4,307 results match your criteria Mucormycosis


Case report: Disseminated pulmonary mucormycosis involving spleen in diabetic patient with aggressive surgical approach.

Int J Surg Case Rep 2018 Nov 29;54:42-46. Epub 2018 Nov 29.

Department of General Surgery, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.

Introduction: Mucormycosis is a life threatening fungal infection that occurs in immunocompromised patients.

Presentation Of Case: A 36-year-old Saudi male with known case of Insulin-Dependent Diabetes Mellitus (IDDM), who was presented with productive cough and diarrhea. Computed tomography (CT) revealed a disseminated fungal invasion of the lungs and spleen with invading the fundus of the stomach. Read More

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November 2018

An Unusual Case of Pulmonary Mucormycosis.

Transplant Proc 2018 Jun 6. Epub 2018 Jun 6.

Alice Springs Hospital, Northern Territory, Australia.

Invasive fungal infections in solid organ transplant recipients are associated with significant morbidity and mortality. Of these fungal infections, mucormycosis presents as an aggressive, frequently fatal angioinvasive infection. Immunocompromised hosts and diabetes are important risk factors. Read More

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Outcomes and factors affecting them in patients with rhino-orbito-cerebral mucormycosis.

Br J Ophthalmol 2018 Dec 4. Epub 2018 Dec 4.

Eye Research Center, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.

Aim: To report the frequency and factors affecting patients', globe and vision survivals in rhino-orbito-cerebral mucormycosis (ROCM).

Methods: This is a retrospective study of 63 patients (79 eyes) with biopsy-proven ROCM at a university hospital 2008-2016. Systemic and ophthalmic manifestations, imaging, management and final outcomes were recorded. Read More

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December 2018

Posaconazole and isavuconazole induced hypomagnesaemia.

Med Mycol Case Rep 2019 Mar 28;23:29-30. Epub 2018 Sep 28.

Department of Infectious Diseases & Microbiology, Royal Prince Alfred Hospital, Missenden Road, Camperdown, NSW, Australia.

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[The treatment of mucormycosis (zygomycosis) in the 21st century].

Rev Iberoam Micol 2018 Nov 21. Epub 2018 Nov 21.

Unidad de Enfermedades Infecciosas, Hospital Universitario y Politécnico La Fe, Valencia, España. Electronic address:

Infections due to zygomycetes, caused by mucorales and entomophthorales, are characterized by angioinvasion and invasion of neighboring organs or structures. Mucorales most commonly cause rhinocerebral, pulmonary, cutaneous or disseminated infection and its spread is favored by several diseases (such as diabetes or chronic kidney disease) and risk factors (neutropenia, immunosuppression, iron overload). They have a high mortality rate, and the key to success in their treatment are early diagnosis, prompt administration of antifungal treatment, and extensive surgical debridement. Read More

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November 2018
2 Reads

[Invasive aspergillosis in solid organ transplantation].

Rev Iberoam Micol 2018 Nov 19. Epub 2018 Nov 19.

Unidad de Enfermedades Infecciosas, Instituto de Investigación Hospital Universitario 12 de Octubre (i+12), Hospital Universitario 12 de Octubre, Universidad Complutense, Madrid, España. Electronic address:

Solid organ transplant (SOT) recipients have a high risk for developing invasive fungal infections (IFI). Treatment is difficult due to the interaction between the antifungal and immunosuppressant drugs, as well as the risk of hepatotoxicity and kidney failure associated with voriconazole and amphotericinB, respectively. Isavuconazole is a new antifungal triazole agent with excellent oral bioavailability, predictable and linear pharmacokinetics, good tolerance and low adverse effects. Read More

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November 2018
2 Reads

[Epidemiology of invasive mycoses: A landscape in continuous change].

Rev Iberoam Micol 2018 Nov 19. Epub 2018 Nov 19.

