6,905 results match your criteria Mitral Valve Prolapse


Killing two birds with one stone-MitraClip for flail P2 and systolic anterior motion of mitral valve: a case report.

Eur Heart J Case Rep 2018 Dec 11;2(4):yty146. Epub 2018 Dec 11.

National Heart Centre Singapore, 5 Hospital Drive, Singapore, Singapore.

Background: The MitraClip system has been used extensively in high-risk patients with severe degenerative mitral regurgitation (MR). Recent reports have demonstrated the feasibility of using the MitraClip device to treat systolic anterior motion (SAM) of the mitral valve in obstructive hypertrophic cardiomyopathy (HOCM).

Case Summary: We report the case of a 76-year-old lady who had both symptomatic severe degenerative MR and HOCM that were refractory to medical therapy. Read More

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http://dx.doi.org/10.1093/ehjcr/yty146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426007PMC
December 2018

Chordal replacement versus quadrangular resection in degenerative posterior mitral leaflet repair.

J Thorac Dis 2019 Mar;11(3):827-838

Department of Cardiac Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

Background: As an alternative to quadrangular resection (QR), little is known of the potential of chordal replacement (CR) for treating posterior mitral leaflet (PML) prolapse when comparing these two techniques. This study aimed to assess mid- to long-term outcomes of CR versus QR for isolated degenerative PML (idPML) repair.

Methods: We reviewed 112 consecutive patients using CR or QR for idPML repair from 4/2010 to 12/2015. Read More

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http://dx.doi.org/10.21037/jtd.2019.02.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462675PMC

A Band That Causes Leaky Valves: Severe Mitral Regurgitation due to Left Atrial Fibrous Band-A Case Report and Literature Review.

Case Rep Cardiol 2019 19;2019:2458569. Epub 2019 Mar 19.

Newark Beth Israel Medical Center, Newark, NJ, USA.

Left atrial fibrous band is a rare clinical and echocardiographic finding characterized by the presence of a fibrous band attached to the mitral valve. Diagnosis is accomplished with transesophageal echocardiography (TEE), live 3D imaging, or cardiac MRI. Most patients are asymptomatic and incidental findings. Read More

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http://dx.doi.org/10.1155/2019/2458569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444234PMC

Effect of Progressive Left Ventricular Dilatation on Degree of Mitral Regurgitation Secondary to Mitral Valve Prolapse.

Am J Cardiol 2019 Mar 13. Epub 2019 Mar 13.

Internal Medicine (Division of Cardiology), Baylor University Medical Center, Baylor Scott & White Health, Dallas, Texas.

Described herein is a 71-year-old man who at age 61 was found by echocardiogram to have severe mitral regurgitation (MR) from mitral valve prolapse. During the subsequent 9 years the MR progressively lessened as his left ventricular cavity dilated and his ejection fraction progressively fell such that just before orthotopic heart transplantation the degree of MR was no longer severe, and the prolapse of the mitral leaflets had disappeared. This report describes this unique patient. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00029149193029
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http://dx.doi.org/10.1016/j.amjcard.2019.02.046DOI Listing
March 2019
1 Read

Mechanical dispersion and arrhythmic mitral valve prolapse: substrate and trigger in electrical instability.

Heart 2019 Apr 10. Epub 2019 Apr 10.

Cardiovascular Pathology Unit, Department of Cardiac-Thoracic-Vascular Sciences and Public Health, University of Padua Medical School, Padova, Italy.

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http://dx.doi.org/10.1136/heartjnl-2019-314788DOI Listing
April 2019
1 Read

Early Impairment Left Ventricular Mechanics in Children With Mitral Valve Prolapse.

Authors:
Serkan F Çelik

Am J Cardiol 2019 Mar 18. Epub 2019 Mar 18.

Department of Pediatrics, Division of Pediatric Cardiology, Adnan Menderes University Hospital, Aydın, Turkey. Electronic address:

Early impairment of left ventricular (LV) function has been reported in some inherited connective tissue diseases such as Marfan syndrome or rheumatic heart disease in pediatric patients. However, there is no study about cardiac strain in pediatric patients with primary mitral valve prolapse (MVP). The aim of this study was to evaluate the LV functions in pediatric patients with primary MVP, mild or moderate mitral regurgitation (MR), and normal LV ejection fraction. Read More

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http://dx.doi.org/10.1016/j.amjcard.2019.03.009DOI Listing
March 2019
2 Reads

[Mitral valve pathologies].

