Transl Cancer Res 2021 Jun;10(6):3090-3110
Department of Health Sciences, University "Magna Graecia" of Catanzaro, viale Europa, Catanzaro, Italy.
Head and neck squamous cell carcinoma (HNSCC) are referred to a group of heterogeneous cancers that include structures of aerodigestive tract such as oral and nasal cavity, salivary glands, oropharynx, pharynx, larynx, paranasal sinuses, and local lymph nodes. HNSCC is characterized by frequent alterations of several genes such as , , , , and as well as copy number increase in , , and . These genomic alterations play a role in terms of resistance to chemotherapy, molecular targeted therapy, and prediction of patient outcome. Read More