417 results match your criteria Multicentric Reticulohistiocytosis


Multicentric reticulohistiocytosis with arthralgia and red-orange papulonodules.

Cutis 2019 Jan;103(1):E20-E22

Department of Dermatology, Yale School of Medicine, New Haven, Connecticut, USA.

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January 2019

Cutaneous paraneoplastic syndromes.

Semin Diagn Pathol 2019 Jan 31. Epub 2019 Jan 31.

PRW Laboratories, Charlottesville, VA, United State.

A variety of cutaneous abnormalities can be seen in patients with malignant diseases, some of which are infectious, with others representing direct involvement of the skin by the underlying disorder. Yet another group of lesions can be regarded as associated markers of the malignant process, and, as such, are termed "paraneoplastic." This review considers the latter collection of conditions, grouping them by the generic type of malignancy that is usually linked to the paraneoplasia. Read More

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http://dx.doi.org/10.1053/j.semdp.2019.01.001DOI Listing
January 2019
1 Read

MULTISYSTEM NON-ARTHROPATHIC RETICULOHISTIOCYTOSIS Problems and pitfalls in the differential diagnosis of multisystem non-Langerhans cell histiocytoses.

J Eur Acad Dermatol Venereol 2019 Feb 1. Epub 2019 Feb 1.

Department of Pathophysiology and Transplantation, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.

Histiocytoses are rare proliferative disorders of the mononuclear-phagocyte system. Within non-Langerhans-cell histiocytoses (NLCH), multisystem (MS) cases potentially constitute a subset at high risk of complications and progression. The current 2016 revised classification subdivides histiocytoses in 5 groups, based on highly heterogeneous criteria. Read More

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http://dx.doi.org/10.1111/jdv.15461DOI Listing
February 2019
2 Reads

Erdheim-Chester disease bone lesions after cobimetinib initiation.

Arthritis Rheumatol 2019 Jan 28. Epub 2019 Jan 28.

University of Washington, 1959 NE Pacific St, BB561, Seattle, WA, 98195.

A 47 year-old man presented with cutaneous papules and hoarseness. Laryngoscopy showed supraglottic masses; histopathology revealed fibrohistiocytic proliferation with lipid-laden macrophages and Touton giant cells. Immunohistochemistry was positive for CD68 and negative for S100. Read More

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http://dx.doi.org/10.1002/art.40845DOI Listing
January 2019
1 Read

[Multicentric reticulohistiocytosis].

Hautarzt 2018 Oct;69(Suppl 1):56-58

Klinik und Poliklinik für Dermatologie und Allergologie, Ludwig-Maximilians-Universität München, Frauenlobstr. 9-11, 80337, München, Deutschland.

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http://dx.doi.org/10.1007/s00105-018-4187-5DOI Listing
October 2018
3 Reads

Multicentric reticulohistiocytosis: a case report.

BMC Res Notes 2018 Sep 4;11(1):647. Epub 2018 Sep 4.

Rheumatology Department, VUMC Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.

Background: Multicentric reticulohistiocytosis is a rare form of non-langerhans cell histiocytosis presenting with skin changes and erosive arthritis. Infiltration of histiocytes and multinucleated giant cells are typical histological findings and confirm the diagnosis.

Case Presentation: This case report describes a newly diagnosed case of multicentric reticulohistiocytosis in a healthy 26-year-old female originally from the Philippines. Read More

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http://dx.doi.org/10.1186/s13104-018-3753-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123928PMC
September 2018
2 Reads

The utility of FDG-PET/CT imaging in the evaluation of multicentric reticulohistiocytosis: A case report.

Medicine (Baltimore) 2018 Aug;97(33):e11449

Department of Rheumatology.

Introduction: Multicentric reticulohistiocytosis (MRH) is a rare histiocytic disorder that involves the skin, joints, and visceral organs.

