5,445 results match your criteria Mohs Micrographic Surgery


No difference in survival for primary cutaneous pleomorphic sarcoma after Mohs micrographic surgery and wide local excision.

J Am Acad Dermatol 2022 Jun 25. Epub 2022 Jun 25.

Department of Dermatology, Brigham and Women's Hospital, Boston, MA; Harvard Medical School, Boston, MA; Dana Farber/Brigham and Women's Cancer Center, Boston, MA. Electronic address:

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Clinical outcomes of high-risk cutaneous squamous cell carcinomas treated with Mohs micrographic surgery alone: an analysis of local recurrence, regional nodal metastases, progression-free survival, and disease-specific death.

J Am Acad Dermatol 2022 Jun 24. Epub 2022 Jun 24.

Zitelli and Brodland Skin Cancer Center, Pittsburgh, PA 15232; University of Pittsburgh Medical Center, Pittsburgh, PA 15232.

Importance: The incidence of cutaneous squamous cell carcinomas (cSCC) continues to increase, and is now predicted that deaths from cSCC will surpass that of melanoma within the next 5 years. Although most cSCCs are successfully treated, there exists an important subset of high-risk tumors that have the highest propensity for local recurrence (LR), nodal metastasis (NM), and disease-specific death (DSD).

Objective: We investigated the clinical outcomes of high-risk cSCCs treated with MMS alone, analyzing LR, NM, DM, and DSD. Read More

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Value of Permanent Pathology for Debulk and Mohs Specimens during Mohs Micrographic Surgery for Cutaneous Squamous Cell Carcinoma: A Retrospective Cohort Study.

J Am Acad Dermatol 2022 Jun 23. Epub 2022 Jun 23.

Department of Dermatology, University of Texas Southwestern Medical Center, 5939 Harry Hines Blvd, 4th Floor, Suite 100, Dallas, 75390-9191.

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Trends in matching into Mohs Micrographic Surgery fellowship among underrepresented minority applicants from 2016 to 2020: a retrospective review study.

Arch Dermatol Res 2022 Jun 25. Epub 2022 Jun 25.

Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.

Disparities in racial diversity in the field of dermatology continue to persist given that dermatology has the second lowest percentage of underrepresented minorities (URM), only second to orthopedic surgery. This study aims to investigate any trends in racial representation of Mohs Micrographic Surgery (MMS) fellowship applicants over a five-year period from 2016 to 2020. Dermatology residency applicant race data were extracted from the San Francisco Match for application seasons 2016-2020 for a retrospective review study. Read More

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In-transit metastasis of cutaneous squamous cell carcinoma: report of two cases.

Acta Dermatovenerol Alp Pannonica Adriat 2022 Jun;31(2):75-77

Department of Dermatology and Venereology, Haydarpaşa Numune Training and Research Hospital, Istanbul, Turkey.

Transit metastases include metastatic foci of the skin and subcutaneous tissue located between the tumor and the nearest regional lymph node. Although transit metastases have been described for malignant melanoma, some cases of transit metastases have also been reported among primary cutaneous non-melanoma cancers. Treatment of patients with in-transit squamous cell carcinoma (SCC) is a multimodal approach for advanced staging imaging and therapy, including Mohs micrographic surgery, adjuvant radiation, and possibly sentinel lymph node biopsy and immunotherapy or chemotherapy. Read More

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Clinical features associated with the invasive component in lentigo maligna of the head and neck: A retrospective study of 175 cases.

Ann Dermatol Venereol 2022 Jun 20. Epub 2022 Jun 20.

Department of Dermatology, CHU, Bordeaux, France; INSERM U1053, Bordeaux Research in Translational Oncology, Université Bordeaux, Bordeaux, France.

Background: Lentigo maligna (LM) can develop into lentigo maligna melanoma (LMM) with risk of metastatic dissemination. LMM may be underestimated on the basis of the initial biopsy. The invasion may affect both the therapeutic options and the prognosis. Read More

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Basal Cell Carcinoma: A Narrative Review on Contemporary Diagnosis and Management.

Oncol Ther 2022 Jun 21. Epub 2022 Jun 21.

Department of Histopathology, University Hospital Dorset NHS Foundation Trust, Bournemouth, UK.

