1,337 results match your criteria Mycobacterium Chelonae


Donor-Related Nontuberculous Mycobacterial Interface Infection After Descemet Membrane Endothelial Keratoplasty.

Cornea 2019 Feb 7. Epub 2019 Feb 7.

Department of Ophthalmology, University Hospitals Leuven, Leuven, Belgium.

Purpose: To describe the first reported case of Mycobacterium chelonae-related interface keratitis after Descemet membrane endothelial keratoplasty (DMEK), successfully treated with DMEK exchange.

Methods: A case of donor-related DMEK interface keratitis, treated with medical therapy and DMEK exchange, was studied retrospectively.

Results: A patient with Fuchs endothelial dystrophy developed infectious interface keratitis after DMEK. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001895DOI Listing
February 2019

New onset erythematous nodules in an elderly woman.

Dermatol Online J 2018 Aug 15;24(8). Epub 2018 Aug 15.

Harvard Medical School, Boston, Massachusetts.

An 86-year- old woman with a history of recurrent bronchitis and giant cell arteritis presented for new onset, cyclic and migratory erythematous nodules associated with fatigue and weight loss. Although a systemic vasculitis was initially suspected, elevated inflammatory markers and symptoms persisted despite aggressive corticosteroid therapy. Excisional biopsy of one nodule showed dense suppurative and granulomatous inflammation that was rife with acid-fast bacilli. Read More

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August 2018
3 Reads

synergism of rifabutin with clarithromycin, imipenem and tigecycline against the complex.

Antimicrob Agents Chemother 2019 Jan 22. Epub 2019 Jan 22.

Department of Internal Medicine, National Taiwan University Hospital, No. 7 Chung-Shan South Road, Taipei, Taiwan.

Infections caused by the difficult-to-treat are increasing in frequency. Rifabutin, in contrast to rifampin, appears to be active against , especially against clarithromycin-resistant strains. However, exploring for potential synergy between rifabutin and available antimicrobials is currently limited. Read More

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http://dx.doi.org/10.1128/AAC.02234-18DOI Listing
January 2019

Rapid emergence of cryptococcal fungemia, Mycobacterium chelonae vertebral osteomyelitis and gastro intestinal stromal tumor in a young HIV late presenter: a case report.

BMC Infect Dis 2018 Dec 27;18(1):693. Epub 2018 Dec 27.

Division of Infectious Diseases, Department of Clinical and Experimental Medicine, ARNAS Garibaldi Hospital, University of Catania, Catania, Italy.

Background: Highly active antiretroviral therapy has significantly changed the natural history of HIV infection, leading to a dramatic reduction of HIV-related morbidity and mortality. Late Presenters, Very Late Presenters and AIDS presenters still represent, also in Europe, including Italy, a huge challenge in terms of diagnostic and therapeutic management.

Case Presentation: A 35-year-old male with a history of fever and back pain. Read More

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http://dx.doi.org/10.1186/s12879-018-3573-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307234PMC
December 2018
4 Reads

Medical Tourism and Postoperative Infections: A Systematic Literature Review of Causative Organisms and Empiric Treatment.

Plast Reconstr Surg 2018 Dec;142(6):1644-1651

Galveston, Texas From the Division of Plastic Surgery, Department of Surgery, University of Texas Medical Branch.

Background: Medical tourism has become increasingly globalized as individuals travel abroad to receive medical care. Cosmetic patients in particular are more likely to seek surgery abroad to defray costs. Unfortunately, not all procedures performed abroad adhere to strict hygienic regulations, and bacterial flora vary. Read More

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http://dx.doi.org/10.1097/PRS.0000000000005014DOI Listing
December 2018
1 Read

Outbreak of Tattoo-Associated Nontuberculous Mycobacterial Skin Infections.

Clin Infect Dis 2018 Nov 17. Epub 2018 Nov 17.

Florida Department of Health in Miami-Dade County, Epidemiology, Disease Control, and Immunization Services, Miami, FL, USA.

Background: On April 29, 2015, the Florida Department of Health in Miami-Dade County (DOH-Miami-Dade) was notified by a local dermatologist of three patients with suspect nontuberculous mycobacterial (NTM) infection after receiving tattoos at a local tattoo studio.

Methods: DOH-Miami-Dade conducted interviews and offered testing, described below, to tattoo studio clients reporting rashes. Culture of clinical isolates and identification were performed at the Florida Bureau of Public Health Laboratories (BPHL). Read More

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http://dx.doi.org/10.1093/cid/ciy979DOI Listing
November 2018
2 Reads

Antimicrobial susceptibility testing of Mycobacteroides (Mycobacterium) abscessus complex, Mycolicibacterium (Mycobacterium) fortuitum, and Mycobacteroides (Mycobacterium) chelonae.