MMW Fortschr Med 2019 Apr;161(6):46-49

Medizinische Universität Wien, Universitätsklinik für Innere Medizin II/Abteilung Kardiologie, Währinger Gürtel 18-20, A-1090, Wien, Österreich.

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http://dx.doi.org/10.1007/s15006-019-0359-1DOI Listing
April 2019
3 Reads

A Novel Truncating Variant in FLNC-Encoded Filamin C May Serve as a Proarrhythmic Genetic Substrate for Arrhythmogenic Bileaflet Mitral Valve Prolapse Syndrome.

Mayo Clin Proc 2019 Mar 29. Epub 2019 Mar 29.

Clinician-Investigator Training Program, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN. Electronic address:

A 51-year-old man with a long-standing history of bileaflet mitral valve prolapse accompanied by mitral annular disjunction and mild mitral regurgitation presented for evaluation of increasingly frequent palpitations. Ambulatory Holter monitoring, cardiac magnetic resonance imaging, serial transthoracic echocardiography, and diagnostic electrophysiology studies were consistent with a diagnosis of arrhythmogenic bileaflet mitral valve prolapse syndrome. Because of the presence of a similar phenotype in the proband's mother, brother, and maternal aunt, research-based whole exome sequencing was pursued and a novel truncating variant (p. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00256196183098
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http://dx.doi.org/10.1016/j.mayocp.2018.11.028DOI Listing
March 2019
4 Reads

Severe mitral regurgitation due to atrial tachyarrhythmia: cure by DC cardioversion.

Echo Res Pract 2019 Mar 1. Epub 2019 Mar 1.

B Shah, Cardiology, University Hospital Southampton, Southampton, SO16 6YD, United Kingdom of Great Britain and Northern Ireland.

A 62-year-old man admitted with palpitations had a 12-lead ECG that revealed atrial flutter with 2:1 AV block (rate 150bpm). Transthoracic echocardiography (TTE) revealed normal left ventricular size with impaired systolic function and severe MR. No MV prolapse was seen. Read More

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http://dx.doi.org/10.1530/ERP-19-0007DOI Listing
March 2019
6 Reads

From mitral valve prolapse to catheter ablation.

Eur Heart J 2019 Apr;40(16):1306

Department of Cardiology, University Hospital of Angers, MitoVasc Institute, Mitolab Team, University of Angers, UMR CNRS 6015 - INSERM U1083, 4 rue Larrey, Angers Cedex 9, France.

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http://dx.doi.org/10.1093/eurheartj/ehz139DOI Listing
April 2019
2 Reads

Papillary muscle ventricular arrhythmias in patients with arrhythmic mitral valve prolapse: Electrophysiologic substrate and catheter ablation outcomes.

J Cardiovasc Electrophysiol 2019 Mar 6. Epub 2019 Mar 6.

Section of Cardiac Electrophysiology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.

Background: Mitral valve prolapse (MVP) is a common valve condition and has been associated with sudden cardiac death. Premature ventricular contractions (PVCs) from the papillary muscles (PMs) may play a role as triggers for ventricular fibrillation (VF) in these patients.

Objectives: To characterize the electrophysiological substrate and outcomes of catheter ablation in patients with MVP and PM PVCs. Read More

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http://dx.doi.org/10.1111/jce.13900DOI Listing
March 2019
3 Reads

The Potential Beneficial Effects of Resveratrol on Cardiovascular Complications in Marfan Syndrome Patients⁻Insights from Rodent-Based Animal Studies.

Int J Mol Sci 2019 Mar 5;20(5). Epub 2019 Mar 5.

Department of Medical Biochemistry, Amsterdam UMC, Academic Medical Center, Amsterdam Cardiovascular Sciences, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.

Marfan syndrome (MFS) patients are at risk for cardiovascular disease. In particular, for aortic aneurysm formation, which ultimately can result in a life-threatening aortic dissection or rupture. Over the years, research into a sufficient pharmacological treatment option against aortopathy has expanded, mostly due to the development of rodent disease models for aneurysm formation and dissections. Read More

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http://dx.doi.org/10.3390/ijms20051122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429290PMC
March 2019
2 Reads

Myxomatous mitral valve disease in the miniature poodle: A retrospective study.

Vet J 2019 Feb 19;244:94-97. Epub 2018 Dec 19.

Department of Veterinary Clinical Sciences, North Carolina State University, Raleigh, NC, 27607, USA.

