19,820 results match your criteria Mononeuritis Multiplex


Differential Diagnosis of Churg-Strauss Syndrome with Tingling Sensation and Weakness of the Lower Extremities.

Anesth Pain Med 2018 Dec 28;8(6):e84179. Epub 2018 Nov 28.

Department of Internal Medicine, Division of Rheumatology, Jeju National University Hospital, Jeju, Korea.

Introduction: Churg-Strauss syndrome (CSS; or eosinophilic granulomatosis with polyangiitis) is an extremely rare autoimmune condition characterized by hypereosinophilia and vasculitis of small or medium-sized blood vessels, occurring in patients with asthma and allergic rhinitis.

Case Presentation: A 47-year-old man (height, 175.8 cm and weight, 74. Read More

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http://dx.doi.org/10.5812/aapm.84179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347737PMC
December 2018
1 Read

Neurologic manifestations associated with cryoglobulinemia: A single center experience.

J Neurol Sci 2019 Jan 25;398:121-127. Epub 2019 Jan 25.

Department of Neurology, Cleveland Clinic Foundation, Cleveland, OH 44195, United States. Electronic address:

Introduction: Limited information is available describing the spectrum of neurological complications of cryoglobulinemia.

Methods: Single center retrospective review of patients with neurologic symptoms and elevated serum cryoglobulins, with their potential association being classified as definite, possible, or unlikely using defined criteria.

Results: Among 492 patients, 131 (87 classified as definite and 44 as possible) had neurologic symptoms associated with cryoglobulinemia. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0022510X193005
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http://dx.doi.org/10.1016/j.jns.2019.01.041DOI Listing
January 2019
3 Reads

Entrapment Neuropathies of the Upper Extremity.

Med Clin North Am 2019 Mar;103(2):357-370

Department of Neurology, Massachusetts General Hospital, 55 Fruit Street, WACC 739B, Boston, MA 02114, USA. Electronic address:

Upper extremity entrapment neuropathies are common and can cause pain, sensory loss, and muscle weakness that lead to functional disability. In this article, the authors review common entrapment neuropathies of the upper extremities, including median neuropathy at the wrist (carpal tunnel syndrome), ulnar neuropathy at the elbow, and radial neuropathy. The authors discuss the pathophysiology of nerve compression and typical etiologies, as well as strategies for differentiating between common mimics such as cervical radiculopathy and for selecting between various treatment modalities. Read More

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http://dx.doi.org/10.1016/j.mcna.2018.10.012DOI Listing
March 2019
1 Read

Clinical, electrophysiological and laboratory parameters, and outcome in patients with biopsy proven systemic and nonsystemic vasculitic neuropathy.

Neurol India 2019 Jan-Feb;67(Supplement):S62-S70

Department of Neurochemistry, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.

Aim: To describe the clinical and laboratory findings of patients with biopsy proven vasculitic neuropathy.

Introduction: Peripheral neuropathies form one of the most common disorders of the nervous system. However, more than 50% of them are labelled as 'idiopathic' and, therefore, treatment options become less. Read More

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http://dx.doi.org/10.4103/0028-3886.250709DOI Listing
January 2019
1 Read

Silent acute myocarditis in eosinophilic granulomatosis with polyangiitis.

Acta Reumatol Port 2018 Oct-Dec;43(4):309-313

São João Hospital Centre.

Eosinophilic granulomatosis with polyangiitis is a rare multisystemic disorder, characterized by necrotizing vasculitis affecting small to medium-sized vessels, associated with asthma and eosinophilia. Cardiac involvement is the most important predictor of mortality and it seems to be more frequent in anti-neutrophil cytoplasmic antibodies-negative patients. Cardiomyopathy and congestive heart failure can occur but a significant proportion of patients are asymptomatic. Read More

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January 2019
2 Reads

Hand tendinopathy risk factors in Taiwan: A population-based cohort study.

Medicine (Baltimore) 2019 Jan;98(1):e13795

Department of Nursing, Chung Hwa University of Medical Technology, Tainan, Taiwan.

De Quervain's disease, carpal tunnel syndrome (CTS), and trigger finger (digit) are three common pathological conditions of the hand. They are considered overuse syndromes and occur predominantly in females. The prevalence rate and cause-specific risks of these three tendinopathies have not yet been clarified. Read More

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http://dx.doi.org/10.1097/MD.0000000000013795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344158PMC
January 2019
1 Read

Carpal tunnel syndrome caused by synovial osteochondromatosis of the finger flexor tendon: A case report.

Medicine (Baltimore) 2018 Dec;97(52):e13943

Department of Rehabilitation Medicine.

Rationale: Carpal tunnel syndrome (CTS) is the most common peripheral nerve neuropathy resulting from compression of the median nerve as it traverses the carpal tunnel. The pathophysiology of this condition is multifactorial, and majority of cases of CTS are idiopathic. We report cases of CTS caused by synovial osteochondromatosis (SOC), which has rarely been reported. Read More

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http://dx.doi.org/10.1097/MD.0000000000013943DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314781PMC
December 2018
1 Read

The cubital tunnel syndrome caused by intraneural ganglion cyst of the ulnar nerve at the elbow: a case report.

BMC Neurol 2018 Dec 22;18(1):217. Epub 2018 Dec 22.

