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Ear Nose Throat J 2022 Feb 18:1455613221076784. Epub 2022 Feb 18.

Department of Oral and Maxillofacial Surgery/Orthodontics, 218758Yokohama City University Hospital, Yokohama, Japan.

J Craniofac Surg 2022 Feb 4. Epub 2022 Feb 4.

Department of Oral and Maxillofacial Surgery/Orthodontics, Yokohama City University Hospital, Yokohama, Kanagawa, Japan.

Abstract: Submandibular gland mucoceles, which are very rare cystic lesions, make differentiation from other cystic neck masses such as plunging ranula and cystic lymphatic malformation difficult. The authors report a rare huge submandibular gland mucocele with diagnostic difficulties. A 39-year-old woman with painless swelling in the left submandibular region underwent OK-432 injection therapy with a diagnosis of plunging ranula at another hospital. Read More

Am J Otolaryngol 2022 Jan-Feb;43(1):103276. Epub 2021 Nov 3.

Faculty of Dentistry, Oral and Craniofacial Sciences, King's College London, London, England, UK. Electronic address:

Vet Radiol Ultrasound 2022 Jan 28;63(1):30-37. Epub 2021 Sep 28.

Environmental and Radiological Health Sciences Department, College of Veterinary Medicine and Biomedical Sciences, Fort Collins, Colorado, USA.

Published findings on the computed tomographic (CT) appearance of sialoceles are limited to brief descriptions from reported cases in eight dogs and one cat. The authors have seen sialoceles with CT characteristics that are not consistent with these previous reports. The purpose of this multicenter, retrospective, descriptive, case series study was to provide more detailed descriptions of the CT appearance of confirmed sialoceles in dogs. Read More

J Feline Med Surg 2021 Sep 20:1098612X211046197. Epub 2021 Sep 20.

Eastcott Referrals Veterinary Hospital, Swindon, UK.

Objectives: The aim of this retrospective observational study was to describe the clinical presentation, treatment and outcome of cats with sialocoele.

Methods: Clinical records from seven referral hospitals were retrospectively searched to identify cats with sialocoele between 2007 and 2021.

Results: Nineteen cats were identified. Read More

Otolaryngol Clin North Am 2021 Jun;54(3):543-551

Department of Otolaryngology, University of Pittsburgh Medical Center, Shadyside Hospital, Suite 211, 5200 Centre Avenue, Pittsburgh, PA 15232, USA. Electronic address:

Mucoceles are common salivary gland disorders. Mucoceles are benign, mucus-filled extravasation pseudocysts that commonly arise on the lower lip of children and young adults. Although surgical excision is commonly performed to remove these lesions, other treatments include marsupialization, micromarsupialization laser ablation, cryotherapy, intralesional steroid injection, and sclerosing agents. Read More

Can Vet J 2021 05;62(5):497-500

Zoolife, Via Cavalleggeri Udine, 41, Mezzolombardo, Italy 38017 (Dallago); University of Turin Faculty of Veterinary Medicine, Largo Paolo Braccini, 2, Grugliasco, Italy 10095 (Buracco).

Sialocele is an uncommon condition in cats. The treatment of choice for sublingual sialocele is excision of the ipsilateral mandibular and sublingual salivary gland/duct complex. Lateral and ventral cervical approaches have been described for mandibular-sublingual sialoadenectomy; however, the transoral approach, described here, has never been reported in cats. Read More

Int J Pediatr Otorhinolaryngol 2020 Nov 1;138:110356. Epub 2020 Sep 1.

Department of Otolaryngology-Head and Neck Surgery, Stanford University, Stanford, CA, USA. Electronic address:

Introduction: The diagnosis of ankyloglossia, or tongue-tie, and the number of frenotomies performed has increased over 10-fold from 1997 to 2012 in the United States. The sharpest increase has been in neonates. For parents considering frenotomy for their breastfeeding newborn, there is controversy surrounding the evaluation of tongue-tie and the benefit of a frenotomy. Read More

Int J Oral Maxillofac Surg 2021 Apr 15;50(4):516-521. Epub 2020 Jul 15.

