78,102 results match your criteria Mitral Valve


Successful bridge to transplantation with long-term support using Berlin heart EXCOR in a child with failing Fontan.

Gen Thorac Cardiovasc Surg 2022 Jun 28. Epub 2022 Jun 28.

Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Yamadaoka, 2-2, Suita, Osaka, 565-0871, Japan.

A 2-year-old girl underwent the Fontan operation for aortic valve stenosis, mitral valve stenosis, a hypo-plastic left ventricle, and a non-compacted right ventricle. The patient's cardiac function reduced gradually thereafter, mainly due to systemic ventricular dysfunction. A Berlin Heart EXCOR (BHE) ventricular assist device with a 10-mL pump was implanted at 4 years of age. Read More

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Prevalence of cardiac valvar abnormalities in children and young people with autosomal dominant polycystic kidney disease.

Pediatr Nephrol 2022 Jun 28. Epub 2022 Jun 28.

Department of Paediatric Nephrology, Evelina London Children's Hospital, Guys & St Thomas NHS Foundation Trust, Westminster Bridge Road, London, SE1 7EH, UK.

Background: Valvar abnormalities in children and adults with autosomal dominant polycystic kidney disease (ADPKD) have previously been reported as a frequent occurrence. Mitral valve prolapse (MVP), in particular, has been reported in almost one-third of adult patients and nearly 12% of children with ADPKD. Our objective in this study was to establish the prevalence of valvar abnormalities in a large, contemporary series of children and young people (CYP) with ADPKD. Read More

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Fatal Autonomic Dysfunction Due to Guillain-Barré Syndrome After Cardiac Surgery.

Tex Heart Inst J 2022 May;49(3)

Department of Cardiovascular Surgery, Bezmialem Vakif University, Istanbul, Turkey.

Guillain-Barré syndrome, a rare peripheral neuropathy, appears to occur more often in patients who have recently undergone surgery than in the general population. However, the pathophysiologic relationship between surgery and Guillain-Barré syndrome is elusive. Few cases of Guillain-Barré syndrome after cardiac surgery have been reported. Read More

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KMT2D-NOTCH Mediates Coronary Abnormalities in Hypoplastic Left Heart Syndrome.

Circ Res 2022 Jun 28:101161CIRCRESAHA122320783. Epub 2022 Jun 28.

Perinatal Institute, Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, OH (Z.Y., Z.L., V.P.-G., M.G., Y.M., M.G.).

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Commentary on the Enigma of Small Vessel Disease in Hypertrophic Cardiomyopathy: Is Invasive Assessment of Microvascular Resistance a Novel Independent Predictor of Prognosis?

Cardiovasc Pathol 2022 Jun 24:107448. Epub 2022 Jun 24.

Department of Pathology and Laboratory Medicine, The University of Texas Health Science Center at Houston (UTHealth), Houston, Texas, USA.

The key pathophysiological features in hypertrophic cardiomyopathy are ventricular hypertrophy, diastolic dysfunction and abnormalities in the mitral valve apparatus, but coronary microvascular dysfunction and ischemia have also been described. The small vessel disease changes could be reflected in the invasive measurement of the index of microvascular resistance, with prognostic potential. Read More

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Echocardiographic evaluation of total anomalous pulmonary venous connection: Comparison of obstructed and unobstructed type.

Medicine (Baltimore) 2022 Jun 24;101(25):e29552. Epub 2022 Jun 24.

Department of Radiology, Hunan Children's Hospital, University of South China, Changsha, China.

Abstract: This study aims to compare the differences between obstructed and unobstructed total anomalous pulmonary venous connection (TAPVC) using echocardiography, and to evaluate the clinical and echocardiographic parameters associated with pulmonary venous obstruction (PVO).We conducted a retrospective study of 70 patients with TAPVC between 2014 and 2019. The morphologic and hemodynamic echocardiographic parameters of patients were observed and measured, and the parameters between obstructed and unobstructed TAPVC were compared. Read More

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Surgical Outcomes in Children With Partial and Transitional Atrioventricular Septal Defect.