Department of Hand Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University, #79 Qingchun Road, Hangzhou, Zhejiang Province, 310003, People's Republic of China.

Background: Cubital tunnel syndrome is common nerve compression syndrome among peripheral nerve compression diseases. However, the syndrome caused by intraneural ganglion cysts has been rarely reported. Medical approaches, like ultrasound-guided aspiration and open surgical treatment remain to be discussed. Read More

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https://bmcneurol.biomedcentral.com/articles/10.1186/s12883-
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http://dx.doi.org/10.1186/s12883-018-1229-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303969PMC
December 2018
7 Reads

Compressive radial neuropathy by a synovial cyst during pregnancy: A clinical case report.

Medicine (Baltimore) 2018 Dec;97(49):e13455

Department of Physical Medicine and Rehabilitation, Tung's Taichung Metroharbor Hospital, Taichung, Taiwan.

Rationale: Compressive radial neuropathy by a synovial cyst in the radial tunnel during pregnancy is a rare occurrence. The management of radial nerve compression caused by a synovial cyst in a pregnant patient is a surgical dilemma owing to the fetal and maternal risks of treatment.

Patient Concerns And Diagnosis: A 37-year-old pregnant woman presented with progressive forearm pain at the gestational age of 12 weeks. Read More

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http://dx.doi.org/10.1097/MD.0000000000013455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310501PMC
December 2018
7 Reads

[A Case of Sjögren's Syndrome with Multiple Stenoses of the Cerebral Arteries and Transient Neurological Symptoms and Signs].

Brain Nerve 2018 Dec;70(12):1389-1396

Department of Neurology, Japanese Red Cross Yamaguchi Hospital.

A 31-year-old woman was admitted to the hospital after several episodes of transient numbness in her fingers and dysarthria. No neurological symptoms and signs were observed in this patient on admission; however, blood tests revealed elevated amylase and immunoglobulin G levels, an increased erythrocyte sedimentation rate, and positive anti-Sjögren's-syndrome (SjS)-related antigen A antibodies. The cerebrospinal fluid examination revealed a slight increase in the cell count and protein content. Read More

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http://dx.doi.org/10.11477/mf.1416201198DOI Listing
December 2018
6 Reads

The relationship between type 1 IFN and vasculopathy in anti-MDA5 antibody-positive dermatomyositis patients.

Rheumatology (Oxford) 2018 Dec 11. Epub 2018 Dec 11.

Department of Rheumatology, Faculty of Medicine, Saga University, Saga, Japan.

Objectives: Based on the antibody profiles of inflammatory myositis patients, we investigated the type 1 IFN (T1-IFN) signature in serum and DM skin to determine the relationship between T1-IFN and vasculopathy in anti-melanoma differentiation-associated 5 gene (MDA5) antibody-positive DM patients.

Methods: We examined 47 patients with new-onset inflammatory myositis. We divided them into three groups: the anti-MDA5 antibody-positive patients (MDA5 group, n = 16), the anti-aminoacyl-tRNA synthetase antibody-positive patients (aminoacyl-tRNA synthetase group, n = 12), and the double-negative patients (n = 19). Read More

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https://academic.oup.com/rheumatology/advance-article/doi/10
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http://dx.doi.org/10.1093/rheumatology/key386DOI Listing
December 2018
11 Reads

Epidemiology and etiology of secondary piriformis syndrome: A single-institution retrospective study.

J Clin Neurosci 2019 Jan 24;59:209-212. Epub 2018 Oct 24.

Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL, USA. Electronic address:

Piriformis syndrome (PS) is a rare etiology of extra-spinal sciatica in which pathologies associated with or around the piriformis muscle (PM) irritate the adjacent sciatic nerve (SN), however, there is scarcity in the literature regarding its exact etiologies, thus, we performed a retrospective study to elucidate the epidemiology of PS and assess various causes of the syndrome. Our study included patients assessed at our institution who presented with sciatica of non-spinal origin between May 2014 and December 2015. Radiology reports of all patients who received pelvic MRI were examined for positive findings involving PM and SN. Read More

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http://dx.doi.org/10.1016/j.jocn.2018.10.069DOI Listing
January 2019
7 Reads

EMG in piriformis syndrome diagnosis: Reliability of peroneal H-reflex according to results obtained after surgery, Botox injection and medical treatment.

J Clin Neurosci 2019 Jan 28;59:55-61. Epub 2018 Nov 28.

Orthopedic Surgery Department, Sacré-Coeur Hospital, P.O. Box 116, Hazmieh, Lebanon.

Diagnosing piriformis syndrome (PS) throughout the past decades was not that easy, however peroneal H-reflex was proved as reliable test for PS with the change in wave amplitude and delay in conduction as parameters for diagnosis. We interpreted these parameters according to treatment's results carried out for patients presenting clinical PS, aiming to define a threshold value for peroneal H-reflex delay to accurately diagnose. A retrospective mono-centric review of 27 patients, 9 females and 18 males, aged 22-65 years, benefited from peroneal H-reflex test and treated for clinical PS. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09675868183056
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http://dx.doi.org/10.1016/j.jocn.2018.11.007DOI Listing
January 2019
8 Reads

Effects of transcutaneous electrical nerve stimulation in the Management of Post-Injection Sciatic Pain in a non-randomized controlled clinical trial in Nnewi, Nigeria.

