1,456 results match your criteria Mycobacterium Chelonae

Invasive Outbreak at a Pediatric Dental Clinic.

Open Forum Infect Dis 2021 Jun 15;8(6):ofab165. Epub 2021 Apr 15.

Disease Control and Epidemiology, Orange County Health Care Agency, Santa Ana, California, USA.

Background: species, specifically and (MABs), are known to contaminate water systems and are uncommon causes of health care-associated infection, but morbidity can be significant and treatment complex.

Methods: Odontogenic MAB infections occurred in patients following pulpotomy procedures at dental clinic A from 1 January to 6 September 2016. We identified confirmed and probable cases using culture data, imaging, pathology results, and surgical findings. Read More

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Increased whiB7 expression and antibiotic resistance in Mycobacterium chelonae carrying two prophages.

BMC Microbiol 2021 Jun 9;21(1):176. Epub 2021 Jun 9.

Department of Molecular and Biomedical Sciences, University of Maine, Orono, ME, United States.

Background: The global rise in the incidence of non-tuberculosis mycobacterial infections is of increasing concern due their high levels of intrinsic antibiotic resistance. Although integrated viral genomes, called prophage, are linked to increased antibiotic resistance in some bacterial species, we know little of their role in mycobacterial drug resistance.

Results: We present here for the first time, evidence of increased antibiotic resistance and expression of intrinsic antibiotic resistance genes in a strain of Mycobacterium chelonae carrying prophage. Read More

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Combining comparative genomic analysis with machine learning reveals some promising diagnostic markers to identify five common pathogenic non-tuberculous mycobacteria.

Microb Biotechnol 2021 May 21. Epub 2021 May 21.

CAS Key Laboratory of Genome Sciences & Information, China National Center for Bioinformation, Chinese Academy of Sciences, Beijing Institute of Genomics, Beijing, 100101, China.

Non-tuberculous mycobacteria (NTM) can cause various respiratory diseases and even death in severe cases, and its incidence has increased rapidly worldwide. To date, it's difficult to use routine diagnostic methods and strain identification to precisely diagnose various types of NTM infections. We combined systematic comparative genomics with machine learning to select new diagnostic markers for precisely identifying five common pathogenic NTMs (Mycobacterium kansasii, Mycobacterium avium, Mycobacterium intracellular, Mycobacterium chelonae, Mycobacterium abscessus). Read More

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Investigation of two cases of Mycobacterium chelonae infection in haemato-oncology patients using whole genome sequencing and a potential link to the hospital water supply.

J Hosp Infect 2021 May 1. Epub 2021 May 1.

Scottish Mycobacteria Reference Laboratory, Royal Infirmary of Edinburgh.

Background: Haemato-oncology patients are at increased risk of infection from atypical mycobacteria such as Mycobacterium chelonae which are commonly found in both domestic and hospital water systems.

Aims: To describe the investigation and control measures following two patient cases of M. chelonae and positive water samples in our hospital. Read More

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Heater-Cooler Devices and Risk of Contamination during Cardiac Surgery.

Thorac Cardiovasc Surg 2021 Apr 21. Epub 2021 Apr 21.

Department of Cardiothoracic Surgery, Jena University Hospital, Friedrich-Schiller University of Jena, Jena, Germany.

Background:  Heater-cooler devices (HCD) have been implicated in a cardiosurgical contamination scenario causing prosthetic valve endocarditis.

Aim:  We characterized contamination of new HCDs and assessed the risk of intraoperative microorganism transmission from the HCD to the operating field.

Methods:  We initially acquired four new FlexTherm and then four new Maquet HCU40 HCDs and assessed occurrence and speed of microbial contamination (including mycobacteria) assessing swab and water samples from the device. Read More

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A case of infantile exogenous lipoid pneumonia with an unusual complication managed by modified whole lung lavage.

Sudan J Paediatr 2021 ;21(1):82-88

Pediatric Pulmonary Section, Pediatric Department, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.