Case Presentation: We report a 67-year-old woman with MRH who presented with a 2-years history of polyarthralgia and skin nodules. Her symptoms were an inflammatory polyarthropathy with punched-out lesions of the distal interphalangeal (DIP) joints of both hands. Read More

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http://dx.doi.org/10.1097/MD.0000000000011449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112898PMC
August 2018
15 Reads

Rare diseases of bone: Erdheim-Chester and Rosai-Dorfman non-Langerhans cell histiocytoses.

EFORT Open Rev 2018 Jun 23;3(6):381-390. Epub 2018 Jun 23.

Second Department of Internal Medicine, Hematology Unit, National and Kapodistrian University of Athens, School of Medicine, Greece.

Non-Langerhans cell histiocytosis (N-LCH) summarizes a group of rare diseases with different clinical presentations, pathogenesis and morphology. These include primary cutaneous N-LCH, cutaneous N-LCH with systemic involvement, and primary extracutaneous systemic forms with occasional cutaneous involvement.The juvenile (JXG) and non-juvenile xanthogranuloma (N-JXG) family of histiocytoses are N-LCH: the JXG family consisting of the JXG (cutaneous), xanthoma disseminatum (cutaneous and systemic) and Erdheim-Chester disease (ECD; systemic); and the N-JXG family consisting of the solitary reticulohistiocytoma (cutaneous), multicentric reticulohistiocytosis (cutaneous and systemic) and Rosai-Dorfman disease (RDD; systemic). Read More

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http://dx.doi.org/10.1302/2058-5241.3.170047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026883PMC
June 2018
3 Reads

Multicentric reticulohistiocytosis and metastatic colon carcinoma: an uncommon neoplasm recurrence manifestation.

G Ital Dermatol Venereol 2018 Jun;153(3):447-449

Unit of Dermatology, Department of Surgical, Microsurgical and Medical Sciences, University of Sassari, Sassari, Italy.

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http://dx.doi.org/10.23736/S0392-0488.17.05542-0DOI Listing
June 2018
6 Reads

A case of photodistributed multicentric reticulohistiocytosis: correlation with multiphoton microscopy imaging.

J Dtsch Dermatol Ges 2018 Jun 26;16(6):781-783. Epub 2018 Apr 26.

Department of Dermatology, University of California Irvine, Irvine, California, USA.

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http://dx.doi.org/10.1111/ddg.13515DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140325PMC
June 2018
8 Reads

Next-generation sequencing of idiopathic multicentric and unicentric Castleman disease and follicular dendritic cell sarcomas.

Blood Adv 2018 03;2(5):481-491

Department of Pathology, Stanford University, Stanford, CA.

Castleman disease (CD) is a rare lymphoproliferative disorder subclassified as unicentric CD (UCD) or multicentric CD (MCD) based on clinical features and the distribution of enlarged lymph nodes with characteristic histopathology. MCD can be further subtyped based on human herpes virus 8 (HHV8) infection into HHV8-associated MCD, HHV8/idiopathic MCD (iMCD), and polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin change (POEMS)-associated MCD. In a subset of cases of UCD, an associated follicular dendritic cell sarcoma (FDCS) may be seen. Read More

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http://dx.doi.org/10.1182/bloodadvances.2017009654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851414PMC
March 2018
3 Reads

[Multicentric reticulohistiocytosis is a rare form of paraneoplasia].

Ugeskr Laeger 2018 01;180(1)

A 59-year-old woman developed a rash and severe arthralgia, which primarily affected her fingers. She displayed digital arthritis and nodules on the hands, chest, face, and oral cavity. Blood samples were normal. Read More

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January 2018
13 Reads

Rare case of multicentric reticulohistiocytosis presenting as epidermotropic papular xanthoma and double primary cancers.

J Dermatol 2018 Jun 26;45(6):e138-e139. Epub 2017 Dec 26.

Department of Gastroenterology, Buddhist Tzu-Chi General Hospital and Tzu-Chi University, Hualien, Taiwan.