BMC Complement Altern Med 2018 Nov 26;18(1):310. Epub 2018 Nov 26.

Department of Medical Rehabilitation, Faculty of Health Sciences and Technology, University of Nigeria|, Enugu Campus, Enugu State, Nigeria.

Background: Many studies on transcutaneous electrical nerve stimulation (TENS) had been undertaken to explore its pain relieving efficiency on several medicals/surgical conditions but none, specifically, had been carried out to determine the effect it has on post-injection sciatic pain (PISP) which comes about from wrong administration of intramuscular pain. This study aims to assess the effects of TENS in the management of PISP.

Methods: A total of 72 PISP subjects comprising 40 test subjects and 32 control subjects participated in a non-randomized controlled clinical trial in the current study. Read More

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http://dx.doi.org/10.1186/s12906-018-2373-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258320PMC
November 2018
1 Read

Which Factors Affect the Rate of Surgery Performed in Patients with Carpal Tunnel Syndrome?

J Hand Surg Asian Pac Vol 2018 Dec;23(4):562-565

‡ Department of Orthopaedic Surgery, Seoul National University Boramae Medical Center, Seoul, Korea.

Background: Carpal tunnel release is recommended when patients have positive electrophysiologic test and their symptoms are not resolved in spite of conservative treatment. However, only some of them eventually undergo the surgery. The purposes of this study, therefore, were to evaluate the rate of carpal tunnel release performed among the patients with positive electrophysiologic test, and to identify which factors were associated with the rate of the surgery. Read More

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http://dx.doi.org/10.1142/S2424835518500583DOI Listing
December 2018
7 Reads

Carpal Tunnel Syndrome and Flexor Tendon Rupture in the Wrist with Asymptomatic Scapholunate Advanced Collapse: A Case Report.

J Hand Surg Asian Pac Vol 2018 Dec;23(4):589-592

1 Department of Orthopedic Surgery, Hokkaido Saiseikai Otaru Hospital, Otaru, Japan.

We experienced a rare case of carpal tunnel syndrome and rupture of the flexor digitorum profundus tendon to the index finger with a scapholunate advanced collapse wrist. We speculated that the lunate that had extruded into the carpal tunnel compressed the median nerve and caused wear of the flexor tendon following neglected perilunate subluxation. Carpal tunnel release, opponensplasty by palmaris longus tendon transfer, and a bridge graft by a half-slip of the flexor carpi radialis tendon resulted in recovery of pinch function and improvement in numbness of the hand. Read More

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http://dx.doi.org/10.1142/S2424835518720360DOI Listing
December 2018
2 Reads

Effects of Anthropometric Measurements on Treatment Outcomes in Patients with Carpal Tunnel Syndrome.

J Hand Surg Asian Pac Vol 2018 Dec;23(4):528-532

* Department of Physical Medicine and Rehabilitation, Uludag University School of Medicine, Bursa, Turkey.

Background: The purpose of this study was to investigate the relationship between anthropometric hand/wrist measurements and outcomes following static wrist splintage in patients with mild-to-moderate carpal tunnel syndrome (CTS).

Methods: Thirty nine patients with mild-to-moderate CTS were enrolled in this study. Anthropometric measurements of hand and wrist including wrist width, wrist depth, palm length, hand length, wrist ratio (wrist depth/wrist width) and wrist/palm ratio (wrist depth/palm length) were recorded as well as body mass index and ultrasonographic cross sectional area of median nerve. Read More

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http://dx.doi.org/10.1142/S2424835518500534DOI Listing
December 2018
8 Reads

Persisting Complaints after Carpal Tunnel Release: Nerve Compression by the Palmaris Profundus Muscle.

J Hand Surg Asian Pac Vol 2018 Dec;23(4):593-595

† OLV van Lourdes Hospital, Waregem, Belgium.

We present the case of a 66-year-old man who had persisting complaints after initial classical open carpal tunnel release. During revision a reversed palmaris profundus muscle was identified as being the cause of residual compression of the median nerve. Neurolysis with release of the palmaris profundus muscle was performed without resection of this anatomical variant and resulted in full resolution of the complaints. Read More

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http://dx.doi.org/10.1142/S2424835518720372DOI Listing
December 2018
1 Read

Mononeuritis multiplex: an uncommon neurological manifestation of cytomegalovirus reactivation in an HIV-infected patient.

BMC Infect Dis 2018 Nov 12;18(1):554. Epub 2018 Nov 12.

Infectious Diseases Department, Centro Hospitalar de São João, Alameda Professor Hernâni Monteiro, 4200-319, Porto, Portugal.

Background: Cytomegalovirus (CMV) reactivation with neurological involvement in patients with acquired immunodeficiency syndrome (AIDS) is increasingly rare since the introduction of antiretroviral therapy (ART). Manifestations include encephalitis, myelitis, polyradiculopathy and, less commonly, mononeuritis multiplex (MNM). We report a case of disseminated CMV disease with gastrointestinal and peripheral and central nervous system involvement in a patient with AIDS, manifesting primarily as MNM. Read More

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https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128
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http://dx.doi.org/10.1186/s12879-018-3501-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233374PMC
November 2018
10 Reads

Report of an Isolated L5 Radiculopathy Caused by an L2-3 Disc Herniation and Review of the Literature.

