2,962 results match your criteria Multilocular Cystic Nephroma


The temporomandibular joint: pneumatic temporal cells open into the articular and extradural spaces.

Folia Morphol (Warsz) 2018 Dec 11. Epub 2018 Dec 11.

The pneumatization of the articular tubercle (PAT) of the temporal squama is a rare condition that modifies the barrier between the temporomandibular joint (TMJ) space and the middle cranial fossa. During a routine examination of the cone beam computed tomography (CBCT) files of patients who were scanned for dental medical purposes, we identified a case with multiple rare anatomic variations. First, the petrous apex was bilaterally pneumatized. Read More

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December 2018

A case of huge lymphatic and venous malformations of the mediastinum.

Respir Med Case Rep 2019 22;26:53-55. Epub 2018 Nov 22.

Department of Respiratory Medicine, Iizuka Hospital, 3-83 Yoshiomachi, Iizuka, Fukuoka 820-0018, Japan.

We herein report a case of huge lymphatic and venous malformations of the mediastinum (LVM). A 19-year-old man presented for evaluation of a mediastinal mass. On chest computed tomography, the mass demonstrated contrast enhancement and showed dilated veins draining into the superior and inferior vena cava, with multiple scattered calcifications. Read More

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November 2018

A paracrine role for white thermogenic adipocytes in innervation: an evidence-based hypothesis.

Neural Regen Res 2019 Feb;14(2):217-221

Department of Human Sciences, The Ohio State University, Columbus, OH, USA.

White adipose tissue (WAT) stores energy and also plays an important endocrine role in producing adipokines for communication with the peripheral and central nervous system. WAT consists of the major lipogenic unilocular adipocytes and the minor populations of beige and brite multilocular adipocytes. These multilocular adipocytes express thermogenic genes and have phenotypic similarity with thermogenic brown adipose tissue. Read More

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February 2019

Electric stimulation of ears accelerates body weight loss mediated by high-fat to low-fat diet switch accompanied by increased white adipose tissue browning in C57BL/6 J mice.

BMC Complement Altern Med 2018 Dec 5;18(1):323. Epub 2018 Dec 5.

Institute of Nutrition, China Medical University, Taichung, 40402, Taiwan.

Background: Weight reduction frequently occurs in patients receiving vagus nerve stimulation (VNS) therapy. Therefore, we hypothesized that during dietary intervention for weight loss, auricular electric stimulation (AES), an alternative of VNS, accelerates weight loss by increasing white adipose tissue (WAT) browning and increases energy expenditure.

Methods: C57BL/6J male mice were fed a high-fat diet for 5 wk. Read More

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December 2018

A case of venous malformation of the mandible.

Oral Radiol 2018 May 23. Epub 2018 May 23.

Department of Oral and Maxillofacial Radiology and Diagnosis, School of Dental Medicine, Tsurumi University, 2-1-3 Tsurumi, Tsurumi Ward, Yokohama, Kanagawa, 230-8501, Japan.

Objective: Vascular malformations occur more rarely in bones than in soft tissue, with 0.5-1.0% of all intraosseous tumors occurring in the mandible. Read More

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May 2018
5 Reads

Prevalence and characteristics of pneumatizations of the articular eminence and roof of the glenoid fossa on cone-beam computed tomography.

Oral Radiol 2018 May 21. Epub 2018 May 21.

Department of Dentomaxillofacial Radiology, Health Sciences University, Av. Emrah, 06018, Kecioren, Ankara, Turkey.

Objective: The aim of this study was to determine the prevalence and characteristics of pneumatization of the articular tubercle (PAT) and pneumatization of the roof of the glenoid fossa (PRGF) in a large population using cone-beam computed tomography (CBCT).

Materials And Methods: This study was designed to evaluate the CBCT images of 1000 patients. The prevalences of the pneumatizations by age, sex, locularity, and laterality were determined. Read More

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May 2018
4 Reads

Thymic inflammatory pseudotumor with multilocular thymic cyst caused by immunoglobulin G4-related disease.

Thorac Cancer 2018 Nov 23. Epub 2018 Nov 23.

Department of Oncology, Immunology and Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.

