100,020 results match your criteria Minimally invasive surgery[Journal]


Dissolvable microneedle patch containing doxorubicin and docetaxel is effective in 4T1 xenografted breast cancer mouse model.

Int J Pharm 2018 Dec 14. Epub 2018 Dec 14.

Department of Pharmacy, Birla Institute of Technology and Science (BITS) Pilani, Hyderabad Campus, Hyderabad 500078, Telangana, India. Electronic address:

Microneedle-devices provide a promising alternative to syringe-injection-based administration of chemotherapeutics. Dissolvable polymeric microneedles provide possibility of carrying greater payload and dual drugs. Here, we report development of polyvinyl pyrrolidone and polyvinyl alcohol composite dissolvable polymeric microneedle system for co-delivery of doxorubicin HCl and docetaxel. Read More

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December 2018
1 Read

Safety of robotic-assisted gynecologic surgery and early hospital discharge in elderly patients.

Am J Obstet Gynecol 2018 Dec 14. Epub 2018 Dec 14.

New York University Langone Medical Center. Electronic address:

Background: A minimally invasive surgical approach has proven to decrease peri- and post-operative complications and shorten duration of hospital stay, however there is limited data evaluating the safety of robotic-assisted surgery and early hospital discharge in the elderly population. As age is a well-known, independent risk factor for peri-operative morbidity and gynecologists treat many elderly patients, this is an important area of study.

Objective: To evaluate discharge timing and surgical outcomes in elderly compared to younger patients undergoing robotic-assisted gynecologic surgery. Read More

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December 2018
1 Read

Use of C-reactive protein for the early prediction of anastomotic leak after esophagectomy: Systematic review and Bayesian meta-analysis.

PLoS One 2018 17;13(12):e0209272. Epub 2018 Dec 17.

Department of Biomedical Sciences for Health, Division of General Surgery, University of Milan, IRCCS Policlinico San Donato, Milan, Italy.

Background: Early suspicion, diagnosis, and timely treatment of anastomotic leak after esophagectomy is essential. Retrospective studies have investigated the role of C-reactive protein (CRP) as early marker of anastomotic leakage. The aim of this systematic review and meta-analysis was to evaluate the predictive value of CRP after esophageal resection. Read More

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December 2018

CT-guided minimally-invasive penile fracture repair.

Int Braz J Urol 2018 Dec 15;44. Epub 2018 Dec 15.

Department of Traditional Chinese Medicine, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China.

We present the case of a 28 year old patient with an incomplete tear of the tunica albuginea occurred after having sexual intercourse in the female superior position. The diagnostic assessment was performed first clinically, then with CT, owing to its high resolution, allowed to exactly detect the tear location leading to precise preoperative planning. After adequate diagnosis through imaging and proper planning, the patient was performed a selective minimally invasive surgical approach to repair the lesion. Read More

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December 2018

Geometric Calibration of Markerless Optical Surgical Navigation System.

Int J Med Robot 2018 Dec 17:e1978. Epub 2018 Dec 17.

Department of Cardiac Surgery, Guangdong Cardiovascular Institute, Guangdong General Hospital, uangdong Academy of Medical Science, Guangzhou, China.

Background: Patient-to-image registration is required for image-guided surgical navigation, but marker-based registration is time consuming and subject to manual error. Markerless registration is an alternative solution to avoid these issues.

Methods: This study designs a calibration board and proposes a geometric calibration method to calibrate the near infrared tracking and structured light components of the proposed optical surgical navigation system simultaneously. Read More

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December 2018

Robot-Assisted Repair of E Biliary Ductal Injury with Roux-en-Y Hepaticojejunostomy.

J Laparoendosc Adv Surg Tech A 2018 Dec 14. Epub 2018 Dec 14.

Department of Surgery, Rutgers, New Jersey Medical School , Newark, New Jersey.

Background: Common bile duct (CBD) injury is a serious complication of laparoscopic and open cholecystectomy. Early identification and minimally invasive repair, when possible, can prevent much of the morbidity associated with this injury.

