1,851 results match your criteria Missed Abortion


Retrospective analysis of prognostic value of the neutrophil-to-lymphocyte ratio in early miscarriages: A 8-year survey.

Authors:
Youngsun Kim

Medicine (Baltimore) 2020 Jul;99(27):e20888

This study aims to identify prognostic value of neutrophil-to-lymphocyte ratio (NLR) in early miscarriages. A total of 260 pregnant women with vaginal spotting were recruited from the Department of Obstetrics and Gynecology of the Kyung Hee Medical Center from January 1, 2011, and December 31, 2018. Venous samples were obtained from the women for measurements of platelet-to-lymphocyte ratio, lymphocyte-to-monocyte ratio, and NLR. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000020888DOI Listing

Can neutrophil-to-lymphocyte and monocyte-to-lymphocyte ratios be useful markers for predicting missed abortion in the first trimester of pregnancy?

J Obstet Gynaecol Res 2020 Jun 25. Epub 2020 Jun 25.

Department of Obstetrics and Gynecology, Qilu Hospital, Shandong University, Jinan, China.

Aim: To explore whether neutrophil-to-lymphocyte ratio (NLR) and monocyte-to-lymphocyte ratio (MLR) could predict missed abortion (MA) at 7-13 week's gestation.

Methods: A total of 363 women with a diagnosis of MA and 232 women with normal pregnancy at 7-13 week's gestation, who visited our hospital from June 2012 to May 2018 were retrospectively analyzed. At 7 week's gestation, total and differential leukocyte counts, NLR and MLR were compared between women with MA (n = 69) and normal controls (n = 53). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jog.14349DOI Listing

Cesarean Scar Ectopic Pregnancy: The Lurking Danger in Post Cesarean Failed Medical Abortion.

J Family Reprod Health 2019 Dec;13(4):223-227

Department of Obstetrics and Gynecology, AIIMS Patna, Patna, India.

Cesarean scar pregnancy (CSP) is a potentially life threatening ectopic pregnancy where a missed diagnosis is commoner than an accurate diagnosis. Incidence of Ectopic pregnancy is 1 - 2 % and cesarean scar ectopic occurs in about (0.05%) 1 in 2000 of all pregnancies. Read More

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264869PMC
December 2019

Platelet to Lymphocyte Ratio and Neutrophil to Lymphocyte Ratio in Missed Abortion.

Rev Bras Ginecol Obstet 2020 May 29;42(5):235-239. Epub 2020 May 29.

Private Balkan Hospital, Edirne, Turkey.

Objective:  Missed abortion occurs in ∼ 15% of all clinical pregnancies. The pathogenesis is not clearly known. However, defective placentation resulting in maternal systemic inflammatory response is considered responsible for missed abortion. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/s-0040-1709693DOI Listing

Excessive reactive oxygen species induce apoptosis via the APPL1-Nrf2/HO-1 antioxidant signalling pathway in trophoblasts with missed abortion.

Life Sci 2020 Aug 12;254:117781. Epub 2020 May 12.

Department of Gynecology, the Affiliated Hospital of Jiangsu University, Jiangsu University, Zhenjiang, Jiangsu 212001, China. Electronic address:

Aims: Previous evidence has demonstrated that oxidative stress is related to the pathogenesis of missed abortion (MA), but the specific mechanism remains obscure. The adaptor protein APPL1 is one of the differential proteins in chorionic trophoblasts. Thus, this study aimed to assess the potential influence of APPL1 on oxidative stress responses as well the possible molecular mechanisms involving in MA. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.lfs.2020.117781DOI Listing

Missed Abortion Presented with Worsening Hyperemesis Gravidarum.

Cureus 2020 Apr 1;12(4):e7499. Epub 2020 Apr 1.

Internal Medicine, Lincoln Medical Center, New York City, USA.

Hyperemesis gravidarum (HG) is the most common cause of in-patient hospitalizations during the first half of pregnancy. The etiology of HG has not yet been elucidated, and the treatment is mainly symptomatic. Untreated severe HG can lead to catastrophic maternal complications such as cardiac arrhythmia and death. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7759/cureus.7499DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195207PMC

Coronavirus disease 2019 in pregnant women: a report based on 116 cases.

Am J Obstet Gynecol 2020 07 23;223(1):111.e1-111.e14. Epub 2020 Apr 23.

Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing, China. Electronic address:

Background: The coronavirus disease 2019, caused by severe acute respiratory syndrome coronavirus 2, is a global public health emergency. Data on the effect of coronavirus disease 2019 in pregnancy are limited to small case series.

Objective: To evaluate the clinical characteristics and outcomes in pregnancy and the vertical transmission potential of severe acute respiratory syndrome coronavirus 2 infection. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajog.2020.04.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177142PMC

Pigment epithelium‑derived factor facilitates NLRP3 inflammasome activation through downregulating cytidine monophosphate kinase 2: A potential treatment strategy for missed abortion.

Int J Mol Med 2020 May 26;45(5):1436-1446. Epub 2020 Feb 26.

Department of Gynecology and Obstetrics, Changning Maternity and Infant Health Hospital, Shanghai 200050, P.R. China.

A number of conditions may underlie the occurrence of missed abortion (MA), including inflammation. Pigment epithelium‑derived factor (PEDF) is a novel mediator of the inflammation‑related nucleotide‑binding oligomerization domain‑like receptor protein 3 (NLRP3) inflammasome, which is associated with several human diseases. However, the association between MA and NLRP3 inflammasome, and whether PEDF is reduced in MA, remain unknown. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3892/ijmm.2020.4517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138263PMC
May 2020
1.880 Impact Factor

Twin pregnancies with uterine fibroids are not at increased risk for obstetric complications: single center cohort study.

BMC Pregnancy Childbirth 2020 Apr 15;20(1):222. Epub 2020 Apr 15.

Department of Obstetrics and Gynecology, CHA Gangnam Medical Center, CHA University, 566, Nonhyeon-ro, Gangnam-gu, Seoul, 135-081, Republic of Korea.

Background: Twin pregnancies with uterine fibroid(s) (UFs) may not be at increased risk for obstetric complications compared to those without UFs. However, there was no reported comparison study with obstetric outcomes and complications of twin pregnancy after myomectomy. We aimed to compare the pregnancy outcomes in twin pregnancies with or without uterine fibroid(s), and also compared in patients with previous myomectomy history in Korean women. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12884-020-02908-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161148PMC

Pregnancy loss: A 40-year nationwide assessment.

Acta Obstet Gynecol Scand 2020 Apr 7. Epub 2020 Apr 7.

Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.

Introduction: Pregnancy loss is frequent. We aimed to assess the frequency and trends in pregnancy losses according to female age and mode of conception over a 40-year follow-up period.

Material And Methods: In a national historical prospective cohort study, we followed all Danish women 10-49 years over the 40-year study period 1978-2017. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/aogs.13860DOI Listing

Assisted Reproductive Techniques and Pregnancy Results in Women with Mayer-Rokitansky-Küster-Hauser Syndrome Undergoing Uterus Transplantation: the Czech Experience.

J Pediatr Adolesc Gynecol 2020 Mar 26. Epub 2020 Mar 26.

Department of Obstetrics and Gynaecology, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.

Study Objective: This study aimed to evaluate the reproductive potential of patients with Mayer-Rokitansky-Küster-Hauser syndrome (MRKHS) who were candidates for uterus transplantation (UTx) before inclusion in the experimental trial, and to summarize the existing experience with posttransplantation embryo transfers in functionally successful cases.

Design And Setting: A prospective study at a tertiary medical center.

Participants: Ten pre-UTx women with MRKHS and 7 successful UTx cases. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jpag.2020.03.006DOI Listing

Talin1 regulates the endometrial epithelial cell adhesive capacity by interacting with LASP1 and Vitronectin.

Reprod Biol 2020 Jun 26;20(2):229-236. Epub 2020 Feb 26.

Department of Reproductive Center, First Affiliated Hospital ofGuangxi Medical University, Nanning, Guangxi, 530021, China. Electronic address:

The endometrium is a highly complex tissue that is vulnerable to subtle gene expression changes and is the first point of contact for an implanting blastocyst. Talin1 has previously been identified to regulate cytoskeleton and cell motility, however it has not been investigated in association with infertility. Herein, we presented that Talin1 dysregulation in the missed abortion endometrium would negatively influence endometrial adhesive capacity. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.repbio.2020.02.006DOI Listing

Biomarkers for placental disease in mares.

Theriogenology 2020 Jul 30;150:302-307. Epub 2020 Jan 30.

Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois Urbana-Champaign, Urbana, IL, 61802, USA.

Placentitis is an important cause of abortion, stillbirth, and neonatal death in horses. The diagnosis of placentitis is based on occurrence of clinical signs (premature mammary gland development and vulvar discharge) and ultrasonography of the caudal placental pole. However, early and subtle cases can be missed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.theriogenology.2020.01.073DOI Listing
July 2020
1.798 Impact Factor

A case of spontaneous heterotopic pregnancy in natural conception complicated with hemoperitoneum.

Heliyon 2020 Feb 10;6(2):e03373. Epub 2020 Feb 10.

Family Medicine Center, West Kendall Baptist Hospital, Baptist Health South Florida, Miami, FL, USA.

Heterotopic pregnancy, defined as simultaneous intrauterine and ectopic gestations, is an uncommon occurrence in women who conceive without assisted reproduction techniques. We present the case of 28 years old female with strong family history of multiple gestations, who presented with acute severe abdominal pain and diagnosed with spontaneous heterotopic pregnancy in natural conception. Ectopic pregnancy was successfully removed surgically to conserve the uterine pregnancy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.heliyon.2020.e03373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013160PMC
February 2020

miR-98 is involved in missed abortion by targeting GDF6 and FAPP2.

Reproduction 2020 05;159(5):525-537

Reproductive and Genetic Center of National Research Institute for Family Planning, Beijing, China.

Missed abortion (MA) is a common disease in obstetrics and gynecology. More and more studies have focused on the relationship between miRNAs and pregnancy maintenance and its related diseases. The aim of this article is to explore the relationship between miRNA and MA. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1530/REP-19-0282DOI Listing

Invasive endometrial adenocarcinoma and missed abortion: A case report.

Gynecol Oncol Rep 2020 Feb 21;31:100531. Epub 2019 Dec 21.

Division of Gynecologic Oncology, Department of Obstetrics & Gynecology, West Penn Hospital/Allegheny Health Network, United States.

Background: Endometrial cancer is the most common gynecologic cancer in the United States; however, reports of endometrial cancer diagnosed in the setting of intrauterine gestation are rare.

Case: We describe the case of a clinical stage IA grade 1 endometrioid endometrial adenocarcinoma diagnosed at the time of D&C performed for missed abortion in a gravida 1 para 0 female with no identifiable risk factors. Fertility-sparing treatment, with combined oral megestrol acetate and levonorgestrel intrauterine system, was used to manage this incidentally-diagnosed carcinoma with endometrial sampling every 3 months. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.gore.2019.100531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970154PMC
February 2020

Operative hysteroscopy-assisted pregnancy termination after failed surgical abortion in missed abortion of woman with complete septate uterus.

Obstet Gynecol Sci 2020 Jan 26;63(1):102-106. Epub 2019 Dec 26.

Department of Obstetrics and Gynecology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

First trimester surgical abortion is an effective and safe procedure. Although its failure is uncommon, congenital uterine anomaly may be considered as one of the etiologic factors in such cases. Here, we report a rare case of surgical abortion failure that was successfully managed by operative hysteroscopy-assisted dilatation and evacuation (D&E) under ultrasound guidance in a woman with complete uterine septum. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5468/ogs.2020.63.1.102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962582PMC
January 2020

Restoration of fertility in a woman with giant prolactinoma in response to cabergoline treatment.

Endocrinol Diabetes Metab Case Rep 2019 Sep 6;2019. Epub 2019 Sep 6.

Department of English Language for Natural FacultiesLomonosov Moscow State University, Moscow, Russian Federation.

Summary: A 32-year-old woman presented with primary amenorrhoea, prolactin (PRL) level of 154 150 mIU/L and was diagnosed with a giant pituitary adenoma measuring maximum 6.2 cm. Cabergoline (CAB) treatment at a dose of 0. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1530/EDM-19-0023DOI Listing
September 2019

Anti-D prophylaxis for rhesus D (RhD)-negative women having an abortion of a pregnancy up to 13 weeks' gestation: a systematic review and new NICE consensus guidelines.

BMJ Sex Reprod Health 2020 Jan 20. Epub 2020 Jan 20.

Department of Haematology, Imperial College Healthcare NHS Trust and NHS Blood & Transplant, London, UK.