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http://dx.doi.org/10.1111/1346-8138.14182DOI Listing
June 2018
13 Reads

Xanthomatous Multicentric Reticulohistiocytosis: An Underrecognized Variant.

J Clin Rheumatol 2018 Aug;24(5):285-287

Division of Rheumatology Mayo Clinic Jacksonville, FL. Division of Rheumatology Mayo Clinic Jacksonville, FL Department of Dermatology Mayo Clinic Jacksonville, FL.

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http://dx.doi.org/10.1097/RHU.0000000000000652DOI Listing
August 2018
12 Reads

Castleman Disease and Rosai-Dorfman Disease.

Semin Diagn Pathol 2018 Jan 2;35(1):44-53. Epub 2017 Dec 2.

Pathology Service, Hospital Universitario Marques de Valdecilla, Santander, Spain.

This chapter describes the main features of two different diseases, Castleman Disease (CD) and Rosai-Dorfman Disease (RDD). Castleman disease (CD) is a clinical and histopathologically heterogeneous lymphoproliferative disorder that encompasses at least three distinct entities with some common overlapping morphological features: Hyaline Vascular CD (HVCD), Unicentric Plasma Cell CD and Multicentric CD. The most important feature of HVCD is the presence of abnormal germinal centers with hyaline-vascular transformation, sometimes showing multiple germinal centers within a single reactive lymphoid follicle, this outlining HVCD as a disorder of follicular dendritic cells. Read More

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http://dx.doi.org/10.1053/j.semdp.2017.11.014DOI Listing
January 2018
12 Reads

Multicentric Reticulohistiocytosis: A Multicenter Case Series and Review of Literature.

J Clin Rheumatol 2018 Jan;24(1):45-49

Division of Immunology University of Iowa Hospitals and Clinics Iowa City, IA Department of Dermatology Indiana University Indianapolis, IN Department of Dermatology and Pathology University of Iowa Hospitals and Clinics Iowa City, IA Griffith University School of Medicine and Gold Coast University Hospital Southport Queensland, Australia Medical Research Corporal Michael J. Crescenz Veterans Affairs Medical Center (Philadelphia) and Department of Dermatology Perelman School of Medicine at the University of Pennsylvania Philadelphia, PA.

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http://Insights.ovid.com/crossref?an=00124743-900000000-9944
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http://dx.doi.org/10.1097/RHU.0000000000000594DOI Listing
January 2018
41 Reads

Multicentric reticulohistiocytosis misdiagnosed as tenosynovial giant cell tumour.

Rheumatology (Oxford) 2017 Aug 11. Epub 2017 Aug 11.

Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.

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http://dx.doi.org/10.1093/rheumatology/kex312DOI Listing
August 2017
9 Reads

Multicentric Reticulohistiocytosis with Dermatomyositis-like Eruptions.

Intern Med 2017 1;56(15):2063-2066. Epub 2017 Aug 1.

Division of Rheumatology and Clinical Immunology, Department of Medicine, Jichi Medical University, Japan.

A 68-year-old man presented with polyarthritis, proximal muscle weakness, and erythema of the face, arms, neck, and anterior chest that resembled the V-neck sign. Initially, dermatomyositis (DM) was considered because of the erythema, polyarthritis, and muscle weakness. He also had mediastinal and hilar lymphadenopathy on contrast-enhanced computed tomography. Read More

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http://dx.doi.org/10.2169/internalmedicine.56.8297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577088PMC
February 2018
11 Reads

Multicentric reticulohistiocytosis associated with thymic carcinoma.

Rheumatology (Oxford) 2017 Oct;56(10):1706

Department of Internal Medicine, Maricopa Medical Center.

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http://dx.doi.org/10.1093/rheumatology/kex224DOI Listing
October 2017
12 Reads

Looks Can Be Deceiving: A Case Report on Multicentric Reticulohistiocytosis Successfully Treated with Rituximab.

Cureus 2017 May 3;9(5):e1220. Epub 2017 May 3.