Department of Oral and Maxillofacial Surgery, Qilu Hospital, Institute of Stomatology, Shandong University, Jinan, Shandong Province, PR China. Electronic address:

Mucoceles are common in the minor salivary and sublingual glands. Sclerotherapy is a possible treatment strategy for mucoceles. The purpose of this study was to evaluate the clinical outcomes of sclerotherapy with promethazine hydrochloride injection in treating mucoceles. Read More

Laryngoscope 2021 01 28;131(1):73-77. Epub 2020 Feb 28.

Department of Otolaryngology-Head and Neck Surgery, Manukau Surgery Centre, Counties Manukau District Health Board, Auckland, New Zealand.

Objectives: We present a series of bilateral plunging ranula patients to examine the etiology, diagnosis, treatment, and prognosis of this condition.

Methods: A retrospective chart review was performed on all cases of plunging ranula treated at the Department of Otolaryngology-Head and Neck Surgery, Counties Manukau District Health Board, New Zealand, between 2001 and 2019.

Results: There were 17 patients with bilateral plunging ranulas from a total of 187 plunging ranula patients. Read More

J Korean Assoc Oral Maxillofac Surg 2019 Dec 26;45(6):357-363. Epub 2019 Dec 26.

Department of Oral and Maxillofacial Surgery, College of Dentistry, Wonkwang University, Iksan, Korea.

Ranula is a mucocele caused by extravasation of the sublingual gland on the floor of the mouth. The most common presentation is a cystic mass in the floor of the mouth. A portion of the sublingual gland could herniate through the mylohyoid muscle, and its extravasated mucin can spread along this hiatus into submandibular and submental spaces and cause cervical swelling. Read More

Am J Otolaryngol 2020 Mar - Apr;41(2):102371. Epub 2019 Dec 20.

Department of MaxilloFacial and Oral Surgery, Sefako Makgatho Health Sciences University, P.O. Box D22, Medunsa 0204, South Africa. Electronic address:

Purpose: The aim of this study was to illustrate and confirm that the complete intraoral excision of the sublingual gland alone, is anatomically the most rational approach, for the management of plunging ranula.

Material And Methods: We retrospectively reviewed clinical charts of diagnosed HIV-infected patients presenting with plunging ranula. The intraoral approach was used for the complete excision of the sublingual gland with evacuation of the pseudocystic content only. Read More

Sultan Qaboos Univ Med J 2019 Aug 5;19(3):e257-e261. Epub 2019 Nov 5.

Department of Pathology, Chacha Nehru Bal Chikitsalya, Delhi, India.

Foregut cystic developmental malformations (FCDM) are a type of rare cystic lesion. The occurrence of FCDM is exceedingly uncommon in the intraoral location. We report three cases of FCDM with intraoral location who presented at Chacha Nehru Bal Chikitsalaya, New Delhi, India, in 2016, 2017 and 2018 with symptoms of respiratory distress and feeding difficulties. Read More

Oral Dis 2019 Sep 20;25(6):1664-1667. Epub 2019 Jun 20.

Department of Oral Medicine, Oral and Maxillofacial Surgery, Tokyo Dental College, Chiba, Japan.

Objectives: We hypothesized that the extravasation of saliva from damaged ducts with lymphocytic infiltration in patients with Sjögren's syndrome causes ranulas. There are too many uncertainties to support this hypothesis. The aim of this study was to investigate whether there is an association between Sjögren's syndrome and ranulas. Read More

J Stomatol Oral Maxillofac Surg 2019 Dec 11;120(6):509-512. Epub 2019 Apr 11.

Aix Marseille université, AP-HM, IFSTTAR, LBA, CHU Conception, department of oral and maxillofacial surgery, 13005, Marseille, France.