Materials And Methods: A 36-year-old woman referred in the immediate perioperative period for CBD injury at the time of laparoscopic cholecystectomy. Read More

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December 2018

Addressing technical barriers for reliable, safe removal of fluoride from drinking water using minimally processed bauxite ores.

Dev Eng 2018 ;3:175-187

Energy Technology Area, Lawrence Berkeley National Laboratory, Berkeley, 94720 CA, USA.

Throughout the developing world, over 200 million people drink groundwater containing fluoride concentrations surpassing the World Health Organization's maximum recommended contaminant level (WHO-MCL) of 1.5 mg F/L, resulting in adverse health effects ranging from mottled tooth enamel to debilitating skeletal fluorosis. Existing technologies to remove fluoride from water, such as reverse osmosis and filtration with activated alumina, are expensive and are not accessible for low-income communities. Read More

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January 2018

Minimally Invasive Total Hip Arthroplasty in a Patient with Hereditary Multiple Exostoses: A Case Report.

Malays Orthop J 2018 Nov;12(3):53-56

Center for Joint Disease, Chonnam National University Hwasun Hospital, Jeonnam, Republic of Korea.

Hip geometry abnormalities found in patients with hereditary multiple exostoses (HME) could promote premature hip joint degeneration which needs treatment. We report the case of a 45-year old male with right hip arthrosis who underwent two-incision minimally invasive (MIS-2) total hip arthroplasty (THA), with satisfactory outcome. This technique could be an alternative approach for performing THA in patients with hereditary multiple exostoses. Read More

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November 2018

Minimally Invasive Osteosynthesis of Distal Tibia Fractures using Anterolateral Locking Plate.

Authors:
P Choudhari D Padia

Malays Orthop J 2018 Nov;12(3):38-42

Department of Orthopaedics, Sri Aurobindo Medical College and Post Graduate Institute, Indore, India.

Plating in distal tibia fractures are associated with higher rate of soft tissue complications. As adequate soft tissue cover is available over anterolateral surface of the tibia, use of anterolateral plate fixation in distal tibia fractures has increased. The purpose of our research is to evaluate the outcomes of anterolateral locking plate fixation in distal tibia fractures using ORIF. Read More

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November 2018
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Risk of Axillary Nerve Injury in Standard Anterolateral Approach of Shoulder: Cadaveric Study.

Malays Orthop J 2018 Nov;12(3):1-5

Department of Orthopaedics, Lerdsin General Hospital, Bangkok, Thailand.

The anterolateral acromion approach of the shoulder is popular for minimally invasive plate osteosynthesis (MIPO) technique. However, there are literatures describing the specific risks of injury of the axillary nerve using this approach. Nevertheless, most of the studies were done with Caucasian cadavers. Read More

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November 2018

Assessment of Detoxification Efficacy of Irradiation on Zearalenone Mycotoxin in Various Fruit Juices by Response Surface Methodology and Elucidation of Its Toxicity.

Front Microbiol 2018 30;9:2937. Epub 2018 Nov 30.

Toxicology and Immunology Division, DRDO-BU-Centre for Life Sciences, Bharathiar University, Coimbatore, India.

Fruits are vital portion of healthy diet owed to rich source of vitamins, minerals, and dietary fibers, which are highly favorable in keeping individual fit. Unfortunately, these days, one-third of fruits were infested with fungi and their toxic metabolites called mycotoxins, which is most annoying and pose significant health risk. Therefore, there is a need to suggest appropriate mitigation strategies to overcome the mycotoxins contamination in fruits. Read More

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November 2018

Functional Connectivity of Anterior Insula Predicts Recovery of Patients With Disorders of Consciousness.

Front Neurol 2018 30;9:1024. Epub 2018 Nov 30.

Department of Neurology and Brain Medical Centre, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.

