Search Our Scientific Publications & Authors

J Clin Med 2022 Jun 14;11(12). Epub 2022 Jun 14.

Department of Dermatology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.

According to previous studies, the increased risk of cutaneous infectious disorders in patients with atopic dermatitis (AD) is related to impaired epidermal function, abnormal systemic immune function, and lower antimicrobial peptides. In this study, we analyzed the association between AD and cutaneous infectious disorders in the real world using sequential pattern mining (SPM). We analyzed National Health Insurance data from 2010-2013 using SPM to identify comorbid cutaneous infectious diseases and the onset durations of comorbidities. Read More

Skin Res Technol 2022 Jun 21. Epub 2022 Jun 21.

Department of Dermatology, Tianjin Children's Hospital, Tianjin, China.

Background: Molluscum contagiosum (MC), milia, keratosis pilaris (KP), verruca plana (VP), seborrheic keratosis (SK), and juvenile xanthogranuloma (JXG) are common papule dermatoses on the face of children that have a similar appearance. In vivo evaluation of facial papule dermatoses with reflectance confocal microscopy (RCM) is helpful in the diagnosis of these ambiguous lesions in children. The purpose of this study was to clarify the RCM characteristics of MC, milia, KP, VP, SK, and JXG and explore the clinical application value of RCM for these common facial papule dermatoses. Read More

J Cutan Aesthet Surg 2022 Jan-Mar;15(1):65-70

Department of Dermatology, Venereology & Leprosy, RajaRajeswari Medical College & Hospital, Bengaluru, Karnataka, India.

Context: Molluscum contagiosum (MC) is a common viral cutaneous infection. Despite multiple treatment options, there is no definitive treatment. In some cases, the lesions are severe, recurrent, and cosmetically odd. Read More

Dermatol Pract Concept 2022 May 1;12(2):e2022055. Epub 2022 Apr 1.

Department of Pathology, AIIMS, Bhubaneswar, India.

Front Pharmacol 2022 25;13:868461. Epub 2022 Apr 25.

Department of Pharmaceutical Biology, Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia.

While the chemical composition of vegetable butters and oils has been studied in detail, there is limited knowledge about their mechanisms of action after application on the skin. To understand their dermal effects better, 27 clinical studies evaluating 17 vegetable oils (almond, argan, avocado, borage, coconut, evening primrose, kukui, marula, mustard, neem, olive, rapeseed, sacha inchi, safflower, shea butter, soybean and sunflower oils) were reviewed in this research. The reviewed studies focused on non-affected skin, infant skin, psoriasis, xerosis, UVB-induced erythema, atopic dermatitis, , tungiasis, scars, striae and striae gravidarum. Read More

Actas Dermosifiliogr 2022 Feb 19. Epub 2022 Feb 19.

Department of Dermatology, Hospital General Universitario de Valencia, Valencia, Spain.

Contact Dermatitis 2022 May 3. Epub 2022 May 3.

Dermatology Department, Hospital Universitario San Cecilio, Granada, Spain.

SAGE Open Med Case Rep 2022 22;10:2050313X221086100. Epub 2022 Mar 22.

Department of Dermatology, The First Hospital of Hebei Medical University, Shijiazhuang, P.R. China.

A 24-year-old male presented with asymptomatic penile papules for 1 month. Dermatology examination showed pink, soft papules on the ventral side of the penis, with a clear boundary and rough surface, and papillary hyperplasia could be seen. Dermoscopy revealed multiple finger-like projections without vessels in the center of the lesion under polarized light, and linear and crown-like vessels could be seen at the edge of the lesion. Read More

Medicina (Kaunas) 2022 Feb 23;58(3). Epub 2022 Feb 23.

Department of Dermatology, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Since ancient times, people have tattooed their skin for various reasons. In the past, tattoos were associated with low social status; nowadays, tattoos are very popular and are considered a form of art. However, tattoos are associated with various clinical problems, including immune reactions, inflammatory disorders, infections, and even skin cancer. Read More

Int J STD AIDS 2022 Apr 21;33(5):422-432. Epub 2022 Mar 21.

GUM/HIV Medicine, 4954Central and North West London NHS Foundation Trust, London, UK.

This guideline offers recommendations on diagnosis, treatment regimens and health promotion principles needed for the effective management of genital molluscum, including management of the initial presentation and recurrences. The Primary focus of the guideline is on infection which affects the genital area and has a sexual mode of transmission. This is an update to the guideline previously published in this journal in 2014. Read More

An Bras Dermatol 2022 May-Jun;97(3):358-361. Epub 2022 Mar 17.