A 44-year-old man was referred to our hospital after an anterior mediastinal tumor was noted on computed tomography during follow-up observation after left testicular seminoma resection. Chest computed tomography revealed an enhanced mass measuring 33 x 16 x 15 mm at the anterior mediastinum. Chest magnetic resonance imaging revealed high signal intensity on T2-weighted imaging, and F  fluorodeoxyglucose-positron emission tomography showed a maximum standardized uptake of 12. Read More

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November 2018
5 Reads

Eruption of a venous malformation through an iliac bone harvesting site after trauma.

Arch Plast Surg 2018 Nov 15;45(6):588-592. Epub 2018 Nov 15.

Department of Plastic and Reconstructive Surgery, St. Mary's Hospital, Kurume, Japan.

Harvesting grafts from the anterior iliac bone has been associated with various complications. A 50-year-old woman presented to our department with a chief complaint of right inguinal swelling and pain. Autologous bone grafts had been harvested on two previous occasions from the right anterior iliac crest for use in the reconstruction of multiple facial fractures. Read More

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November 2018
6 Reads

Fruit Morphology and Anatomy of the Spondioid Anacardiaceae.

Bot Rev 2018 3;84(4):315-393. Epub 2018 Aug 3.

5Florida Museum of Natural History, University of Florida, Gainesville, FL USA.

The Spondioideae subfamily of the Anacardiaceae is widely distributed today in tropical regions. Recent molecular phylogenetic investigations indicate that the Spondioideae are not monophyletic, but rather comprise at least two separate clades that are difficult to distinguish using vegetative and floral characters. Nevertheless, the syndrome of fruit characters traditionally used in identifying the subfamily is useful in discriminating genera of these clades and for identification of both modern and fossil anacardiaceous fruits. Read More

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August 2018
3 Reads

Allicin induces beige-like adipocytes via KLF15 signal cascade.

J Nutr Biochem 2018 Sep 23;64:13-24. Epub 2018 Sep 23.

School of Pharmacy, Sungkyunkwan University, Suwon, Gyunggi-do, 440-746, Republic of Korea. Electronic address:

Under specific conditions, white adipose tissue (WAT) depots are readily converted to a brown-like state, which is associated with weight loss. However, whether diet-derived factors directly induce browning of white adipocytes has yet to be established. Thus, we investigated the effects of allicin, one of the major components of garlic, on brown-like adipocyte formation in inguinal WAT (iWAT), and prevention of obesity and related complications in animal models. Read More

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September 2018
2 Reads

Laparoscopic approach to tailgut cyst (retrorectal cystic hamartoma).

J Minim Access Surg 2018 Nov 9. Epub 2018 Nov 9.

Department of Surgery, Hospital Quironsalud San José, Madrid, Spain.

Retrorectal cystic hamartomas, or tailgut cysts, are complex congenital cystic lesions which arise from embryologic tissues. Fewer than 200 cases have been reported worldwide, with women outnumbering men by 3:1. They are asymptomatic in 50% of the cases; the remainder present with back pain or mass effect as the most common symptoms. Read More

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November 2018
8 Reads

GLP-1RA promotes brown adipogenesis of C3H10T1/2 mesenchymal stem cells via the PI3K-AKT-mTOR signaling pathway.

Biochem Biophys Res Commun 2018 Dec 4;506(4):976-982. Epub 2018 Nov 4.

Division of Geriatrics, Drum Tower Clinic Medical College of Nanjing Medical University, Nanjing, China; Department of Chemistry, State Key Laboratory of Analytical Chemistry for Life Science, Nanjing University, Nanjing, China. Electronic address:

Objective: In this study, we investigated whether the GLP-1RA, liraglutide, affected differentiation of C3H10T1/2 mesenchymal stem cells (MSCs) to mature brown adipocytes and involvement of PI3K/AKT/mTOR signaling pathway in this process.

Methods: C3H10T1/2 MSCs were induced to differentiate into brown adipocytes and treated with liraglutide (10 nM and 100 nM) for 0, 2, 4, 6 and 8 days with or without PI3K inhibitor LY294002. Oil red O staining was used for lipid droplet staining and cell proliferation was determined by cell counts. Read More

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December 2018
6 Reads

Morphological and Taxonomic Interpretation of Orestovia and Schuguria, Enigmatic Devonian Plants from Russia.