Exogenous lipoid pneumonia (ELP) is a known complication of lipid administration through either the nasal or oral route. ELP in paediatric patients is usually managed by discontinuing lipid administration and supportive care, including respiratory support and the use of antibiotics for secondary bacterial infection. The other modalities that remain controversial include the use of corticosteroids and clearing lipids by whole lung lavage. Read More

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January 2021

General characteristics, features of cultivation and antibiotic resistance representatives of mycobacterium fortuitum group representatives (review of literature).

Klin Lab Diagn 2021 Apr;66(4):223-228

Samara State Medical University.

Recently, more and more scientific works have been devoted to non-tuberculous mycobacteria, both by domestic and foreign researchers. One of the main reasons for this is the increase in patients with immunosuppression of various origins, improvement of the quality of laboratory and instrumental diagnostics of mycobacteriosis. This article focuses on the representatives of the M. Read More

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Mycobacteria In Skin Lesions and the Habitat of the Endangered Houston Toad (Anaxyrus houstonensis).

J Wildl Dis 2021 Apr 15. Epub 2021 Apr 15.

Texas State University, Department of Biology, 601 University Drive, San Marcos, Texas 78666, USA.

Head-starting of the federally endangered Houston toad (Anaxyrus houstonensis), that is, the release of egg strands, tadpoles, and metamorphic juveniles produced in captivity into the original breeding ponds, requires assessment of potential threats for the transmission of pathogens from captive to free-ranging toads. We used Illumina-based 16S rRNA V3 amplicon sequencing to investigate the community structure of bacteria from skin lesions of captive Houston toad and habitat (pond) samples. Proteobacteria, alone or together with Actinobacteria and, in some samples, Cyanobacteria represented virtually all reads in tissue lesion samples, whereas pond samples were much more diverse, with Acidobacteria, Actinobacteria, Bacteriodetes, Chloroflexi, Cyanobacteria, Firmicutes, Planctomycetes, Proteobacteria, and Verrucomicrobia present with little variation between samples. Read More

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Comparison of Susceptibility of Delafloxacin with Ciprofloxacin, Moxifloxacin, and Other Comparator Antimicrobials against Isolates of Nontuberculous Mycobacteria.

Antimicrob Agents Chemother 2021 Jun 17;65(7):e0007921. Epub 2021 Jun 17.

The University of Texas Health Science Center at Tyler, Mycobacteria/Nocardia Laboratory, Tyler, Texas, USA.

Nontuberculous mycobacterial (NTM) infections are increasing globally. Mycobacterium avium complex (MAC) and M. abscessus complex are the most commonly reported NTM. Read More

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Mycobacterium salmoniphilum and M. chelonae in Captive Populations of Chinook Salmon.

J Aquat Anim Health 2021 Jun 29;33(2):107-115. Epub 2021 Mar 29.

Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, 2108 Tupper Hall, Davis, California, 95616-5270, USA.

Chinook Salmon Oncorhynchus tshawytscha is a keystone fish species in the Pacific Northwest. In 2019, unusual mortalities occurred in two different populations of cultured fingerlings from the same facility in California, USA. The systems consist of outdoor, enclosed, flow-through freshwater tanks that are maintained at 18 ± 1°C. Read More

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Epidemiological risk factors and the geographical distribution of eight Mycobacterium species.

Maura J Donohue

BMC Infect Dis 2021 Mar 12;21(1):258. Epub 2021 Mar 12.

United States Environmental Protection Agency, Office of Research and Development, Center of Environmental Solutions and Emergency Response (CESER), 26 W. Martin Luther King Dr. Mail Stop 587, Cincinnati, OH, 45268, USA.

Background: Nontuberculous mycobacteria (NTM) are environmental bacterium that may cause and/or compound respiratory diseases in humans. There are over a hundred NTM species with varying pathogenicity's Therefore, it is necessary to characterize the populations at risk for each species.

