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BMJ Case Rep 2021 Jun 10;14(6). Epub 2021 Jun 10.

Oncology, Highland Hospital w UCSF affiliation, Oakland, California, USA.

Molluscum contagiosum (MC) is a viral skin infection seen in children, sexually active adults and immunocompromised populations. It is usually a self-limiting illness that typically spontaneously resolves without therapeutic intervention. However, when the papules are extensive or refractory causing complications or aesthetic issues, multiple treatment modalities exist to relieve symptoms, limit spread and decrease the social stigma associated with visible lesions. Read More

Actas Dermosifiliogr 2021 May 28. Epub 2021 May 28.

Unidad de Investigación. Fundación Piel Sana AEDV, Madrid, España.

Background And Objective: Predominantly sexually transmitted infections (PSTIs) and infestations and other anogenital dermatoses are covered in the training of specialists in dermatology and venereology in Spain. This study aimed to analyze the proportion of the dermatology caseload these diseases account for within the Spanish national health service and private practices.

Material And Methods: Observational cross-sectional study of 2 periods. Read More

Ital J Dermatol Venerol 2021 May 28. Epub 2021 May 28.

Department of Health Sciences, University Magna Graecia of Catanzaro, Catanzaro, Italy.

Sex Transm Infect 2021 May 26. Epub 2021 May 26.

Guy's and St Thomas' NHS Foundation Trust, London, UK.

Actas Dermosifiliogr 2021 May 21. Epub 2021 May 21.

Servicio de Anatomía Patológica. Complejo Hospitalario Universitario de Ferrol. Xerencia de Xestión Integrada de Ferrol. SERGAS. Ferrol, A Coruña, España.

J Cutan Aesthet Surg 2020 Oct-Dec;13(4):357-360

Department of DVL, GSL Medical College, Rajahmahendravaram, Andhra Pradesh, India.

Background: Cosmetic procedures are on the rise and practiced by all age groups, especially by teenagers. These procedures enhance the individual appearance and confidence levels, but they are not without side effects.

Aims And Objectives: The aim of this study was to evaluate the side effects occurring after various parlor procedures such as facials, threading, waxing, and laser hair reduction. Read More

Acta Dermatovenerol Croat 2020 Dec;28(7):233-235

Martyna Sławińska MD, PhD, Department of Dermatology, Venereology and Allergology Medical University of Gdańsk, Smoluchowskiego 17 Street, 80-214 Gdańsk;

Giant molluscum contagiosum (MC) is a peculiar variant of the disease with the presence of multiple or single lesions larger than 5 mm. In contrast to typical molluscum contagiosum, dermoscopic features of giant lesions have been poorly described, and none of the reports included multiple giant lesions in an immunocompromised patient. We present a patient with acquired immunodeficiency syndrome diagnosed with multiple giant molluscum contagiosum along with the dermoscopic features of this entity. Read More

Indian J Sex Transm Dis AIDS 2020 Jul-Dec;41(2):162-168. Epub 2020 Jul 31.

Department of Dermatology, B. J. Medical College, Ahmedabad, Gujarat, India.

Context: Sexually transmitted infections (STIs) have a well-established synergistic relationship with human immunodeficiency virus (HIV) infection. Coinfection with HIV and STI can increase the probability of HIV transmission to an uninfected partner by increasing HIV concentrations in genital lesions, genital secretions, or both. Concurrent HIV infection alters the natural history of the classic STIs. Read More

J Infect Dev Ctries 2021 Mar 7;15(2):297-300. Epub 2021 Mar 7.

Infectious Diseases Unit, Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy.

Introduction: Ethnical segregation and migration influence sexual health. Differences in sexual networks and the risk of sexually transmitted diseases (STDs) between racial/ethnic minorities and the native population have been described in the literature.

Methodology: We collected data on sexual behavior and physical examination. Read More

J Dermatolog Treat 2021 Mar 5:1-21. Epub 2021 Mar 5.

Department of Dermatology, Soonchunhyang University Hospital, Seoul, South Korea.

