20,866 results match your criteria Mononeuritis Multiplex


Mechanical properties of the sciatic nerve following combined transplantation of analytically extracted acellular allogeneic nerve and adipose-derived mesenchymal stem cells.

Acta Cir Bras 2020 5;35(4):e202000405. Epub 2020 Jun 5.

PhD, Biomechanics, Department of Orthopaedics, China-Japan Union Hospital, Jilin University, China. Technical procedures, analysis of data.

Purpose: To investigate the effects of Chemically Extracted Acellular Nerves (CEANs) when combined with Adipose-Derived mesenchymal Stem Cell (ADSC) transplantation on the repair of sciatic nerve defects in rabbits.

Methods: A total of 71 six-month-old Japanese rabbit were used in this study. Twenty rabbits served as sciatic nerve donors, while the other 51 rabbits were randomly divided into Autologous Nerve Transplantation Group (ANT, n=17), CEAN group (n=17) and CEAN-ADSCs group (n=17). Read More

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http://dx.doi.org/10.1590/s0102-865020200040000005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292625PMC

Endoscopic Carpal Tunnel Release: Indications, Technique, and Outcomes.

Orthop Clin North Am 2020 Jul;51(3):361-368

The Hand Center of San Antonio, 21 Spurs Lane # 310, San Antonio, TX 78240, USA. Electronic address:

Carpal tunnel is the most common peripheral compressive neuropathy. Nonoperative management may provide temporary alleviation of symptoms, but in most cases surgical decompression is warranted. There are a multitude of approaches ranging from open release under general anesthesia to wide awake in-office endoscopic carpal tunnel release. Read More

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http://dx.doi.org/10.1016/j.ocl.2020.02.001DOI Listing

Rheumatologic Disorders and the Nervous System.

Continuum (Minneap Minn) 2020 06;26(3):591-610

Purpose: This article describes the neurologic manifestations of systemic autoimmune diseases.

Recent Findings: Systemic autoimmune diseases can be associated with a wide spectrum of neurologic comorbidities involving the central and peripheral nervous systems. Systemic lupus erythematosus (SLE) can be associated with a number of manifestations predominantly affecting the central nervous system (CNS), whereas peripheral neuropathy is less common. Read More

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http://dx.doi.org/10.1212/CON.0000000000000856DOI Listing

Radial neuropathy caused by intraneural leiomyoma: A case report.

Medicine (Baltimore) 2020 May;99(22):e20196

Department of Physical and Rehabilitation Medicine.

Introduction: Leiomyoma of peripheral nerve is a rare condition characterized by neuropathy of affected nerve. We herein report a rare presentation of leiomyoma of radial nerve which presented with wrist drop.

Patient Concerns: A 37-year-old man visited our clinic with a history of sudden onset weakness of the wrist dorsiflexion/finger extension of the right side. Read More

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http://dx.doi.org/10.1097/MD.0000000000020196DOI Listing

Observational study on effectiveness and safety of integrative Korean medicine treatment for inpatients with sciatica due to lumbar intervertebral disc herniation.

Medicine (Baltimore) 2020 May;99(21):e20083

Jaseng Spine and Joint Research Institute, Jaseng Medical Foundation.

We developed a protocol for a prospective registry to prove the effectiveness and safety of integrative Korean medicine treatment for inpatients with sciatica due to lumbar intervertebral disc herniation. We plan on recruiting 1000 inpatients receiving integrative Korean medicine treatment for lumbar intervertebral disc herniation at four spine specialized Korean medical hospitals. Patients enrolled in the registry will be evaluated at the time of hospitalization, 2 weeks after hospitalization, at discharge, and 6 months after hospitalization on predefined outcome variables such as intensity of back and leg pain, Oswestry Disability Index, quality of life, Patient Global Impression of Change, and adverse effects. Read More

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http://dx.doi.org/10.1097/MD.0000000000020083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249894PMC

[Mononeuritis Multiplex: A Diagnostic Challenge].

Praxis (Bern 1994) 2020 ;109(7):509-512

Medizinische Klinik, Zuger Kantonsspital, Baar.

Mononeuritis Multiplex: A Diagnostic Challenge Eosinophilic granulomatosis with polyangiitis (EGPA, formerly Churg-Strauss syndrome) is a multifaceted disease. Due to the variability in vascular and organ involvement, EPGA can manifest itself very differently. We report a case of a 60-year-old patient with a known bronchial asthma, pansinusitis and newly blood eosinophilia with a rapid-onset mononeuritis multiplex. Read More

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http://dx.doi.org/10.1024/1661-8157/a003445DOI Listing
January 2020

Risk of carpal tunnel syndrome after parathyroidectomy in patients with end-stage renal disease: A population-based cohort study in Taiwan.

