4,610 results match your criteria Mohs Micrographic Surgery


Mohs micrographic surgery: a treatment method for many non-melanocytic skin cancers.

Dermatol Online J 2020 Apr 15;26(4). Epub 2020 Apr 15.

Department of Dermatology, Baylor College of Medicine, Houston, TX.

Mohs micrographic surgery (MMS) is a breakthrough surgical technique that has changed the management of neoplasms in dermatology. Through continued practice and evolution, MMS now can successfully treat a variety of rare non-melanocytic cutaneous malignancies for which achieving remission and the optimal aesthetic result after surgery was previously challenging. Mohs micrographic surgery has utility for conditions besides melanoma. Read More

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Standards, Equality and Safety in Mohs Micrographic Surgery for patients living with HIV.

Clin Exp Dermatol 2020 Jul 3. Epub 2020 Jul 3.

Dermatology Unit, Ninewells Hospital, James Arrott Drive, Dundee, DD2 9SY, Scotland.

Dear Editor, the number of people living with diagnosed HIV (PLWHIV) is growing older and diversifying. In 2017, 98% of people receiving HIV care in the UK were on antiretroviral treatment and of those, 97% had an undetectable viral load (uVL). There is consensus that HIV with an uVL is not infectious. Read More

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http://dx.doi.org/10.1111/ced.14367DOI Listing

Re: "Development of a Patient-Reported Outcome Measure for Mohs Reconstruction" by Kavanagh and Christophel.

Facial Plast Surg Aesthet Med 2020 Jul 2. Epub 2020 Jul 2.

Division of Plastic and Reconstructive Surgery, Brigham and Women's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1089/fpsam.2020.0264DOI Listing

Correlation Between Demographic and Tumor Characteristics in Non-melanoma Skin Cancers Submitted to Mohs Micrographic Surgery.

In Vivo 2020 Jul-Aug;34(4):2107-2111

Department of Postgraduate Studies, University Center Health ABC (FMABC), Santo André, Brazil.

Background/aim: Non-melanoma skin cancer (NMSC) is the most prevalent type of cancer in adults. Surgery remains the golden-standard treatment for this disease. Mohs micrographic surgery (MMS), a surgical technique, is based on the three-dimensional histopathological examination of the margin and surgical bed, layer by layer, in the excised tissue allowing for the determination of the location of the residual tumor, for its complete excision, with high cure rates and preservation of the unaffected tissue. Read More

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http://dx.doi.org/10.21873/invivo.12015DOI Listing

Expert Opinion Regarding Appropriately Timing Dermatological Surgeries in Patients With Recent Myocardial Infarctions.

Dermatol Surg 2020 Jun 25. Epub 2020 Jun 25.

Department of Dermatology, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.

Background: There is limited data on the risk of perioperative myocardial infarctions (MIs) in patients with a recent MI who undergo dermatologic surgeries.

Objective: Present the recommendations of dermatologic surgeons and cardiologists to determine the safety of dermatologic surgeries after a recent MI.

Methods: An electronic survey was distributed to Mohs surgeons and cardiologists to infer the risk of major adverse cardiac events (MACE) inherent to dermatologic surgery and determine timing of dermatologic surgery in patients with a recent MI. Read More

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http://dx.doi.org/10.1097/DSS.0000000000002462DOI Listing

Foreign Body Reaction to Hydrophilic Polymer Following Mohs Micrographic Surgery.

Dermatol Surg 2020 Jun 25. Epub 2020 Jun 25.

Department of Dermatology, University of Texas Medical Branch, Galveston, Texas.

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http://dx.doi.org/10.1097/DSS.0000000000002510DOI Listing

Facial malignancies in patients referred for mohs micrographic surgery: a retrospective review of the impact of hair growth on tumor and defect size.

Cutis 2020 May;105(5):265-268

Department of Dermatology, The University of North Carolina at Chapel Hill, USA.