Myxomatous mitral valve disease (MMVD) is the most common cardiovascular disease in the dog. The natural history of the disease is wide ranging and includes patients without clinical signs as well as those with significant clinical consequences from cardiac arrhythmias, pulmonary hypertension and/or congestive heart failure. The factors that determine which dogs remain asymptomatic and which develop clinical disease are not known. Read More

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http://dx.doi.org/10.1016/j.tvjl.2018.12.019DOI Listing
February 2019
1 Read

Utility of Cardiac CT for Preoperative Evaluation of Mitral Regurgitation: Morphological Evaluation of Mitral Valve and Prediction of Valve Replacement.

Korean J Radiol 2019 Mar;20(3):352-363

Department of Radiology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

Objective: We aimed to investigate the diagnostic accuracy of cardiac computed tomography (CT) for the detection of mitral valve (MV) prolapse in mitral regurgitation (MR) with surgical findings as the standard reference, and to assess the predictability of MV replacement based on morphologic CT findings.

Materials And Methods: A total of 156 patients who had undergone preoperative cardiac CT and subsequently received MV surgery due to severe MR were retrospectively enrolled. Non-repairable MV was defined when at least one of the following conditions was met: 1) anterior leaflet prolapse, 2) bi-leaflet prolapse, or 3) valve morphology (leaflet thickening, calcification, or mitral annular calcification [MAC]). Read More

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http://dx.doi.org/10.3348/kjr.2018.0350DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389816PMC

[Pathological changes in extra- and intracranial vessel in young adults in the aspect of sudden death].

Zh Nevrol Psikhiatr Im S S Korsakova 2019;119(1):64-68

Sechenov's First Moscow State Medical University, Moscow, Russia.

Aim: To determine the main causes and pathomorphological characteristic of extra- and intracranial vessel pathological changes in young adults in the aspect of sudden death (SD).

Material And Methods: The authors investigated 10485 SD cases in young adults in the period from 2012 to 2016 (5 years) according to Moscow coroner bureau autopsy data. Morphological, chemical, histological, histochemical methods (staining with hematoxylin and eosin, van Gieson's stain, Masson's trichrome stain) were used. Read More

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http://dx.doi.org/10.17116/jnevro201911901164DOI Listing
January 2019
2 Reads

Myxomatous degeneration of the mitral valve.

Autops Case Rep 2018 Oct-Dec;8(4):e2018058. Epub 2018 Nov 30.

Universidade de São Paulo (USP), School of Medicine, Heart Institute, Laboratory of Pathology. São Paulo, SP, Brazil.

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http://dx.doi.org/10.4322/acr.2018.058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360834PMC
November 2018
1 Read

Mechanoelectric abnormality of "myocardial-valvular syndrome": More than a leaflet prolapse.

Authors:
Ugur Canpolat

Pacing Clin Electrophysiol 2019 05 28;42(5):566. Epub 2019 Feb 28.

Department of Cardiology, Arrhythmia and Electrophysiology Unit, Hacettepe University, Ankara, Turkey.

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http://dx.doi.org/10.1111/pace.13631DOI Listing
May 2019
2 Reads

Reply: Mechanoelectric abnormality of "myocardial-valvular syndrome": More than a leaflet prolapse.

Pacing Clin Electrophysiol 2019 05 24;42(5):567. Epub 2019 Mar 24.

Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio.

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http://doi.wiley.com/10.1111/pace.13621
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http://dx.doi.org/10.1111/pace.13621DOI Listing
May 2019
11 Reads
1.250 Impact Factor

Left ventricular mechanical dispersion predicts arrhythmic risk in mitral valve prolapse.

Heart 2019 Feb 12. Epub 2019 Feb 12.

Division of Cardiovascular Medicine, University of California, San Francisco, San Francisco, California, USA.

Objective: Bileaflet mitral valve prolapse (MVP) with either focal or diffuse myocardial fibrosis has been linked to ventricular arrhythmia and/or sudden cardiac arrest. Left ventricular (LV) mechanical dispersion by speckle-tracking echocardiography (STE) is a measure of heterogeneity of ventricular contraction previously associated with myocardial fibrosis. The aim of this study is to determine whether mechanical dispersion can identify MVP at higher arrhythmic risk. Read More

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http://dx.doi.org/10.1136/heartjnl-2018-314269DOI Listing
February 2019
5 Reads

Mitral Prolapse: An Old Mysterious Entity - The Incremental Role of Multimodality Imaging in Sports Eligibility.

J Cardiovasc Echogr 2018 Oct-Dec;28(4):207-217

Luigi Vanvitelli University, Monaldi Hospital, AORN Ospedali Dei Colli, Naples, Italy.

