78,642 results match your criteria Mitral Regurgitation


Impact of Hybrid Therapy Comprising Peritoneal Dialysis and Hemodialysis on Acute Cardiovascular Events.

Blood Purif 2018 Dec 6:1-7. Epub 2018 Dec 6.

Background: The impact of hybrid therapy comprising peritoneal dialysis (PD) and hemodialysis on cardiovascular events in PD patients remains unclear.

Objective: We aimed to evaluate the effect of hybrid therapy on cardiovascular events.

Methods: A total of 93 PD patients undergoing hybrid therapy for ≥3 years were divided into 2 groups according to left ventricular ejection fraction (LVEF): lower ejection fraction (LEF [n = 29], LVEF < 60%) and normal ejection fraction (NEF [n = 64], LVEF ≥60%). Read More

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December 2018
2 Reads

Intraventricular blood flow with a fully dynamic mitral valve model.

Comput Biol Med 2018 Nov 29;104:197-204. Epub 2018 Nov 29.

Department of Chemical Engineering, Faculty of Applied Science, Delft University of Technology, the Netherlands.

Mitral valve (MV) leaflets affect the formation, growth, and decay of vortices in the left ventricle (LV) during diastolic filling. The shape and motion of MV leaflets are simplified in most studies due to computational restrictions. In this study, we present a newly developed mathematical method to model the dynamic movement of valve leaflets and annulus, which is based on in vivo data obtained with magnetic resonance imaging (MRI). Read More

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November 2018
2 Reads

Risk factors for recoarctation of aorta after Norwood procedure in patients with hypoplastic left heart syndrome.

Folia Med Cracov 2018 ;58(3):11-21

Department of Pediatric Cardiac Surgery, University Children's Hospital, Jagiellonian University Medical College, Wielicka 265, Kraków, Poland.

Background: Recoarctation (reCoA) of the aorta is a common complication afer the Norwood procedure. Untreated, it can lead to failure of the systemic ventricle and death. The main goal of the study is to define risk factors of reCoA after the Norwood procedure in hypoplastic left heart syndrome (HLHS). Read More

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January 2018

Emergent surgical treatment of lethal valve dysfunction during pregnancy in a last-trimester patient.

Saudi Med J 2018 Dec;39(12):1249-1252

Department of Cardiovascular Surgery, Selcuk University, Konya, Turkey. E-mail.

A mechanical heart valve thrombosis during pregnancy is one of the most lethal conditions to experience due to its detrimental effects on both mother and fetus. Cardiac surgery during pregnancy is reserved for cases where medical treatment fails due to harmful maternal and fetal effects. A 24-year-old female in the 38th week of pregnancy was admitted to the emergency room with aggravated dyspnea, tachypnea, and palpitations. Read More

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December 2018

Retrospective analysis of 11 cases of primary cardiac valve tumors.

Anatol J Cardiol 2018 Dec 6. Epub 2018 Dec 6.

Department of Ultrasound Diagnosis, The Second Affiliated Hospital (Xinqiao Hospital) of Chinese People's Liberation Army Medical University; Chongqing-China.

Objective: To explore the clinical features and surgical treatment experience of primary cardiac valve tumor.

Methods: The present study retrospectively analyzed the clinical data of 11 patients with primary valvular tumors who underwent surgical treatment in our department from 1980 to 2016. Echocardiography of preoperative patients was indicated as a heart valve tumor. Read More

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December 2018

Impact of left atrial box surface ratio on the recurrence after ablation for persistent atrial fibrillation.

Pacing Clin Electrophysiol 2018 Dec 5. Epub 2018 Dec 5.

Department of Cardiology, Leiden University Medical Center, University of Leiden, Leiden, The Netherlands.

Background: The posterior wall of the left atrium (LA) is a well-known substrate for atrial fibrillation (AF) maintenance. Isolation of the posterior wall between the pulmonary veins (box lesion) may improve ablation success. Box lesion surface area size varies depending on the individual anatomy. Read More

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December 2018

Hypertrophic obstructive cardiomyopathy and mitral regurgitation in Libman-Sacks endocarditis.