Medicine (Baltimore) 2020 May;99(20):e20313

Graduate Institute of Biomedical Sciences.

Carpal tunnel syndrome (CTS) is the most common mononeuropathy in clinical practice. Some patients with end-stage renal disease (ESRD) often associate with tertiary hyperparathyroidism, and ultimately need parathyroidectomy (PTX). However, no studies have definitively demonstrated an effect of PTX on ESRD patients' quality of life. Read More

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http://dx.doi.org/10.1097/MD.0000000000020313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7254828PMC

Carpal tunnel syndrome in acromegaly is also related to median nerve oedema.

Authors:
Philippe Chanson

BMJ 2020 04 30;369:m1701. Epub 2020 Apr 30.

Service d'Endocrinologie et des Maladies de la Reproduction, Hôpital Bicêtre, 94275 Le Kremlin-Bicêtre, France.

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http://dx.doi.org/10.1136/bmj.m1701DOI Listing

Deep gluteal syndrome as a cause of posterior hip pain and sciatica-like pain.

Bone Joint J 2020 May;102-B(5):556-567

Department of Orthopedic Surgery, Seoul National University Bundang Hospital, Department of Orthopedic Surgery, Seoul National University College of Medicine Seongnam, South Korea.

Deep gluteal syndrome is an increasingly recognized disease entity, caused by compression of the sciatic or pudendal nerve due to non-discogenic pelvic lesions. It includes the piriformis syndrome, the gemelli-obturator internus syndrome, the ischiofemoral impingement syndrome, and the proximal hamstring syndrome. The concept of the deep gluteal syndrome extends our understanding of posterior hip pain due to nerve entrapment beyond the traditional model of the piriformis syndrome. Read More

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http://dx.doi.org/10.1302/0301-620X.102B5.BJJ-2019-1212.R1DOI Listing

Vasculitis and the peripheral nervous system.

Authors:
Lionel Ginsberg

Rheumatology (Oxford) 2020 May;59(Supplement_3):iii55-iii59

Department of Neurology, Royal Free Hospital, London, UK.

Peripheral neuropathy is a common feature of systemic vasculitis and can also occur when vessel wall inflammation is confined to the vasa nervorum, as a tissue-specific condition-non-systemic vasculitic neuropathy (NSVN). Typically, the clinical picture in both systemic and non-systemic cases is of a lower limb predominant, distal, asymmetric or multifocal neuropathy, which is painful and subacute in onset. For NSVN, nerve biopsy is required to make the diagnosis, and nerve biopsy also has a role when vasculitic neuropathy is suspected and a systemic process has not yet declared itself. Read More

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http://dx.doi.org/10.1093/rheumatology/keaa075DOI Listing

Eosinophilic granulomatosis with polyangiitis: understanding the disease and its management.

Rheumatology (Oxford) 2020 May;59(Supplement_3):iii84-iii94

Department of Biomedical Experimental and Clinical Sciences 'Mario Serio', University of Firenze, Florence, Italy.

Eosinophilic granulomatosis with polyangiitis is characterized by asthma, blood and tissue eosinophilia and small-vessel vasculitis. The clinical presentation is variable, but two main clinic-pathologic subsets can be distinguished: one hallmarked by positive ANCA and predominant 'vasculitic' manifestations (e.g. Read More

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http://dx.doi.org/10.1093/rheumatology/kez570DOI Listing

Microscopic polyangiitis: Clinical characteristics and long-term outcomes of 378 patients from the French Vasculitis Study Group Registry.

J Autoimmun 2020 Apr 24:102467. Epub 2020 Apr 24.

Department of Internal Medicine, National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, APHP, Université Paris Descartes, Paris, France. Electronic address:

Objective: To describe characteristics and long-term outcomes of patients with microscopic polyangiitis (MPA), an antineutrophil cytoplasm antibody (ANCA)-associated small-vessel necrotizing vasculitis.

Methods: MPA patients from the French Vasculitis Study Group Registry satisfying the European Medicines Agency algorithm were analyzed retrospectively. Characteristics at diagnosis, treatments, relapses and deaths were analyzed to identify factors predictive of death or relapse. Read More

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http://dx.doi.org/10.1016/j.jaut.2020.102467DOI Listing
April 2020
8.410 Impact Factor

Carpal tunnel sonography.

J Ultrasound 2020 Apr 22. Epub 2020 Apr 22.

Radiology Department, San Donato Hospital Group, Istituto Clinico Città di Brescia, Via Bartolomeo Gualla 15, 25128, Brescia, Italy.

Carpal tunnel syndrome (CTS) is the most frequent entrapment neuropathy of peripheral nerves, with an incidence of 1-3 patients in 1000. CTS typically occurs between 45 and 60 years of age, and it is more frequent in women than in men. The main cause of CTS is chronic compression of the median nerve and ischemic suffering secondary to increased pressure in the carpal tunnel. Read More

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http://dx.doi.org/10.1007/s40477-020-00460-zDOI Listing

The functional effect of 3D-printing individualized orthosis for patients with peripheral nerve injuries: Three case reports.