There is a lack of data characterizing tumors located within male facial hair subunits and determining if terminal hair growth obscures tumor detection, thus leading to a delay in diagnosis. Our objective was to evaluate the difference in cutaneous tumor size in men who had facial hair compared to men without facial hair. This retrospective chart review analyzed Mohs micrographic surgery cases of tumors located within facial hair subunits from January 2015 to December 2018 at The University of North Carolina at Chapel Hill. Read More

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The impact of COVID-19 pandemics on dermatologic surgery: real-life data from the Italian Red-Zone.

J Dermatolog Treat 2020 Jun 30:1-20. Epub 2020 Jun 30.

Department of Health Sciences, University of Eastern Piedmont, Novara, Italy.

: The COVID-19 pandemic is challenging healthcare systems worldwide. Dermatology had to re-prioritize visits, guarantee urgent care, and ensure continuity for chronic patients.: To evaluate the COVID-19 impact on dermatologic surgery outpatient management. Read More

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http://dx.doi.org/10.1080/09546634.2020.1789044DOI Listing

A 10-year Review of Surgical Management of Dermatofibrosarcoma Protuberans.

Br J Dermatol 2020 Jun 29. Epub 2020 Jun 29.

Department of Dermatology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

Background: Dermatofibrosarcoma protuberans (DFSP) is a rare skin cancer. Standard treatment in the United Kingdom (UK) is either surgical wide local excision (WLE) or Mohs micrographic surgery (MMS). It is unclear which approach has the lower recurrence rate. Read More

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http://dx.doi.org/10.1111/bjd.19346DOI Listing

Postoperative complications in dermatological patients undergoing microscopically controlled surgery in inpatient setting (next-day surgery): A single-center epidemiological study.

J Dtsch Dermatol Ges 2020 Jun 28. Epub 2020 Jun 28.

Department of Dermatology and Allergology, University Hospital of RWTH Aachen, Aachen, Germany.

Background: Surgical site infections (SSI), bleeding, and necrosis are possible complications of dermatological surgery, and their rates are well described for Mohs surgery (same-day surgery). However, there are only limited data on their occurrence in microscopically controlled surgery of the form in which it is practiced in German hospitals (next-day surgery).

Materials And Methods: We performed a retrospective analysis of patient records of patients hospitalized for microscopically controlled surgery during the year 2017 (12 months) in the Department of Dermatology and Allergology at the University Hospital of the RWTH Aachen (Aachen, Germany). Read More

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http://dx.doi.org/10.1111/ddg.14148DOI Listing

Impact of COVID-19 on Mohs micrographic surgery: UK-wide survey and recommendations for practice.

Clin Exp Dermatol 2020 Jun 27. Epub 2020 Jun 27.

Dermatological Surgery & Laser Unit, St John's Institute of Dermatology, Guy's & St Thomas' NHS Foundation Trust, London, UK.

Coronavirus Disease 2019 (COVID-19) pandemic has overwhelmed and disrupted healthcare systems including dermatology services. National directives were issued to reduce patient footfall within hospitals in anticipation of a deluge of COVID-19 admissions. We conducted a survey focusing on the impact of the pandemic upon Mohs micrographic surgery (MMS) practices and invited all British Society for Dermatological Surgery (BSDS) members undertaking MMS to complete over three weeks commencing 27 April 2020. Read More

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http://dx.doi.org/10.1111/ced.14356DOI Listing

A Deep Learning Algorithm to Detect the Presence of Basal Cell Carcinoma on Mohs Micrographic Surgery Frozen Sections.

J Am Acad Dermatol 2020 Jun 23. Epub 2020 Jun 23.

University of California San Diego, Department of Dermatology.

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http://dx.doi.org/10.1016/j.jaad.2020.06.080DOI Listing

Safety margins for dermatofibrosarcoma protuberans: a comparison between wide local excision and Mohs Tubingen technique.

Eur J Dermatol 2020 Jun 23. Epub 2020 Jun 23.

Department of Health Science, University of Eastern Piedmont, Novara.

Background: Dermatofibrosarcoma protuberans (DFSP) is a rare, locally infiltrating, rarely metastasizing, soft tissue tumour. Due to its indistinct margins, local aggressive behaviour and high recurrence rate, the surgical approach is complex. Micrographic surgery and variants of this technique, e. Read More

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http://dx.doi.org/10.1684/ejd.2020.3771DOI Listing

Improving the Appearance of Surgical Facial Scars With IncobotulinumtoxinA and Microneedling.