We hypothesize that the anterior insula is important for maintenance of awareness. Here, we explored the functional connectivity alterations of the anterior insula with changes in the consciousness level or over time in patients with disorders of consciousness (DOC) and determined potential correlation with clinical outcomes. We examined 20 participants (9 patients with DOC and 11 healthy controls). Read More

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November 2018

Miniaturized Robotic End-Effector with Piezoelectric Actuation and Fiber Optic Sensing for Minimally Invasive Cardiac Procedures.

IEEE Sens J 2018 Jun 20;18(12):4961-4968. Epub 2018 Apr 20.

Department of Mechanical and Aerospace Engineering and Institute of Advanced Machines and Design, Seoul National University, Seoul, 08826, Korea and also with the Robotics Institute, Carnegie Mellon University, Pittsburgh, PA 15213, USA.

Each year 35,000 cardiac ablation procedures are performed to treat atrial fibrillation through the use of catheter systems. The success rate of this treatment is highly dependent on the force which the catheter applies on the heart wall. If the magnitude of the applied force is much higher than a certain threshold the tissue perforates, whereas if the force is lower than this threshold the lesion size may be too large and is inconsistent. Read More

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Outcomes Among Patients With Heart Failure With Reduced Ejection Fraction Undergoing Transcatheter Aortic Valve Replacement: Minimally Invasive Strategy Versus Conventional Strategy.

J Invasive Cardiol 2018 Dec 15. Epub 2018 Dec 15.

University Hospitals Cleveland Medical Center, 11100 Euclid Ave, Mailstop LKS 5038, Cleveland, OH 44106 USA.

Objectives: To investigate the effect of TAVR technique on in-hospital and 30-day outcomes in patients with aortic stenosis (AS) and reduced ejection fraction (EF).

Background: Patients with AS and concomitant low EF may be at risk for adverse hemodynamic effects from general anesthesia utilized in transcatheter aortic valve replacement (TAVR) via the conventional strategy (CS). These patients may be better suited for the minimally invasive strategy (MIS), which employs conscious sedation. Read More

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December 2018

Clinical outcomes of primary arterial embolization in severe hepatic trauma: A systematic review.

Diagn Interv Imaging 2018 Dec 13. Epub 2018 Dec 13.

General, Emergency and Robotic Surgery Unit, San Francesco Hospital, 08100 Nuoro NU, Italy.

Purpose: This purpose of this systematic review was to determine the safety and efficacy of arterial embolization as the primary treatment for grade III-V liver trauma, excluding the postoperative use of arterial embolization.

Material And Methods: A total of 24 studies published between January 2000 and June 2018 qualified for inclusion in this study. Four of them were prospective studies and 20 were retrospective. Read More

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December 2018

Arthroscopic techniques for treating ilio-psoas tendinopathy after hip arthroplasty.

Authors:
Olivier May

Orthop Traumatol Surg Res 2018 Dec 13. Epub 2018 Dec 13.

Médipôle Garonne, 45, rue de Gironis, 31300 Toulouse, France. Electronic address:

Impingement of hip arthroplasty components on soft tissues may adversely affect outcomes. An example is impingement of the cup on the ilio-psoas tendon, which has been reported in 0.4% to 8. Read More

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December 2018

A wide-margin liver resection improves long-term outcomes for patients with HBV-related hepatocellular carcinoma with microvascular invasion.

Surgery 2018 Dec 13. Epub 2018 Dec 13.

Department of Hepatic Surgery IV, the Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China. Electronic address:

Background: The impact of the resection margin on survival outcomes in patients with hepatocellular carcinoma remains to be determined. This study aimed to examine the association between the width of resection margin and the presence of microvascular invasion in hepatitis B virus-related hepatocellular carcinoma.

Methods: We reviewed data on 2,508 consecutive patients who underwent liver resection for a solitary, hepatitis B virus-related hepatocellular carcinoma for operative morbidity, tumor recurrence, and overall survival. Read More

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December 2018

Sialorrhea & aspiration control - A minimally invasive strategy uncomplicated by anticholinergic drug tolerance or tachyphylaxis.