Mitral valve prolapse is generally a benign condition characterized by fibromyxomatous changes of the mitral leaflet with displacement into the left atrium and late-systolic regurgitation. Although it is an old clinical entity, it still arouses perplexity in diagnosis and clinical management. Complications, such as mitral regurgitation (MR), atrial fibrillation, congestive heart failure, endocarditis, ventricular arrhythmias, and sudden cardiac death (SCD), have been reported. Read More

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http://dx.doi.org/10.4103/jcecho.jcecho_42_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341849PMC
February 2019
2 Reads

Characteristics of mitral valve leaflet length in patients with pectus excavatum: A single center cross-sectional study.

PLoS One 2019 11;14(2):e0212165. Epub 2019 Feb 11.

Department of Clinical Laboratory, National Hospital Organization Yokohama Medical Center, Yokohama, Kanagawa, Japan.

The mitral valve morphology in patients with pectus excavatum (PE) has not been fully investigated. Thirty-five patients with PE, 46 normal controls, and patients with hypertrophic cardiomyopathy (HCM) who underwent 2 leaflet length measurements of Carpentier classification P2 and A2 using a transthoracic echocardiography were retrospectively investigated. The coaptation lengths and depths, papillary muscle tethering length, and mitral annular diameters were also measured. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212165PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370242PMC
February 2019
11 Reads

Incidence and Risk Factors of Cardiac Abnormalities in Patients with Idiopathic Scoliosis.

World Neurosurg 2019 Feb 8. Epub 2019 Feb 8.

Department of Musculoskeletal Oncology, Sun Yat-sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, China. Electronic address:

Objective: We sought to investigate the incidence of cardiac abnormalities in patients with idiopathic scoliosis and identify risk factors related to cardiac abnormalities.

Methods: A cohort of 531 patients with idiopathic scoliosis requiring surgical treatment in our hospital from March 2009 to August 2017 were recorded. Clinical data including medical records, radiograph, and echocardiogram were collected. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.177DOI Listing
February 2019
11 Reads

Predictive Factors for Progression of Mitral Regurgitation in Asymptomatic Patients With Mitral Valve Prolapse.

Am J Cardiol 2019 Apr 24;123(8):1309-1313. Epub 2019 Jan 24.

The Division of Cardiology, Department of Medicine, University of California, Sulpizio Cardiovascular Center, San Diego, California. Electronic address:

Risk factors predicting progression from low grade to severe mitral regurgitation (MR), which is a guideline criterion for surgical intervention, remain unknown. We hypothesized that abnormalities of cardiac structure and function may predict progression in MR severity. We followed 82 asymptomatic mitral valve prolapse (MVP) patients (65 ± 12 years, 51% men) with mild or moderate MR (36 mild, 46 moderate, mean LVEF: 62%), without significant co-morbidities. Read More

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http://dx.doi.org/10.1016/j.amjcard.2019.01.026DOI Listing
April 2019
2 Reads

Two-year evolution of latent rheumatic heart disease in Malawi.

Congenit Heart Dis 2019 Jan 31. Epub 2019 Jan 31.

Department of Pediatrics, Baylor College of Medicine Clinical Center of Excellence, Lilongwe, Malawi.

Background: In asymptomatic children, screening echocardiography has been used to attempt to diagnose rheumatic heart disease (RHD) at an early stage (latent RHD). World Heart Federation guidelines have standardized categorization of "definite," "borderline," or no RHD by echo findings. The progression of RHD diagnosed through echo screening is not known. Read More

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http://dx.doi.org/10.1111/chd.12756DOI Listing
January 2019
2 Reads

Exploring immunomodulation by endocrine changes in Lady Windermere syndrome.

Clin Exp Immunol 2019 Apr 27;196(1):28-38. Epub 2019 Feb 27.

Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.

Lung disease due to nontuberculous mycobacteria (NTM) occurs with disproportionate frequency in postmenopausal women with a unique phenotype and without clinically apparent predisposing factors. Dubbed 'Lady Windermere syndrome', the phenotype includes low body mass index (BMI), tall stature and higher than normal prevalence of scoliosis, pectus excavatum and mitral valve prolapse. Although the pathomechanism for susceptibility to NTM lung disease in these patients remains uncertain, it is likely to be multi-factorial. Read More

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http://dx.doi.org/10.1111/cei.13265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422647PMC
April 2019
2 Reads

Management and outcomes in mitral valve prolapse with ventricular arrhythmias undergoing ablation and/or implantation of ICDs.

Pacing Clin Electrophysiol 2019 Apr 6;42(4):447-452. Epub 2019 Mar 6.

Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic Cleveland, Ohio.