Department of Dermatology, Hospital Universitario Puerta De Hierro, Majadahonda, Madrid, Spain.

Atopic dermatitis predisposes to skin infections, and on the other hand, some therapies used for atopic dermatitis may worsen viral infections whose lesions may be more diffuse and resistant to treatment. The authors present a patient with severe atopic dermatitis and disseminated molluscum contagiosum infection. The molluscum contagiosum did not clear with topical treatment, and it worsened her atopic dermatitis even more, so the authors started treatment with dupilumab. Read More

J Am Acad Dermatol 2022 Mar 15. Epub 2022 Mar 15.

Department of Skin & Venereal Disease, Dr Sampurnanand Medical College, Jodhpur, Rajasthan, India.

J Pediatr Ophthalmol Strabismus 2022 Mar 11:1-5. Epub 2022 Mar 11.

Purpose: To report the relative incidence of excised pediatric eyelid lesions and describe the correlation between the clinical and pathology diagnosis.

Methods: This was a retrospective analysis of 137 consecutive pathology-confirmed eyelid lesions excised at a U.S. Read More

Scand J Immunol 2022 05 9;95(5):e13154. Epub 2022 Mar 9.

Department of Immunology, Bai Jerbai Wadia Hospital for Children, Mumbai, India.

Mult Scler Relat Disord 2022 Feb 22;58:103419. Epub 2021 Nov 22.

Department of Neurology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA. Electronic address:

Fingolimod treatment has been associated with opportunistic infections, most notably PML and cryptococcal meningitis. There are rare reports of other infections like molluscum contagiosum which are typically associated with impaired cellular immunity as seen in AIDS. Upon review of our multiple sclerosis patient database, we identified eight patients undergoing fingolimod treatment who developed molluscum contagiosum infections. Read More

Biomedicines 2022 Jan 22;10(2). Epub 2022 Jan 22.

Biodesign Center for Immunotherapy, Vaccines and Virotherapy, Arizona State University, Tempe, AZ 85281, USA.

Poxviridae have developed a plethora of strategies to evade innate and adaptive immunity. In this review, we focused on the vaccinia virus E3 protein, encoded by the gene. E3 is present within the subfamily (with the exception of the avipoxviruses and molluscum contagiosum virus) and displays pleiotropic effects on the innate immune system. Read More

BMC Ophthalmol 2022 Feb 21;22(1):83. Epub 2022 Feb 21.

Department of Ophthalmology, Faculty of Medicine Graduate School of Medicine, Hokkaido University, 7-chome, Kita 15 West, Kita-ku, Sapporo, 060-8638, Japan.

Background: Molluscum contagiosum, a pox virus infection, is likely to occur in the eyelid skin; however, corneal involvements by molluscum lesions are extremely rare. We report a case of molluscum contagiosum arising in the corneal limbus in an untreated AIDS patient, together with anterior segment optical coherence tomography (OCT) findings and histopathology of the excised tumor.

Case Presentation: A 46-year-old man with AIDS was referred to our department for the management of an ocular lesion. Read More

Eur J Case Rep Intern Med 2022 11;9(1):003115. Epub 2022 Jan 11.

Division of Infectious Diseases, Dept. of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Paradoxical immune reconstitution inflammatory syndrome (IRIS) in human immunodeficiency virus (HIV)-positive patients initiating antiretroviral treatment (ART) is caused by restored immunity to specific antigens, resulting in worsening of a pre-existing infection. Molluscum contagiosum (MC) is commonly noted in HIV-positive individuals but ART alone is usually sufficient to bring about resolution. We present a rare case of severe MC-IRIS that worsened despite immune reconstitution. Read More

N Engl J Med 2022 Feb;386(6):582

SUNY Downstate Medical Center, Brooklyn, NY

Am J Ophthalmol Case Rep 2022 Mar 22;25:101335. Epub 2022 Jan 22.

Department of Ophthalmology, University of Washington, Seattle, WA, USA.

Purpose: Periocular molluscum contagiosum can cause a chronic secondary follicular conjunctivitis or keratoconjunctivitis that rarely leads to corneal scarring and visual impairment. We describe two cases of follicular conjunctivitis due to periocular molluscum contagiosum that were successfully treated with topical adapalene 0.1%. Read More

Cureus 2021 Dec 28;13(12):e20780. Epub 2021 Dec 28.

