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    1 OF 11

    Economic assessment of actual prescription of drugs for treatment of atopic dermatitis: Differences between dermatology and pediatrics in large-scale receipt data.
    J Dermatol 2017 Nov 23. Epub 2017 Nov 23.
    Department of Bio-Environmental Response, Dermatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
    Using large-scale receipt data, we analyzed the differences in the prescription of drugs and their costs between dermatology and pediatrics in the treatment of atopic dermatitis (AD) in children. Between August 2010 and July 2011, 50 706 patients were diagnosed as having AD, and the data of 21 075 (15 257 dermatology, 5818 pediatric) patients aged 0-14 years were included in this study. The use of classes I (strongest), II (very strong), and III (strong) topical corticosteroids and tacrolimus was significantly higher in dermatology than in pediatrics (class I, 2. Read More

    The pH of the main Brazilian commercial moisturizers and liquid soaps: considerations on the repair of the skin barrier.
    An Bras Dermatol 2017 Sep-Oct;92(5):736-738
    Department of Dermatology of Medical School of Botucatu - Universidade Estadual Paulista "Júlio de Mesquita Filho" (FMB-UNESP) - Botucatu (SP), Brazil.
    The pH of the skin is slightly acidic (4.6 to 5.8) which is important for appropriate antibacterial, antifungal, constitution of barrier function, as well as structuring and maturation of the stratum corneum. Read More

    Management of Plantar KeratodermasLessons from Pachyonychia Congenita.
    J Am Podiatr Med Assoc 2017 Sep;107(5):428-435
    Plantar keratodermas can arise due to a variety of genetically inherited mutations. The need to distinguish between different plantar keratoderma disorders is becoming increasingly apparent because there is evidence that they do not respond identically to treatment. Diagnosis can be aided by observation of other clinical manifestations, such as palmar keratoderma, more widespread hyperkeratosis of the epidermis, hair and nail dystrophies, or erythroderma. Read More

    Non-Prescription Treatment Options.
    Adv Exp Med Biol 2017 ;1027:121-137
    Department of Dermatology, Emory School of Medicine, Atlanta, GA, USA.
    The pathogenesis of atopic dermatitis (AD) is complex and multifactorial. However, recent advancements in the genetics and pathophysiology of AD suggest that epidermal barrier dysfunction is paramount in the development and progression of the condition (Boguniewicz and Leung, Immunol Rev 242(1):233-246, 2011). In addition to standard therapy for AD, there are a plethora of non-prescription treatment modalities which may be employed. Read More

    Efficacy of the combined use of a mild foaming cleanser and moisturizer for the care of infant skin.
    Clin Cosmet Investig Dermatol 2017 3;10:393-401. Epub 2017 Oct 3.
    Department of Dermatology, Kanagawa Children's Medical Center, Yokohama, Japan.
    Objective: Despite the application of skin care treatments, many infants have skin problems such as dryness and erythema. We proposed a new combination skin care for infants which consisted of a foaming cleanser with lower surfactant activity and moisturizers that contained pseudo-ceramide.

    Subjects And Methods: A total of 50 infants (age: 3-24 months) with insignificant levels of dry skin were enrolled in this usage trial. Read More

    Ospemifene: A Novel Option for the Treatment of Vulvovaginal Atrophy.
    J Menopausal Med 2017 Aug 31;23(2):79-84. Epub 2017 Aug 31.
    Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea.
    Ospemifene-a third-generation selective estrogen receptor modulator approved by the Food and Drug Administration in 2013-is an oral medication for the treatment of dyspareunia. In postmenopausal women with vulvovaginal atrophy, ospemifene significantly improves the structure and pH levels of the vagina, reducing dyspareunia. It is available as a 60-mg tablet; hence, women who may have had prior difficulty with vaginal administration or on-demand use of nonprescription lubricants and moisturizers would likely prefer this form of treatment. Read More

    Dermopathy associated with cetuximab and panitumumab: investigation of the usefulness of moisturizers in its management.
    Clin Cosmet Investig Dermatol 2017 11;10:353-361. Epub 2017 Sep 11.
    Department of Geriatric and Environmental Dermatology.
    Aims: Limited data regarding the objective evaluation of skin exsiccation caused by epidermal growth factor receptor (EGFR) inhibitors exist. Objective indices were applied to evaluate the usefulness of a moisturizer against skin exsiccation associated with the use of EGFR inhibitors in cancer patients.