Gen Thorac Cardiovasc Surg 2018 Dec 5. Epub 2018 Dec 5.

Department of Cardiovascular Surgery, Mitsubishi Kyoto Hospital, 1 Goshomachi, Nishikyo-ku, Kyoto, 615-8087, Japan.

Hypertrophic obstructive cardiomyopathy in Libman-Sacks endocarditis is quite rare and the correct etiological relationship between them is unknown. Some changes may cause a secondary disorganization of the ordinary muscle structure, making a disarray pattern with irregular interwoven myocyte fibers. This case report describes one of the first cases of ventricular septal myectomy and mitral valve replacement for hypertrophic obstructive cardiomyopathy and mitral valve regurgitation associated with Libman-Sacks endocarditis. Read More

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December 2018

Involvement of Apelin/APJ Axis in Thrombogenesis in Valve Heart Disease Patients with Atrial Fibrillation.

Int Heart J 2018 Dec 5. Epub 2018 Dec 5.

Department of Cardiology, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University.

The mechanism underlying thrombosis in atrial fibrillation (AF) is not yet clearly understood. The apelin/APJ axis parallel and counter-regulate with the angiotensin system. The present study hypothesizes that apelin/APJ axis exert its anti-thrombus effect in normal left atrial tissue and is disrupted by up-regulated renin-angiotensin-aldosterone system (RAAS) signaling during AF. Read More

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December 2018

Characteristics, Mechanism and Long-Term Ablation Outcome of Atrial Tachycardias After Mitral Valvular Surgery and Concomitant Cox-MAZE IV Procedure.

Int Heart J 2018 Dec 5. Epub 2018 Dec 5.

Department of Cardiology, Atrial Fibrillation Center, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences.

The incidence of atrial tachycardia (AT) after rheumatic mitral valvular (RMV) surgery has been well described. However, there have been few reports on the characteristics, mechanism, and long-term ablation outcome of ATs after RMV surgery and concomitant Cox-MAZE IV procedure.The present study reviewed consecutive patients who underwent AT ablation between May 2008 and July 2013. Read More

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December 2018

[Heart Valve Disease - update ESC guideline 2017].

Dtsch Med Wochenschr 2018 Dec 3;143(24):1765-1769. Epub 2018 Dec 3.

Klinik für Kardiologie, Pneumologie und Angiologie, Universitätsklinikum Düsseldorf, Düsseldorf.

Surgical management of patients with aortic valve stenosis is declining and Transcatheter aortic valve implantation (TAVI) is becoming the treatment of choice in many patients. The ESC guideline integrated results of randomized controlled trials in patients with intermediate surgical risk for the first time. TAVI showed good and comparable results to the standard surgical approach. Read More

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December 2018
1 Read

Myocardial fibrosis predicts adverse outcome after MitraClip implantation.

Catheter Cardiovasc Interv 2018 Dec 3. Epub 2018 Dec 3.

Department of Cardiology, Amsterdam Cardiovascular Sciences, Amsterdam UMC, Heart Center, University of Amsterdam, Amsterdam, The Netherlands.

Background: High-risk patients with mitral regurgitation (MR) may be treated by a percutaneous mitral valve repair with the MitraClip, but identification of patients who may benefit remains difficult. We aimed to determine whether myocardial fibrosis predicts outcome in MR patients undergoing MitraClip implantation and is beneficial in clinical decision making.

Methods: Preprocedural to the MitraClip implantation, myocardial fibrosis was analyzed with cardiovascular magnetic resonance (CMR) through late gadolinium enhancement. Read More

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December 2018

Natural history of bivalvular functional regurgitation.

Eur Heart J Cardiovasc Imaging 2018 Dec 1. Epub 2018 Dec 1.

Department of Internal Medicine II, Medical University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria.