J Infect Chemother 2019 Feb 14;25(2):117-123. Epub 2018 Nov 14.

Department of Mycobacterium Reference and Research, The Research Institute of Tuberculosis, Japan Anti-tuberculosis Association, Kiyose, Japan; Basic Mycobacteriosis, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.

The drug susceptibility of rapidly growing mycobacteria (RGM) varies among isolates. Treatment strategies similarly differ depending on the isolate, and for some, no clear strategy has been identified. This complicates clinical management of RGM. Read More

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http://dx.doi.org/10.1016/j.jiac.2018.10.010DOI Listing
February 2019
1 Read
1.384 Impact Factor

Disseminated Cutaneous Infection in a Patient with Dermatomyositis.

Skinmed 2018 9;16(5):343-345. Epub 2018 Nov 9.

University of Central Florida College of Medicine, Orlando, FL.

A 39-year-old Caucasian man with a history of dermatomyositis and diabetes mellitus on a regimen of tacrolimus and methylprednisolone presented to our dermatology outpatient clinic with a painful eruption on his left lower leg. Three months before presentation, he had been admitted to the hospital for cellulitis of the left leg. During admission, a needle aspirate of the left leg cellulitis was performed to obtain fluid for culture to guide therapy. Read More

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November 2018
3 Reads

A description of Mycobacterium chelonae subsp. gwanakae subsp. nov., a rapidly growing mycobacterium with a smooth colony phenotype due to glycopeptidolipids.

Int J Syst Evol Microbiol 2018 Dec 12;68(12):3772-3780. Epub 2018 Oct 12.

1​Department of Biomedical Sciences, Microbiology and Immunology, Cancer Research Institute, Institute of Endemic Diseases, and Liver Research Institute, Seoul National University Medical Research Center (SNUMRC), Seoul National University College of Medicine, Seoul, Republic of Korea.

Three rapidly growing mycobacterial strains, MOTTH4W, MOTT36W and MOTT68W, were isolated from the sputa of three independent Korean patients co-infected with Mycobacterium yongonense Type II strains. The 16S rRNA gene sequences of all three strains were unique, which were closest to that of Mycobacterium chelonae subsp. bovis KCTC 39630 (99. Read More

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http://www.microbiologyresearch.org/content/journal/ijsem/10
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http://dx.doi.org/10.1099/ijsem.0.003056DOI Listing
December 2018
21 Reads
2.511 Impact Factor

MmpL8 controls virulence and production of a previously unknown glycolipid family.

Proc Natl Acad Sci U S A 2018 10 9;115(43):E10147-E10156. Epub 2018 Oct 9.

Université de Versailles Saint Quentin en Yvelines, INSERM UMR1173, 78000 Versailles, France;

is a peculiar rapid-growing (RGM) capable of surviving within eukaryotic cells thanks to an arsenal of virulence genes also found in slow-growing mycobacteria (SGM), such as A screen based on the intracellular survival in amoebae and macrophages (MΦ) of an transposon mutant library revealed the important role of MAB_0855, a yet uncharacterized Mycobacterial membrane protein Large (MmpL). Large-scale comparisons with SGM and RGM genomes uncovered MmpL12 proteins as putative orthologs of MAB_0855 and a locus-scale synteny between the and loci. A KO mutant of the gene, designated herein as , had impaired adhesion to MΦ and displayed a decreased intracellular viability. Read More

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http://www.pnas.org/lookup/doi/10.1073/pnas.1812984115
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http://dx.doi.org/10.1073/pnas.1812984115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205491PMC
October 2018
4 Reads

Successful Treatment of a Renal Abscess Caused by : A Case Report.

Open Forum Infect Dis 2018 Sep 16;5(9):ofy196. Epub 2018 Aug 16.

Division of Infectious Diseases, Cleveland Clinic Akron General, Akron, Ohio.

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http://dx.doi.org/10.1093/ofid/ofy196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119465PMC
September 2018

Ibrutinib Therapy and Skin and Soft Tissue Infection.

Open Forum Infect Dis 2018 Jul 18;5(7):ofy168. Epub 2018 Jul 18.

Infectious Diseases Section, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio.

