21,574 results match your criteria Mononeuritis Multiplex

[Local anaesthesia and steroid blockades for carpal tunnel syndrome in pregnancy].

Ugeskr Laeger 2021 05;183(22)

The possible impact on the foetus must always be taken into account, whenever non-conservative strategies are considered in pregnancy. As to carpal tunnel syndrome, surgery is usually reserved for severe cases, or when steroid blockades have been insufficient. If only pharmacological considerations are taken into account, surgery with local anaesthetics may however be preferred over blockades. Read More

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Efficacy of a fixed combination of Palmitoylethanolamide and acetyl-l-carnitine (PEA + ALC FC) in the treatment of Neuropathies secondary to Rheumatic Diseases.

Minerva Med 2021 May 31. Epub 2021 May 31.

Rheumatology Unit, Azienda Ospedaliera Universitaria Città Della Salute e della Scienza di Torino, Turin, Italy.

Background: The neurologic complications of rheumatic diseases (RDs) are highly variable, and their manifestations are linked to the pathogenesis and clinical phenotype of the specific RDs. In rheumatoid arthritis, for example, the peripheral nervous system is most commonly involved and mononeuritis multiplex, nerve entrapment and vascultitic sensorimotor neuropathies are not uncommon. Often the therapy for these disorders is not simple and is characterized by the use of different drugs. Read More

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Use of conservative therapy before and after surgery for carpal tunnel syndrome.

BMC Musculoskelet Disord 2021 May 26;22(1):484. Epub 2021 May 26.

Department of Physical Medicine and Rehabilitation, Central Finland Central Hospital, Jyväskylä, Finland.

Background: Conservative therapies are typically offered to individuals who experience mild or intermittent symptoms of carpal tunnel syndrome (CTS) or postoperatively to subjects who have undergone carpal tunnel release. Although long-term studies report mostly positive results for carpal tunnel release, knowledge on the need for conservative treatments following surgery is scarce. The aim of this retrospective cohort study was to examine the use of conservative therapies before and after carpal tunnel releasing surgery. Read More

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Effects of wrist extension on median nerve and flexor tendon excursions in patients with carpal tunnel syndrome: a case control study.

BMC Musculoskelet Disord 2021 May 24;22(1):477. Epub 2021 May 24.

Department of Physical Medicine and Rehabilitation, Taipei Tzuchi Hospital, Buddhist Tzuchi Medical Foundation, No.289, Jianguo Rd., Xindian Dist., New Taipei City, 231, Taiwan.

Background: Reduced gliding ability of the median nerve in the carpal tunnel has been observed in patients with carpal tunnel syndrome (CTS). The purpose of this study was to evaluate the gliding abilities of the median nerve and flexor tendon in patients with CTS and healthy participants in the neutral and 30° extended positions of the wrist and to compare the gliding between the finger flexion and extension phases.

Methods: Patients with CTS and healthy participants were consecutively recruited in a community hospital. Read More

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Amelioration of lower limb pain and foot drop with 10 kHz spinal cord stimulation: A case series.

J Int Med Res 2021 May;49(5):3000605211005954

The Spine Centre of SE Georgia, Brunswick, GA, USA.

There are limited treatment options for patients with foot drop and associated lower back and/or leg pain. We present a case series of three patients who received permanent implantation of 10 kHz spinal cord stimulation (10 kHz SCS) devices. Following treatment, all patients reported sustained improvements in lower back and leg pain, foot mechanics and function which resulted in increased mobility and cessation of opioid use for pain management. Read More

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Neurological manifestations of polyarteritis nodosa: a tour of the neuroaxis by case series.

BMC Neurol 2021 May 21;21(1):205. Epub 2021 May 21.

Weill Institute for Neurosciences, University of California, San Francisco, California, USA.

Background: Heterogenous central nervous system (CNS) neurologic manifestations of polyarteritis nodosa (PAN) are underrecognized. We review three cases of patients with PAN that illustrate a range of nervous system pathology, including the classical mononeuritis multiplex as well as uncommon brain and spinal cord vascular manifestations.

Case Presentation: Case 1 presented with mononeuritis multiplex and characteristic skin findings. Read More

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Surgical treatment of carpal tunnel syndrome in advanced-stage upper extremity lymphedema: A case report.