Aims: Bivalvular functional regurgitation (BVFR) defined as concomitant mitral and tricuspid insufficiency has not been described or systematically assessed before. Therefore, this study sought to define incidence, impact and natural history of BVFR in heart failure with reduced ejection fraction (HFrEF) to provide the foundation for risk assessment and directions for potential treatment strategies.

Methods And Results: We enrolled 1021 consecutive patients with HFrEF under guideline-directed medical therapy and performed comprehensive echocardiographic and neurohumoral profiling. Read More

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December 2018

Mitral valve replacement with a pulmonary autograft: long-term follow-up in an infant.

Interact Cardiovasc Thorac Surg 2018 Dec 1. Epub 2018 Dec 1.

M3C National Reference Center, Department of Pediatric Cardiology, Hôpital Necker-Enfants Malades, APHP, Université Paris Descartes, Paris, France.

A 7-month-old boy with a complete atrioventricular septal defect presented with severe left atrioventricular valve regurgitation 4 months after complete repair. As the valve was unsuitable for the repair and the annulus was too small to accommodate a mechanical prosthesis, the modified mitral Ross operation was performed. The long-term outcome was uneventful for 12 years. Read More

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December 2018

Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat.

J Vis Exp 2018 Nov 18(141). Epub 2018 Nov 18.

Department of Medicine, Queen's University; Department of Pediatrics, The Jikei University School of Medicine;

The mechanism of mitral stenosis-induced pulmonary venous arterialization and group 2 pulmonary hypertension (PH) is unclear. There is no rodent model of group 2 PH, due to mitral stenosis (MS), to facilitate the investigation of disease mechanisms and potential therapeutic strategies. We present a novel rat model of pulmonary venous congestion-induced pulmonary venous arterialization and group 2 PH caused by left atrial stenosis (LAS). Read More

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November 2018

Electrocardiographic and echocardiographic features in patients with major arterial vascular disease assigned to surgical revascularization.

Acta Cardiol 2018 Dec 3:1-7. Epub 2018 Dec 3.

a Dipartimento di Medicina Interna e Scienze Biomediche, Sezione di Cardiologia , Università degli Studi di Parma , Parma , Italy.

Background: We aimed to depict the electrocardiographic and echocardiographic aspects in patients before elective major vascular surgery.

Methods: We evaluated through standard 12 lead electrocardiography and transthoracic echocardiography 469 patients with asymptomatic large abdominal aortic aneurysm (AAA), 334 with critical carotid stenosis (CAS), and 238 with advanced peripheral artery disease (PAD) before surgical revascularization.

Results: Patients with AAA were predominantly males (p < . Read More

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December 2018

In-hospital outcomes of transcatheter mitral valve repair with Mitraclip in patients with pulmonary hypertension: Insights from the National Inpatient Sample.

Catheter Cardiovasc Interv 2018 Dec 2. Epub 2018 Dec 2.

Department of Cardiovascular Medicine, Wayne State University/Detroit Medical Center, Detroit, Michigan.

Background: Periprocedural outcomes of transcatheter mitral valve repair (TMVR) with Mitraclip in patients with pulmonary hypertension (PH) are not well studied.

Methods: Patients who underwent TMVR with Mitraclip between 2011 and 2015 were identified using the National Inpatient Sample (NIS). All missing variables were excluded from the analysis and therefore, complete case analysis was performed. Read More

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December 2018

Mitral valve velocity time integral and passive leg raise as a measure of volume responsiveness.

Crit Ultrasound J 2018 Dec 2;10(1):32. Epub 2018 Dec 2.

Department of Emergency Medicine, Ben Taub Hospital, Baylor College of Medicine, 1400 Taub Loop, Houston, TX, USA.

Background: Fluid responsiveness is an important topic for clinicians. Aggressive hydration has been shown to lead to worse outcomes. The aim of this study was to investigate the sensitivity and specificity of mitral valve (MV) velocity time integral (VTI) as a non-invasive marker of volume responsiveness. Read More

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December 2018

Simultaneously surgical management of adult complex coarctation of aorta concomitant with intracardiac abnormality.