Authors:
A V Gomankov

Dokl Biol Sci 2018 Sep 6;482(1):182-184. Epub 2018 Nov 6.

Komarov Botanical Institute, Russian Academy of Sciences, St. Petersburg, Russia.

A detailed study of the external and internal surfaces of the cuticle of Orestovia and Schuguria using scanning electron microscopy and confocal laser microscopy has shown that the structures formerly interpreted as stomata or reproductive organs are most likely to be gland cells producing mucilage. Each structure represents a single large cell with a complex aperture on the external wall. In addition, a reproductive organ similar to multilocular sporangia known in brown algae of the order Ectocarpales has been found in attachment to a compression fossil of Orestovia. Read More

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September 2018
1 Read

[A Case of Liver Metastasis of Colorectal Cancer Undifferentiated from Biliary Cystadenocarcinoma].

Gan To Kagaku Ryoho 2018 Oct;45(10):1516-1518

Dept. of Surgery, Yokohama City University.

A 74-year-old woman was found to have a hepatic mass based on CT findings. She was diagnosed as having cecum cancer, and it was difficult to distinguish whether the hepatic mass was liver metastasis or biliary cystadenocarcinoma. We proceeded with the surgery for cecum cancer, and laparoscopic ileocecal resection with D3 lymph node dissection was performed. Read More

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October 2018

[Arthroscopic cyst removal and wire-guided suture for the treatment of lateral meniscal cyst of knee joint].

Zhongguo Gu Shang 2018 Oct;31(10):944-948

Department of Knee Injury, Luoyang Orthopaedic Hospital of Henan Province, Luoyang 471002, Henan, China.

Objective: To explore clinical effect of arthroscopic cyst removal and wire-guided suture for the treatment of lateral meniscal cyst of knee joint.

Methods: From July 2014 to December 2017, 33 patients with lateral meniscal cyst of knee joint were treated by arthroscopic cysts removal and wire-guided suture, including 13 males and 20 females, aged from 20 to 55 years old with an average age of(36.23 ±2. Read More

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October 2018
2 Reads

Standardized Photographic Documentation of Hidradenitis Suppurativa/Acne Inversa.

Dermatology 2019 26;235(1):51-54. Epub 2018 Oct 26.

Experimental Medicine and Diagnostics, Global Exploratory Development, UCB BioPharma SPRL, Braine L'Alleud, Belgium.

Background: Despite existing guidelines and methods for standardized clinical photography in dermatology and plastic surgery, human skin exhibits exquisite site-specific morphologies and functions, and each body region can exhibit an individual pathologic phenotype. The aim of this work was to develop a standardized, representative and reproducible documentation of the multilocular hidradenitis suppurativa/acne inversa (HS) lesions, a disease mostly occurring in skin folds.

Method: Optimal body positions for medical photography of candidate areas for HS involvement were evaluated. Read More

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October 2018
1 Read

A case report of infantile cystic nephroblastoma.

Diagn Pathol 2018 Oct 27;13(1):84. Epub 2018 Oct 27.

Department of Pathology and Laboratory Medicine, Kanazawa Medical University, 1-1 Daigaku, Uchinada, Ishikawa, 920-0293, Japan.

Background: Nephroblastoma (NB) is a malignant embryonal neoplasm derived from nephrogenic blastemal cells. NB usually forms a solid mass, but in extremely rare cases, it may show cystic changes.

Case Presentation: A six-month-old girl with persistent high fevers was found to have pyuria and bacteriuria. Read More

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October 2018
4 Reads

Giant internal iliac artery aneurysm successfully treated with endovascular stent-graft placement.

Interv Med Appl Sci 2018 Mar;10(1):54-58

Department of Radiology, Arkalochori Medical Center, Crete, Greece.

An 88-year-old male patient of high surgical risk was presented with left sciatic pain symptoms and a palpable pulsatile left lower abdominal mass. He was operated 8 years ago for a large infrarenal aortic aneurysm. Computed tomography angiography (CTA) revealed a giant 161 mm left internal iliac aneurysm with multilocular appearance and left sacral bone erosion causing the symptoms. Read More

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March 2018
4 Reads

Successful partial nephrectomy of a T1b multilocular clear cell renal cell carcinoma arising in a renal graft.

