24,031 results match your criteria Mitral Stenosis


Intracardiac thrombus in a patient with mitral bioprosthesis and atrial fibrillation treated with direct oral anticoaugulant: A case report.

Medicine (Baltimore) 2021 Jun;100(23):e26137

IRCCS Bonino Pulejo of Messina, Cardiology Unit.

Rationale: Atrial fibrillation (AF) is the most common cardiac arrhythmia and is associated with increased morbidity, especially stroke and heart failure. There is also increasing awareness that atrial fibrillation is a major cause of embolic events which in 75% of cases are complicated by cerebrovascular accidents.

Patient Concerns: A 50-year-old woman with mitral bioprosthesis under warfarin for nonvalvular atrial fibrillation was referred to our Coronary Intensive Care Unit due to acute myocardial infarction without evidence of significant coronary artery stenosis. Read More

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Transcatheter Versus Surgical Aortic Valve Replacement in Young, Low-Risk Patients With Severe Aortic Stenosis.

JACC Cardiovasc Interv 2021 Jun;14(11):1169-1180

Section of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, USA. Electronic address:

Transcatheter aortic valve replacement (TAVR) is approved for all patient risk profiles and is an option for all patients irrespective of age. However, patients enrolled in the low- and intermediate-risk trials were in their 70s, and those in the high-risk trials were in their 80s. TAVR has never been systematically tested in young (<65 years), low-risk patients. Read More

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Does patent foramen ovale presence procure favourable outcomes in patients with severe rheumatic mitral stenosis?

Int J Cardiovasc Imaging 2021 Jun 9. Epub 2021 Jun 9.

Cardiology Department, Mehmet Akif Ersoy Thoracic And Cardiovascular Surgery Training and Research Hospital, University Of Health Sciences Istanbul, Turgut Ozal Bulvarı no:11, 34303, Istanbul, Küçükçekmece, Turkey.

Mitral stenosis (MS) is tolerated for an extended period in patients with atrial septal defect (ASD) known as Lutembacher syndrome due to depressurizing effect. In a similar way, patients with patent foramen ovale (PFO) may have clinical benefits in severe MS. We aim to evaluate the clinical effects of PFO in rheumatic MS. Read More

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Cardiac Involvement in Facioscapulohumeral Muscular Dystrophy (FSHD).

Front Neurol 2021 24;12:668180. Epub 2021 May 24.

Department of Neurology, Mayo Clinic, Rochester, MN, United States.

Facioscapulohumeral muscular dystrophy (FSHD) is one of the most common muscular dystrophies and predominantly affects facial and shoulder girdle muscles. Previous case reports and cohort studies identified minor cardiac abnormalities in FSHD patients, but their nature and frequency remain incompletely characterized. We reviewed cardiac, neurological and genetic findings of 104 patients with genetically confirmed FSHD. Read More

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Feasibility and Safety of High-Risk Percutaneous Coronary Intervention Without Mechanical Circulatory Support.

Circ Cardiovasc Interv 2021 Jun 7:CIRCINTERVENTIONS120009960. Epub 2021 Jun 7.

Section of Interventional Cardiology, MedStar Washington Hospital Center, DC (N.K., T.R., C.Z., C.S., E.S., Y.C., A.M., J.P.W., B.C., H.H., I.B.-D., N.L.B., L.S., R.W.).

Background: Recommendations to broaden the use of mechanical circulatory support (MCS) for high-risk percutaneous coronary intervention (PCI) remain controversial with the absence of robust evidence from randomized clinical trials and the risk of device-related complications. This investigation examined whether performing high-risk PCI without elective MCS is feasible and safe.

Methods: We performed a single-center, retrospective analysis for patients meeting contemporary high-risk PCI criteria as defined by the Interventional Council of the American College of Cardiology. Read More

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The matryoshka procedure.

J Card Surg 2021 Jun 6. Epub 2021 Jun 6.

Department of Cardiovascular Sciences, European Hospital, Rome, Italy.