Cureus 2018 Apr 30;10(4):e2552. Epub 2018 Apr 30.

Neurological Surgery, UC Health, Cincinatti, USA.

Intervertebral disc herniation is a common cause of radiculopathy. Disc herniations occurring in the lumbar spine typically affect the nerve root exiting under the pedicle of the vertebral body, one level caudal. However, in rare cases, a disc herniation can cause remote isolated radicular symptoms. Read More

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https://www.cureus.com/articles/12201-report-of-an-isolated-
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http://dx.doi.org/10.7759/cureus.2552DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218189PMC
April 2018
10 Reads

The effectiveness of ultrasonography and ultrasonographic elastography in the diagnosis of carpal tunnel syndrome and evaluation of treatment response after steroid injection.

Eur J Radiol 2018 Nov 24;108:172-176. Epub 2018 Sep 24.

Marmara University, Faculty of Medicine, Department of Radiology, Istanbul, Turkey. Electronic address:

Purpose: To evaluate if there is a place for ultrasonography (US) and ultrasonographic elastography (UE) in the diagnosis and follow up of carpal tunnel syndrome treatment.

Materials And Methods: The study was performed on 25 patients (study group) and 17 healthy volunteers (control group). Measured US and UE criteria were median nerve area (MNA), proximal median nerve area (pMNA), difference between MNA and pMNA (dMNA) and strain values of carpal tunnel content (CTC) and median nerve (MN). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0720048X183034
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http://dx.doi.org/10.1016/j.ejrad.2018.09.027DOI Listing
November 2018
8 Reads

Elbow Surgery in Athletes.

Sports Med Arthrosc Rev 2018 Dec;26(4):181-184

Andrews Sports Medicine, Birmingham, AL.

Injuries and disorders of the elbow in athletes are common especially among throwing athletes. Common injuries encountered in the throwing athlete include ulnar collateral ligament injuries, ulnar neuritis, capitellar osteochondritis dissecans, valgus extension overload with posterior olecranon impingement, olecranon stress fracture, and loose bodies. A thorough knowledge of both the functional anatomy as well as throwing biomechanics are required to properly diagnosis and treat these problems. Read More

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http://dx.doi.org/10.1097/JSA.0000000000000227DOI Listing
December 2018
2 Reads

Predictive factors of the neuropathic pain in patients with carpal tunnel syndrome and its impact on patient activity.

Pain Manag 2018 Nov 5;8(6):455-463. Epub 2018 Nov 5.

CS General Ricardos. Madrid 28019, Spain.

Aim: To determine the predictive factors of the neuropathic pain in patients with carpal tunnel syndrome (CTS), and the impact of such neuropathic pain on patient's activity.

Methods: Douleur Neuropathique 4 questionnaire, Short Form-Brief Pain Inventory test and Boston Carpal Tunnel Syndrome Questionnaire were completed and results were stratified according neuropathic pain and work activity of the patients.

Results: 69 of 90 patients with CTS had neuropathic pain (76. Read More

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http://dx.doi.org/10.2217/pmt-2018-0045DOI Listing
November 2018
3 Reads

Ultrasonographic and clinical evaluation of additional contribution of kinesiotaping to tendon and nerve gliding exercises in the treatment of carpal tunnel syndrome

Turk J Med Sci 2018 Oct 31;48(5):925-932. Epub 2018 Oct 31.

Background and aim: This study aims to ultrasonographically and clinically evaluate the additive contribution of kinesiotaping to tendon and nerve gliding exercises in the treatment of mild or moderate carpal tunnel syndrome (CTS). Materials and methods: Thirty-eight wrists of patients (n = 21) with CTS were randomized into two groups as the intervention group (n = 19) and the control group (n = 19). Tendon and nerve gliding exercises were given to both groups. Read More

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http://dx.doi.org/10.3906/sag-1709-72DOI Listing
October 2018
13 Reads

Peroneal nerve mononeuropathy associated with herpes zoster. A case report.

Neurol Sci 2018 Oct 31. Epub 2018 Oct 31.

Neuromuscular Unit, Hospital Universitario del Sureste, Ronda del Sur 10, E28500, Arganda del Rey (Madrid), Spain.

Background: Sensory or motor syndromes, especially mononeuropathies, are infrequent complications of herpes zoster.

Case Report: We describe a 77-year-old woman who developed a severe right common peroneal nerve mononeuropathy with clinical onset 10 days after a vesicular rash consistent with herpes zoster in the territory of distribution of this nerve.

Conclusion: To our knowledge, peroneal nerve mononeuropathy associated with herpes zoster has not been reported previously. Read More

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http://link.springer.com/10.1007/s10072-018-3621-x
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http://dx.doi.org/10.1007/s10072-018-3621-xDOI Listing
October 2018
5 Reads

Ultrasound-guided decompression surgery of the tarsal tunnel: a novel technique for the proximal tarsal tunnel syndrome-Part II.

Surg Radiol Anat 2019 Jan 31;41(1):43-51. Epub 2018 Oct 31.