    Patients And Methods: Patients with either colorectal or head and neck cancer treated with either cetuximab or panitumumab were randomly assigned 1:2 to the prophylactic-treatment arm, where participants received prophylactical moisturizer treatment (heparinoid preparation, Hirudoid(®)), or to the symptomatic-treatment arm, where moisturizer was applied after the onset of cutaneous symptoms. Read More

    Atopic dermatitis: skin care and topical therapies.
    Semin Cutan Med Surg 2017 Sep;36(3):104-110
    Division of Pediatric and Adolescent Dermatology, Rady Children's Hospital, San Diego, California, USA.
    Atopic dermatitis (AD) pathogenesis is strongly influenced by Type 2 innate lymphoid cell and T-helper cell type 2 lymphocyte-driven inflammation and skin barrier dysfunction. AD therapies attempt to correct this pathology, and guidelines suggest suggest basics of AD therapy, which include repair of the skin barrier through bathing practices and moisturizers, infection control, and further lifestyle modifications to avoid and reduce AD triggers.While some patients' AD may be controlled using these measures, inflammatory eczema including acute flares and maintenance therapy in more severe patients are treated with topical pharmacologic agents such as topical corticosteroids, topical calcineurin inhibitors, and, more recently, topical PDE-4 inhibitors. Read More

    Consumer Preferences, Product Characteristics, and Potentially Allergenic Ingredients in Best-selling Moisturizers.
    JAMA Dermatol 2017 Nov;153(11):1099-1105
    Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
    Importance: Because moisturizer use is critical for the prevention and treatment of numerous dermatological conditions, patients frequently request product recommendations from dermatologists.

    Objective: To determine the product performance characteristics and ingredients of best-selling moisturizers.

    Design And Setting: This cohort study involved publicly available data of the top 100 best-selling whole-body moisturizing products at 3 major online retailers (Amazon, Target, and Walmart). Read More

    Quantitation of 24-Hour Moisturization by Electrical Measurements of Skin Hydration.
    J Wound Ostomy Continence Nurs 2017 Sep/Oct;44(5):487-491
    R. Randall Wickett, PhD, James L. Winkle College of Pharmacy, Cincinnati, Ohio. Bronson Damjanovic, BS, Coloplast Corporation, Mankato, Minnesota.
    Purpose: The purpose of this study was to quantify the effects of several moisturizers on hydration of the stratum corneum by measuring their effect on electrical conductance over a 24-hour period.

    Design: Double-blind, randomized controlled trial.

    Subjects And Setting: Twenty-five healthy female volunteers aged 18 to 65 years with dry skin on the lower legs and no other known dermatologic pathology participated in the study. Read More

    The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study.
    Clin Cosmet Investig Dermatol 2017 11;10:311-315. Epub 2017 Aug 11.
    Dermatologic Institute Dermig Milan, Milan, Italy.
    Introduction: Moisturizing products are commonly used to improve hydration in skin dryness conditions. However, some topical hydrating products could have negative effects on skin barrier function. In addition, hydrating effects of moisturizers are not commonly evaluated up to 24 hours after a single application. Read More

    Emu oil-based lotion effects on neonatal skin barrier during transition from intrauterine to extrauterine life.
    Clin Cosmet Investig Dermatol 2017 10;10:299-303. Epub 2017 Aug 10.
    Division of Perinatal Medicine, Policlinico Abano Terme, Abano Terme.
    Both appropriate hydration and skin surface pH are fundamental in preventing baby skin barrier damage during transition from intrauterine to extrauterine life. However, effects of topical moisturizers on neonatal stratum corneum temperature, pH, hydration, and elasticity have not been scientifically evaluated in vivo. We checked 31 full-term breastfeeding neonates by non-invasive bioengineering method, which is able to evaluate the basal skin barrier (left heel), and assessed at 6±1 hours after birth, and at 1 and 24 hours after emu oil-based topical treatment. Read More

