3,014 results match your criteria Mondor Disease


Treatment with golimumab or infliximab reduces health resource utilization and increases work productivity in patients with ankylosing spondylitis in the QUO-VADIS study, a large, prospective real-life cohort.

Int J Rheum Dis 2019 Apr 15. Epub 2019 Apr 15.

Merck & Co., Inc, Kenilworth, New Jersey.

Aim: We evaluated the effects of anti-tumor necrosis factor (TNF) agents on health economics in ankylosing spondylitis (AS) patients.

Methods: QUality of Life as Outcomes and its VAriation with DIsease States (QUO-VADIS) was a prospective observational study following bio-naïve AS patients (modified New York criteria) newly treated with golimumab (GLM) or infliximab (IFX; originator) in a clinical practice setting over 6 months. We evaluated use of concomitant medications, hospitalizations (in-patient care or acute care) and visits in day care and out-patient settings for the assessment of healthcare resource utilization (HCRU). Read More

View Article

Download full-text PDF

Source
https://onlinelibrary.wiley.com/doi/abs/10.1111/1756-185X.13
Publisher Site
http://dx.doi.org/10.1111/1756-185X.13526DOI Listing
April 2019
3 Reads

Clinical spectrum, evolution and management of autoimmune cytopenias associated with angioimmunoblastic T-cell lymphoma.

Eur J Haematol 2019 Apr 15. Epub 2019 Apr 15.

Service de médecine interne, Hôpital Henri-Mondor, Assistance Publique-Hôpitaux de Paris (AP-HP), Université Paris-Est, Créteil, France.

Objective: Angioimmunoblastic T-cell lymphoma (AITL) are frequently associated with autoimmune cytopenia (AIC). Whether such patients have a particular phenotype and require particular management is unclear.

Method: AITL patients from the multicentric database of the Lymphoma Study Association presenting with AIC during disease course were included and matched to AITL patients without AIC (1/5 ratio). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ejh.13239DOI Listing
April 2019
1 Read

[In-hospital management of acute complicated urinary tract infections].

Nephrol Ther 2019 Apr;15 Suppl 1:S27-S32

Unité de bactériologie, groupe hospitalier Henri-Mondor, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil cedex, France; Université Paris-Est-Créteil-Val-de-Marne, avenue du Général-de-Gaulle, 94010 Créteil cedex, France.

Upper tract urinary tract infections that require hospitalization have been the focus of national recommendations in 2018 by the French society of infectious diseases (Spilf). We here propose to discuss several complex-challenging situations: severe infection with sepsis, pyelonephritis in the pregnant woman, management of infections involving multiresistant bacteria and infection in polycystic kidney disease. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nephro.2019.02.002DOI Listing
April 2019
1 Read

Local miscommunications between glomerular cells as potential therapeutic targets for crescentic glomerulonephritides.

Nephrol Ther 2019 Apr;15 Suppl 1:S1-S5

Inserm, Paris Cardiovascular Centre (Parcc), 56, rue Leblanc, 75015 Paris, France; Université Paris Descartes, Sorbonne Paris Cité, 12, rue de l'École-de-Médecine, 75006 Paris, France. Electronic address:

Necrotizing and crescentic rapidly progressive glomerulonephritis or crescentic glomerulonephritis is one of the severest forms of acquired glomerular diseases with significant mortality. Risk of end-stage renal failure at 5 years is near 30%, with a number of patients developing chronic kidney disease. Currently, autoimmune crescentic glomerulonephritides are treated with broad-spectrum immunosuppression inducing remission of the injury in the majority of patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nephro.2019.03.006DOI Listing
April 2019
1 Read

PAPASH, PsAPASH and PASS autoinflammatory syndromes: Phenotypic heterogeneity, common biological signature and response to immunosuppressive regimens.

Br J Dermatol 2019 Apr 13. Epub 2019 Apr 13.

Department of Dermatology, APHP Hôpital St-Louis, Paris.

Hidradenitis suppurativa (HS) is a chronic inflammatory disease of skin appendages, commonly associating with other conditions including spondyloarthritis, and is a major component of severe cutaneo-articular autoinflammatory syndromes (AIS), called PAPASH (Pyogenic Arthritis, pyoderma gangrenosum/PG, Acne, HS), PsAPASH (Psoriatic Arthritis, PG, Acne, HS) and PASS (Ankylosing Spondylitis, Acne, PG and HS). The clinical phenotypes of these AIS are ill-defined and unlike PASH or PAPA syndromes, still lack any biological or genetic marker. Moreover, their optimal therapeutic management remains unclear. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bjd.18003DOI Listing
April 2019
1 Read

Modeling the Outcome of Systematic TPMT Genotyping or Phenotyping Before Azathioprine Prescription: A Cost-Effectiveness Analysis.

