35,037 results match your criteria Mitral Regurgitation


Left Thoracotomy Beating Heart Repair of Mitral Periprosthetic Regurgitation.

Ann Thorac Surg 2021 May 4. Epub 2021 May 4.

Division of Pediatric Cardiovascular Surgery, Masonic Children's Hospital Department of Surgery, University of Minnesota, Minneapolis, MN 55454. Electronic address:

Left thoracotomy is a recognized, albeit not a commonly utilized approach for mitral valve exposure. This approach represents a good alternative to repeat median sternotomy and repeat right thoracotomy especially in cases of hostile mediastinum. We present a 72-year-old woman who underwent a beating heart left thoracotomy repair of recurrent severe mitral periprosthetic regurgitation in the presence of a porcelain aorta. Read More

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Mitral regurgitation caused by perforation of a pseudoaneurysm of the mitral-aortic intervalvular fibrosa.

Eur Heart J Case Rep 2021 Apr 30;5(4):ytab163. Epub 2021 Apr 30.

Department of Cardiology, Hospital Universitario de Canarias, Ofra s/n, La Cuesta, La Laguna, Tenerife 38320, Spain.

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The Mitral INsufficiency Echocardiographic score: A severity classification of myxomatous mitral valve disease in dogs.

J Vet Intern Med 2021 May 5. Epub 2021 May 5.

Department of Cardiology, Anicura Istituto Veterinario Novara, Granozzo con Monticello, Italy.

Background: There is no commonly shared severity score for myxomatous mitral valve disease (MMVD) based on routinely acquired echocardiographic variables.

Hypothesis/objectives: To propose an easy-to-use echocardiographic classification of severity of MMVD in dogs.

Animals: Five hundred and sixty dogs with MMVD. Read More

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Rheumatic mitral regurgitation: is repair justified by the long-term results?

Interact Cardiovasc Thorac Surg 2021 May 5. Epub 2021 May 5.

Department of Cardiac Surgery, IRCCS San Raffaele Hospital, Vita-Salute San Raffaele University, Milan, Italy.

Objectives: The best treatment for rheumatic mitral regurgitation is still under debate. Our goal was to assess the long-term results of mitral repair for rheumatic mitral regurgitation performed in 2 referral centres for mitral repair.

Methods: Patients who underwent mitral valve repair between 1999 and 2009 were selected. Read More

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Preoperative risk factors influencing inter-stage mortality after the Norwood procedure.

Interact Cardiovasc Thorac Surg 2021 May 5. Epub 2021 May 5.

Department of Congenital and Pediatric Heart Surgery, German Heart Center Munich, Technische Universität München, Munich, Germany.

Objectives: With improvements in early survival after the stage I palliation (S1P) Norwood procedure for hypoplastic left heart syndrome (HLHS) and its variants, inter-stage death accounts for an increasing proportion of mortality. Our aim was to identify the risk factors for inter-stage mortality.

Methods: The records of 322 neonates with HLHS or a variant who underwent the Norwood procedure at our centre between 2001 and 2019 were retrospectively analysed. Read More

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Single-stage open repair of severe asymmetric pectus excavatum and mitral valve replacement in connective tissue disease.

Asian Cardiovasc Thorac Ann 2021 May 4:2184923211014004. Epub 2021 May 4.

Department of Surgery, Universiti Malaya, Kuala Lumpur, Malaysia.

We present a 14-year-old boy with Loey-Dietz syndrome with severe mitral regurgitation, pectus excavatum and scoliosis. The Haller index was 25. The heart was displaced into the left hemithorax. Read More

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Phenylephrine Provocation to Evaluate the Cause of Mitral Regurgitation in Patients With Obstructive Hypertrophic Cardiomyopathy.

Circ Cardiovasc Imaging 2021 May 4:CIRCIMAGING121012656. Epub 2021 May 4.

Division of Cardiology, Department of Medicine, Washington University, St Louis, MO. (J.D.M., R.G.B., S.C.M., S.C.).

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Mitral Surgery after Transcatheter Edge-to-Edge Repair: Society of Thoracic Surgeons Database Analysis.

J Am Coll Cardiol 2021 Apr 27. Epub 2021 Apr 27.

Department of Cardiovascular Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Background: Transcatheter edge-to-edge (TEER) mitral repair may be complicated by residual or recurrent mitral regurgitation. Increasing need for surgical reintervention has been reported but operative outcomes are ill-defined.

Objectives: This study evaluated national outcomes of mitral surgery after TEER. Read More

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Double leaflet technique for mitral regurgitation with the small or tethered posterior leaflet.