J Drugs Dermatol 2020 Jun;19(6):611-615

Background: The appearance of post-surgical scars on the face is a major concern for surgeons and a source of anxiety for patients after Mohs surgery due to nonmelanoma skin cancer (NMSC). The objective of this retrospective study was to assess the effectiveness of combining incobotulinumtoxinA and microneedling to improve the appearance of post-operative facial scars. Enrolled subjects underwent surgical removal of facial NMSCs followed by flap reconstruction by the same surgeon during 2014 (n=35) and 2015 (n=35). Read More

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http://dx.doi.org/10.36849/JDD.2020.10.36849/JDD.2020.4772DOI Listing

Skin Biopsy and Skin Cancer Treatment Utilization in the Medicare Population, 1993-2016.

J Am Acad Dermatol 2020 Jun 15. Epub 2020 Jun 15.

The Skin Cancer Center, Clinical Associate Professor- University of Cincinnati, 3024 Burnet Ave, Cincinnati, OH 45219; TriHealth-Good Samaritan Hospital: Micrographic Surgery and Dermatologic Oncology.

Background: Skin biopsies are increasing at a rapid rate and some may be unnecessary. Although skin cancer incidence is rising, there is varied biopsy accuracy between dermatologists and Advanced Practice Professionals (APPs). A comparison of CPT code utilization for skin biopsy and skin cancer treatment over 18 years-time and comparison of provider types is needed. Read More

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http://dx.doi.org/10.1016/j.jaad.2020.06.030DOI Listing

The Effects of Primary Defect Characteristics on Reconstruction Type and Adjunctive Intervention in Mohs Micrographic Surgery: A Retrospective Review.

J Drugs Dermatol 2020 Mar;19(3):264-270

Background: Cosmetic concerns following Mohs Micrographic surgery (MMS) are significant and may require adjunctive treatments for unsatisfactory appearance.

Objective: To determine factors associated with adjunctive cosmetic intervention for facial defects following MMS.

Methods And Materials: A retrospective review of 699 patients undergoing repair of facial defects after MMS from 2008-2018 was performed. Read More

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Commentary on Indications and Outcomes of Mohs Micrographic Surgery Using a Multidisciplinary Approach.

Dermatol Surg 2020 Jun 9. Epub 2020 Jun 9.

Department of Dermatology, MetroHealth Hospital, Cleveland, Ohio.

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http://dx.doi.org/10.1097/DSS.0000000000002413DOI Listing

Indications and Outcomes of Mohs Micrographic Surgery Using a Multidisciplinary Approach: A Decade of Experience.

Dermatol Surg 2020 Jun 9. Epub 2020 Jun 9.

Department of Otolaryngology, Division of Facial Plastic and Reconstructive Surgery, University of Rochester Medical Center Rochester, New York, New York.

Background: Traditional approaches of staged outpatient Mohs Micrographic Surgery (MMS) in nonmelanoma skin cancer (NMSC) followed by reconstruction is not possible in a subset of patients.

Objective: Assess the indications and outcomes of a multidisciplinary approach MMS.

Methods And Materials: Retrospective, single-surgeon, single Mohs specialist, university-based tertiary care referral practice, including all MMS performed in the operating room setting with concurrent reconstruction in patients from 2008 to 2018 with minimum follow-up of 6 months. Read More

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http://dx.doi.org/10.1097/DSS.0000000000002467DOI Listing

Photographic assessment of post-surgical facial scars epidermally sutured with rapidly-absorbable polyglactin 910 or nylon: A randomized clinical trial.

J Am Acad Dermatol 2020 Jun 10. Epub 2020 Jun 10.

Department of Dermatology and Skin Science, University of British Columbia, Vancouver, Canada.

Background: Surgeons use absorbable and non-absorbable sutures for epidermal wound closure. No large, randomized studies have compared the effect of these suture types on facial scar appearance.