Department of Anatomy, Histology and Embryology, Division of Clinical and Functional Anatomy, Medical University of Innsbruck (MUI), Müllerstr. 59, 6020, Innsbruck, Austria.

Background: The aim of this study is to provide a safe ultrasound-guided minimally invasive surgical approach for a proximal tarsal tunnel release concerning nerve entrapments.

Methods And Results: The study was carried out on ten fresh-frozen feet. All of them were examined by high resolution ultrasound at the medial ankle region. Read More

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http://link.springer.com/10.1007/s00276-018-2127-9
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http://dx.doi.org/10.1007/s00276-018-2127-9DOI Listing
January 2019
15 Reads

Does median nerve translate pre- and postoperatively in carpal tunnel syndrome?

Eklem Hastalik Cerrahisi 2018 Dec;29(3):165-9

Department of Orthopedics and Traumatology, Selçuk University Medical Faculty, 42130 Selçuklu, Konya, Turkey.

Objectives: This study aims to evaluate the distance between the median nerve and the hook of the hamate pre- and postoperatively in patients with carpal tunnel syndrome and to investigate the efficiency of magnetic resonance imaging in diagnosis and postoperative follow-up.

Patients And Methods: Median nerve decompression was performed by releasing the carpal tunnel in 15 patients (4 males, 11 females; mean age 51 years; range, 41 to 66 years) with carpal tunnel syndrome. The shortest distance between the median nerve and the hook of the hamate was measured with magnetic resonance imaging preoperatively and at three months after the operation and radial and ulnar translations were assessed. Read More

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http://dx.doi.org/10.5606/ehc.2018.61262DOI Listing
December 2018
2 Reads

Clinical-anatomic mapping of the tarsal tunnel with regard to Baxter's neuropathy in recalcitrant heel pain syndrome: part I.

Surg Radiol Anat 2019 Jan 27;41(1):29-41. Epub 2018 Oct 27.

Department of Anatomy, Histology and Embryology, Division of Clinical and Functional Anatomy, Medical University of Innsbruck, Müllerstr. 59, 6020, Innsbruck, Austria.

Purpose: Neuropathy of the Baxter nerve (BN) seems to be the first cause of the heel pain syndrome (HPS) of neurological origin.

Methods: 41 alcohol-glycerol embalmed feet were dissected. We documented the pattern of the branches of the tibial nerve (TN) and describe all relevant osteofibrous structures. Read More

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http://dx.doi.org/10.1007/s00276-018-2124-zDOI Listing
January 2019
10 Reads

Neuroborreliosis.

Authors:
John J Halperin

Neurol Clin 2018 Nov;36(4):821-830

Department of Neurosciences, Overlook Medical Center, 99 Beauvoir Avenue, Summit, NJ 07902, USA; Sidney Kimmel Medical College, Thomas Jefferson University, 1025 Walnut Street, Philadelphia, PA 19107, USA. Electronic address:

Neurologic manifestations of nervous system infection with Borrelia burgdorferi, Borrelia garinii, and Borrelia afzelii are qualitatively similar, and include lymphocytic meningitis, cranial neuritis, radiculoneuritis, and other focal or multifocal mononeuropathies. Parenchymal central nervous system (CNS) infection occurs rarely. Neurobehavioral changes are common, but are rarely evidence of CNS infection. Read More

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http://dx.doi.org/10.1016/j.ncl.2018.06.006DOI Listing
November 2018
3 Reads

The diagnostic accuracy of median nerve ultrasonography in elderly patients with carpal tunnel syndrome: sensitivity and specificity assessment.

Clin Interv Aging 2018 11;13:1953-1962. Epub 2018 Oct 11.

Department of Neurobiology, Care Sciences and Society, Karolinska Institute, Stockholm, Sweden,

Background: Accurate diagnosis of carpal tunnel syndrome (CTS), the most common entrapment neuropathy, and its differentiation from other diseases are essential, especially in older individuals with advanced symptoms and modified electrophysiological abnormalities. The current study was conducted to evaluate the diagnostic accuracy of ultrasonography (US), regarding sensitivity and specificity in the diagnosis of CTS in elderly patients.

Methods: Individuals with upper limb complaints and reference subjects were recruited from the Rofaydeh Hospital, Tehran, Iran, from June 2013 to October 2014 - (15 months). Read More

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https://www.dovepress.com/the-diagnostic-accuracy-of-median-
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http://dx.doi.org/10.2147/CIA.S177307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187921PMC
December 2018
12 Reads

The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial.

Lancet 2018 10;392(10156):1423-1433

Arthritis Research UK Primary Care Centre, Research Institute for Primary Care and Health Sciences, Keele University, Keele, UK; Haywood Academic Rheumatology Centre, Haywood Hospital, Staffordshire and Stoke-on-Trent Partnership NHS Trust, Stoke-on-Trent, UK. Electronic address:

Background: To our knowledge, the comparative effectiveness of commonly used conservative treatments for carpal tunnel syndrome has not been evaluated previously in primary care. We aimed to compare the clinical and cost-effectiveness of night splints with a corticosteroid injection with regards to reducing symptoms and improving hand function in patients with mild or moderate carpal tunnel syndrome.