Departamento de Inmunología, Microbiología y Parasitología, Facultad de Medicina y Enfermería, Universidad del País Vasco/Euskal Herriko Unibertsitatea (UPV/EHU), Bilbao, España. Electronic address:

The landscape of invasive mycoses is in a continuous evolution with important implications for their diagnosis and treatment. The overall burden remains high, particularly in neonates and the elderly, patients admitted to intensive care units, using prostheses, catheters or other intravenous devices, those receiving different immunosuppressant treatments or antineoplastic chemotherapy, or transplant recipients. In addition, opportunistic mycoses can be associated with HIV infection. Read More

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November 2018
2 Reads

Isavuconazole: Case Report and Pharmacokinetic Considerations.

Chemotherapy 2018 11 20;63(5):253-256. Epub 2018 Nov 20.

Clinical Pharmacology Unit, University Hospital Campus Bio-Medico of Rome, Rome,

Invasive fungal disease (IFD) is one of the major causes of morbidity and mortality in immunocompromised patients. Voriconazole (VCZ) and posaconazole (PCZ) remain the most widely used antifungals for the prophylaxis and treatment of IFD. However, VCZ and PCZ are liable for drug-drug interactions and show a pharmacokinetic variability that requires therapeutic drug monitoring (TDM). Read More

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November 2018
3 Reads

Pre-Exposure to Isavuconazole Increases the Virulence of Mucorales but not in a Infection Model.

Antimicrob Agents Chemother 2018 Nov 19. Epub 2018 Nov 19.

Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M.D. Anderson Cancer Center, Houston, Texas., U.S.A

Breakthrough mucormycosis in patients receiving isavuconazole prophylaxis or therapy has been reported. We compared the impact of isavuconazole and voriconazole exposure on the virulence of clinical isolates of and different Mucorales species in a infection model. In contrast to , a hyper-virulent phenotype was found in all tested Mucorales upon pre-exposure to either voriconazole or isavuconazole. Read More

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November 2018
4 Reads

Prosthetic rehabilitation of resected orbit in a case of mucormycosis.

J Indian Prosthodont Soc 2018 Oct-Dec;18(4):364-369

Senior Research Associate, Maulana Azad Institute of Dental Sciences, New Delhi, India.

The design of orbital prosthesis to rehabilitate patients with orbital exenteration depends on the underlying clinical condition, material chosen for prosthesis, method of retention of the prosthesis, and and preference of the patient. Rehabilitation of a patient with orbital exenteration due to mucormycosis has been described by fabricating a prosthesis that used polymethyl methacrylate (to fabricate a conformer) and silicone material (to fabricate prosthetic superstructure). The two-component prosthesis was designed to attain dual mechanical retention using an anatomic undercut (conformer) and manually created mechanical undercut (prosthetic superstructure). Read More

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February 2018
2 Reads

Severe Neuropathic Pain With Concomitant Administration of Vincristine and Posaconazole.

J Pediatr Pharmacol Ther 2018 Sep-Oct;23(5):417-420

Vincristine is a chemotherapeutic agent with a potential toxicity of sensorimotor peripheral neuropathy. Patients receiving chemotherapy are in an immunocompromised state and may require antifungal agents. Triazole antifungals are known inhibitors of cytochrome P450 (CYP) enzymes. Read More

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November 2018
4 Reads

Comparing the profile of respiratory fungal pathogens amongst immunocompetent and immunocompromised hosts, their susceptibility pattern and correlation of various opportunistic respiratory fungal infections and their progression in relation to the CD4+T-cell counts.

Indian J Med Microbiol 2018 Jul-Sep;36(3):408-415

Department of Microbiology, JNMC, AMU, Aligarh, Uttar Pradesh, India.

Introduction: Invasive fungal infections are increasingly common in the nosocomial setting.