Methods: Demographic (age, sex, and state of residence) and microbiological data from 2014 were extracted from Mississippi, Missouri, and Ohio disease surveillance systems. Read More

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Rapid identification of non-tuberculous mycobacteria with MALDI-TOF mass spectrometry.

Infez Med 2021 Mar;29(1):79-84

Microbiology Unit, ASST Papa Giovanni XXIII, Bergamo, Italy.

Rapid and accurate identification of non-tuberculous mycobacteria (NTM) is important for a prompt start to antibiotic therapy. The aim of this study was to obtain accurate identification of NTM quickly by analyzing the performance of the MALDI-TOF mass spectrometry (MS) system VITEK® MS in identifying various NTM species from solid medium and MGIT 960 liquid medium. The study was performed in two phases: preliminary and perspective. Read More

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Genitourinary non-tuberculous mycobacterial (GU-NTM) infections: A single institution experience in South India.

Indian J Tuberc 2021 Jan 26;68(1):65-72. Epub 2020 Aug 26.

Former Senior Resident, Department of Urology, Amrita Institute of Medical Sciences and Research Centre, Amrita Vishwa Vidyapeetham (Amrita University), Ponekkara, Cochin, Kerala, 682041, India.

Introduction: Non-tuberculous mycobacterial (NTM) infections are rarely reported, and more so with genitourinary infections. This retrospective study was designed to understand the proportion and behaviour of genitourinary non-tuberculous mycobacterial (GU-NTM) infections compared with genitourinary mycobacterial tuberculosis (GU-MTB) treated at a tertiary care hospital in South India.

Materials And Methods: The hospital records of every bacteriologically proved GU-MTB and GU-NTM infections treated at this centre from 2010 to 2016 were retrospectively reviewed. Read More

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January 2021

Catheter-related blood stream infection caused by in a child with myeloid leukemia associated with Down syndrome.

Clin Case Rep 2021 Feb 18;9(2):835-840. Epub 2020 Dec 18.

Department of Pediatrics Kobe University Graduate School of Medicine Kobe Japan.

Rapidly growing nontuberculous mycobacteria should be considered if GPRs gram-positive rods are detected in blood cultures 2-3 days after the blood sample collection. Read More

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February 2021

Scleral Buckle Infection Caused by : A Case Report.

Int Med Case Rep J 2021 5;14:51-53. Epub 2021 Feb 5.

Department of Ophthalmology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.

A 63-year-old female with a history of retinal detachment repair with scleral buckle from 28 years prior presented with exposure of the buckle in her right eye. After removing the buckle and anchoring sutures, the operation field was washed with 0.25% polyvinyl alcohol-iodine, vancomycin, and ceftazidime. Read More

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February 2021

Isolation and identification of nontuberculous mycobacteria from specimens of lower respiratory tract of transplanted patients based on the evaluation of 16SrRNA gene.

Ann Ig 2021 Mar-Apr;33(2):189-197

Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

Background: Nontuberculous mycobacteria are pervasive microorganisms and are often present as saprophytes in humans, animals, and the environment. Today, these bacteria are known as the most important environmental opportunists and, in the last decades, infections by nontuberculous mycobacteria have multiplied, due to increased immunodeficiency (cancer, transplant recipients, HIV).

Study Design: This study aimed to investigate the infections by nontuberculous mycobacteria in transplanted patients. Read More

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February 2021

[Lung disease by Mycobacterium chelonae in an immunocompetent patient successfully treated with linezolid].

Rev Peru Med Exp Salud Publica 2020 Oct-Dec;37(4):785-787. Epub 2021 Feb 3.

Universidad Nacional de Ucayali, Pucallpa, Perú.

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Cutaneous Coinfection of Cytomegalovirus and Accelerated by Immunosuppression.

Case Rep Pathol 2021 29;2021:8819560. Epub 2021 Jan 29.

Department of Diagnostic Pathology, Shimada Municipal Hospital, Shimada, Shizuoka, Japan.