Urol Case Rep 2019 Jan 5;22:19-20. Epub 2018 Oct 5.

Clinical Institute of Urology and Renal Transplantation, Transplantation Department, 4-6 Clinicilor Street, 400006, Cluj-Napoca, Romania.

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January 2019
7 Reads

Zic1 mRNA is transiently upregulated in subcutaneous fat of acutely cold-exposed mice.

J Cell Physiol 2019 Mar 20;234(3):2031-2036. Epub 2018 Oct 20.

Department of Experimental and Clinical Medicine, Center of Obesity, University of Ancona (Politecnica delle Marche), Ancona, Marche, Italy.

In the mammalian adipose organ cold exposure not only activates typical brown adipose tissue, but also induces browning, that is the formation of thermogenic multilocular adipocytes in white, or predominantly white, adipose depots such as subcutaneous fat. Unlike typical brown adipocytes, newly formed thermogenic adipocytes have been reported not to express the gene zinc finger of the cerebellum 1 (Zic1). Here, a time course approach enabled us to document a significant increase in Zic1 messenger RNA in inguinal subcutaneous fat from acutely (24 hr) cold-exposed mice, which was paralleled by an increase in multilocular and paucilocular uncoupling protein 1-positive adipocytes and in parenchymal noradrenergic innervation. Read More

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[Complications in orthopedic rheumatology-characteristics of operative procedures].

Authors:
L Bause

Orthopade 2018 Nov;47(11):947-955

CA Klinik für Rheumaorthopädie, St. Josef-Stift Sendenhorst, Westtor 7, 48324, Sendenhorst, Deutschland.

The introduction of biologics has led to a great improvement in the treatment options for inflammatory rheumatic diseases. Nevertheless, surgical interventions are still necessary in many patients but a change in surgical indications could be observed. The previously predominant synovectomy of inflamed rheumatic joints is now reduced to a few so-called rebellious joints with persistent inflammation. Read More

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November 2018
2 Reads

Mucinous cystadenoma of pancreas with honeycombing appearance: Radiological-Pathological correlation.

Indian J Radiol Imaging 2018 Jul-Sep;28(3):327-329

Department of Radiodiagnosis, Sree Balaji Medical College and Hospital, Chromepet, Chennai, Tamil Nadu, India.

Most mucinous cystadenomas of pancreas are solitary and multilocular with a few large compartments. Serous cystadenomas usually have a polycystic or microcystic (honeycomb) pattern consisting of collection of cysts (usually >6) that range from few millimetres up to 2 cm in size. Here we present a case of mucinous cystadenoma of pancreas showing an unusual appearance of honeycombing (which has not been described so far) using imaging studies such as endoscopic ultrasound and computed tomography with histopathological confirmation of the diagnosis. Read More

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October 2018
1 Read

Jaw tumor in recurrent primary hyperparathyroidism: A case report.

Int J Surg Case Rep 2018 4;52:54-58. Epub 2018 Oct 4.

Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran; Obesity and Eating Habits Research Center, Endocrinology and Metabolism Molecular -Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

Background: Brown tumor may present as uni/multilocular osteolytic lesions with bone expansion, bone pain or pathologic fracture in primary, secondary and tertiary hyperparathyroidism. However, recently, such presentation is rare due to early detection using blood screening techniques before symptomatic bone lesions appear.

Case Report: A 65-year-old woman was admitted to our hospital with generalized bone pain and a progressive painless mass in her jaw appeared since 6 months ago. Read More

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October 2018
1 Read

Contemporary update on imaging of cystic renal masses with histopathological correlation and emphasis on patient management.

Clin Radiol 2018 Oct 9. Epub 2018 Oct 9.