Ibrutinib is an irreversible inhibitor of Bruton's tyrosine kinase approved for the treatment of B-cell malignancies. There is growing concern about the risk of opportunistic infections following ibrutinib therapy. Herein, we describe the first case of skin and soft tissue infection in a patient receiving ibrutinib and recount the challenges in treating this infection. Read More

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http://dx.doi.org/10.1093/ofid/ofy168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065501PMC
July 2018
16 Reads

Cutaneous Mycobacterium chelonae infection in a patient with rheumatoid arthritis treated with glucocorticoids.

Joint Bone Spine 2019 Jan 30;86(1):105. Epub 2018 Jun 30.

Department of rheumatology, North hospital, university hospital of Saint-Étienne, avenue Albert-Raimond, 42270 Saint-Priest-en-Jarez, France; SAINBIOSE, Inserm U1059, university of Lyon, 42023 Saint-Étienne, France; CIC Inserm U1408, university of Lyon, 42023 Saint-Étienne, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S1297319X183012
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http://dx.doi.org/10.1016/j.jbspin.2018.06.004DOI Listing
January 2019
8 Reads

Necrotizing osteomyelitis in a man with disseminated infection.

IDCases 2018 21;12:71-73. Epub 2018 Mar 21.

Division of Mycobacterial and Infectious Diseases, Department of Medicine, National Jewish Health, Denver, CO, USA.

Cases of disseminated nontuberculous mycobacterial (NTM) infection are difficult to treat. We encountered an elderly man with disseminated infection. The clinical evaluation and treatment of patients with this type of systemic infection pose unique challenges. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22142509183005
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http://dx.doi.org/10.1016/j.idcr.2018.03.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010973PMC
March 2018
1 Read

Cutaneous Mycobacterium chelonae infection following autologous peripheral blood stem cell transplantation for POEMS syndrome.

J Infect Chemother 2018 Dec 31;24(12):983-986. Epub 2018 May 31.

Department of Hematology, Tottori Prefectural Central Hospital, Tottori, Japan.

Although hematopoietic stem cell transplantation (HSCT) may increase the curability of refractory hematologic diseases, it requires complication management due to a long-term immunocompromised state. We experienced a case who received an autologous peripheral blood stem cell transplantation (Auto-PBSCT) for POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes) and developed cutaneous Mycobacterium chelonae infection. It is clear that attention needs to be paid to prevent bacterial, fungal and viral infection after HSCT. Read More

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http://dx.doi.org/10.1016/j.jiac.2018.05.004DOI Listing
December 2018
4 Reads

First United States Outbreak of Mycobacterium abscessus Hand and Foot Disease Among Children Associated With a Wading Pool.

J Pediatric Infect Dis Soc 2018 May 29. Epub 2018 May 29.

Idaho Division of Public Health, Boise.

Background: Mycobacterium abscessus, an emerging pathogen in healthcare settings, has rarely been associated with community outbreaks. During February-May 2013, Idaho public health officials and pediatric infectious disease physicians investigated an outbreak of M abscessus skin infections in children whose only common exposure was an indoor wading pool.

Methods: Healthcare providers and parents reported possible M abscessus cases. Read More

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https://academic.oup.com/jpids/advance-article/doi/10.1093/j
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http://dx.doi.org/10.1093/jpids/piy036DOI Listing
May 2018
3 Reads

A cluster of nontuberculous mycobacterial endophthalmitis (NTME) cases after cataract surgery: clinical features and treatment outcomes.

Eye (Lond) 2018 09 29;32(9):1504-1511. Epub 2018 May 29.

Department of Ophthalmology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.

Purpose: To report the clinical features and treatment outcomes in a cluster of patients with endophthalmitis after cataract surgery caused by nontuberculous mycobacterium.

Patients And Methods: Retrospective chart review and noncomparative, consecutive case series. Nine consecutive cases of endophthalmitis, after cataract surgery in a local clinic, were referred to our hospital. Read More

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http://dx.doi.org/10.1038/s41433-018-0108-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137041PMC
September 2018
26 Reads

Bloodstream infection caused by Mycobacterium chelonae.

Pediatr Int 2018 Jun 28;60(6):599-600. Epub 2018 May 28.

Division of Clinical Laboratory Medicine, Kanazawa University, Kanazawa, Japan.

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http://doi.wiley.com/10.1111/ped.13553
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http://dx.doi.org/10.1111/ped.13553DOI Listing
June 2018
1 Read

Multi-drug resistant scleral buckle infection.

Am J Ophthalmol Case Rep 2018 Jun 5;10:276-278. Epub 2018 Apr 5.

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, FL, USA.

Purpose: To describe a case of Multi-drug resistant scleral buckle infection.