A mildly diabetic 58-year-old male had traumatic ulceration on the left popliteal fossa, and the lesion progressed to a painful 6 cm deep ulcer. After surgical debridement and skin grafting, ulceration recurred. Pyoderma gangrenosum was clinically diagnosed after the first biopsy, indicating a noninfective ulcer. Read More

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January 2021

Polymicrobial Extensor Tenosynovitis Including Mycobacterium chelonae Caused by a Dog Bite: A Case Report.

JBJS Case Connect 2021 Feb 4;11(1):e20.00608. Epub 2021 Feb 4.

Department of Orthopaedic Surgery, Kitasato University School of Medicine, Sagamihara-shi, Kanagawa, Japan.

Case: A nonimmunocompromised 77-year-old man was bitten in the hand by his dog; redness, swelling, and exudate developed. Despite debridement and medications administered at another hospital, his symptoms did not improve. He was referred to us after 3 months. Read More

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February 2021

Species diversity and molecular analysis of opportunistic Mycobacterium, Nocardia and Rhodococcus isolated from the hospital environment in a developing country, a potential resources for nosocomial infection.

Genes Environ 2021 Jan 28;43(1). Epub 2021 Jan 28.

Department of Basic and Laboratory and Sciences, Khomein University of Medical Sciences, Qods street, Khomein, Iran.

Background: Hospital environmental resources have a significant role in cross-transmission of opportunistic pathogens such as actinomycetes species to the patients. Actinomycetes have a remarkable capability to survive in adverse and harsh conditions of hospital environments; therefore, they are a threat to the health of patients. Due to this issue, we aimed to determine the frequency and diversity of actinomycetes species in hospital soil, water and dust by using a combination of conventional and molecular methods including the phenotypic and biochemical tests for preliminary identification and the PCR amplification of the specific region of the 16S rRNA, hsp65 gene and sequence analyses of 16S rRNA for the genus and species identification. Read More

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January 2021

Postoperative Mycobacterium chelonae Infection Mimicking A Granulomatous Suture Reaction.

Dermatol Surg 2021 Jun;47(6):840-841

Division of Dermatology, University of California, Los Angeles, CA.

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A case of relapsed pulmonary infection presenting with severe weight loss and treated with a combination of antibiotic therapy and percutaneous feeding.

C Pease G G Alvarez

J Clin Tuberc Other Mycobact Dis 2021 Feb 26;22:100209. Epub 2020 Dec 26.

Ottawa Hospital, Department of Medicine, Ottawa, Canada.

is a type of nontuberculous mycobacteria most commonly associated with skin and soft tissue infections. We present a case of recurrent pulmonary infection presenting with severe weight loss. After recurrence, sputum cultures remained positive for 2 years despite appropriate antibiotics. Read More

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February 2021

A Complication of Mycobacterium chelonae Infection Following Orbital Floor Fracture Repair.

J Craniofac Surg 2021 Jun;32(4):1494-1495

Department of Otolaryngology - Head and Neck Surgery, Division of Facial Plastic and Reconstructive Surgery.

Abstract: Mycobacterium chelonae is a rare, atypical nontuberculous bacterium that has been reported to be an underlying cause of persistent wound infections. Although there are several studies highlighting the role of M chelonae as the putative cause of other postoperative wound infections, to our knowledge there are no reports of infection following implant placement for repair of an orbital floor fracture. The authors present a unique case describing the management of a persistent postoperative infection in a young, immunocompetent patient with an orbital floor fracture repaired with a Stryker Medpor Titan implant. Read More

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Occurrence of spp. in ornamental fish.

Ann Agric Environ Med 2020 Dec 9;27(4):535-539. Epub 2019 Dec 9.

Department of Fish Diseases and Biology, Faculty of Veterinary Medicine, University of Life Sciences, Lublin, Poland.

