Search Our Scientific Publications & Authors

Anesth Analg 2018 Dec 11. Epub 2018 Dec 11.

From the Department of Anesthesia and Intensive Care, Military Teaching Hospital "Clermont Tonnerre", Brest, French.

Background: Wired electrocardiogram monitors are an important component of current perioperative monitoring. Wireless monitoring units could help reduce the number of cables attached to patients and thus improve anesthesia ergonomics and patient management. However, there is concern that electromagnetic interference generated by electrosurgical units may prevent effective wireless signals in the operating room. Read More

Curr Opin Anaesthesiol 2018 Dec 11. Epub 2018 Dec 11.

Department of Anesthesiology.

Purpose Of Review: The current review focuses on precise anesthesia for video-assisted thoracoscopic surgery (VATS) with the goal of enhanced recovery.

Recent Findings: VATS has become an established and widely used minimally invasive approach with broad implementation on a variety of thoracic operations. In the current environment of enhanced recovery protocols and cost containment, minimally invasive VATS operations suggest adoption of individualized tailored, precise anesthesia. Read More

Adv Physiol Educ 2019 Mar;43(1):34-41

NeuroV̇ASQ̇, Integrative Physiology Laboratory, Faculty of Physical Education, University of Brasília , Brasília , Brazil.

The cardiovascular responses to exercise are mediated by several interactive neural mechanisms, including central command, arterial baroreflex, and skeletal muscle mechano- and metaboreflex. In humans, muscle metaboreflex activation can be isolated via postexercise ischemia (PEI), which increases sympathetic nerve activity and partially maintains the exercise-induced increase in arterial blood pressure. Here, we describe a practical laboratory class using PEI as a simple and useful technique to teach cardiovascular physiology. Read More

Front Psychol 2018 27;9:2315. Epub 2018 Nov 27.

Movement Science, Australian Institute of Sport, Canberra, ACT, Australia.

Decision-making is an essential capability for success in team sport athletes. Good decision-making is underpinned by perceptual-cognitive skills that allow athletes to assess the environment and choose the correct choice from a number of alternatives. Previous research has demonstrated that decision-making can be trained "off-line" by exposing athletes to gameplay scenarios and having them make decisions based on the information presented to them. Read More

Proc Natl Acad Sci U S A 2018 Dec 10. Epub 2018 Dec 10.

Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309

In the proteasome holoenzyme, the hexameric ATPases (Rpt1-Rpt6) enable degradation of ubiquitinated proteins by unfolding and translocating them into the proteolytic core particle. During early-stage proteasome assembly, individual Rpt proteins assemble into the hexameric "Rpt ring" through binding to their cognate chaperones: Nas2, Hsm3, Nas6, and Rpn14. Here, we show that Rpt ring assembly employs a specific ubiquitination-mediated control. Read More

JMIR Mhealth Uhealth 2018 Dec 10;6(12):e10338. Epub 2018 Dec 10.

Department of Biomedical Engineering, Oregon Health & Science University, Portland, OR, United States.

Background: Wrist-worn activity monitors are often used to monitor heart rate (HR) and energy expenditure (EE) in a variety of settings including more recently in medical applications. The use of real-time physiological signals to inform medical systems including drug delivery systems and decision support systems will depend on the accuracy of the signals being measured, including accuracy of HR and EE. Prior studies assessed accuracy of wearables only during steady-state aerobic exercise. Read More

IEEE/ACM Trans Comput Biol Bioinform 2018 Dec 10. Epub 2018 Dec 10.

Implantable medical devices are safety-critical systems whose incorrect operation can jeopardize a patient's health, and whose algorithms must meet tight platform constraints like memory consumption and runtime. In particular, we consider here the case of implantable cardioverter defibrillators, where peak detection algorithms and various others discrimination algorithms serve to distinguish fatal from non-fatal arrhythmias in a cardiac signal. Motivated by the need for powerful formal methods to reason about the performance of arrhythmia detection algorithms, we show how to specify all these algorithms using Quantitative Regular Expressions (QREs). Read More

Eur J Pharm Sci 2018 Dec 7. Epub 2018 Dec 7.