We present the case of a 73-year-old male patient undergoing a modified Bentall-DeBono procedure in 2015 due to aortic stenosis and aortic aneurism involving the root. A bioprosthetic stented conduit made with a stented Edwards Perimount 21-mm bioprosthesis and a Vascutek Valsalva 28-mm Dacron graft was implanted along with a mitral annuloplasty. Five years later, due to early degeneration of the bioprosthesis and a progression of the mitral disease, he underwent a second surgical procedure where a Medtronic Mosaic 27-mm valve prosthesis was implanted in mitral position and a sutureless Livanova Perceval 23-mm valve in aortic position. Read More

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Comparison of Transcatheter and Open Mitral Valve Repair Among Patients With Mitral Regurgitation.

Mayo Clin Proc 2021 06;96(6):1522-1529

Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT; Center for Outcomes Research and Evaluation, New Haven, CT. Electronic address:

In 2013, the Food and Drug Administration approved the first transcatheter mitral valve repair (TMVr) device for degenerative mitral regurgitation for patients at prohibitive surgical risk. To better understand contemporary utilization trends and outcomes, we reviewed hospitalizations, identified using International Classification of Diseases, Ninth Revision and International Classification of Diseases, Tenth Revision codes, in which the patient underwent TMVr or mitral valve repair (MVr) with a diagnosis of mitral regurgitation, without stenosis, from the National (Nationwide) Inpatient Sample from 2014 to 2017. We included 10,020 hospitalizations in which the patient underwent TMVr and 5845 in which the patient underwent MVr and assessed trends in demographic characteristics, patient comorbidities, total hospital charges, and outcomes. Read More

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Refined Staging Classification of Cardiac Damage Associated with Aortic Stenosis and Outcomes after Transcatheter Aortic Valve Implantation.

Eur Heart J Qual Care Clin Outcomes 2021 Jun 4. Epub 2021 Jun 4.

Department of Cardiology, Inselspital, University of Bern, Bern, Switzerland.

Aims: A new staging classification of aortic stenosis (AS) characterizing the extent of cardiac damage was established and validated in patients undergoing transcatheter aortic valve implantation (TAVI). We aimed to validate an updated classification system in patients undergoing TAVI.

Methods And Results: In a prospective TAVI registry, AS patients were categorized into the following stages: no cardiac damage (Stage 0), left ventricular damage (Stage 1), left atrial or mitral valve damage (Stage 2), pulmonary vasculature or tricuspid valve damage (Stage 3), or right ventricular (RV) damage or low-flow state (Stage 4). Read More

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Rapid decline in cardiac function in diabetic patients with calcified coronary artery disease undergoing hemodialysis: two case reports.

BMC Cardiovasc Disord 2021 Jun 3;21(1):271. Epub 2021 Jun 3.

Department of Cardiovascular Surgery, Juntendo University, 2-1-1, Bunkyo-ku, Tokyo, 113-8421, Japan.

Background: Clinical symptoms of patients on dialysis do not match the signs of coronary disease progression, making the prediction of the true progression of their medical condition in clinical settings difficult. Emergency and concomitant surgeries are significant risk factors of mortality following open-heart surgery in patients on hemodialysis.

Case Presentation: We report two cases of successful coronary artery bypass grafting (CABG) in patients on dialysis with a history of cardiac surgery. Read More

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Effects of Modified Simultaneous Unipolar Saline-Irrigated Radiofrequency Ablation in Patients with Atrial Fibrillation Combined with Mitral Valve Disease.

Int J Gen Med 2021 26;14:1547-1553. Epub 2021 May 26.

Department of Cardiovascular Surgery, General Hospital of Ningxia Medical University, Yinchuan, 750004, People's Republic of China.

Objective: To investigate the therapeutic effects of a modified simultaneous unipolar saline-irrigated radiofrequency ablation by intracardiac operation under direct vision in patients with mitral valve diseases combined with atrial fibrillation (AF).

Methods: A total of 168 patients with mitral valve diseases combined with AF who underwent unipolar saline-irrigated radiofrequency ablation modified maze procedures were enrolled and divided into the mitral stenosis (MS) group (n = 87) and the mitral insufficiency (MI) group (n = 81).

Results: Those with a left atrium diameter (LAD) < 55 mm had a better cardioversion effect during the mid-term post-operation than those with a LAD ≥ 55 mm (P < 0. Read More

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Diabetic microvascular complications are associated with reduced global longitudinal strain independent of atherosclerotic coronary artery disease in asymptomatic patients with diabetes mellitus: a cross-sectional study.