Authors:
Joseph E Dohar

Int J Pediatr Otorhinolaryngol 2019 Jan 24;116:97-101. Epub 2018 Oct 24.

Voice Resonance and Swallowing Center UPMC Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, University of Pittsburgh School of Health & Rehabilitation, 4401 Penn Ave., Pittsburgh, PA, 15224, United States. Electronic address:

Objective: Sialorrhea complicated by aspiration is a primary source of morbidity and mortality in neurologically impaired children. Anticholinergics are an effective treatment option, but have traditionally been considered only adjuncts due to tachyphylaxis and drug tolerance. Similarly, Botox-A salivary gland injections are also considered adjunctive due to the need to repeat treatment every 3 months. Read More

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January 2019

Subconjunctival draining minimally-invasive glaucoma devices for medically uncontrolled glaucoma.

Cochrane Database Syst Rev 2018 Dec 16;12:CD012742. Epub 2018 Dec 16.

Ophthalmology, Nottingham University Hospital, Derby Road, Nottingham, UK, NG7 2UH.

Background: Glaucoma is a leading cause of irreversible blindness. Subconjunctival draining minimally-invasive glaucoma devices such as the Xen gelatin implant and InnFocus stent have been introduced as a treatment to prevent glaucoma progressing.These implants provide a channel to allow aqueous humour from the anterior chamber of the eye to drain into the subconjunctival space on the surface of the eye thus reducing intraocular pressure (IOP) and mimicking the mechanism of the most commonly undertaken glaucoma surgery, trabeculectomy. Read More

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December 2018
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The role of robotic aortic lymphadenectomy in gynecological cancer: surgical and oncological outcome in a single institution experience.

J Surg Oncol 2018 Dec 16. Epub 2018 Dec 16.

Division of Gynecologic Oncology, Department of Women's and Children's Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.

Background And Objective: This study aims to investigate the surgical outcomes observed in robotic transperitoneal aortic lymphadenectomy (AL) in gynecological cancer patients.

Methods: Retrospective data were collected and analyzed on 71 patients undergoing robotic surgical procedures for gynecological cancers, including transperitoneal AL, between December 2014 and February 2018 at the Catholic University of the Sacred Heart, Rome, Italy.

Results: Median age of the sample population was 50 years (range, 26-76 years). Read More

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December 2018

A Multi-Model Framework to Estimate Perfusion Parameters Using Contrast-Enhanced Ultrasound Imaging.

Med Phys 2018 Dec 16. Epub 2018 Dec 16.

Department of Radiology, Stanford University School of Medicine, Stanford, CA, 94305, USA.

Purpose: Contrast-enhanced ultrasound imaging (CEUS) has expanded the diagnostic potential of ultrasound by enabling real-time imaging and quantification of tissue perfusion. Several perfusion models and curve fitting methods have been developed to quantify the temporal behavior of tracer signal and standardize perfusion quantification. While the least-squares approach has traditionally been applied for curve-fitting, it can be inadequate for noisy and complex data. Read More

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December 2018

Influence of patient-specific anatomy on medical computed tomography and risk evaluation of minimally invasive surgery at the otobasis.

Eur Arch Otorhinolaryngol 2018 Dec 15. Epub 2018 Dec 15.

Department of Otorhinolaryngology, University Hospital Duesseldorf, Duesseldorf, Germany.

Purpose: With the increasing use of new minimally invasive approaches in temporal bone surgery, the need arises for evaluation of the risk of injury to sensitive anatomical structures. The factors that influence the measurement uncertainty (variation in representation of position and shape of anatomical structures) of imaging are of relevance. We investigate the effect of patients' anatomy on the measurement uncertainty of medical CT. Read More

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December 2018

Consensus Statement of the Italian Society of Colorectal Surgery (SICCR): management and treatment of complete rectal prolapse.

Tech Coloproctol 2018 Dec 15. Epub 2018 Dec 15.