Background: In order to develop the 2019 National Institute for Health and Care Excellence (NICE) national guideline on abortion care for the National Health Service1 we undertook a systematic review comparing anti-D prophylaxis to no prophylaxis in rhesus D (RhD)-negative women undergoing medical or surgical abortion of pregnancy at ≤13 weeks' gestation METHODS: We searched Embase, Medline and the Cochrane Library on 19 October 2018. We also consulted experts and checked reference lists for any missed trials. Eligible studies were randomised controlled trials and non-randomised comparative studies, published in English from 1985 onwards, comparing anti-D prophylaxis to no anti-D prophylaxis in RhD-negative women undergoing medical or surgical abortion at ≤13 weeks' gestation, and reporting subsequent anti-D isoimmunisation/sensitisation or subsequent affected pregnancy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bmjsrh-2019-200536DOI Listing
January 2020

Initiation of abortion before there is definitive ultrasound evidence of intrauterine pregnancy: A systematic review with meta-analyses.

Acta Obstet Gynecol Scand 2020 04 22;99(4):451-458. Epub 2020 Jan 22.

National Guideline Alliance, Royal College of Obstetricians and Gynaecologists, London, UK.

Introduction: Women are increasingly presenting for abortion at very early gestation. However, providers may be reluctant to conduct abortion at this stage as they may be concerned that they cannot exclude an ectopic pregnancy or that they may terminate a non-viable pregnancy, or may be concerned that both medical and surgical methods may be less effective at this stage of gestation. This provider concern may result in delays in the abortion as additional investigations may be required until an intrauterine pregnancy can be confirmed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/aogs.13797DOI Listing

Heterotopic Pregnancy - A Diagnostic Challenge. Six Case Reports and Literature Review.

Cureus 2019 Nov 5;11(11):e6080. Epub 2019 Nov 5.

Radiology, Hamad Medical Corporation, Doha, QAT.

Heterotopic pregnancy is defined as the simultaneous presence of intrauterine and ectopic pregnancies. It is a rare condition, but due to the increasing use of artificial reproductive techniques, the incidence of heterotopic pregnancy is increasing. Most of the patients with heterotopic pregnancy have a previous history of infertility or tubal diseases. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7759/cureus.6080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894893PMC
November 2019

Efficacy of mifepristone and misoprostol for medical treatment of missed miscarriage in clinical practice-A cohort study.

Acta Obstet Gynecol Scand 2020 04 22;99(4):488-493. Epub 2019 Dec 22.

Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden.

Introduction: It has been estimated that one out of every four women experience first-trimester miscarriage. Missed miscarriage is a common form of early miscarriage where the products of conception are not expelled from the uterus. It is diagnosed by ultrasound. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/aogs.13780DOI Listing

Mifepristone and misoprostol versus misoprostol alone for uterine evacuation after early pregnancy failure: study protocol for a randomized double blinded placebo-controlled comparison (Triple M Trial).

BMC Pregnancy Childbirth 2019 Nov 27;19(1):443. Epub 2019 Nov 27.

Department of Obstetrics and Gynaecology, Radboud University Medical Centre, Geert Grooteplein Zuid 10, Nijmegen, GA, 6525, The Netherlands.

Background: Early pregnancy failure (EPF) is a common complication of pregnancy. If women do not abort spontaneously, they will undergo medical or surgical treatment in order to remove the products of conception from the uterus. Curettage, although highly effective, is associated with a risk of complications; medical treatment with misoprostol is a safe and less expensive alternative. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12884-019-2497-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6880504PMC
November 2019

Trends in the incidence, rate and treatment of miscarriage-nationwide register-study in Finland, 1998-2016.

Hum Reprod 2019 11;34(11):2120-2128

Department of Obstetrics and Gynaecology, Oulu University Hospital, 90220, Oulu, Finland.

Study Question: What changes have occurred in the incidence of miscarriage, its treatment options, and the profile of the women having miscarriages in Finland between 1998 and 2016?

Summary Answer: The annual incidence of registry-identified miscarriage has declined significantly between 1998 and 2016, and non-surgical management has become the dominant treatment.

What Is Known Already: Miscarriage occurs in 8-15% of clinically recognized pregnancies and in ~30% of all pregnancies. Increasing maternal age is associated with an increasing risk of miscarriage. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/humrep/dez211DOI Listing
November 2019

Follow-up strategies to confirm the success of medical abortion of pregnancies up to 10 weeks' gestation: a systematic review with meta-analyses.