Medicine (Baltimore) 2020 Apr;99(16):e19791

Department of Physical Medicine and Rehabilitation, Catholic Kwandong University International St Mary's Hospital, Incheon.

Rationale: In the medical field, the use of 3-dimensional (3D) printing is increasing explosively and it is especially widespread in the clinical application of fabricating orthosis. Advantages of 3D-printed orthosis compared to conventional ones include its lower cost, easier modification, and faster fabrication. The 3D-printing technique makes it possible for physicians to easily create individual-tailored products. Read More

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http://dx.doi.org/10.1097/MD.0000000000019791DOI Listing

Appropriately Selected Nerve in Suspected Leprous Neuropathy Yields High Positive Results for DNA by Polymerase Chain Reaction Method.

Am J Trop Med Hyg 2020 Apr 13. Epub 2020 Apr 13.

Department of Neurology, National Institute of Mental Health and Neurosciences, Bangalore, India.

Identification of DNA by polymerase chain reaction (PCR) is a reliable and an affordable method to confirm leprosy. DNA from 87 nerve samples (56 from paraffin blocks and 26 fresh samples) was extracted. DNA was amplified by PCR from 80/87 (92%) specimens. Read More

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http://dx.doi.org/10.4269/ajtmh.19-0746DOI Listing
April 2020
2.699 Impact Factor

Mid-palm recording technique, a new electrodiagnostic approach in Martin-Gruber anastomosis.

Clin Neurophysiol Pract 2020 20;5:79-82. Epub 2020 Mar 20.

Division of Neurology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Introduction: Median and ulnar motor nerve conduction study recording from median-innervated 2nd lumbrical and ulnar-innervated 1st palmar and 2nd dorsal interossei is designated in electrodiagnostic evaluation of carpal tunnel syndrome. In this technique, both responses are recorded by the same surface recording electrode placing over their shared motor point in mid-palm. To the best of our knowledge, this technique has never been utilized in demonstration of Martin-Gruber anastomosis. Read More

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http://dx.doi.org/10.1016/j.cnp.2020.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138930PMC

Eosinophilic granulomatosis with polyangiitis presenting with myositis: case based review.

Rheumatol Int 2020 Jul 8;40(7):1163-1170. Epub 2020 Apr 8.

Division of Rheumatology, University of Toronto, Toronto, ON, Canada.

Eosinophilic granulomatosis with polyangitis (EGPA) is a systemic necrotizing small-vessel vasculitis that presents heterogeneously as a multi-organ disease. EGPA evolves through three phases: (1) prodromic phase with asthma, atopy and sinusitis, (2) eosinophilic phase characterized by peripheral eosinophilia and eosinophilic infiltration without necrosis, and (3) vasculitic phase involving organ damage. EGPA often presents with asthma, mononeuritis multiplex, lung infiltrates, sinusitis and constitutional symptoms. Read More

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http://dx.doi.org/10.1007/s00296-020-04567-8DOI Listing

Multiple jeopardy: Diagnostic and therapeutic challenges in vasculitic flare.

Int J Rheum Dis 2020 May 7;23(5):697-701. Epub 2020 Apr 7.

Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS), Lucknow, India.

A 57-year old gentleman had presented a year back with inflammatory oligoarthritis and vasculitic neuropathy, diagnosed as unclassifiable vasculitis, initiated on oral corticosteroids and intravenous cyclophosphamide (monthly X 6). His disease stabilized and he had been maintained on azathioprine, which had to be stopped due to acute pancreatitis with subsequent pseudocyst formation, requiring percutaneous drainage suspecting infection. Within a week of pseudocyst drainage, he developed sudden onset pain in left upper limb, with absent left upper limb pulses, loss of motor function of left hand, myocardial ischemia, and extensive thrombosis of the left upper limb arteries. Read More

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http://dx.doi.org/10.1111/1756-185X.13836DOI Listing
May 2020
1.771 Impact Factor

[Endoscopic release of the ulnar tunnel. Technique and clinical-functional outcomes].

Acta Ortop Mex 2019 Sep-Oct;33(5):303-307

Ortopedia y Traumatología. Hospital Regional de Alta Especialidad del Bajío. México.

Introduction: The ulnar tunnel syndrome is the second compressive neuropathy, followed by the carpal tunnel, making it a frequent reference in hand surgery. There are few published studies about endoscopic technique.

Material And Methods: We studied 26 patients with ulnar tunnel syndrome diagnosis, were operated by endoscopic release of the ulnar tunnel. Read More

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Pathological, ultrasonographic, and electrophysiological characterization of clinically diagnosed cases of pure neuritic leprosy.