La Paz University Hospital, Haematology and Haemotherapy Department, Madrid, Spain. Electronic address:

Trough factor (F) VIII level is a not reliable bleeding risk indicator to predict prophylaxis efficacy in severe haemophilia A (SHA), therefore, accurate biomarkers are much needed. Thrombelastography (TEG) monitors both thrombin and clot formation addressing the global haemostatic status but its usefulness to tailor prophylaxis in haemophilia has been poorly evaluated. In this study, correspondence between individual pharmacodynamic/pharmacokinetic profile of FVIII and joint condition, physical activity and bleeding phenotype of SHA patients under prophylactic treatment was assessed. Read More

World Neurosurg 2018 Dec 5. Epub 2018 Dec 5.

Vivian L. Smith Department of Neurosurgery, University of Texas Health Science Center at Houston, Texas USA. Electronic address:

Objectives: Anticoagulant therapy (ACT) after traumatic intracranial hemorrhage may lead to progression of hemorrhage, but in the presence of thromboembolic events the clinician must decide if the benefits outweigh the risks. Currently, no data exist to guide therapy in the acute setting.

Patients And Methods: We retrospectively identified all patients admitted to our institution with traumatic intracranial hemorrhage that received intravenous heparin, full dose enoxaparin, or warfarin during their initial hospitalization over a three-year period. Read More

Bioorg Med Chem 2018 Nov 15. Epub 2018 Nov 15.

Department of Biological Sciences, University of Pittsburgh, A320 Langley Hall, Pittsburgh, PA 15260, USA. Electronic address:

Over-expression of the Hsp70 molecular chaperone prevents protein aggregation and ameliorates neurodegenerative disease phenotypes in model systems. We identified an Hsp70 activator, MAL1-271, that reduces α-synuclein aggregation in a Parkinson's Disease model. We now report that MAL1-271 directly increases the ATPase activity of a eukaryotic Hsp70. Read More

Sleep 2018 Dec 5. Epub 2018 Dec 5.

CRUK Clinical Trials Unit, Institute of Cancer Sciences, University of Glasgow.

Study Objectives: Insomnia in cancer patients is prevalent, persistent and confers risk for physical and psychological disorder. We must better understand how insomnia develops in cancer patients and explore the main contributors to its chronicity so that insomnia management protocols can be integrated more effectively within cancer care. This study monitors the etiology of insomnia in breast cancer patients and identifies risk factors for its persistence. Read More

Acc Chem Res 2018 Dec 6. Epub 2018 Dec 6.

Department of Electrical and Computer Engineering , University of California San Diego , 9500 Gilman Drive , La Jolla , California 92093-0407 , United States.

Infrared photodetectors are essential to many applications, including surveillance, communications, process monitoring, and biological imaging. The short-wave infrared (SWIR) spectral region (λ = 1-3 μm) is particularly powerful for health monitoring and medical diagnostics because biological tissues show low absorbance and minimal SWIR autofluorescence, enabling greater penetration depth and improved resolution in comparison with visible light. However, current SWIR photodetection technologies are largely based on epitaxially grown inorganic semiconductors, which are costly, require complex processing, and impose cooling requirements incompatible with wearable electronics. Read More

Pilot Feasibility Stud 2018 29;4:179. Epub 2018 Nov 29.

7Department of Physical Therapy, University of Toronto, Toronto, Ontario Canada.

Background: Limited outdoor walking is a marker of frailty and a risk factor for decline in mobility and self-care functioning, social isolation, and reduced health-related quality of life (HRQL). Objectives were to evaluate the safety, feasibility, and preliminary effect of a supervised outdoor walking group and interactive workshop compared to the workshop alone in increasing outdoor walking activity and identify an optimal method for estimating outdoor walking activity among older adults who infrequently walk outdoors.

Methods: A pilot 2-parallel-group randomized controlled trial was conducted. Read More

Sensors (Basel) 2018 Dec 4;18(12). Epub 2018 Dec 4.

Tyndall National Institute, University College Cork, T12 R5CP Cork, Ireland.