BMC Cardiovasc Disord 2021 Jun 2;21(1):269. Epub 2021 Jun 2.

Cardiovascular Research Unit, Odense University Hospital Svendborg, Baagøes Allé 15, 5700, Svendborg, Denmark.

Background: Reduced left ventricular function, assessed by global longitudinal strain (GLS), is sometimes observed in asymptomatic patients with diabetes mellitus (DM) and is often present in patients with diabetes-related microvascular complications. Our aim was to assess the association between microvascular complications, coronary artery plaque burden (PB) and GLS in asymptomatic patients with DM and non-obstructive coronary artery disease (CAD).

Methods: This cross-sectional study included patients with DM without any history, symptoms or objective evidence of obstructive CAD. Read More

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Cardiac Manifestations in a Group of Romanian Patients with Gaucher Disease Type 1 (a Monocentric Study).

Diagnostics (Basel) 2021 May 29;11(6). Epub 2021 May 29.

Faculty of Medicine, "Iuliu Hațieganu" University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.

Gaucher disease (GD), one of the most common lysosomal disorders, is characterised by clinical heterogeneity. Cardiac involvement is rare and refers to pulmonary hypertension (PH), valvular abnormalities and myocardial infiltrative damage. The aim of this study was to evaluate cardiac involvement in a group of Romanian GD patients. Read More

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The assessment of mitral valve disease: a guideline from the British Society of Echocardiography.

Echo Res Pract 2021 May 1. Epub 2021 May 1.

B Rana, Cardiology, Hammersmith Hospitals NHS Trust, London, United Kingdom of Great Britain and Northern Ireland.

Mitral valve disease is common. Mitral regurgitation is the second most frequent indication for valve surgery in Europe and despite the decline of rheumatic fever in western societies, mitral stenosis of any aetiology is a regular finding in all echo departments. Mitral valve disease is therefore one of the most common pathologies encountered by echocardiographers, as both a primary indication for echocardiography and a secondary finding when investigating other cardiovascular disease processes. Read More

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Outcome of Peripartum Anesthesia in Women with Valvular Disease.

Rom J Anaesth Intensive Care 2020 Jul 10;27(1):11-14. Epub 2020 Aug 10.

Department of Anesthesiology, Perioperative Medicine and Pain Treatment, Shaare Zedek Medical Center, affiliated with Hebrew University, Jerusalem, Israel.

Objective: Maternal heart disease is one of the major causes for mortality among parturients. In our study, we surveyed 220 patients with different valvular disorders who gave birth in our medical center in the years 2012-2018. The aim of this study was to characterize various valvular pathologies and compare the results of different anesthetic approaches. Read More

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Unilateral Diffuse Alveolar Hemorrhage Due to Selective Directionality of Mitral Regurgitant Jet in a Patient With Severe Aortic Stenosis.

Cureus 2021 Apr 27;13(4):e14714. Epub 2021 Apr 27.

Pulmonary and Critical Care Medicine, Ozarks Medical Center, West Plains, USA.

Diffuse alveolar hemorrhage (DAH) in cardiac diseases results from pulmonary capillary stress failure due to pulmonary venous hypertension. The most common cardiac causes of DAH are heart failure and mitral valvular disease. Patients typically manifest with hemoptysis, radiologic chest abnormalities, and anemia. Read More

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Clinical outcomes after implantation of a sutureless aortic bioprosthesis with concomitant mitral valve surgery: the SURE-AVR registry.

J Cardiothorac Surg 2021 May 30;16(1):154. Epub 2021 May 30.

U.O.C Cardiochirurgia Adulti, Ospedale del Cuore G. Pasquinucci, Fondazione Toscana Fabriele Monasterio, Massa, Italy.

Background: Early treatment of aortic valve stenosis is recommended in eligible symptomatic patients with severe aortic valve stenosis who would otherwise have a poor prognosis. The sutureless aortic valve bioprosthesis offers an alternative to standard aortic valve replacement with a sutured valve, but limited data are available in patients who have undergone multiple valve procedures involving the new, sutureless technology. We sought to investigate outcomes in high operative risk patients with previous or concomitant valve surgery who were implanted with a sutureless valve. Read More

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Does chest shape influence exercise stress echocardiographic results in patients with suspected coronary artery disease?