Objective: To assess post-surgical facial scar appearance using either rapidly-absorbable polyglactin 910 or nylon for epidermal closure. Read More

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http://dx.doi.org/10.1016/j.jaad.2020.06.016DOI Listing

Assessment of the accessibility and content of dermatology fellowship websites.

J Am Acad Dermatol 2020 Jun 9. Epub 2020 Jun 9.

Department of Dermatology, The George Washington School of Medicine and Health Sciences, Washington, DC. Electronic address:

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http://dx.doi.org/10.1016/j.jaad.2020.06.017DOI Listing

Postoperative Bleeding Complications Associated with Blood Thinning Agents during Mohs Micrographic Surgery: A Retrospective Cohort Study.

J Am Acad Dermatol 2020 Jun 8. Epub 2020 Jun 8.

Department of Dermatology, University of Texas Southwestern Medical School. Electronic address:

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http://dx.doi.org/10.1016/j.jaad.2020.06.011DOI Listing
June 2020
4.449 Impact Factor

Dermatofibrosarcoma Protuberans: Update on the Diagnosis and Treatment.

J Clin Med 2020 Jun 5;9(6). Epub 2020 Jun 5.

Department of Dermatology, Cleveland Clinic, Cleveland, OH 44195, USA.

Dermatofibrosarcoma protuberans (DFSP) is a slow growing, low- to intermediate-grade dermal soft-tissue tumor. It has a high local recurrence rate but low metastatic potential. It is characterized by a uniform spindle cell arrangement, classically with a storiform pattern and CD34 immunoreactivity. Read More

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http://dx.doi.org/10.3390/jcm9061752DOI Listing

Facial trichoblastic carcinoma treated with Mohs micrographic surgery: A new indication for Mohs?

JAAD Case Rep 2020 Jun 1;6(6):561-562. Epub 2020 Jun 1.

Texas Tech University Health Sciences Center Department of Dermatology, Lubbock, Texas.

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http://dx.doi.org/10.1016/j.jdcr.2020.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265050PMC

Myxoid dermatofibrosarcoma protuberans treated with Mohs micrographic surgery.

JAAD Case Rep 2020 Jun 1;6(6):558-560. Epub 2020 May 1.

The Facial Plastics and Dermatology Department, The Toledo Clinic, Toledo, Ohio.

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http://dx.doi.org/10.1016/j.jdcr.2020.03.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265059PMC

A retrospective case series evaluating the efficacy of pre-operative, intra-incisional antibiotic prophylaxis in Mohs micrographic surgery: an effective method to reduce surgical site infections and minimize systemic antibiotic use.

J Am Acad Dermatol 2020 Jun 2. Epub 2020 Jun 2.

Zitelli and Brodland Skin Cancer Center, Pittsburgh, PA 15232; University of Pittsburgh Medical Center, Pittsburgh, PA 15232.

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http://dx.doi.org/10.1016/j.jaad.2020.05.146DOI Listing

A Retrospective Analysis of Atypical Fibroxanthoma Treated with Mohs Surgery at a Single Academic Institution.

J Am Acad Dermatol 2020 Jun 1. Epub 2020 Jun 1.

Department of Dermatology, University of Texas Southwestern Medical Center. Electronic address:

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http://dx.doi.org/10.1016/j.jaad.2020.05.123DOI Listing
June 2020
4.449 Impact Factor

Treatment of periocular basal cell carcinoma with neoadjuvant vismodegib.

Am J Ophthalmol Case Rep 2020 Sep 23;19:100755. Epub 2020 May 23.

Baylor Scott and White Department of Ophthalmology - Texas A&M University, 1815 S 31st Street, Temple, TX, 76508, USA.

Purpose: To report a case of a locally advanced periocular basal cell carcinoma treated with neoadjuvant Vismodegib therapy prior to surgery.

Observations: A 63-year-old female presented to the oculoplastics clinic with biopsy-proven basal cell carcinoma of the right periorbital region causing significant cicatricial ectropion of the right lower eyelid. The medial canthal lesion involved nearly the entire right lower eyelid with extension onto the cheek, the medial half of the right upper eyelid, the palpebral and bulbar conjunctiva, as well as the right lacrimal system. Read More

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http://dx.doi.org/10.1016/j.ajoc.2020.100755DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262551PMC
September 2020

Collision tumor of microcystic adnexal carcinoma and squamous cell carcinoma discovered on Mohs sections.