Basal cell carcinoma (BCC) is the most common, accounting for 80-90% of skin cancers. It arises from the basal layer of the epidermis and its appendages. A complex interplay of environmental, phenotypic and genetic variables leads to the development of BCC. Read More

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Second-Intention Healing in Mohs Micrographic Surgery: A Single-Center Academic Experience.

Adv Skin Wound Care 2022 Jul;35(7):375-380

Julián Barrera-Llaurador, MD, is Dermatology Assistant Professor, Department of Dermatology, University of Puerto Rico School of Medicine, San Juan. Osward Y. Carrasquillo, MD, MPH, is Mohs Micrographic Surgery Fellow, Department of Dermatology, University of North Carolina, Chapel Hill. Marely Santiago-Vázquez, MD, is Dermatology Resident, Department of Dermatology, University of Puerto Rico School of Medicine. Valeria J. González-Molina, MD, is Clinical Fellow, Department of Dermatology, HCA Corpus Christi Medical Center-Bay Area, Texas. Sheila M. Valentín-Nogueras, MD, is Mohs Micrographic Surgeon, Director of Dermatologic Surgery, Department of Dermatology, University of Puerto Rico School of Medicine. The authors have disclosed no financial relationships related to this article. Submitted August 18, 2021; accepted in revised form January 10, 2022.

Objective: To describe the trends in second-intention healing (SIH) use at a single Mohs micrographic surgery (MMS) dermatology clinic and assess outcomes and patient satisfaction.

Methods: The authors conducted a single-center, retrospective study of patients who underwent MMS from November 2012 through November 2018. Data obtained for each patient included sex, age, tumor characteristics, number of MMS stages, final defect size, and postoperative complications. Read More

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[Recurrent Darier-Ferrand dermatofibrosarcoma in the abdominal wall: the role of preoperative radiotherapy (case report)].

Pan Afr Med J 2022 22;41:234. Epub 2022 Mar 22.

Service de Radiothérapie, CHU Mohammed VI, Oujda, Maroc.

Dermatofibrosarcoma is a rare cancer, accounting for 0.01% of all cancers. We here report the case of a 44-year-old female patient presenting with the 5 recurrence of locally advanced Darier-Ferrand dermatofibrosarcoma, that progressed on many cycles of neoadjuvant therapy and required emergency radiotherapy with good response. Read More

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Use of Biologic Agents in Extremity Reconstruction.

Semin Plast Surg 2022 Feb 12;36(1):43-47. Epub 2022 Apr 12.

Department of Plastic Surgery, University of Texas Southwestern Medical Center, Dallas, Texas.

Skin and soft tissue defects of the lower extremity present a unique challenge for the reconstructive surgeon. Successful repair of the lower extremity relies not only on strong anatomical knowledge and surgical expertise, but also on careful consideration of the numerous preoperative factors and indications that may alter the patient's response to operative management. While many of these injuries result from burns, avulsive trauma, diabetes, or vascular insufficiencies, a significant portion can be associated with resection of neoplastic pathologies. Read More

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February 2022

Use of Biologic Agents for Lip and Cheek Reconstruction.

Semin Plast Surg 2022 Feb 31;36(1):26-32. Epub 2021 Dec 31.

Department of Plastic Surgery, University of Texas Southwestern Medical Center, Dallas, Texas.

The unique requirements of reconstructing cheek defects, often with its proximity to the mobile elements of the face including the lip and the eyelid, have been met very handily with the directed and thoughtful use of biologic wound healing agents. One of the key advantages of these agents is their ability to provide coverage for the mobile elements of the cheek and the lip in patients with multiple co-morbidities. These agents are successfully used where the standard cheek closure techniques including cervicofacial advancement flap are contraindicated due to its anesthetic requirement. Read More

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February 2022

Use of Biologic Agents in Nasal and Scalp Reconstruction.

Semin Plast Surg 2022 Feb 9;36(1):17-25. Epub 2022 Mar 9.

Department of Plastic Surgery, University of Texas Southwestern Medical Center, Dallas, Texas.

Oncologic reconstruction of the nose and scalp following Mohs micrographic surgery poses a significant challenge for plastic surgeons. While these defects are traditionally reconstructed using primary closure techniques, skin grafts, local flaps, pedicled flaps, and free tissue transfer, the incorporation of biologic healing wound agents such as Integra and Cytal provides patients and surgeons with alterative reconstructive options without additional donor site morbidity. Herein, we review the use of biologic agents used in soft tissue reconstruction of the nose and scalp following Mohs surgery. Read More

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February 2022

Mohs Micrographic Surgery in Squamous Cell Carcinoma of the Nail Unit.