Intern Emerg Med 2021 May 30. Epub 2021 May 30.

Cardiology and Cardiovascular Pathophysiology, Azienda Ospedaliero-Universitaria "S. Maria Della Misericordia", Perugia, Italy.

Despite the good specificity of exercise stress echocardiography (ESE) for the detection of coronary artery disease (CAD), false positive (FP) results may occur. We have previously reported that chest abnormalities may affect parameters of cardiac contractility. The influence of chest shape on ESE results has never been previously investigated. Read More

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Coexistent Mitral Stenosis and left Circumflex Coronary Artery to left Atrial Fistula in a Patient with Severe Pulmonary Hypertension.

Braz J Cardiovasc Surg 2021 Apr 1;36(2):265-267. Epub 2021 Apr 1.

Yancheng Third People's Hospital, Yancheng, China.

Coronary artery to left atrial fistula is rare in patients with mitral stenosis. We report an interesting case of a patient with concomitant mitral valve stenosis and coronary fistulae, originating from the left circumflex artery and drained into the left atrium with two terminal orifices. Read More

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Prevalence and follow-up of subclinical rheumatic heart disease among asymptomatic school children in a north-western district of India based on the World Heart Federation echocardiographic criteria.

Echocardiography 2021 May 28. Epub 2021 May 28.

Cardiovascular Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.

Background: The present study is based on the World Heart Federation (WHF) echocardiographic criteria to assess the prevalence of subclinical rheumatic heart disease (RHD) and elucidate evolution of the disease when the cases were placed on appropriate antibiotic prophylaxis and regular follow-up. The prevalence of subclinical RHD reported by previous active surveillance studies among asymptomatic school children is not comparable to our study because of major differences in screening methods.

Methods: A random inclusion strategy was adopted to recruit urban and rural school children of Bikaner district in the state of Rajasthan, India. Read More

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Comprehensive echocardiographic prediction of postprocedural transmitral pressure gradient following transcatheter mitral valve repair.

Int J Cardiovasc Imaging 2021 May 27. Epub 2021 May 27.

Department of Cardiology and Intensive Care, Asklepios Klinik St. Georg, Lohmühlenstrasse 5, 20099, Hamburg, Germany.

Iatrogenic mitral stenosis following transcatheter mitral valve repair (TMVR) for relevant mitral regurgitation (MR) is a potential adverse side-effect, known to affect long-term outcome. However, only few determinants of an elevated mean transmitral pressure gradient (TMPG) have been described thus far. We sought to develop an integrative model for the prediction of TMPG following MitraClip (MC) therapy. Read More

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Survival of people with valvular heart disease in a large, English community-based cohort study.

Heart 2021 May 24. Epub 2021 May 24.

Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.

Objective: Valvular heart disease (VHD) is present in half the population aged >65 years but is usually mild and of uncertain importance. We investigated the association between VHD and its phenotypes with all-cause and cause-specific mortality.

Methods: The OxVALVE (Oxford Valvular Heart Disease) population cohort study screened 4009 participants aged >65 years to establish the presence and severity of VHD. Read More

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Adverse cardiovascular disease outcomes in patients with aortic sclerosis and mitral annular calcification even when valve function is normal.

Heart 2021 May 24. Epub 2021 May 24.

Cardiology, University of Poitiers, Clinical Investigation Center (CIC) INSERM 1402, Poitiers University Hospital, Poitiers, France.

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Double valve replacement in a patient with Maroteaux - Lamy syndrome as an ultimate team challenge.

J Cardiothorac Surg 2021 May 24;16(1):141. Epub 2021 May 24.

Cardiovascular Surgery Department, Athens Medical Center, Athens, Greece.

Background: The Maroteaux-Lamy syndrome (Mucopolysaccharidosis type VI) is a rare, inherited metabolic disease that results in progressive tissue accumulation of dermatan-sulfated glycosaminoglycans and inflammatory consequences that almost always affects the heart valves. From the anesthesia point of view, managing the airway and ventilation might be a serious challenge due to specific features of the syndrome. Additionally, it is more than probable that the surgical team will perform a non-straightforward procedure. Read More

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Impact of sex on the management and outcome of aortic stenosis patients.