Am J Obstet Gynecol 2020 06 9;222(6):551-563.e13. Epub 2019 Nov 9.

National Guideline Alliance, Royal College of Obstetricians and Gynaecologists, London, UK.

Objective: To compare the effectiveness, safety, and acceptability of in-clinic and remote/self-assessment, as well as different remote/self-assessments, for confirming the success of medical abortion at ≤10 weeks' gestation.

Data Sources: Ovid Embase Classic and Embase; Ovid MEDLINE(R) and Epub Ahead-of-Print, In-Process & Other Non-Indexed Citations and Daily; and the Cochrane Library. We also consulted experts in this field for any ongoing or missed trials. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajog.2019.11.1244DOI Listing

[Identification of cryptic structural chromosomal aberrations in parents through detection of copy number variations in miscarriage tissues].

Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2019 Nov;36(11):1123-1126

Shenyang Women and Children's Hospital, Shenyang, Liaoning 110011, China.

Objective: To explore the genetic cause for abnormal pregnancies through detecting chromosomal copy number variations (CNVs) in abortic tissues by next generation sequencing (NGS).

Methods: NGS technique was used to detect CNVs in abortion tissues. Parental chromosomal karyotypes were predicted based on the results. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3760/cma.j.issn.1003-9406.2019.11.017DOI Listing
November 2019

Comprehensive analysis of the differential expression profile of microRNAs in missed abortion.

Kaohsiung J Med Sci 2020 Feb 5;36(2):114-121. Epub 2019 Nov 5.

Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, P.R. China.

To screen the key circulating microRNAs (miRNAs) involved in missed abortion (MA) and explore their role in MA process. We examined the miRNA profile from the serum of three MA patients and three early pregnancy induced abortion patients (controls) by next-generation sequencing. We analyzed the target genes of the differentially expressed (DE) miRNAs to analyze the function and pathway enrichment using Gene Ontology and Kyoto Encyclopedia of Genes and Genomes, respectively. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/kjm2.12144DOI Listing
February 2020

Acute pelvic pain following miscarriage heterotopic pregnancy must be excluded: case report.

BMC Emerg Med 2019 10 25;19(1):59. Epub 2019 Oct 25.

Bendigo Health, Bendigo, Victoria, Australia.

Background: Heterotopic pregnancies are increasing in prevalence and this case highlights the importance of excluding the diagnosis in patients with pelvic pain following miscarriage. A known pre-existing intrauterine pregnancy can be falsely reassuring and delay the diagnosis of a potentially life-threatening concurrent ectopic pregnancy.

Case Presentation: In this report, we describe a case of spontaneous heterotopic pregnancy in a woman who had initially presented with pelvic pain and vaginal bleeding, and was diagnosed on pelvic ultrasound with a missed miscarriage; a non-viable intrauterine pregnancy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12873-019-0268-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814984PMC
October 2019

A case report of pelviscopic resection of invasive hydatidiform mole.

Medicine (Baltimore) 2019 Oct;98(41):e17565

Obstetrics and Gynecology, Soonchunhyang University College of Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Republic of Korea.

Rationale: Invasive moles occur in the fertile period, with about 95% occurring after previous mole removal and the remaining 5% occurring after several other pregnancies.

Patient Concerns: A 27-year-old patient developed a rare invasive mole two months after a missed abortion.

Diagnoses: A transvaginal ultrasound scan revealed a 3. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000017565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6799454PMC
October 2019
1 Read

The association between vaginal bacterial composition and miscarriage: a nested case-control study.

BJOG 2020 01 31;127(2):264-274. Epub 2019 Oct 31.

Tommy's National Centre for Miscarriage Research, Imperial College London, London, UK.

Objective: To characterise vaginal bacterial composition in early pregnancy and investigate its relationship with first and second trimester miscarriages.

Design: Nested case-control study.

Setting: Queen Charlotte's and Chelsea Hospital, Imperial College Healthcare NHS Trust, London. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/1471-0528.15972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6972675PMC
January 2020
1 Read

Expression of vitamin D and vitamin D receptor in chorionic villous in missed abortion.

Gynecol Endocrinol 2019 ;35(sup1):49-55

The Research Institute of Obstetrics, Gynecology and Reproductology Named after D.O. Ott , St. Petersburg , Russia.