Medicine (Baltimore) 2021 May;100(20):e25872

Department of Plastic Surgery, Korea University College of Medicine, Seoul, South Korea.

Rationale: Despite significant advances in microsurgical techniques, simultaneous release of transverse carpal ligament (TCL) and lymphovenous anastomosis (LVA) surgeries may be effective for treatment of carpal tunnel syndrome (CTS) and advanced-stage lymphedema. This case report describes the successful treatment of lymphedema with LVA in a patient with CTS and advanced-stage lymphedema.

Patient Concerns: A 60-year-old female patient was referred to our lymphedema clinic with a 12-year history of chronic, acquired, right upper extremity lymphedema and CTS following right mastectomy and axillary lymph node dissection and adjuvant chemoradiotherapy for treating breast cancer. Read More

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[Manual medicine, manual treatment : Principles, mode of action, indications and evidence].

Hermann Locher

Unfallchirurg 2021 Jun 19;124(6):433-445. Epub 2021 May 19.

Zentrum für Orthopädie und Unfallchirurgie, Lindauerstr. 16, 88069, Tettnang, Deutschland.

Manual medicine is the medical discipline that comprehensively deals with the diagnosis, treatment and prevention of reversible functional disorders of the musculoskeletal system and other related organ systems. The article illustrates the neuroanatomical and neurophysiological basic elements and mechanisms of manual medical diagnostics and treatment. Based on the most recent literature and in consideration of various scientific guidelines, the evidence-based effectiveness of manual medical procedures is presented. Read More

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Neuromuscular Ultrasound: Indications in the Electrodiagnostics Laboratory.

Am J Phys Med Rehabil 2021 May 13. Epub 2021 May 13.

Department of Physical Medicine and Rehabilitation, Albany Medical College, Albany, New York, USA Department of Family Medicine, Larner Medical College at the University of Vermont, Burlington, Vermont, USA Adirondack Rehabilitation Medicine, PLLC, Queensbury, New York, USA Department of Neurology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA Department of Physical Medicine and Rehabilitation, The Brody School of Medicine at East Carolina University, Greenville, South Carolina, USA.

Abstract: Accurate assessment of neuromuscular disorders is critical to facilitate timely treatment and achieve the best outcomes. Historically, electrodiagnostic (EDX) studies have filled this role, but recently, neuromuscular ultrasound (NMUS) is being used in the EDX lab. This review discusses the uses of NMUS in the EDX lab that have strong evidence, emphasizing those that could be adopted in a typical EDX lab with a reasonable level of equipment and training. Read More

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Hypocomplementemic urticarial vasculitis syndrome presenting with bilateral scleritis.

BMJ Case Rep 2021 May 10;14(5). Epub 2021 May 10.

Department of Immunology, Canberra Health Services, Garran, Australian Capital Territory, Australia.

Hypocomplementemic urticarial vasculitis syndrome (HUVS) is a rare autoimmune disorder characterised by recurrent urticarial lesions and acquired hypocomplementemia with systemic manifestations. The authors present the case of a 70-year-old man who presented to the ophthalmology clinic with bilateral scleritis and ocular hypertension. He was diagnosed with HUVS after a 6-month period of bilateral scleritis, vestibulitis, significant weight loss, mononeuritis multiplex and recurrent urticarial vasculitis with pronounced persistent hypocomplementemia and the presence of anti-C1q antibodies. Read More

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Primary elbow osteoarthritis presenting as ulnar nerve palsy with claw hand.

BMJ Case Rep 2021 May 6;14(5). Epub 2021 May 6.

Plastic Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

A 59-year-old woman was referred with weakness, paraesthesia, numbness and clawing of the little and ring fingers for the last 2 years. MRI of the cervical spine was normal and nerve conduction velocity revealed abnormality of the ulnar nerve. Ultrasound and MRI showed medial osteophytes and effusion of the elbow joint with stretched and thinned ulnar nerve in the cubital tunnel. Read More

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ANCA-Negative Churg-Strauss Syndrome Presenting as Bilateral Central Retinal Artery Occlusion: A Case Report

Turk J Ophthalmol 2021 04;51(2):127-130

Birjand University of Medical Sciences Valiasr Hospital, Department of Internal Medicine, Birjand, Iran

A 42-year-old man with undiagnosed Churg-Strauss syndrome (CSS) developed bilateral central retinal artery occlusion (CRAO). His medical history included bronchial asthma and irregular prednisolone usage but no atherosclerotic risk factors. At presentation, visual acuity (VA) was hand motion in the right eye and counting fingers in left eye. Read More

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Investigation of Neuropathology after Nerve Release in Chronic Constriction Injury of Rat Sciatic Nerve.