The goal of real-time feedback on physiological changes, stress monitoring and even emotion detection is becoming a technological reality. People in their daily life experience varying emotional states, some of which are negative and which can lead to decreased attention, decreased productivity and ultimately, reduced quality of life. Therefore, having a solution that continuously monitors the physiological signals of the person and assesses his or her emotional well-being could be a very valuable tool. Read More

Sensors (Basel) 2018 Dec 4;18(12). Epub 2018 Dec 4.

Lab-STICC, CNRS, Université de Bretagne Sud, 56100 Lorient, France.

This paper presents a scalable approach to model uncertainties within a UAV (Unmanned Aerial Vehicle) embedded mission manager. It proposes a concurrent version of BFM models, which are Bayesian Networks built from FMEA (Failure Mode and Effects Analysis) and used by MDPs (Markov Decision Processes). The models can separately handle different applications during the mission; they consider the context of the mission including external constraints (luminosity, climate, etc. Read More

Animals (Basel) 2018 Dec 4;8(12). Epub 2018 Dec 4.

Geriatric Research Education Clinical Center, VA Maryland Health Care System, Baltimore, MD 21201, USA.

Although several studies have examined the effects of an owner's absence and presence on a dog's physiological responses under experimental conditions over short periods of time (minutes), little is known about the effects of proximity between humans and freely moving dogs under natural conditions over longer periods of time (days). The first aim of our study was to determine whether the combined data generated from the PetPace Collar and Actigraph Link accelerometer provide reliable pulse, respiration, and heart rate variability results during sedentary, light-moderate, and vigorous bouts in 11 freely moving dogs in a foster caretaker environment over 10⁻15 days. The second aim was to determine the effects of proximity (absence and presence of caretaker) and distance (caretaker and dog within 0⁻2 m) on the dogs' physiological responses. Read More

Nurs Crit Care 2018 Dec 2. Epub 2018 Dec 2.

The Critical Care Department, The Queen Elizabeth Hospital, King's Lynn, UK.

Background: Endotracheal tube cuff pressures should be maintained between 20 and 30 cm H O to prevent the aspiration of subglottic secretions past the cuff. Guidance recommends regular monitoring of the cuff pressure, performed using a handheld manometer/inflator. Poor technique can lead to transient deflation of the cuff, leading to the bolus aspiration of upper respiratory tract secretions, tracheal colonization and, ultimately, ventilator-associated pneumonia. Read More

Min Eng 2018 Nov;70(11):52-56

J.R. Patts, A.B. Cecala and J.A. Organiscak, members SME, are lead mechanical engineer, supervisory mining engineer and retired senior mining engineer, respectively, and J.P. Rider is lead research scientist at the National Institute for Occupational Safety and Health, Pittsburgh, PA, USA.

The U.S. National Institute for Occupational Safety and Health completed a 15-month study at an underground limestone mine crusher booth that evaluated three research parameters: (1) the effectiveness of a filtration and pressurization system for improving the air quality inside the operator booth, (2) the relative effectiveness of > 99 and > 95 experimental prototype filters in the system, and (3) the performance of three different cab pressure monitoring devices. Read More

Behav Brain Res 2018 Nov 28. Epub 2018 Nov 28.

Division of Biomedical Sciences, University of California Riverside, Riverside, CA 92521, United States; Department of Psychology & Program in Neuroscience, University of California Riverside, Riverside, CA 92521, United States. Electronic address:

Fear discrimination is critical for survival, while fear generalization is effective for avoiding dangerous situations. Overgeneralized fear is a typical symptom of anxiety disorders, including generalized anxiety disorder and posttraumatic stress disorder (PTSD). Previous research demonstrated that fear discrimination learning is mediated by prefrontal mechanisms. Read More

Rev Sci Instrum 2018 Nov;89(11):113305

GSI Helmholtzzentrum für Schwerionenforschung, Planckstrasse 1, 64291 Darmstadt, Germany.

The beam position appears in the transverse Schottky signal spectra of coasting beams at revolution frequency and its harmonics. In this contribution, we utilize this signal for beam position monitoring using regular shoe-box monitors at heavy ion synchrotron GSI SIS-18. Position resolution below 1 mm at 1 kHz rate for 10 mA current was obtained. Read More

Continuum (Minneap Minn) 2018 Dec;24(6):1776-1788

Purpose Of Review: This article focuses on the multiple neuromonitoring devices that can be used to collect bedside data in the neurocritical care unit and the methodology to integrate them into a multimodality monitoring system. The article describes how to apply the collected data to appreciate the physiologic changes and develop therapeutic approaches to prevent secondary injury.