Rheumatology, Orlando VA Medical Center.

Multicentric reticulohistiocytosis (MRH) is an idiopathic multisystemic inflammatory disease characterized by symmetric erosive polyarthritis and typical papulonodular skin lesions. MRH can be associated with autoimmune diseases, malignancy, mycobacterial infections, and hyperlipidemia, and it is important to consider appropriate screening in this population. There is no specific diagnostic laboratory test for MRH. Read More

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http://dx.doi.org/10.7759/cureus.1220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453733PMC
May 2017
36 Reads

Involvement of M2 macrophages in the pathomechanisms of multicentric reticulohistiocytosis.

Int J Dermatol 2017 08 29;56(8):e173-e175. Epub 2017 May 29.

Department of Dermatology, Jichi Medical University, Shimotsuke, Japan.

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http://dx.doi.org/10.1111/ijd.13661DOI Listing
August 2017
11 Reads

Dermoscopic features of periungual papules in multicentric reticulohistiocytosis.

J Eur Acad Dermatol Venereol 2017 Oct 30;31(10):e442-e443. Epub 2017 May 30.

Department of Dermatology, Venereology and Allergology, Medical University of Gdansk, Kliniczna 1a Street, 80-402, Gdańsk, Poland.

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http://doi.wiley.com/10.1111/jdv.14260
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http://dx.doi.org/10.1111/jdv.14260DOI Listing
October 2017
15 Reads

Multiple cutaneous reticulohistiocytosis with T-cell large granular lymphocyte clonopathy.

Australas J Dermatol 2017 Nov 4;58(4):e249-e252. Epub 2017 Apr 4.

Department of Dermatology, University General Hospital of Heraklion, Heraklion, Crete, Greece.

A 63-year-old Caucasian man presented with a 4-month history of disseminated asymptomatic reddish-brown papulonodular lesions. A skin biopsy showed dermal infiltration with CD68 histiocytes, predominantly with eosinophilic cytoplasm, some with a ground-glass cytoplasm, and a small number of giant cells. The diagnosis of multiple cutaneous reticulohistiocytosis was made. Read More

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http://dx.doi.org/10.1111/ajd.12608DOI Listing
November 2017
11 Reads

Multicentric Reticulohistiocytosis Mimicking Malignancy on 18F-FDG PET/CT.

Clin Nucl Med 2017 Jul;42(7):567-568

From the Departments of *Nuclear Medicine, †Dermatology, and ‡Urology, National Center for Global Health and Medicine, Tokyo, Japan.

We report the case of a 75-year-old woman who underwent F-FDG PET/CT to evaluate the recurrence of urothelial carcinoma. PET/CT showed F-FDG-avid muscles and lymph nodes, mimicking recurrence. However, F-FDG uptake was also seen in multiple joints and subcutaneous tissue, representing an uncommon finding for recurrence. Read More

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http://dx.doi.org/10.1097/RLU.0000000000001661DOI Listing
July 2017
11 Reads

Multicentric reticulohistiocytosis: Rheumatology perspective.

Best Pract Res Clin Rheumatol 2016 04 1;30(2):250-260. Epub 2016 Oct 1.

Department of Internal Medicine, Division of Rheumatology, Istanbul Faculty of Medicine, Istanbul, Turkey. Electronic address:

Multicentric reticulohistiocytosis (MRH) is a rare, multisystemic non-Langerhans cell histiocytosis characterized by skin and articular involvement, and rarely involves various other organs. There are no specific laboratory findings for MRH. Diagnosis is based on clinical findings and skin or synovial biopsy results. Read More

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http://dx.doi.org/10.1016/j.berh.2016.07.002DOI Listing
April 2016
14 Reads

[Acid sphingomyelinase deficiency (Niemann-Pick disease type B) in adulthood: A retrospective multicentric study of 28 adult cases].

Rev Med Interne 2017 May 22;38(5):291-299. Epub 2016 Nov 22.