Background: Molluscum contagiosum (MC) is a self-limited cutaneous viral infection. Topical 10% potassium hydroxide (KOH) has been used for treating MC. However, it remains unclear whether it is beneficial or not to apply topical 10% KOH for treating MC. Read More

J Am Acad Dermatol 2021 Jun 25;84(6):1800. Epub 2021 Feb 25.

Am J Clin Dermatol 2021 Mar 18;22(2):257-265. Epub 2021 Feb 18.

Verrica Pharmaceuticals Inc., West Chester, PA, USA.

Background: Compounded cantharidin has been used for decades to treat molluscum contagiosum but lacks rigorous clinical evidence to support its safety and efficacy. VP-102 is a shelf-stable drug-device combination product that contains topical cantharidin (0.7% weight/volume [w/v]) and is being evaluated for the treatment of molluscum. Read More

Dermatol Surg 2021 Feb 8. Epub 2021 Feb 8.

Birmingham Medical School, University of Birmingham, Birmingham, United Kingdom; Department of Dermatology, Aalborg University Hospital, Aalborg, Denmark; Vernova Healthcare CIC, Macclesfield, United Kingdom; Dermatological Surgery and Laser Unit, St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.

Background: 5-fluorouracil (5-FU) is widely used for treatment of malignant and premalignant skin cancers; however, its use in other common cutaneous conditions has been less widely reported.

Objective: We investigated the off-label uses of 5-FU beyond malignant and premalignant skin disease.

Methods: We conducted a literature review searching multiple databases to evaluate the evidence for the off-label uses of 5-FU. Read More

Dermatol Ther 2021 Mar 8;34(2):e14823. Epub 2021 Feb 8.

Department of Health Sciences, University of Eastern Piedmont, Novara, Italy.

During COVID-19 pandemic, wearing masks for prevention became mandatory but evidence suggest that is also detrimental for skin. Although facial dermatoses due to masks increase in both healthcare workers and general population, a pathogenetic hypothesis remains still elusive. We aimed to evaluate the prevalence of dermatological consultations due to Koebner triggered dermatoses In this prospective, multicenter, real life study carried out in Italy from March 11th to December 11th 2020 during COVID-19 pandemics, dermatological consultations (in-person and telemedicine) to study the prevalence of Koebner (KB) phenomenon due to masks were evaluated. Read More

Zhongguo Dang Dai Er Ke Za Zhi 2021 Jan;23(1):98-102

Department of Dermatology, Hunan Children's Hospital, Changsha 410007, China.

A girl, aged 22 months, attended the hospital due to recurrent vulvar rashes for more than half a year. Skin biopsy showed Langerhans cell histiocytosis, and evaluation of systemic conditions showed no systemic involvement. Therefore, the girl was diagnosed with Langerhans cell histiocytosis (skin type). Read More

Microbiol Resour Announc 2021 01 7;10(1). Epub 2021 Jan 7.

Department of Physiology, Anatomy and Microbiology, School of Life Sciences, La Trobe University, Bundoora, VIC, Australia.

The complete genome sequence of molluscum contagiosum virus 1 (MOCV1) isolate NT2017 was sequenced from a tissue sample from an Australian woman. The genome consisted of 185,655 bp encoding 169 predicted open reading frames. Phylogenetically, isolate NT2017 was most closely related to an MOCV1 strain from Slovenia. Read More

J Drugs Dermatol 2021 01;20(1):70-75

Background: This Phase 2, open-label study evaluated the safety, efficacy, systemic exposure, and impact on quality of life (QoL) with treatment using VP-102, a drug-device combination containing cantharidin (0.7% w/v) in subjects with molluscum contagiosum (MC).

Study Design: Pediatric subjects with MC (2–15 years of age) were eligible to enroll in this 12-week study. Read More

Adv Clin Exp Med 2020 Dec;29(12):1491-1495

Institute of Health Sciences, University of Opole, Poland.

