31,480 results match your criteria Mitral Regurgitation


[Isolated Mitral Valve Replacement was Effective in Patient with Hypertrophic Obstructive Cardiomyopathy and Concomitant Mitral Regurgitation;Report of a Case].

Kyobu Geka 2019 Feb;72(2):149-152

Department of Cardiovascular Surgery, Hokuto Hospital, Obihiro, Japan.

This report presents a case of a 68-year-old woman with hypertrophic obstructive cardiomyopathy (HOCM) and concomitant mitral regurgitation (MR). Preoperative echocardiography showed stenosis of the left ventricular outflow tract (LVOT) and systolic anterior leaflet motion (SAM) of the mitral valve. She underwent mitral valve replacement( MVR) alone, and obstruction of LVOT was successfully released. Read More

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February 2019

[Giant Aneurysm of the Left Sinus of Valsalva Accompanied by Left Main Coronary Artery Compression, Myocardial Ischemia, Pericardial Tamponade].

Kyobu Geka 2019 Feb;72(2):99-103

Department of Cardiovascular Surgery, Yokkaichi Municipal Hospital, Yokkaichi, Japan.

Left sinus of Valsalva aneurysm(SVAn)is a very rare clinical entity. We present a 68-year-old female with left SVAn, 5 cm in diameter, compressing the left main coronary artery and causing antero-septal asynergy. She also had massive pericardial effusion, moderate to severe(grade Ⅲ)aortic regurgitation, and mitral regurgitation. Read More

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February 2019

Valve area and the risk of overestimating aortic stenosis.

Heart 2019 Feb 16. Epub 2019 Feb 16.

Department of Cardiology, Hospital General Universitario Gregorio Maranon, Madrid, Spain.

Objective: To obtain reference values of aortic valve area (AVA) in a large population and to infer the risk of overestimating aortic stenosis (AS) when focusing on flow-corrected indices of severity.

Methods: We prospectively measured indices of AS in all consecutive echocardiograms performed in a large referral cardiac imaging laboratory for 1 year. We specifically analysed the distribution of AVA, indexed AVA and velocity ratio (Vratio) in patients with and without AS, the latter defined as the coexistence of valvular outflow obstruction (Vmax ≥2. Read More

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http://dx.doi.org/10.1136/heartjnl-2018-314482DOI Listing
February 2019

Echocardiographic guidance for transcatheter mitral valve repair using edge-to-edge clip.

J Echocardiogr 2019 Feb 15. Epub 2019 Feb 15.

Division of Cardiology, Department of Internal Medicine, University of California, Davis, 4860 Y Street, Suite 2820, Sacramento, CA, 95817, USA.

Percutaneous intervention for mitral valve disease has been established as an alternative to open surgical repair in high risk and inoperable candidates. Edge-to-edge leaflet plication with Mitraclip (Abbott, Menlo Park, CA, USA) is indicated for primary and secondary mitral valve diseases. Echocardiography provides a better understanding of mitral valve anatomy and allows us to classify and quantify mitral regurgitation. Read More

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http://dx.doi.org/10.1007/s12574-019-00417-0DOI Listing
February 2019

Commentary: Repair for ischemic mitral valve regurgitation: Does the type of ring matter?

Authors:
Manuel J Antunes

J Thorac Cardiovasc Surg 2019 Jan 23. Epub 2019 Jan 23.

Faculty of Medicine of the University of Coimbra, Coimbra, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.jtcvs.2019.01.037DOI Listing
January 2019

The Correlation between Severity of Neurological Impairment and Left Ventricular Function in Patients after Acute Ischemic Stroke.

J Clin Med 2019 Feb 5;8(2). Epub 2019 Feb 5.

Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University, Kaohsiung 83301, Taiwan.

Despite left ventricular (LV) dysfunction increases the risk of incidental acute ischemic stroke (AIS), the association between LV function and severity of neurological deficits after AIS remains unclear. Between November 2015 and October 1017, a total of 99 AIS patients were prospectively enrolled and categorized into two groups based on National Institute of Health Stroke Scale (NIHSS). The AIS patients with NIHSS <6 were allocated into Group 1 ( = 50) and those with NIHSS ≥6 were into Group 2 ( = 49). Read More

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http://dx.doi.org/10.3390/jcm8020190DOI Listing
February 2019

Recommendations on the use of innovative medical technologies in cardiology and cardiac surgery and solutions leading to increased availability for Polish patients.

Cardiol J 2019 Feb 14. Epub 2019 Feb 14.

Abbott Health Economics & Reimbursement.

There is a great need for innovative technologies that will improve the health and quality of life (QoL) of Polish patients with cardiac problems. It is important that the safety and effectiveness of the technology are confirmed by scientific evidence on which guidelines and clinical recommendations are based. Scientific evidence for medical devices is also increasingly important for decision-making in finance approval from public funds. Read More

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http://dx.doi.org/10.5603/CJ.a2019.0007DOI Listing
February 2019

Cardiac Manifestations in Systemic Lupus Erythematosus: Clinical Correlates of Subclinical Echocardiographic Features.