Service de médecine interne-rhumatologie, groupe hospitalier Diaconesses-Croix-Saint-Simon, 125, rue d'Avron, 75020 Paris, France.

Introduction: Acid sphingomyelinase deficiency (ASMD) is an autosomal recessive disease with a clinical spectrum ranging from a neurovisceral infantile form (Niemann-Pick disease type A) to a chronic visceral form also encountered in adults (Niemann-Pick disease type B, NP-B).

Methods: Retrospective multicentric analysis of French adult patients with ASMD over the period 1985-March 2015. Clinical, biological, and imaging data were analyzed. Read More

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http://dx.doi.org/10.1016/j.revmed.2016.10.387DOI Listing
May 2017
9 Reads

Multicentric Reticulohistiocytosis: an Unknown Source of Embolic Stroke.

J Stroke Cerebrovasc Dis 2017 Jan 11;26(1):e22-e24. Epub 2016 Nov 11.

Department of Neurology, University of California, Los Angeles, California.

Multicentric reticulohistiocytosis (MRH) is a rare inflammatory disorder that presents with diverse systemic infiltrative manifestations. We report the first case of biopsy-proven MRH that presented with acute ischemic stroke in an embolic pattern. We discuss the clinical presentation, imaging findings, and diagnostic approach in our case. Read More

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2016.10.023DOI Listing
January 2017
10 Reads

Multicentric Reticulohistiocytosis: A Unique Case of Chronic Colitis.

Am J Gastroenterol 2016 Sep;111(9):1227

Medical Faculty, University of Tuzla, Tuzla, Bosnia and Herzegovina.

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http://dx.doi.org/10.1038/ajg.2016.150DOI Listing
September 2016
11 Reads
10.760 Impact Factor

Multicentric Reticulohistiocytosis in a 5-Year-Old Girl.

J Pediatr 2016 Oct 1;177:328-328.e1. Epub 2016 Aug 1.

Department of Dermatology Section of Dermatopathology Medical College of Wisconsin Milwaukee, Wisconsin.

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http://dx.doi.org/10.1016/j.jpeds.2016.06.090DOI Listing
October 2016
21 Reads

Metastatic Inflammatory Breast Cancer Associated With Multicentric Reticulohistiocytosis Successfully Treated With Zoledronic Acid.

Clin Breast Cancer 2016 12 25;16(6):e203-e207. Epub 2016 Jun 25.

Neag Comprehensive Cancer Center, UConn Health, Farmington, CT.

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http://dx.doi.org/10.1016/j.clbc.2016.06.011DOI Listing
December 2016
22 Reads

Adult onset hemophagocytic lymphohistiocytosis prognosis is affected by underlying disease and coexisting viral infection: analysis of a single institution series of 35 patients.

Hematol Oncol 2017 Dec 3;35(4):828-834. Epub 2016 Jun 3.

Hematology, Spedali Civili, Brescia, Italy.

Adult onset hemophagocytic lymphohistiocytosis (HLH) is a hyperinflammatory syndrome, which can develop as a complication of many disorders. Early diagnosis is essential in order to avoid a fatal outcome. To confirm the diagnosis of acquired HLH made in a single institution series of adult patients with HLH-04 criteria, we applied the HScore and evaluated prognostic factors associated with clinical outcome. Read More

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http://dx.doi.org/10.1002/hon.2314DOI Listing
December 2017
17 Reads

Nailfold Capillary Patterns in a Patient With Multicentric Reticulohistiocytosis and Raynaud Phenomenon.

J Clin Rheumatol 2016 Jun;22(4):220-1

From the *Servei de Reumatologia and †Servei de Dermatologia; and Hospital Moisès Broggi (CSI), Sant Joan Despí, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1097/RHU.0000000000000270DOI Listing
June 2016
15 Reads

Efficacy of Vinblastine and Prednisone in Multicentric Reticulohistiocytosis With Onset in Infancy.

Pediatrics 2016 06;137(6)

Pediatrics, and.