Actas Dermosifiliogr 2022 05 17;113(5):526-528. Epub 2021 Nov 17.

Servicio de Dermatología, Hospital Universitario Fundación Alcorcón, Alcorcón, Madrid, España.

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Dermatology Care in Spanish Public Hospitals: A Mapping Study of Health Care Resources and Medical and Surgical Activity in Dermatology Departments in 2019.

Actas Dermosifiliogr 2022 May 2;113(5):467-480. Epub 2021 Nov 2.

Servicio de Dermatología, Hospital Universitario Virgen de las Nieves, Granada, España; TECe19-Dermatología Clínica y Traslacional, Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, España; Universidad de Granada, Granada, España.

Background And Objective: No recent data on health care resources and medical and surgical activity in Spanish dermatology departments are available in the literature. The aim of this study was to compile this information for 2019.

Material And Methods: Cross-sectional study based on an online survey sent to the heads of dermatology departments at public hospitals in Spain. Read More

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Formalin-fixed tissue Mohs surgery (slow Mohs) for trichoblastic carcinoma.

J Eur Acad Dermatol Venereol 2022 Jun 10. Epub 2022 Jun 10.

Department of Dermatology, Ambroise Paré Hospital, Boulogne-Billancourt, France.

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Keystone Flap Reconstruction After Large Mohs Micrographic Surgery Defect of Basal Cell Carcinoma on the Upper Arm: A Case Report.

Cureus 2022 Jun 7;14(6):e25709. Epub 2022 Jun 7.

Department of Dermatology, Case Western Reserve University, School of Medicine and MetroHealth System, Cleveland, USA.

Large defects after Mohs micrographic surgery present a reconstructive challenge. The keystone design perforator island flap has proven to be simple and effective in the repair of large skin defects after cancer removal. We present a case of such a defect on the upper arm that was successfully reconstructed with the keystone flap. Read More

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Upper eyelid reconstruction using an advancement tarso-conjunctival flap.

Eur J Ophthalmol 2022 Jun 7:11206721221107302. Epub 2022 Jun 7.

Department of Ophthalmology, Queen's Medical Centre, 105590Nottingham University Hospital, Nottingham, UK.

Purpose And Context: Upper eyelid reconstruction is particularly complex due to its functional and aesthetic importance. We aim to assess the outcomes/ complications of patients who undergo upper eyelid reconstruction of the posterior lamellae with an advancing tarsonconjunctival flap from the same affected eyelid, following excision of a periocular malignancy by Mohs Micrographic Surgery.

Method: A retrospective consecutive case note review of all eight patients who underwent the procedure between May 2016 and Jan 2021 were included. Read More

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Response to "Comment on 'Disparities in nonmelanoma skin cancer in Hispanic/Latino patients based on Mohs micrographic surgery defect size: A multicenter retrospective study'".

J Am Acad Dermatol 2022 Jun 3. Epub 2022 Jun 3.

Department of Dermatology, Keck School of Medicine of University of Southern California, Los Angeles, California.

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Necrosis of the Ear Following Skin Cancer Resection.

Cutis 2022 Apr;109(4):E2-E5

The Ohio State University Wexner Medical Center, Columbus.

We report 2 patients who underwent Mohs micrographic surgery (MMS) and operative closure on the ear. Both cases were complicated by necrosis resulting in the formation of auricular defects. These cases highlight the importance of the auricular vasculature and the associated watershed regions during operative planning for MMS as well as the complications that can arise with vascular compromise. Read More

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Autologous Fat Grafting for Plantar Fasciitis.

J Cutan Aesthet Surg 2022 Jan-Mar;15(1):97-98

Division of Dermatologic and Mohs Surgery, Mount Sinai Hospital, New York, NY, USA.

Plantar fasciitis is the most common cause of heel pain, accounting for up to 15% of medical foot inquiries. Autologous fat grafting (AFG) is a promising new treatment for plantar fasciitis, whereby the injection of fat may promote a cushioning effect on the heel and reduce plantar pressure, thereby reducing heel pain. We present the case of a patient with chronic plantar fasciitis treated with AFG with significant improvement in foot pain and functional scores. Read More

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Association of Tumor Characteristics With Insurance Type Among Patients Undergoing Mohs Micrographic Surgery for Nonmelanoma Skin Cancer.