Although the benefits of practicing sports are unquestionable, it can contribute to the spread of skin diseases. Mechanical trauma, exposure to environmental and infectious agents, and contact with the skin of other athletes increase the chances of getting an infection. In contact sports, skin infections are responsible for up to 20% of lost training and competition time. Read More

Indian J Med Res 2020 10;152(4):432-433

Department of Ophthalmology, Lady Hardinge Medical College, New Delhi 110 001, India.

Emerg Infect Dis 2021 01;27(1):205-213

Central nervous system (CNS) infection is a serious neurologic condition, although the etiology remains unknown in >50% of patients. We used metagenomic next-generation sequencing to detect viruses in 204 cerebrospinal fluid (CSF) samples from patients with acute CNS infection who were enrolled from Vietnam hospitals during 2012-2016. We detected 8 viral species in 107/204 (52. Read More

Actas Dermosifiliogr (Engl Ed) 2021 May 31;112(5):481-483. Epub 2021 Jan 31.

Hospital y Escuela de Medicina de RKDF, Bhopal, India.

An Bras Dermatol 2021 Jan-Feb;96(1):68-71. Epub 2020 Nov 16.

Department of Dermatology, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

Rosettes are small white structures visible with polarized light dermoscopy, whose exact morphological correlation is not yet defined. These small shiny structures are found in several conditions such as scarring, dermatofibroma, molluscum contagiosum, squamous cell carcinoma, basal cell carcinoma, melanoma, melanocytic nevus, discoid lupus erythematosus, and papulopustular rosacea. In this novel report, the authors describe the presence of rosettes in a T-cell pseudolymphoma lesion. Read More

Dermatol Ther 2021 01 9;34(1):e14615. Epub 2020 Dec 9.

Department of Dermatology, Venereology & Leprology, Teerthanker Mahaveer University Medical College & Research Centre, Moradabad, India.

Molluscum contagiosum (MC) is a mucocutaneous viral infection, often self-limiting but untreated lesions can often last for 2 months to 2 years. Previously intralesional measles, mumps, and rubella (MMR) vaccine has been tried for the treatment of warts but no studies exist of its use in MC. We report our experience with intralesional MMR in 22 patients of MC. Read More

Dermatol Ther 2021 01 10;34(1):e14635. Epub 2020 Dec 10.

Department of Dermatology, Lozano Blesa University Clinical Hospital of Zaragoza, Zaragoza, Spain.

JAMA 2020 Nov;324(20):2020

Cancers (Basel) 2020 Oct 26;12(11). Epub 2020 Oct 26.

University Clinic for Hematology, Oncology, Hemostaseology and Palliative Care Johannes Wesling Medical Center Minden, UKRUB, University of Bochum, Hans-Nolte-Straße 1, D-32429 Minden, Germany.

Ruxolitinib (RUX), a JAK1/JAK2 inhibitor, is approved for second-line therapy in patients with polycythemia vera (PV) who are resistant or intolerant to hydroxyurea. Due to the immunomodulatory and immunosuppressive effect of RUX, there is an increased susceptibility to infections. However, an increased risk of infection is inherent to even untreated myeloproliferative neoplasms (MPN). Read More

G Ital Dermatol Venereol 2020 Oct 16. Epub 2020 Oct 16.

Dermatology Unit, University of Campania, Naples, Italy.

J Am Acad Dermatol 2021 Feb 13;84(2):e113. Epub 2020 Oct 13.

Kaiser Permanente, San Francisco, California. Electronic address:

Dermatol Online J 2020 Sep 15;26(9). Epub 2020 Sep 15.

Dermatology Department. Araba University Hospital. Vitoria-Gasteiz.

Discrete papular mucinosis is a rare variant of primary cutaneous mucinosis. Involvement of genitalia is extremely rare and can mimic molluscum contagiosum. We report the second case of a papular mucinosis with an exclusive genital involvement. Read More

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2020 Aug;45(8):988-993

Department of Dermatology, Third Xiangya Hospital, Central South University, Changsha 410043, China.

Objectives: Reflection confocal microscopy (RCM) is commonly used to assist in the diagnosis of skin diseases. RCM has been found to be useful in the diagnosis of genital warts. The characteristics of genital warts under RCM are not specific. Read More