Introduction: Mucoceles are cystic diseases of the oral mucosa. The most common are ranula and mococeles of the lower lip. Blandin and Nuhn mucoceles, which develop at the ventral side of the tongue, are rare benign lesions. Read More

Ear Nose Throat J 2019 Jun 4;98(5):E21-E23. Epub 2019 Apr 4.

3 Histopathologist, Pathcare, Cape Town, South Africa.

Objective: We report a rare case of an intralingual ranula. The differential diagnosis, etiology, diagnostic features, and management are discussed.

Case Report: An 18-year-old man presented with a mass that extended along the ventral surface of the tongue and up to the tip. Read More

Case Rep Dent 2018 24;2018:3048429. Epub 2018 Apr 24.

Unit of Orthodontics and Paediatric Dentistry, Section of Dentistry, Department of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, Pavia, Italy.

Mucocele (also known as ranula or salivary gland mucous cyst) of the newborn is a lesion present on the intraoral cavity, with the potential to interfere with respiration and feeding. In the present report, a case of mucocele in a 4-month female patient has been described. As conventional surgery can be followed by several complications such as intraoperative bleeding, difficulties in wound healing, and maintenance of sterility during surgery, in the present case, the use of diode laser has been planned. Read More

ANZ J Surg 2018 10 21;88(10):1043-1046. Epub 2017 Dec 21.

Department of Otolaryngology and Head and Neck Surgery, Logan Hospital, Logan City, Queensland, Australia.

Background: Plunging ranulas are rare mucous extravasation pseudocysts that arise in the floor of the mouth and pass into the submandibular space of the neck. The aim of this study was to investigate the diagnosis, surgical management and outcomes of patients with a plunging ranula at our institution in South East Queensland over a 10-year period.

Methods: A retrospective analysis of adult patients diagnosed with and treated for plunging ranula between 2006 and 2016 at Logan Hospital was conducted. Read More

Dentomaxillofac Radiol 2018 May 10;47(4):20170331. Epub 2018 Jan 10.

1 Department of Oral Pathology, Radiology and Medicine,College of Dentistry, The University of Iowa , Iowa City, IA , USA.

Mucoepidermoid carcinoma (MEC) is the most common salivary gland malignancy. The submandibular gland is rarely involved, about less than 10% of all other major salivary glands. We report a case of a 49-year-old female who presented with a mass on the left side of the floor of the mouth. Read More

J Maxillofac Oral Surg 2017 Dec 16;16(4):491-496. Epub 2017 Mar 16.

Department of Oral and Maxillofacial Surgery, AJ Institute of Dental Science and Hospital, Mangalore, Karnataka 575004 India.

Background: This study was undertaken to compare micromarsupialization and modified micromarsupialization for the management of mucoceles.

Materials And Methods: A prospective randomized clinical study was done on thirty patients having mucocele on lower lip. In Group A ( = 15), micromarsupialization and in Group B ( = 15), modified micromarsupialization technique was used. Read More

Oral Surg Oral Med Oral Pathol Oral Radiol 2017 May 22;123(5):e160-e163. Epub 2016 Nov 22.

Division of Oral and Maxillofacial Pathology, Columbia University College of Dental Medicine, New York, NY, USA. Electronic address:

Chronic lymphocytic leukemia (CLL), an indolent neoplasm of B lymphocytes, is the most common adult leukemia in the Western Hemisphere. Despite this, however, the intraoral presentation of CLL is quite rare. We report the case of an 83-year-old woman with CLL incidentally involving minor salivary glands in association with a ranula (floor-of-mouth mucocele). Read More

Niger J Surg 2016 Jul-Dec;22(2):130-133

Department of Oral Medicine and Radiology, Ranchi Institute of Neuro-Psychiatry and Allied Sciences, Kanke, Ranchi, Jharkhand, India.

A mucocele is a common salivary gland disorder that most commonly affects young adults. A 35-year-old female patient reported to the Department of Oral and Maxillofacial Surgery, with the chief complaint of swelling on the left side of floor of mouth. The aim of this case report is to present the management of mucocele present in floor of the mouth in a young female patient using liquid nitrogen cryosurgery. Read More

Br J Oral Maxillofac Surg 2016 Dec 15;54(10):1131-1133. Epub 2016 Apr 15.