Mol Diagn Ther 2019 Apr 8. Epub 2019 Apr 8.

Service de Biochimie, Hôpital Européen Georges Pompidou, Assistance Publique-Hôpitaux de Paris, Université Paris Descates, 20, rue Leblanc, 75015, Paris, France.

Background: Thiopurine S-methyltransferase (TPMT) testing, either by genotyping or phenotyping, can reduce the incidence of adverse severe myelotoxicity episodes induced by azathioprine. The comparative cost-effectiveness of TPMT genotyping and phenotyping are not known.

Objective: Our aim was to assess the cost-effectiveness of phenotyping-based dosing of TPMT activity, genotyping-based screening and no screening (reference) for patients treated with azathioprine. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s40291-019-00398-xDOI Listing

Cohort profile The ESC-EORP EURO-ENDO (European Infective Endocarditis) registry.

Eur Heart J Qual Care Clin Outcomes 2019 Apr 8. Epub 2019 Apr 8.

Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, UK.

Aims: The European Society of cardiology (ESC) EURObservational Research Programme (EORP) European Endocarditis (EURO-ENDO) registry aims to study the care and outcomes of patients diagnosed with infective endocarditis and compare findings with recommendations from the 2015 ESC Clinical Practice Guidelines for the management of infective endocarditis and data from the 2001 Euro Heart Survey.

Methods And Results: Patients (n = 3116) aged over 18 years with a diagnosis of infective endocarditis based on the ESC 2015 infective endocarditis diagnostic criteria were prospectively identified between January 1st, 2016 and March 31st, 2018. Individual patient data were collected across 156 centres and 40 countries. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ehjqcco/qcz018DOI Listing
April 2019
1 Read

Comparison of Different Nodal Staging in Patients With Locally Advanced Mid-low Rectal Cancer After Long-term Neoadjuvant Chemoradiation Therapy.

Anticancer Res 2019 Apr;39(4):2113-2120

Unit of Digestive, Hepato-Pancreato-Biliary Surgery and Liver Transplantation, Henri Mondor Hospital, AP-HP, University of Paris Est, UPEC, Créteil, France

Background/aim: The aim of this study was to compare the ability of different lymph nodal staging systems to predict cancer recurrence in a multicenter European series of patients who underwent proctectomy after neoadjuvant chemoradiotherapy for locally advanced rectal cancer.

Patients And Methods: Data on 170 consecutive patients undergoing proctectomy after neoadjuvant therapy for cT3-4 or cN+ rectal adenocarcinoma were retrieved from the European MRI and Rectal Cancer Surgery database. The prognostic role of the number of retrieved and examined nodes, nodal ratio, and log odds of positive lymph nodes (LODDS) was analyzed and compared by receiver operating characteristic curves, Pearson test, and univariate and multivariate analysis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21873/anticanres.13324DOI Listing
April 2019
1 Read

Validation of a Physicians Global Assessment (PGA) tool for vitiligo extent: results of an international vitiligo expert meeting.

Pigment Cell Melanoma Res 2019 Apr 3. Epub 2019 Apr 3.

Department of Dermatology, Ghent University Hospital, Ghent, Belgium.

Currently, vitiligo lacks a validated Physician Global Assessment (PGA) for disease extent. This PGA can be used to stratify and interpret the numeric scores obtained by the Vitiligo Extent Score (VES). We investigated the interrater reliability of a 5-point PGA scale during an international vitiligo workshop. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/pcmr.12784DOI Listing
April 2019
2 Reads
4.619 Impact Factor

Right-sided vs. left-sided obstructing colonic cancer: results of a multicenter study of the French Surgical Association in 2325 patients and literature review.

Int J Colorectal Dis 2019 Apr 2. Epub 2019 Apr 2.

Sorbonne Université, Assistance Publique Hôpitaux de Paris, Department of Digestive and Hepatopancreato-Biliary Surgery, Pitié Salpêtrière University Hospital, 47-83 Bd de l'Hôpital, 75651, Paris Cedex 13, France.

Purpose: Few studies compared management and outcomes of obstructing colonic cancer (OCC), according to the tumor site. Our aim was to compare patient and tumor characteristics, postoperative and pathological results, and oncological outcomes after emergency management of right-sided vs. left-sided OCC. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00384-019-03286-2DOI Listing
April 2019
3 Reads

Safety and efficacy of the combination simeprevir-sofosbuvir in HCV genotype 1- and 4-mono-infected patients from the French ANRS CO22 hepather cohort.

BMC Infect Dis 2019 Apr 2;19(1):300. Epub 2019 Apr 2.

Université Paris Descartes ; APHP, Unité d'Hépatologie, Hôpital Cochin ; INSERM U-818 et USM20, Institut Pasteur, Paris, France.