Methods: We did this randomised, open-label, pragmatic trial in adults (≥18 years) with mild or moderate carpal tunnel syndrome recruited from 25 primary and community musculoskeletal clinics and services. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01406736183157
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http://dx.doi.org/10.1016/S0140-6736(18)31572-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196880PMC
October 2018
15 Reads

Steroid injection or wrist splint for first-time carpal tunnel syndrome?

Authors:
Isam Atroshi

Lancet 2018 10;392(10156):1383-1384

Department of Clinical Sciences and Department of Orthopaedics, Lund University, Lund, Sweden; Department of Orthopaedics, Hässleholm-Kristianstad, Hässleholm SE 28125, Sweden. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(18)31929-9DOI Listing
October 2018
2 Reads

An Unusual Presentation of Chronic Subdural Hematoma with Isolated Footdrop.

World Neurosurg 2019 Jan 13;121:166-168. Epub 2018 Oct 13.

Division of Neurosurgery, Maimonides Medical Center, Brooklyn, New York, USA; Department of Neurosurgery, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, USA. Electronic address:

Background: Patients with chronic subdural hematoma (CSDH) typically present with symptoms of increased intracranial pressure, including headache, nausea/vomiting, and somnolence, or with contralateral weakness. Compression of the convexity cerebral cortex usually causes motor deficit that is more readily appreciated in the upper extremity rather than in the leg, and very subtle deficit may be detected only by looking for pronator drift. The precise pattern of signs and symptoms in CSDH may vary from case to case depending on the specific anatomy of compression, but isolated lower extremity weakness is rare. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183233
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http://dx.doi.org/10.1016/j.wneu.2018.10.042DOI Listing
January 2019
11 Reads

Subcutaneous Ulnar Nerve Transposition Using Osborne's Ligament as a Ligamentodermal or Ligamentofascial Sling.

Am J Orthop (Belle Mead NJ) 2018 Sep;47(9)

Department of Orthopaedic Surgery and Sports Medicine, University of Kentucky, Lexington, KY.

The ulnar nerve is most commonly compressed at the elbow in the cubital tunnel. Conservative and operative treatments have been applied for cubital tunnel syndrome. Surgical management options include decompression, medial epicondylectomy, and various anterior transposition techniques. Read More

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http://dx.doi.org/10.12788/ajo.2018.0070DOI Listing
September 2018
17 Reads

Guiding Treatment for Carpal Tunnel Syndrome.

Authors:
Leilei Wang

Phys Med Rehabil Clin N Am 2018 11 17;29(4):751-760. Epub 2018 Sep 17.

Department of Rehabilitation Medicine, School of Medicine, University of Washington, 1959 Northeast Pacific Street, Box 356157, Seattle, WA 98195, USA. Electronic address:

Making the correct carpal tunnel syndrome diagnosis is the most important step in treatment. Electrodiagnosis can confirm carpal tunnel syndrome and eliminate mimicking diseases from the differential. Treatment should provide satisfactory pain relief and protection of the median nerve from further deterioration. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10479651183079
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http://dx.doi.org/10.1016/j.pmr.2018.06.009DOI Listing
November 2018
2 Reads

Rates of Carpal Tunnel Syndrome in a State Workers' Compensation Information System, by Industry and Occupation - California, 2007-2014.

MMWR Morb Mortal Wkly Rep 2018 Oct 5;67(39):1094-1097. Epub 2018 Oct 5.

Carpal tunnel syndrome (CTS) occurs when the median nerve becomes compressed as it passes through the wrist within the carpal tunnel, resulting in pain, tingling, weakness, or numbness in the hand or the wrist. Occupational risk factors for CTS include engaging in work activities that require forceful, repetitive tasks, prolonged use of the hands or wrists in an awkward posture, or vibration (1). To assess trends and identify high-risk industries and occupations for CTS, the California Department of Public Health (CDPH) analyzed California workers' compensation claims for CTS by industry (2007-2014) and occupation (2014) and calculated rates per full-time equivalent (FTE) worker. Read More

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http://dx.doi.org/10.15585/mmwr.mm6739a4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171895PMC
October 2018
3 Reads

Fixed Anterior Position of Ulnar Nerve around Medial Condyle of Elbow with Bony Mass Causing Cubital Tunnel Syndrome.

J Hand Surg Asian Pac Vol 2018 Sep;23(3):399-403

‡ Department of Radiology, Seoul National University College of Medicine, Seoul, Korea.

A 20-year-old male has presented with mild numbness and tingling sensation at 4, 5 finger of his left hand. Simple radiograph and MRI images revealed bony mass at medial joint space of ulno-humeral joint. After surgical exploration, we found that there were two cause of ulnar nerve irritation symptom. Read More

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http://dx.doi.org/10.1142/S2424835518720232DOI Listing
September 2018
5 Reads

The Austrian Flag - Severe Carpal Tunnel Syndrome: A Case Report.

J Hand Surg Asian Pac Vol 2018 Sep;23(3):412-414

* Department of Hand Surgery & Peripheral Nerve Surgery, Royal North Shore Hospital, St. Leonards, The Children's Hospital at Westmead, University of Sydney, Sydney, Australia.