Ann Thorac Surg 2021 May 1. Epub 2021 May 1.

Department of Cardiovascular Surgery, Toranomon Hospital.

Small leaflets make mitral valve repair procedures challenging. Our double leaflet technique creates a new autologous pericardial leaflet attached to the papillary muscle, annuloplasty ring and neighboring scallops above the small or tethered posterior leaflet. This simple additional technique provides deep coaptation after mitral valve repair for both degenerative and functional mitral regurgitation with the small or tethered posterior leaflet. Read More

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Mitral prolapsing volume is associated with increased cardiac dimensions in patients with mitral annular disjunction.

Neth Heart J 2021 May 4. Epub 2021 May 4.

Department of Cardiology, Maastricht University Medical Centre, Maastricht, The Netherlands.

Introduction: In patients with mitral annular disjunction (MAD), it can be difficult to assess the severity of mitral regurgitation (MR), as they present with a prolapsing volume (i.e. volume resulting from mitral valve prolapse, blood volume shift) rather than a regurgitant jet. Read More

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Transcatheter mitral valve interventions: pre-procedural planning and intra-procedural guidance.

Minerva Cardiol Angiol 2021 May 4. Epub 2021 May 4.

Cardiovascular Imaging Unit, San Raffaele Hospital, Milan, Italy -

Mitral regurgitation is the most prevalent valve disease worldwide. Percutaneous mitral valve interventions are emerging as alternative options for high-risk patients with severe mitral regurgitation not eligible for conventional surgery. Accurate patient selection is based on a detailed pre-procedural multimodality imaging evaluation. Read More

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Transcatheter mitral valve repair in a high-surgical risk patient with severe degenerative mitral regurgitation using the novel DragonFly™ Transcatheter Repair device-First in man implantation in China.

Catheter Cardiovasc Interv 2021 May 4. Epub 2021 May 4.

Department of Cardiology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Transcatheter repair of mitral regurgitation (MR) by edge-to-edge therapy has become increasingly accepted for patients with severe MR at high or prohibitive surgical risk in primary or degenerative mitral regurgitation (DMR). The technological approach has evolved from the initial transcatheter edge-to-edge device to improve on its acute reduction in MR and durability of results, particularly in complex primary pathology. In this study, we reported the first case of DragonFly™ Transcatheter Valve Repair device in a patient with severe DMR. Read More

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What Factors Should Be Considered to Improve Outcome of Mechanical Mitral Valve Replacement in Children?

World J Pediatr Congenit Heart Surg 2021 May;12(3):367-374

Department of Cardiovascular Surgery, 4352Mayo Clinic, Rochester, MN, USA.

Objective: To identify risk factors for pediatric mechanical mitral valve replacement (mMVR) to improve management in this challenging population.

Methods: From 1993 to 2019, 93 children underwent 119 mMVR operations (median age, 8.8 years [interquartile range [IQR]: 2. Read More

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Long-term clinical and haemodynamic results after transcatheter annuloplasty for secondary mitral regurgitation.

ESC Heart Fail 2021 May 3. Epub 2021 May 3.

Klinik und Poliklinik für Kardiologie, Universitätsklinikum Leipzig, Liebigstraße 20, Leipzig, 04103, Germany.

Aims: The study sought to investigate the long-term outcome after transcatheter mitral valve annuloplasty for secondary mitral regurgitation (MR).

Methods And Results: Consecutive patients with symptomatic secondary MR undergoing transcatheter mitral valve annuloplasty with the Carillon device at Leipzig University Hospital between 2012 and 2018 were studied prospectively. Left ventricular (LV) function and MR severity were quantified by standardized echocardiography. Read More

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Safety and efficacy outcomes at 1 year after MitraClip therapy for percutaneous mitral valve repair in patients with severe mitral regurgitation: the Egyptian experience.

Egypt Heart J 2021 May 3;73(1):42. Epub 2021 May 3.

Department of Cardiology, Faculty of Medicine, Zagazig University, Zagazig, 44519, Egypt.

Background: Our aim was to assess safety and efficacy outcomes at 1 year after MitraClip for percutaneous mitral valve repair in patients with severe mitral regurgitation. Twenty consecutive patients with significant MR (GIII or GIV) were selected according to the AHA/ACC guidelines from June 2016 to June 2019 and underwent percutaneous edge-to-edge mitral valve repair using MitraClip with a whole 1 year follow-up following the procedure. The primary acute safety endpoint was a 30-day freedom from any of the major adverse events (MAEs) or rehospitalization for heart failure. Read More

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Mitral kissing lesion with anterior mitral leaflet aneurysm in a child.