    Acidic oral moisturizers with pH below 6.7 may be harmful to teeth depending on formulation: a short report.
    Clin Cosmet Investig Dent 2017 3;9:81-83. Epub 2017 Aug 3.
    Department of Operative Dentistry, Faculty of Odontology, University of Iceland and Private Practice, Reykjavic, Iceland.
    Xerostomia affects 30% of the population and manifests as a side effect of medications, systemic diseases, or cancer therapy. Oral moisturizers are prescribed to overcome the ailments of dry mouth and its symptoms. It is imperative that these products help to restore hyposalivation and that they do not present any secondary effect that can harm oral health. Read More

    Fragility of epidermis: acne and post-procedure lesional skin.
    J Eur Acad Dermatol Venereol 2017 Sep;31 Suppl 6:3-18
    A-DERMA, Pierre Fabre Dermo-Cosmétique, Lavaur, France.
    'Fragile skin', or skin with lower resistance to aggressors, can be broadly classified into four causal categories: constitutional (age-dependent or associated with specific vulnerable locations on the body, e.g. eyelids), pathological (related to disease), circumstantial (related to environmental or internal factors, e. Read More

    Use of moisturizers among Danish atopic dermatitis patients-which perceived product characteristics associate with long-term adherence?
    J Dermatolog Treat 2017 Aug 18:1-7. Epub 2017 Aug 18.
    b Department of Dermatology , Zealand University Hospital , Roskilde , Denmark.
    Purpose: To identify factors perceived as most important regarding choice and continued use of moisturizers for adult patients with AD.

    Method And Materials: Online survey among members of the Atopic eczema society Denmark.

    Results: Among 75 participants, the most commonly tried (89. Read More

    High Staphylococcus epidermidis Colonization and Impaired Permeability Barrier in Facial Seborrheic Dermatitis.
    Chin Med J (Engl) 2017 Jul;130(14):1662-1669
    Department of Dermatology, The First Hospital of China Medical University, Shenyang, Liaoning 110001, China.
    Background: Seborrheic dermatitis (SD) is a common inflammatory skin condition. The etiology is unclear, although overgrowth of Malassezia on the skin has been suggested to cause SD. This study investigated whether colonization with Staphylococcus plays a role in facial SD, which was not well addressed previously. Read More

    Combination of benzoyl peroxide 5% gel with liquid cleanser and moisturizer SPF 30 in acne treatment results in high levels of subject satisfaction, good adherence and favorable tolerability.
    J Dermatolog Treat 2017 Jul 5:1-6. Epub 2017 Jul 5.
    b Galderma R&D , Sophia Antipolis , France.
    Background: Skin care products (cleansers and moisturizers) to complement benzoyl peroxide (BPO) in the treatment of acne may improve treatment tolerability and adherence.

    Objective: Evaluate subject satisfaction after use of BPO 5% gel in combination with liquid cleanser and moisturizer SPF 30.

    Methods: Open-label study including subjects aged ≥12 years with mild-to-moderate facial acne; ClinicalTrials. Read More

    Evaluation of a novel very high sun-protection-factor moisturizer in adults with rosacea-prone sensitive skin.
    Clin Cosmet Investig Dermatol 2017 10;10:211-219. Epub 2017 Jun 10.
    Galderma Research and Development, Egerkingen, Switzerland.
    Background/objective: Rosacea-prone sensitive skin requires high sun-protection factor (SPF) moisturizers. This study evaluated Daylong Extreme SPF 50+ lotion, a novel cream containing five ultraviolet filters, two emollients, and three skin conditioners.

    Subjects And Methods: This was an open-label, single-center study. Read More

    Performance and Tolerability of the Moisturizers Cetaphil(®) and Excipial(®) in Atopic Dermatitis: What is the Evidence Based on Randomized Trials?
    Dermatol Ther (Heidelb) 2017 Sep 9;7(3):331-347. Epub 2017 Jun 9.
    Dutch Association for People with Atopic Dermatitis (VMCE: Vereniging voor Mensen met Constitutioneel Eczeem), Nijkerk, The Netherlands.
    Introduction: Moisturizers play a prominent role in the management of atopic dermatitis by improving the impaired skin barrier function and enhancing skin hydration. Their efficacy was evaluated in a recently published Cochrane Review 'Emollients and moisturizers for eczema'.