J Peripher Nerv Syst 2020 Jun 23;25(2):191-203. Epub 2020 Apr 23.

Department of Neurology, KGMU, Lucknow, India.

A subset of neuritic form of leprosy, called pure neuritic leprosy (PNL), seen in a minority of leprosy patients, is characterized by peripheral neuropathy without skin lesions and an absence of acid-fast bacilli on skin smears. Patients with PNL are often started on drug therapy without confirmation of diagnosis. We, therefore, did a prospective study of clinically diagnosed PNL patients with correlation of ultrasonographic and biopsy findings. Read More

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http://dx.doi.org/10.1111/jns.12372DOI Listing
June 2020
2.758 Impact Factor

Syndrome of inappropriate antidiuretic hormone associated with eosinophilic granulomatosis and polyangiitis.

BMJ Case Rep 2020 Mar 24;13(3). Epub 2020 Mar 24.

Intensive Care and Neurointensive Care, Sparrow Hospital, Lansing, Michigan, USA.

A 62-year-old man presented with classic signs and symptoms of eosinophilic granulomatosis and polyangiitis (EGPA, also known as Churg-Strauss syndrome)-mononeuritis multiplex, palpable purpura, hypereosinophilia, positive P-ANCA (perinuclear anti-neutrophil cytoplasmic antibodies) developed diffuse alveolar haemorrhage. The patient had longstanding mild hyponatraemia, but developed moderate and symptomatic hyponatraemia characteristic of the syndrome of inappropriate antidiuretic hormone. The patient's serum sodium returned to his baseline- mildly hyponatraemic, after initiation of treatment targeted towards EGPA. Read More

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http://dx.doi.org/10.1136/bcr-2019-231249DOI Listing

[Serum biomarkers in acute low back pain and sciatica].

Orv Hetil 2020 Mar;161(13):483-490

Általános Orvostudományi Kar, Neurológiai Klinika, Semmelweis Egyetem Budapest, Balassa u. 6., 1083.

Inflammation contributes to the pathogenesis of low back pain and sciatica. Growing evidence suggests that elevated levels of some inflammatory biomarkers are associated with these conditions. Much of the research evaluating the association between pro- and anti-inflammatory cytokines, chemokines, other regulatory molecules, and low back pain and sciatica, focused on patients with chronic low back pain, while fewer studies addressed the issue of detectable biomarkers in the acute phase. Read More

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http://dx.doi.org/10.1556/650.2020.31665DOI Listing

Superficial peroneal nerve compression due to peroneus brevis muscle herniation.

Authors:
Michele Foresti

J Radiol Case Rep 2019 Nov 30;13(11):10-17. Epub 2019 Nov 30.

Radiology Unit, Department of Diagnostic Imaging and Laboratory Medicine, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.

Muscle hernias of the extremities most commonly occur in the leg, between the knee and ankle. Symptomatic muscle hernias in the leg are rare cause of chronic leg pain and neuropathy, and not routinely encountered in surgical practice. Although this condition is especially an esthetic problem, with palpable subcutaneous soft tissue mass, it can lead to spontaneous pain, cramp, local tenderness or potentially neuropathic symptoms. Read More

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http://dx.doi.org/10.3941/jrcr.v13i11.3757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060001PMC
November 2019

Decision Making for Treatment of Persistent Sciatica.

N Engl J Med 2020 03;382(12):1161-1162

From the Department of Orthopedic Surgery, Brigham and Women's Hospital, and Harvard Medical School, Boston.

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http://dx.doi.org/10.1056/NEJMe2000711DOI Listing

Surgery versus Conservative Care for Persistent Sciatica Lasting 4 to 12 Months.

N Engl J Med 2020 03;382(12):1093-1102

From the Department of Surgery (C.S.B., P.R., D.T., S.I.B., K.R.G., F.S., A.G., J.C.U.) and Occupational Health and Safety (R.R.), London Health Sciences Centre, Schulich School of Medicine and Dentistry, Western University (C.S.B., P.R., D.T., S.I.B., K.R.G., F.S., A.G.), Lawson Health Research Institute (C.S.B., P.R., J.C.U.), Regional Rehabilitation and Spinal Cord Injury Outpatients, Parkwood Institute (K.S.), and the Departments of Physical Medicine and Rehabilitation (T.M.) and Anesthesia and Perioperative Medicine (J.W.), St. Joseph's Hospital - all in London, ON, Canada.

Background: The treatment of chronic sciatica caused by herniation of a lumbar disk has not been well studied in comparison with acute disk herniation. Data are needed on whether diskectomy or a conservative approach is better for sciatica that has persisted for several months.