Introduction And Objective: Fish mycobacteriosis is a chronic granulomatous disease caused by several species of bacteria from the genus , described as nontuberculous mycobacteria (NTM). The most important species causing fish mycobacterioses are , and . Mycobacteria infecting fish also include zoonotic pathogens. Read More

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December 2020

Susceptibility Testing of Omadacycline against Nontuberculous Mycobacteria.

Antimicrob Agents Chemother 2021 02 17;65(3). Epub 2021 Feb 17.

Mycobacteria/Nocardia Laboratory, University of Texas Health Science Center at Tyler, Tyler, Texas, USA.

Infections caused by nontuberculous mycobacteria (NTM) are increasing globally. complex (MAC) and complex are the most frequently encountered NTM, and oral treatment options are extremely limited for these pathogens, especially for the complex. In this study, the potency of omadacycline, a new tetracycline derivative, was tested against 111 isolates of NTM. Read More

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February 2021

The effect of culture media dilution on recovery of rapidly growing mycobacteria.

New Microbiol 2020 Oct;43(4):191-194

National Clinical Laboratory on Tuberculosis, Beijing Key laboratory on Drug-resistant Tuberculosis Research, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tum.

Nontuberculous mycobacteria (NTM) are important environmental opportunistic pathogens of human and animals. Rapidly growing mycobacteria (RGM) are important emerging pathogens causing NTM infections. Unfortunately, the majority of microorganisms in the environment resist cultivation in the laboratory. Read More

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October 2020

Challenges in Treating Prosthetic Joint Infection.

J Pharm Pract 2020 Dec 7:897190020977757. Epub 2020 Dec 7.

20814Howard University Hospital, Washington, DC, USA.

Prosthetic joint infections (PJIs) remain a major complication of arthroplasty, most of which are caused by and gram-negative bacteria. Unfortunately, cultures are false negative in upward of 7 percent of patients with suspected PJIs, and commonly in infections caused by rare rapidly growing mycobacterium (RGM) species. Guidelines recommend 6 months of antimycobacterial therapy for bone diseases caused by RGM, with empiric therapy consists of an oral macrolide (clarithromycin or azithromycin) plus tobramycin and imipenem-cilastatin. Read More

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December 2020

Profile of Nontuberculous Mycobacteria in Patients Suspected of Tuberculosis and Drug-Resistant Tuberculosis.

J Lab Physicians 2020 Dec 23;12(3):203-211. Epub 2020 Nov 23.

Department of Microbiology, SMS Medical College, Jaipur, Rajasthan, India.

 Infections due to nontuberculous mycobacteria (NTM) is increasing globally and may present as drug-resistant tuberculosis (DRTB). In India, data on NTM prevalence and species diversity is limited. Present study was conducted to detect the prevalence and profile of NTM among patients suspected of DRTB using paraffin slide culture (PSC)and mycobacteria growth indicator tube (MGIT) culture methods for isolation of NTM. Read More

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December 2020

Recurrent Skin Infection Unmasked as Factitious Disorder Using Bacterial Whole Genome Sequence Analysis.

Open Forum Infect Dis 2020 Nov 22;7(11):ofaa506. Epub 2020 Oct 22.

Division of Pediatric Infectious Disease, Department of Pediatrics, University of Bern, Bern, Switzerland.

infections usually resolve with adequate therapy. We report the case of an adolescent with a chronic and progressive infection refractory to combined antimicrobial and surgical therapy. Whole genome sequence analysis of consecutive isolates distinguished reinfection from recurrence and contributed to the diagnosis of a factitious disorder. Read More

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November 2020

Investigating hospital Mycobacterium chelonae infection using whole genome sequencing and hybrid assembly.

PLoS One 2020 9;15(11):e0236533. Epub 2020 Nov 9.

Department of Microbiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America.

Mycobacterium chelonae is a rapidly growing nontuberculous mycobacterium that is a common cause of nosocomial infections. Here we describe investigation of a possible nosocomial transmission of M. chelonae at the Hospital of the University of Pennsylvania (HUP). Read More

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December 2020