In severe carpal tunnel syndrome a continuum of neural changes takes place depending on the degree and duration of the compression, beginning with breakdown of the blood-nerve barrier, followed by endoneurial oedema and, subsequently, perineurial thickening and ischemia. Persisting chronic compression will eventually result in axonal degeneration. We report a case of longstanding carpal tunnel syndrome with amyloid deposits and the unusual intraoperative 'Austrian flag' sign. Read More

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https://www.worldscientific.com/doi/abs/10.1142/S24248355187
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http://dx.doi.org/10.1142/S2424835518720268DOI Listing
September 2018
3 Reads

Wallis Interspinous Spacer for Treatment of Primary Lumbar Disc Herniation: Three-Year Results of a Randomized Controlled Trial.

World Neurosurg 2018 Dec 24;120:e1331-e1336. Epub 2018 Sep 24.

Southern Medical University, Guangzhou, People's Republic of China; Department of Orthopedics, The Third Affiliated Hospital of Southern Medical University, Guangzhou, People's Republic of China. Electronic address:

Background: Limited data have been reported showing whether the second-generation Wallis interspinous spacer improves function after lumbar spine decompression or discectomy.

Methods: We evaluated Wallis interspinous spacer placement in patients with low back pain or sciatica secondary to a confirmed diagnosis of primary lumbar disc herniation. The patients were treated from July 2008 to July 2011 at 1 institution. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.09.086DOI Listing
December 2018
8 Reads

Why do we know so little about return to work after carpal tunnel release?

Scand J Work Environ Health 2018 11 27;44(6):555-556. Epub 2018 Sep 27.

Finnish Institute of Occupational Health, Helsinki, Finland.

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http://dx.doi.org/10.5271/sjweh.3771DOI Listing
November 2018

[Tear of the Distal Biceps Brachii Tendon - Correlation of Ultrasound and Operative Findings, Surgical Therapy Results].

Acta Chir Orthop Traumatol Cech 2018 ;85(3):199-203

Ortopedická klinika Lékařské fakulty Univerzity Karlovy a Fakultní nemocnice Hradec Králové.

PURPOSE OF THE STUDY When treating tears of the distal biceps brachii muscle tendon, we repeatedly noticed a difference between the preoperative ultrasound findings and the operative findings. The aim of the study was to retrospectively correlate these findings in order to determine the sensitivity of the ultrasound examination in everyday orthopaedic practice. Moreover, we compared the results and complications of surgical treatment through two operative techniques used at our department. Read More

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January 2019
9 Reads

Transient femoral nerve palsy in spica cast treatment for developmental dysplasia of the hip.

Pediatr Med Chir 2018 Sep 26;40(2). Epub 2018 Sep 26.

Clinical Surgical Department, Diagnostic and Pediatric Sciences, Locomotor System Diseases Unit, University of Pavia, Pavia.

A 4 months and half female child come to our attention for congenital dislocation of the left hip, previously treated in another hospital with abduction bracing, without satisfactory results. After progressive longitudinal bilateral traction, closed reduction under general anesthesia was performed and a spica cast was applied in the so-called human position. The patients remained in the spica cast for 6 weeks and then the plaster cast was renewed in narcosis for another 6 weeks. Read More

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http://dx.doi.org/10.4081/pmc.2018.200DOI Listing
September 2018
2 Reads

Needle EMG of Thenar Muscles in Less Severe Carpal Tunnel Syndrome.

J Clin Neurophysiol 2018 Nov;35(6):481-484

Department of Neurology, Mayo Clinic, Jacksonville, Florida, U.S.A.

Introduction: The value of needle electromyography (EMG) in thenar muscles in patients with less severe carpal tunnel syndrome is controversial.

Methods: Patients referred for electrodiagnostic testing for carpal tunnel syndrome, in which nerve conduction study demonstrated median sensory nerve conduction study abnormalities and either normal median motor nerve conduction study or only prolonged median motor distal latencies (DLs) (with normal amplitudes) were prospectively studied. Patients with low-median compound muscle action potential amplitudes or any other EMG abnormality were excluded. Read More

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http://Insights.ovid.com/crossref?an=00004691-900000000-9952
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http://dx.doi.org/10.1097/WNP.0000000000000519DOI Listing
November 2018
3 Reads

Evaluation of dexamethasone treated mesenchymal stem cells for recovery in neurotmesis model of peripheral nerve injury.

Neurol Res 2018 Dec 22;40(12):1060-1070. Epub 2018 Sep 22.

e Department of Physical Medicine, and Rehabilitation , Iran University of Medical Sciences , Tehran , Iran.

Objective: Peripheral nerve injuries comprise significant portion of the nervous system injuries. Although peripheral nerves show some capacity of regeneration after injury, the extent of regeneration is not remarkable. The present study aimes to evaluate the regeneration of transected sciatic nerve by a therapeutic value of dexamethasone (DEX) associated with cell therapy (Cell) and biodegradable membrane (Mem) in rat. Read More

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http://dx.doi.org/10.1080/01616412.2018.1517859DOI Listing
December 2018
1 Read

Triamcinolone Acetonide affects TGF-β signaling regulation of fibrosis in idiopathic carpal tunnel syndrome.

BMC Musculoskelet Disord 2018 Sep 22;19(1):342. Epub 2018 Sep 22.