Department of Medical Imaging, The Ottawa Hospital, University of Ottawa, 501 Smyth Road, Ottawa, ON K1H 8L6, Canada. Electronic address:

This article presents an updated review of cystic renal mass imaging. Most cystic renal masses encountered incidentally are benign and can be diagnosed confidently on imaging and require no follow-up. Hyperattenuating masses discovered at unenhanced or single-phase enhanced computed tomography (CT) measuring between 20-70 HU are indeterminate and can be further investigated first by using ultrasound and, then with multi-phase CT or magnetic resonance imaging (MRI); as the majority represent haemorrhagic/proteinaceous cysts (HPCs). Read More

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October 2018
5 Reads

Three new mealybug species (Hemiptera: Coccomorpha: Pseudococcidae) from Iran.

Zootaxa 2018 May 16;4420(2):180-188. Epub 2018 May 16.

Insect Taxonomy Research Department, Iranian Research Institute of Plant Protection (IRIPP), Agricultural Research Education and Extension Organization (AREEO), Tehran, P.O. Box 19395-1454, Iran..

Three new mealybug species, Dysmicoccus caspianensis sp. n., Dysmicoccus zagrosicus sp. Read More

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Early adipose deposits in sheep: comparative analysis of the perirenal fat transcriptome of Assaf and Churra suckling lambs.

Anim Genet 2018 Dec 12;49(6):605-617. Epub 2018 Oct 12.

Departamento de Producción Animal, Facultad de Veterinaria, Universidad de León, Campus de Vegazana s/n, León, 24071, Spain.

Adipose deposits influence the quality of ruminant carcasses, and in suckling lambs, internal types of adipose deposits represent a notable proportion of total fat. The aim of this study was to perform a comparative analysis of the perirenal fat transcriptomes of suckling lambs from two breeds with different growth and carcass characteristics. The perirenal fat tissue from 14 suckling lambs (Assaf, n = 8; Churra, n = 6) was used for the RNA-seq analysis. Read More

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December 2018

Large Multilocular Cystic Lesions in the Uterine Cervix: Differential Diagnosis and Significance.

J Med Ultrasound 2018 Jul-Sep;26(3):153-156. Epub 2018 May 7.

Department of Obstetrics and Gynecology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.

Introduction: Cervical nabothian cysts are common in women of reproductive age. Although cysts are generally small and asymptomatic, large ones are extremely rare and may be misdiagnosed as malignancy.

Case Study: We report a case of large multiple complex nabothian cyst, which was suspected as malignant one on imaging and examination. Read More

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May 2018
8 Reads

Fat Grafting Can Induce Browning of White Adipose Tissue.

Plast Reconstr Surg Glob Open 2018 Jun 19;6(6):e1804. Epub 2018 Jun 19.

Department of Plastic and General Surgery, Turku University Hospital, Turku, Finland.

Background: Fat grafting is commonly used when treating soft-tissue defects. However, much of the basic biology behind fat transfer is still uncovered. Adipocytes can be divided into energy storing white and energy burning brown adipose cells. Read More

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June 2018
1 Read

Activation of estrogen receptor alpha induces beiging of adipocytes.

Mol Metab 2018 Dec 15;18:51-59. Epub 2018 Sep 15.

Department of Biomedical Sciences, Diabetes & Obesity Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA. Electronic address:

Objectives: Brown adipose tissue (BAT) and BAT-like adipose tissues, referred to as 'beige' adipose tissues uncouple respiration from ATP synthesis via uncoupling protein one (UCP-1). There is a sexual dimorphism with respect to beige and BAT tissues; pre-menopausal women have more BAT and are more sensitive to BAT activation than men or postmenopausal women. We hypothesized selective activation of adipose tissue estrogen receptor alpha (ERα) induces beiging of WAT through induction of lipolysis mediated by adipose tissue triglyceride lipase (ATGL). Read More

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December 2018
1 Read

The glomus tumor resorbed bone and teeth in the mandible: a case report.

Head Face Med 2018 Sep 25;14(1):18. Epub 2018 Sep 25.

Department of Maxillofacial Surgery, Division of Maxillofacial and Neck Reconstruction, Graduate School of Tokyo Medical and Dental University, Tokyo, Japan.

Background: A glomus tumor is a rare neoplasm usually found in the dermis or subcutaneous tissue of the extremities. It is rare for the glomus tumor to occur on the head and face. Only 26 glomus tumors of the oral region and affected bone have been reported in the English-language literature (Table 1). Read More

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September 2018
9 Reads

Diagnostic challenges of an unusually large schwannoma of the mandible: Report of a case.