Recent Findings: The neurologic examination has served as the primary monitor for secondary brain injury in patients admitted to the neurocritical care unit. Read More

Disabil Rehabil 2018 Dec 4:1-8. Epub 2018 Dec 4.

a Department of Physical Medicine, Rehabilitation and Occupational Medicine , Medical University of Vienna, Vienna , Austria.

Purpose: To systematically review literature for interventional studies and their impact on autonomic dysfunction assessed by heart rate variability in cancer patients.

Methods: Research was conducted using the databases Medline/Pubmed, Scopus, and Web of science from their inception to October 2017. Original articles with an interventional design that reported changes in at least one heart rate variability parameter as outcome parameter were included and described. Read More

Ann Vasc Surg 2018 Nov 27. Epub 2018 Nov 27.

Centers for Clinical Sciences Research, Charleston Area Medical Center Health Education and Research Institute, Charleston, WV.

Introduction: Post-surgical discharge complications result in increased hospital readmissions, cost, and patient dissatisfaction. Telehealth technology to monitor patients, especially those in geographically isolated areas, may reduce post-operative complications, improve health and financial outcomes.

Objective: The primary objective was to compare outcomes between patients that received Telehealth electronic monitoring (THEM) to those with routine discharge instructions and no monitoring, Standard Of Care (SOC). Read More

Int J Chron Obstruct Pulmon Dis 2018 24;13:3515-3527. Epub 2018 Oct 24.

Department of Rehabilitation Sciences, KU Leuven, Leuven, Belgium,

Purpose: Pulmonary rehabilitation (PR) enhances exercise tolerance in patients with COPD; however, improvements in physical activity (PA) are not guaranteed. This study explored the relationship between baseline exercise tolerance and changes in PA after PR.

Materials And Methods: Patient data from prospective clinical trials in the PR settings of Athens and Leuven (2008-2016) were analyzed. Read More

J Electrocardiol 2018 Nov - Dec;51(6):997-1002. Epub 2018 Jul 30.

Department of Biostatistics, University of Washington; 1959 NE Pacific Ave, Seattle, WA 98195, USA. Electronic address:

Background: Patch electrocardiographic (ECG) monitors permit extended noninvasive ambulatory monitoring. To guide use of these devices, information is needed about their performance. We sought to determine in a large general population sample the acceptability of patch ECG monitors, the yield of arrhythmia detection, and the consistency of findings in participants monitored twice. Read More

J Electrocardiol 2018 Nov - Dec;51(6):973-976. Epub 2018 Aug 25.

John Nasseff Neuroscience Specialty Clinic and the United Hospital Comprehensive Stroke Center, Allina Health, St. Paul, MN, United States of America.

Background: The use of insertable cardiac monitors (ICM) has increased the rate of detection of atrial fibrillation (AF) among cryptogenic stroke (CS) patients. We describe a single-center experience for AF detection among CS patients receiving ICMs upon discharge after the index stroke event and attempt to identify predictors for AF detection.

Methods: From April 2014 to October 2017, patients receiving ICMs for CS who underwent >60 days of monitoring were reviewed. Read More

Eur J Cardiovasc Nurs 2018 Nov 30:1474515118816930. Epub 2018 Nov 30.

3 School of Health Sciences, University of Akureyri, Iceland.

Background:: Physiological monitors are increasingly used for patient surveillance. Although nurses play a vital role in the observation, analysis and use of information obtained from these devices, difficulties in their use, coupled with the high frequency of false and nuisance monitor alarms, can lead to negative working conditions and threaten patient safety.

Aim:: With the purpose of promoting effective monitor use and ensuring patient safety, the aim was to explore both how cardiovascular nurses use monitors in patient surveillance and the effect that the monitors have on the nurses' work. Read More

Integr Environ Assess Manag 2018 Sep;14(5):571-577

Swedish Biodiversity Centre, Uppsala, Sweden.

