19,698 results match your criteria Mononeuritis Multiplex


Mononeuritis multiplex: an uncommon neurological manifestation of cytomegalovirus reactivation in an HIV-infected patient.

BMC Infect Dis 2018 Nov 12;18(1):554. Epub 2018 Nov 12.

Infectious Diseases Department, Centro Hospitalar de São João, Alameda Professor Hernâni Monteiro, 4200-319, Porto, Portugal.

Background: Cytomegalovirus (CMV) reactivation with neurological involvement in patients with acquired immunodeficiency syndrome (AIDS) is increasingly rare since the introduction of antiretroviral therapy (ART). Manifestations include encephalitis, myelitis, polyradiculopathy and, less commonly, mononeuritis multiplex (MNM). We report a case of disseminated CMV disease with gastrointestinal and peripheral and central nervous system involvement in a patient with AIDS, manifesting primarily as MNM. Read More

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November 2018
5 Reads

Report of an Isolated L5 Radiculopathy Caused by an L2-3 Disc Herniation and Review of the Literature.

Cureus 2018 Apr 30;10(4):e2552. Epub 2018 Apr 30.

Neurological Surgery, UC Health, Cincinatti, USA.

Intervertebral disc herniation is a common cause of radiculopathy. Disc herniations occurring in the lumbar spine typically affect the nerve root exiting under the pedicle of the vertebral body, one level caudal. However, in rare cases, a disc herniation can cause remote isolated radicular symptoms. Read More

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April 2018
6 Reads

Elbow Surgery in Athletes.

Sports Med Arthrosc Rev 2018 Dec;26(4):181-184

Andrews Sports Medicine, Birmingham, AL.

Injuries and disorders of the elbow in athletes are common especially among throwing athletes. Common injuries encountered in the throwing athlete include ulnar collateral ligament injuries, ulnar neuritis, capitellar osteochondritis dissecans, valgus extension overload with posterior olecranon impingement, olecranon stress fracture, and loose bodies. A thorough knowledge of both the functional anatomy as well as throwing biomechanics are required to properly diagnosis and treat these problems. Read More

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December 2018
1 Read

Peroneal nerve mononeuropathy associated with herpes zoster. A case report.

Neurol Sci 2018 Oct 31. Epub 2018 Oct 31.

Neuromuscular Unit, Hospital Universitario del Sureste, Ronda del Sur 10, E28500, Arganda del Rey (Madrid), Spain.

Background: Sensory or motor syndromes, especially mononeuropathies, are infrequent complications of herpes zoster.

Case Report: We describe a 77-year-old woman who developed a severe right common peroneal nerve mononeuropathy with clinical onset 10 days after a vesicular rash consistent with herpes zoster in the territory of distribution of this nerve.

Conclusion: To our knowledge, peroneal nerve mononeuropathy associated with herpes zoster has not been reported previously. Read More

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October 2018
4 Reads

Neuroborreliosis.

Authors:
John J Halperin

Neurol Clin 2018 Nov;36(4):821-830

Department of Neurosciences, Overlook Medical Center, 99 Beauvoir Avenue, Summit, NJ 07902, USA; Sidney Kimmel Medical College, Thomas Jefferson University, 1025 Walnut Street, Philadelphia, PA 19107, USA. Electronic address:

Neurologic manifestations of nervous system infection with Borrelia burgdorferi, Borrelia garinii, and Borrelia afzelii are qualitatively similar, and include lymphocytic meningitis, cranial neuritis, radiculoneuritis, and other focal or multifocal mononeuropathies. Parenchymal central nervous system (CNS) infection occurs rarely. Neurobehavioral changes are common, but are rarely evidence of CNS infection. Read More

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November 2018
1 Read

The clinical and cost-effectiveness of corticosteroid injection versus night splints for carpal tunnel syndrome (INSTINCTS trial): an open-label, parallel group, randomised controlled trial.

Lancet 2018 10;392(10156):1423-1433

Arthritis Research UK Primary Care Centre, Research Institute for Primary Care and Health Sciences, Keele University, Keele, UK; Haywood Academic Rheumatology Centre, Haywood Hospital, Staffordshire and Stoke-on-Trent Partnership NHS Trust, Stoke-on-Trent, UK. Electronic address:

Background: To our knowledge, the comparative effectiveness of commonly used conservative treatments for carpal tunnel syndrome has not been evaluated previously in primary care. We aimed to compare the clinical and cost-effectiveness of night splints with a corticosteroid injection with regards to reducing symptoms and improving hand function in patients with mild or moderate carpal tunnel syndrome.