Materials And Methods: The patients were divided into two groups immunocompetent and immunocompromised that is, patients with significant neutropenia <500 neutrophils/μl for longer than 10 days. microscopy, culture, identification of isolates were done and some specilised tests on serum and BAL for antigen detection were performed. Read More

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November 2018
3 Reads

Treatment of cerebral mucormycosis with drug therapy alone: A case report.

Med Mycol Case Rep 2019 Mar 28;23:4-7. Epub 2018 Oct 28.

Infectious Diseases Unit, Prince Sultan Military Medical City (PSMMC), Riyadh, Saudi Arabia.

We report on an elderly male patient with headache and right-side weakness. Imaging studies revealed multiple space-occupying lesions in the parietal and occipital cerebral regions. Biopsy revealed broad aseptate ribbon-like structures branching at right angles, suggestive of mucormycosis. Read More

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March 2019
3 Reads

Healthcare Burden of Probable and Proven Invasive Mucormycosis: A Multicenter Cost-of-Illness Analysis of Patients Treated in Tertiary Care Hospitals between 2003 - 2016.

J Hosp Infect 2018 Nov 10. Epub 2018 Nov 10.

University Hospital of Cologne, Department I of Internal Medicine, Cologne, Germany; German Centre for Infection Research, Partner Site Bonn-Cologne, Cologne, Germany.

Background: Invasive mucormycosis (IM) is a rare invasive fungal infection with high mortality rates. However, data concerning the clinical and economic burden of IM are scarce.

Aim: To evaluate the direct treatment costs and additional expenditures of patients with IM. Read More

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November 2018
9 Reads

Diagnosis and Treatment of Isolated Cerebral Mucormycosis: Patient-Level Data Meta-Analysis and Mayo Clinic Experience.

World Neurosurg 2018 Nov 8. Epub 2018 Nov 8.

Neurology, Mayo Clinic Health System-Franciscan Healthcare in La Crosse, La Crosse, Wisconsin.

Isolated cerebral mucormycosis is a rare and serious infection associated with intravenous drug abuse We provide a comprehensive meta-analysis of reported cases in the literature and an unpublished case from our institution. We searched PubMed/Medline, EMBASE, Scopus, Cochrane Databases, and our institution's electronic health records from inception through March 31, 2018. Cases were considered isolated (only affecting the cerebrum, cerebellum, or brainstem) if documentation existed for the absence of other primary sources of infection. Read More

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November 2018
1 Read
2.420 Impact Factor

Isolated renal mucormycosis in a patient with Idiopathic CD4 lymphocytopenia.

BMJ Case Rep 2018 Nov 8;2018. Epub 2018 Nov 8.

Department of Nephrology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Idiopathic CD4 lymphocytopenia (ICL) is characterised by a low CD4 +lymphocyte count in the absence of HIV or other underlying aetiologies. We report a case of a 17-year-old girl with ICL with autoimmune hepatitis who developed isolated renal mucormycosis, which, to our knowledge, is the first reported case described in literature. Combination therapy with antifungals and surgical resection was done, and the patient improved. Read More

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November 2018
8 Reads

Surgery for Pulmonary Fungal Infections Complicating Hematological Malignancies.

Korean J Thorac Cardiovasc Surg 2018 Oct 5;51(5):350-355. Epub 2018 Oct 5.

Department of General Thoracic Surgery, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital.

Background: The complication rate of fungal disease is higher among patients with hematological malignancies. We investigated the clinicobacteriological outcomes of resected pulmonary fungal infections complicating hematological malignancies.

Methods: Between 2001 and 2017, 21 patients with pulmonary fungal infections complicating hematological malignancies underwent resection, and their clinical records and survival were retrospectively reviewed. Read More

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October 2018
5 Reads

Treating mucormycosis using a multimodality approach: a case series.

J Wound Care 2018 Nov;27(11):735-742

Dr, Consultant (Plastic Surgery), Sir Ganga Ram Hospital, New Delhi.