Department of Colorectal Surgery, Santa Rita Clinic, Vercelli, Italy.

Rectal prolapse, rectal procidentia, "complete" prolapse or "third-degree" prolapse is the full-thickness prolapse of the rectal wall through the anal canal and has a significant impact on quality of life. The incidence of rectal prolapse has been estimated to be approximately 2.5 per 100,000 inhabitants with a clear predominance among elderly women. Read More

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December 2018
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Minimally Invasive Function-Preserving Gastrectomy with Sentinel Node Biopsy for Early Gastric Cancer.

Digestion 2018 Dec 14;99(1):14-20. Epub 2018 Dec 14.

Department of Surgery, Keio University School of Medicine, Tokyo, Japan.

Background: Recently, minimally invasive approaches such as endoscopic treatment or laparoscopic gastrectomy for early gastric cancer have made rapid progress. However, the extent of gastrectomy and lymphadenectomy in laparoscopic surgery is radical, similar to that of open gastrectomy for patients with early gastric cancer diagnosed as not indicated for endoscopic treatment. Since it is well known that lymph node metastasis is an important prognostic factor, the standard procedure of gastrectomy with radical lymph node dissection has been performed for the purpose of curative resection. Read More

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December 2018
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Current Status and Challenges of Endoscopic Treatments for Duodenal Tumors.

Digestion 2018 Dec 14;99(1):21-26. Epub 2018 Dec 14.

Division of Research and Development for Minimally Invasive Treatment, Cancer Center, Keio University School of Medicine, Tokyo,

Background: Superficial tumors of the duodenum, other than ampullary tumors, have been traditionally considered rare. However, reports of this kind of tumor have increased in recent times, and the demand for minimally invasive treatments have also increasing.

Summary: Adenomas and intramucosal carcinomas are target lesions for treatment. Read More

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December 2018

Endoscopic Submucosal Dissection in Patients with Ulcerative Colitis.

Digestion 2018 Dec 14;99(1):27-32. Epub 2018 Dec 14.

Department of Gastroenterology, National Hospital Organization Tokyo Medical Center, Tokyo,

Patients with ulcerative colitis have an increased risk of developing colorectal cancer. This risk has been estimated to reach about 7% at 20 years of disease, 7-14% at 25 years, and as high as 30% after 35 years. The guidelines for the management of inflammatory bowel disease recommend endoscopic resection of circumscribed dysplasia and ongoing colonoscopic surveillance as a reasonable strategy in patients with ulcerative colitis. Read More

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December 2018

Uncovering metastability and disassembly hotspots in whole viral particles.

Prog Biophys Mol Biol 2018 Dec 13. Epub 2018 Dec 13.

Department of Biological Sciences, National University of Singapore, 117543, Singapore. Electronic address:

Viruses are metastable macromolecular assemblies that toggle between multiple conformational states through molecular rearrangements that are critical for mediating viral host entry. Viruses respond to different host specific environmental cues to form disassembly intermediates for the eventual release of genomic material required for replication. Although static snapshots of these intermediates have been captured through structural techniques such as X-ray crystallography and cryo-EM, the mechanistic details of these conformational rearrangements underpinning viral metastability have been poorly understood. Read More

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December 2018

Long-term outcomes following minimally invasive and open esophagectomy in Finland: A population-based study.

Eur J Surg Oncol 2018 Dec 7. Epub 2018 Dec 7.

Research Center of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.

Background: Studies of long-term survival after minimally invasive and open esophagectomy are needed. The aim of this study was to compare long-term outcomes following minimally invasive and open esophagectomy for esophageal cancer at the population level.

Methods: All patients undergoing minimally invasive (n = 159) or open transthoracic (n = 431) esophagectomy for esophageal cancer in Finland between 2004 and 2014 were identified from nationwide registries. Read More

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December 2018

Oral core-needle biopsy in the diagnosis of malignant parapharyngeal space tumors.

Am J Otolaryngol 2018 Nov 22. Epub 2018 Nov 22.