Methods: In a single-center trial, we randomly assigned patients with sciatica that had lasted for 4 to 12 months and lumbar disk herniation at the L4-L5 or L5-S1 level in a 1:1 ratio to undergo microdiskectomy or to receive 6 months of standardized nonoperative care followed by surgery if needed. Read More

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http://dx.doi.org/10.1056/NEJMoa1912658DOI Listing

Infraspinatus muscle palsy involving suprascapular nerve, brachial plexus or cervical roots related to inflammatory or mechanical causes: Experience of 114 cases.

Neurophysiol Clin 2020 Apr 5;50(2):103-111. Epub 2020 Mar 5.

INSERM UMR-S 1153, Service de Rééducation et de Réadaptation de l'Appareil Locomoteur et des Pathologies du Rachis, PRES Sorbonne Paris Cité, ECaMO team, Institut Fédératif de Recherche sur le Handicap, Hôpital Cochin, Université Paris Descartes, AP-HP, Paris, France.

Objectives: To report a large series of neurogenic infraspinatus muscle (ISM) palsy, in order to improve knowledge of diagnosis, diverse etiologies and care management.

Methods: Clinical and electrodiagnostic (EDX) data for 114 cases of ISM palsy were collected over a 21-year period. Cases were attributed to 4 clinical conditions: (1) isolated suprascapular nerve mononeuropathy (n=48), (2) multiple mononeuropathies (n=33), (3) plexus lesions (n=17), and (4) cervical radiculopathy (n=16). Read More

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http://dx.doi.org/10.1016/j.neucli.2020.02.002DOI Listing

[Gluteal compartment syndrome after immobilization following opioid abuse].

Unfallchirurg 2020 Jun;123(6):496-500

Klinik für Allgemeine, Unfall- und Wiederherstellungschirurgie, Klinikum der Universität München, Campus Innenstadt und Großhadern, Marchioninistraße 17, 81377, München, Deutschland.

This article reports the case of a 42-year-old male patient, who sustained a gluteal compartment syndrome after drug-induced immobilization with subsequent rhabdomyolysis and sciatic nerve palsy. Unlike compartment syndrome of the forearm or lower leg, this is a rare condition. After immediate surgical decompression and installation of negative pressure wound treatment, hemofiltration in acute renal failure could be averted using forced diuresis. Read More

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http://dx.doi.org/10.1007/s00113-020-00792-9DOI Listing

Neuromuscular manifestations of lead poisoning in opium and herbal users in Iran.

Rev Neurol (Paris) 2020 Mar 2. Epub 2020 Mar 2.

Faculty of Medicine, Tehran University of Medical Sciences, Shariati Hospital, North Kargar Street, Tehran, Iran; CNRS (UMR 7339), centre de résonance magnétique biologique et médicale, faculté de médecine, Aix Marseille University, 27, boulevard J. Moulin, 13005 Marseille, France. Electronic address:

Opium sale is prohibited in Iran, and sellers mix it with lead to increase the weight. Herein, we describe neuromuscular findings in nine patients who developed lead poisoning due to opium/drug consumption. The mean age of patients was 53±3. Read More

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http://dx.doi.org/10.1016/j.neurol.2019.12.004DOI Listing

Microscopic polyangiitis: an incidental finding in a patient with stroke.

J Community Hosp Intern Med Perspect 2020 10;10(1):50-54. Epub 2020 Feb 10.

Internal Medicine, Liaquat National Hospital and Medical College, Karachi, Pakistan.

Microscopic polyangiitis (MPA) is a primary systemic vasculitis characterized by inflammation of small-sized vessels associated with the presence of anti-neutrophilic cytoplasmic antibodies. We report a case of a 39-year-old female diagnosed with microscopic polyangiitis as an incidental finding who presented with signs and symptoms of a stroke at a young age. Usually, it presents with fever, malaise, skin rash, weight loss, mononeuritis multiplex, and arthralgia/myalgia. Read More

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http://dx.doi.org/10.1080/20009666.2020.1718479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034484PMC
February 2020

[Design and application of prevention baffle for foot drop in suspension bed].

Zhonghua Shao Shang Za Zhi 2020 Feb;36(2):131-132

Department of Gynaecology, the First Hospital of Jilin University, Changchun 130021, China.

Suspension bed are often used to treat and nurse the wounds of burn patients in clinic. Because of the suspension force, the patients' activities are limited, and they stay in bed for a long time, which is very easy to cause foot drop, affecting the recovery of the patients. Aiming at this problem, we designed and made a foot drop prevention baffle made of stainless steel, which could withstand the buoyancy of the suspension bed, adjust the feet forwardly and backwardly, to the left and right according to the height of the patients and the distance of the feet to be separated, and keep the foot in a positive and external rotation position according to the comfort of the patients, which achieved good results in clinical application. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1009-2587.2020.02.009DOI Listing
February 2020

Differential gene expression changes in the dorsal root versus trigeminal ganglia following peripheral nerve injury in rats.