Methods: We did this randomised, open-label, pragmatic trial in adults (≥18 years) with mild or moderate carpal tunnel syndrome recruited from 25 primary and community musculoskeletal clinics and services. Read More

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October 2018
9 Reads

Steroid injection or wrist splint for first-time carpal tunnel syndrome?

Authors:
Isam Atroshi

Lancet 2018 10;392(10156):1383-1384

Department of Clinical Sciences and Department of Orthopaedics, Lund University, Lund, Sweden; Department of Orthopaedics, Hässleholm-Kristianstad, Hässleholm SE 28125, Sweden. Electronic address:

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October 2018
1 Read

A Very Rare Complication of Hepatitis A Infection: Acute Myocarditis-A Case Report with Literature Review.

Case Rep Med 2018 13;2018:3625139. Epub 2018 Sep 13.

Internal Medicine Department, Beaumont Hospital, Royal Oak, MI, USA.

Hepatitis A is a common viral infection with a benign course but in rare cases can progress to acute liver failure. It usually presents with abdominal pain, nausea, vomiting, diarrhea, jaundice, anorexia, or asymptomatically, but it can also present atypically with relapsing hepatitis and prolonged cholestasis. In addition, extrahepatic manifestations have been reported, including urticarial and maculopapular rash, acute kidney injury, autoimmune hemolytic anemia, aplastic anemia, acute pancreatitis, mononeuritis, reactive arthritis, glomerulonephritis, cryoglobulinemia, Guillain-Barre syndrome, and pleural or pericardial effusion. Read More

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September 2018
3 Reads

Rates of Carpal Tunnel Syndrome in a State Workers' Compensation Information System, by Industry and Occupation - California, 2007-2014.

MMWR Morb Mortal Wkly Rep 2018 Oct 5;67(39):1094-1097. Epub 2018 Oct 5.

Carpal tunnel syndrome (CTS) occurs when the median nerve becomes compressed as it passes through the wrist within the carpal tunnel, resulting in pain, tingling, weakness, or numbness in the hand or the wrist. Occupational risk factors for CTS include engaging in work activities that require forceful, repetitive tasks, prolonged use of the hands or wrists in an awkward posture, or vibration (1). To assess trends and identify high-risk industries and occupations for CTS, the California Department of Public Health (CDPH) analyzed California workers' compensation claims for CTS by industry (2007-2014) and occupation (2014) and calculated rates per full-time equivalent (FTE) worker. Read More

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October 2018
2 Reads

Evaluation of dexamethasone treated mesenchymal stem cells for recovery in neurotmesis model of peripheral nerve injury.

Neurol Res 2018 Dec 22;40(12):1060-1070. Epub 2018 Sep 22.

e Department of Physical Medicine, and Rehabilitation , Iran University of Medical Sciences , Tehran , Iran.

Objective: Peripheral nerve injuries comprise significant portion of the nervous system injuries. Although peripheral nerves show some capacity of regeneration after injury, the extent of regeneration is not remarkable. The present study aimes to evaluate the regeneration of transected sciatic nerve by a therapeutic value of dexamethasone (DEX) associated with cell therapy (Cell) and biodegradable membrane (Mem) in rat. Read More

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December 2018
1 Read

Unusual variant of distal biceps femoris muscle associated with common peroneal entrapment neuropathy: A cadaveric case report.

Medicine (Baltimore) 2018 Sep;97(38):e12274

Department of Anatomy and Cell Biology, Graduate School of Medicine, Kangwon National University, Kangwon.

Rationale: The anatomical variant of the distal biceps femoris muscle with regard to common peroneal nerve entrapment neuropathy (CPNe) was suggested through magnetic resonance images (MRI) study.

Patient Concerns: An unusual variant of distal biceps femoris muscle was observed in 78 years old male cadaver.

Diagnoses: The short head of biceps femoris muscle (SHBFM) was extended more distal and posteriorly. Read More

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September 2018
1 Read

Analysis of the muscle tissue of Wistar rats submitted to the sciatic nerve compression model and cryotherapy.

Einstein (Sao Paulo) 2018 Sep 17;16(3):eAO4206. Epub 2018 Sep 17.

