612 results match your criteria Morganella Infections

Characteristics and Microbiological Profile of Patients with Diabetic Foot Infections in Kuantan, Pahang.

Malays Orthop J 2022 Mar;16(1):11-17

Department of Orthopaedics, Traumatology and Rehabilitation, International Islamic University Malaysia, Kuantan, Malaysia.

Introduction: The number of people suffering from diabetic foot infection (DFI) has increased precipitously over the years in Malaysia, owing to increased population, urbanisation, the surge of number of people with obesity and physical inactivity. As one of the most dreaded complications of diabetes mellitus, DFI is associated with high morbidity and mortality. We aim to study the microbiological profile of patients with DFI at a university hospital in Kuantan, Pahang. Read More

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Morganella morganii, an Emerging Cause of Bloodstream Infections.

Microbiol Spectr 2022 Apr 25:e0056922. Epub 2022 Apr 25.

University of Queenslandgrid.1003.2, Faculty of Medicine, University of Queensland Centre for Clinical Research, Brisbane, Queensland, Australia.

Although recent reports of extensively antibiotic-resistant strains have highlighted the importance of Morganella morganii as an emerging pathogen, the epidemiology of serious infections due to this organism is not well defined. The objective of this study was to determine the incidence, determinants, and outcomes of Morganella morganii bloodstream infections (BSIs). Retrospective, population-based surveillance for Morganella morganii BSIs was conducted in Queensland, Australia, in 2000 to 2019; 709 cases were identified, for an annual incidence of 9. Read More

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Semi-Quantitative Assay to Measure Urease Activity by Urinary Catheter-Associated Uropathogens.

Front Cell Infect Microbiol 2022 22;12:859093. Epub 2022 Mar 22.

Department of Microbiology and Molecular Genetics, McGovern Medical School, The University of Texas Health Science Center, Houston, TX, United States.

Catheter-associated urinary tract infections (CAUTIs) are one of the most common healthcare-associated infections in the US, accounting for over 1 million cases annually and totaling 450 million USD. CAUTIs have high morbidity and mortality rates and can be caused by a wide range of pathogens, making empiric treatment difficult. Furthermore, when urease-producing uropathogens cause symptomatic CAUTI or asymptomatic catheter colonization, the risk of catheter failure due to blockage increases. Read More

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Morganella morganii: An unusual analysis of 11 cases of pediatric urinary tract infections.

J Clin Lab Anal 2022 May 29;36(5):e24399. Epub 2022 Mar 29.

Department of Pediatrics, The First Affiliated Hospital of Xiamen University, Xiamen, China.

Background: The increase in rare opportunistic microbial infections caused by Morganella morganii is alarming across the globe. It has been reported that in cases of urinary tract infections (UTIs) caused by M. morganii, however, few studies investigated children. Read More

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Postvitrectomy endophthalmitis caused by Morganella morganii: a case report and literature review.

BMC Infect Dis 2022 Mar 18;22(1):265. Epub 2022 Mar 18.

Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou Medical Center, No. 5, Fuxing St., Gueishan Dist., Taoyuan City, 333, Taiwan.

Background: Postvitrectomy endophthalmitis is a rare and serious complication following vitreoretinal surgeries. Morganella morganii, an emerging gram-negative, facultative anaerobic rod, is related to severe nosocomial infections in various organs and thus has gained importance in recent decades. Morganella morganii infection following intraocular surgery is rarely reported. Read More

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Microbial Communities in the Extraradicular and Intraradicular Infections Associated With Persistent Apical Periodontitis.

Front Cell Infect Microbiol 2021 12;11:798367. Epub 2022 Jan 12.

The Department of Endodontics, School of Stomatology, Capital Medical University, Beijing, China.

Microorganisms in the complex root canal system and the extraradicular regions, including the periapical lesions and extraradicular biofilm may cause root canal treatment failures. However, few studies described the difference between the intraradicular and extraradicular infections from the same tooth associated with persistent apical periodontitis. This study aimed to characterize the microbiome present in the root canal, extraradicular biofilm, and periapical lesions associated with persistent apical periodontitis. Read More

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Alkaline Urine in the Emergency Department Predicts Nitrofurantoin Resistance.