This commentary discusses strategic environmental assessment (SEA) in the context of global environmental change and presents a brief overview of the science of social-ecological systems and the resilience thinking and practices that result from it. Resilience thinking and assessment have the potential to make a significant contribution to SEA, if SEA is applied (as intended) as a proactive tool for assessing development sustainability during the process of making plans, policies, and programs. So far, there is little indication that social-ecological system (SES) resilience ideas are being applied to SEA, and from a complex systems perspective, it seems that cognitive and social biases may be the primary barriers to both the improvement of SEA practice and the application of SES resilience science to SEA practice. Read More

Open Heart 2018 5;5(2):e000887. Epub 2018 Nov 5.

Abteilung Innere Medizin III, Department of Cardiology, Eberhard-Karls-Universität Tübingen, Tübingen, Germany.

Background: Patients with acute coronary syndrome (ACS) are at risk especially in the period shortly after the event. Alterations in respiratory control have been associated with adverse prognosis. The aim of our study was to assess if the nocturnal respiratory rate (NRR) is a predictor of mortality in patients with ACS presenting in the emergency department. Read More

Nat Protoc 2018 Nov 28. Epub 2018 Nov 28.

Department of Molecular Biology, University of Geneva, Geneva, Switzerland.

A better understanding of DNA replication initiation in human cells and how this process is altered upon DNA replication stress requires the ability to study origin firing genome wide. Previously described methods of mapping DNA replication origins in higher eukaryotes rely principally on fractionation of DNA fragments based on their size and, optionally, on the presence of ribonucleotides at their 5' end. Here, we describe a protocol for EdUseq-HU, a method for mapping early S-phase replication origins. Read More

J Am Heart Assoc 2018 Dec;7(23):e010256

4 Southlake Regional Health Centre Heart Rhythm Program Newmarket Ontario Canada.

Background Recent evidence shows an association between the level of physical activity and cardiovascular mortality and morbidity in patients with atrial fibrillation ( AF ). We sought to assess the impact of AF daily burden on the activity level of the patient who underwent pulmonary vein isolation. Methods and Results Patients enrolled in the DISCERN AF (Discerning Symptomatic and Asymptomatic Episodes Pre and Post Radiofrequency Ablation of Atrial Fibrillation) study all had insertable cardiac monitors, which provided the daily burden of atrial tachycardia and atrial fibrillation ( AT / AF ) and a corresponding activity level. Read More

Biomed Instrum Technol 2018 Nov./Dec.;52(6):433-441

Reduction of clinical alarms is a priority due to alarm fatigue and the high incidence of nonactionable alarms, especially those generated from physiological monitors. However, research on infusion pump alarm types and frequencies is limited. The purpose of this study was to establish a baseline for infusion pump alarm frequencies and duration in the hospital setting. Read More

Biomed Instrum Technol 2018 Nov./Dec.;52(6):477

J Anim Sci 2018 Nov 22. Epub 2018 Nov 22.

Division of Animal Sciences, University of Missouri, Columbia, Missouri.

Changes in locomotor activity of beef females during the 72 h prepartum were determined in 3 experiments: 1) a 2-yr study with spring-calving multiparous cows (Exp. 1; n = 34 and 27 for yr 1 and 2, respectively); 2) spring-calving primiparous (first pregnancy; n = 13) and multiparous (n = 21) dams (Exp. 2); and 3) fall-calving multiparous cows (Exp. Read More

Work 2018 Nov 22. Epub 2018 Nov 22.

Department of Environmental Health and Safety, University of Minnesota, Minneapolis, MN, USA.

The office ergonomic design from the late 1980's to the present has undergone significant changes during the transition from typewriters to the various human computer interfaces that evolved to the present day. Designs to accommodate various sized monitors and pointing devices have posed a challenge for ergonomist and designers of office workstations. Recent research suggesting adverse health effects associated with sedentary work environments have put additional pressure to incorporate the option to stand while working. Read More

J Anesth 2018 Nov 24. Epub 2018 Nov 24.

Department of Anesthesiology, Nihon University School of Medicine, 30-1, Oyaguchi Kami-Cho, Itabashi-Ku, 173-8610, Tokyo, Japan.