Most fungal infections found in wounds are secondary or superadded, and are generally benign in their clinical course in healthy individuals, with the exception of mucormycosis. This is a life-threatening infection caused by fungi of the order Mucorales. Primary cutaneous disease may occur following traumatic implantation of spores, or use of contaminated bandages, or as a complication of extensive burns, diabetic acidosis and other specific immunocompromised conditions. Read More

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November 2018
6 Reads

Successfull treatment of S osteomyelitis by conservative surgery and intra-diaphysal incorporation of amphotericin B cement beads.

Antimicrob Agents Chemother 2018 Oct 29. Epub 2018 Oct 29.

Infectious Diseases and Tropical Medicine Department, Necker Pasteur Infectious Diseases Centre, Necker-Enfants Malades Hospital, APHP, Institut Hospitalo-Universitaire Imagine, Paris Descartes University, Paris, France.

Osteoarticular mucormycosis are quite rare and challenging infections mostly due to direct inoculation during traumatic injury in immunocompetent patients. Their classical management includes a combination of aggressive surgical debridement that may lead to amputation and long-term systemic liposomal amphotericin B therapy. This article describes successful treatment of a osteomyelitis in a patient with diabetes mellitus with a combination of systemic antifungal agents and a conservative surgery with insertion of amphotericin-impregnated cement beads. Read More

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October 2018
5 Reads

Primary Cutaneous Mucormycosis in a Beta-Thalassemia Patient.

Indian J Hematol Blood Transfus 2018 Oct 26;34(4):776-777. Epub 2018 Apr 26.

1Molecular Dermatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

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October 2018
1 Read
0.230 Impact Factor

Deferiprone as adjunctive treatment for patients with invasive mucormycosis: A retrospective case series.

Infect Dis Rep 2018 Sep 25;10(2):7765. Epub 2018 Sep 25.

Division of Hematology, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Mucormycosis is a life-threatening disease requiring multimodal treatment with antifungals and surgery. The mortality rate remains high, prompting consideration of alternative treatment strategies. Deferiprone has activity against , but its efficacy has never been evaluated in humans. Read More

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September 2018
5 Reads

Infection due to Saksenaea vasiformis Following a Spider Bite.

J Hand Surg Am 2018 Oct 18. Epub 2018 Oct 18.

Orthopaedic and Trauma Department, Complutense University of Madrid, Madrid, Spain; School of Medicine, Complutense University of Madrid, Madrid, Spain.

Cutaneous mucormycosis due to Saksenaea vasiformis species is exceptional. There have been about 40 reported cases worldwide, with most being fatal. We report an exceptional nonlethal case of mucormycosis due to S. Read More

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October 2018

Invasive mucormycosis in children with cancer: A retrospective study from the Infection Working Group of Italian Pediatric Hematology Oncology Association.

Mycoses 2018 Oct 18. Epub 2018 Oct 18.

Pediatric Hematology Oncology, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.

Background: Invasive mucormycosis is a rare but frequently fatal fungal disease. The acute and rapidly progressive evolution causes unfavourable outcome in 22%-59% of patients and its treatment represents a clinical challenge, especially in immunocompromised patients. Current data in paediatric oncological patients are limited. Read More

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October 2018
3 Reads
1.800 Impact Factor

Retrobulbar optic neuropathy associated with sphenoid sinus mucormycosis.

Neurol Clin Neurosci 2018 Sep 10;6(5):146-147. Epub 2018 Jul 10.

Department of Neurology JA Toride Medical Center Toride Ibaraki Japan.

Because fungi usually spread from the paranasal sinuses to the orbital apex in invasive fungal sinusitis (IFS), IFS often presents as an orbital apex syndrome (OAS) characterized by dysfunction of cranial nerves II, III, IV, V1, and VI. We report a case of sphenoid sinus mucormycosis that presented as isolated retrobulbar optic neuropathy. A 94-year-old woman presented with acute blindness in the right eye. Read More

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September 2018
1 Read

Ophtalmoplegia complicating sino-orbital mucormycosis.