J Emerg Med 2022 03 6;62(3):368-377. Epub 2022 Jan 6.

Department of Urology, Mayo Clinic, Jacksonville, Florida.

Background: The Proteeae group (i.e., Proteus species, Morganella morganii, and Providencia species) frequently causes urinary tract infections (UTIs) and is generally resistant to nitrofurantoin. Read More

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Development of a Molecular Serotyping Scheme for .

Front Microbiol 2021 23;12:791165. Epub 2021 Nov 23.

Tianjin Union Medical Center, TEDA Institute of Biological Sciences and Biotechnology, The Institute of Translational Medicine Research, Nankai University, Tianjin, China.

, which is often regarded as a human commensal organism, can be an opportunistic pathogen, causing a variety of clinical infections with serious morbidity and mortality. An efficient and convenient method for subtyping and identifying strains in epidemiological surveillance and control is urgently needed. Serotyping based on bacterial surface polysaccharide antigens (O-antigen or K-antigens) is a standard subtyping method for many gram-negative bacteria. Read More

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November 2021

A case of acute encephalopathy associated with acute focal bacterial nephritis.

J Nippon Med Sch 2021 Nov 26. Epub 2021 Nov 26.

Division of Pediatrics, Kawasaki Municipal Tama Hospital.

Acute encephalopathy is a syndrome characterized by an acute onset of disturbance of consciousness. Many acute encephalopathies are caused by viral infections; however, they can also be a result of bacterial infections. Acute focal bacterial nephritis (AFBN) can cause neurological symptoms, such as irritation, unconsciousness, and seizures. Read More

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November 2021

Molecular Analysis of -Harboring Plasmids: Tn Interplasmid Transposition and Tn-Carrying ColRNAI Plasmid Mobilization from Klebsiella pneumoniae to Citrobacter europaeus and Morganella morganii in a Single Patient.

mSphere 2021 12 3;6(6):e0085021. Epub 2021 Nov 3.

Department of Microbiology and Infectious Diseases, Toho University Graduate School of Medicine, Tokyo, Japan.

The spread of Klebsiella pneumoniae carbapenemase (KPC)-producing is a public health concern. KPC-encoding is predominantly spread by strains of a particular phylogenetic lineage, clonal group 258, but can also be spread by horizontal transfer of -carrying plasmids. Here, we report the transfer of a -harboring plasmid via mobilization from K. Read More

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December 2021

The Effects of Chinese Medicine QRD, Antibiotics, and Probiotics on Therapy and Gut Microbiota in Septic Rats.

Front Cell Infect Microbiol 2021 14;11:712028. Epub 2021 Oct 14.

Institute of Acute Abdominal Diseases, Tianjin Hospital of Integrated Chinese and Western Medicine, Tianjin, China.

Sepsis is a common and often treacherous medical emergency with a high mortality and long-term complications in survivors. Though antibiotic therapy can reduce death rate of sepsis significantly, it impairs gut microbiota (GM), which play imperative roles in human health. In this study, we compared the therapeutic effects of antibiotics, probiotics, and Chinese medicine QRD on the survival rates of septic model and observed the GM characteristics of experimental rats 16S rRNA gene amplicon sequencing. Read More

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November 2021

Interplay between Phenotypic Resistance to Relevant Antibiotics in Gram-Negative Urinary Pathogens: A Data-Driven Analysis of 10 Years' Worth of Antibiogram Data.

Life (Basel) 2021 Oct 8;11(10). Epub 2021 Oct 8.

Department of Medical Microbiology, Albert Szent-Györgyi Health Center, Faculty of Medicine, University of Szeged, Semmelweis utca 6., 6725 Szeged, Hungary.