Background: Although real-life results of sofosbuvir/simeprevir have been extensively reported from the United States, data from other geographical areas are limited. In the French observational cohort, ANRS CO22 HEPATHER, 9432 patients were given the new oral antivirals from December 2013 to June 30, 2018. We report the results of sofosbuvir/simeprevir in genotypes 1- and 4-infected patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12879-019-3923-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446259PMC
April 2019
1 Read

Transthyretin cardiac amyloidosis in continental Western Europe: an insight through the Transthyretin Amyloidosis Outcomes Survey (THAOS).

Eur Heart J 2019 Apr 1. Epub 2019 Apr 1.

Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy.

Aims: Transthyretin amyloidosis (ATTR amyloidosis) is a heterogeneous disorder with cardiac, neurologic, and mixed phenotypes. We describe the phenotypic and genotypic profiles of this disease in continental Western Europe as it appears from the Transthyretin Amyloidosis Survey (THAOS).

Methods And Results: THAOS is an ongoing, worldwide, longitudinal, observational survey established to study differences in presentation, diagnosis, and natural history in ATTR amyloidosis subjects. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/eurheartj/ehz173DOI Listing
April 2019
5 Reads

High prevalence of altered sudomotor function in homozygous sickle cell patients: influence of age and anaemia.

Br J Haematol 2019 Apr 1. Epub 2019 Apr 1.

Service d'Explorations Fonctionnelles Multidisciplinaires, Assistance Publique - Hôpitaux de Paris (AP-HP), Hôpital Tenon, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bjh.15892DOI Listing
April 2019
3 Reads

[The staging model (or evolutionary stages) applied to bipolar disorder].

Authors:
J Scott C Henry

Encephale 2018 Dec;44(6S):S30-S33

Institut pasteur, unité perception et mémoire, F-75015 Paris, France - Université Paris-Est, UMR S955, UPEC, F-94000 Créteil, France - AP-HP, Hôpital Henri-Mondor, Albert-Chenevier, pôle de psychiatrie, F-94000 Créteil, France.

In psychiatry, clinical staging raises awareness of the need to understand disease trajectories and heterotypic continuity; it draws attention to individuals at risk of developing disorders, such as those with a family history or subsyndromal presentations; and it actively promotes greater attention to prevention strategies and interventions for individuals at ultra-high risk of developing a severe mental disorder. Staging paradigms have been increasingly applied in early intervention in psychoses, but there are issues in broadening the scope of clinical staging to the more prevalent affective disorders. For example, it is potentially more complex to devise a model that considers the varying clinical presentations of the late prodromal stage of bipolar disorder and where to locate depressive episodes that precede the first manic episode and how to describe subthreshold manic syndromes, especially hypomania. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00137006193007
Publisher Site
http://dx.doi.org/10.1016/S0013-7006(19)30076-4DOI Listing
December 2018
3 Reads

Physiological Evaluation for Endurance Exercise Prescription in Sickle Cell Disease.

Med Sci Sports Exerc 2019 Mar 25. Epub 2019 Mar 25.

Univ Lyon, UJM-Saint-Etienne, Inter-university Laboratory of Human Movement Sciences, EA7424, Saint-Etienne, France.

Purpose: While strenuous exercise may expose sickle cell disease (SCD) patients to risks of vaso-occlusive crisis (VOC), evidence suggests that regular endurance exercise may be beneficial. To test i) the safety and usefulness of a submaximal incremental exercise in evaluating physical ability of SCD patients and identify a marker for the management of endurance exercise, and ii) the feasibility of endurance exercise sessions in SCD patients.

Methods: Twenty adults with sickle cell disease (12 men and 8 women) performed a submaximal incremental exercise stopped as soon as blood lactate concentration ([lactate]b) reached ≥ 4 mmolL and used to determine the first lactate threshold (LT1). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1249/MSS.0000000000001993DOI Listing
March 2019
1 Read

Myoglobinopathy is an adult-onset autosomal dominant myopathy with characteristic sarcoplasmic inclusions.

Nat Commun 2019 03 27;10(1):1396. Epub 2019 Mar 27.

Centre for Medical Research, University of Western Australia, Harry Perkins Institute of Medical Research, Perth, 6000, WA, Australia.

Myoglobin, encoded by MB, is a small cytoplasmic globular hemoprotein highly expressed in cardiac myocytes and oxidative skeletal myofibers. Myoglobin binds O facilitates its intracellular transport and serves as a controller of nitric oxide and reactive oxygen species. Here, we identify a recurrent c. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-019-09111-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437160PMC
March 2019
3 Reads

Delayed hemolytic transfusion reaction in the French hemovigilance system.