The contemporary world despite its enough developed medicine and generally highly enlightened population faces a great problem of vitamin, micro-element and nutrient deficiency turning to become the XXI century pandemic. Along with that significant growth of interest can be seen towards vitamin D importance for reproductive physiology. The fact is that vitamin D receptors (VDR) have been detected in women's ovarium tissue, fallopian tubes, decidua and placenta. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/09513590.2019.1653563DOI Listing
March 2020
3 Reads

Alpha fetoprotein (AFP) participates in the build up of hematopoietic cells in the early embryonic stage: an abortion case observation.

Diagn Pathol 2019 Aug 1;14(1):85. Epub 2019 Aug 1.

School of Medicine, South China University of Technology, Guangzhou Higher Education Mega Center, Guangzhou, 510006, Guangdong, China.

Background: At the 3rd week of human embryo, some cell clumps are formed by the hyperplasia of mesenchymal cells at the germ layer of the yolk sac wall. These cell clumps are known as blood islands. The cells in the center of the blood islands further develop into primitive blood cells, such as hematopoietic stem cells. Read More

View Article

Download full-text PDF

Source
https://diagnosticpathology.biomedcentral.com/articles/10.11
Publisher Site
http://dx.doi.org/10.1186/s13000-019-0858-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6670229PMC
August 2019
3 Reads

Complications and reproductive outcome after uterine artery embolization for retained products of conception.

J Obstet Gynaecol Res 2019 Oct 23;45(10):2007-2014. Epub 2019 Jul 23.

Department of Obstetrics and Gynecology, Hamanomachi Hospital, Fukuoka, Japan.

Aim: The purpose of this study was to evaluate the complications and reproductive outcome after uterine artery embolization (UAE) for retained products of conception (RPOC).

Methods: This was a retrospective medical-records review study of 57 women treated for RPOC. Participants were divided into two groups: women who underwent treatment with UAE (UAE group: n = 32, 56. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jog.14067DOI Listing
October 2019
4 Reads

Gynaecology problems in puberty.

Authors:
Sonia R Grover

Best Pract Res Clin Endocrinol Metab 2019 06 14;33(3):101286. Epub 2019 Jun 14.

Department of Paediatric and Adolescent Gynaecology, Royal Children's Hospital, 50 Flemington Rd, Parkville 3052, Australia. Electronic address:

With the onset of puberty a range of problems may be encountered by the young girl. Some of these include a range of gynaecological issues relating to delayed onset of puberty, delayed menarche, atypical pubertal changes and the identification of anomalies of the genital tract. The distinction between physiological events and pathological problems is important to avoid unnecessary distress and anxiety. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.beem.2019.06.002DOI Listing
June 2019
3 Reads

Comparison of the diagnostic value of histopathological examinations of miscarriage products after pharmacological induction of miscarriage and curettage.

Ginekol Pol 2019 ;90(6):331-335

Department of Anatomy, Morphology and Human Embryology, Wroclaw Medical University, Wroclaw, Poland.

Objectives: For early miscarriage (pregnancy loss ≤ 12 weeks of gestation), two types of therapeutic treatment are offered (pharmacotherapy and curettage of the uterine cavity) depending on the presence and severity of clinical symptoms as well as patient choice. Our study aimed to assess the diagnostic value of the results of histopathological examinations of miscarriage products in relation to the administered treatments.

Material And Methods: 850 medical records from patients diagnosed with missed miscarriage or empty gestational sac were analyzed retrospectively. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5603/GP.2019.0061DOI Listing
March 2020
2 Reads

Pregnancy Prevention on the Fly: An Exploratory Study of Contraceptive Lapse Among Young Women Traveling Internationally.

J Womens Health (Larchmt) 2019 07 10;28(7):951-960. Epub 2019 Jun 10.

Division of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis, Minnesota.

International travel is increasingly popular, and women comprise half of all outbound travel from the United States (almost 46 million trips in 2017). The implications of international travel for women's reproductive health are not fully clear due to lack of data on travelers' contraceptive use. Women attending a U. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/jwh.2018.7371DOI Listing
July 2019
4 Reads

Mast cell involvement in human cervical ripening.

Eur J Obstet Gynecol Reprod Biol 2019 Jul 16;238:157-163. Epub 2019 May 16.