JAAD Case Rep 2020 Jun 18;6(6):479-481. Epub 2020 Apr 18.

Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas.

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http://dx.doi.org/10.1016/j.jdcr.2020.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256221PMC

Antibiotic Practices in Mohs Micrographic Surgery.

J Drugs Dermatol 2020 May;19(5):493-497

Background: Mohs micrographic surgery is a safe procedure with low rates of infection.

Objective: To establish current antibiotic prescribing practices amongst Mohs surgeons.

Methods And Materials: 16-question survey sent to American College of Mohs Surgery members. Read More

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May 2020
1.320 Impact Factor

Topical Fluorouracil Therapy for Residual Superficial Basal Cell Carcinoma Following Mohs Micrographic Surgery.

J Drugs Dermatol 2020 May;19(5):485-486

When treating invasive basal cell carcinoma (BCC) with Mohs micrographic surgery (MMS), including infiltrative and nodular subtypes, the goal is complete surgical removal of the tumor. In some cases, after several stages of MMS, residual foci of superficial BCC are noted with no dermal invasive components apparent. Some patients and surgeons have opted for halting surgery and treating residual superficial BCC with adjuvant topical fluorouracil. Read More

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Pull Through Marking Technique for Precise Contouring Sutures.

Dermatol Surg 2020 May 29. Epub 2020 May 29.

Dayton Skin Surgery Center, Dayton Skin Care Specialists, Dayton, Ohio.

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http://dx.doi.org/10.1097/DSS.0000000000002416DOI Listing

Melanoma Treated With Mohs Micrographic Surgery Using a Novel-Modified 15-Minute MART-1 Immunostain: Discussion of Technique and Experience.

Dermatol Surg 2020 May 29. Epub 2020 May 29.

Department of Dermatology, University of Minnesota, Minneapolis, Minnesota.

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http://dx.doi.org/10.1097/DSS.0000000000002435DOI Listing

Unusual Calcification Mimicking Periosteal Tumor Invasion in a Squamous Cell Carcinoma Treated With Mohs Micrographic Surgery.

Dermatol Surg 2020 May 29. Epub 2020 May 29.

Division of Dermatologic Surgery and Cutaneous Oncology, Department of Dermatology, Indiana University School of Medicine, Indianapolis, Indiana.

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http://dx.doi.org/10.1097/DSS.0000000000002410DOI Listing

Incidence of Surgical Site Infections in Second Intention Healing After Dermatologic Surgery.

Dermatol Surg 2020 May 29. Epub 2020 May 29.

Department of Dermatology, Cooper Center for Dermatologic Surgery, Evesham, New Jersey.

Background: There are few studies analyzing the surgical site infection (SSI) rate of second intention wounds after dermatologic surgery, and the results are inconclusive. Yet, the current dogma in dermatologic surgery is that wounds healed by second intention have lower infection rates.

Objective: To determine the rate of SSI and associated pathogenic organisms of second intention wounds compared with sutured wounds after skin cancer extirpation. Read More

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http://dx.doi.org/10.1097/DSS.0000000000002409DOI Listing

Margins of Melanoma Excision and Modifications to Standards.

Surg Oncol Clin N Am 2020 Jul;29(3):339-347

Cancer Institute of New Jersey, 195 Little Albany Street, Room 3005, New Brunswick, NJ 08903, USA. Electronic address:

Surgery with wide local excision is the mainstay of treatment for primary melanoma. Surgical margins differ depending on the depth of the primary lesion, subtype, and anatomic, cosmetic, or functional considerations. Adjuncts or alternative treatments to wide local excision are limited to specific patient populations and mainly experimental in nature. Read More

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http://dx.doi.org/10.1016/j.soc.2020.02.002DOI Listing

Management of primary skin cancer during a pandemic: Multidisciplinary recommendations.