World J Pediatr Congenit Heart Surg 2022 Jul;13(4):451-457

Department of Cardiovascular Surgery, The Heart Institute of Japan, Tokyo, Japan.

Background: This study aimed to evaluate the long-term outcomes of partial and transitional atrioventricular septal defect repair, focusing on left atrioventricular valve reoperation.

Methods: We conducted a retrospective review of 104 children who underwent partial or transitional atrioventricular septal defect repair between August 1983 and January 2021. The major outcomes included patient survival and left atrioventricular valve reoperation. Read More

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Intramural Esophageal Hematoma Mimicking Acute Coronary Syndrome: Complication of Warfarin Use in a Mechanical Heart Valve Patient.

Case Rep Med 2022 15;2022:5636989. Epub 2022 Jun 15.

Shohada-Ye-Tajrish Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

A 59-year-old female with a history of mitral valve replacement presented to emergency department, complaining of sudden-onset retrosternal chest pain since 4 hours ago. Electrocardiogram, laboratory tests, and computed tomography (CT) angiography of aorta were performed and ruled out aortic dissection and cardiovascular events. However, new complaint of odynophagia, dysphagia, and incidental findings in CT angiography proposed esophageal pathologies. Read More

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SARS-CoV-2 Associated Pediatric Inflammatory Multisystem Syndrome With a High Prevalence of Myocarditis - A Multicenter Evaluation of Clinical and Laboratory Characteristics, Treatment and Outcome.

Front Pediatr 2022 10;10:896252. Epub 2022 Jun 10.

Department of Pediatrics, Division of Pediatric Cardiology, Pediatric Heart Centre, Medical University of Vienna, Vienna, Austria.

Introduction: comprises a new disease entity having emerged after the COVID-19 outbreak in 2019.

Materials And Methods: For this multicenter, retrospective study children between 0 and 18 years with PIMS-TS between March 2020 and May 2021 were included, before availability of vaccination for children. Frequent SARS-CoV-2 variants at that period were the wildtype virus, alpha, beta and delta variants. Read More

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Towards Real-time pose estimation of the Mitral Valve Robot under C-arm X-ray Fluoroscopy.

IEEE Trans Med Robot Bionics 2021 Nov 22;3(4):928-935. Epub 2021 Oct 22.

Medical Robotics and Automation (RoboMed) Laboratory, Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA 30332 USA.

Mitral regurgitation (MR) is a condition caused by a deformity in the mitral valve leading to the backflow of blood into the left atrium. MR can be treated through a minimally invasive procedure and our lab is currently developing a robot that could potentially be used to treat MR. The robot would carry a clip that latches onto the valve's leaflets and closes them to minimize leakage. Read More

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November 2021

tricuspid valve infective endocarditis.

Proc (Bayl Univ Med Cent) 2022 7;35(4):522-523. Epub 2022 Apr 7.

Department of Cardiology, State University of New York Upstate Medical University, Syracuse, New York.

is an alpha-hemolytic, gram-positive coccus that is responsible for 54/1,000,000 cases of all urinary tract infections. Risk factors include male gender, advanced age, and genitourinary tract abnormalities. It has often been misidentified as or due to its morphological similarities. Read More

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Analysis of Dysfunctioning Mechanical Prostheses Excised from the Mitral Valve Position.

Am J Cardiol 2022 Jun 22. Epub 2022 Jun 22.

Baylor Scott & White Heart and Vascular Institute.

Described herein are findings in 16 patients who had their dysfunctioning mechanical prostheses in the mitral valve position replaced. The mechanical prostheses had been in place from 2 to 157 months (mean 80). All but 1 patient had the mechanical prosthesis excised because of prosthetic stenosis or regurgitation or both secondary to prosthetic thrombus (despite warfarin therapy) on cloth-ring "pannus" overlaying the orifice or parabasilar detachment ("leak"). Read More

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Regional left ventricular endocardial strains estimated from low-dose 4DCT: comparison with cardiac magnetic resonance feature tracking.