Transfus Clin Biol 2019 May 9;26(2):109-111. Epub 2019 Mar 9.

Agence nationale de sécurité du médicament et des produits de santé (ANSM), 93285 Saint-Denis cedex, France.

In France, reporting of adverse events related, or likely to be related, to transfusion is mandatory. Since its creation in 1993, the French hemovigilance system has contributed to a better recognition of unappreciated risks like delayed hemolytic transfusion reactions (DHTR) in sickle-cell disease (SCD) patients. Long under-reported or misclassified, reports of this serious complication of transfusion have improved, particularly through the dissemination of information within the hemovigilance network. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tracli.2019.03.001DOI Listing
May 2019
2 Reads

Incidence and survival outcomes in patients with upper urinary tract urothelial carcinoma diagnosed with variant histology and treated with nephroureterectomy.

BJU Int 2019 Mar 25. Epub 2019 Mar 25.

Klinik für Urologie, Luzerner Kantonsspital, Lucerne, Switzerland.

Objective: To evaluate the incidence and survival outcomes of histological variants of upper tract urothelial carcinoma (UTUC) treated with radical nephroureterectomy (RNU).

Materials And Methods: We retrospectively analysed data from 1610 patients treated with RNU for clinically non-metastatic UTUC between 1990 and 2016 in several centres participating in the UTUC Collaboration. Histological variants were classified as micropapillary, squamous, sarcomatoid and other, including other rare variants (<10 cases for each). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bju.14751DOI Listing

A HSD17B13 variant protects from hepatocellular carcinoma development in alcoholic liver disease.

Hepatology 2019 Mar 25. Epub 2019 Mar 25.

Centre de Recherche des Cordeliers, Sorbonne Université, Inserm, USPC, Université Paris Descartes, Université Paris Diderot, Université Paris 13, Functional Genomics of Solid Tumors laboratory, F-75006, Paris, France.

Introduction: Recently, a loss of function variant (rs72613567) in 17-beta-hydroxysteroid dehydrogenase 13 (HSD17B13) has been identified as protective of non-alcoholic and alcoholic liver disease (ALD). However, the role of this SNP in the development of HCC is currently unknown.

Materials And Methods: 3,315 European patients with HCC (n=1,109) or without HCC but with chronic liver disease (CLD, n=2,206) from 4 centers were analyzed either by whole-exome sequencing (exploratory cohort, 285 HCC) or genotyped for HSD17B13 rs72613567 (validation cohort, 824 HCC and all CLD). Read More

View Article

Download full-text PDF

Source
https://onlinelibrary.wiley.com/doi/abs/10.1002/hep.30623
Publisher Site
http://dx.doi.org/10.1002/hep.30623DOI Listing
March 2019
9 Reads
11.055 Impact Factor

A Toll-like receptor 2 genetic variant modulates occurrence of bacterial infections in patients with sickle cell disease.

Br J Haematol 2019 Mar 25. Epub 2019 Mar 25.

INSERM U955, Centre Hospitalier Universitaire Henri Mondor, Créteil, France.

Despite adequate immunization and penicillin prophylaxis, bacterial infections remain a leading cause of morbidity and mortality in patients with sickle cell disease (SCD). Besides hyposplenism, inflammatory and genetic factors might modulate their susceptibility to bacterial infections. We performed a candidate gene association of single nucleotide polymorphisms (SNPs) located in Toll-like receptor (TLR) genes, encoding prominent molecules for innate immune responses, with the occurrence of bacterial infections in patients with SCD. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bjh.15875DOI Listing
March 2019
1 Read

Intracranial aneurysms in sickle cell disease: Aneurysms characteristics and modalities of endovascular approach to treat these patients.

J Neuroradiol 2019 Mar 20. Epub 2019 Mar 20.

CHU de Henri-Mondor, Créteil, AP-HP, service de neuroradiologie diagnostique et thérapeutique, 94000 Créteil, France.

Introduction: The neurological complications of Sickle Cell Disease (SCD) include cerebral infarction and haemorrhage with rarely subarachnoid haemorrhage due to cerebral aneurysms.

Materials And Methods: In our interventional department, working with SCD referral department, we reported our experience concerning management of adult's patients with cerebral aneurysms. We identified 26 adults with 48 intracranial aneurysms documented by imaging. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S01509861193020
Publisher Site
http://dx.doi.org/10.1016/j.neurad.2019.03.001DOI Listing
March 2019
8 Reads

FcRn-Dependent Transcytosis of Monoclonal Antibody in Human Nasal Epithelial Cells In Vitro: A Prerequisite for a New Delivery Route for Therapy?

Int J Mol Sci 2019 Mar 19;20(6). Epub 2019 Mar 19.