Cancer 2020 Jun 1. Epub 2020 Jun 1.

Division of Dermatologic Surgery, Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

During the coronavirus disease 2019 (COVID-19) pandemic, providers and patients must engage in shared decision making regarding the pros and cons of early versus delayed interventions for localized skin cancer. Patients at highest risk of COVID-19 complications are older; are immunosuppressed; and have diabetes, cancer, or cardiopulmonary disease, with multiple comorbidities associated with worse outcomes. Physicians must weigh the patient's risk of COVID-19 complications in the event of exposure against the risk of worse oncologic outcomes from delaying cancer therapy. Read More

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http://dx.doi.org/10.1002/cncr.32969DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301000PMC
June 2020
4.889 Impact Factor

Basal cell carcinoma stroma as a mimicker of lymphatic invasion: A case report.

SAGE Open Med Case Rep 2020 29;8:2050313X20919602. Epub 2020 Apr 29.

Department of Dermatology, Centre Hospitalier de l'Université de Montréal (CHUM), Montreal, QC, Canada.

Basal cell carcinoma metastases are rare. We report a case of an 83 year-old male with recurrent cutaneous infiltrative basal cell carcinoma on the right vertex with tumor aggregates of infiltrative basal cell carcinoma in the lymphatic vessels of the superficial dermis strongly suspected on pathology slide evaluation during Mohs micrographic surgery. D2-40 immunohistochemical stain allows the detection of lymphatic invasion by highlighting endothelial cells. Read More

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http://dx.doi.org/10.1177/2050313X20919602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7234329PMC

Comparing clinical acne vulgaris severity to adolescent and parent perceptions of acne severity and impact on quality of life.

Pediatr Dermatol 2020 May 27. Epub 2020 May 27.

Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

Background/objectives: Little research has compared clinician acne severity assessment with either adolescent- or parent-rated scales of acne severity or impact on quality of life (QOL). We sought to assess how adolescents and their parents perceive the severity and impact of acne on the adolescent's QOL and correlate this with clinical severity.

Methods: Each adolescent and a parent completed a validated QOL survey regarding the adolescent's acne and rated the adolescent's acne severity and QOL impact using a Likert scale. Read More

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http://dx.doi.org/10.1111/pde.14034DOI Listing

Commentary on Treatment of Hypertrophic Burn and Traumatic Scars With 2940 mm Fractional Ablative Er: YAG.

Authors:
David M Ozog

Dermatol Surg 2020 Jun;46(6):794-795

Division of Mohs and Dermatological Surgery, Henry Ford Hospital, Detroit, Michigan.

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http://dx.doi.org/10.1097/DSS.0000000000002194DOI Listing

Factors Impacting Patient Ratings of Mohs Surgeons: Lessons Gleaned from Analysis of 17,527 Online Reviews.

J Am Acad Dermatol 2020 May 22. Epub 2020 May 22.

Columbia University Irving Medical Center, Department of Dermatology.

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http://dx.doi.org/10.1016/j.jaad.2020.05.082DOI Listing

Complete visualization of epidermal margin during ex vivo confocal microscopy of excised tissue with 3D-mosaicking and intensity projection.

J Am Acad Dermatol 2020 May 16. Epub 2020 May 16.

Memorial Sloan Kettering Cancer Center, Dermatology Service, Department of Medicine, New York (USA). Electronic address:

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http://dx.doi.org/10.1016/j.jaad.2020.05.044DOI Listing

Eyelid Complications Associated with Surgery for Periocular Cutaneous Malignancies.

Facial Plast Surg 2020 Apr 15;36(2):166-175. Epub 2020 May 15.

Department of Ophthalmology, Kellogg Eye Center, University of Michigan, Ann Arbor, Michigan.

Periocular skin is highly prone to malignancies, especially basal cell and squamous cell carcinomas. Because of the complex anatomy and eye-protecting functions of the periocular tissues, treatment of these cancers requires special considerations. Mohs micrographic surgery is usually the treatment of choice, whenever possible, in order to enhance margin control while limiting collateral damage to nearby normal structures. Read More

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http://dx.doi.org/10.1055/s-0040-1709515DOI Listing
April 2020
0.992 Impact Factor

High-Risk Nonmelanoma Skin Cancers: Identification, Management, and Reconstruction.