Universidade Estadual do Oeste do Paraná, Cascavel, PR, Brazil.

Objective: To evaluate the effects of right sciatic nerve compression and cryotherapy on muscle tissue.

Methods: We used 42 male Wistar rats, subdivided in the following Groups Control, Injury 3, Injury 8 and Injury 15 submitted to nerve compression and euthanized in the 3rd, 8th and 15th day after surgery. The Cryotherapy Injury 3 was entailed treatment with cryotherapy by immersion of the animal in recipient for 20 minutes during 1 day, then animals were euthanized at the 3rd day after surgery, and the Cryotherapy Injury 8 and the Cryotherapy Injury 15 was treated for 6 days, and euthanized at the 8th and 15th day after surgery. Read More

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September 2018
1 Read

Cost, Value, and Patient Satisfaction in Carpal Tunnel Surgery.

Orthop Clin North Am 2018 Oct 16;49(4):503-507. Epub 2018 Aug 16.

Campbell Clinic-University of Tennessee, Department of Orthopaedic Surgery and Biomedical Engineering, 1211 Union Avenue, Suite 510, Memphis, TN 38104, USA.

The cost of carpal tunnel release (CTR) surgery can be decreased and patient satisfaction increased by a few relatively simple changes. Although cost estimates vary in the literature, most investigators agree that open CTR costs less than endoscopic CTR, and the clinic procedure room or ambulatory surgery center is cheaper than the ambulatory surgery center, which is less than the hospital. Patient satisfaction can be increased by making office visits more patient-centered and improving the quality of dialogue between the surgeon and patient. Read More

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October 2018
11 Reads

Bilateral sciatic neuropathy with severe rhabdomyolysis following venlafaxine overdose: A case report.

Medicine (Baltimore) 2018 Sep;97(37):e12220

Department of Rehabilitation Medicine, Daegu Fatima Hospital, Daegu, Republic of Korea.

Rationale: Venlafaxine is an antidepressant and anxiolytic agent that functions by inhibiting central serotonin and norepinephrine reuptake, and it is a relatively recently introduced drug. In particular, overdose of venlafaxine has been reported to cause severe cardiac toxicity including ventricular tachycardia, prolongation of QT interval, and seizure or severe muscular injury. However, reports describing venlafaxine-induced rhabdomyolysis with neuropathy remain scarce. Read More

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September 2018
1 Read

Peripheral nerve injuries in the pediatric population: a review of the literature. Part II: entrapment neuropathies.

Childs Nerv Syst 2018 Sep 12. Epub 2018 Sep 12.

Department of Plastic Surgery, Hospital Universitario Central de Asturias, Oviedo, Spain.

Introduction: Entrapment neuropathies are infrequent in children, and therefore remain unrecognized. The incidence of radial, median, and cubital mononeuropathies are all similar. Despite the rarity of such cases, extensive, albeit scattered, literature has accumulated concerning entrapment neuropathies in children. Read More

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September 2018
1 Read

Sciatic neuropathy caused by a pressure ulcer: A case report.

Medicine (Baltimore) 2018 Sep;97(36):e12254

Rationale: Sciatic neuropathy has various causes; however, cases in which a pressure ulcer led to sciatic neuropathy have not been reported to date.

Patient Concerns: A 33-year-old woman with no pre-existing mobility problems visited our department with the chief complaint of an extensive pressure ulcer and necrosis in her right buttock. She had a medical history of being bedridden for 2 days while in a coma due to a drug overdose 2 months previously. Read More

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September 2018
1 Read

[A case of multiple cerebral hemorrhage caused by sudden increase of eosinophil in a patient with eosinophilic granulomatosis with polyangiitis].

Rinsho Shinkeigaku 2018 Sep 31;58(9):565-569. Epub 2018 Aug 31.

Department of Neurology, Nagaoka Red Cross Hospital.

A 42-year-old woman with bronchial asthma was admitted to our hospital due to sensory dominant mononeuritis multiplex lasting for more than 6 months. At that time, her eosinophil count was 761/μl and her sural nerve biopsy showed no findings suggestive of vasculitis. Four months later, she experienced sudden convulsions and right hemiparesis due to left lobular parietal subcortical hemorrhage, when her eosinophil count was elevated to 3,257/μl. Read More

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September 2018
1 Read

[Treatment of humerus diaphyseal fractures using Hackethal's retrograde centro-medullary bundle nailing: about 54 cases].