Saudi Dent J 2018 Oct 30;30(4):373-378. Epub 2018 Jun 30.

Department of Oral and Maxillofacial Surgery, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.

Schwannomas are slow-growing, benign neoplasms arising from the Schwann cells and are commonly reported as peripheral tumors in the head and neck region. Central intramandibular schwannomas are extremely rare lesions. We report a case of intramandibular schwannoma in a 70 year old male patient. Read More

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October 2018
5 Reads

Combination of Capsaicin and Hesperidin Reduces the Effectiveness of Each Compound To Decrease the Adipocyte Size and To Induce Browning Features in Adipose Tissue of Western Diet Fed Rats.

J Agric Food Chem 2018 Sep 5;66(37):9679-9689. Epub 2018 Sep 5.

Laboratory of Molecular Biology, Nutrition and Biotechnology (Nutrigenomics and Obesity Group) , University of the Balearic Islands , 07122 Palma , Spain.

We explored the potential of hesperidin and capsaicin, separately and in combination, to induce white adipose tissue (WAT) browning and to help body weight management in Western diet-fed rats. Adult male Wistar rats were fed for 8 weeks with Western diet and treated daily with hesperidin (100 mg/kg/day), capsaicin (4 mg/kg/day), hesperidin (100 mg/kg/day) + capsaicin (4 mg/kg/day), or the vehicle. Hesperidin and capsaicin separately, but not (or to a lesser extent) the combination, resulted in a decreased size of adipocytes and induced emergence of multilocular brown-like adipocytes positive for UCP1 and CIDEA in retroperitoneal WAT. Read More

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September 2018

Struma ovarii - ultrasound features of a rare tumor mimicking ovarian cancer.

Med Ultrason 2018 Aug;20(3):355-361

Department of Gynecology and Obstetrics Charles University in Prague-First Faculty of Medicine and Hospital Na Bulovce, Czech Republic.

Aims: To describe the ultrasound features of benign struma ovarii that often mimic ovarian cancer in the background of complex clinical and histopathological pictures.

Material And Methods: We retrospectively identified patients with histologically confirmed benign struma ovarii, treated in our institution between 2003-2016 with complete imaging, clinical, nd histopathological data available. Ultrasound findings were drawn from images, and reports using terms and definitions of the International Ovarian Tumor Analysis group and pattern recognition description was applied. Read More

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August 2018
7 Reads

Aneurysmal Bone Cyst of 3rd Metacarpal, Management and Follow-up: A Case Report.

J Orthop Case Rep 2018 Mar-Apr;8(2):9-12

Consultant Orthopaedic Hand Surgeon, Lilavati Hospital and Research Centre Mumbai, Maharashtra, India.

Introduction: Aneurysmal bone cysts of the hand are rare, and only few cases are reported in scientific literature. We report a case of aneurysmal bone cyst of 3rd metacarpal treated at our tertiary care hospital, Mumbai.

Case Report: A 13-year-old young female presented with pain and progressive increase in swelling over the dorsum of the right hand for 7-months. Read More

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September 2018
5 Reads

Multiple myeloma presenting as an unhealed extraction socket: Report of a case with brief review of literature.

J Oral Maxillofac Pathol 2018 May-Aug;22(2):284

Department of Oral Medicine and Radiology, Subharti Dental College, Meerut, Uttar Pradesh, India.

Multiple myeloma (MM) is a relatively rare malignant hematological disease, which is characterized by a monoclonal malignant proliferation of plasma cells that causes osteolytic lesions. Maxillofacial presentations in patients with MM are not uncommon, but because the symptoms are varied, it is very difficult to diagnose MM in this region especially in patients with initial oral involvement. Furthermore, maxillofacial manifestations as an initial sign or symptom are scarce. Read More

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August 2018
6 Reads

MFN2-associated lipomatosis: Clinical spectrum and impact on adipose tissue.

J Clin Lipidol 2018 Nov - Dec;12(6):1420-1435. Epub 2018 Jul 25.

