17;11(10):e0164138. Epub 2016 Oct 17.

Centre for Infectious Diseases and Microbiology Laboratory Services, ICPMR - Pathology West, Westmead Hospital, Westmead, NSW, Australia.

Accurate identification of slowly growing nontuberculous mycobacteria (SG-NTM) of clinical significance remains problematic. This study evaluated a novel method of SG-NTM identification by amplification of the mycobacterial 16S-23S rRNA internal transcribed spacer (ITS) region followed by resolution of amplified fragments by sequencer-based capillary gel electrophoresis (SCGE). Fourteen American Type Culture Collection (ATCC) strains and 103 clinical/environmental isolates (total n = 24 species) of SG-NTM were included. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0164138PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066948PMC
May 2017
10 Reads

Mycobacterium haemophilum infection in a juvenile leatherback sea turtle (Dermochelys coriacea).

J Vet Diagn Invest 2016 Nov 3;28(6):718-721. Epub 2016 Oct 3.

Departments of Small Animal Clinical Sciences (Donnelly, Wellehan), University of Florida, College of Veterinary Medicine, Gainesville, FLInfection Diseases and Pathology (Waltzek), University of Florida, College of Veterinary Medicine, Gainesville, FLLarge Animal Clinical Sciences (NI Stacy), University of Florida, College of Veterinary Medicine, Gainesville, FLGumbo Limbo Nature Center, Boca Raton, FL (Chadam)National Marine Fisheries Service, Office of Protected Resources at University of Florida, Gainesville, FL (BA Stacy)

Mycobacteriosis is infrequently reported in free-ranging sea turtles. Nontuberculous Mycobacterium haemophilum was identified as the causative agent of disseminated mycobacteriosis in a juvenile leatherback turtle (Dermochelys coriacea) that was found stranded on the Atlantic coast of Florida. Disseminated granulomatous inflammation was identified histologically, most notably affecting the nervous system. Read More

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http://dx.doi.org/10.1177/1040638716661746DOI Listing
November 2016
20 Reads

Three-Dimensional Screen: A Comprehensive Approach to the Health Monitoring of Zebrafish.

Zebrafish 2016 07 16;13 Suppl 1:S132-7. Epub 2016 May 16.

Mill Hill Laboratory, The Francis Crick Institute , London, United Kingdom .

Considering the numbers of zebrafish held in the laboratories, it is relevant to develop some tools to monitor the health of the animals, as well as their biotope. Environmental samples can be used to detect aquatic pathogens. Comprehensive health monitoring would thus seek pathogens in three dimensions of the animals and microbes' habitat: the fish, the sludge, and the water. Read More

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http://dx.doi.org/10.1089/zeb.2015.1200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931732PMC
July 2016
6 Reads

A 45-year-old man with sarcoidosis, fever and skin lesions.

Acta Reumatol Port 2015 Oct-Dec;40(4):388-9

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May 2018
4 Reads

Facial Skin Lesions in Children Caused by Nontuberculous Mycobacteria.

Pediatr Dermatol 2016 Mar-Apr;33(2):196-9. Epub 2016 Jan 29.

Department of Oral and Maxillofacial Surgery, Amstelland Hospital Amstelveen and Academic Medical Center, Amsterdam, The Netherlands.

Background: Nontuberculous mycobacteria rarely cause facial skin lesions in immunocompetent children.

Aim: I describe the clinical features and treatment of nontuberculous mycobacteria facial lesions.

Materials And Methods: The diagnosis of a facial nontuberculous mycobacteria infection was established using polymerase chain reaction. Read More

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http://dx.doi.org/10.1111/pde.12755DOI Listing
January 2017
8 Reads

The Complete Genome Sequence of the Emerging Pathogen Mycobacterium haemophilum Explains Its Unique Culture Requirements.

mBio 2015 Nov 17;6(6):e01313-15. Epub 2015 Nov 17.

Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA Howard Hughes Medical Institute, Albert Einstein College of Medicine, Bronx, New York, USA

Unlabelled: Mycobacterium haemophilum is an emerging pathogen associated with a variety of clinical syndromes, most commonly skin infections in immunocompromised individuals. M. haemophilum exhibits a unique requirement for iron supplementation to support its growth in culture, but the basis for this property and how it may shape pathogenesis is unclear. Read More

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http://mbio.asm.org/content/6/6/e01313-15.full.pdf
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http://mbio.asm.org/cgi/doi/10.1128/mBio.01313-15
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http://dx.doi.org/10.1128/mBio.01313-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659460PMC
November 2015
54 Reads

Disseminated Mycobacterium haemophilum skeletal disease in a patient with interferon-gamma deficiency.

Intern Med J 2015 Oct;45(10):1073-6

Department of Infectious Diseases, Box Hill Hospital, Eastern Health, Melbourne, Victoria, Australia.

Disseminated non-tuberculous mycobacterial (NTM) infection is rare in immunocompetent adults. Anti-interferon-gamma (IFN-γ) autoantibodies have recently been associated with NTM infections, particularly in patients of Asian ethnicity. We describe a case of disseminated Mycobacterium haemophilum skeletal infection due to anti IFN-γ autoantibodies in a 71-year-old Cambodian man. Read More

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http://doi.wiley.com/10.1111/imj.12875
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http://dx.doi.org/10.1111/imj.12875DOI Listing
October 2015
10 Reads

Two Episodes of Cutaneous Non-Tuberculous Mycobacterial Infection in a Patient with Psoriasis.

Dermatol Reports 2015 May 15;7(2):5712. Epub 2015 Jun 15.

Department of Dermatology, National Skin Centre , Singapore.

Non-tuberculous mycobacteria (NTM) are a group of environmental pathogens, which cause a broad spectrum of disease. The incidence of NTM infection is increasing, especially in immunocompromized patients. The past three decades also saw a rapid increase in the incidence of NTM infection involving otherwise healthy subjects. Read More

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http://www.pagepress.org/journals/index.php/dr/article/view/
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http://dx.doi.org/10.4081/dr.2015.5712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500867PMC
May 2015
14 Reads