Pan Afr Med J 2018 17;30:38. Epub 2018 May 17.

Orthopedic Surgery and Traumatology, Military Hospital Moulay Ismail, Meknes, Morocco.

We here report 54 cases of humerus diaphyseal fractures treated via Hackethal's bundle nailing. We observed 3 cases of radial nerve palsy. Therapeutic abstention associated with monitoring was the applied attitude toward these patients on presentation to the Emergency Department. Read More

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September 2018
1 Read

Paraneoplastic Mononeuritis Multiplex: A Unique Presentation of Non-Hodgkin Lymphoma.

Cureus 2018 Jun 26;10(6):e2885. Epub 2018 Jun 26.

Pathology, Shifa International Hospital, Islamabad, PAK.

Mononeuritis multiplex (MM) is a common variant of a peripheral neuropathy which is characterized by neurological discrepancies that afflict two noncontiguous nerve systems. It is mostly associated with systemic illnesses such as diabetes mellitus, vasculitis, systemic lupus erythematosus (SLE), viral infections including human immunodeficiency virus (HIV) and paraneoplastic syndromes. Lymphoma is a common antecedent to paraneoplastic syndromes that cause peripheral neuropathies but a specific presentation of MM is a rare predicament per our literature analysis. Read More

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June 2018
6 Reads

Reversible reddish skin color change in a patient with compressive radial neuropathy.

BMC Neurol 2018 Aug 21;18(1):120. Epub 2018 Aug 21.

Department of Neurology, Seoul Paik Hospital, Inje University College of Medicine, Mareunnae-ro 9, Jung-gu, Seoul, 04551, Republic of Korea.

Background: The motor and sensory symptoms caused by compressive radial neuropathy are well-known, but the involvement of the autonomic nervous system or the dermatologic symptoms are less well known. We report an unusual case of compressive radial neuropathy with reversible reddish skin color change.

Case Presentation: A 42-year-old man was referred for left wrist drop, finger drop and a tingling sensation over the lateral dorsum of the left hand. Read More

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August 2018
4 Reads
2.040 Impact Factor

Involvement of advillin in somatosensory neuron subtype-specific axon regeneration and neuropathic pain.

Proc Natl Acad Sci U S A 2018 09 20;115(36):E8557-E8566. Epub 2018 Aug 20.

Taiwan International Graduate Program in Molecular Medicine, National Yang-Ming University and Academia Sinica, 112 Taipei, Taiwan;

Advillin is a sensory neuron-specific actin-binding protein expressed at high levels in all types of somatosensory neurons in early development. However, the precise role of advillin in adulthood is largely unknown. Here we reveal advillin expression restricted to isolectin B4-positive (IB4) neurons in the adult dorsal root ganglia (DRG). Read More

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September 2018
1 Read

Childhood- versus Adult-Onset Polyarteritis Nodosa Results from the French Vasculitis Study Group Registry.

Autoimmun Rev 2018 Oct 14;17(10):984-989. Epub 2018 Aug 14.

National Referral Center for Rare Systemic Autoimmune Diseases, Department of Internal Medicine, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris (APHP), Université Paris Descartes, Paris, France. Electronic address:

Objective: To investigate differences between childhood (cPAN)- and adult-onset polyarteritis nodosa (aPAN) patients.

Methods: cPAN patients' clinical findings at onset and outcomes were compared to those of aPAN patients from the French Vasculitis Study Group registry matched for year of enrollment and initial systemic versus cutaneous disease. Their information on medications, disease activity and damage were collected. Read More

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October 2018
21 Reads

Retrospective analysis of ocular neuropathies in diabetic dogs following cataract surgery.

Vet Ophthalmol 2018 Aug 10. Epub 2018 Aug 10.

BluePearl Veterinary Partners, Tampa, FL, USA.

Objectives: To describe and compare the cumulative incidence and clinical progression of ocular neuropathies in diabetic dogs vs nondiabetic dogs following cataract surgery.

Methods: Medical records of 196 diabetic and 442 nondiabetic dogs who underwent cataract surgery between 2004 and 2015 were reviewed. The percentage of patients affected by neuropathy and potential risk factors were compared between groups. Read More

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August 2018
10 Reads

Management of multiple neurological complications in mixed connective tissue disease: A case report.

Medicine (Baltimore) 2018 Aug;97(31):e11360

Department of Neurology and Neuroscience Center, The First Hospital of Jilin University.