Institution of Clinical Sciences, Department of Obstetrics and Gynaecology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. Electronic address:

Objective: Cervical ripening resembles an inflammatory process in many aspects, involving invasion of inflammatory cells, collagen breakdown and remodelling of the extracellular matrix. Mast cells produce a variety of inflammatory agents and are attributed a functional role in cervical ripening. The aim of this study was to examine if cervical mast cells are increased in number and stimulated during pregnancy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejogrb.2019.05.010DOI Listing
July 2019
21 Reads

Prenatal diagnosis of 17q12 microdeletion and microduplication syndrome in fetuses with congenital renal abnormalities.

Mol Cytogenet 2019 17;12:19. Epub 2019 May 17.

Department of Obstetrics and Gynecology, The First Affiliated Hospital Of AFMU (Air Force Medical University), 127 ChangLe West Road, Xi'an, 710032 Shaanxi China.

Background: Copy number variations (CNVs) involving the 17q12 region are associated with a broad range of clinical phenotypes. Deletion of the 17q12 chromosome results in structural or functional abnormalities in the kidney and urethra, type 5 diabetes (MODY5), and neurodevelopmental or neuropsychiatric disorders. Microduplication of 17q12 is rare and is associated with an increased risk of epilepsy and mental retardation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13039-019-0431-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525371PMC
May 2019
6 Reads

Diagnostic assessment of foetal brain malformations with intra-uterine MRI versus perinatal post-mortem MRI.

Neuroradiology 2019 Aug 10;61(8):921-934. Epub 2019 May 10.

Department of Radiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, WC1N 3JH, UK.

Purpose: To evaluate differences in diagnostic yield of intra-uterine foetal (iuMR) and post-mortem MRI (PMMR) for complex brain malformations, using autopsy as the reference standard.

Methods: In this retrospective, multicentre study spanning 2 years, we reviewed 13 terminated singleton pregnancies with a prenatal ultrasound finding of complex foetal cerebral abnormalities, referred for both iuMR and PMMR. The iuMR and PMMR studies of the brain were reported independently by two groups of radiologists, blinded to each other's reports. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00234-019-02218-9
Publisher Site
http://dx.doi.org/10.1007/s00234-019-02218-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620257PMC
August 2019
5 Reads

[Successful pregnancy and delivery achieved with eculizumab administration initiated after a preceding missed abortion in a patient with paroxysmal nocturnal hemoglobinuria].

Rinsho Ketsueki 2019 ;60(4):281-285

Division of Hematology, Department of Medicine, Juntendo University School of Medicine.

Pregnancy with paroxysmal nocturnal hemoglobinuria (PNH) poses a high risk of thrombosis, maternal death, miscarriage, and premature infants. Eculizumab lowers complications for pregnancy with PNH. A proposed protocol for the management of pregnancy in women with PNH by The National Research Group on Idiopathic Bone Marrow Failure Syndrome (the Japanese Guideline) recommends patients to start eculizumab at an early stage of pregnancy if they have not been treated with eculizumab or continue eculizumab during pregnancy. Read More

View Article

Download full-text PDF

Source
https://www.jstage.jst.go.jp/article/rinketsu/60/4/60_281/_a
Publisher Site
http://dx.doi.org/10.11406/rinketsu.60.281DOI Listing
August 2019
8 Reads

Clinical pregnancy after deceased donor uterus transplantation: Lessons learned and future perspectives.

J Obstet Gynaecol Res 2019 Aug 6;45(8):1458-1465. Epub 2019 May 6.

Department of Obstetrics and Gynecology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic.

Aim: To describe our first clinical pregnancy following a uterus transplant from a brain-dead donor and to discuss current issues with deceased donor uterus transplantation as they relate to obstetrical success.

Methods: In August 2016, a 26-year-old woman with Mayer-Rokitansky-Küster-Hauser syndrome was the fourth person worldwide to receive a uterine transplant from a deceased donor and was the second in our trial. in vitro fertilization treatments using the long gonadotropin-releasing hormone agonist protocol preceded the transplantation procedure. Read More

View Article

Download full-text PDF

Source
https://onlinelibrary.wiley.com/doi/abs/10.1111/jog.13992
Publisher Site
http://dx.doi.org/10.1111/jog.13992DOI Listing
August 2019
11 Reads

Comparison of Effectiveness and Patient Satisfaction of Vaginal Versus Oral Misoprostol in Treatment of Missed Miscarriage.