Int J Mol Sci 2021 Apr 29;22(9). Epub 2021 Apr 29.

Division of Plastic and Reconstructive Surgery, Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan.

Peripheral compressive neuropathy causes significant neuropathic pain, muscle weakness and prolong neuroinflammation. Surgical decompression remains the gold standard of treatment but the outcome is suboptimal with a high recurrence rate. From mechanical compression to chemical propagation of the local inflammatory signals, little is known about the distinct neuropathologic patterns and the genetic signatures after nerve decompression. Read More

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Immune Axonal Neuropathies Associated With Systemic Autoimmune Rheumatic Diseases.

Front Pharmacol 2021 14;12:610585. Epub 2021 Apr 14.

Colentina-Research and Development Center, Colentina Clinical Hospital, Bucharest, Romania.

Immune axonal neuropathies are a particular group of immune-mediated neuropathies that occasionally accompany systemic autoimmune rheumatic diseases such as connective tissue dissorders and primary systemic vasculitides. Apart from vasculitis of vasa nervorum, various other mechanisms are involved in their pathogenesis, with possible therapeutic implications. Immune axonal neuropathies have highly heterogeneous clinical presentation and course, ranging from mild chronic distal sensorimotor polyneuropathy to severe subacute mononeuritis multiplex with rapid progression and constitutional symptoms such as fever, malaise, weight loss and night sweats, underpinning a vasculitic process. Read More

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Treatment of meralgia paresthetica (Lateral Femoral Cutaneous Neuropathy): A meta-analysis of ultrasound-guided injection versus surgery.

Eur J Radiol 2021 Jun 26;139:109736. Epub 2021 Apr 26.

Department of Health Sciences (DISSAL). University of Genoa, Genoa, Italy. Electronic address:

Purpose: To compare ultrasound (US)-guided injections and surgery for the treatment of meralgia paresthetica (lateral femoral cutaneous neuropathy).

Methods: Two reviewers, independently, up to 10 October 2020 retrieved Studies that assessed the outcome of US-guided injections and surgery for the treatment of meralgia paresthetica from major medical libraries. Predefined inclusion and exclusion criteria were adopted. Read More

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Primary Radial Nerve Exploration Determined by Ultrasound in Pediatric Supracondylar Humerus Fracture: A Report of Two Cases.

J Hand Surg Asian Pac Vol 2021 Jun;26(2):284-289

Department of Hand Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.

We report two pediatric cases of radial nerve palsy caused by supracondylar fracture of the humerus requiring nerve exploration. The children had comparable conditions, palsy types (complete motor and partial sensory) and radiographic findings. The fracture in the first case was managed conservatively with closed reduction and percutaneous pinning but, while the patient eventually recovered from the partial sensory palsy, her motor palsy remained unchanged. Read More

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Ultrasonographic Measurement of the Median Nerve Transverse Diameter at the Wrist for Diagnosing Carpal Tunnel Syndrome.

J Hand Surg Asian Pac Vol 2021 Jun;26(2):223-228

Department of Orthopedic Surgery, Goto Orthopedic Hand Clinic, Sendai, Japan.

Ultrasonographically measuring the median nerve cross-sectional area (MN-CSA) is a useful and complementary method for diagnosing carpal tunnel syndrome (CTS). This study investigated the usefulness of the median nerve transverse diameter (MN-TD) as a simpler and easier technique than MN-CSA for diagnosing CTS severity. We examined 145 hands from 101 patients with CTS and 114 age- and gender-matched control hands. Read More

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Novel steroid infiltration technique of the carpal tunnel.

BMJ Case Rep 2021 Apr 28;14(4). Epub 2021 Apr 28.