Background: While there is an association between isolated mitral valve prolapse (MVP) and sudden cardiac arrest (SCA), the baseline characteristics and outcomes of patients with isolated MVP who experience ventricular arrhythmias (VAs) and then subsequently undergo catheter ablation and/or implantable cardioverter defibrillator (ICD) implantation are unknown.

Methods: We performed a retrospective review of all patients at the Cleveland Clinic with isolated MVP between 1997 and 2016 who underwent VA catheter ablation or secondary prevention ICD implantation.

Results: Of 617 screened patients, we identified 43 patients with isolated MVP and significant VA who underwent ICD placement (n = 13, 30%) or catheter ablation (n = 30, 70%). Read More

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http://dx.doi.org/10.1111/pace.13613DOI Listing
April 2019
7 Reads
1.250 Impact Factor

Atrial Fibrillation and Mitral Valve Prolapse: Time to Intervene?

J Am Coll Cardiol 2019 Jan;73(3):275-277

Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jacc.2018.11.018DOI Listing
January 2019
2 Reads

Trends in mitral valve prolapse: a tertiary care center experience in Jeddah, Saudi Arabia.

Int J Gen Med 2019 14;12:55-61. Epub 2019 Jan 14.

Department of Internal Medicine, College of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia,

Background: Mitral valve prolapse (MVP) is the most common cardiac valvular abnormality in developed countries and it is associated with considerable morbidity and mortality.

Aim Of Work: To study the clinical presentations, risk factors, and echocardiographic features of patients with MVP in Jeddah, Saudi Arabia.

Materials And Methods: A retrospective chart review study was conducted in King Abdulaziz teaching hospital in Jeddah, Saudi Arabia, from 2007 to 2017. Read More

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http://dx.doi.org/10.2147/IJGM.S177635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336028PMC
January 2019
2 Reads

Mathematical Blueprint of a Mitral Valve.

Semin Thorac Cardiovasc Surg 2019 Jan 8. Epub 2019 Jan 8.

The Mitral Laboratory, Yale School of Medicine, New Haven, Connecticut; Section of Cardiac Surgery, Department of Surgery, Yale School of Medicine, New Haven, Connecticut. Electronic address:

Mathematical modeling tries to simplify understanding and proposes a fundamental mechanism that governs the motion and function of a complex biological system such as a mitral valve (MV) motion which represents a dynamic interplay between papillary muscle (PM) position in the context of left ventricular (LV) shape dynamics. Current therapeutic strategies to intervene on the MV may not have exploited these relationships due to lack of understanding of the interactions. We present a MV 3D mathematical model characterized by LV shape dynamics to understand fundamental working principles of ventriculo-papillary-mitral complex. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10430679183041
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http://dx.doi.org/10.1053/j.semtcvs.2019.01.008DOI Listing
January 2019
19 Reads

Transapical NeoChord mitral valve repair.

Ann Cardiothorac Surg 2018 Nov;7(6):812-820

Department of Cardiology, Thoracic and Vascular Sciences, University of Padua, Padua, Italy.

Transapical off-pump mitral valve repair (MVr) with NeoChord implantation has become widely applied in Europe for patients presenting with severe mitral regurgitation due to leaflet prolapse or flail. The procedure is performed under real-time 2D- and 3D-transesophageal echocardiography (TEE) for both implantation and neochordae tension adjustment allowing real-time monitoring of hemodynamic recovery. Preoperative anatomic and echocardiographic selection criteria, procedure refinement, as well as innovative ex-vivo surgical simulator training have been developed and strategically employed in the past few years, to generate a robust precision-based procedural framework with significantly enhanced operator use, patient safety and clinical outcomes. Read More

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http://www.annalscts.com/article/view/16555/16841
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http://dx.doi.org/10.21037/acs.2018.11.04DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288219PMC
November 2018
8 Reads

Transcatheter mitral valve chord repair.

Ann Cardiothorac Surg 2018 Nov;7(6):731-740

Heart Valve Clinic, University Hospital of Zürich, University of Zürich, Zürich, Switzerland.

The field of mitral valve disease diagnosis and management is rapidly evolving. New understanding of pathophysiology and improvements in the adoption of sophisticated multimodality imaging modalities have led to early diagnosis and to more complex treatment. The most common cause of mitral regurgitation (MR) in the western world is in the primary alteration of the valve, which leads to degenerative leaflet prolapse due to chordal elongation or rupture and annular dilatation. Read More

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http://dx.doi.org/10.21037/acs.2018.09.09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288217PMC
November 2018
4 Reads

Changes in right ventricular longitudinal function: primary mitral and concomitant tricuspid valve repair.