Purpose: The aim of this study was to compare TOF-Cuff™ (TOF-C) and TOF-Watch™ (TOF-W) data following rocuronium-induced neuromuscular block and its reversal with sugammadex.

Methods: Twenty elderly patients aged 68-82 years scheduled for surgery under general anesthesia were enrolled in this study. After induction of anesthesia, neuromuscular block resulting from administration of 0. Read More

J Vis Exp 2018 Nov 8(141). Epub 2018 Nov 8.

Research Group of Ecology and Behavioral Biology, Institute of Biology, University of Siegen.

Over the last decade, employing computer animations for animal behavior research has increased due to its ability to non-invasively manipulate the appearance and behavior of visual stimuli, compared to manipulating live animals. Here, we present the FishSim Animation Toolchain, a software framework developed to provide researchers with an easy-to-use method for implementing 3D computer animations in behavioral experiments with fish. The toolchain offers templates to create virtual 3D stimuli of five different fish species. Read More

Sci Total Environ 2018 Nov 12;655:423-433. Epub 2018 Nov 12.

Department of Civil & Environmental Engineering, University of Washington, Seattle, WA 98195, United States. Electronic address:

Outdoor air pollution is a major killer worldwide and the fourth largest contributor to the burden of disease in China. China is the most populous country in the world and also has the largest number of air pollution deaths per year, yet the spatial resolution of existing national air pollution estimates for China is generally relatively low. We address this knowledge gap by developing and evaluating national empirical models for China incorporating land-use regression (LUR), satellite measurements, and universal kriging (UK). Read More

Environ Sci Pollut Res Int 2018 Nov 23. Epub 2018 Nov 23.

Institute of High Mountain Biology, Žilina University, Tatranská Javorina, 7, SK-059 56, Slovak Republic.

Mercury and lead are deposited in the West Carpathians as long-range transported air pollution. The Alpine accentor (Prunella collaris) was recognized as a cost-effective biomonitor, and used to investigate the bioavailability of contaminants in large alpine areas. The outer tail feathers and blood of the alpine accentors were used for assessment of atmospheric mercury and lead contamination, respectively. Read More

Emerg Med J 2018 Nov 23. Epub 2018 Nov 23.

Emergency Medicine Research Group Edinburgh (EMERGE), Department of Emergency Medicine, Royal Infirmary of Edinburgh, Edinburgh, UK.

Syncope is a common reason for ED attendance and it presents a major management challenge with regard to the appropriate workup and disposition. Nearly 50% of patients are admitted, and for many this is unnecessary; clinical decision rules have not proven to decrease unnecessary admissions. The European Society of Cardiology has recently developed guidance for managing syncope in the ED. Read More

Waste Manag 2018 Nov 21. Epub 2018 Nov 21.

Institute of Environmental Sciences and Engineering, School of Civil and Environmental Engineering, National University of Sciences and Technology (NUST) Islamabad, Pakistan.

Rapid increase in the quantity of electronic/electrical-waste (e-waste) has become an emerging issue throughout the world. To avoid higher expenditures on safe disposal and recycling, large quantities of e-waste are being exported from developed to developing countries like Pakistan. Emerging issue of e-waste in Pakistan demands its effective management strategy for the country. Read More

JACC Clin Electrophysiol 2018 Nov 29;4(11):1383-1396. Epub 2018 Aug 29.

Cardiac Electrophysiology Section, Division of Cardiology, Department of Medicine, University of California, San Diego, La Jolla, California. Electronic address:

Insertable cardiac monitors (ICMs) are small, subcutaneously implanted devices offering continuous ambulatory electrocardiogram monitoring with a lifespan up to 3 years. ICMs have been studied and proven useful in selected cases of unexplained syncope and palpitations, as well as in atrial fibrillation (AF) management. The use of ICMs has greatly improved our ability to detect subclinical AF after cryptogenic stroke, and application of this technology is growing. Read More

J Reprod Dev 2018 Nov 22. Epub 2018 Nov 22.

Laboratory of Animal Resources and Development, Department of Northern Biosphere Agriculture, Faculty of Bioindustry, Tokyo University of Agriculture, Hokkaido 099-2493, Japan.