JAMA Dermatol 2022 Jun 1. Epub 2022 Jun 1.

Division of Dermatology, Department of Internal Medicine, Dell Medical School at The University of Texas at Austin.

Importance: Little is known about the association between insurance type and tumor or treatment characteristics among patients undergoing Mohs micrographic surgery (MMS) for nonmelanoma skin cancer (NMSC).

Objective: To investigate whether there are differences in tumor and treatment characteristics among patients undergoing MMS for NMSC by insurance type.

Design, Setting, And Participants: This retrospective cohort study included patients with NMSC who presented for surgery at an academic MMS practice between May 2017 and May 2019. Read More

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Multilobed flaps for intermediate and large nasal defects: Flap characteristics, patient outcomes, and provider experience at two institutions.

J Plast Reconstr Aesthet Surg 2022 Apr 25. Epub 2022 Apr 25.

Department of Dermatology, MetroHealth System, Cleveland, OH, United States; Case Western Reserve University, School of Medicine, Cleveland, OH, United States. Electronic address:

Background: While bilobed and trilobed transposition flaps are established workhorses for nasal reconstruction, their utility is often limited to defects less than 1.5 cm, subjecting patients to more involved multistage or cosmetically less favorable repairs. We highlight the use of bilobed and trilobed transposition flaps for intermediate (≥ 1. Read More

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Mohs micrographic surgery revisited: A multidisciplinary, collaborative approach for the treatment of aggressive and recurrent basal cell carcinoma on the head and neck.

J Plast Reconstr Aesthet Surg 2022 Apr 25. Epub 2022 Apr 25.

Dermatology and Venereology Division, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.

Mohs micrographic surgery is the preferred surgical option for high-risk basal cell carcinomas. In our institution, the method is exclusively used for the treatment of aggressive and recurrent facial tumours selected via multidisciplinary team meetings and consistently managed using a multidisciplinary approach. The aim of this retrospective patient-record study was to examine the outcomes for basal cell carcinomas managed with Mohs micrographic surgery and to present our experience from multidisciplinary team meetings and interdisciplinary collaborations. Read More

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Microscope Use in Mohs Micrographic Surgery: A Survey of Current and Former Mohs Surgery Fellowship Directors.

Dermatol Surg 2022 May 27. Epub 2022 May 27.

Dermatologic Surgery, Ascension St. Vincent Medical Center, Indianapolis, Indiana.

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From the Cochrane library: Interventions for melanoma in situ, including lentigo maligna.

J Am Acad Dermatol 2022 May 28. Epub 2022 May 28.

Department of Dermatology, University of Colorado Anschutz Medical Campus, Aurora, Colorado. Electronic address:

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Two methods using topographic landmarks to identify and preserve the spinal accessory nerve during dermatologic surgery.

J Am Acad Dermatol 2022 May 28. Epub 2022 May 28.

Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address:

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Preclinical Evaluation of a Humanized, Near-Infrared Fluorescent Antibody for Fluorescence-Guided Surgery of MUC16-Expressing Pancreatic Cancer.

Mol Pharm 2022 May 31. Epub 2022 May 31.

Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska 68198, United States.

Surgery remains the only potentially curative treatment option for pancreatic cancer, but resections are made more difficult by infiltrative disease, proximity of critical vasculature, peritumoral inflammation, and dense stroma. Surgeons are limited to tactile and visual cues to differentiate cancerous tissue from normal tissue. Furthermore, translating preoperative images to the intraoperative setting poses additional challenges for tumor detection, and can result in undetected and unresected lesions. Read More

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Dermatofibrosarcoma protuberans with unusual presentation in vulva.

Medicina (B Aires) 2022 ;82(3):441-444

División Ciencias de la Salud, Universidad del Norte, Barranquilla, Colombia.

Gynecological sarcomas are rare and their location in the vulva and vagina has an incidence of 5% of all malignant neoplasms in the female genital tract. We present the case of a 54-year-old patient with a diagnosis of dermatofibrosarcoma protuberans in the vulva, an infrequent pathology with less than 60 cases reported worldwide in this anatomical location. Clinically, it is locally aggressive, due to the proliferation of spindle cells with pleomorphism and frequent mitotic figures infiltrating the reticular dermis and subcutaneous cellular tissue, giving rise to variable size tumors with high local recurrence rates. Read More

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