Perfusion 2018 Dec 31:267659118820776. Epub 2018 Dec 31.

1 Department of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.

Objectives:: To evaluate the impact of concomitant tricuspid valve (TV) repair on the right ventricular (RV) function postoperatively and within the 6 months following degenerative mitral valve (MV) repair.

Methods:: The prospective study included 37 patients (mean age 57.32 ± 2. Read More

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http://dx.doi.org/10.1177/0267659118820776DOI Listing
December 2018
18 Reads
1.083 Impact Factor

Echocardiographic findings of cardiovascular involvement in Behçet's disease and post-operative complications after cardiac surgery.

Clin Exp Rheumatol 2018 Nov-Dec;36(6 Suppl 115):103-109. Epub 2018 Dec 13.

Department of Echocardiography, Beijing Anzhen Hospital, Capital Medical University, Beijing, and Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing, China.

Objectives: The aim of this study was to analyse the spectrum of echocardiographic findings in patients with cardiovascular involvement in Behçet's disease (BD) and followed up the post-operative complications.

Methods: We enrolled 26 BD patients who underwent first cardiac surgery in Anzhen Hospital, Beijing, China. Medical records and echocardiographic findings were retrospectively analysed. Read More

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March 2019
7 Reads
2.724 Impact Factor

Role of three dimensional transesophageal echocardiography in predicting mitral regurgitation after percutaneous balloon mitral valvuloplasty.

Indian Heart J 2018 Nov - Dec;70(6):836-842. Epub 2018 Jan 31.

Department of Cardiology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.

Background: Percutaneous balloon mitral valvuloplasty (PBMV) can be complicated with significant mitral regurgitation (MR). We performed a pilot, prospective study to evaluate the role of three dimensional transesophageal echocardiography (3D-TEE) in the prediction of MR after PBMV through mitral valve quantification (MVQ).

Methods: Between October 2014 and October 2016, 37 patients with rheumatic, moderate-to-severe mitral stenosis, referred to the Cath lab of Bab Alshearia University hospitals for PBMV, were divided into two age and sex matched groups. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00194832173051
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http://dx.doi.org/10.1016/j.ihj.2018.01.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306348PMC
January 2019
13 Reads

Inborn Errors of Metabolism: Pseudoxanthoma Elasticum.

Adv Exp Med Biol 2018;1085:187-189

Department of Ophthalmology, Columbia University, Edward S. Harkness Eye Institute, NewYork-Presbyterian Hospital, New York, NY, USA.

Pseudoxanthoma elasticum (PXE) is an autosomal recessive multisystem disorder that involves the skin, GI tract, and heart, as well as the eye. It affects approximately 1 in 50,000 people worldwide and is seen twice as frequently in females as in males. Fundus findings include angioid streaks (Fig. Read More

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http://link.springer.com/10.1007/978-3-319-95046-4_38
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http://dx.doi.org/10.1007/978-3-319-95046-4_38DOI Listing
January 2018
12 Reads

Possible mechanism of late systolic mitral valve prolapse: systolic superior shift of leaflets secondary to annular dilatation that causes papillary muscle traction.

Am J Physiol Heart Circ Physiol 2019 Mar 21;316(3):H629-H638. Epub 2018 Dec 21.

Second Department of Internal Medicine, University of Occupational and Environmental Health, School of Medicine , Kitakyushu , Japan.

Progressive superior shift of the mitral valve (MV) during systole is associated with abnormal papillary muscle (PM) superior shift in late systolic MV prolapse (MVP). The causal relation of these superior shifts remains unclarified. We hypothesized that the MV superior shift is related to augmented MV superiorly pushing force by systolic left ventricular pressure due to MV annular dilatation, which can be corrected by surgical MV plasty, leading to postoperative disappearance of these superior shifts. Read More

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https://www.physiology.org/doi/10.1152/ajpheart.00618.2018
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http://dx.doi.org/10.1152/ajpheart.00618.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459314PMC
March 2019
6 Reads

Catheter ablation versus surgical ablation combined with mitral valve surgery for nonparoxysmal atrial fibrillation in patients with moderate mitral regurgitation.

J Cardiovasc Electrophysiol 2019 Mar 4;30(3):332-338. Epub 2019 Jan 4.

Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.

Objective: There are scarce comparative data on efficacy and procedural safety between radiofrequency catheter ablation (RFCA) and surgical ablation (SA) combined with mitral valve (MV) surgery for patients with nonparoxysmal atrial fibrillation (AF) and moderate mitral regurgitation (MR).