Med Phys 2022 Jun 25. Epub 2022 Jun 25.

Department of Bioengineering, University of California San Diego, La Jolla, California, USA.

Background: Estimates of regional left ventricular (LV) strains provide additional information to global function parameters such as ejection fraction (EF) and global longitudinal strain (GLS), and are more sensitive in detecting abnormal regional cardiac function. The accurate and reproducible assessment of regional cardiac function has implications in the management of various cardiac diseases such as heart failure, myocardial ischemia, and dyssynchrony.

Purpose: To develop a method that yields highly reproducible, high-resolution estimates of regional endocardial strains from 4DCT images. Read More

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Mitral annular calcification: The incremental diagnostic value of 3D transesophageal echocardiography.

Echocardiography 2022 Jun 24. Epub 2022 Jun 24.

Medical College of Georgia, Augusta University, Augusta, Georgia, USA.

Three-dimensional (3D) echocardiography is an important tool in the evaluation of mitral valve anatomy. We illustrate a case of a 67-year-old female who was admitted for non-ST-elevation myocardial infarction (NSTEMI) and underwent two-vessel coronary artery bypass grafting for surgical disease. Her two-dimensional (2D) echocardiographic images intraoperatively demonstrated a mass on the posterior mitral valve leaflet which created a diagnostic challenge; 3D transesophageal imaging was crucial in identifying the true nature of the pathology to be mitral annular calcification with supra-annular extension. Read More

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Stage-based approach to predict left ventricular reverse remodeling after mitral repair.

Clin Cardiol 2022 Jun 24. Epub 2022 Jun 24.

Division of Cardiac Surgery, Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, Ontario, Canada.

Background: Although predictors of reverse left ventricular (LV) remodeling postmitral valve repair are critical for guiding perioperative decision-making, there remains a paucity of randomized, prospective data to support the criteria that potential predictor variables must meet.

Methods And Results: The CAMRA CardioLink-2 randomized trial allocated 104 patients to either leaflet resection or preservation strategies for mitral repair. The correlation of indexed left ventricular end-systolic volume (LVESVI), indexed left ventricular end-diastolic volume (LVEDVI), and left ventricular ejection fraction (LVEF) were tested with univariate analysis and subsequently with multivariate analysis to determine independent predictors of reverse remodeling at discharge and at 12 months postoperatively. Read More

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50 anniversary of Ionescu's pericardial heart valve concept.

Br J Cardiol 2021 2;28(3):28. Epub 2021 Jun 2.

Locum Cardiac Surgeon University Hospital Southampton, Tremona Road, Southampton, SO16 6YD.

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Transcatheter mitral valve intervention.

Br J Cardiol 2021 30;28(4):51. Epub 2021 Nov 30.

Consultant Cardiologist Royal Brompton and Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, Hill End Road, Harefield, UB9 6JH.

Mitral regurgitation is a common valvular heart disorder increasing with age. Many patients are ineligible for mitral valve surgery due to their age and other comorbidities. Left untreated, patients develop severe disease with a poor prognosis. Read More

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November 2021

Demonstration of Use of a Novel 3D Printed Simulator for Mitral Valve Transcatheter Edge-to-Edge Repair (TEER).

Materials (Basel) 2022 Jun 17;15(12). Epub 2022 Jun 17.

Institute of Cardiovascular Science, University College London, London WC1E 6BT, UK.

Mitral regurgitation is a common valvular disorder. Transcatheter edge-to-edge repair (TEER) is a minimally invasive technique which involves holding together the middle segments of the mitral valve leaflets, thereby reducing regurgitation. To date, MitraClip™ is the only Food and Drug Administration (FDA)-approved device for TEER. Read More

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Change in Lung Fluid Volume during Exercise in Patients with Exercise-Induced Mitral Regurgitation.

Medicina (Kaunas) 2022 May 28;58(6). Epub 2022 May 28.

Second Department of Internal Medicine, University of Toyama, Toyama 930-0194, Japan.