Mammalian oocyte quality degrades over time after ovulation in vitro, which can cause fatal defects such as chromosomal aneuploidy. As various oocyte manipulations employed in assisted reproductive technology are time consuming, post-ovulatory aging is a serious problem to overcome in reproductive medicine or ova research. In this study, we investigated the effects of postovulatory aging on the incidence of chromosome aneuploidy during meiosis II, with a focus on the expression of functional proteins from the spindle assembly checkpoint (SAC). Read More

Appl Opt 2018 Sep;57(27):7837-7856

It has been demonstrated by several authors that the optical turbulence parameters associated with a given adaptive optics (AO) run-the seeing angle and outer scale-can be determined from a statistical analysis of the commands of the system's deformable mirror (DM). The higher the accuracy on these parameters, the more we can make use of them, allowing for instance a better estimation of the seeing statistics at the telescope location or a more accurate assessment of the performance of the AO system. In the context of a point spread function reconstruction project (PSF-R) for the W. Read More

ACS Nano 2018 Nov 21. Epub 2018 Nov 21.

Department of Chemical Engineering , Stanford University , Stanford , California 94305-5025 , United States.

Skin-inspired wearable electronic/biomedical systems based on functional nanomaterials with exceptional electrical and mechanical properties have revolutionized wearable applications, such as portable Internet of Things, personalized healthcare monitors, human-machine interfaces, and even always-connected precise medicine systems. Despite these advancements, including the ability to predict and to control nanolevel phenomena of functional nanomaterials precisely and strategies for integrating nanomaterials onto desired substrates without performance losses, skin-inspired electronic nanosystems are not yet feasible beyond proof-of-concept devices. In this Perspective, we provide an outlook on skin-like electronics through the review of several recent reports on various materials strategies and integration methodologies of stretchable conducting and semiconducting nanomaterials, which are used as electrodes and active layers in stretchable sensors, transistors, multiplexed arrays, and integrated circuits. Read More

Am J Prev Med 2018 Dec 25;55(6):926-931. Epub 2018 Oct 25.

Office of Disease Prevention, NIH, Rockville, Maryland.

Introduction: To fulfill its mission, the NIH Office of Disease Prevention systematically monitors NIH investments in applied prevention research. Specifically, the Office focuses on research in humans involving primary and secondary prevention, and prevention-related methods. Currently, the NIH uses the Research, Condition, and Disease Categorization system to report agency funding in prevention research. Read More

Perioper Med (Lond) 2018 8;7:23. Epub 2018 Nov 8.

3Department of Pediatrics, NYU Langone Health, School of Medicine , New York, NY USA.

Background: Intravascular air embolism (AE) is a preventable but potentially catastrophic complication caused by intravenous tubing, trauma, and diagnostic and surgical procedures. The potentially fatal risks of arterial AE are well-known, and emerging evidence demonstrates impact of venous AEs on inflammatory response and coagulation factors. A novel FDA-approved in-line air detection and purging system was used to detect and remove air caused by administering a rapid fluid bolus during surgery. Read More

J Atr Fibrillation 2018 Jun-Jul;11(1):2055. Epub 2018 Jun 30.

St. Thomas Research Institute, Nashville, Tennessee.

Introduction: Parameters used to gauge the effectiveness of a cryoballoon lesion have been described that monitor the ablation at the time of balloon-to-pulmonary vein (PV) occlusion, during the cryoablation freeze, and at the thaw phase of the cryoablation. This study examines the balloon-to-PV occlusion step and monitors the completeness of occlusion using capnography to measure end-tidal CO2 (ETCO2). Specifically, the main objective was to determine if ETCO2 measurements can be used to quantify the amount of balloon-to-PV occlusion and to determine if acute ETCO2 parameters could predict long-term freedom from atrial fibrillation (AF). Read More

Chronobiol Int 2018 Nov 18:1-14. Epub 2018 Nov 18.

a Centre of Research, Education, Innovation and Intervention in Sport , University of Porto , Porto , Portugal.

The aim of the current study was to analyze the influence of the timing of training and matches, and match location, on sleep pattern and nocturnal cardiac autonomic activity in female soccer players. A total of 17 female soccer players (age: 21.6 ± 2. Read More