Facial Plast Surg 2020 Apr 15;36(2):141-147. Epub 2020 May 15.

Department of Otolaryngology-Head and Neck Surgery, University of Colorado, Aurora, Colorado.

High-risk nonmelanoma skin cancers of the head and neck may be identified through a variety of tumor risk factors, including location on the lips or ears, size > 2 cm, recurrence, patient immunocompromised status, poor tumor differentiation, > 6 mm thickness, Clark level V depth of invasion, and presence of perineural spread. Surgical excision is the mainstay of treatment, with Mohs' micrographic surgery typically preferred to standard surgical excision. When reconstructing these defects, ensuring negative margins is of utmost importance and delaying reconstruction until confirmation of margins is recommended. Read More

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http://dx.doi.org/10.1055/s-0040-1709132DOI Listing

Mohs Surgery versus Standard Local Excision for Basal Cell Carcinoma, Squamous Cell Carcinoma, and Melanoma Skin Cancer.

Facial Plast Surg 2020 Apr 15;36(2):133-140. Epub 2020 May 15.

Department of Dermatology, University of Michigan, Ann Arbor, Michigan.

Basal cell carcinoma, squamous cell carcinoma, and melanoma represent the three most common skin cancers that occur on the face. The most common surgical treatments for facial skin cancers are Mohs' surgery and standard local excision. The effective utilization of either of these techniques is based on tumor and patient risk stratification incorporating known risk factors for occult invasion and local recurrence, combined with patient comorbidities, expectations, and desires. Read More

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http://dx.doi.org/10.1055/s-0040-1709142DOI Listing

Development of a MUC16-Targeted Near-Infrared Fluorescent Antibody Conjugate for Intraoperative Imaging of Pancreatic Cancer.

Mol Cancer Ther 2020 May 13. Epub 2020 May 13.

Department of Pharmaceutical Sciences, University of Nebraska Medical Center

Surgical resection is currently the only potentially curative option for patients with pancreatic cancer. However, the five-year survival rate after resection is only 25%, due in part to high rates of R1 resections, in which cells are left behind at the surgical margin, resulting in disease recurrence. Fluorescence-guided surgery (FGS) has emerged as a method to reduce incomplete resections and improve intraoperative assessment of cancer. Read More

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http://dx.doi.org/10.1158/1535-7163.MCT-20-0033DOI Listing

Do Postoperative Antibiotics Affect Outcomes in Mohs Reconstructive Surgery?

Laryngoscope 2020 May 13. Epub 2020 May 13.

Department of Otolaryngology-Head and Neck Surgery,, University of Virginia, Charlottesville, Virginia, U.S.A.

Objectives/hypothesis: The prescribing of postoperative antibiotics for patients undergoing Mohs reconstructive surgery has increased in the last decade, while antibiotic resistance has been increasing. We hypothesized that routine prescribing of postoperative antibiotics after Mohs reconstruction does not decrease the risk of surgical site infection.

Study Design: Retrospective, single-institution cohort study. Read More

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http://dx.doi.org/10.1002/lary.28700DOI Listing

Why it's hard to see a dermatologist for a skin exam: the patient perspective.

Arch Dermatol Res 2020 May 12. Epub 2020 May 12.

University Hospitals Cleveland Medical Center, 11100 Euclid Ave., Cleveland, OH, 44106, USA.

Background: In-office skin exams are recommended at least annually for patients who are diagnosed with a basal cell carcinoma or squamous cell carcinoma, but it is unknown what proportion of these patients are receiving skin exams. There are a multitude of reasons why patients have difficulty getting skin exams.

Aim: To assess the proportion of patients at our institution who received a skin exam in the 12 months following removal of a basal cell carcinoma or squamous cell carcinoma by Mohs micrographic surgery and to assess the barriers to care that patients faced in receiving a skin exam. Read More

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http://dx.doi.org/10.1007/s00403-020-02080-3DOI Listing