Nair Hospital Dental College, Dr. A.L.Nair Road, Opp. Maratha Mandir, Mumbai Central, Mumbai, 400008. Electronic address:

A mucocoele or extravasation of mucus is common in minor salivary glands, but unusual in major ones. Those from the submandibular gland are a diagnostic challenge and conventional management includes excision of the associated gland. We describe a 27-year-old man with a mucocoele of the submandibular gland that presented as a lateral cervical swelling and looked like a plunging ranula. Read More

Braz J Otorhinolaryngol 2016 Sep-Oct;82(5):536-42. Epub 2016 Jan 6.

Universidade Federal do Rio Grande do Norte (UFRN), Natal, RN, Brazil. Electronic address:

Introduction: Mucoceles are common benign pseudocystic lesions of the oral cavity; their main etiological factors are trauma and ductal obstruction. Two histological patterns are found: mucus retention phenomenon (MRP) and mucus extravasation phenomenon (MEP). Mucus extravasation phenomenon is the more common histological subtype and it mainly affects the lower lip. Read More

Stomatologija 2016;18(4):133-136

Department of oral and maxillofacial surgery, Dr. D. Y. Patil school of dentistry, 1, Shanti, Pandloskar marg, Vile Parle (East), Mumbai-400057, India.

A ranula is a large mucocele located in the floor of the mouth. Ranulas is usually a mucous extravasation phenomenon due to injury to sublingual salivary gland. unilateral presentation has been reported in many cases but bilateral presentation and that too in an edentulous patient is quite uncommon. Read More

Oral Maxillofac Surg Clin North Am 2016 Feb;28(1):67-81

Department of Oral and Maxillofacial Surgery, Baltimore College of Dental Surgery, University of Maryland and the Greenbaum Cancer Institute, Suite 1402, 650 W Baltimore Street, Suite 1218, Baltimore, MD 21201, USA.

Salivary gland lesions are rare in pediatric patients. In addition, the types of salivary gland tumors are different in their distribution in specific sites in the major and minor salivary glands in children compared with adults. This article reviews benign neoplastic and nonneoplastic salivary gland disorders in pediatric patients to help clinicians to develop an orderly differential diagnosis that will lead to expedient treatment of pediatric patients with salivary gland lesions. Read More

J Clin Diagn Res 2015 Jun 1;9(6):MD01-3. Epub 2015 Jun 1.

Senior Lecturer, Department of Oral & Maxillofacial Surgery, School of dental Sciences , KIMSDU, Karad, Maharashtra, India .

Ranula is a salivary gland cyst which typically present as localized superficial swelling over the floor of mouth. Complex or plunging ranulas develop when the mucus extravasation extends through or around the mylohyoid muscle, deeper into the neck, and present with neck lump along with or without swelling over floor of mouth. We report a case of large plunging ranula presenting as an isolated large neck mass in a 38-year-old female patient. Read More

Atlas Oral Maxillofac Surg Clin North Am 2015 Mar 9;23(1):49-61. Epub 2015 Jan 9.

Department of Oral and Maxillofacial Surgery, University of Tennessee Medical Center, The University of Tennessee Cancer Institute, 1930 Alcoa Highway, Suite 335, Knoxville, TN 37920, USA. Electronic address:

Laryngoscope 2015 May 28;125(5):1130-6. Epub 2014 Nov 28.

Department of Maxillo-Facial and Oral Surgery, University of Pretoria, South Africa.

Objectives/hypothesis: To describe clinical characteristics of oral mucoceles/ranulas, with a focus on human immunodeficiency virus (HIV)-related salivary gland diseases.

Study Design: A descriptive and clinical study, with review of patient data.

Material And Methods: We reviewed 113 referred cases of oral mucocele. Read More