Sorbonne Université, Inserm UMR_S 938, Centre de Recherche Saint-Antoine, Institut Hospitalo-Universitaire de Cardio-métabolisme et Nutrition (ICAN), Paris, France; Assistance Publique-Hôpitaux de Paris, Hôpital Saint-Antoine, Laboratoire Commun de Biologie et Génétique Moléculaires, Paris, France.

Background: Multiple symmetric lipomatosis (MSL) is characterized by upper-body lipomatous masses frequently associated with metabolic and neurological signs. MFN2 pathogenic variants were recently implicated in a very rare autosomal recessive form of MSL. MFN2 encodes mitofusin-2, a mitochondrial fusion protein previously involved in Charcot-Marie-Tooth neuropathy. Read More

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July 2018
2 Reads

Ancillary studies in fine needle aspiration of the kidney.

Cancer Cytopathol 2018 Aug;126 Suppl 8:711-723

Baptist Hospital of Miami and Miami Cancer Institute, Miami, Florida.

An increasing number of renal cell carcinomas (RCCs) require ancillary studies for diagnosis. The majority of renal fine needle aspirates do not require ancillary studies. Among the most common useful stains are cytokeratin 7 (separating clear cell RCC [negative] from papillary RCC, clear cell papillary RCC, and multilocular cystic RCC [positive] as well as separating chromophobe RCC [diffusely positive] from oncocytoma [focally positive/negative]) and CD117 (separating chromophobe RCC and oncocytoma [positive] from granular variants of clear cell RCC [negative]). Read More

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August 2018
9 Reads

Frozen Section Diagnostic Pitfalls of Sertoli-Leydig Cell Tumor with Heterologous Elements.

Case Rep Pathol 2018 25;2018:5151082. Epub 2018 Jul 25.

Brooke Army Medical Center, San Antonio, TX, USA.

A woman in her sixth decade presented with several months of abdominal cramping, decreased appetite, bloating, and increased constipation. Radiologic imaging revealed a 28 cm, multilocular, heterogeneous cystic neoplasm involving the right adnexa. An intraoperative frozen section showed mucinous glandular epithelium, with and without foci of goblet cells, embedded in apparent ovarian stroma. Read More

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July 2018
6 Reads

Central odontogenic fibroma: An updated systematic review of cases reported in the literature with emphasis on recurrence influencing factors.

J Craniomaxillofac Surg 2018 Oct 7;46(10):1753-1757. Epub 2018 Aug 7.

Oral Surgery and Pathology Department, João de Barros Barreto University Hospital, Federal University of Pará, Belém, Pará, Brazil. Electronic address:

Purpose: To integrate the available data published on central odontogenic fibroma (COF) into a comprehensive analysis of its clinical/radiologic/histological features.

Methods: An electronic search was undertaken in September 2017. Eligibility criteria included publications reporting cases of COF having enough clinical, radiological and histological information to confirm the diagnosis. Read More

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October 2018
7 Reads

[Transurethral resection of prostate treatment for recurrence of a multilocular prostatic cystadenoma: a case report].

Beijing Da Xue Xue Bao Yi Xue Ban 2018 Aug;50(4):740-742

Department of Urology, Peking University People's Hospital, Beijing 100044, China.

Multilocular prostatic cystadenoma (MPC) is a rare benign tumor that originates from the prostate itself. MPC is usually characterized by large multilocular cysts located between the rectum and bladder. The clinical presentation includes obstructive voiding symptoms, such as poor stream, intermittency, sensation of incomplete emptying, acute urinary retention and sometimes constipation symptoms due to mechanical compression of the lower intestine. Read More

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August 2018
1 Read

An Immature Ten-year Long-standing Case of Ossifying Fibroma.

Cureus 2018 Jun 11;10(6):e2782. Epub 2018 Jun 11.

Department of Oral Medicine and Diagnostic Sciences, CWRU School of Dental Medicine, Cleveland, USA.

Ossifying fibroma is a rare benign bone neoplasm common in middle age, with definite female predominance. Here, we describe a case of an ossifying fibroma in a 36-year-old female, with a right facial deformity. The lesion had been present for almost 10 years. Read More

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June 2018
9 Reads

Rab27a Regulates Human Perivascular Adipose Progenitor Cell Differentiation.