J Thorac Dis 2018 Oct;10(10):5842-5849

Department of Cardiovascular Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.

Background: To explore surgical management of complex coarctation of aorta (COA) concomitant with intracardiac abnormality, in order to provide recommendations for safe and reliable treatment.

Methods: Totally, six adult cases demonstrating complex COA concomitant with intracardiac abnormality were reviewed from our department between May 2012 and June 2017. Four patients were male and two patients were female, the age range being 43. Read More

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October 2018

Rheumatic Mitral Stenosis with Incidental Wolff-Parkinson-White Syndrome: A Rare Association. Treated by Percutaneous Transmitral Commissurotomy and Radiofrequency Ablation.

Heart Views 2018 Apr-Jun;19(2):58-62

Department of Cardiology, Heart Hospital, Hamad Medical Corporation, Doha, Qatar.

The combination of Wolff-Parkinson-White (WPW) syndrome and rheumatic mitral stenosis (MS) is rare in clinical practice. The management of this condition primarily depends on the clinical picture. We describe a 26-year-old male patient with no significant previous medical history and who came for a routine medical assessment before entrance to a police academy service. Read More

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December 2018

Concomitant left main coronary artery and prosthetic mitral valve thrombosis treatment.

Authors:
Ayhan Olcay

Anatol J Cardiol 2018 Dec;20(6):365-367

Department of Cardiology, Faculty of Medicine, İstanbul Aydın University; İstanbul-Turkey.

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December 2018

Surgical treatment of right-sided infective endocarditis.

J Thorac Cardiovasc Surg 2018 Sep 25. Epub 2018 Sep 25.

Heart and Vascular Institute, Department of Thoracic and Cardiovascular Surgery. Electronic address:

Objective: Right-sided infective endocarditis is increasing because of increasing prevalence of predisposing conditions, and the role and outcomes of surgery are unclear. We therefore investigated the surgical outcomes for right-sided infective endocarditis.

Methods: From January 2002 to January 2015, 134 adults underwent surgery for right-sided infective endocarditis. Read More

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September 2018

Transcatheter aortic valve replacement in patients with degenerative calcified rheumatic aortic stenosis: A 10-patient case series.

Int J Cardiol 2018 Nov 16. Epub 2018 Nov 16.

Department of Cardiology, Sakakibara Heart Institute, Tokyo, Japan.

Background: Transcatheter aortic valve replacement (TAVR) for patients with rheumatic heart disease (RHD) has not been well-known. This study aimed to assess characteristics and computed tomography (CT) findings of the aortic valve in old patients with RHD and to investigate the safety and efficacy in the patients who underwent TAVR.

Methods And Results: Of 352 consecutive patients with severe aortic stenosis (AS) who underwent TAVR at the Sakakibara Heart Institute between 2013 and 2016, 10 patients (2. Read More

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November 2018

Transcatheter treatment of functional mitral regurgitation after MITRA-FR and COAPT - Patient selection is most important.

Int J Cardiol 2018 Nov 24. Epub 2018 Nov 24.

Medizinische Klinik und Poliklinik I, Ludwig-Maximilians-Universität München, Munich, Germany.

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November 2018

Hematopoietic cell transplantation for severe MPS I in the first six months of life: The heart of the matter.

Mol Genet Metab 2018 Nov 13. Epub 2018 Nov 13.

Division of Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota Medical School, Minneapolis, MN, United States.

Background: Hematopoietic cell transplantation (HCT) is accepted therapy for severe mucopolysaccharidosis type I (MPS IH). With implementation of newborn screening (NBS) for MPS I in the US, HCT may now occur earlier than 1-2 years of age and it might be assumed that cardiac issues will be fewer. To examine this hypothesis, we reviewed our records for any MPS IH infant who underwent HCT at ≤6 months of age. Read More

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November 2018

MitraClip implantation in younger patients and pediatric populations: 19 year-old patient with multiple comorbidities and a prior mitral valve annuloplasty.

Cardiovasc Revasc Med 2018 Nov 23. Epub 2018 Nov 23.