Exercise-induced mitral regurgitation (MR) can be diagnosed during stress echocardiography testing. Remote dielectric sensing (ReDS) is a noninvasive electromagnetic-based modality to measure lung fluid levels. The change in lung fluid levels in patients with MR during stress echocardiography remains unknown. Read More

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A Rescue Use of ECPELLA for Sepsis-Induced Cardiogenic Shock Followed by Mitral Valve Replacement.

Medicina (Kaunas) 2022 May 25;58(6). Epub 2022 May 25.

The Second Department of Internal Medicine, University of Toyama, Toyama 930-0194, Japan.

The use of veno-arterial extracorporeal membrane oxygenation (ECMO) in patients with sepsis-induced cardiogenic shock has been reported, but the clinical implication of the Impella percutaneous axial-flow left ventricular assist device for such patients remains unknown. We had a 37-year-old man with septic shock and severely reduced cardiac function. Veno-arterial ECMO and concomitant Impella CP support ameliorated his end-organ dysfunction and achieved cardiac recovery, whereas severe mitral valve regurgitation due to chordal rupture developed later. Read More

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Ultrasound-Guided PECS II + Serratus Plane Fascial Blocks Are Associated with Reduced Opioid Consumption and Lengths of Stay for Minimally Invasive Cardiac Surgery: An Observational Retrospective Study.

Life (Basel) 2022 May 28;12(6). Epub 2022 May 28.

Department of Neurosciences, Institute of Human Anatomy, University of Padova, 35121 Padova, Italy.

This study tested the hypothesis that pectoralis II (PECS II) + serratus plane blocks would reduce opioid consumption and improve outcomes compared with standard practice in minimally invasive cardiac surgery. A retrospective and observational study was realized in the intensive care unit (ICU) setting of "ICLAS GVM, Istitituto Clinico Ligure Alta Specialità, (Rapallo, Italy)", including adult patients who underwent right minithoracotomy for replacement/plastic aortic, mitral and tricuspid valve or atrial myxoma resection in cardiac surgery. Seventy-eight patients were extracted by the database and divided into two groups. Read More

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Review of Contemporary Invasive Treatment Approaches and Critical Appraisal of Guidelines on Hypertrophic Obstructive Cardiomyopathy: State-of-the-Art Review.

J Clin Med 2022 Jun 14;11(12). Epub 2022 Jun 14.

Department for the Treatment and Study of Cardiothoracic Diseases and Cardiothoracic Transplantation, IRCCS-ISMETT, 90127 Palermo, Italy.

Background: Hypertrophic obstructive cardiomyopathy (HOCM) is a heterogeneous disease with different clinical presentations, albeit producing similar dismal long-term outcomes if left untreated. Several approaches are available for the treatment of HOCM; e.g. Read More

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Transcatheter Mitral Valve Repair or Replacement: Competitive or Complementary?

J Clin Med 2022 Jun 13;11(12). Epub 2022 Jun 13.

Department of Cardiovascular Surgery, University Medical Center Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany.

Over the last two decades, transcatheter devices have been developed to repair or replace diseased mitral valves (). Transcatheter mitral valve repair () devices have been proven to be efficient and safe, but many anatomical structures are not compatible with these technologies. The most significant advantage of transcatheter mitral valve replacement () over transcatheter repair is the greater and more reliable reduction in mitral regurgitation. Read More

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Fourteen-Year Temporal Trends in Patients Hospitalized for Mitral Regurgitation: The Increasing Burden of Mitral Valve Prolapse in Men.

J Clin Med 2022 Jun 8;11(12). Epub 2022 Jun 8.

Department of Non-Communicable Diseases, Santé Publique France, French Public Health Agency, 94410 Saint-Maurice, France.

Mitral regurgitation (MR) is the second most common valvular heart disease in Europe. The aging of the population and the increase in post-infarction survival could increase the prevalence of MR. To estimate the burden of patients hospitalized for MR in France in 2019 and temporal trends by etiology and sex from 2006 to 2020, we selected all patients hospitalized for MR using the national hospital database. Read More

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Experience of Combined Procedure during Percutaneous LAA Closure.