Université de Tours, EA 7501 GICC, F-37032 Tours, France.

Monoclonal antibodies (mAbs) are promising therapies to treat airway chronic inflammatory disease (asthma or nasal polyps). To date, no study has specifically assessed, in vitro, the potential function of neonatal Fc receptor (FcRn) in IgG transcytosis through the human nasal airway epithelium. The objective of this study was to report the in vitro expression and function of FcRn in nasal human epithelium. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms20061379DOI Listing
March 2019
1 Read

Prophylactic implantable cardioverter-defibrillator in the very elderly.

Europace 2019 Mar 19. Epub 2019 Mar 19.

Paris Cardiovascular Research Center, Paris, France.

Aims: Current guidelines do not propose any age cut-off for the primary prevention implantable cardioverter-defibrillator (ICD). However, the risk/benefit balance in the very elderly population has not been well studied.

Methods And Results: In a multicentre French study assessing patients implanted with an ICD for primary prevention, outcomes among patients aged ≥80 years were compared with <80 years old controls matched for sex and underlying heart disease (ischaemic and dilated cardiomyopathy). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz041DOI Listing
March 2019
4 Reads

Impact of hypertensive emergency and complement rare variants on presentation and outcome of atypical hemolytic uremic syndrome.

Haematologica 2019 Mar 19. Epub 2019 Mar 19.

APHP, Hôpital Européen Georges Pompidou, laboratoire d'Immunologie, INSERM, UMR_S 1138.

Atypical hemolytic uremic syndrome is a prototypic thrombotic microangiopathy attributable to complement dysregulation. Hypertensive emergency, characterized by elevation of systolic (>180mmHg) or diastolic (>120mmHg) blood pressure together with end-organ damage, can cause thrombotic microangiopathy which may mimic atypical hemolytic uremic syndrome. We sought to retrospectively evaluate the clinical, biological and complement genetic characteristics of 76 and 61 atypical hemolytic uremic syndrome patients with and without hypertensive emergency, respectively. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3324/haematol.2019.216903DOI Listing
March 2019
4 Reads

Lyme neuroborreliosis in children: Report of nine cases and a review of the literature.

Arch Pediatr 2019 Apr 15;26(3):133-137. Epub 2019 Mar 15.

Service de microbiologie, hôpital Necker-enfants-malades, Assistance publique-hôpitaux de Paris, 149, rue de Sèvres, 75015 Paris, France.

Lyme neuroborreliosis is a bacterial infection caused by the dissemination and proliferation of a Borrelia species in the central nervous system. Neuroborreliosis occurs after transmission of the pathogen from an infected tick to a human host during a tick bite. We report nine cases of pediatric neuroborreliosis collected by the National Observatory of Pediatric Bacterial Meningitis in France between 2001 and 2012. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.arcped.2019.02.010DOI Listing
April 2019
1 Read

[Parkinson's disease: 10 key messages].

Authors:
Philippe Rémy

Rev Prat 2018 May;68(5):522

service de neurologie, hôpital Henri-Mondor, AP-HP, Créteil, France.

View Article

Download full-text PDF

Source

[Centers for the management of Parkinson's disease].

Rev Prat 2018 May;68(5):520-521

Centre expert Parkinson, service de neurologie, CHU Henri-Mondor, AP-HP, Créteil ; université Paris-Est, faculté de médecine, UPEC, Créteil ; Inserm U955-E01, IMRB, neuropsychologie interventionnelle, Créteil, France, département d'études cognitives, École normale supérieure, PSL Research University, Paris, France.

View Article

Download full-text PDF

Source
May 2018
3 Reads

[Non-motor symptoms of Parkinson disease and their management].

Rev Prat 2018 May;68(5):508-512

Centre expert Parkinson, hôpital Henri-Mondor, service de neurologie.

Non-motor symptoms of parkinson's disease and their management. Non-motor symptoms of Parkinson's disease are often the first manifestations of the disease before diagnosis is made. These symptoms are diverse: psychic manifestations such as anxiety, depression or behavioral disorders, dysautonomia, pain, alteration of smell or vision, and sleep disturbances. Read More

View Article

Download full-text PDF

Source
May 2018
2 Reads

[Transfusion: the case of sickle cell patients].

Rev Prat 2018 Nov;68(9):1034-1035

Unité des maladies génétiques du globule rouge, hôpital Henri-Mondor, Créteil.

View Article

Download full-text PDF

Source
November 2018
3 Reads

[Management of spondyloarthritis].

Rev Prat 2018 Sep;68(7):740-746

AP-HP, service de rhumatologie, hôpital Henri-Mondor, Créteil, France ; université Paris-Est-Créteil, EA 7379 - EpidermE, Créteil, France.