The global emergence of antimicrobial resistance (AMR) has become a critical issue for clinicians, as it puts the decades of developments in the medical field in jeopardy, by severely limiting the useful therapeutic arsenal of drugs, both in nosocomial and community-acquired infections. In the present study, a secondary analysis of taxonomic and resistance data was performed, corresponding to urinary tract infections (UTIs) caused by Gram-negative bacteria, detected between 1 January 2008 to 31 December 2017 at the Albert Szent-Györgyi Health Center, University of Szeged. The following were identifiable from the data collected: year of isolation; outpatient (OP)/inpatient (IP) origin of the isolate; taxonomy; and susceptibility/resistance to selected indicator antibiotics. Read More

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October 2021

Towards A Novel Multi-Epitopes Chimeric Vaccine for Simulating Strong Immune Responses and Protection against .

Int J Environ Res Public Health 2021 10 19;18(20). Epub 2021 Oct 19.

Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah 51452, Saudi Arabia.

is one of the main etiological agents of hospital-acquired infections and no licensed vaccine is available against the pathogen. Herein, we designed a multi-epitope-based vaccine against . Predicted proteins from fully sequenced genomes of the pathogen were subjected to a core sequences analysis, followed by the prioritization of non-redundant, host non-homologous and extracellular, outer membrane and periplasmic membrane virulent proteins as vaccine targets. Read More

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October 2021

Antimicrobial Resistance Patterns in Diabetic Foot Infections, an Epidemiological Study in Northeastern Italy.

Antibiotics (Basel) 2021 Oct 13;10(10). Epub 2021 Oct 13.

U.O. Piede Diabetico, Policlinico Abano Terme, 35031 Padova, Italy.

This study is a retrospective epidemiological assessment of bacterial species isolated from a cohort of out-patients with diabetic foot infections referred to our "Diabetic Foot Unit" over one year, with particular attention to index pathogens, as identified by the EARS Network. and accounted for 33.5% and 11. Read More

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October 2021

Effectiveness of broad-spectrum antiseptics in production of disinfected maggots of Lucilia sericata for use in wound debridement therapy.

Meriem Taleb

Wound Repair Regen 2021 11 11;29(6):1017-1023. Epub 2021 Oct 11.

Department of Biology, Faculty of Nature and Life Sciences, University of Blida 1, Blida, Algeria.

The establishment of low-cost, effective, safe and practical methods is necessary to increase the use of larval therapy in wound care. Although studies on external disinfection of calliphorid eggs have been reported, many studies lack data on the effect of disinfection on egg viability and the microorganisms found before disinfection. Therefore, the main objective of this study was to compare three antiseptic solutions, that is, chlorhexidine (5%), Dakin's solution (0. Read More

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November 2021

Urinary Tract Infections in Elderly Patients: A 10-Year Study on Their Epidemiology and Antibiotic Resistance Based on the WHO Access, Watch, Reserve (AWaRe) Classification.

Antibiotics (Basel) 2021 Sep 11;10(9). Epub 2021 Sep 11.

Department of Medical Microbiology, Albert Szent-Györgyi Health Center, Faculty of Medicine, University of Szeged, 6725 Szeged, Hungary.

The ageing of the population-especially in developed countries-has brought on many societal challenges and has significantly contributed to the burden on healthcare infrastructures worldwide. Elderly persons (aged ≥ 65 years) are at higher risk for developing UTIs, due to a range of intrinsic and extrinsic risk factors, and they often delay seeking treatment. A retrospective observational study was performed regarding the epidemiology and resistance of UTIs in elderly patients. Read More

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September 2021

Pressure ulcers microbiota dynamics and wound evolution.

Sci Rep 2021 09 16;11(1):18506. Epub 2021 Sep 16.

Centre Mutualiste Neurologique Propara, 34090, Montpellier, France.

Bacterial species and their role in delaying the healing of pressure ulcers (PU) in spinal cord injury (SCI) patients have not been well described. This pilot study aimed to characterise the evolution of the cutaneous microbiota of PU in SCI cohort. Twenty-four patients with SCI from a French neurological rehabilitation centre were prospectively included. Read More

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September 2021

Culturomics Approach to Identify Diabetic Foot Infection Bacteria.