Observations: A 56 year-old male with history of retinal detachment repair with scleral buckle 20 years prior presented with 8 months of intermittent pain and redness in the left eye. The patient was diagnosed with scleral buckle infection, the buckle was removed, and cultures revealed multi-drug resistant The postoperative course included orbital cellulitis treated with systemic linezolid, clarithromycin, and imipenem. Read More

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http://dx.doi.org/10.1016/j.ajoc.2018.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956710PMC
June 2018
3 Reads

Cutaneous Nontuberculous Mycobacterial Infections in Alberta, Canada: An Epidemiologic Study and Review.

J Cutan Med Surg 2018 Sep/Oct;22(5):479-483. Epub 2018 May 17.

3 Division of Diagnostic and Applied Microbiology, Department of Laboratory Medicine and Pathology, University of Alberta and the Alberta Provincial Public Health Laboratory, WC Mackenzie Health Sciences Centre, Edmonton, AB, Canada.

Background: Cutaneous infections caused by nontuberculous mycobacteria (NTM) occur infrequently. Nonetheless, the incidence of NTM infections is reported to be increasing. In Canada, cutaneous NTM infections have not been well described. Read More

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http://dx.doi.org/10.1177/1203475418776945DOI Listing
December 2018
16 Reads

Non-tuberculous Mycobacterium species causing mycobacteriosis in farmed aquatic animals of South Africa.

BMC Microbiol 2018 04 13;18(1):32. Epub 2018 Apr 13.

Tuberculosis Laboratory, Agricultural Research Council - Onderstepoort Veterinary Research, Onderstepoort, South Africa.

Background: Mycobacteriosis caused by non-tuberculous mycobacteria (NTM), is among the most chronic diseases of aquatic animals. In addition, fish mycobacteriosis has substantial economic consequences especially in the aquaculture and fisheries industry as infections may significantly decrease production and trade. Some fish NTM pathogens are highly virulent and zoonotic; as such, infection of aquaria with these pathogens is a public health concern. Read More

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https://bmcmicrobiol.biomedcentral.com/articles/10.1186/s128
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http://dx.doi.org/10.1186/s12866-018-1177-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899368PMC
April 2018
11 Reads

Increasing nontuberculous mycobacteria reporting rates and species diversity identified in clinical laboratory reports.

Authors:
Maura J Donohue

BMC Infect Dis 2018 04 10;18(1):163. Epub 2018 Apr 10.

United States Environmental Protection Agency, 26 W. Martin Luther King Dr. Mail Stop 587, Cincinnati, Ohio, 45268, USA.

Background: Nontuberculous Mycobacteria (NTM) are environmental microorganisms that can affect human health. A 2009-2010 occurrence survey of NTM in potable tap water samples indicated an increased recovery rate for many clinically significant species such as M. avium (30%) and M. Read More

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http://dx.doi.org/10.1186/s12879-018-3043-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891905PMC
April 2018
4 Reads

Exit Site Infection due to Mycobacterium chelonae in an Elderly Patient on Peritoneal Dialysis.

Case Rep Nephrol Dial 2018 Jan-Apr;8(1):1-9. Epub 2018 Jan 19.

aDivision of Nephrology and Rheumatology, Department of Internal Medicine, Kariya Toyota General Hospital, Kariya, Japan.

Nontuberculous mycobacteria (NTM) are rarely isolated from peritoneal dialysis (PD)-associated catheter infections. However, NTM infection is usually difficult to treat and leads to catheter loss. Prompt diagnosis is essential for appropriate treatment. Read More

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http://dx.doi.org/10.1159/000486159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836155PMC
January 2018
1 Read

Non-Tuberculous Mycobacterial Infections Related to Peritoneal Dialysis.

Perit Dial Int 2018 Mar-Apr;38(2):147-149

Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, School of Medicine, Keio University, Tokyo, Japan.

Most infections related to peritoneal dialysis (PD) are caused by common bacteria, and non-tuberculous mycobacteria are rare. The clinical characteristics and prognosis of PD patients with non-tuberculous mycobacterial infections were investigated at our hospital. Non-tuberculous mycobacteria were detected in 11 patients (exit-site infection, tunnel infection, and peritonitis in 3, 5, and 3 patients, respectively). Read More

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http://www.pdiconnect.com/lookup/doi/10.3747/pdi.2017.00172
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http://dx.doi.org/10.3747/pdi.2017.00172DOI Listing
December 2018
14 Reads

osteomyelitis presenting as a mycobacterial spindle cell pseudotumor.