Methods And Results: This single-center, retrospective, and observational study enrolled 155 consecutive patients with nonparoxysmal AF and moderate MR, of which 98 underwent RFCA and 57 underwent SA combined with MV surgery. Circumferential pulmonary vein ablation, bidirectional block of lines, and disappearance of complex fractionated atrial electrograms were the endpoints of RFCA, while pulmonary vein isolation and left and right atrial incisions were performed in SA. Read More

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http://dx.doi.org/10.1111/jce.13821DOI Listing
March 2019
4 Reads
2.958 Impact Factor

MitraClip® Repair in Cardiogenic Shock Due to Acute Mitral Regurgitation: From Near-Death to Walking.

J Heart Valve Dis 2018 Jan;27(1):114-116

Cardiology Department, Cardiovascular Institute (ICCV), Hospital Clínic, IDIBAPS, University of Barcelona, Barcelona, Spain.

A patient with ischemic myocardiopathy who had undergone resynchronization therapy was admitted to the authors' institution with progressive dyspnea. Echocardiography demonstrated a left ventricular ejection fraction (LVEF) of 25%, with a massive mitral regurgitation (MR) secondary to anterior leaflet prolapse and posterior leaflet restriction. Despite intensive medical treatment, the patient developed cardiogenic shock and required mechanical ventilation, inotropic support and intra-aortic balloon pumping. Read More

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January 2018
4 Reads

Intermediate-term outcomes of our original multiple-knot technique using ePTFE sutures for anterior mitral leaflet prolapse.

Surg Today 2019 Apr 6;49(4):350-356. Epub 2018 Dec 6.

Department of Cardiovascular Surgery, Osaka Rosai Hospital, 1179-3, Nagasone-cho, Kita-ku, Sakai, Osaka, Japan.

Purpose: To define the outcomes of our original simple chordal replacement technique using ePTFE sutures for mitral regurgitation.

Methods: Between January, 2004 and March, 2014, 38 patients underwent mitral valve repair using our chordal replacement technique for anterior leaflet prolapse. The mitral regurgitation was caused by degenerative disease in 34 patients and infective endocarditis in 4 patients. Read More

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http://dx.doi.org/10.1007/s00595-018-1745-5DOI Listing
April 2019
4 Reads

Arrhythmic Mitral Valve Prolapse: JACC Review Topic of the Week.

J Am Coll Cardiol 2018 Dec;72(23 Pt A):2904-2914

Helmsley Electrophysiology Center, Icahn School of Medicine at Mount Sinai, New York, New York.

There is an increasing awareness of the association between mitral valve prolapse and sudden cardiac death. There are several clinical risk factors associated with an increased risk of mitral valve prolapse-related sudden cardiac death, most of which can be evaluated with noninvasive diagnostic modalities. For example, characteristic changes on the electrocardiogram (T-wave inversions in the inferior leads), complex ventricular ectopy, a spiked configuration of the lateral annular velocities by echocardiography, and evidence of myocardial fibrosis by cardiac magnetic resonance imaging have all been implicated as markers of risk. Read More

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http://dx.doi.org/10.1016/j.jacc.2018.09.048DOI Listing
December 2018
2 Reads

Genome-wide association study of degenerative mitral valve disease in Maltese dogs.

J Vet Sci 2019 Jan;20(1):63-71

Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Seoul 05030, Korea.

Genome-wide association study (GWAS) is a powerful tool for identifying the genetic causes of various diseases. This study was conducted to identify genomic variation in Maltese dog genomes associated with degenerative mitral valve disease (DMVD) development and to evaluate the association of each biological condition with DMVD in Maltese dogs. DNA was extracted from blood samples obtained from 48 Maltese dogs (32 with DMVD and 16 controls). Read More

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http://dx.doi.org/10.4142/jvs.2019.20.1.63DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351756PMC
January 2019
13 Reads

Infective endocarditis complicated with nonobstructive ST elevation myocardial infarction related to septic embolism with intracranial hemorrhage: A case report.

Medicine (Baltimore) 2018 Nov;97(48):e13089

Division of Cardiology, Department of Internal Medicine, Kaohsiung Medical University Hospital.

Rationale: Infective endocarditis (IE) complicated with obstructive ST elevation myocardial infarction (STEMI) has been reported in the literature and which were mostly related to coronary artery embolism, obstruction, or compression. However, there has been no reported case discussing about IE complicated with nonobstructive STEMI.