Eur J Pain 2020 May 13;24(5):967-982. Epub 2020 Mar 13.

Department of Diagnostic Sciences, Rutgers School of Dental Medicine, Rutgers, The State University of New Jersey, Newark, NJ, USA.

Background: The dorsal root (DRG) and trigeminal (TG) ganglia contain cell bodies of sensory neurons of spinal and trigeminal systems, respectively. They are homologs of each other; however, differences in how the two systems respond to injury exist. Trigeminal nerve injuries rarely result in chronic neuropathic pain (NP). Read More

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http://dx.doi.org/10.1002/ejp.1546DOI Listing

Carpal Tunnel Release without a Tourniquet: A Systematic Review and Meta-Analysis.

Plast Reconstr Surg 2020 03;145(3):737-744

Hamilton and Toronto, Ontario, Canada From the Michael G. DeGroote School of Medicine, the Department of Health Research Methods, Evidence and Impact, and the Division of Plastic Surgery, Department of Surgery, McMaster University; and the Faculty of Health, York University.

Background: Open carpal tunnel release is commonly performed with the use of a tourniquet. The combination of local anesthetic and epinephrine with a pneumatic tourniquet helps provide clear visualization during decompression of the median nerve. There has been a rapid expansion of literature challenging the use of tourniquets in open carpal tunnel release. Read More

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http://dx.doi.org/10.1097/PRS.0000000000006549DOI Listing

Clinical associations of renal involvement in ANCA-associated vasculitis.

Autoimmun Rev 2020 Apr 15;19(4):102495. Epub 2020 Feb 15.

Norwich Medical School, University of East Anglia, Norwich, United Kingdom.

Objective: Renal involvement in anti-neutrophil cytoplasm antibody (ANCA)-associated vasculitis is associated with significant morbidity and higher mortality rates. This study examined clinical manifestations associated with renal involvement in ANCA-associated vasculitis within a large, international cross-sectional cohort.

Methods: Univariate and multivariate analyses were performed to identify clinical factors associated with renal disease, which was defined as i) a serum-creatinine >30% above normal and a fall in creatinine-clearance >25%; or ii) haematuria attributable to active vasculitis. Read More

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http://dx.doi.org/10.1016/j.autrev.2020.102495DOI Listing

Superb microvascular imaging (SMI) in the evaluation of musculoskeletal disorders: a systematic review.

Radiol Med 2020 May 4;125(5):481-490. Epub 2020 Feb 4.

Dipartimento di Scienze Biomediche per la Salute, Università degli Studi di Milano, Via Luigi Mangiagalli 31, 20133, Milano, Italy.

Objectives: To systematically review the current literature concerning the role of superb microvascular imaging (SMI), a novel Doppler technique that enables detection of fine vessels and slow blood flow, in the evaluation of musculoskeletal disorders.

Methods: An online search of the literature was conducted for the period 2013 to April 2019 and included original articles written in English language. A data analysis was performed at the end of the literature search. Read More

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http://dx.doi.org/10.1007/s11547-020-01141-xDOI Listing

[The piriformis syndrome-a special indication for botulinum toxin].

Authors:
W Hermann

Nervenarzt 2020 Feb;91(2):99-106

SRO AG Langenthal, St. Urbanstraße 67, 4900, Langenthal, Deutschland.

The piriformis syndrome (PiS) is a possible cause of gluteal pain radiating into the legs. From a pathophysiological anatomical point of view a division into primary and secondary PiS is made. A primary PiS is based on variants of the course of the sciatic nerve with respect to the piriformis muscle. Read More

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http://dx.doi.org/10.1007/s00115-020-00866-4DOI Listing
February 2020

Reply.

Authors:
Nigel Ashworth

Muscle Nerve 2020 04 7;61(4):E31-E32. Epub 2020 Feb 7.

Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1002/mus.26814DOI Listing

Laterality of the ulnar neuropathy at the elbow.

Authors:
Simon Podnar

Muscle Nerve 2020 04 4;61(4):E30-E31. Epub 2020 Feb 4.

Institute of Clinical Neurophysiology, Division of Neurology, University Medical Center Ljubljana, Ljubljana, Slovenia.

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http://dx.doi.org/10.1002/mus.26815DOI Listing

An Evaluation of Safety and Patient Outcomes for Hand Surgery following Prior Breast Cancer Treatment: Establishing New Recommendations in Lymphedema.

Plast Reconstr Surg 2020 Feb;145(2):459-467

Aurora, Colo. From the University of Colorado School of Medicine; and the Division of Plastic and Reconstructive Surgery, University of Colorado, Anschutz Medical Center.