Biomed Res Int 2019 10;2019:2437105. Epub 2019 Jan 10.

Rheumatology Department, Faculty of Medicine, Cairo University, Giza, Egypt.

Objectives: This study aims to correlate subclinical echocardiographic features with the clinical, laboratory, and therapeutic profiles of the patients to characterize risks for systemic lupus erythematosus (SLE) cardiac diseases.

Methods: The study included 59 SLE patients. Demographic data, disease characteristics, and current therapies were recorded, and the anthropometric measurements and routine laboratory tests were performed. Read More

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http://dx.doi.org/10.1155/2019/2437105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348873PMC
January 2019

Short Term Outcome of Cardiac Resynchronization Therapy on Functional Recovery of Patients with Congestive Heart Failure in Bangladeshi Population.

Mymensingh Med J 2019 Jan;28(1):105-113

Dr Umme Habiba Ferdaushi, Assistant Registrar, Department of Cardiology, National Institute of Cardiovascular Diseases (NICVD), Dhaka, Bangladesh.

Cardiac resynchronization therapy (CRT) reduces symptoms and improves left ventricular function in patients with heart failure due to left ventricular systolic dysfunction and cardiac dyssynchrony. We analyzed the clinical and echocardiographic outcome of CRT in heart failure patients. Thirty five (35) heart failure patients were included in this prospective observational study, conducted from February 2015 to February 2016 in the Department of cardiology, National Institute of Cardiology & Vascular Disease (NICVD) hospital, Dhaka, Bangladesh. Read More

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January 2019

Left ventricular mechanical dispersion predicts arrhythmic risk in mitral valve prolapse.

Heart 2019 Feb 12. Epub 2019 Feb 12.

Division of Cardiovascular Medicine, University of California, San Francisco, San Francisco, California, USA.

Objective: Bileaflet mitral valve prolapse (MVP) with either focal or diffuse myocardial fibrosis has been linked to ventricular arrhythmia and/or sudden cardiac arrest. Left ventricular (LV) mechanical dispersion by speckle-tracking echocardiography (STE) is a measure of heterogeneity of ventricular contraction previously associated with myocardial fibrosis. The aim of this study is to determine whether mechanical dispersion can identify MVP at higher arrhythmic risk. Read More

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http://dx.doi.org/10.1136/heartjnl-2018-314269DOI Listing
February 2019

Re: Persistent reduction of patient's mitral regurgitation by implantation of transannular mitral bridge: durability and effectiveness of the repair at 2 years-results of a prospective trial.

Eur J Cardiothorac Surg 2019 Feb 6. Epub 2019 Feb 6.

Department of Cardiothoracic Surgery, University Hospital of Wales, Cardiff, UK.

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http://dx.doi.org/10.1093/ejcts/ezz024DOI Listing
February 2019

Can complex mitral valve repair be performed with robotics? An institution's experience utilizing a dedicated team approach in 500 patients.

Eur J Cardiothorac Surg 2019 Feb 11. Epub 2019 Feb 11.

Department of Cardiothoracic Surgery, Division of Cardiac Surgery, NYU Langone Health, New York, NY, USA.

Objectives: The full potential of robotics has not been achieved in terms of addressing the most challenging mitral valve (MV) cases. We outline our technique and report our early results with totally endoscopic robotic MV repair in a wide range of pathologies.

Methods: From May 2011 to August 2017, a dedicated team attempted totally endoscopic robotic MV repair in 500 MV regurgitation patients. Read More

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http://dx.doi.org/10.1093/ejcts/ezz029DOI Listing
February 2019
2 Reads

[Treatment of secondary ischemic mitral regurgitation: controversial issues].

G Ital Cardiol (Rome) 2019 Feb;20(2):97-108

Centro Cardiologico Universitario e LTTA Centre, Università degli Studi, Ferrara - Maria Cecilia Hospital, GVM Care & Research, E.S. Health Science Foundation, Cotignola (RA).

The presence of secondary mitral regurgitation is an unfavorable prognostic factor in patients with chronic ischemic heart disease. This type of regurgitation can be treated with medical therapy, cardiac resynchronization therapy, surgically or percutaneously but each strategy has controversial aspects. The purpose of this review is to discuss the most debated issues relative to the various modalities available to treat ischemic secondary mitral regurgitation, highlighting also future perspectives. Read More

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http://dx.doi.org/10.1714/3093.30857DOI Listing
February 2019

Mitral Prolapse: An Old Mysterious Entity - The Incremental Role of Multimodality Imaging in Sports Eligibility.