Dermatology, University of California, Davis Medical Center, Sacramento, USA.

Molluscum contagiosum and scabies are contagious conditions that can be acquired by incidental casual contact of a disease-free individual with an infected person. However, both the viral infection and the mite infestation can be transmitted sexually from the infected person to the unsuspecting recipient partner. A 20-year-old man without any infectious diseases acquired not only molluscum contagiosum but also scabies after a single sexual encounter with a female partner; hence, he developed two sexually transmitted diseases after one sexual episode: two for one. Read More

J Dermatol 2022 05 17;49(5):e171-e172. Epub 2022 Jan 17.

Department of Dermatology, Teradamanju Hospital, Kishiwada, Japan.

Sports Health 2022 Jan 17:19417381211065026. Epub 2022 Jan 17.

Department of Dermatology, Mayo Clinic, Jacksonville, Florida.

Context: Athletes are a unique group of patients whose activities, particularly in high-contact sports such as wrestling and football, place them at high risk of developing skin conditions. The correct diagnosis of sports dermatoses requires familiarity with their clinical characteristics. It is critical that primary care physicians recognize the most common skin disorders to provide prompt treatment and prevent transmission. Read More

Pediatr Ann 2022 Jan 1;51(1):e2-e5. Epub 2022 Jan 1.

The skin is the largest organ in the human body, and it acts as the barrier between the world and our bodies. As such, it is constantly being exposed to infections, irritants, and allergens. Approximately one-third of primary care visits involve at least one skin complaint. Read More

J Eur Acad Dermatol Venereol 2022 05 27;36(5):e335-e337. Epub 2022 Jan 27.

Dermatology Unit University of Campania, Naples, Italy.

J Clin Aesthet Dermatol 2021 Oct;14(10):42-47

Dr. Eichenfield is with Rady Children's Hospital and the University of California, San Diego, Medical School in San Diego, California.

Trial Registration: >ClinicalTrials.gov identifier nos. NCT03377790 (for CAMP-1) and NCT03377803 (for CAMP-2). Read More

Dermatology 2021 Dec 30:1-8. Epub 2021 Dec 30.

Department of Dermatology, Venereology and Allergology, Faculty of Medicine, Medical University of Gdańsk, Gdańsk, Poland.

Background: The frequency of tattoos varies from 10% to 30% across the population worldwide. The growing popularity of tattooing increases the number of cutaneous reactions connected with this procedure. As we have not found any previous studies in the literature concerning tattoo complications in Poland and other Eastern European countries, we believe this to be the first study of this kind. Read More

PLoS Pathog 2021 12 28;17(12):e1010177. Epub 2021 Dec 28.

Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America.

The extracellular virion (EV) form of Orthopoxviruses is required for cell-to-cell spread and pathogenesis, and is the target of neutralizing antibodies in the protective immune response. EV have a double envelope that contains several unique proteins that are involved in its intracellular envelopment and/or subsequent infectivity. One of these, F13, is involved in both EV formation and infectivity. Read More

Pathogens 2021 Dec 20;10(12). Epub 2021 Dec 20.

Poxvirus and Rabies Branch, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.

Trends associated with codon usage in molluscum contagiosum virus (MCV) and factors governing the evolution of codon usage have not been investigated so far. In this study, attempts were made to decipher the codon usage trends and discover the major evolutionary forces that influence the patterns of codon usage in MCV with special reference to sub-types 1 and 2, MCV-1 and MCV-2, respectively. Three hypotheses were tested: (1) codon usage patterns of MCV-1 and MCV-2 are identical; (2) SCUB (synonymous codon usage bias) patterns of MCV-1 and MCV-2 slightly deviate from that of human host to avoid affecting the fitness of host; and (3) translational selection predominantly shapes the SCUB of MCV-1 and MCV-2. Read More

Indian J Ophthalmol 2022 Jan;70(1):43-50

Orbit, Oculoplasty, Reconstructive and Aesthetic Services, Sankara Nethralaya, Medical Research Foundation, Chennai, Tamil Nadu, India.

Purpose: : To study the epidemiological pattern and diagnostic accuracy of histopathologically proven eyelid lesions over a period of two decades.

Methods: : A retrospective study of all histopathologically proven eyelid lesions from April 1996 to March 2016 was conducted. The lesions were broadly categorized as benign or malignant. Read More