Open Access Maced J Med Sci 2019 Mar 26;7(6):955-958. Epub 2019 Mar 26.

RR College of Pharmacy, Chikkabanavara, Bangalore, India.

Background: In recent years' medical management with misoprostol is an effective alternative to surgical evacuation. But there is a dearth of evidence to reveal the effectiveness of the different routes of misoprostol and satisfaction rate among the patients treated with these routes.

Aim: This study was conducted to compare the effectiveness and patient's satisfaction rate of vaginal versus oral misoprostol. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3889/oamjms.2019.192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454167PMC
March 2019
2 Reads

Paternal uniparental isodisomy of tyrosine hydroxylase locus at chromosome 11p15.4: spectrum of phenotypical presentations simulating hydatidiform moles.

Mod Pathol 2019 07 5;32(8):1180-1188. Epub 2019 Apr 5.

Department of Pathology, Yale University School of Medicine, New Haven, CT, USA.

Uniparental disomy is an abnormal genetic condition in which both homologous chromosomes or part of the chromosome are inherited from one parent and the other parent's homologous chromosome is lost. We report three cases of gestations with paternal uniparental isodisomy at tyrosine hydroxylase or TH01 locus on chromosome 11p15.4 identified by DNA genotyping. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41379-019-0266-0DOI Listing
July 2019
10 Reads

Increased Fetal Chromosome Detection with the Use of Operative Hysteroscopy During Evacuation of Products of Conception for Diagnosed Miscarriage.

J Minim Invasive Gynecol 2020 01 26;27(1):160-165. Epub 2019 Mar 26.

Advanced Gynecologic Surgery Institute, Chicago, Illinois (Drs. Cholkeri-Singh and Miller).

Study Objective: To determine whether incorporation of operative hysteroscopy with biopsy of products of conception, in conjunction with a suction curettage for a first trimester missed abortion, affected the rate of maternal cell contamination when chromosomal analysis was performed on the products of conception, and to determine the rates of retained products of conception with incorporation of hysteroscopy after suction curettage.

Design: Retrospective chart study.

Setting: Private, minimally invasive surgery and infertility practice with academic-community hospital affiliation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmig.2019.03.014DOI Listing
January 2020
18 Reads

Medical management of first trimester missed miscarriage: the efficacy and complication rate.

J Obstet Gynaecol 2019 Jul 27;39(5):647-651. Epub 2019 Mar 27.

b Department of Reproductive Medicine and Gynaecological Endocrinology, Clinic for Gynaecology and Perinatology , University Medical Centre Maribor , Maribor , Slovenia.

Our aim of the study was to evaluate the efficacy and complication rate of our inpatient medical management protocol for missed miscarriages. Three-hundred and ninety women hospitalised at our tertiary centre because of a missed miscarriage/anembryonic pregnancy in 2012-2013 were included in this retrospective study. The women underwent either a low (until 9 + 0 weeks of gestation) or high gestational age (from 9 + 1 until 15 + 6 weeks of gestation) management protocol. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01443615.2018.1535577DOI Listing
July 2019
8 Reads

Expression of galectin-3 and apoptosis in placental villi from patients with missed abortion during early pregnancy.

Exp Ther Med 2019 Apr 31;17(4):2623-2631. Epub 2019 Jan 31.

Department of Pediatrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong 510889, P.R. China.

The success of a pregnancy relies on moderate trophoblast apoptosis. If the 'inhibition-induction' balance of apoptosis is broken, a pathological pregnancy may occur. Galectin-3 has an important role in numerous biological processes, including tumor cell apoptosis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3892/etm.2019.7227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425259PMC
April 2019
11 Reads

Placenta Increta Presenting as Retained Placenta: A Report of 3 Cases.

Fetal Pediatr Pathol 2019 Jun 19;38(3):215-225. Epub 2019 Mar 19.

b Pathology & Laboratory Medicine , Rutgers-New Jersey Medical School , Newark , NJ , USA.

Objectives: Morbid adherence is a risk factor for retained placenta (RP). We encountered three cases of placenta increta presenting clinically as delayed postpartum hemorrhage.

Methods: This was a retrospective study of three cases of placenta increta presenting as RP. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/15513815.2019.1582121DOI Listing
June 2019
9 Reads