Ann Card Anaesth 2021 Jan-Mar;24(1):108-110

Department of Cardiac Anasthesia, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India.

Aortic valve endocarditis can lead to secondary involvement of aorto mitral curtain and the adjacent anterior mitral leaflet (AML). The secondary damage to AML is often caused by the infected diastolic jet of aortic regurgitation hitting the ventricular surface of the anterior mitral leaflet, or by the pronounced bacterial vegetation that prolapses from the aortic valve into the left ventricular outflow tract. This is called "kissing lesion". Read More

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Left atrial thrombus in a case of severe aortic stenosis with severe left ventricular dysfunction: An Incidental finding on transesophageal echocardiography.

Ann Card Anaesth 2021 Jan-Mar;24(1):87-89

Department of Cardiovascular and Thoracic Surgery, SGPGIMS, Lucknow, Uttar Pradesh, India.

Left atrial thrombus in a patient with aortic stenosis and aortic regurgitation in sinus rhythm is an infrequent finding and is most commonly associated with cases of mitral stenosis. This case report emphasizes upon the importance of suspecting the presence of left atrial thrombus in other valvular lesions when additional risk factors such as dilated left ventricle are present. The undeniable role of comprehensive perioperative transesophageal echocardiography is also depicted in this case report. Read More

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Windsock deformity of submitral left ventricular aneurysm communicating into left atrium - role of transesophageal echocardiography.

Ann Card Anaesth 2021 Jan-Mar;24(1):72-74

Department of Cardiothoracic and Vascular Surgery, Kerala Institute of Medical Sciences, Trivandrum, Kerala, India.

Submitral left ventricular aneurysm (SMLA) is a rare condition. We report here a 38-year-old male patient, presented with mitral regurgitation and features of congestive cardiac failure (CCF) with New York Heart Association (NYHA) function class III, diagnosed to have SMLA. We discuss here the etiology, types, clinical presentation, and management of SMLA and also the role of transesophageal echocardiography in diagnosis. Read More

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Changes in left ventricular and atrial mechanics and function after dialysis in patients with end-stage renal disease.

Quant Imaging Med Surg 2021 May;11(5):1899-1908

Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Background: Hemodialysis (HD) can influence end-stage renal disease (ESRD) patients' circulatory system. The present study aimed to evaluate the effect of volume depletion on left ventricular (LV) and left atrial (LA) function and determine the volume-independent parameters before and after HD in patients with ESRD.

Methods: Between January 2018 and January 2019, we recruited long-term HD patients (n=40, 51. Read More

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Clinical implications of left atrial size adjustment: Impact of obesity.

Arch Cardiovasc Dis 2021 Apr 29. Epub 2021 Apr 29.

Department of Cardiology, University of Ottawa Heart Institute, Ottawa, Canada. Electronic address:

Background: American and European societies recommend using left atrial (LA) volume adjusted to body surface area (BSA) as the means of indexing LA volume to the patient's body size irrespective of morphometric characteristics.

Aim: To evaluate the impact of obesity on LA volume indexation to BSA on the presence and degree of LA enlargement.

Methods: From our echocardiography database, we extracted all consecutive adults referred for a transthoracic echocardiography in 2019 (n=28,725; 64±17 years; 55% male; 31% obese [body mass index≥30kg/m]). Read More

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Left ventricular remodelling and prognosis after discharge in new-onset acute heart failure with reduced ejection fraction.

ESC Heart Fail 2021 May 2. Epub 2021 May 2.

Department of Cardiology, Erasmus MC, University Medical Center Rotterdam, Dr. Molewaterplein 40, Room Rg4, PO Box 2040, Rotterdam, 3015 GD, The Netherlands.

Aims: This study aimed to investigate the left ventricular (LV) remodelling and long-term prognosis of patients with new-onset acute heart failure (HF) with reduced ejection fraction who were pharmacologically managed and survived until hospital discharge. We compared patients with ischaemic and non-ischaemic aetiology.

Methods And Results: This cohort study consisted of 111 patients admitted with new-onset acute HF in the period 2008-2016 [62% non-ischaemic aetiology, 48% supported by inotropes, vasopressors, or short-term mechanical circulatory devices, and left ventricular ejection fraction (LVEF) at discharge 28% (interquartile range 22-34)]. Read More

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Left atrial assist device for heart failure with preserved ejection fraction: initial results with torque control mode in diastolic heart failure model.