Multicentric reticulohistiocytosis (MRH) is a rare histiocytic proliferative disorder of uncertain etiology, characterized by mucocutaneous papulonodular lesions and progressive, symmetric erosive arthritis. MRH can coexist with various autoimmune disorders, tuberculosis, and malignancy. It usually occurs in the elderly and is very rare in children. Read More

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http://dx.doi.org/10.1542/peds.2015-2118DOI Listing
June 2016
9 Reads

The cutaneous manifestations of gastrointestinal malignancy.

Semin Oncol 2016 06 23;43(3):341-6. Epub 2016 Feb 23.

University of Louisville Division of Dermatology, Louisville, KY. Electronic address:

The skin is often the herald of an underlying systemic illness, and gastrointestinal malignancies can present in numerous ways in the skin. Paraneoplastic phenomenon, such as acanthosis nigricans and tripe palm, may be the first indicator of a gastrointestinal malignancy. In addition, gastrointestinal cancers can metastasize to the skin, as described in the well-known Sister Mary Joseph's nodule. Read More

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http://dx.doi.org/10.1053/j.seminoncol.2016.02.028DOI Listing
June 2016
11 Reads

Cutaneous manifestations of breast cancer.

Authors:
Antoinette R Tan

Semin Oncol 2016 06 23;43(3):331-4. Epub 2016 Feb 23.

Levine Cancer Institute, Carolinas HealthCare System, Charlotte, NC. Electronic address:

Breast cancer may present with cutaneous symptoms. The skin manifestations of breast cancer are varied. Some of the more common clinical presentations of metastatic cutaneous lesions from breast cancer will be described. Read More

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http://dx.doi.org/10.1053/j.seminoncol.2016.02.030DOI Listing
June 2016
14 Reads

Tumor necrosis factor antagonists in the treatment of multicentric reticulohistiocytosis: Current clinical evidence.

Mol Med Rep 2016 Jul 12;14(1):209-17. Epub 2016 May 12.

Department of Rheumatology and Immunology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, P.R. China.

Multicentric reticulohistiocytosis (MRH) is a rare and debilitating systemic disorder characterized by cutaneous nodules and destructive polyarthritis. Due to its unknown etiology, the treatment of MRH varies with different rates of success, which causes treatment options to be rather independent and empirical. In the present study, a case of a 48‑year‑old woman with a 12‑month history of polyarthralgia and skin nodules was reported. Read More

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http://dx.doi.org/10.3892/mmr.2016.5253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918541PMC
July 2016
19 Reads

Multicentric reticulohistiocytosis (MRH): case report with review of literature between 1991 and 2014 with in depth analysis of various treatment regimens and outcomes.

Springerplus 2016 25;5:180. Epub 2016 Feb 25.

Department of Histopathology, AFIP (Armed Forces Institute of Pathology) , Rawalpindi, Pakistan.

Multicentric reticulohistiocytosis is a rare disease affecting skin and joints primarily and rarely other organs. We present a case report of this disease and an extensive review of the literature. We reviewed the data between 1991 and 2014 and extracted 52 individual cases. Read More

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http://dx.doi.org/10.1186/s40064-016-1874-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766148PMC
March 2016
18 Reads

Multiple Cutaneous Reticulohistiocytoma.

Indian J Dermatol 2016 Jan-Feb;61(1):121

Department of Dermatology, Mahatma Gandhi Mission Hospital, Navi Mumbai, Maharashtra, India.

Multicentric reticulohistiocytosis is a rare non-Langerhans cell histiocytosis characterized in its full form by severe destructive arthritis, cutaneous nodules, and systemic manifestations. Cutaneous lesions may precede, accompany, or more commonly develop later than other features in this disease. We describe a case of multiple cutaneous reticulohistiocytoma without any systemic associations after thorough investigations. Read More

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http://dx.doi.org/10.4103/0019-5154.174130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763648PMC
March 2016
9 Reads

Extranodal Rosai-Dorfman Disease: Clinicopathologic Series of 10 Patients With Radiologic Correlation and Review of the Literature.