Tunis Med 2018 Mar;96(3):224-226

Purpose: To report a case of complete ophthalmoplegia and blindness in sino-orbital mucormycosis.

Case Report: A 68-year-old woman with history of diabetes and breast cancer presented with sudden onset of fever, orbital pain and blindness in the right eye. The patient was found to have no light perception, complete ophthalmoplegia, chemosis, corneal ulcer and optic nerve atrophy. Read More

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March 2018
1 Read

Orbitocerebral Mucormycosis in a Patient With Central Nervous System Lymphoma.

Ophthalmic Plast Reconstr Surg 2018 Nov/Dec;34(6):e197-e201

Ruiz Department of Ophthalmology and Visual Science.

A 61-year-old man with well-controlled diabetes mellitus type 2, cirrhosis from hepatitis C, alcohol abuse, and portal hypertension presented with painful vision loss and left orbital swelling. Imaging showed diffuse orbital, perineural, and pachymeningeal inflammation. He was initially diagnosed with neurosarcoidosis. Read More

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November 2019
6 Reads

Vacuum Sealing Drainage Therapy for Refractory Infectious Wound on 16 Renal Transplant Recipients.

Transplant Proc 2018 Oct 12;50(8):2479-2484. Epub 2018 Apr 12.

Organ Transplant Center, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China. Electronic address:

Background: Refractory infectious wounds on renal transplantation (RT) recipients significantly prolong hospital stay, increase medical costs, and threaten allograft survival. Vacuum sealing drainage (VSD) therapy is a new technique for managing wounds based on the principle of application of controlled negative pressure. The aim of this study was to summarize the efficacy and safety of VSD therapy in the management of refractory infectious wounds following RT. Read More

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October 2018
5 Reads

Advances in the Treatment of Mycoses in Pediatric Patients.

J Fungi (Basel) 2018 Oct 11;4(4). Epub 2018 Oct 11.

Infectious Diseases Unit, 3rd Department of Pediatrics, Faculty of Medicine, Aristotle University School of Health Sciences, Konstantinoupoleos 49, 54642, Thessaloniki, Greece.

The main indications for antifungal drug administration in pediatrics are reviewed as well as an update of the data of antifungal agents and antifungal policies performed. Specifically, antifungal therapy in three main areas is updated as follows: a) Prophylaxis of premature neonates against invasive candidiasis; b) management of candidemia and meningoencephalitis in neonates; and c) prophylaxis, empiric therapy, and targeted antifungal therapy in children with primary or secondary immunodeficiencies. Fluconazole remains the most frequent antifungal prophylactic agent given to high-risk neonates and children. Read More

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October 2018

Isavuconazole Kinetic Exploration for Clinical Practice.

Drugs R D 2018 Dec;18(4):317-321

Laboratoire de Pharmacocinétique et Toxicologie, Institut Fédératif de Biologie, 330 Avenue Grande Bretagne, 31059, Toulouse Cedex 09, France.

Background: Isavuconazole is a new antifungal prodrug for the treatment of invasive aspergillosis and mucormycosis. As no clear pharmacokinetic-pharmacodynamic relationship has been established for patients, therapeutic drug monitoring is not currently required. However, as isavuconazole is a new drug, clinicians are sometimes sceptical about the exposure achieved in their patients and seek pharmacokinetic exploration. Read More

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December 2018
5 Reads

Invasive rhinocerebral mucormycosis in a patient with liver cirrhosis leading to fatal massive stroke.

Med Mycol Case Rep 2018 Dec 21;22:69-73. Epub 2018 Sep 21.

Hamad Medical Corporation, Al-Sadd, Doha 3050, Qatar.

Immunocompromised status is associated with invasive fungal infections including mucormycosis. These infections are challenging to treat and associated with high overall mortality. Here we report a fatal case of invasive mucormycosis in a cirrhotic, diabetic patient. Read More

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December 2018
6 Reads

Role of Serological Tests in the Diagnosis of Mold Infections.