Department of Plastic Surgery, Galway University Hospitals, Galway, Ireland.

This report describes a novel technique of steroid infiltration of the wrist to treat symptomatic carpal tunnel syndrome. Our approach potentially reduces direct trauma to the median nerve when compared with current conventional techniques. The use of a cannula allows infiltration directly into the carpal tunnel and advancement of the blunt tip minimises the risk of sharp trauma to the median nerve and adjacent tendons. Read More

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Lumbosacral plexopathy due to pelvic hematoma after extracorporeal membrane oxygenation: A case report.

Medicine (Baltimore) 2021 Apr;100(17):e25698

Department of Neurology, Washington University School of Medicine, Saint Louis, MO.

Rationale: Peripheral nerve injury related to vascular complications associated with extracorporeal membrane oxygenation (ECMO) is perhaps underappreciated. Compared to the well-described central nervous system complications of ECMO, brachial plexopathy and lumbosacral plexopathy have rarely been reported. We report this case to heighten awareness of lumbosacral plexus injury due to pelvic hematoma formation after ECMO. Read More

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Intra-articular entrapment of an avulsed common peroneal nerve following atypical knee fracture-dislocation.

BMJ Case Rep 2021 Apr 26;14(4). Epub 2021 Apr 26.

Department of Trauma & Orthopaedic Surgery, University Hospital Galway, HSE West, Galway, Ireland.

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Multiple mononeuritis with peripheral blood eosinophilia in a patient with Q fever: An unusual presentation: Case report and review of the literature.

J Infect Chemother 2021 Apr 23. Epub 2021 Apr 23.

Department of Internal Medicine, Evangelismos General Hospital, 45 - 47 Ypsilantou St, 10676, Athens, Greece.

Coxiella burnetii is a gram-negative bacterium that typically lives and multiplies within monocytes and macrophages of the host, being the etiologic agent of the zoonosis Q fever. Q fever is usually divided into acute and chronic forms, with a significant percentage of patients being asymptomatic. In the wide spectrum of the disease, neurological involvement seems to be extremely rare and peripheral neuropathy presenting with mononeuritis multiplex is one of the possible presentations with low rates of occurrence. Read More

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Health economic evaluation of different treatment strategies for peripheral entrapment mononeuropathies: a systematic review.

Expert Rev Pharmacoecon Outcomes Res 2021 May 5:1-10. Epub 2021 May 5.

College of Pharmaceutical Sciences, Soochow University, Suzhou, China.

: In this era of cost-conscious health systems, it is of utmost importance to identify and establish the most cost-effective treatment option. However, in the case of peripheral entrapment mononeuropathies there is alack of data regarding economically effective treatment strategies. Therefore, the objective was to conduct an economic evaluation including both costs and benefits of various treatment strategies applied to peripheral entrapment mononeuropathies to estimate the relative cost-effective treatment regimens. Read More

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Determining the utility of minimum F-wave latency alterations in the electrodiagnosis of ulnar neuropathy at the elbow.

Arq Neuropsiquiatr 2021 03;79(3):195-200

Gaziosmanpaşa Taksim Education and Research Hospital, Department of Neurology, Istanbul, Turkey.

Background: Ulnar neuropathy at the elbow (UNE) is the second most common entrapment neuropathy. There is little information about the application of F-wave studies for evaluation of UNE.

Objective: The aim of this study was to evaluate the diagnostic value of minimum F-wave (F-min) latency alterations by comparing this with nerve conduction analyses in UNE-suspected patients. Read More

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Numbness of the lower lip following urological surgery under general anesthesia - A case report.

Anesth Pain Med (Seoul) 2021 Apr 8;16(2):201-204. Epub 2021 Apr 8.

Department of Anesthesiology and Pain Medicine, Inje University Sanggye Paik Hospital, Seoul, Korea.

Background: Peripheral nerve injury is a complication that can occur after general anesthesia. It significantly impairs the patient's quality of life and may lead to permanent disability. Nerves in several areas can be damaged during the perioperative period, but it is very rare that numbness of the lower lip is caused after general anesthesia. Read More

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Diagnostic accuracy of sensory and motor tests for the diagnosis of carpal tunnel syndrome: a systematic review.