Management of spondyloarthritis. Management of spondyloarthritis is based on early diagnosis, patient information and education, a tight control of disease activity, screening and treatment of comorbidities, physiotherapy in axial forms, and the use of various drugs. Non-steroidal anti-inflammatory drugs remain the first line therapy, used in an "on demand" strategy. Read More

View Article

Download full-text PDF

Source
September 2018
2 Reads

[Gerontological evaluation benefits for very older people with cardiovascular disease].

Presse Med 2019 Feb 8;48(2):120-126. Epub 2019 Mar 8.

AP-HP, hôpitaux universitaires Pitié-Salpétrière-Charles-Foix, hôpital Charles-Foix, service de gériatrie ambulatoire, 94200 Ivry-sur-Seine, France. Electronic address:

The multidimensional, multiprofessional gerontological evaluation helps identify geriatric syndromes and situations of fragility. This is a first step to establish a plan of care and assistance, to reduce the risk of falls, hospitalization, entry into institutions and to prevent a decline in independence. Older people with cardiovascular disease such as heart failure are at very high risk of repeated hospitalizations, with an average of 45% of patients re-hospitalized in the year following all-cause hospitalization. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.lpm.2019.02.004DOI Listing
February 2019

Hyperbilirubinemia as a Predictor of Appendiceal Perforation: A Systematic Review and Diagnostic Test Meta-Analysis.

J Clin Med Res 2019 Mar 13;11(3):171-178. Epub 2019 Feb 13.

Department of General and Colorectal Surgery, Northampton General Hospital NHS Trust, Northampton, UK.

Background: Misdiagnosis of the severity of acute appendicitis may lead to perforation and can consequently result in increased morbidity and mortality. In this study, the role of hyperbilirubinemia as a predictor of perforation is assessed by performing a meta-analysis of diagnostic accuracy.

Methods: A systematic search of the literature published over the past 20 years was performed using the EMBASE, PubMed, Cochrane library, and Google Scholar databases. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14740/jocmr3724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396786PMC
March 2019
4 Reads

Outcomes of Older Patients (≥60 years) with New-Onset Idiopathic Nephrotic Syndrome Receiving Immunosuppressive Regimen: A Multicentre Study of 116 Patients.

J Clin Med 2019 Mar 2;8(3). Epub 2019 Mar 2.

Département de Néphrologie et Transplantation d'Organes, Centre de Référence des Maladies Rénales Rares, Centre Hospitalier Universitaire de Toulouse, 31000 Toulouse, France.

Because of its rarity, renal presentation and outcomes of idiopathic nephrotic syndrome (INS; minimal changes disease or focal and segmental glomerulosclerosis) has poorly been described in elderly patients, precluding an individualized therapy procedure. Whether immunosuppressive regimens formerly designed in children and young adults are safe and efficient in elderly remains elusive. In a large multicentric retrospective study that included 116 patients with INS and onset ≥ 60 years of age, we showed that cumulative incidence of renal response was 95% after frontline therapy, with an age-dependent median time-to-response (60 days before 70 years of age at the onset vs. Read More

View Article

Download full-text PDF

Source
https://www.mdpi.com/2077-0383/8/3/298
Publisher Site
http://dx.doi.org/10.3390/jcm8030298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463053PMC
March 2019
8 Reads

Prediction of survival with second-line therapy in biliary tract cancer: Actualisation of the AGEO CT2BIL cohort and European multicentre validations.

Eur J Cancer 2019 Apr 1;111:94-106. Epub 2019 Mar 1.

Methodology and Quality of Life in Oncology Unit, Besançon University Hospital, Besançon, France; Univ. Bourgogne Franche-Comté, INSERM, EFS BFC, UMR1098, Interactions Hôte-Greffon-Tumeur/Ingénierie Cellulaire et Génique, F-25000, Besançon, France. Electronic address:

Background: The benefit of second-line chemotherapy (L2) over standard first-line (L1) gemcitabine plus cisplatin (GEMCIS) or oxaliplatin (GEMOX) chemotherapy in advanced biliary tract cancer (aBTC) is unclear. Our aim was to identify and validate prognostic factors for overall survival (OS) with L2 in aBTC to guide clinical decisions in this setting.

Methods: We performed a retrospective analysis of four prospective patient cohorts: a development cohort (28 French centres) and three validation cohorts from Italy, UK and France. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejca.2019.01.019DOI Listing
April 2019
4 Reads
5.417 Impact Factor

Fabry disease in cardiology practice: Literature review and expert point of view.

Arch Cardiovasc Dis 2019 Apr 28;112(4):278-287. Epub 2019 Feb 28.

French Referral Centre for Fabry Disease, Division of Medical Genetics, hôpital Raymond-Poincare, AP-HP, 92380 Garches, France; Inserm U1179, University of Versailles, 78180 Montigny, France.