Int J Mol Sci 2021 Sep 3;22(17). Epub 2021 Sep 3.

Centre for Modern Interdisciplinary Technologies, Nicolaus Copernicus University in Toruń, Wileńska 4 Str., 87-100 Toruń, Poland.

The main goal of the study was to evaluate the usefulness of the culturomics approach in the reflection of diabetic foot infections (DFIs) microbial compositions in Poland. Superficial swab samples of 16 diabetic foot infection patients (Provincial Polyclinical Hospital in Toruń, Poland) were subjected to culturing using 10 different types of media followed by the identification via the matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) and Biotyper platform. Identified 204 bacterial isolates representing 18 different species-mostly (63%) and (44%). Read More

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September 2021

[Endophthalmitis Caused by Mixed Infections in Silicone Oil-filled Eye:One Case Report].

Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2021 Aug;43(4):659-662

Department of Ophthalmology,Beijing 100730,China.

The incidence of endophthalmitis after vitrectomy is extremely low,especially lower in silicone oil-filled eyes.Silicone oil exerts a toxic effect on the cell membranes of microorganisms and leads to the lack of nutrients.It is thus believed to inhibit the growth of bacteria and fungi. Read More

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Multiresistant zoonotic pathogens isolated from goat milk in Northeastern Brazil.

Comp Immunol Microbiol Infect Dis 2021 Dec 25;79:101701. Epub 2021 Aug 25.

Federal Rural University of Pernambuco - UFRPE, Department of Veterinary Medicine - R. Manuel de Medeiros, s/n - Dois Irmãos, CEP. 52171-900, Recife, PE, Brazil.

Dairy goats play a significant role in socio-economic, cultural, and nutritional development in many countries. This study aimed to identify multiresistant zoonotic pathogens causing mastitis in goats, in addition to characterizing them for the presence of resistance genes and phenotypic resistance. A total of 714 milk samples from 357 lactating goats in 12 farms in the Northeast region of Brazil were analyzed. Read More

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December 2021

Risk Factors of Death in Bloodstream Infections Caused by AmpC β-Lactamase-Producing in Patients with Neoplasia.

Infect Drug Resist 2021 11;14:3083-3097. Epub 2021 Aug 11.

Faculty of Medicine, Fluminense Federal University, Niterói, RJ, Brazil.

Purpose: The infections caused by ESCPM ( spp., spp., spp. Read More

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Complete genome sequence of an extensively drug resistant (XDR) M. morganii SMM01 isolated from a patient with urinary and fecal incontinence.

BMC Genom Data 2021 08 16;22(1):27. Epub 2021 Aug 16.

Department of Biosciences, AMR Laboratory, Sri Sathya Sai Institute of Higher Learning, Puttaparthi, India.

Objective: M. morganii is a gram-negative, non-lactose fermenting and an opportunistic pathogen frequently associated with nosocomial infections. Although first isolated in 1906 from a pediatric fecal sample, not many M. Read More

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Meropenem Versus Piperacillin-Tazobactam for Definitive Treatment of Bloodstream Infections Caused by AmpC β-Lactamase-Producing spp, , , spp, or : A Pilot Multicenter Randomized Controlled Trial (MERINO-2).

Open Forum Infect Dis 2021 Aug 2;8(8):ofab387. Epub 2021 Aug 2.

University of Queensland, UQ Centre for Clinical Research, Brisbane, Australia.

Background: Carbapenems are recommended treatment for serious infections caused by AmpC-producing gram-negative bacteria but can select for carbapenem resistance. Piperacillin-tazobactam may be a suitable alternative.

Methods: We enrolled adult patients with bloodstream infection due to chromosomal AmpC producers in a multicenter randomized controlled trial. Read More

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Diversity in the swimming motility and flagellar regulon structure of uropathogenic Morganella morganii strains.

Int Microbiol 2022 Jan 7;25(1):111-122. Epub 2021 Aug 7.

Institute of Fundamental Medicine and Biology, Kazan (Volga region) Federal University, Kazan, Russia.