Bahcesehir University School of Medicine, Istanbul, Turkey; Arkansas Heart Hospital, 72211, AR, United States of America. Electronic address:

MitraClip is an effective treatment method for severe mitral regurgitation in high-risk populations in terms of reducing morbidity and frequency of hospitalizations. Efficacy and safety of MitraClip device in elderly population have been established, yet there are only 2 case reports of MitraClip implantation in the younger patients, who generally tend to have less surgical risk (Gorenflo et al.; Joffe et al. Read More

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November 2018

Use of oral anticoagulants in complex clinical situations with atrial fibrillation.

Med Clin (Barc) 2018 Jun;150 Suppl 1:8-24

Servicio de Medicina Interna, Hospital Universitario de La Princesa, Madrid, España. Electronic address:

The present article provides an update on anticoagulant treatment in patients with atrial fibrillation in distinct clinical scenarios requiring particular considerations, such as ischaemic heart disease, electrical cardioversion, pulmonary vein ablation, the presence of valvular disease with or without prosthetic valves, and renal insufficiency, as well as old age and frailty. In patients with non-valvular atrial fibrillation, the presence of renal insufficiency increases both thrombotic and haemorrhagic risk. In mild and moderate stages, direct-acting anticoagulants confer a greater benefit than warfarin, although they usually require dose adjustment. Read More

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Relation of Hepatic Fibrosis in Nonalcoholic Fatty Liver Disease to Left Ventricular Diastolic Function and Exercise Tolerance.

Am J Cardiol 2018 Nov 6. Epub 2018 Nov 6.

Division of Gastroenterology - Hepatology Division, Virginia Commonwealth University, Richmond, Virginia.

The purpose of this study was to determine the relation between liver histology, exercise tolerance, and diastolic function in patients with nonalcoholic fatty liver disease (NAFLD). Myocardial remodeling and diastolic dysfunction have been associated with NAFLD. However, its physiological impact and relationship to the histological severity of NAFLD is not known. Read More

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November 2018

Edwards Inspiris Resilia® valve for mitral replacement in an infant after mechanical valve failure.

Cardiol Young 2018 Dec 3:1-3. Epub 2018 Dec 3.

1Department for Pediatric Cardiothoracic Surgery,Children's Memorial Health Institute,Warsaw,Poland.

We present the surgical implantation of the Edwards Inspiris Resilia® aortic valve in mitral position for mechanical mitral valve failure in a severely ill infant after valve replacement because of anomalous origin of the left coronary artery from the pulmonary artery. The biological valve was chosen because the child could not receive oral anticoagulation and was for several months on heparin infusion. The procedure was safely performed with good haemodynamic result. Read More

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December 2018

Evaluation of sepsis induced cardiac dysfunction as a predictor of mortality.

Cardiovasc Ultrasound 2018 Nov 30;16(1):31. Epub 2018 Nov 30.

MICU, St John's Medical College, Kormangala, Bangalore, 560034, India.

Background: Sepsis is characterized by life threatening organ dysfunction with dysregulated immune response. Cardiac dysfunction seen in sepsis is unique as it is reversible within 7-10 days. Initial study by Parker et al. Read More

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November 2018

A diver with immersion pulmonary oedema and prolonged respiratory symptoms.

Diving Hyperb Med 2018 Dec;48(4):259-261

Department of Pulmonary Medicine, Kameda Medical Centre, Kamogawa, Chiba, Japan.

Immersion pulmonary oedema (IPE) is particularly associated with an excessive reaction to exercise and/or cold stress. IPE usually resolves without recompression therapy within a day or two. Herein we report a diver diagnosed with IPE, in whom symptoms persisted for five days. Read More

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December 2018
1 Read

The unique mechanism of functional mitral regurgitation in acute myocardial infarction: a prospective dynamic 4D quantitative echocardiographic study.

Eur Heart J Cardiovasc Imaging 2018 Dec 4. Epub 2018 Dec 4.