Int J Mycobacteriol 2018 Jan-Mar;7(1):104-106

Department of Histopathology, Nuffield Orthopaedic Centre, Oxford, England, UK.

We report a case of an 88-year-old man with osteomyelitis of the right ankle, with histopathology demonstrating a Mycobacterium spindle cell pseudotumor. The Mycobacterium contained in this spindle cell pseudotumor was Mycobacterium chelonae. M. Read More

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http://www.ijmyco.org/text.asp?2018/7/1/104/226775
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http://dx.doi.org/10.4103/ijmy.ijmy_166_17DOI Listing
March 2018
6 Reads

Phylogenomics and Comparative Genomic Studies Robustly Support Division of the Genus into an Emended Genus and Four Novel Genera.

Front Microbiol 2018 13;9:67. Epub 2018 Feb 13.

Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, CA, Canada.

The genus contains 188 species including several major human pathogens as well as numerous other environmental species. We report here comprehensive phylogenomics and comparative genomic analyses on 150 genomes of species to understand their interrelationships. Phylogenetic trees were constructed for the 150 species based on 1941 core proteins for the genus , 136 core proteins for the phylum Actinobacteria and 8 other conserved proteins. Read More

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http://dx.doi.org/10.3389/fmicb.2018.00067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819568PMC
February 2018
1 Read

Clinical features of infection caused by non-tuberculous mycobacteria: 7 years' experience.

Infection 2018 Jun 23;46(3):357-363. Epub 2018 Feb 23.

Department of Biomedical Sciences, University of Sassari, Sassari, Italy.

Introduction: Non-tuberculous mycobacteria (NTM) are ubiquitous organisms associated with various infections. The aim of the study was to determine the most relevant clinical characteristics of NTM during the 7-year period.

Methodology: A retrospective study of NTM infections was conducted between January 2009 and December 2016. Read More

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http://dx.doi.org/10.1007/s15010-018-1128-2DOI Listing
June 2018
16 Reads

.

BMJ Case Rep 2018 Feb 22;2018. Epub 2018 Feb 22.

Department of Internal Medicine, Michigan State University, Lansing, Michigan, USA.

is a rapidly growing mycobacterium which is known to respond well to standard antibiotic treatment regimen. There are no specific guidelines for treatment. Antibiotics are chosen based on the bacterial sensitivity. Read More

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http://dx.doi.org/10.1136/bcr-2017-222569DOI Listing
February 2018
12 Reads

Cutaneous infection due to Mycobacterium immunogenum: an European case report and review of the literature.

Dermatol Online J 2017 Oct 15;23(10). Epub 2017 Oct 15.

Department of Dermatology, Hospital Universitario Fundacion Alcorcon, Madrid, Spain.

(no more than 200 words): In the last few years, the incidence of cutaneous infections caused by nontuberculous mycobacteria is increasing. Since Mycobacterium immunogenum was first described in 2001, few case reports have been described, all of them in the American continent. We report a case with cutaneous infection caused by this newly discovered NTB in Europe. Read More

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October 2017
16 Reads

A High-Throughput Approach for Identification of Nontuberculous Mycobacteria in Drinking Water Reveals Relationship between Water Age and .

MBio 2018 02 13;9(1). Epub 2018 Feb 13.

Department of Civil & Environmental Engineering, University of Michigan, Ann Arbor, Michigan, USA

Nontuberculous mycobacteria (NTM) frequently detected in drinking water (DW) include species associated with human infections, as well as species rarely linked to disease. Methods for improved the recovery of NTM DNA and high-throughput identification of NTM are needed for risk assessment of NTM infection through DW exposure. In this study, different methods of recovering bacterial DNA from DW were compared, revealing that a phenol-chloroform DNA extraction method yielded two to four times as much total DNA and eight times as much NTM DNA as two commercial DNA extraction kits. Read More

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http://dx.doi.org/10.1128/mBio.02354-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821076PMC
February 2018
4 Reads

Nontuberculous mycobacterium infection in renal transplant recipients: a systematic review.

Infect Dis (Lond) 2018 06 5;50(6):409-416. Epub 2018 Feb 5.

a Kidney Disease Center , The First Affiliated Hospital, College of Medicine, Zhejiang University , Hangzhou , PR China.

Background: Nontuberculous mycobacterium (NTM) infections are important complications in renal transplant recipients.

Methods: Cases of NTM diseases post-renal transplantation published in English were identified in the PubMed database. The clinical and laboratory characteristics of these cases were reviewed. Read More

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http://dx.doi.org/10.1080/23744235.2017.1411604DOI Listing
June 2018
1 Read

Mycobacteremia from Crushed Hydromorphone Tablet Injection.