Rationale: Mixed connective tissue disease (MCTD) refers to an overlapping condition of different autoimmune disorders such as systemic lupus erythematosus, cutaneous systemic sclerosis, rheumatoid arthritis, polymyositis, and dermatomyositis. However, MCTD manifesting as transverse myelitis is extremely rare. Herein, we report a case of MCTD with both central and peripheral nervous system involvement. Read More

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August 2018
2 Reads

Modified simple decompression of ulnar nerve in the treatment of cubital tunnel syndrome: Report of a series of cases.

Authors:
M Balevi S Ozturk

Niger J Clin Pract 2018 Aug;21(8):974-978

Department of Neurosurgery, School of Medicine, Firat University, Elazig, Turkey.

Background/aim: Ulnar compressive neuropathy is the second most common nerve compression in the upper extremity. Although numerous operative procedures have been defined for the treatment of cubital tunnel syndrome (CuTS), the best operative intervention remains controversial. The aim of this study is to discuss the efficacy of a modified simple decompression (MSD) of the ulnar nerve in the treatment of CuTS. Read More

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August 2018
2 Reads

Mandating nerve biopsy: A step towards personalizing therapy in pure neuritic leprosy.

J Peripher Nerv Syst 2018 Sep 27;23(3):190-196. Epub 2018 Aug 27.

Department of Neurology, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, India.

Pure neuritic leprosy (PNL) accounts for 5% to 10% of leprosy patients who usually present with asymmetrical neuropathy in the absence of lepra bacilli on slit-skin smears. However, nerve biopsies in PNL lack appropriate categorization in current immunologic terms. We aimed to classify nerve biopsies according to the immune spectrum of leprosy and assess the role of histologic classification of nerve biopsies in treating PNL. Read More

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September 2018
2 Reads

Delayed presentation of bilateral central hip protrusio acetabuli: evidence-based management.

BMJ Case Rep 2018 Aug 1;2018. Epub 2018 Aug 1.

Zografos, Athens, Greece.

This is a case of a previously healthy 51-year-old man who sustained bilateral central hip dislocations following a sudden presentation of epileptic seizures. The patient was initially treated conservatively for a period of 9 months. On presentation, he had gross disability due to stiffness in both hips and left peroneal nerve paresis. Read More

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August 2018
3 Reads

Differential Morphological and Biochemical Recovery from Chemotherapy-Induced Peripheral Neuropathy Following Paclitaxel, Ixabepilone, or Eribulin Treatment in Mouse Sciatic Nerves.

Neurotox Res 2018 Oct 26;34(3):677-692. Epub 2018 Jul 26.

Neuroscience Research Institute, University of California Santa Barbara, Santa Barbara, CA, 93106, USA.

The reversibility of chemotherapy-induced peripheral neuropathy (CIPN), a disabling and potentially permanent side effect of microtubule-targeting agents (MTAs), is becoming an increasingly important issue as treatment outcomes improve. The molecular mechanisms regulating the variability in time to onset, severity, and time to recovery from CIPN between the common MTAs paclitaxel and eribulin are unknown. Previously (Benbow et al. Read More

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October 2018
11 Reads

Femoral neuropathy following a psoas hitch vesicopexy.

BMJ Case Rep 2018 Jul 25;2018. Epub 2018 Jul 25.

Department of Anaesthesiology, erasmusMC, Rotterdam, The Netherlands.

A 68-year-old man classified as III on the American Society of Anaesthesiologists (ASA) physical status classification system, with a high-grade papillary urothelial cell carcinoma of the left distal ureter, underwent open retroperitoneal distal ureterectomy followed by a ureteroneocystostomy with a vesico-psoas hitch. Postoperatively, the patient complained of left proximal lower limb weakness, severe pain and hypaesthesia of the ventral left thigh suggestive of femoral neuropathy. After excluding common causes for postsurgical pain, a surgical re-exploration was eventually performed during which the sutures used in the vesicopexy were removed, resulting in almost complete resolution of the symptoms. Read More

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July 2018
7 Reads

A Novel Diagnostic and Prognostic Tool for Simple Decompression of Ulnar Nerve in Cubital Tunnel Syndrome.

World Neurosurg 2018 Oct 23;118:e964-e973. Epub 2018 Jul 23.

Division of Neurosurgery, University of Messina, A.O.U. Policlinico "G. Martino", Messina, Italy.