J Cardiovasc Echogr 2018 Oct-Dec;28(4):207-217

Luigi Vanvitelli University, Monaldi Hospital, AORN Ospedali Dei Colli, Naples, Italy.

Mitral valve prolapse is generally a benign condition characterized by fibromyxomatous changes of the mitral leaflet with displacement into the left atrium and late-systolic regurgitation. Although it is an old clinical entity, it still arouses perplexity in diagnosis and clinical management. Complications, such as mitral regurgitation (MR), atrial fibrillation, congestive heart failure, endocarditis, ventricular arrhythmias, and sudden cardiac death (SCD), have been reported. Read More

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http://dx.doi.org/10.4103/jcecho.jcecho_42_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341849PMC
February 2019
1 Read

Clinical manifestations, diagnosis, and treatment of ischemic mitral regurgitation: a review.

J Thorac Dis 2018 Dec;10(12):6969-6986

Department of Cardiology, Hospital Universitario de Canarias, Tenerife, Spain.

Ischemic mitral regurgitation (IMR) is a frequent complication after acute myocardial infarction (AMI) associated with a worse prognosis. The pathophysiological mechanisms of IMR are not fully understood, but it is known to be a complex process in which ventricular remodelling is the main causal factor. The various imaging techniques in cardiology and echocardiography fundamentally have contributed significantly to clarify the mechanisms that cause and progressively aggravate IMR. Read More

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http://jtd.amegroups.com/article/view/25085/19483
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http://dx.doi.org/10.21037/jtd.2018.10.64DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344722PMC
December 2018
3 Reads

Outcomes of Transcatheter Aortic Valve Implantation in Patients with Cirrhosis.

Int Heart J 2019 Feb 8. Epub 2019 Feb 8.

Department of Cardiology, Sakakibara Heart Institute.

Cirrhosis is a significant adverse factor of cardiac surgeries. Transcatheter aortic valve implantation (TAVI) has evolved as a less invasive therapy for aortic stenosis, whereas detailed case analysis of TAVI in cirrhotic patients is limited.Among 444 consecutive patients who underwent TAVI in the Sakakibara Heart Institute between October 2013 and January 2018, we retrospectively reviewed 11 patients (2. Read More

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https://www.jstage.jst.go.jp/article/ihj/advpub/0/advpub_18-
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http://dx.doi.org/10.1536/ihj.18-339DOI Listing
February 2019
2 Reads

Extended Posterior Leaflet Augmentation for Ischemic Mitral Regurgitation - Augmented Posterior Leaflet Snuggling up to Anterior Leaflet.

Circ J 2019 Feb 9. Epub 2019 Feb 9.

Department of Cardiovascular Surgery, Showa University Koto Toyosu Hospital.

Background: The ideal surgical technique for ischemic mitral regurgitation (MR) is controversial. We introduced an extended posterior mitral leaflet (PML) augmentation technique for functional MR with severe tethering, which detached the PML from the annulus almost completely and augmented it with a large 3×6-cm oval pericardial patch. Methods and Results: A total of 17 mitral repairs using the new technique were performed for ischemic MR with no 30-day mortality and 2 hospital deaths. Read More

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http://dx.doi.org/10.1253/circj.CJ-18-0849DOI Listing
February 2019

Multidisciplinary decision-making in mitral valve disease: the mitral valve heart team.

Neth Heart J 2019 Feb 11. Epub 2019 Feb 11.

Department of Cardiothoracic Surgery, Maastricht University Medical Centre, Maastricht, The Netherlands.

Background: Although decision-making using the heart-team approach is apparently intuitive and has a class I recommendation in most recent guidelines, supportive data is still lacking. The current study aims to demonstrate the individualised clinical pathway for mitral valve disease patients and to evaluate the outcome of all patients referred to the dedicated mitral valve heart team.

Methods: All patients who were evaluated for mitral valve pathology with or without concomitant cardiac disease between 1 January 2016 and 31 December 2016 were prospectively followed and included. Read More

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http://dx.doi.org/10.1007/s12471-019-1238-1DOI Listing
February 2019
1 Read

Radial versus Femoral Approach for Left Ventricular Endomyocardial Biopsy.

EuroIntervention 2019 Feb 12. Epub 2019 Feb 12.

London Health Sciences Centre, London, Ontario, Canada.

Aims: Left ventricular endomyocardial biopsy (LV-EMB) is mostly performed via the femoral artery. We assessed the feasibility and safety of radial versus femoral access in patients undergoing LV-EMB.

Methods And Results: 264 patients from four countries undergoing LV-EMB were collected. Read More

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http://dx.doi.org/10.4244/EIJ-D-18-01061DOI Listing
February 2019

Cluster analysis of preoperative echocardiographic findings and outcomes following left ventricular device implantation.

J Thorac Cardiovasc Surg 2018 Dec 11. Epub 2018 Dec 11.