Background: Injuries to the upper extremity lymphatic system from cancer may require measures to prevent secondary lymphedema. Guidelines were established relating to the use of tourniquet and elective hand and upper extremity surgery. However, reports in the setting of hand surgery have indicated that prior guidelines may not be protective to the patient. Read More

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http://dx.doi.org/10.1097/PRS.0000000000006438DOI Listing
February 2020

The Risk of Complications after Carpal Tunnel Release in Patients Taking Acetylsalicylic Acid as Platelet Inhibition: A Multicenter Propensity Score-Matched Study.

Plast Reconstr Surg 2020 Feb;145(2):360e-367e

Westerstede, Hannover, Rostock, and Oldenburg, Germany; and Groningen, The Netherlands From the Department of Trauma, Orthopedic, Plastic, Reconstructive, and Hand Surgery, Federal Armed Forces Hospital Westerstede; the Department of Plastic, Aesthetic, Hand, and Reconstructive Surgery, Hannover Medical School; the Department of Orthopedics, University Medicine Rostock; the Institute of Hand and Plastic Surgery Oldenburg; and the Department of Plastic Surgery, University Medical Centre Groningen, University of Groningen.

Background: Carpal tunnel release is one of the most common procedures in hand surgery. There is only scarce evidence regarding whether platelet inhibitors increase the risk of developing postoperative hemorrhage in carpal tunnel release.

Methods: This is a multicenter, propensity score-matched study including 635 carpal tunnel releases in 497 patients. Read More

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http://dx.doi.org/10.1097/PRS.0000000000006465DOI Listing
February 2020

Anatomical analysis of the pelvis to identify any predisposing anatomical factors for ischiofemoral space pathology: a retrospective study.

Br J Radiol 2020 Apr 29;93(1108):20190556. Epub 2020 Jan 29.

Dra. Roca Diagnóstico Médico. CEMEDI, Carrera del Sábado, 4, 50006, Zaragoza, Spain.

Objective: Anatomical analysis of the hips and pelvis was performed using MRI to evaluate morphological characteristics and associations between them. We identified correlations between the ischiofemoral space (IFS), quadratus femoris space (QFS), femoral version angle (FVA) and cervicodiaphyseal angle (CDA).

Methods: This study involved a retrospective search of a database of consecutive reports of adult hip MRI examinations carried out between January and September 2016. Read More

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http://dx.doi.org/10.1259/bjr.20190556DOI Listing

Quality measures in electrodiagnosis: Carpal tunnel syndrome-An AANEM Quality Measure Set.

Muscle Nerve 2020 04 3;61(4):460-465. Epub 2020 Feb 3.

Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, Massachusetts.

Carpal tunnel syndrome (CTS) is a common neuromuscular condition and a major cause of work-related disability. As healthcare in the United States transitions toward a value-based system from fee-for-service, quality measures assume importance in the evaluation of care provided. This report from the American Association of Neuromuscular & Electrodiagnostic Medicine Quality Improvement Committee provides an introduction to quality measures and outlines a quality measurement set for the electrodiagnosis of CTS. Read More

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http://dx.doi.org/10.1002/mus.26810DOI Listing

Patient Characteristics in Ulnar Nerve Compression at the Elbow at a Tertiary Referral Hospital and Predictive Factors for Outcomes of Simple Decompression versus Subcutaneous Transposition of the Ulnar Nerve.

Biomed Res Int 2019 19;2019:5302462. Epub 2019 Dec 19.

Division of Clinical Sciences, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.

Patient characteristics and predictive factors for outcomes were analysed in 202 cases undergoing simple decompression, primary subcutaneous transposition, or secondary subcutaneous transposition for ulnar nerve compression at the elbow at a tertiary referral hospital. Data from medical charts and a survey were evaluated. The mean patient age was 49 years with revision surgery cases being significantly younger. Read More

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http://dx.doi.org/10.1155/2019/5302462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948284PMC

Optimized Design of a Variable Viscosity Link for Robotic AFO.

Conf Proc IEEE Eng Med Biol Soc 2019 07;2019:6220-6223

Herein we present the development of a novel Ankle Foot Orthosis for gait support of people with foot-drop symptoms. The developed AFO uses an elastic link mechanism to brake the ankle joint during initial contact, thus mitigating foot-slap, and an integrated energy store-and-release mechanism to support toe lift in the swing phase, thus mitigating toe-drag. This paper presents improvements in the braking-holding power of the elastic link mechanism over its previous version, the torque-angle characteristics of the developed AFO with the renewed elastic link, and a pilot test with one person with foot-drop symptoms to verify the proposed functions of the developed AFO. Read More

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http://dx.doi.org/10.1109/EMBC.2019.8856773DOI Listing

Pilot Study of Cadence, a Novel Shoe for Patients with Foot Drop.