Background: Surgical decompression of the ulnar nerve (UN) is effective for treating cubital tunnel syndrome (CubTS). Nevertheless, the outcome is not always satisfying. Different surgical, clinical, and imaging findings have been claimed as outcome predictors, but there is no consensus in the literature. Read More

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October 2018
5 Reads

Trehalose prevents sciatic nerve damage to and apoptosis of Schwann cells of streptozotocin-induced diabetic C57BL/6J mice.

Biomed Pharmacother 2018 Sep 19;105:907-914. Epub 2018 Jun 19.

Department of Neurology, The Second Affiliated Hospital of Chongqing Medical University, 400010, China. Electronic address:

Type 1 diabetes (T1DM) affects approximately 1 in 500 children. Diabetic peripheral neuropathy (DPN) is the most common form of peripheral neuropathy in diabetes and is a significant risk factor for serious pathological change. It is difficult and costly to treat DPN and although there have been several pivotal trials. Read More

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September 2018
7 Reads

Extra-haematological manifestations related to human parvovirus B19 infection: retrospective study in 25 adults.

BMC Infect Dis 2018 Jul 4;18(1):302. Epub 2018 Jul 4.

Service de Médecine Interne, Centre de Référence Maladies Systémiques Autoimmunes Rares d'Ile de France, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris (AP-HP), Université Paris Descartes, Paris, France.

Background: To describe extra-haematological manifestations associated with human parvovirus B19 (HPV-B19) infection.

Methods: We conducted a nationwide multicentre study to retrospectively describe the characteristics and outcome of extra-haematological manifestations in French adults.

Results: Data from 25 patients followed from 2001 to 2016 were analysed. Read More

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July 2018
23 Reads

Lazarević-Lasègue sign.

Arq Neuropsiquiatr 2018 Jun;76(6):421-423

Neuroscience Research, Eli Lilly and Company, Indianapolis, USA.

Charles Lasègue is reputed to have described the test/sign bearing his name, but he never wrote about it and misinterpreted its mechanism. The purpose of this note is to highlight the work of the Serbian, Laza Lazarević, who was first to present the original report of this seminal sign in sciatica and provide its appropriate pathophysiological interpretation. Read More

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June 2018
3 Reads

Imaging Features of Varicella Zoster Virus Cranial Multiple Mononeuropathies.

Eur Neurol 2018 3;79(5-6):315-316. Epub 2018 Jul 3.

UOC Neurology, Fondazione Policlinico Universitario Agostino Gemelli, Institute of Neurology, Catholic University of Sacred Heart, Rome, Italy.

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July 2018
2 Reads
1.362 Impact Factor

Brachial plexus injury after shoulder dislocation: a literature review.

Neurosurg Rev 2018 Jun 30. Epub 2018 Jun 30.

Department of Traumatology, Clinical Department of Traumatology and Hand Surgery, Wroclaw Medical University, ul. Borowska 213, 50-556, Wroclaw, Poland.

Brachial plexus injuries are among the rarest but at the same time the most severe complications of shoulder dislocation. The symptoms range from transient weakening or tingling sensation of the upper limb to total permanent paralysis of the limb associated with chronic pain and disability. Conflicting opinions exist as to whether these injuries should be treated operatively and if so when surgery should be performed. Read More

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June 2018
3 Reads

Ruptured renal artery in microscopic polyangiitis: a case report and literature review.

CEN Case Rep 2018 11 27;7(2):301-306. Epub 2018 Jun 27.

Department of Nephrology, Okubo Hospital, 2-44-1 Kabuki-cho, Shinjuku-ku, Tokyo, 160-8488, Japan.

Medium-vessel hemorrhage is a rare occurrence in ANCA-associated vasculitis, and has been previously described in only a few patients with microscopic polyangiitis. We report a case of renal hemorrhage in a patient with microscopic polyangiitis that was successfully managed by transcatheter arterial embolization of the active bleeding sites. The early clinical findings included necrotizing arteritis, as indicated by skin biopsy; rapidly progressive glomerulonephritis; mononeuritis multiplex; positive screening for myeloperoxidase-specific antineutrophil cytoplasmic antibody. Read More

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November 2018
1 Read

Femoral nerve paralysis complicating a post-traumatic iliopsoas haematoma.

BMJ Case Rep 2018 Jun 21;2018. Epub 2018 Jun 21.