Department of Cardiac Surgery, University of Michigan Frankel Cardiovascular Center, Ann Arbor, Mich.

Objective: To investigate whether preoperative echocardiography findings determine postoperative continuous-flow left ventricular assist device outcomes.

Methods: From January 2003 to June 2017, 490 patients received a durable, continuous-flow left ventricular assist device. Two-step clustering of parameters including heart rate and preoperative echocardiographic findings (ie, left ventricular [LV] ejection fraction, right ventricular [RV] function, aortic insufficiency, mitral regurgitation [MR], tricuspid regurgitation [TR]) was performed and identified 5 distinct clusters associated with LV failure: group 1: moderate right ventricular dysfunction (RVD), severe MR and mild TR (n = 110); group 2: severe RVD, severe MR and TR (n = 64); group 3: moderate RVD and severe aortic insufficiency (n = 16); group 4: mild RVD and mild valvular pathology (n = 163); and group 5: moderate-severe RVD and mild valvular pathology (n = 137). Read More

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http://dx.doi.org/10.1016/j.jtcvs.2018.11.099DOI Listing
December 2018
1 Read

Midrange ejection fraction as a risk factor for deterioration of cardiofunction after permanent pacemaker implantation.

J Interv Card Electrophysiol 2019 Feb 9. Epub 2019 Feb 9.

Department of Emergency Cardiology, Beijing Anzhen Hospital, Capital Medical University, Anzhen Road Second, Chaoyang District, Beijing, 100029, People's Republic of China.

Purpose: To determine whether the midrange ejection fraction (mrEF) is associated with increased risk of deterioration of cardiac function (DCF) after dual chamber permanent pacemaker (PPM) implantation.

Methods: We performed a prospective cohort study of relevance in patients with EF ≥ 40% and indications for PPMs. Patient characteristics were recorded at baseline and 1 day, 1 month, 3 months, and 6 months after PPM implantation with leads placed in the right ventricular apex. Read More

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http://dx.doi.org/10.1007/s10840-019-00513-2DOI Listing
February 2019
1 Read

Electropharmacological effects of intracellular Ca handling modulator caldaret on the heart assessed in the halothane-anesthetized dogs.

J Pharmacol Sci 2019 Jan 24. Epub 2019 Jan 24.

Department of Pharmacology, Faculty of Medicine, Toho University, 5-21-16 Omori-nishi, Ota-ku, Tokyo 143-8540, Japan; Department of Pharmacology, Toho University Graduate School of Medicine, 5-21-16 Omori-nishi, Ota-ku, Tokyo 143-8540, Japan.

We analyzed how the enhancement of net sarcoplasmic reticulum (SR) Ca uptake may affect cardiac electrophysiological properties in vivo by using caldaret which can decrease SR diastolic Ca leak, enhance SR Ca reuptake and inhibit reverse-mode Na/Ca exchanger. Caldaret in doses of 0.5, 5 and 50 μg/kg was intravenously administered over 10 min to the halothane-anesthetized beagle dogs (n = 5), attaining pharmacologically active plasma concentration. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13478613193000
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http://dx.doi.org/10.1016/j.jphs.2019.01.004DOI Listing
January 2019
2 Reads

Paravalvular leak repair after balloon-expandable transcatheter mitral valve implantation in mitral annular calcification: Early experience and lessons learned.

Catheter Cardiovasc Interv 2019 Feb 9. Epub 2019 Feb 9.

Department of Cardiovascular Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minnesota.

Background: Treatment of hemodynamically significant mitral annular calcification (MAC) using transcatheter approaches is in the early learning phase. The occurrence of paravalvular leak (PVL) following transcatheter mitral valve in MAC is common.

Aims: To report the initial experience and techniques of percutaneous PVL closure after transcatheter valve in MAC. Read More

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http://doi.wiley.com/10.1002/ccd.28131
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http://dx.doi.org/10.1002/ccd.28131DOI Listing
February 2019
2 Reads

Comprehensive Nursing Management for Valvular Disease.

Authors:
Susan Lee

Crit Care Nurs Clin North Am 2019 Mar 22;31(1):31-38. Epub 2018 Dec 22.

School of Nursing, Louisiana State University Health, 1900 Gravier Street, Room 328, New Orleans, LA 70112, USA. Electronic address:

Valvular heart dysfunction (VHD) affects up to 7% of adults up to age 44 year, whereas up to 13% of individuals older than 75 years are affected. The broad term of valvular heart disease includes dysfunction of one or more of the 4 heart valves, including the pulmonary valve, tricuspid valve, mitral valve, or aortic valve. Specifically the more frequent anomalies, implication, assessment, and treatment that will be described more extensively include aortic regurgitation, aortic stenosis, mitral regurgitation, or tricuspid regurgitation. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08995885183100
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http://dx.doi.org/10.1016/j.cnc.2018.11.002DOI Listing
March 2019
3 Reads

Transprosthetic cuff leakage of a bovine pericardial aortic bioprosthesis.