Curr Fungal Infect Rep 2018 5;12(3):127-136. Epub 2018 Sep 5.

2Division of Infection, Inflammation and Respiratory Medicine, Faculty of Biology, Medcine and Health, The University of Manchester, Manchester, M13 9PL UK.

Purpose Of Review: To understand the role of antibody detection in the diagnosis of infections caused by filamentous fungi (molds). Rapid and accurate profiling of infection-causing fungal pathogens remains a significant challenge in modern health care. Classical fungal culture and serology continue to be relevant even though over the past few decades, antigen (biomarker) assays such as ELISA and lateral flow devices have been developed and validated. Read More

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September 2018
2 Reads

[Clinical features and outcome in patients with mucormycosis in a tertiary hospital (2012-2016)].

Rev Iberoam Micol 2018 Jul - Sep;35(3):162-166. Epub 2018 Sep 28.

Servicio de Enfermedades Infecciosas, Hospital Clínic-IDIBAPS, Universidad de Barcelona, Barcelona, España.

Background: The most common presentation of mucormycosis in the past was the nasosinusal involvement in patients with diabetic ketoacidosis. However, in the last few years, new groups of patients with risk of mucormycosis have emerged.

Aims And Methods: Retrospective analysis of the characteristics, treatment and evolution of patients with mucormycosis in a tertiary hospital in the years 2012-2016. Read More

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September 2018
2 Reads

Recent advances in the understanding and management of mucormycosis.

F1000Res 2018 7;7. Epub 2018 Sep 7.

Paris Descartes University, Sorbonne Paris Cité, Infectious Diseases Unit, Necker-Enfants Malades University Hospital, AP-HP, Imagine Institute, Paris, France.

Mucormycoses were difficult-to-manage infections owing to limited diagnostic tools and therapeutic options. We review here advances in pathology understanding, diagnostic tools including computed tomography, and serum polymerase chain reaction and therapeutic options. Read More

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September 2018
6 Reads

Pathways of Pathogenicity: Transcriptional Stages of Germination in the Fatal Fungal Pathogen .

mSphere 2018 09 26;3(5). Epub 2018 Sep 26.

Institute for Microbiology and Infection, School of Biosciences, University of Birmingham, Birmingham, United Kingdom

is an invasive fungal pathogen responsible for the frequently fatal disease mucormycosis. Germination, a crucial mechanism by which infectious spores of cause disease, is a key developmental process that transforms the dormant spore state into a vegetative one. The molecular mechanisms that underpin this transformation may be key to controlling mucormycosis; however, the regulation of germination remains poorly understood. Read More

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September 2018
4 Reads

Renal Mucormycosis: A Rare Cause of Urinary Tract Infection Leading to End-stage Renal Disease (ESRD).

J Trop Pediatr 2018 Sep 25. Epub 2018 Sep 25.

Division of Pediatric Nephrology and Pediatrics Unit II, Christian Medical College, Vellore, Tamil Nadu, India.

Mucormycosis is a rare fungal infection often seen in immunocompromised hosts. Isolated renal mucormycosis may however present in immunocompetent children as renal failure and has a uniformly poor prognosis if not detected and treated early into the course of illness. We present a 3-year-old boy with unrelenting pyelonephritis in whom serial urine cultures done were negative. Read More

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September 2018
3 Reads

Post-exposure prophylaxis with isavuconazole after occupational exposure to .

Oxf Med Case Reports 2018 Oct 18;2018(10):omy062. Epub 2018 Sep 18.

Division of Infectious Diseases, McGovern Medical School, Houston, TX, USA.