    Objective: In the present review, we summarize the performance and safety of Cetaphil(®) and Excipial(®) moisturizing products. Read More

    Novel concepts of prevention and treatment of atopic dermatitis through barrier and immune manipulations with implications for the atopic march.
    J Allergy Clin Immunol 2017 Jun;139(6):1723-1734
    Department of Dermatology and the Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY; Laboratory for Investigative Dermatology, Rockefeller University, New York, NY. Electronic address:
    Skin barrier abnormalities have been suggested to play an essential role in initiation of early atopic dermatitis (AD). Antigen penetration through a compromised barrier likely leads to increased innate immune responses, antigen-presenting cell stimulation, and priming of overt cutaneous disease. In a TH2-promoting environment, T-cell/B-cell interactions occurring in regional lymph nodes lead to excessive IgE switch. Read More

    Sexual health needs and educational intervention preferences for women with cancer.
    Breast Cancer Res Treat 2017 Aug 25;165(1):77-84. Epub 2017 May 25.
    Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
    Purpose: To assess sexual/vaginal health issues and educational intervention preferences in women with a history of breast or gynecologic cancer.

    Methods: Patients/survivors completed a cross-sectional survey at their outpatient visits. Main outcome measures were sexual dysfunction prevalence, type of sexual/vaginal issues, awareness of treatments, and preferred intervention modalities. Read More

    Emollients and moisturizers for eczema: abridged Cochrane systematic review including GRADE assessments.
    Br J Dermatol 2017 Apr 22. Epub 2017 Apr 22.
    Dutch Association for People with Atopic Dermatitis (VMCE: Vereniging voor Mensen met Constitutioneel Eczeem), Nijkerk, the Netherlands.
    Eczema is a chronic inflammatory skin disorder with considerable impact on quality of life. Emollients or moisturizers are widely recommended, but are these effective and safe? We searched for randomized controlled trials (RCTs) in the Cochrane Skin Group Specialised Skin Register, CENTRAL in The Cochrane Library, MEDLINE, Embase, LILACS, the GREAT database and five trial registers to December 2015. We included 77 RCTs with 6603 participants. Read More

    An epidemic of allergic contact dermatitis caused by a new allergen, caprylhydroxamic acid, in moisturizers.
    Contact Dermatitis 2017 Sep 19;77(3):159-162. Epub 2017 Apr 19.
    Department of Dermatology and Allergy Centre, Tampere University Hospital, 33520, Tampere, Finland.
    Background: In 2016, dermatologists in Finland suspected contact allergy in several patients using moisturizers under the trade name Apobase®. Following a formulation change, Phenostat™, which is a mixture of phenoxyethanol, caprylhydroxamic acid, and methylpropanediol, was used as a preservative in Apobase® moisturizers in Finland.

    Objectives: To confirm the suspected contact allergy to Apobase® cream, oily cream, and/or lotion, and to identify the specific contact allergen and define its optimal patch test concentration. Read More

    Use of vegetable oils in dermatology: an overview.
    Int J Dermatol 2017 Nov 19;56(11):1080-1086. Epub 2017 Apr 19.
    Department of Dermatology, MAMC and associated LNJP Hospital, New Delhi, India.
    Vegetable oils have been used for a wide variety of purposes since time immemorial; however, their principle use remains as skin moisturizers, especially in neonates and children. Because of their considerable efficacy and a low side effect profile and bearable cost, these oils are hugely popular as moisturizers among the common people in countries such as India. A wide variety of oils have been used, and newer ones are coming up with each passing day. Read More