Am J Clin Pathol 2016 Feb 23;145(2):211-21. Epub 2016 Jan 23.

From the Departments of Pathology and.

Objectives: To describe the radiologic and clinicopathologic features of extranodal Rosai-Dorfman disease (RDD) in our patient population.

Methods: Via a data mining engine, we evaluated 13 cases of extranodal RDD in 10 patients treated at our institution from 2000 to 2014.

Results: There was a marked female predominance (90%) in our series. Read More

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http://dx.doi.org/10.1093/ajcp/aqv029DOI Listing
February 2016
6 Reads

Cerebral and Cutaneous Involvements of Xanthoma Disseminatum Successfully Treated with an Interleukin-1 Receptor Antagonist: A Case Report and Minireview.

Dermatology 2016 8;232(2):171-6. Epub 2016 Jan 8.

Departamento de Neurologx00ED;a, Clx00ED;nica Las Condes, Santiago, Chile.

A young male presented with panhypopituitarism (including diabetes insipidus) and temporal lobe epilepsy. A histology specimen of cutaneous papules was diagnostic of non-Langerhans histiocytosis. The diagnosis of xanthoma granulomata was considered based on the clinical and brain MRI findings. Read More

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http://dx.doi.org/10.1159/000442522DOI Listing
January 2017
25 Reads

Organizing pneumonia associated with multicentric reticulohistiocytosis.

Respirol Case Rep 2015 Dec 15;3(4):125-7. Epub 2015 Sep 15.

Department of Respiratory Medicine Iwata City Hospital Iwata Japan.

Organizing pneumonia (OP) is a clinicopathological entity that occurs idiopathically or in association with several conditions such as connective tissue diseases. Multicentric reticulohistiocytosis (MRH) is a systemic disease characterized by polyarthritis and mucocutaneous lesions, but lung involvement is uncommon. We report a patient with MRH associated with OP. Read More

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http://dx.doi.org/10.1002/rcr2.125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694604PMC
December 2015
9 Reads

Cytokine and viral load kinetics in human herpesvirus 8-associated multicentric Castleman's disease complicated by hemophagocytic lymphohistiocytosis.

Int J Hematol 2016 Apr 21;103(4):469-72. Epub 2015 Dec 21.

Section of Clinical Immunology, Department of Internal Medicine, Erasmus University MC, University Medical Center, Room D-419, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.

Human herpes virus 8 (HHV-8)-associated secondary hemophagocytic lymphohistiocytosis is a rare but critical immuno-hematological entity in immunocompetent patients. Establishing a diagnosis is challenging as is the monitoring of disease activity and therapeutic effects. We report a case of a HHV-8-associated hemophagocytic lymphohistiocytosis in a HIV-negative adult patient with multicentric Castleman's disease. Read More

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http://dx.doi.org/10.1007/s12185-015-1928-4DOI Listing
April 2016
13 Reads

Successful treatment of FKBP51-expressed multicentric reticulohistiocytosis using combination therapy with low-dose denosumab and tacrolimus.

Authors:
S Mokuda H Oiwa

Scand J Rheumatol 2016 14;45(3):247-9. Epub 2015 Dec 14.

a Department of Rheumatology , Hiroshima City Hiroshima Citizens Hospital , Hiroshima , Japan.

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http://dx.doi.org/10.3109/03009742.2015.1110199DOI Listing
August 2016
51 Reads

Bilateral Total Hip Arthroplasty in a Rare Case of Multicentric Reticulohistiocytosis.

Clin Orthop Surg 2015 Dec 13;7(4):509-14. Epub 2015 Nov 13.