Cureus 2017 Nov 27;9(11):e1883. Epub 2017 Nov 27.

Internal Medicine, St. Joseph Mercy Oakland.

Mycobacterium abscessus is a fast growing, non-tubercular mycobacterium (NTM) found in water. NTM bacteremia is usually seen in immunocompromised patients who have intravascular catheters. Mycobacterium abscessus bacteremia is often caused by exposure to contaminated water supply in hemodialysis units. Read More

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https://www.cureus.com/articles/9523-mycobacteremia-from-cru
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http://dx.doi.org/10.7759/cureus.1883DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786344PMC
November 2017
5 Reads

Survival of Bacterial and Parasitic Pathogens from Zebrafish (Danio rerio) After Cryopreservation and Thawing.

Zebrafish 2018 04 25;15(2):188-201. Epub 2018 Jan 25.

1 Department of Microbiology, Oregon State University , Corvallis, Oregon.

Cryopreservation is a common method used to preserve the sperm of various animal species, and it is widely used with zebrafish (Danio rerio). As with other animals, there is a possibility of paternal pathogen transmission through sperm. We evaluated the ability of five common and important pathogens of zebrafish to survive cryopreservation as used with zebrafish sperm and freezing without cryopreservant. Read More

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http://www.liebertpub.com/doi/10.1089/zeb.2017.1528
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http://dx.doi.org/10.1089/zeb.2017.1528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878546PMC
April 2018
15 Reads

Activities of Dual Combinations of Antibiotics Against Multidrug-Resistant Nontuberculous Mycobacteria Recovered from Patients with Cystic Fibrosis.

Microb Drug Resist 2018 Oct 25;24(8):1191-1197. Epub 2018 Jan 25.

1 Department of Pathology, The Johns Hopkins School of Medicine , Baltimore, Maryland.

Patients with cystic fibrosis (CF) are at risk for recurrent pulmonary infections due to increased viscosity of airway secretions, leading to persistent colonization with pathogenic bacteria, including nontuberculous mycobacteria (NTM). Extensive antibiotic use for treatment of infections has led to increasing antimicrobial resistance, which is a significant barrier to the treatment of NTMs. We examined the in vitro activity of several antibiotics against a selection of the most drug-resistant clinical isolates of Mycobacterium abscessus, Mycobacterium chelonae, and Mycobacterium avium complex recovered from CF patients at our institution, as well as paired combinations of antibiotics against a subset of M. Read More

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https://www.liebertpub.com/doi/10.1089/mdr.2017.0286
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http://dx.doi.org/10.1089/mdr.2017.0286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200022PMC
October 2018
4 Reads

Mycobacterium abscessus infections in lung transplant recipients: 15-year experience from a single institution.

Transpl Infect Dis 2018 Apr 12;20(2):e12835. Epub 2018 Feb 12.

Department of Cardiothoracic Surgery, Mayo Clinic, Jacksonville, FL, USA.

Purpose: To evaluate our institutional experience with Mycobacterium abscessus infections occurring in lung transplant recipients (LTR).

Methods: We retrospectively reviewed our prospectively collected institutional adult lung transplant database from 2001 to 2015 to identify patients with M. abscessus or Mycobacterium chelonae/abscessus infection before or after transplantation. Read More

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http://doi.wiley.com/10.1111/tid.12835
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http://dx.doi.org/10.1111/tid.12835DOI Listing
April 2018
8 Reads

Amplification of Hsp 65 gene and usage of restriction endonuclease for identification of non tuberculous rapid grower mycobacterium.

Indian J Tuberc 2018 Jan 29;65(1):57-62. Epub 2017 Sep 29.

Department of Microbiology, National Institute of Tuberculosis and Respiratory Diseases, Sri Aurobindo Marg, New Delhi 110030, India.

Background: The rapid grower mycobacteria have emerged as significant group of human pathogen amongst the Runyon group IV organisms that are capable of causing infection in both the healthy and immunocompromised hosts. Study aimed to identification of species amongst rapid grower non tuberculous mycobacterial isolates by polymerase chain reaction - restriction enzyme analysis (PRA). Analysis and comparison of results with standard biochemical tests. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00195707163037
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http://dx.doi.org/10.1016/j.ijtb.2017.08.030DOI Listing
January 2018
7 Reads

Response to Comment on Mycobacterium chelonae Infection of the Buttocks Secondary to Lipofilling: A Case Report and Review of the Literature.