Fabry disease is an X-linked progressive multisystemic genetic sphingolipidosis caused by deficient activity of lysosomal α-galactosidase A. Men aged>30 years and women aged>40 years most often present with unexplained left ventricular hypertrophy, usually concentric and non-obstructive, but sometimes mimicking sarcomeric hypertrophic cardiomyopathy, particularly when isolated, as in the cardiac or late-onset variant of the disease. In hypertrophic cardiomyopathy cohorts, up to 1% of patients have been diagnosed with Fabry disease. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S18752136193003
Publisher Site
http://dx.doi.org/10.1016/j.acvd.2019.01.002DOI Listing
April 2019
3 Reads

Impact of Conversion from Laparoscopy to Open Surgery in Patients with Right Colon Cancer.

Am Surg 2019 Feb;85(2):177-182

Conversion to open surgery is reported in up to 20 per cent of laparoscopic colectomies for cancer. This study aims to compare postoperative outcomes and survival between converted and successful laparoscopic right colectomy for cancer. Records of patients who underwent laparoscopic right colectomy for cancer between 2005 and 2015 were retrieved from the CLermontFerrand Ircad Mondor Hopital European Tours (CLIMHET) database. Read More

View Article

Download full-text PDF

Source
February 2019
1 Read

Ustekinumab for skin reactions associated with anti-tumor necrosis factor-α agents in patients with inflammatory bowel diseases: A single-center retrospective study.

J Dermatol 2019 Apr 28;46(4):322-327. Epub 2019 Feb 28.

Department of Dermatology, Courlancy Clinic, Rheims, France.

Anti-tumor necrosis factor (TNF)-α agents may induce skin reactions, in particular in patients with inflammatory bowel diseases (IBD). The objective of this study was to determine the efficacy of ustekinumab in these patients. IBD patients facing therapeutic issues because of cutaneous reactions or tolerance issues, consequently treated with ustekinumab in our department, were included. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/1346-8138.14816DOI Listing
April 2019
1 Read

Congenital prepubic sinus presenting with purulent discharge after circumcision: a case report.

J Med Case Rep 2019 Feb 28;13(1):46. Epub 2019 Feb 28.

Department of Pathology, Patomer Pathological Cytological Research Center, Istanbul, TR, Turkey.

Background: Congenital prepubic sinus is a rare anomaly found in the midline of the lower abdomen. Congenital prepubic sinus is usually asymptomatic in neonates, and a diagnosis is often achieved later in life after spontaneous extrusion of purulent material from the pre-existing hole in the pubic region. We present a case of congenital prepubic sinus presenting with purulent discharge after circumcision. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13256-019-2019-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393969PMC
February 2019

[Acute kidney injury related to acute vascular disorders].

Rev Prat 2018 Feb;68(2):166-169

Service de néphrologie et transplantation, CHU Henri-Mondor, université Paris-Est Créteil, Créteil, France.

Acute kidney injury related to acute vascular disorders. A broad spectrum of vascular disease characterized by primary vessel involvement may be associated with acute renal failure. These diseases are usually classified according to the size of the injured vessel that include the small vessels (thrombotic microangiopathy, kidney injury due to malignant hypertension, scleroderma renal crisis, and cholesterol crystal embolism disease), the medium vessels (polyarteritis nodosa) or the large size vessels (acute renal infarction). Read More

View Article

Download full-text PDF

Source
February 2018

Not only disease activity but also chronic hypertension and overweight are determinants of pregnancy outcomes in patients with systemic lupus erythematosus.

Lupus 2019 Apr 24;28(4):529-537. Epub 2019 Feb 24.

1 Department of Nephrology, Hypertension and Dialysis, Hospices Civils de Lyon, Lyon, France.

Introduction: Pregnancies in women with lupus nephritis are at high-risk of complications, while scarcity of scientific knowledge on prognostic factors impedes a fair medical counseling. We aimed to identify determinants associated with maternal and fetal complications.

Materials: We retrospectively reviewed medical charts of pregnancies that lasted more than 22 weeks in 66 patients with pre-existing lupus nephritis between 2004 and 2013 in France. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0961203319832097DOI Listing
April 2019
1 Read

Mondor's Disease.

Intern Med 2019 Feb 25. Epub 2019 Feb 25.

Ibaraki Prefectural Central Hospital, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2169/internalmedicine.2024-18DOI Listing
February 2019

Early diagnosis of ATTR amyloidosis through targeted follow-up of identified carriers of TTR gene mutations.

Amyloid 2019 Feb 22:1-7. Epub 2019 Feb 22.

k Department of Neurology , Kumamoto University , Kumamoto , Japan.