Department of Pathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Multicentric reticulohistiocytosis (MRH) is a rare systemic disease, which commonly manifests as muco-cutaneous papulonodules and inflammatory erosive polyarthropathy. In this research, we report the clinical manifestations and management of a rare case of MRH with destructive arthropathy of bilateral hip joints and arthritis mutilans presenting with characteristic deformities. Disabling hip arthropathy that occurs secondary to MRH can be successfully managed with bilateral total hip arthroplasty (THA). Read More

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http://dx.doi.org/10.4055/cios.2015.7.4.509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667121PMC
December 2015
11 Reads

18F-FDG PET/CT Findings in Multicentric Reticulohistiocytosis.

Clin Nucl Med 2016 Apr;41(4):333-5

From the Departments of *Nuclear Medicine, and †Dermatology, First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.

Multicentric reticulohistiocytosis is a rare systemic inflammatory disease of unknown etiology characterized by the infiltration of histiocytes and multinucleated giant cells into multiple systems. The definitive diagnosis depends on biopsy of the affected tissues. Here, we report the F-FDG PET/CT findings of a 62-year-old man with multicentric reticulohistiocytosis. Read More

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http://dx.doi.org/10.1097/RLU.0000000000001071DOI Listing
April 2016
11 Reads

Adult Xanthogranuloma, Reticulohistiocytosis, and Rosai-Dorfman Disease.

Dermatol Clin 2015 Jul;33(3):465-72; discussion 473

Department of Dermatology, UCSF, 1701 Divisadero Street, San Francisco, CA 94115, USA. Electronic address:

Adult xanthogranuloma presents most commonly as an orange-tan firm solitary nodule with no systemic manifestations. Recently, some cases have been reported in conjunction with lymphoproliferative disorders. Adult reticulohistiocytosis classically presents as red to yellow-red dermal nodules. Read More

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http://dx.doi.org/10.1016/j.det.2015.03.011DOI Listing
July 2015
9 Reads

Fatal Outcome of Multiple Clinical Presentations of Human Herpesvirus 8-related Disease After Solid Organ Transplantation.

Transplantation 2016 Jan;100(1):134-40

1 Institute of Pathology, University Hospital (CHUV), Lausanne, Switzerland. 2 Institute of Microbiology, University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland. 3 Infectious Diseases Service, University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland. 4 Transplantation Center, University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland.

Kaposi sarcoma is the most common human herpesvirus 8 (HHV-8)-related disease described after solid organ transplantation. Multicentric Castleman disease and hemophagocytic syndrome are other potential HHV-8-induced entities but are less frequently reported. We describe the case of a liver transplant recipient who presented with an acute febrile illness 1 year after transplantation with a rapidly fatal outcome. Read More

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http://pdfs.journals.lww.com/transplantjournal/9000/00000/Fa
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http://dx.doi.org/10.1097/TP.0000000000000801DOI Listing
January 2016
10 Reads

Successful Treatment of Multicentric Reticulohistiocytosis with Adalimumab, Prednisolone and Methotrexate.

Acta Derm Venereol 2016 Jan;96(1):124-5

Department of Dermatology, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma 371-8511, Japan.

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http://dx.doi.org/10.2340/00015555-2170DOI Listing
January 2016
7 Reads

Erythema, papules, and arthralgia associated with liver cancer: report of a rare case of multicentric reticulohistiocytosis.

Int J Clin Exp Pathol 2015 1;8(3):3304-7. Epub 2015 Mar 1.

Hubei Huanggang Central Hospital Huanggang 438000, Hubei Province, China.

We report a rare case of multicentric reticulohistiocytosis (MRH) associated with liver carcinoma. A 36-year-old man who had been diagnosed as having liver carcinoma for 2 years presented with a 2-month history of multiple papulonodules on the face, ears, neck, and upper chest, accompanied by progressive polyarthralgia of the hands, wrists, elbows and knee joints without fever or chills. Skin histology revealed well defined dermal infiltrate consisting of multinucleated giant cells and macrophages having abundant eosinophilic finely granular cytoplasm with ground glass appearance. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440166PMC
March 2016
13 Reads