Heart Fail Rev 2021 May 1. Epub 2021 May 1.

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.

A novel pump, the left atrial assist device (LAAD), is a device specifically for the treatment of heart failure with preserved ejection fraction (HFpEF). The LAAD is a mixed-flow pump that is implanted in the mitral position and delivers blood from the left atrium to the left ventricle. During the development process, we aimed to explore whether device activation in torque control (TC) mode would improve the function of the LAAD. Read More

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Bicuspidized De Vega for functional tricuspid valve regurgitation: "De-Kay repair".

Ann Thorac Surg 2021 Apr 27. Epub 2021 Apr 27.

Department of Cardiovascular Science, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome.

Functional tricuspid valve regurgitation in the contest of mitral valve disease is a highly prevalent disease. We describe a ring-less technique that combines restrictive annuloplasty (De Vega) with posterior tricuspid leaflet obliteration (Kay) used for patients with less-than-severe functional tricuspid valve regurgitation undergoing mitral valve surgery. The technique has been in use at our centre since 2012, showing promising long-term echocardiographic results, with stable reduction of the annulus size and stable reduction of the degree of regurgitation. Read More

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10-year results of mitral repair and coronary bypass for ischemic regurgitation: a randomized trial.

Ann Thorac Surg 2021 Apr 27. Epub 2021 Apr 27.

GVM Care&Research, Dept of Cardiovascular Surgery, Maria Eleonora Hospital, Palermo (PA), Italy; GVM Care&Research, Maria Cecilia Hospital, Cotignola (RA), Italy. Electronic address:

Background: The decision to treat moderate ischemic mitral regurgitation (IMR) at the time of coronary artery bypass surgery (CABG) remains controversial. We previously conducted a prospective randomized trial that showed a benefit of adding restricted annuloplasty to bypass surgery (CABG-Ring group) in terms of ischemic mitral regurgitation (IMR) grade, NYHA classification, and left ventricle reverse remodeling. Here, we present the long-term (>10 years) follow-up data from this randomized trial. Read More

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Transcatheter Mitral Valve Repair for Primary and Secondary Mitral Regurgitation: New insights from a Nationwide Registry.

Eur J Heart Fail 2021 Apr 30. Epub 2021 Apr 30.

Cardiology Department, Bichat Hospital, AP-, HP, Paris, France.

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Association between calcification of mitro-aortic continuity and mitral regurgitation in patients undergoing transcatheter aortic valve replacement.

Kardiol Pol 2021 Apr 29. Epub 2021 Apr 29.

Background: Presence of mitral annular calcification (MAC) affects prognosis in patients undergoing transcatheter aortic valve implantation (TAVI). MAC frequently coexists with calcifications of mitro-aortic continuity (CMAC).

Aims: We aimed at qualitative and semi-quantitative analysis of calcifications of the mitral complex - MAC and CMAC in multi-slice computed tomography, in order to assess their impact on the occurrence and dynamics of mitral regurgitation (MR) following TAVI. Read More

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A Case of Atypical Bartonellosis in a 4-Year-Old Immunocompetent Child.

Microorganisms 2021 Apr 28;9(5). Epub 2021 Apr 28.

Pediatric Clinic, Pietro Barilla Children's Hospital, University of Parma, Via Gramsci 14, 43126 Parma, Italy.

In most cases, infection due to causes a mild disease presenting with a regional lymphadenopathy frequently associated with a low-grade fever, headache, poor appetite and exhaustion that spontaneously resolves itself in a few weeks. As the infection is generally transmitted by cats through scratching or biting, the disease is named cat scratch disease (CSD). However, in 5-20% of cases, mainly in immunocompromised patients, systemic involvement can occur and CSD may result in major illness. Read More

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Predicting Long-Term Mortality in TAVI Patients Using Machine Learning Techniques.

J Cardiovasc Dev Dis 2021 Apr 16;8(4). Epub 2021 Apr 16.

Centro Cardiologico Monzino, IRCCS, 20138 Milan, Italy.

Background: Whereas transcatheter aortic valve implantation (TAVI) has become the gold standard for aortic valve stenosis treatment in high-risk patients, it has recently been extended to include intermediate risk patients. However, the mortality rate at 5 years is still elevated. The aim of the present study was to develop a novel machine learning (ML) approach able to identify the best predictors of 5-year mortality after TAVI among several clinical and echocardiographic variables, which may improve the long-term prognosis. Read More

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