Department of Cardiovascular Diseases, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

Aims: Mechanisms of chronic ischaemic mitral regurgitation (IMR) are well-characterized by apically tethered leaflet caused by papillary muscles (PMs) displacement and adynamic mitral apparatus. We investigated the unique geometry and dynamics of the mitral apparatus in first acute myocardial infarction (MI) by using quantified 3D echocardiography.

Methods And Results: We prospectively performed 3D echocardiography 2. Read More

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December 2018
1 Read

Q-PULS, a new quasi-physiological pulsatile extracorporeal model to simulate heart function.

Interact Cardiovasc Thorac Surg 2018 Dec 4. Epub 2018 Dec 4.

Department of Cardiovascular Surgery, Heart Center Brandenburg, University Hospital, Brandenburg Medical School, Bernau bei Berlin, Germany.

Objectives: The invention of new surgical procedures requires testing at different stages including animal models. To facilitate this process, we have developed a computer-controlled extracorporeal circulation system for testing of an explanted porcine heart simulating a variety of physiological parameters. Mitral valve function can be assessed before and after induced valve insufficiency and after valve repair. Read More

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December 2018

Mid-term results of a randomized trial of tricuspid annuloplasty for less-than-severe functional tricuspid regurgitation at the time of mitral valve surgery†.

Eur J Cardiothorac Surg 2018 Dec 4. Epub 2018 Dec 4.

Cardiac Surgery Department, Universitair Clinique St. Luc, Brussel, Belgium.

Objectives: The optimal management of functional tricuspid regurgitation (FTR) in the setting of mitral valve operations remains controversial. The current practice is both centre specific and surgeon specific with guidelines based on non-randomized data. A prospective randomized trial was performed to evaluate the worth of less-than-severe FTR repair during mitral valve procedures. Read More

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December 2018
1 Read

Male-female differences in characteristics and early outcomes of patients undergoing tricuspid valve surgery: a national cohort study in the Netherlands.

Eur J Cardiothorac Surg 2018 Dec 4. Epub 2018 Dec 4.

Department of Cardiothoracic Surgery, Erasmus MC, Rotterdam, Netherlands.

Objectives: This study aims to explore male-female differences in baseline and procedural characteristics, and outcomes of patients undergoing isolated or concomitant tricuspid valve (TV) surgery.

Methods: All TV procedures registered between 2007 and 2016 in the database of the Netherlands Association for Cardio-Thoracic Surgery were analysed. Logistic regression analyses with interaction terms were used to determine whether sex was associated with hospital mortality. Read More

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December 2018

Comparison of del Nido Cardioplegia with Blood Cardioplegia in Coronary Artery Bypass Grafting Combined with Mitral Valve Replacement.

Braz J Cardiovasc Surg 2018 Sep-Oct;33(5):496-504

Department of Cardiovascular Surgery, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey.

Objective: To compare del Nido cardioplegia (DNC) with blood cardioplegia (BC) in coronary artery bypass grafting (CABG) combined with mitral valve replacement.

Methods: A 3-year single-center retrospective cohort study was carried out. Subjects who underwent CABG (up to triple bypass) combined with mitral valve replacement were divided into DNC and BC groups. Read More

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Contemporary Surgical Techniques for Mitral Valve Repair: A Pathoanatomic Appraisal.

Semin Cardiothorac Vasc Anesth 2018 Dec 5:1089253218815465. Epub 2018 Dec 5.

1 Department of Cardiovascular and Thoracic Surgery, West Virginia University, Morgantown, WV, USA.

Mitral valve surgery has evolved over 4 decades from one based on the principles of prosthetic replacement to a subspecialty with a foundation based on the principles of repair. This review will attempt to enumerate the contemporary techniques of mitral valve repair and a pathoanatomically directed approach with which to apply them by focusing on degenerative disease and associated complexities. Read More

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December 2018
1 Read

Left Ventricular Strain and Relaxation Are Independently Associated with Renal Cortical Perfusion in Hypertensive Patients.

Adv Exp Med Biol 2018 Dec 4. Epub 2018 Dec 4.