Semin Thorac Cardiovasc Surg 2019 Feb 4. Epub 2019 Feb 4.

Department of Cardiovascular Surgery, The Sakakibara Heart Institute of Okayama, Japan.

Objective: The Carpentier-Edwards PERIMOUNT Magna aortic heart valve is the most frequently implanted bioprosthesis. However, the existence of transvalvular cuff leakage necessitating a second cross clamp has been recently reported. The aim of this study is to seek the mechanism, occurrence rate, and influence of cuff leakage on the clinical course. Read More

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http://dx.doi.org/10.1053/j.semtcvs.2019.02.007DOI Listing
February 2019
1 Read

Cardiac Remodeling in Aortic and Mitral Valve Disease - a Simulation Study with Clinical Validation.

J Appl Physiol (1985) 2019 Feb 7. Epub 2019 Feb 7.

ECMO Department, Karolinska University Hospital, Stockholm, Sweden.

Background: Remodeling is an important long-term determinant of cardiac function throughout the progression of heart disease. Numerous biomolecular pathways for mechanosensing and transduction are involved. However, we hypothesize that biomechanical factors alone can explain changes in myocardial volume and chamber size in valve disease. Read More

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https://www.physiology.org/doi/10.1152/japplphysiol.00791.20
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http://dx.doi.org/10.1152/japplphysiol.00791.2018DOI Listing
February 2019
12 Reads

Early mitral inflow velocity to left ventricular global strain ratio predicts limited exercise capacity.

Echocardiography 2019 Feb 6. Epub 2019 Feb 6.

Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Science, Hiroshima, Japan.

Background: Estimation of left ventricular filling pressure (LVFP) is the essential part of the echocardiographic workup for exercise intolerance. The ratio of the mitral early filling velocity to the left ventricular global longitudinal strain (E/LVGLS) has emerged as a novel index of LVFP. This study aimed to investigate the relationship between E/LVGLS and exercise capacity. Read More

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http://dx.doi.org/10.1111/echo.14263DOI Listing
February 2019

Association of Structural and Functional Cardiac Changes With Transcatheter Aortic Valve Replacement Outcomes in Patients With Aortic Stenosis.

JAMA Cardiol 2019 Feb 6. Epub 2019 Feb 6.

Division of Cardiovascular Diseases, Department of Internal Medicine, Heart & Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.

Importance: Severe aortic stenosis causes pressure overload of the left ventricle, resulting in progressive cardiac dysfunction that can extend beyond the left ventricle. A staging system for aortic stenosis has been recently proposed that quantifies the extent of structural and functional cardiac changes in aortic stenosis.

Objectives: To confirm the reproducibility of a proposed staging system and expand the study findings by performing a survival analysis and to evaluate the association of aortic stenosis staging with both cardiac and noncardiac post-transcatheter aortic valve replacement (TAVR) readmissions. Read More

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http://dx.doi.org/10.1001/jamacardio.2018.4830DOI Listing
February 2019
1 Read

[The personalized approach to the rehabilitation of a severely ill patient presenting with a cardio-surgical problem].

Vopr Kurortol Fizioter Lech Fiz Kult 2019 ;96(1):50-54

Research Institute of Complex Problems of Cardio-Vascular Diseases, Kemerovo, Russia.

The ever increasing number of the patients presenting with the cardio-surgical problems referred for surgery emphasizes the importance of the treatment of the cases of post-operative complications based on the personalized approach. The present article was designed to report a clinical case of the successful surgical treatment and rehabilitation of a patient presenting with the dysfunction of the bioprosthetic mitral valve and complications of the post-operative course in the form of polyorgan insufficiency with the predominance of respiratory failure. Special attention is given to the post-operative complications among which the respiratory insufficiency prevailed that made necessary the long period of artificial pulmonary ventilation. Read More

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http://dx.doi.org/10.17116/kurort20199601150DOI Listing
January 2019
2 Reads

Monitoring pulmonary artery pressures in chronic heart failure patients and evaluating treatment effect of MitraClip implantation for functional mitral regurgitation.

EuroIntervention 2019 Feb 5. Epub 2019 Feb 5.

Erasmus MC, University Medical Center Rotterdam, Thorax Center, department of Cardiology, Rotterdam, the Netherlands.

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http://dx.doi.org/10.4244/EIJ-D-18-01188DOI Listing
February 2019
1 Read

Left Atrial Dysfunction as an Independent Correlate of Heart Failure Symptoms in Patients With Severe Aortic Stenosis and Preserved Left Ventricular Ejection Fraction.