Patient Concerns: In this report, we report a 38-year-old female suffering from intermittent fever and was later diagnosed as IE. Read More

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http://dx.doi.org/10.1097/MD.0000000000013089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283201PMC
November 2018
19 Reads
5.723 Impact Factor

A Case of Single Atrium, Mitral Valve Prolapse Spontaneously - Closed Inlet VSD with Polydactyly.

Mymensingh Med J 2018 Oct;27(4):894-897

Dr Ranjan Kumar Majumder, Department of Cardiology, Kumudini Women's Medical College, Mirzapur, Tangail, Bangladesh.

Single Atrium is a complex cardiac anomaly and generally a component of certain congenital syndromes. It is extremely rare for SA to be observed as an isolated defect. We report here a 14 year-old male patient with SA with MVP with spontaneously-closed inlet-VSD with polydactyly. Read More

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October 2018
2 Reads

Mitral Valve Prolapse and Sudden Cardiac Death: A Systematic Review.

J Am Heart Assoc 2018 Dec;7(23):e010584

1 Department of Cardiology Austin Health University of Melbourne Melbourne Australia.

Background The relationship between mitral valve prolapse ( MVP ) and sudden cardiac death ( SCD ) remains controversial. In this systematic review, we evaluate the relationship between isolated MVP and SCD to better define a potential high-risk subtype. In addition, we determine whether premortem parameters could predict SCD in patients with MVP and the incidence of SCD in MVP . Read More

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http://dx.doi.org/10.1161/JAHA.118.010584DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405538PMC
December 2018
5 Reads

Mitral valve prolapse.

Expert Rev Cardiovasc Ther 2018 Nov 28. Epub 2018 Nov 28.

a Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust , London , UK.

Introduction: Mitral valve prolapse is a common valve pathology with a spectrum of disease from isolated prolapse to myxomatous, multi-scallop Barlow's disease. The main complications relate to progression of mitral regurgitation, endocarditis, sudden death and stroke. The timing of intervention in patients with asymptomatic severe mitral regurgitation is controversial. Read More

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http://dx.doi.org/10.1080/14779072.2019.1553619DOI Listing
November 2018
8 Reads

Beating heart porcine high-fidelity simulator for the training of edge-to-edge mitral valve repair.

Multimed Man Cardiothorac Surg 2018 Nov 16;2018. Epub 2018 Nov 16.

Department of Cardiac Surgery Medical University of Innsbruck Innsbruck, Austria.

Transcatheter treatment of structural heart disease is becoming an everyday reality for an increasing number of surgeons, and effective training modalities for basic guide-wire skills, catheter handling, and periprocedural imaging are of growing relevance. In this video tutorial we present a beating-heart porcine model used as a high-fidelity training simulator for transcatheter cardiac valve procedures.  We demonstrate a complete transcatheter edge-to-edge mitral valve repair procedure, including periprocedural imaging, clip deployment, and quality control. Read More

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http://dx.doi.org/10.1510/mmcts.2018.045DOI Listing
November 2018
16 Reads

New insights into mitral heart valve prolapse after chordae rupture through fluid-structure interaction computational modeling.

Sci Rep 2018 Nov 23;8(1):17306. Epub 2018 Nov 23.

The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA.

Mitral valve (MV) dynamics depends on a force balance across the mitral leaflets, the chordae tendineae, the mitral annulus, the papillary muscles and the adjacent ventricular wall. Chordae rupture disrupts the link between the MV and the left ventricle (LV), causing mitral regurgitation (MR), the most common valvular disease. In this study, a fluid-structure interaction (FSI) modeling framework is implemented to investigate the impact of chordae rupture on the left heart (LH) dynamics and severity of MR. Read More

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http://www.nature.com/articles/s41598-018-35555-5
Publisher Site
http://dx.doi.org/10.1038/s41598-018-35555-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251907PMC
November 2018
12 Reads

Measuring chordae tension during transapical neochordae implantation: Toward understanding objective consequences of mitral valve repair.

J Thorac Cardiovasc Surg 2018 Oct 17. Epub 2018 Oct 17.

Department of Adult Cardiac Surgery, Hôpital cardiologique Louis Pradel, Lyon Medical School, Bron, France.

Objectives: Complex structure of mitral valve and its central position in the heart limit assessment of mitral function to standardized calculated parameters assessed using medical imaging (echocardiography). Novel techniques, which allow mitral valve repair (MVr) in a beating heart, offer the opportunity for innovative objective assessment in physiologic and pathologic conditions. We report, to our knowledge, the first data of real-time chordal tension measurement during a transapical neochordae implantation. Read More

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http://dx.doi.org/10.1016/j.jtcvs.2018.10.029DOI Listing
October 2018
14 Reads