Conf Proc IEEE Eng Med Biol Soc 2019 07;2019:5291-5296

Foot Drop is a mobility disorder that limits ankle dorsiflexion, complicating the swing phase of gait and balance. It is a common result of a neurological injury or disease such as stroke, cerebral palsy or multiple sclerosis. Here we present Cadence, a low-cost assistive shoe designed to passively improve the biomechanics and rhythmicity of gait for people with foot drop. Read More

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http://dx.doi.org/10.1109/EMBC.2019.8857096DOI Listing

[Peroneal Nerve Palsy Management by Tibialis Posterior Muscle Transposition - Anatomical and Clinical Study].

Acta Chir Orthop Traumatol Cech 2019 ;86(6):419-422

Ústav anatomie Lékařské fakulty Univerzity Karlovy, Hradec Králové.

PURPOSE OF THE STUDY Transposition of tibialis posterior muscle ranks among the methods of dorsiflexion restoration in patients with peroneal nerve palsy. Even though this method is commonly used, anatomical variations are still encountered which make us modify the established procedures. The purpose of this study is to evaluate the functional outcomes of operated patients and based on the clinical experience to define by cadaver preparation the anatomical causes preventing the use of the standard transposition technique. Read More

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January 2020

Peroneal nerve palsy caused by a synovial cyst of the proximal tibiofibular joint: a report of two cases and review of the literature.

Pan Afr Med J 2019 29;34:115. Epub 2019 Oct 29.

Department of Trauma and Orthopaedics Surgery, Fattouma Bourguiba University Hospital, Monastir, Tunisia.

Synovial cyst of the proximal tibiofibular joint is a very rare condition, for which there is no consensus regarding treatment. Two macroscopic forms may be encountered: extraneural cysts and intraneural cysts. We present the cases of two patients who had synovial cysts of proximal tibiofibular joint that caused peroneal nerve palsy. Read More

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http://dx.doi.org/10.11604/pamj.2019.34.115.18339DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945372PMC
January 2020

Novel Neuropathic Pain Mechanisms Associated With Allergic Inflammation.

Front Neurol 2019 17;10:1337. Epub 2019 Dec 17.

Department of Neurology, Graduate School of Medical Sciences, Neurological Institute, Kyushu University, Fukuoka, Japan.

Allergic diseases are associated with central and peripheral nervous system diseases such as autism spectrum disorders and eosinophilic granulomatosis with polyangiitis, which frequently causes mononeuritis multiplex. Thus, it is possible that patients with an atopic constitution might develop multifocal inflammation in central and peripheral nervous system tissues. In a previous study in Japan, we reported a rare form of myelitis with persistent neuropathic pain (NeP) in patients with allergic disorders. Read More

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http://dx.doi.org/10.3389/fneur.2019.01337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928142PMC
December 2019

Association of Sleep and Hand Function in People With Carpal Tunnel Syndrome.

Am J Occup Ther 2019 Nov/Dec;73(6):7306205050p1-7306205050p7

Doris Pierce, PhD, OTR/L, FAOTA, is Endowed Chair in Occupational Therapy, Eastern Kentucky University, Richmond.

This study examined whether sleep quality is associated with hand function above and beyond what can be explained by the effect of pain and carpal tunnel syndrome (CTS) severity on hand function in clients with CTS. The sample included 53 adults ages 30-86 yr. The Manual Ability Measure-20, Pittsburgh Sleep Quality Index, visual analog scale for pain, and electromyography for CTS diagnosis and severity level were used to measure outcomes. Read More

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http://dx.doi.org/10.5014/ajot.2019.034157DOI Listing
January 2020

Postpartum femoral neuropathy: managing the next pregnancy.

BMJ Case Rep 2019 Dec 29;12(12). Epub 2019 Dec 29.

Obstetrics & Gynaecology, Rotunda Hospital, Dublin, Ireland.

A 34-year-old primiparous woman presented in spontaneous labour and had an unassisted vaginal birth of a 3.5 kg infant. Postnatally, the patient experienced lower limb weakness and was unable to mobilise unassisted. Read More

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http://dx.doi.org/10.1136/bcr-2019-232967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936406PMC
December 2019

Neuromuscular ultrasound in clinical practice: A review.

Clin Neurophysiol Pract 2019 12;4:148-163. Epub 2019 Jul 12.

Department of Neurology/Neuromuscular Division, Duke University Hospital, DUMC 3403, Durham, NC 27710, USA.

Neuromuscular ultrasound (NMUS) is becoming a standard element in the evaluation of peripheral nerve and muscle disease. When obtained simultaneously to electrodiagnostic studies, it provides dynamic, structural information that can refine a diagnosis or identify a structural etiology. NMUS can improve patient care for those with mononeuropathies, polyneuropathy, motor neuron disease and muscle disorders. Read More

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http://dx.doi.org/10.1016/j.cnp.2019.04.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921231PMC