Diagnosis in the early stages of hereditary transthyretin (ATTR) amyloidosis is imperative to support timely treatment to prevent or delay disease progression. Genetic testing in the setting of genetic counselling enables identification of carriers of a TTR gene mutation who are therefore at risk of developing TTR-associated disease. Knowledge of different genotypes and how they manifest in symptomatic disease should facilitate development of a structured and targeted approach to enable diagnosis of symptomatic disease in ATTR amyloidosis mutation carriers on the first manifestation of the earliest detectable sign or symptom. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/13506129.2018.1556156DOI Listing
February 2019
8 Reads

Six-year follow-up of vitiligo patients successfully treated with autologous non-cultured melanocyte-keratinocyte transplantation.

J Eur Acad Dermatol Venereol 2019 Feb 22. Epub 2019 Feb 22.

Department of Dermatology, APHP, Hôpital Henri Mondor, Université Paris-Est, Créteil, France.

Background: Although autologous non-cultured melanocyte-keratinocyte transplantation is a treatment option for stable vitiligo, there is lack of long-term maintenance data for this specific treatment.

Objective: To search for factors associated with long-term maintenance of patients with stable vitiligo successfully treated with melanocyte-keratinocyte transplantation.

Methods: This was a single-centre retrospective study including stable vitiligo patients who underwent successful melanocyte-keratinocyte transplantation in the National Center for Vitiligo, Riyadh, Saudi Arabia, between 1 January 2004 and 30 June 2015. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jdv.15411DOI Listing
February 2019

[Surgery for advanced stage ovarian cancer: Article drafted from the French Guidelines in oncology entitled "Initial management of patients with epithelial ovarian cancer" developed by FRANCOGYN, CNGOF, SFOG, GINECO-ARCAGY under the aegis of CNGOF and endorsed by INCa].

Gynecol Obstet Fertil Senol 2019 02 19;47(2):197-213. Epub 2019 Feb 19.

IMRB, U955 Inserm, service de gynécologie obstétrique et médecine de la reproduction, centre hospitalier intercommunal de Créteil, institut Mondor de recherche biomédicale, 94000 Créteil, France. Electronic address:

Debulking surgery is the key step of advanced stage ovarian cancer treatment with chemotherapy. The quality of surgical resection is the main prognosis factor, thus a complete resection must be achieved (grade A) in an expert center (grade B). Surgery for stage IV is possible and has a benefit in case of complete peritoneal resection (LoE3). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.gofs.2019.01.003DOI Listing
February 2019
1 Read

Efficacy, tolerability and safety of low volume bowel preparations in Inflammatory Bowel Diseases: The French multicentre CLEAN study.

J Crohns Colitis 2019 Feb 13. Epub 2019 Feb 13.

Department of Gastroenterology, University Hospital of Besançon, University Bourgogne Franche-Comté, Besançon, France.

Background: Standard high-volume polyethylene glycol (PEG) bowel preparations (PEG-4L) are recommended in inflammatory bowel disease (IBD) patients for colonoscopy. However, low-volume preparations (≤ 2 L of active volume) are often used in clinical practice. The aim of the study was to evaluate efficacy, tolerability and safety of the various bowel preparations in IBD, including low-volume preparations. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ecco-jcc/jjz040DOI Listing
February 2019

Trauma on a Recently Augmented Breast as a Trigger for Mondor's Disease.

Aesthetic Plast Surg 2019 Feb 19. Epub 2019 Feb 19.

Adella Aesthetic, 15G, Tintyava Str., 1172, Sofia, Bulgaria.

Mondor's disease is the eponym used to describe a self-limited phlebitis or thrombophlebitis of the superficial veins localized mainly on the thoracoabdominal area of the human body. Its clinical manifestation includes painful superficial cords causing skin retraction. This medical condition could be idiopathic, iatrogenic or a manifestation of underlying pathology such as breast cancer and seems to be more common than has been previously thought. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00266-019-01331-7DOI Listing
February 2019

Invasive pulmonary aspergillosis in cirrhotic patients: analysis of a 10-year clinical experience.

Ann Intensive Care 2019 Feb 18;9(1):31. Epub 2019 Feb 18.

Ecole Nationale Vétérinaire d'Alfort (ENVA), Faculté de Médecine de Créteil, EA Dynamyc Université Paris-Est Créteil (UPEC), 8 rue du Général Sarrail, 94010, Créteil, France.

Background: Cirrhosis is not recognised as one of the main risk factors of invasive pulmonary aspergillosis (IPA), although its prevalence is increasing. The aim of our study was to identify factors for IPA in such patients with a positive Aspergillus sp. culture in respiratory samples and to evaluate its impact on outcome. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13613-019-0502-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379500PMC
February 2019