BMC Musculoskelet Disord 2021 Apr 7;22(1):337. Epub 2021 Apr 7.

School of Physical Therapy, Faculty of Health Science, Elborn College, Western University, London, ON, Canada.

Background: Carpal tunnel syndrome (CTS) is the most common entrapment mononeuropathy of the upper extremity. The previous systematic review of the diagnostic tests for CTS was outdated. The objective of this study was to compile and appraise the evidence on the accuracy of sensory and motor tests used for the diagnosis of CTS. Read More

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Pembrolizumab-Associated CD8 Vasculitic Mononeuritis Multiplex in a Patient With Mesothelioma.

Neurol Neuroimmunol Neuroinflamm 2021 07 6;8(4). Epub 2021 Apr 6.

From the Department of Neurology (M.C.B., M.K., A.F., S.H.-F.); Department of Hematology and Oncology (M.J.); Department of Dermatology (L.F.); Department of Pathology (R.R.), Cantonal Hospital, St. Gallen; Department of Pathology (S.F.), University Hospital, Basel; and Department of Neurology and Department of Hematology and Oncology (T.H.), Cantonal Hospital St. Gallen, Switzerland.

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Peripheral nervous system manifestations of rheumatological diseases.

J Neurol Sci 2021 05 27;424:117421. Epub 2021 Mar 27.

University of Virginia, Department of Neurology, Charlottesville, VA, USA.

Rheumatological diseases result in immune-mediated injury to not only connective tissue, but often components of the peripheral nervous system. These overlap conditions can be broadly categorized as peripheral neuropathies and overlap myositis. The peripheral neuropathies are distinctive as many have unusual presentations such as non-length-dependent, small fiber neuropathies and sensory neuronopathies (both due to dorsal root ganglia dysfunction), multiple mononeuropathies (e. Read More

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"Person-in-the-Barrel" Syndrome: A Case Report of Bilateral Arm Paresis Due to Vasculitis With a Review of Pathological Mechanisms.

Cureus 2021 Feb 28;13(2):e13607. Epub 2021 Feb 28.

Neurology, Flowers Medical Group, Dothan, USA.

"Person-in-the-barrel" syndrome is a descriptive term for bilateral arm (brachial) paresis in the absence of lower extremity (crural) weakness or bulbar (medullary) weakness. This phenomenon is associated with various descriptive terms such as "distal field infarction", "flail limbs", and "cruciate paralysis". Arriving at a specific diagnosis is a fascinating exercise in anatomical localization. Read More

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February 2021

[Triple needling combined with thermo-electroacupuncture at Huantiao (GB 30) for trunk-sciatica].

Zhongguo Zhen Jiu 2021 Mar;41(3):275-8

Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China.

Objective: To compared the clinical effect between triple needling combined with thermo-electroacupuncture at Huantiao (GB 30) and triple needling combined with electroacupuncture at Huantiao (GB 30) for trunk-sciatica.

Methods: A total of 56 patients with trunk-sciatica were randomized into a triple needling combined with thermo-electroacupuncture group and a triple needling combined with electroacupuncture group, 28 cases in each group. In the triple needling combined with thermo-electroacupuncture group, triple needling combined with thermo-electroacupuncture at Huantiao (GB 30) was applied. Read More

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[Effect of moxibustion on expression of GAP-43 in sciatic nerve trunk and ventral horn of spinal cord of rats with primary sciatica and its nerve repair function].

Zhongguo Zhen Jiu 2021 Feb;41(2):183-8

Department of Geriatrics, Second Affiliated Hospital of Anhui University of CM, Hefei 230000, China.

Objective: To observe the effect of moxibustion at "Huantiao" (GB 30) on the expression of growth-associated protein-43 (GAP-43) in the sciatic nerve trunk and ventral horn of spinal cord (L-L) in rats with primary sciatica, and to explore the mechanism of moxibustion in improving primary sciatica.

Methods: A total of 48 healthy male SD rats were randomly divided into a normal group, a sham operation group, a model group and a moxibustion group, 12 rats in each group. The rat model of primary sciatic pain was established by chronic constriction injury (CCI) of the sciatic nerve in the model group and the moxibustion group. Read More

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February 2021