    [Confluent and reticulated papillomatosis subsiding spontaneously after delivery: Report of one case].
    Rev Med Chil 2016 Nov;144(11):1494-1496
    Family Medicine Department, American University of Beirut Medical Center, Beirut, Lebanon.
    Gougerot and Carteaud confluent and reticulated papillomatosis (CARP) is an uncommon dermatosis characterized by hyperpigmented scaly macules or papillomatous papules coalescing into confluent patches or plaques centrally with a reticular pattern peripherally. We report a 28-year-old woman presenting at 16 weeks of gestation with an itchy rash that was biopsied and turned out to be consistent with CARP. Options for treatment were discussed but the woman refused to take any systemic therapy and used only moisturizers throughout her pregnancy. Read More

    Management of Atopic Dermatitis in Japan.
    J Nippon Med Sch 2017 ;84(1):2-11
    Department of Dermatology, Nippon Medical School.
    The guidelines for the treatment of atopic dermatitis (AD) issued by the Japanese Dermatological Association (JDA), which are basically designed for dermatologists, were first prepared in 2000 and revised in 2016. The guidelines for AD of the Japanese Society of Allergology (JSA), which are basically designed for allergologists, including internists, otorhinolaryngologists, ophthalmologists, and dermatologists, were first prepared in 2009 and revised in 2014. In this article, I review the definition, pathophysiology, etiology, epidemiology, diagnosis, severity classification, examination for diagnosis and severity assessment, and treatments for AD in Japan according to these two guidelines for AD (JDA and JSA). Read More

    Seeking better topical delivery technologies of moisturizing agents for enhanced skin moisturization.
    Expert Opin Drug Deliv 2017 Mar 20:1-15. Epub 2017 Mar 20.
    a College of Pharmacy , Chung-Ang University , Seoul , Republic of Korea.
    Introduction: An adequate hydration level is essential to maintain epidermal barrier functions and normal physiological activities of skin tissues. Diverse moisturizing agents and pharmaceutical formulations for dermal deliveries have thus extensively been investigated. This review comprehensively discusses scientific outcomes of moisturizing agents and pharmaceutical vehicles for skin moisturization, thereby providing insight into designing innovative pharmaceutical formulations for effective skin moisturization. Read More

    Cosmeceuticals for rosacea.
    Clin Dermatol 2017 Mar - Apr;35(2):213-217. Epub 2016 Oct 27.
    Consulting Professor, Department of Dermatology, Duke University School of Medicine, Durham, North Carolina. Electronic address:
    Patients with rosacea present a challenge to the dermatologist, as they typically possess sensitive skin, need facial Demodex and bacterial colonization control, exhibit vasomotor instability, require camouflaging of telangiectatic mats, and desire prescription treatment. Currently available pharmaceuticals are aimed at inflammation reduction, primarily with the use of topical and oral antibiotics. Recently, vasoconstrictor formulations have emerged, but these drugs have only a temporary effect and improve appearance without addressing the underlying cause, which remains largely unknown. Read More

    A pilot randomized trial to prevent sexual dysfunction in postmenopausal breast cancer survivors starting adjuvant aromatase inhibitor therapy.
    J Cancer Surviv 2017 Aug 22;11(4):477-485. Epub 2017 Feb 22.
    Department of Behavioral Science, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
    Purpose: A randomized pilot trial evaluated the hypothesis that early intervention lessens sexual dysfunction in the first year on aromatase inhibitors. A secondary aim was comparing the efficacy of two vaginal moisturizers.

    Methods: Fifty-seven postmenopausal women with early stage breast cancer starting aromatase inhibitors were randomized to three treatment groups. Read More

    Diagnosis and Management of Chronic Pruritus: An Expert Consensus Review.
    Indian J Dermatol 2017 Jan-Feb;62(1):7-17
    Skin Diseases Center, Nashik, Maharashtra, India.
    The aim of this study is to formulate the best clinical practice in the diagnosis and management of chronic pruritus (CP). We searched PubMed, EMBASE, Scopus, Web of Science, and the WHO's regional databases, for studies on "Diagnosis and management of chronic pruritus" from January 1, 2014, to July 31, 2015. We included programmatic reports and hand-searched references of published reviews and articles. Read More