Department Of Orthopedic Surgery, Tunis El Manar University, Faculty Of Medecine, Tunis, Tunisia.

Paralysis of the femoral nerve secondary to iliopsoas haematoma is a rare post-traumatic complication. Because of the large differential diagnosis, a high level of suspicion is required for its early recognition. Treatment modalities are controversial due to the rarity of this entity. Read More

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June 2018
2 Reads

The Impact of Obesity on Orthopedic Upper Extremity Surgery.

Orthop Clin North Am 2018 Jul;49(3):345-351

Department of Orthopaedic Surgery, Texas Tech University Health Sciences Center, Mail Stop 9436, 3601 4th Street, Lubbock, TX 79430, USA; UMC Health System, 602 Indiana Avenue, Lubbock, TX 79415, USA. Electronic address:

Obese patients have increased rates of upper extremity injury, carpal tunnel syndrome, and upper extremity osteoarthritis. Preoperative considerations include cardiovascular disease, pulmonary disease, and diabetes mellitus. Intraoperative and anesthetic considerations include specialized equipment, patient positioning, and the physiology of obese patients. Read More

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July 2018
2 Reads

Sciatica Caused by Venous Varix Compression of the Sciatic Nerve.

World Neurosurg 2018 Sep 19;117:242-245. Epub 2018 Jun 19.

Department of Neurosurgery, Medical University of South Carolina, Charleston, South Carolina, USA.

Background: The authors report the case of a 76-year-old woman presenting with leg pain, numbness, and weakness mimicking a lumbosacral radiculopathy.

Case Description: Initial lumbar spine magnetic resonance imaging demonstrated mild root compression, but lumbar decompression afforded only transient symptomatic relief. Postoperative magnetic resonance imaging of the lumbosacral plexus and sciatic nerve revealed a gluteal venous varix compressing the sciatic nerve just distal to the piriformis muscle. Read More

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September 2018
21 Reads

Tarsal tunnel syndrome caused by an uncommon ossicle of the talus: A case report.

Medicine (Baltimore) 2018 Jun;97(25):e11008

Department of Orthopaedic Surgery, Soonchunhyang University Hospital Cheonan, Suncheonhyang 6-gil, Dongam-gu, Cheonan.

Rationale: Tarsal tunnel syndrome (TTS) is a compressive neuropathy of the posterior tibial nerve or one of its branches within the tarsal tunnel that is often caused by a variety of space-occupying lesions, such as ganglia, lipomas, varicosities, neural tumors, trauma, or systemic disease. The os sustentaculi is a small accessory bone, bridged to the posterior aspect of the sustentaculum tali by fibrocartilage. To the best of our knowledge, this is a rare case of successful treatment of TTS caused by the os sustantaculi. Read More

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June 2018
4 Reads

Sonographic assessment of carpal tunnel syndrome in diabetic patients with and without polyneuropathy.

Medicine (Baltimore) 2018 Jun;97(24):e11104

College of Medicine, Prince Sattam bin Abdulaziz University, Al-kharj, Kingdom of Saudi Arabia.

The objective of this study is to determine whether the cross sectional area (CSA) measurement of the median nerve at the wrist differ between carpal tunnel syndrome (CTS) in diabetic patients with and without diabetic polyneuropathy (DPN).This study included 44 patients with type II diabete millitus (DM) with CTS, 32 patients with CTS and DPN, 46 patients with idiopathic CTS, and 42 healthy subjects. Ultrasonographic measurement of the CSA of the median nerve was made at the level of the wrist, together with nerve conduction studies. Read More

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June 2018
10 Reads

Eosinophilic Granulomatosis with Polyangiitis Manifested by Cholecystitis and Mononeuritis Multiplex: A Case Report.

Iran J Med Sci 2018 May;43(3):332-335

Resident in Internal Medicine, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.

Eosinophilic granulomatosis with polyangiitis formerly named "Churg-Strauss syndrome (CSS)" is a systemic disease with bronchial asthma, hypereosinophilia, and systemic vasculitis. We report a case of CSS with cholecystitis and mononeuritis multiplex. A 50-year-old woman with a history of sinusitis and bronchial asthma of 8 years' duration was referred with a complaint of left-hand deformity and difficulty in walking. Read More

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May 2018
2 Reads

The role of electrophysiological examination in the diagnosis of carpal tunnel syndrome: Analysis of 2516 patients.