Invasive mucormycosis is typically seen in patients with hematological malignancies, diabetes and other conditions that affect the immune system. However, locally invasive disease can also be seen in both immunocompromised and immunocompetent hosts after trauma and direct inoculation. Since historically post-exposure prophylaxis with lipid-based amphotericin B compounds has not been feasible because of a high toxicity profile, there is no experience regarding the role of post-exposure prophylaxis after injuries contaminated with agents of mucormycosis. Read More

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October 2018

Necrotizing fungal infection due to : A case report and review of literature.

Indian J Ophthalmol 2018 Oct;66(10):1513-1516

Department of Orbit, Oculoplasty, Reconstructive and Aesthetics, Medical Research Foundation, Chennai, Tamil Nadu, India.

Mucormycosis caused by Saksenaea erythrospora is an emerging infection seen with soil contamination, burns and/or nosocomial infections. PCR amplification and internal transcribed spacer sequencing is gold standard for its identification. Here, we report a case of necrotizing fungal orbital infection by S. Read More

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October 2018
6 Reads

Mucormycosis outbreak due to Rhizopus microsporus after arthroscopic anterior cruciate ligament reconstruction surgery evaluated by RAPD and MALDI-TOF Mass spectrometry.

J Mycol Med 2018 Dec 22;28(4):617-622. Epub 2018 Sep 22.

Laboratorio de Micología y Diagnóstico Molecular (CONICET), Cátedra de Parasitología y Micología, Facultad de Bioquímica y Ciencias Biológicas, Ciudad Universitaria, Paraje el Pozo S/N, CP 3000 Santa Fe, Argentina; Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET), CCT, Santa Fe, Argentina. Electronic address:

Background: Rhizopus microsporus is one of the main causative agents of mucormycosis. These mycoses are mostly described as isolated cases involving uncontrolled diabetes mellitus or immunosuppressed patients. In this work we report a nosocomial outbreak of mucormycosis due to R. Read More

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December 2018

A Case of Invasive Gastrointestinal Mycotypha Infection in a Patient with Neutropenia.

Case Rep Infect Dis 2018 2;2018:5864175. Epub 2018 Sep 2.

Division of Infectious Diseases, Department of Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York, USA.

Gastrointestinal mucormycosis is a rare life-threatening infection to which neutropenic patients are especially vulnerable. is a mucormycete that has not been described as a human pathogen. We discuss the successful eradication of gastrointestinal in a neutropenic patient with simultaneous pulmonary infection. Read More

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September 2018
1 Read

Post-traumatic fatal disseminated infection.

Med Mycol Case Rep 2018 Dec 6;22:45-47. Epub 2018 Sep 6.

Department of Infectious Diseases, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA.

Mucorales infections typically occur in immunocompromised hosts. We describe a case of disseminated post-traumatic Apophysomyces elegans in an immunocompetent patient status-post soil inoculation. Fungi introduced at a deep arm laceration leads to neurovascular invasion and dissemination prior to amputation and systemic treatment. Read More

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December 2018

[Clinical high risk factors and prognosis of 25 pulmonary mucormycosis cases].

Zhonghua Yi Xue Za Zhi 2018 Aug;98(32):2579-2582

Department of Respiratory Medicine, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China.

To analyze high risk factors, therapeutic regimen and prognosis of patients with pulmonary mucormycosis. A retrospective analysis was performed on the clinical data of 25 patients who were diagnosed as pulmonary mucormycosis in the First Affiliated Hospital, School of Medicine, Zhejiang University, between January 2009 and December 2017. Univariate analysis revealed that no risk factor had significant effect on prognosis of these 25 cases, while multivariate logistic regression analysis confirmed that the exposure to antifungal drugs was correlated to worse prognosis(=0. Read More

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August 2018
11 Reads

Correction to: Mucormycosis in hospitalized patients at a tertiary care center in Lebanon: a case series.

Infection 2018 Sep 14. Epub 2018 Sep 14.

Division of Infectious Diseases, American University of Beirut Medical Center, Riad El Solh, PO Box 11-0236, Beirut, 1107 2020, Lebanon.