Department of Internal Diseases, Nephrology and Dialysis, Military Institute of Medicine, Warsaw, Poland.

Renal perfusion, which depends on cardiac function, is a factor conditioning the work of kidneys. The objective of the study was to assess the influence of cardiac function, including left ventricular contractility and relaxation, on renal cortical perfusion in patients with hypertension and chronic kidney disease treated pharmacologically. There were 63 patients (7 F and 56 M; aged 56 ± 14) with hypertension and stable chronic kidney disease enrolled into the study. Read More

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December 2018

The Multivalvular Score for Predicting the Outcome of Mitral Regurgitation in Aortic Stenosis Patients Treated With TAVI: Prospective Validation.

Rev Esp Cardiol (Engl Ed) 2018 Dec 1. Epub 2018 Dec 1.

Instituto de Ciencias del Corazón (ICICOR), Hospital Clínico Universitario de Valladolid, Valladolid, Spain; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Hospital Clínico Universitario de Valladolid, Valladolid, Spain.

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December 2018

Valvulopathies médicamenteuses.

Rev Prat 2016 Oct;66(8):874-880

Département de cardiologie, hôpital de la Cavale Blanche, CHRU de Brest, Brest, France.

Drug-induced valve heart disease. Numerous reports have shown an unquestionable association between fibrotic valve heart disease (VHD) and the following drugs: ergot alkaloids (methysergide and ergotamine), ergot-derived dopaminergic agonists (pergolide and cabergoline) and drugs metabolized into norfenfluramine (fenfluramine, dexfenfluramine and benfluorex). These drugs have a common pharmacological action on a specific serotonin receptor - the 5HT2B receptor leading to VHD. Read More

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October 2016
1 Read

Trifecta Aortic Bioprosthesis: Midterm Results in 1,953 Patients from a Single Center.

Ann Thorac Surg 2018 Dec 1. Epub 2018 Dec 1.

Division of Cardiac Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA; Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, PA.

Background: The St. Jude Medical Trifecta bioprosthesis is a bovine pericardial valve mounted on a titanium stent. The objective of this study was to report a single center experience with the Trifecta aortic valve. Read More

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December 2018
1 Read

Reinventing the saphenous vein: Reconstructing the anterior mitral leaflet with a saphenous vein.

Ann Thorac Surg 2018 Dec 1. Epub 2018 Dec 1.

Division of Cardiology, Stellenbosch University , Tygerberg, South Africa.

Mitral valve repair can sometimes require leaflet augmentation or a patch repair of a defect in the leaflet. No ideal patch material is currently available which can grow and adapt with the mitral leaflet. We describe a new technique by using autologous saphenous vein as patch material. Read More

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December 2018
1 Read

A pilot study investigating circulating trimethylamine N-oxide and its precursors in dogs with degenerative mitral valve disease with or without congestive heart failure.

J Vet Intern Med 2018 Dec 3. Epub 2018 Dec 3.

Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, North Grafton, Massachusetts.

Background: Pathophysiologic mechanisms for the development and progression of degenerative mitral valve disease (DMVD) remain elusive. Increased concentrations of circulating trimethylamine N-oxide (TMAO) and its precursors choline and l-carnitine are associated with the presence and severity of heart disease in people.

Objectives: To determine if differences exist in plasma concentrations of TMAO, choline, or l-carnitine among dogs with DMVD and congestive heart failure (CHF), dogs with asymptomatic DMVD, and healthy control dogs. Read More

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December 2018
3 Reads

Double-orifice mitral valve repair.

Cardiol Young 2018 Dec 4:1-2. Epub 2018 Dec 4.

Division of Congenital Cardiac Surgery,Malaga General Hospital,Malaga,Spain.

We present the case of a 6-year-old patient with double-orifice mitral valve and severe regurgitation, which was successfully repaired. We demonstrate that mitral valve repair may be attempted even in complex anatomy such as the double-orifice mitral valve, where it can offer excellent results. Read More

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December 2018

Further percutaneous dilation of a Melody® valve in the mitral position to accommodate somatic growth in a small child: lessons learned.