    Multivesicular Emulsion Ceramide-containing Moisturizers: An Evaluation of Their Role in the Management of Common Skin Disorders.
    J Clin Aesthet Dermatol 2016 Dec 1;9(12):26-32. Epub 2016 Dec 1.
    Department of Dermatology, Mount Sinai Hospital, New York, New York.
    Proper stratum corneum function plays a pivotal role in maintenance of skin health, and improper function leads to skin disease. The stratum corneum is comprised of corneocytes surrounded by intercelluar lipids including ceramides, free fatty acids, and cholesterol. Ceramide predominant moisturizers have become a mainstay of treatment of skin disease. Read More

    Characterization and biocompatibility evaluation of cutaneous formulations containing lipid nanoparticles.
    Int J Pharm 2017 Mar 25;519(1-2):373-380. Epub 2017 Jan 25.
    UCIBIO, ReQuimTe, Laboratory of Pharmaceutical Technology/Centre of Research in Pharmaceutical Sciences, Faculty of Pharmacy, Porto University, Porto, Portugal; FP-ENAS (UFP Energy, Environment and Health Research Unit), CEBIMED (Biomedical Research Centre), Faculty of Health Sciences, Fernando Pessoa University, Rua Carlos da Maia, 296, P-4200-150 Porto, Portugal. Electronic address:
    Nanostructured lipid carriers (NLC) are well-known systems that show effectiveness to improve skin hydration, being suggested for cosmetic and dermatological use. Nonetheless, NLC dispersions present low viscosity, which is non-attractive for cutaneous application. To circumvent this drawback, the dispersions can be gelled or incorporated in semisolid systems, increasing the final formulation consistency. Read More

    Efficacy of a Skin Condition-Adapted Solution for Xerosis and Itch Relief Associated With Aging.
    J Drugs Dermatol 2016 Nov;15(11):s91-s94
    In recent decades, the stratum corneum (SC), has been recognized for its multifunctional role in maintaining the homeostasis of the human epidermal barrier. A better understanding of the SC's ability to act as its own biosensor in detecting dysfunction and integrating restorative actions can help identify the origin of certain skin conditions. A more holistic understanding of the morphological changes of the SC during the natural aging process and how it deviates in disease states can help bring about new treatment strategies. Read More

    Exogenous Factors in Skin Barrier Repair.
    J Drugs Dermatol 2016 Nov;15(11):1289-1294
    The stratum corneum (SC) is the skin's outermost layer and serves the primary function of acting as a shield to keep foreign matter out and to essential elements, such as moisture and water, in. Maintenance of this skin barrier is crucial to healthy functioning skin. A damaged or diseased skin barrier is vulnerable to infection, irritants, and allergens. Read More

    The effect of moisturizers or creams on scars: a systematic review protocol.
    JBI Database System Rev Implement Rep 2017 Jan;15(1):15-19
    1The Joanna Briggs Institute, Faculty of Health and Medical Sciences, The University of Adelaide, Australia 2Adult Burn Service, Royal Adelaide Hospital, Adelaide, Australia.
    Review Question/objective: The objectives of the review are to identify the effect of any moisturizers or creams (medicated or unmedicated) on immature scars (linear, keloid or hypertrophic) on any persons of any age. Effects will be assessed by changes in scar activity, changes in the final appearance/cosmesis of the scar, improvements in patient reported features of scars (e.g. Read More

    Role of Pregabalin in Management of Pruritus: A Literature Review.
    J Pharm Pharm Sci 2016 Oct - Dec;19(4):465-474
    Faculty of Pharmacy and Pharmaceutical Sciences, Kerman University of Medical Sciences, Kerman, Iran.
    Pruritus can be one of the distressing symptoms of many dermatologic, systemic, neurologic or psychiatric disorders. In each case, the origin of itch is in the skin and/or the nervous system. Involvement of the nervous system causes neurogenic, psychogenic or neuropathic itch. Read More

    Hormone Therapy and Other Treatments for Symptoms of Menopause.
    Am Fam Physician 2016 Dec;94(11):884-889
    Orlando, FL, USA.
    The results of large clinical trials have led physicians and patients to question the safety of hormone therapy for menopause. In the past, physicians prescribed hormone therapy to improve overall health and prevent cardiac disease, as well as for symptoms of menopause. Combined estrogen/progestogen therapy, but not estrogen alone, increases the risk of breast cancer when used for more than three to five years. Read More

