- Bharat Kumar,
- S Rahnama-Moghadam,
- Karolyn A Wanat,
- Jacob W Ijdo,
- Victoria P Werth,
- Namrata Singh
J Clin Rheumatol 2017 Oct 20. Epub 2017 Oct 20.
From the *Division of Immunology, University of Iowa Hospitals and Clinics, Iowa City, IA; †Department of Dermatology, Indiana University, Indianapolis, IN; ‡Department of Dermatology and Pathology, University of Iowa Hospitals and Clinics, Iowa City, IA; §Griffith University School of Medicine and Gold Coast University Hospital, Southport, Queensland, Australia; ∥Medical Research, Corporal Michael J. Crescenz Veterans Affairs Medical Center (Philadelphia); and ¶Department of Dermatology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.
Objective: Multicentric reticulohistiocytosis is a rare systemic disease characterized by the presence of non-Langerhans cell histiocytic infiltrate in several organ systems. Because its clinical presentation so closely resembles autoimmune conditions such as rheumatoid arthritis, it is often overlooked as a diagnosis and, even when recognized, presents a challenge for treatment because of a lack of consensus regarding guidelines for management. We here review 6 cases of multicentric reticulohistiocytosis (MRH) from 2 institutions to identify clinical features, treatment, and outcomes of MRH. Read More