J Am Soc Echocardiogr 2019 Feb;32(2):257-266

University of Medicine and Pharmacy "Carol Davila," Euroecolab, Bucharest, Romania; Emergency Institute of Cardiovascular Diseases "Prof. Dr. C. C. Iliescu", Bucharest, Romania. Electronic address:

Background: Data regarding the contribution of left atrial (LA) dysfunction to the occurrence of heart failure in patients with severe aortic stenosis (AS) are scarce. The aim of this study was to assess the relationship between LA deformation and symptomatic status in this clinical setting.

Methods: A total of 361 consecutive patients with severe AS (aortic valve area [AVA] index ≤ 0. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08947317183064
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http://dx.doi.org/10.1016/j.echo.2018.11.007DOI Listing
February 2019
6 Reads

Atrioventricular valves dysplasia in a newborn.

Cardiol Young 2019 Feb 4:1-3. Epub 2019 Feb 4.

Congenital Cardiac Surgery - Hospital Universitario "12 de Octubre",Avenida de Cordoba,s/n, 28041,Madrid,Spain.

A newborn with prenatally diagnosed dysplasia of both atrioventricular valves presented after birth with signs and symptoms of low cardiac output, severe regurgitation of both mitral and tricuspid valves. This combination is as rare as challenging, since it regards both the timing and management of this complex cardiac malformation. We report an early surgical repair of both atrioventricular valves in a symptomatic newborn, which improved his clinical status and, so far, delayed valve replacement. Read More

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http://dx.doi.org/10.1017/S1047951118002524DOI Listing
February 2019
1 Read

Predictive Factors for Progression of Mitral Regurgitation in Asymptomatic Patients With Mitral Valve Prolapse.

Am J Cardiol 2019 Jan 24. Epub 2019 Jan 24.

The Division of Cardiology, Department of Medicine, University of California, Sulpizio Cardiovascular Center, San Diego, California. Electronic address:

Risk factors predicting progression from low grade to severe mitral regurgitation (MR), which is a guideline criterion for surgical intervention, remain unknown. We hypothesized that abnormalities of cardiac structure and function may predict progression in MR severity. We followed 82 asymptomatic mitral valve prolapse (MVP) patients (65 ± 12 years, 51% men) with mild or moderate MR (36 mild, 46 moderate, mean LVEF: 62%), without significant co-morbidities. Read More

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http://dx.doi.org/10.1016/j.amjcard.2019.01.026DOI Listing
January 2019
1 Read

10-year outcomes after left ventricular reconstruction: rethinking the impact of mitral regurgitation.

Ann Thorac Surg 2019 Jan 30. Epub 2019 Jan 30.

Department of Cardiothoracic Surgery, Leiden University Medical Center, Leiden, The Netherlands.

Background: Heart failure with reduced ejection fraction due to a post-infarction anteroseptal aneurysm carries a poor prognosis. Patients with refractory heart failure may be considered for advanced surgery, including left ventricular assist device implantation, heart transplantation and LV reconstruction. Aim of this study was to evaluate outcomes after an integrated approach of left ventricular reconstruction with concomitant procedures (mitral/tricuspid valve repair, coronary revascularization), and assess risk factors for event-free survival, focusing on left ventricular geometry/function and presence of functional mitral regurgitation(MR). Read More

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http://dx.doi.org/10.1016/j.athoracsur.2019.01.003DOI Listing
January 2019
1 Read

[Cardiomyopathy in a 22-year-old man with a long history of methamphetamine abuse].

Internist (Berl) 2019 Feb 1. Epub 2019 Feb 1.

Klinik für Kardiologie, Angiologie und Pneumologie, Innere Medizin III, Medizinische Klinik, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Deutschland.

This article presents the case of a 22-year-old male patient with cardiomyopathy associated with a long history of methamphetamine abuse. Echocardiography revealed a dilated cardiomyopathy with highly reduced systolic pump function and severe mitral valve regurgitation. Inotropic treatment and MitraClip® (Abbott Vascular, Santa Clara, CA, USA) implantation resulted in enhancement of hemodynamics. Read More

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http://link.springer.com/10.1007/s00108-019-0559-x
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http://dx.doi.org/10.1007/s00108-019-0559-xDOI Listing
February 2019
2 Reads

Subclinical carotid atherosclerosis predicts all-cause mortality and cardiovascular events in obese patients with negative exercise echocardiography.

World J Cardiol 2019 Jan;11(1):24-37

Department of Cardiology, Hospital Universitario Lucus Augusti, Lugo 27003, Spain.

Background: Obesity is a major health problem due to its high prevalence. The relationship between obesity and cardiovascular disease is unclear. Some studies agree that certain conditions associated with obesity, such as physical inactivity or cardiovascular risk factors, are responsible for cardiovascular risk excess among obese people. Read More

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https://www.wjgnet.com/1949-8462/full/v11/i1/24.htm
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http://dx.doi.org/10.4330/wjc.v11.i1.24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354075PMC
January 2019
7 Reads

Group A streptococcus endocarditis in children: 2 cases and a review of the literature.