Eur Heart J 2021 May 23. Epub 2021 May 23.

Institut Universitaire de Cardiologie et de Pneumologie de Québec (Quebec Heart & Lung Institute), 2725 Chemin Sainte-Foy, Quebec, QC G1V-4G5, Canada.

Objective: The aim of this study was to assess the impact of sex on the management and outcome of patients according to aortic stenosis (AS) severity.

Introduction: Sex differences in the management and outcome of AS are poorly understood.

Methods: Doppler echocardiography data of patients with at least mild-to-moderate AS [aortic valve area (AVA) ≤1. Read More

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Prognostic Implications of Associated Cardiac Abnormalities Detected on Echocardiography in Patients With Moderate Aortic Stenosis.

JACC Cardiovasc Imaging 2021 May 12. Epub 2021 May 12.

Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands. Electronic address:

Objectives: This study aimed to evaluate the prevalence and prognostic value of the extent of extra-aortic valvular cardiac abnormalities in a large multicenter registry of patients with moderate AS.

Background: The prognostic significance of a new classification system that incorporates the extent of cardiac injury (beyond the aortic valve) has been proposed in patients with severe aortic stenosis (AS). Whether this can be applied to patients with moderate AS is unclear. Read More

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Commentary: Functional Mitral Stenosis After Undersizing Mitral Annuloplasty for Ischemic Mitral Regurgitation: Ignoring the Elephant in the Room.

Semin Thorac Cardiovasc Surg 2021 May 15. Epub 2021 May 15.

Structural Heart Research and Innovation Laboratory, Carlyle Fraser Heart Center at Emory University Hospital Midtown, Atlanta, Georgia; Division of Cardiothoracic Surgery, Emory University, Atlanta, Georgia. Electronic address:

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L-wave in severe mitral stenosis.

Acta Cardiol 2021 May 17:1-2. Epub 2021 May 17.

Department of Cardiology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.

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Fetal growth of left-sided structures and postnatal surgical outcomes in the "borderline" left heart varies by cardiac phenotype.

Ultrasound Obstet Gynecol 2021 May 16. Epub 2021 May 16.

Texas Children's Hospital, Department of Pediatrics.

Objectives: Two "borderline" left heart phenotypes are evident in the fetus: 1) severe aortic stenosis (AS), which is associated with a globular left ventricle (LV), systolic LV dysfunction, and LV growth arrest, and 2) left heart hypoplasia (LHH) which is associated with a "long, skinny" LV, laminar flow across hypoplastic mitral and aortic valves, and arch hypoplasia. Both phenotypes may be counseled for possible single ventricle palliation. We aimed to compare the rates left sided structure growth and Z-score change over gestation by phenotype. Read More

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Remarkable oxygen consumption improvement after auricular flutter ablation in a patient with constrictive pericarditis and severe mitral stenosis.

J Cardiol Cases 2021 May 26;23(5):227-230. Epub 2020 Nov 26.

Cardiac Arrhythmia and Electrophysiology Unit, Department of Cardiology, Hospital Clínico Universitario San Cecilio, Granada, Spain.

Atrial function is a key factor in cardiac output and oxygen consumption (VO). Substantial improvements in VO have been reported after restoring sinus rhythm (SR) in patients with atrial fibrillation. However, there are no published data on how atrial function affects VO in patients with both constrictive pericarditis (CP) and severe mitral stenosis (MS). Read More

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Effect of Transcatheter Aortic Valve Replacement on Concomitant Mitral Regurgitation and Its Impact on Mortality.

JACC Cardiovasc Interv 2021 Jun 12;14(11):1181-1192. Epub 2021 May 12.

Servicio de Cardiología, Hospital Álvaro Cunqueiro, Vigo, Spain.

Objectives: The purpose of this study was to examine the impact of residual mitral regurgitation (MR) on mortality in patients undergoing transcatheter aortic valve replacement (TAVR).

Background: MR is common in patients undergoing TAVR. Data on optimal management of patients with significant MR after TAVR are limited. Read More

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