The spelling of the name "Ali Bazarbachi" was incorrect. Read More

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September 2018
1 Read

Cutaneous mucormycosis caused by in a patient with systemic lupus erythematosus.

Clin Case Rep 2018 Sep 13;6(9):1730-1734. Epub 2018 Jul 13.

National Hospital Colombo Sri Lanka.

Primary cutaneous mucormycosis due to is a rare clinical manifestation and the actual number of the disease condition is underestimated due to lack of sporulation in the absence of molecular diagnosis. Combination therapy of antifungal and repetitive debridement is mandatory in curing the patients. Read More

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September 2018
7 Reads

Successful Treatment of Concurrent Mucormycosis and Diffuse Alveolar Hemorrhage in a Patient With Newly Diagnosed Systemic Lupus Erythematosus.

Arch Rheumatol 2018 Jun 15;33(2):244-246. Epub 2018 Jan 15.

Department of Internal Medicine, Division of Rheumatology, Gachon University Gil Medical Center, Incheon, South Korea.

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June 2018
9 Reads

Tongue necrosis secondary to mucormycosis in a diabetic patient: A first case report in Malaysia.

J Mycol Med 2018 Sep 7;28(3):519-522. Epub 2018 Jul 7.

Department of Oral and Maxillofacial Surgery, Hospital Sungai Buloh, Selangor, Malaysia.

Mucormycosis is a rare fungal infection and high mortality that commonly affects patients with the weakened immune system. We present an unusual case of tongue necrosis probably due to the healthcare-associated mucormycosis (HCM) in a diabetic patient. Although cannot be proved with certainty, we surmise that intubation as a risk factor in our case. Read More

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September 2018

Recent advances in the molecular diagnosis of mucormycosis.

Expert Rev Mol Diagn 2018 Oct 19;18(10):845-854. Epub 2018 Sep 19.

b Department of Infectious Diseases, Infection Control and Employee Health , The University of Texas MD Anderson Cancer Center , Houston , TX , USA.

Introduction: Fungal infection burden related to Mucorales has been on the rise with significant associated morbidity and mortality. The major obstacle in the management has been lack of a non-invasive rapid and a reliable diagnostic test. Developing a culture-independent biomarker for the early diagnosis of mucormycosis is a major unmet need in modern mycology. Read More

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October 2018
6 Reads

Pulmonary Campylobacter concisus infection in an immunocompromised patient with underlying mucormycosis.

Int J Infect Dis 2018 Nov 8;76:45-47. Epub 2018 Sep 8.

Institute of Medical Microbiology and Hygiene, University Hospital of Ulm, Albert-Einstein-Allee 23, D-89081 Ulm, Germany.

Campylobacter concisus is a rarely encountered agent of human infection. The first isolation of C. concisus from a pulmonary abscess in an immunocompromised patient who underwent allogeneic stem cell transplantation is reported here. Read More

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November 2018
3 Reads

Mucormycosis Endophthalmitis in a Silicone Oil-Filled Eye of an Immunocompetent Patient.

Ocul Immunol Inflamm 2018 Sep 7:1-3. Epub 2018 Sep 7.

a Advanced Eye Centre , Post Graduate Institute of Medical Education and Research , Chandigarh , India.

Purpose: Fungal endophthalmitis following pars plana vitrectomy with silicone oil tamponade is an infrequent entity. Filamentous fungi like aspergillus are generally associated with endophthalmitis. Mucor is a rarely implicated pathogen in cases of endophthalmitis with only two reported cases in medical literature. Read More

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September 2018

Cutaneous mucormycosis caused by Mucor irregularis in a patient with CARD9 deficiency.

Br J Dermatol 2018 Sep 5. Epub 2018 Sep 5.

Department of Dermatology, Peking University First Hospital, 8 Xishiku Street, Xicheng District, Beijing, 100034, China.

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September 2018