Aesthetic Plast Surg 2018 04 9;42(2):611-612. Epub 2018 Jan 9.

Department of Plastic Reconstructive Surgery, University of Miami, 1400 NW 12th Ave Suite 200, Miami, FL, 33136, USA.

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http://link.springer.com/10.1007/s00266-017-1042-5
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http://dx.doi.org/10.1007/s00266-017-1042-5DOI Listing
April 2018
5 Reads

Opportunistic infections in patients with idiopathic inflammatory myopathies.

Int J Rheum Dis 2018 Feb 5;21(2):487-496. Epub 2018 Jan 5.

Internal Medicine Department, Autonomous University of Barcelona, Barcelona, Spain.

Aim: To describe the prevalence, clinical characteristics and risk factors of opportunistic infection (OI) in a cohort of patients with inflammatory myopathies, and compare mortality rates between those with and without OIs.

Methods: In total, 204 patients from our myositis cohort were reviewed to identify patients who had experienced an OI during the period 1986-2014. The patients' clinical characteristics, treatments received, and outcomes were systematically recorded. Read More

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http://dx.doi.org/10.1111/1756-185X.13255DOI Listing
February 2018
38 Reads

Environmental Screening of Aeromonas hydrophila, Mycobacterium spp., and Pseudocapillaria tomentosa in Zebrafish Systems.

J Vis Exp 2017 12 8(130). Epub 2017 Dec 8.

Biological Research Facility, The Francis Crick Institute.

Health monitoring systems are developed and used in zebrafish research facilities because pathogens of Danio rerio such as Aeromonas hydrophila, Mycobacterium spp., and Pseudocapillaria tomentosa have the potential to impair animal welfare and research. The fish are typically analyzed post mortem to detect microbes. Read More

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https://www.jove.com/video/55306/environmental-screening-aer
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http://dx.doi.org/10.3791/55306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755534PMC
December 2017
12 Reads

[A rare complication of a permanent tattoo].

Presse Med 2018 Jan 20;47(1):94-95. Epub 2017 Dec 20.

CHU Ambroise-Paré, service de dermatologie générale et oncologique, 9, avenue Charles-de-Gaulle, 92104 Boulogne cedex, France.

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http://dx.doi.org/10.1016/j.lpm.2017.10.013DOI Listing
January 2018
4 Reads

Cyclophostin and Cyclipostins analogues, new promising molecules to treat mycobacterial-related diseases.

Int J Antimicrob Agents 2018 Apr 11;51(4):651-654. Epub 2017 Dec 11.

Aix-Marseille Univ., CNRS, LISM, IMMFR3479, Marseille, France. Electronic address:

The progression of mycobacterial diseases requires the development of new therapeutics. This study evaluated the efficacy and selectivity of a panel of Cyclophostin and Cyclipostins analogues (CyCs) against various bacteria and mycobacteria. The activity 26 CyCs was first assayed by the agar plate method. Read More

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http://dx.doi.org/10.1016/j.ijantimicag.2017.12.001DOI Listing
April 2018
53 Reads

First insights into a type II toxin-antitoxin system from the clinical isolate Mycobacterium sp. MHSD3, similar to epsilon/zeta systems.

PLoS One 2017 13;12(12):e0189459. Epub 2017 Dec 13.

Microbiologia, Departament de Biologia, Universitat de les Illes Balears, Palma de Mallorca, Spain.

A putative type II toxin-antitoxin (TA) system was found in the clinical isolate Mycobacterium sp. MHSD3, a strain closely related to Mycobacterium chelonae. Further analyses of the protein sequences of the two genes revealed the presence of domains related to a TA system. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0189459PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728571PMC
January 2018
4 Reads

Bilateral Keratitis after Phacoemulsification Cataract Surgery.

Case Rep Ophthalmol Med 2017 6;2017:6413160. Epub 2017 Nov 6.

Harkness Eye Institute, Columbia University Medical Center, 635 West 165th Street, New York, NY 10032, USA.

The purpose of this manuscript is to report the case of an 81-year-old patient who presented with bilateral keratitis after phacoemulsification surgery. Cultures came back positive for . Despite aggressive topical and systemic antimicrobial treatment, the patient developed a corneal perforation in both eyes, treated with corneal glue in the right eye and corneoscleral patch in the left eye. Read More

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https://www.hindawi.com/journals/criopm/2017/6413160/
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http://dx.doi.org/10.1155/2017/6413160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694989PMC
November 2017
4 Reads

Infection at Umbilical Hernioplasty Site.

J Clin Diagn Res 2017 Sep 1;11(9):OD01-OD02. Epub 2017 Sep 1.

