Dermatol Surg 2021 Feb 8. Epub 2021 Feb 8.
Birmingham Medical School, University of Birmingham, Birmingham, United Kingdom; Department of Dermatology, Aalborg University Hospital, Aalborg, Denmark; Vernova Healthcare CIC, Macclesfield, United Kingdom; Dermatological Surgery and Laser Unit, St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Background: 5-fluorouracil (5-FU) is widely used for treatment of malignant and premalignant skin cancers; however, its use in other common cutaneous conditions has been less widely reported.
Objective: We investigated the off-label uses of 5-FU beyond malignant and premalignant skin disease.
Methods: We conducted a literature review searching multiple databases to evaluate the evidence for the off-label uses of 5-FU. Read More