BMC Infect Dis 2019 Jan 31;19(1):102. Epub 2019 Jan 31.

Okinawa Prefectural Nanbu Medical Center & Children's Medical Center, Department of General Pediatrics, Okinawa, Japan.

Background: Infective endocarditis (IE) is defined as endocarditis caused by microorganisms (bacteria or fungi) involving either the heart or great vessels. The clinical course of IE can be complicated by cardiac dysfunction and bacterial embolization to virtually any organ. Staphylococcus aureus and viridans group streptococci are the most common causative organisms, whereas group A Streptococcus (GAS) is less common. Read More

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http://dx.doi.org/10.1186/s12879-019-3736-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357504PMC
January 2019
2 Reads

Simplified Echocardiography Screening Criteria for Diagnosing and Predicting Progression of Latent Rheumatic Heart Disease.

Circ Cardiovasc Imaging 2019 Feb;12(2):e007928

The Heart Institute, Cincinnati Children's Hospital Medical Center, OH (A.Z.B.).

Background: The 2012 World Heart Federation Criteria are the current gold standard for the diagnosis of latent rheumatic heart disease (RHD). Because data and experience using these criteria have grown, there is opportunity to simplify and develop outcome prediction tools. We aimed to develop a simple echocardiographic score applicable for RHD screening with potential to predict disease progression. Read More

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http://dx.doi.org/10.1161/CIRCIMAGING.118.007928DOI Listing
February 2019
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Differential Transcriptome Profile and Exercise Capacity in Cardiac Remodeling by Pressure Overload versus Volume Overload.

J Cardiovasc Imaging 2019 Jan;27(1):50-63

Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Korea.

Background: We compared the gene expression profiles in the hypertrophied myocardium of rats subjected to pressure overload (PO) and volume overload (VO) using DNA chip technology, and compared the effects on exercise capacity with a treadmill test.

Methods: Constriction of the abdominal aorta or mitral regurgitation induced by a hole in the mitral leaflet were used to induce PO (n = 19), VO (n = 16) or PO + VO (n = 20) in rats. Serial echocardiographic studies and exercise were performed at 2-week intervals, and invasive hemodynamic examination by a pressure-volume catheter system was performed 12 weeks after the procedure. Read More

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http://dx.doi.org/10.4250/jcvi.2019.27.e4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358426PMC
January 2019
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Pattern and Presentation of Thyro-Cardiac Disease among Patients with Hyperthyroidism Attending a Tertiary Hospital in Ethiopia: A Cross Sectional Study.

Ethiop J Health Sci 2019 Jan;29(1):887-894

Department of Internal Medicine, Cardiology Unit, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.

Background: Thyro-cardiac disease describes the existence of a combination of thyroid toxicity and significant heart disease in an individual patient. The frequent manifestations of thyro-cardiac disease are hypertension, atrial flutter or fibrillation, pulmonary hypertension and dilated cardiomyopathy. The aim of the study was to determine the pattern and presentation of cardiovascular diseases in patients with hyperthyroidism on follow-up at St. Read More

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http://dx.doi.org/10.4314/ejhs.v29i1.10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341434PMC
January 2019
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Surgical revision of failed percutaneous edge-to-edge mitral valve repair: lessons learned.

Interact Cardiovasc Thorac Surg 2019 Jan 28. Epub 2019 Jan 28.

Department of Cardiovascular Surgery, Sana-Herzzentrum Cottbus, Cottbus, Germany.

Objectives: Although percutaneous edge-to-edge mitral valve repair with the MitraClip system is becoming widely adopted in clinical practice, surgical experience on how to correct failed MitraClip therapy is limited. We aimed to analyse the surgical and pathological outcomes after surgical revision of the failed MitraClip therapy.

Methods: Between January 2011 and January 2018, 25 patients (age 73 ± 9 years; men 48%; New York Heart Association class 3. Read More

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http://dx.doi.org/10.1093/icvts/ivy361DOI Listing
January 2019
2 Reads

Robotic mitral valve repair: 7-year surgical experience and mid-term follow-up results.

J Cardiovasc Surg (Torino) 2019 Jan 28. Epub 2019 Jan 28.

Department of Cardiovascular Surgery, Institute of Cardiac Surgery, PLA General Hospital, Beijing, China -

Background: The feasibility and safety of robotic mitral valve repair has been proven in several studies but the mid-term to long-term outcomes are unclear. We aim to summarize our surgical experience with robotic mitral valve repair and demonstrate the follow-up results out to 7 years.

Methods: From 2007 to 2014, 110 consecutive patients underwent robotic mitral valve repair with da Vinci Surgical System (Intuitive Surgical, USA) in our center. Read More

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http://dx.doi.org/10.23736/S0021-9509.19.10602-7DOI Listing
January 2019
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Surgical repair of unroofed coronary sinus with severe mitral regurgitation in an elderly patient.