    Cost-effectiveness of Prophylactic Moisturization for Atopic Dermatitis.
    JAMA Pediatr 2017 Feb 6;171(2):e163909. Epub 2017 Feb 6.
    Chicago Integrative Eczema Center, Chicago, Illinois.
    Importance: Emerging evidence suggests that the use of moisturizers on newborns and infants (ie, from birth to 6 months of age) is potentially helpful in preventing the development of atopic dermatitis.

    Objective: To investigate the cost-effectiveness of using a daily moisturizer as prevention against atopic dermatitis among high-risk newborns.

    Design, Setting, And Participants: In a cost-effectiveness analysis, the average cost of total-body moisturization using 7 common moisturizers from birth to 6 months of age was determined for male and female infants. Read More

    Association Between Infertility and Sexual Dysfunction in Men and Women.
    Sex Med Rev 2016 Oct 4;4(4):353-365. Epub 2016 Jun 4.
    Department of Urology, University of Miami-Miller School of Medicine, Miami, FL, USA. Electronic address:
    Introduction: The relation between infertility and sexual dysfunction can be reciprocal. Causes of sexual dysfunction that affect fertility include erectile dysfunction, Peyronie's disease (abnormal penile curvature), low libido, ejaculatory disorders in men, and genito-pelvic pain/penetration disorder (GPPPD) and low sexual desire in women.

    Aim: To review the association between infertility and sexual dysfunction and discuss current management strategies to address sexual disorders in couples with infertility. Read More

    Vaginal and sexual health treatment strategies within a female sexual medicine program for cancer patients and survivors.
    J Cancer Surviv 2017 Apr 21;11(2):274-283. Epub 2016 Nov 21.
    Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.
    Purpose: We sought to evaluate patient adherence and response to simple vaginal and sexual health treatment strategies in female cancer patients receiving treatment at a female sexual medicine and health program and identify improvements of physical symptoms, per patient and clinical evaluation.

    Methods: Evaluability criteria included gynecologic exam at initial visit, at least one follow-up with gynecologic exam within 8 months of initial visit, and all consecutive follow-ups <6 months apart. Demographics, medical information, and clinical assessments from 175 evaluable patients with at least one follow-up from 09/12 to 10/14 were analyzed. Read More

    Effectiveness of interventions for preventing occupational irritant hand dermatitis: a quantitative systematic review protocol.
    JBI Database System Rev Implement Rep 2016 Oct;14(10):72-81
    1The Scottish Centre for Evidence-based, Multi-professional Practice: a Joanna Briggs Institute Centre of Excellence, Aberdeen, United Kingdom 2Robert Gordon University, Aberdeen, United Kingdom 3National Health Service Grampian, Aberdeen, United Kingdom.
    Review Question/objective: The objective of this quantitative systematic review is to identify, appraise and synthesize the best available evidence on the effectiveness of moisturizers, barrier creams, protective gloves, skin protection education and complex interventions (a combination of two or more of the interventions listed) in preventing occupational irritant hand dermatitis (OIHD) in wet workers. These interventions will be compared to an alternative intervention or to usual care (workers regular skin care regime). The specific review question is: "What is the effectiveness of moisturizers, barrier creams, protective gloves, skin protection education and complex interventions in preventing OIHD in wet workers?" Read More

    Rosacea Management.
    Skin Appendage Disord 2016 Sep 18;2(1-2):26-34. Epub 2016 May 18.
    Department of Dermatology, Center for Dermatology Research, Wake Forest School of Medicine, Winston-Salem, N.C., USA.
    Background: Rosacea is a chronic inflammatory skin condition associated with four distinct subtypes: erythematotelangiectatic, papulopustular, phymatous, and ocular.

    Purpose: To review the different kinds of management for all subtypes.

    Methods: We divided rosacea management into three main categories: patient education, skin care, and pharmacological/procedural interventions. Read More

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