Cardiovasc Drugs Ther 2018 Oct;32(5):519-530

Center for Molecular Medicine, Maine Medical Center Research Institute, 81 Research Drive, Scarborough, ME, 04072, USA.

Purpose: Perivascular adipose tissue (PVAT) surrounds blood vessels and regulates vascular tone through paracrine secretion of cytokines. During conditions promoting cardiometabolic dysfunction, such as obesity, cytokine secretion is altered towards a proinflammatory and proatherogenic profile. Despite the clinical implications for cardiovascular disease, studies addressing the biology of human PVAT remain limited. Read More

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October 2018

Comparison of endometriotic cysts and ovarian cancer in association with endometriotic cysts.

Cancer Treat Res Commun 2018 13;14:26-29. Epub 2017 Nov 13.

Department of Obstetrics and Gynecology, Kochi Health Sciences Center, 2125 Ike, Kochi 781-8555, Japan.

Objective: The aim of this study was to clarify the clinical, laboratory, and imaging findings of ovarian cancer in association with endometriotic cysts by detailed comparison of the findings of benign and malignant tumors.

Methods And Materials: This was a retrospective study of 138 women who had an operation for ovarian tumors at the Department of Obstetrics and Gynecology of Kochi Health Sciences Center between September 1, 2011, and July 30, 2015. The ovarian tumors were divided into two groups: the benign group (endometriotic cysts) and the malignant group (ovarian cancer in association with endometriotic cysts). Read More

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November 2017
1 Read

Neurilemmoma Mimicking a Multilocular Cystic Lesion of the Liver.

Intern Med 2018 Dec 10;57(23):3377-3380. Epub 2018 Aug 10.

Department of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan.

Neurilemmomas are benign tumors arising from the sheaths of peripheral nerves. They appear rarely in the abdominal cavity. We herein report an 80-year-old man with a multilocular cystic neurilemmoma mimicking a liver lesion. Read More

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December 2018
2 Reads

Radiographic Diagnosis of a Central Giant Cell Granuloma Using Advanced Imaging: Cone Beam Computed Tomography.

Cureus 2018 Jun 5;10(6):e2735. Epub 2018 Jun 5.

Department of Oral Medicine and Diagnostic Sciences, CWRU School of Dental Medicine, Cleveland, USA.

Central giant cell granuloma (CGCG) is a benign non-neoplastic, proliferative intraosseous lesion of the jaw with an unknown etiology often diagnosed during the first two decades of life. The true nature of this lesion is controversial and remains elusive. Here, we report a case of central giant cell granuloma, diagnosed using cone-beam computed tomography (CBCT). Read More

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June 2018
5 Reads

Evaluation of pineal cysts with magnetic resonance imaging.

World J Radiol 2018 Jul;10(7):65-77

Department of Radiology, Tokat State Hospital, Tokat 60100, Turkey.

Aim: To evaluate radiological imaging findings of patients who had been found to have pineal cyst (PC) in brain magnetic resonance imaging (MRI).

Methods: A total of 9546 patients who had brain MRI examination in March 2010-January 2018 period were studied. Fifty-six patients (44 female and 12 male) found to have PC were evaluated. Read More

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July 2018
1 Read

Multilocular thymic cyst in a patient with Sjögren syndrome.

Rheumatology (Oxford) 2018 Jul 26. Epub 2018 Jul 26.

Department of Radiology, Ramón y Cajal University Hospital, Madrid, Spain.

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July 2018
3 Reads
4.470 Impact Factor

Newly Categorized Seromucinous Tumor of the Ovary: Magnetic Resonance Imaging Findings.

J Comput Assist Tomogr 2018 Jul 27. Epub 2018 Jul 27.

From the Departments of Radiology and.

Objective: The aim of this study was to describe magnetic resonance imaging findings of newly categorized ovarian seromucinous tumors.

Methods: We retrospectively reviewed the images of 29 patients with seromucinous tumor for the following factors: size, configuration, signal intensity (SI), and accompanying ovarian endometriosis.

Results: Thirty-two tumors (17 benign, 7 borderline, 8 carcinoma) were found on computed tomography or magnetic resonance imaging. Read More

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July 2018
2 Reads
1.600 Impact Factor