Cardiol Young 2018 Dec 4:1-3. Epub 2018 Dec 4.

3Division of Pediatric Cardiology,UC Davis Children's Hospital,Sacramento, CA,USA.

A 15-month-old child underwent percutaneous expansion of a Melody transcatheter pulmonary valve in the mitral position to accommodate growth after initial surgical implantation during infancy, but transiently decompensated after valvuloplasty owing to stent malformation. The Melody valve in the mitral position of small patients can be further expanded by percutaneous dilation, but there are a number of potential complications and technical improvements to consider. Read More

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December 2018
1 Read

Insights into functional mitral regurgitation using the average pixel intensity method.

Int J Cardiovasc Imaging 2018 Dec 3. Epub 2018 Dec 3.

Department of Cardiology, Heart Center, Ghent University Hospital, Cornelis Heymanslaan 10, 10-K12, 9000, Ghent, Belgium.

Previously we introduced and validated the average pixel intensity (API) method for grading mitral regurgitation (MR) in a heterogeneous MR population. We now investigated the feasibility and added value of the API method more specifically in patients with functional MR (FMR). We consecutively enrolled 283 patients with pure FMR. Read More

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December 2018
5 Reads

Is overreduction of the mitral annulus for valve competence considered mitral valve repair? Addressing prosthesis-patient mismatch.

J Cardiol 2019 Feb 28;73(2):183-184. Epub 2018 Jun 28.

Department of Thoracic and Cardiovascular Surgery, Wonkwang University School of Medicine, Iksan, Chonbuk, South Korea.

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February 2019

Infective endocarditis complicated with nonobstructive ST elevation myocardial infarction related to septic embolism with intracranial hemorrhage: A case report.

Medicine (Baltimore) 2018 Nov;97(48):e13089

Division of Cardiology, Department of Internal Medicine, Kaohsiung Medical University Hospital.

Rationale: Infective endocarditis (IE) complicated with obstructive ST elevation myocardial infarction (STEMI) has been reported in the literature and which were mostly related to coronary artery embolism, obstruction, or compression. However, there has been no reported case discussing about IE complicated with nonobstructive STEMI.

Patient Concerns: In this report, we report a 38-year-old female suffering from intermittent fever and was later diagnosed as IE. Read More

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November 2018
1 Read

Alternative strategies to improve success rate of mitral isthmus block.

Medicine (Baltimore) 2018 Nov;97(48):e13060

Heart Institute, Asan Medical Center, University of Ulsan College of Medicine, Seoul.

Achieving bidirectional conduction block (BDB) across the mitral isthmus (MI) is technically challenging. We describe our experience using different ablation strategies for achieving successful MI block.We reviewed the records of patients who had undergone MI ablation for peri-mitral (PM) flutter at our institution from January 2010 to May 2015. Read More

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November 2018
2 Reads

Difference in Outcome Following Surgery for Native Aortic and Mitral Valve Infective Endocarditis.

Thorac Cardiovasc Surg 2018 Nov 30. Epub 2018 Nov 30.

Department of Cardiothoracic Surgery, Skane University Hospital and Lund University, Lund, Sweden.

Background:  We investigated differences in clinical presentation, microbiology, and short- and long-term results according to the affected valve in patients who underwent surgery for left-sided native valve infective endocarditis (IE).

Methods:  This was a single-center retrospective study of 117 patients with isolated mitral valve IE (group M) and 140 patients with isolated aortic valve IE (group A) who underwent surgery between 1998 and 2015.

Results:  The mean age of patients in group M was 62 ± 14 years, whereas in group A the patients were 56 ± 14 years old ( = 0. Read More

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November 2018
7 Reads

Response: Acute haemolysis after transcatheter mitral valve implantation.

Eur Heart J 2018 Nov 29. Epub 2018 Nov 29.

Department of Cardiology, Bichat Hospital, 46 rue Henri Huchard, Paris 75018, France.

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November 2018