Niger J Clin Pract 2018 Jun;21(6):731-734

Department of Orthopedic and Traumatology, Develi Hatice-Muammer Kocaturk State Hospital, Kayseri, Turkey.

Objective: The aim of the present study was to assess the correlation between patient history, physical examination, and electrophysiological method of assessment in patients with clinical suspicion of carpal tunnel syndrome (CTS).

Patients And Methods: Results of electrophysiological examinations performed from 2009 to 2016 on 3151 hands of 2516 patients who had symptoms that clinically suggested CTS were examined retrospectively. Patients were assessed in terms of age, gender, direction of nerve compression, and presence and degree of CTS as determined electrophysiologically. Read More

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Recurrence of Extranodal Natural Killer/T-cell Lymphoma Presenting as Tarsal Tunnel Syndrome.

Am J Orthop (Belle Mead NJ) 2018 May;47(5)

Department of Orthopaedic Surgery, Pennsylvania State University Milton S. Hershey Medical Center, Hershey, PA.

This case report is a rare form of lymphoma recurrence which presented as tarsal tunnel syndrome. The patient had been previously treated for the malignancy and was presumed to be in remission; however, standard radiology imaging protocols failed to include the distal extremities on these scans. The patient presented to the orthopedic clinic with tarsal tunnel symptoms and a mass in the tarsal tunnel. Read More

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May 2018
6 Reads

Avascular necrosis: a growing concern for the HIV population.

BMJ Case Rep 2018 Jun 6;2018. Epub 2018 Jun 6.

Department of Internal Medicine, University of Florida Health, Jacksonville, Florida, USA.

A 33-year-old woman with history of HIV presented with 4 months of gradually progressing right hip pain and was found to have avascular necrosis (AVN) of both femoral heads. She had no other risk factors for AVN including sickle cell disease, systemic lupus erythematosus, prolonged steroid used or trauma. She initially failed conservative management and ultimately had bilateral hip core decompressions. Read More

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June 2018
4 Reads

Ultrasound-guided perineural injection with dextrose for treatment of radial nerve palsy: A case report.

Medicine (Baltimore) 2018 Jun;97(23):e10978

Department of Physical Medicine and Rehabilitation, Tri-Service General Hospital, School of Medicine, National Defense Medical Center, Taipei, Taiwan, Republic of China.

Rationale: Perineural injection with dextrose could be a novel intervention for peripheral entrapment neuropathy. However, this intervention has not been reported for treating radial nerve palsy (RNP). Here, we present a case with RNP having outstanding improvement after 2 sessions of ultrasound-guided perineural injection with 5% dextrose (D5W). Read More

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June 2018
11 Reads

Management of AO type 12C humerus proximal metadiaphyseal fractures with minimally invasive plate osteosynthesis in geriatric patients.

Clin Interv Aging 2018 22;13:1003-1010. Epub 2018 May 22.

Orthopaedics and Traumatology Department, Adana Numune Training and Research Hospital, Adana, Turkey.

Background: To evaluate the treatment efficacy and complications of the lateral minimally invasive plate osteosynthesis (MIPO) method in geriatric patients with a humerus diaphyseal fracture with proximal extension.

Patients And Methods: The study included a total of 21 patients (18 females, 3 males; mean age 74±6.3 years, range 65-89 years) who underwent surgery with the lateral MIPO technique for a humerus diaphyseal fracture with proximal extension during the period January 2011 to December 2016. Read More

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September 2018
24 Reads

Carpal tunnel syndrome treatment with palmitoylethanolamide: neurophysiology and ultrasound show small changes in the median nerve.

Rheumatol Int 2018 07 29;38(7):1307-1309. Epub 2018 May 29.

IRCCS Fondazione Don Carlo Gnocchi, Piazzale Morandi 6, 20121, Milan, Italy.

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July 2018
2 Reads

A Pulsed Electrical Joint Stimulator for the Treatment of Osteoarthritis of the Hand and Wrist.

Orthopedics 2018 Jul 30;41(4):e550-e556. Epub 2018 May 30.

The hand is commonly affected by osteoarthritis (OA). The development and progression of OA are believed to involve inflammation, even in the early stages of the disease. Inflammatory and proinflammatory cytokines have also been shown to be elevated in the flexor tenosynovium of idiopathic carpal tunnel syndrome (CTS). Read More

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July 2018
1 Read