J Cardiol Cases 2019 Jan 22;19(1):29-32. Epub 2018 Oct 22.

Department of Cardiovascular Surgery, Takamatsu Red-Cross Hospital, Kagawa, Japan.

An unroofed coronary sinus (URCS) is a rare anomaly that produces communication between the left atrium (LA) and the coronary sinus (CS), resulting in a left-to-right shunt. Due to the lack of symptoms and particular anatomical characteristics, this disease is difficult to diagnose, and prone to be overlooked. An 85-year-old man was admitted to our hospital because of anorexia and shortness of breath. Read More

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http://dx.doi.org/10.1016/j.jccase.2018.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342724PMC
January 2019
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A case of thrombolytic therapy with recombinant tissue plasminogen activator for mechanical valve thrombosis at 9 weeks of pregnancy in a Japanese woman.

J Cardiol Cases 2019 Jan 17;19(1):15-18. Epub 2018 Sep 17.

Division of Cardiology, Shinshu University Hospital, Nagano, Japan.

A 29-year-old woman was admitted to our hospital due to diagnosis of pregnancy at 5 weeks and a day. She underwent valve replacement with mechanical heart valve (MHV: SJM valve) for congenital mitral valve regurgitation, when 11 years old. Warfarin 4 mg was used for anticoagulation. Read More

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http://dx.doi.org/10.1016/j.jccase.2018.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342610PMC
January 2019
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Graftmaster savior: Injury to a patent LIMA during pericardiectomy, when a covered stent came to the rescue.

Catheter Cardiovasc Interv 2019 Jan 28. Epub 2019 Jan 28.

Penn State Heart and Vascular Institute, Penn State Milton S. Hershey Medical Center, Cardiothoracic Surgery, Hershey, Pennsylvania.

A 71-year-old male with multivessel coronary artery disease who underwent bypass with saphenous vein grafts to a Marginal branch and distal RCA and LIMA to LAD in 1988, DM II, atrial fibrillation on Coumadin, TIA, obstructive sleep apnea and pulmonary hypertension was referred to our institution after extensive dyspnea evaluation with a diagnosis of constrictive pericarditis for pericardiectomy. He had normal left ventricular function, moderate mitral and tricuspid regurgitation. Coronary angiography revealed ostial LAD CTO, patent LIMA to mid LAD, second Marginal branch CTO with left-to-left collaterals and mid RCA CTO with left-to-right collaterals. Read More

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http://dx.doi.org/10.1002/ccd.28100DOI Listing
January 2019
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Mitral Valve Endocarditis: A rare Manifestation of Lyme Disease.

Ann Thorac Surg 2019 Jan 25. Epub 2019 Jan 25.

Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic Foundation, Cleveland, Ohio.

Valvular involvement in Lyme disease is rare. Confirmation of Borrelia species as the causative agent by Polymerase Chain Reaction (PCR) was done in a few cases in Europe and the US. We describe a case of mitral regurgitation with a preoperative diagnosis of myxomatous mitral valve degeneration. Read More

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http://dx.doi.org/10.1016/j.athoracsur.2018.12.046DOI Listing
January 2019
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Thoracoscopic ablation for the treatment of atrial fibrillation: a systematic outcome analysis of a multicentre cohort.

Europace 2019 Jan 25. Epub 2019 Jan 25.

Department of Cardiothoracic Surgery, St. Antonius Hospital, Koekoekslaan 1, CM Nieuwegein, the Netherlands.

Aims: To perform a systematic outcome analysis in order to provide cardiologists and general pactitioners with more adequate information to guide their decision making regarding rhythm control. Totally thoracoscopic maze (TTmaze) for the treatment of atrial fibrillation (AF) is recommended as a Class 2a indication mainly based on single centre studies including small patient cohorts and inconsistent lesion sets.

Methods And Results: We studied consecutive patients undergoing TTmaze in three European referral centres (2012-15). Read More

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http://dx.doi.org/10.1093/europace/euy323DOI Listing
January 2019
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Three-dimensional echocardiography of mitral Barlow's disease with infective endocarditis: Perforations or cleft-like indentations?

J Clin Ultrasound 2019 Jan 28. Epub 2019 Jan 28.

The Department of Cardiovascular Ultrasound, The First Hospital of China Medical University, Shenyang, Liaoning, People's Republic of China.

Barlow's disease is a complicated form of degenerative mitral valve (MV) disease. Infective endocarditis (IE) often occurs on the basis of primary heart diseases and may be combined with valve perforations. Cleft-like indentations (CLIs) were suggested by Ring et al. Read More

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http://dx.doi.org/10.1002/jcu.22697DOI Listing
January 2019
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