J Clin Med 2022 Jun 8;11(12). Epub 2022 Jun 8.

Institut Universitaire de Cardiologie et de Pneumologie de Québec, Quebec City, QC G1V 4G5, Canada.

Introduction: Percutaneous left atrial appendage closure (LAAC) is an alternative to oral anticoagulants (OAC) in patients with non-valvular atrial fibrillation (AF) and contraindication to long-term OAC. Combined strategy with percutaneous LAAC at the same time of other cardiac structural or electrophysiological procedures has emerged as an alternative to a staged strategy.

Aim: To describe our experience with combined LAAC procedures using Watchman™ devices. Read More

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Early Postoperative Immunothrombosis of Bioprosthetic Mitral Valve and Left Atrium: A Case Report.

Int J Mol Sci 2022 Jun 16;23(12). Epub 2022 Jun 16.

Department of Experimental Medicine, Research Institute for Complex Issues of Cardiovascular Diseases, 650002 Kemerovo, Russia.

A 72-year-old female patient with mixed rheumatic mitral valve disease and persistent atrial fibrillation underwent mitral valve replacement and suffered from a combined thrombosis of the bioprosthetic valve and the left atrium as soon as 2 days post operation. The patient immediately underwent repeated valve replacement and left atrial thrombectomy. Yet, four days later the patient died due to the recurrent prosthetic valve and left atrial thrombosis which both resulted in an extremely low cardiac output. Read More

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Biglycan Is a Novel Mineralocorticoid Receptor Target Involved in Aldosterone/Salt-Induced Glomerular Injury.

Int J Mol Sci 2022 Jun 15;23(12). Epub 2022 Jun 15.

Cardiovascular Translational Research, Navarrabiomed (Miguel Servet Foundation), Instituto de Investigación Sanitaria de Navarra (IdiSNA), 31008 Pamplona, Spain.

The beneficial effects of mineralocorticoid receptor (MR) antagonists (MRAs) for various kidney diseases are established. However, the underlying mechanisms of kidney injury induced by MR activation remain to be elucidated. We recently reported aldosterone-induced enhancement of proteoglycan expression in mitral valve interstitial cells and its association with fibromyxomatous valvular disorder. Read More

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Echocardiography in Prone Positioned Critically Ill Patients: A Wealth of Information from a Single View.

Diagnostics (Basel) 2022 Jun 14;12(6). Epub 2022 Jun 14.

Department of Anesthesia, Intensive Care Unit and Pain Therapy, IRCCS Humanitas Clinical and Research Center, 20089 Milan, Italy.

In critically ill patients, standard transthoracic echocardiography (TTE) generally does not facilitate good image quality during mechanical ventilation. We propose a prone-TTE in prone positioned patients, which allows clinicians to obtain a complete apical four-chamber (A-4-C) view. A basic cardiac assessment can be performed in order to evaluate right ventricle function and left ventricle performance, even measuring objective parameters, i. Read More

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Altered Transmission of Cardiac Cycles to Ductus Venosus Blood Flow in Fetal Growth Restriction: Why Ductus Venosus Reflects Fetal Circulatory Changes More Precisely.

Diagnostics (Basel) 2022 Jun 4;12(6). Epub 2022 Jun 4.

Department of Obstetrics and Gynecology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahimachi Abeno-ku Osaka, Osaka 545-8585, Japan.

We aimed to investigate the relation between the time intervals of the flow velocity waveform of ductus venosus (DV-FVW) and cardiac cycles. We defined Delta A as the difference in the time measurements between DV-FVW and cardiac cycles on the assumption that the second peak of ductus venosus (D-wave) starts simultaneously with the opening of the mitral valve (MV). As well, we defined Delta B as the difference of the time measurements between DV-FVW and cardiac cycles on the assumption that the D-wave starts simultaneously with the closure of the aortic valve (AV). Read More

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