Associate Professor, Department of Microbiology, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.

Non Tuberculous Mycobacteria (NTM) are a group of rapidly growing mycobacteria and are generally considered to be of low virulence. Of late, there has been an increase in incidence of infections due to these organisms. Among them, are the common species which have been identified. Read More

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http://jcdr.net/article_fulltext.asp?issn=0973-709x&year
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http://dx.doi.org/10.7860/JCDR/2017/26618.10531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713780PMC
September 2017
6 Reads

Sporotrichoid pattern of Mycobacterium chelonae-abscessus infection.

Cutis 2017 09;100(3):E4-E5

Department of Dermatology, Baylor College of Medicine, Houston, Texas, USA.

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September 2017
7 Reads

Identification of the Infection Source of an Outbreak of Mycobacterium Chelonae Keratitis After Laser in Situ Keratomileusis.

Cornea 2018 Jan;37(1):116-122

Department of Ophthalmology and Visual Sciences, Paulista School of Medicine, Federal University of São Paulo, São Paulo, Brazil. Martins Bispo is now with at the Departments of Ophthalmology, Microbiology and Immunobiology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA.

Purpose: Nontuberculous mycobacteria keratitis is a rare but challenging complication of laser in situ keratomileusis (LASIK). This study was conducted to determine the source(s) of infection in a cluster of cases of keratitis after LASIK and to describe this outbreak and patients' outcomes.

Methods: In this retrospective, case series, single-center study, 86 patients were included who underwent LASIK or photorefractive keratectomy between December 2011 and February 2012. Read More

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http://Insights.ovid.com/crossref?an=00003226-201801000-0002
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http://dx.doi.org/10.1097/ICO.0000000000001423DOI Listing
January 2018
19 Reads

Differential Identification of Mycobacterial Species Using High-Resolution Melting Analysis.

Front Microbiol 2017 23;8:2045. Epub 2017 Oct 23.

Infectious and Tropical Diseases Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Infections caused by non-tuberculous mycobacteria (NTM) is increasing wordwide. Due to the difference in treatment of NTM infections and tuberculosis, rapid species identification of mycobacterial clinical isolates is necessary for the effective management of mycobacterial diseases treatment and their control strategy. In this study, a cost-effective technique, real-time PCR coupled with high-resolution melting (HRM) analysis, was developed for the differentiation of Mycobacterial species using a novel sequence. Read More

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http://dx.doi.org/10.3389/fmicb.2017.02045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660063PMC
October 2017
2 Reads

Comment on Mycobacterium Chelonae Infection of the Buttocks Secondary to Lipofilling: A Case Report and Review of the Literature.

Authors:
Masoud Keikha

Aesthetic Plast Surg 2018 04 3;42(2):610. Epub 2017 Nov 3.

Department of Microbiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

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http://dx.doi.org/10.1007/s00266-017-1005-xDOI Listing
April 2018
4 Reads

Blood antimicrobial activity varies against different Mycobacterium spp.

Tuberculosis (Edinb) 2017 12 24;107:80-87. Epub 2017 Aug 24.

Servicio de Microbiología Clínica, Complejo Asistencial Universitario de León (CAULE), Altos de Nava, s/n, 24008 León, Spain.

In vitro analysis of mycobacterial pathogenicity or host susceptibility has traditionally relied on the infection of macrophages, the target cell of mycobacteria, despite difficulties reproducing their antimycobacterial activity. We have employed alternative models, namely whole blood and leukocytes in plasma, from QuantiFERON negative individuals, and performed infections with the pathogenic M. tuberculosis, the less pathogenic M. Read More

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http://dx.doi.org/10.1016/j.tube.2017.08.008DOI Listing
December 2017
22 Reads

The new phylogeny of the genus Mycobacterium: The old and the news.

Infect Genet Evol 2017 12 11;56:19-25. Epub 2017 Oct 11.

Emerging Bacterial Pathogens Unit, IRCCS San Raffaele Scientific Institute, Milano, Italy. Electronic address:

Background: Phylogenetic studies of bacteria have been based so far either on a single gene (usually the 16S rRNA) or on concatenated housekeeping genes. For what concerns the genus Mycobacterium these approaches support the separation of rapidly and slowly growing species and the clustering of most species in well-defined phylogenetic groups. The advent of high-throughput shotgun sequencing leads us to revise conventional taxonomy of mycobacteria on the light of genomic data. Read More

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http://dx.doi.org/10.1016/j.meegid.2017.10.013DOI Listing
December 2017
19 Reads