In current times, the opportunistic pathogen Morganella morganii is increasingly becoming a cause of urinary tract infections. The condition has been further complicated by the multiple drug resistance of most isolates. Swimming motility plays an important role in the development of urinary tract infections, allowing bacteria to colonize the upper urinary tract. Read More

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January 2022

Occurrence of Rare Pathogens at the Site of Periprosthetic Hip and Knee Joint Infections: A Retrospective, Single-Center Study.

Antibiotics (Basel) 2021 Jul 20;10(7). Epub 2021 Jul 20.

Institut für Medizinische Mikrobiologie und Hygiene, Universitätsklinikum des Saarlandes, 66421 Homburg/Saar, Germany.

The frequency and clinical relevance of rare pathogens at the site of periprosthetic infections of the hip and knee joint and their antibiotic resistance profiles have not yet been assessed in-depth. We retrospectively analyzed all periprosthetic hip and knee joint infections that occurred between 2016 and 2020 in a single center in southwest Germany. Among 165 infections, 9. Read More

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Plasmid analysis of NDM metallo-β-lactamase-producing Enterobacterales isolated in Vietnam.

PLoS One 2021 28;16(7):e0231119. Epub 2021 Jul 28.

AMR Research Center, National Institute of Infectious Diseases, Tokyo, Japan.

Carbapenem-resistant Enterobacterales (CRE) represent a serious threat to public health due to the lack of treatment and high mortality. The rate of antimicrobial resistance of Enterobacterales isolates to major antimicrobials, including carbapenems, is much higher in Vietnam than in Western countries, but the reasons remain unknown due to the lack of genomic epidemiology research. A previous study suggested that carbapenem resistance genes, such as the carbapenemase gene blaNDM, spread via plasmids among Enterobacterales in Vietnam. Read More

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October 2021

Paraneoplastic pemphigus associated with rapidly progressing endophthalmitis caused by : A case report.

Eur J Ophthalmol 2021 Jul 16:11206721211033465. Epub 2021 Jul 16.

Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

Introduction: The ocular presentation of paraneoplastic pemphigus (PNP) has rarely been reported in the literature. In this report, we describe a 61-year-old male presenting with eruptive skin lesions associated with underlying non-Hodgkin's lymphoma who had rapid progressive corneal perforation with secondary endophthalmitis in the setting of PNP.

Case Description: A 61-year-old male presented to the emergency department complaining of skin eruption mimicking Stevens-Johnson syndrome, which was later found to be related to PNP. Read More

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Early Treatment Outcomes for Bloodstream Infections Caused by Potential AmpC Beta-Lactamase-Producing Enterobacterales with Focus on Piperacillin/Tazobactam: A Retrospective Cohort Study.

Antibiotics (Basel) 2021 Jun 2;10(6). Epub 2021 Jun 2.

Institute of Infectious Diseases and Infection Control, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany.

The Gram-negative bacilli spp., spp., , complex, spp. Read More

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Antimicrobial treatment of Morganella morganii invasive infections: Systematic review.

Indian J Med Microbiol 2021 Oct-Dec;39(4):404-412. Epub 2021 Jun 27.

Faculty of Medical Sciences, Department of Pharmacology and Toxicology, University of Kragujevac, Serbia.

Background: Morganella morganii is a Gram-negative, rod-shaped, facultative anaerobic bacillus divided into two subspecies, morganii and sibonii. Previously classified as Proteus morganii, it belongs to human gut commensal microbiota. Nevertheless, on rare occasions, especially in nosocomial and postoperative environment as well as in patients with the impaired immune system and young children, it may cause potentially fatal systemic infection. Read More

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December 2021

and Coinfection in Cobra-Bite Wounds: A Genomic Analysis.

Life (Basel) 2021 Apr 10;11(4). Epub 2021 Apr 10.

Division of Infectious Diseases, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung 40705, Taiwan.

bites cause severe soft tissue injury and are prone to wound infections. The pathogens of bite-wound infections are highly variable in different geographical regions. Here, we report the first coinfection with and from a bite wound with resistome analysis using whole genome sequencing. Read More

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