Biomechanics & Tendon and Soft Tissue Biology Laboratory, Division of Orthopedic Research, Rochester, USA.

Background: Fibroblast behavior and cell-matrix interactions of cells from normal and idiopathic carpal tunnel syndrome (CTS) subsynovial connective tissue (SSCT) with and without Triamcinolone Acetonide (TA) were compared in this study. A cell-seeded gel contraction model was applied to investigate the effect of steroid treatment on SSCT fibroblast gene expression and function.

Methods: SSCT cells were obtained from CTS patients and fresh cadavers. Read More

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http://dx.doi.org/10.1186/s12891-018-2260-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151186PMC
September 2018
9 Reads
1.900 Impact Factor

Unusual variant of distal biceps femoris muscle associated with common peroneal entrapment neuropathy: A cadaveric case report.

Medicine (Baltimore) 2018 Sep;97(38):e12274

Department of Anatomy and Cell Biology, Graduate School of Medicine, Kangwon National University, Kangwon.

Rationale: The anatomical variant of the distal biceps femoris muscle with regard to common peroneal nerve entrapment neuropathy (CPNe) was suggested through magnetic resonance images (MRI) study.

Patient Concerns: An unusual variant of distal biceps femoris muscle was observed in 78 years old male cadaver.

Diagnoses: The short head of biceps femoris muscle (SHBFM) was extended more distal and posteriorly. Read More

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http://dx.doi.org/10.1097/MD.0000000000012274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160238PMC
September 2018
2 Reads

Analysis of the muscle tissue of Wistar rats submitted to the sciatic nerve compression model and cryotherapy.

Einstein (Sao Paulo) 2018 Sep 17;16(3):eAO4206. Epub 2018 Sep 17.

Universidade Estadual do Oeste do Paraná, Cascavel, PR, Brazil.

Objective: To evaluate the effects of right sciatic nerve compression and cryotherapy on muscle tissue.

Methods: We used 42 male Wistar rats, subdivided in the following Groups Control, Injury 3, Injury 8 and Injury 15 submitted to nerve compression and euthanized in the 3rd, 8th and 15th day after surgery. The Cryotherapy Injury 3 was entailed treatment with cryotherapy by immersion of the animal in recipient for 20 minutes during 1 day, then animals were euthanized at the 3rd day after surgery, and the Cryotherapy Injury 8 and the Cryotherapy Injury 15 was treated for 6 days, and euthanized at the 8th and 15th day after surgery. Read More

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http://dx.doi.org/10.1590/S1679-45082018AO4206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178854PMC
September 2018
3 Reads

Cost, Value, and Patient Satisfaction in Carpal Tunnel Surgery.

Orthop Clin North Am 2018 Oct 16;49(4):503-507. Epub 2018 Aug 16.

Campbell Clinic-University of Tennessee, Department of Orthopaedic Surgery and Biomedical Engineering, 1211 Union Avenue, Suite 510, Memphis, TN 38104, USA.

The cost of carpal tunnel release (CTR) surgery can be decreased and patient satisfaction increased by a few relatively simple changes. Although cost estimates vary in the literature, most investigators agree that open CTR costs less than endoscopic CTR, and the clinic procedure room or ambulatory surgery center is cheaper than the ambulatory surgery center, which is less than the hospital. Patient satisfaction can be increased by making office visits more patient-centered and improving the quality of dialogue between the surgeon and patient. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00305898183009
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http://dx.doi.org/10.1016/j.ocl.2018.06.005DOI Listing
October 2018
13 Reads

Ultrasonographic imaging of the effects of continuous, pulsed or sham ultrasound treatments on carpal tunnel syndrome: A randomized controlled study.

J Back Musculoskelet Rehabil 2018 ;31(5):981-989

Department of Physical Medicine and Rehabilitation, Pamukkale University, Denizli, Turkey.

Background: Clinical and electrophysiological effects of therapeutic ultrasound (US) were researched in many studies on patients with CTS with conflicting results.

Objective: To assess the effects of continuous and pulsed US treatments by ultrasonographic imaging in addition to clinical and electrophysilogical parameters in patients with carpal tunnel syndrome (CTS).

Method: Fifty-four patients with idiopathic CTS were randomly divided into three groups. Read More

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http://dx.doi.org/10.3233/BMR-160652DOI Listing
January 2019
3 Reads

Effect of PEA-OXA on neuropathic pain and functional recovery after sciatic nerve crush.

J Neuroinflammation 2018 Sep 14;15(1):264. Epub 2018 Sep 14.

Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno D'Alcontres, no 31, 98166, Messina, Italy.

Background: Animal models of sciatic nerve injury are commonly used to study neuropathic pain as well as axon regeneration. Inflammation/immune response at the site of nerve lesion is known to be an essential trigger of the pathological changes that have a critical impact on nerve repair and regeneration; moreover, the damage to peripheral nerve can cause a loss of sensory function and produces a persistent neuropathic pain. N-Acylethanolamines (NAEs) involve a family of lipid molecules existent in animal and plant, of which is N-palmitoylethanolamide (PEA) that arouses great attention owing to its anti-inflammatory, analgesic, and neuroprotective activities. Read More

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http://dx.doi.org/10.1186/s12974-018-1303-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137737PMC
September 2018
3 Reads