Department of Otolaryngology-Head and Neck, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.

Objective: To confirm the pre-treatment diagnosis of parapharyngeal space malignancy could aid the treatment plan.

Methods: For patients with suspected malignant parapharyngeal space tumors following preoperative imaging, oral biopsy was conducted for pathological diagnosis with the use of 22-G biopsy needles.

Results: A total of 11 patients were enrolled. Read More

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November 2018

Prospective US investigational device exemption trial of a sutureless aortic bioprosthesis: One-year outcomes.

J Thorac Cardiovasc Surg 2018 Oct 23. Epub 2018 Oct 23.

Department of Thoracic and Cardiovascular Surgery, Heart and Vascular Institute, Cleveland Clinic Abu Dhabi and Cleveland Clinic Foundation, Cleveland, Ohio.

Objectives: We performed a prospective, single-arm clinical trial approved under a Food and Drug Administration Investigational Device Exemption to assess safety and efficacy of Perceval, a sutureless bovine pericardial aortic valve representing the initial US experience.

Methods: From June 2013 to January 2015, 300 patients (mean age 76.7 ± 7. Read More

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October 2018
2 Reads

The lack of a magic bullet.

J Thorac Cardiovasc Surg 2018 Nov 8. Epub 2018 Nov 8.

Department of Minimally Invasive Cardiac Surgery, Cardiothoracic Center, Istituto Clinico Sant'Ambrogio, Milan, Italy. Electronic address:

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November 2018

Chronic hypokalemia due to gastric exclusion after bariatric surgery.

J Visc Surg 2018 Dec 12. Epub 2018 Dec 12.

Department of Minimally Invasive Digestive Surgery, Antoine Béclère Hospital, 157, rue de la Porte-de-Trivaux, 92141 Clamart, France. Electronic address:

Hypokalemia is a common complication of repeated vomiting or prolonged gastric suction. In the case we observed, a patient presented with chronic hypokalemia due to gastric dilatation and the development of a superior mesenteric artery syndrome several years after gastric banding. This paper presents pre-operative and post-operative illustrations of a rare but potentially serious entity. Read More

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December 2018

Persistent atrial fibrillation: A systematic review and meta-analysis of invasive strategies.

Int J Cardiol 2018 Nov 29. Epub 2018 Nov 29.

Amsterdam UMC, University of Amsterdam, Department of Cardiology, Heart Center, Meibergdreef 9, Amsterdam, the Netherlands. Electronic address:

Background: Persistent atrial fibrillation (AF) is associated with higher stroke and mortality risk than paroxysmal AF (pAF). Outcomes of catheter or surgical ablation are worse in patients with persistent AF than in pAF, and the optimal invasive rhythm control strategy has not been established.

Purpose: We provide a contemporary systematic overview on efficacy and safety of catheter and minimally-invasive surgical ablation for persistent AF. Read More

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November 2018

Efficacy and Safety of Non-Invasive Intravesical Instillation of Onabotulinum Toxin-A for Overactive Bladder and Interstitial Cystitis/Bladder Pain Syndrome: Systematic Review and Meta-analysis.

Urology 2018 Dec 12. Epub 2018 Dec 12.

Department of Urology, Soonchunhyang University Seoul Hospital, Soonchunhyang University Medical College, Seoul, South Korea. Electronic address:

Objective: To investigate the efficacy and safety of non-invasive intravesical instillation of OBTX-A through systematic review and meta-analysis. Recently, several studies of non-invasive intravesical instillation of Onabotulinum Toxin-A (OBTX-A) have been published. However, its efficacy is not well validated yet compared to well-known efficacy of minimally invasive intravesical injection of OBTX-A. Read More

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December 2018
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Case series of hypotony maculopathy after CyPass insertion treated with intra-luminal suture occlusion.

Clin Exp Ophthalmol 2018 Dec 15. Epub 2018 Dec 15.

Glaucoma Service, Moorfields Eye Hospital, London EC1V 2PD, United Kingdom. UCL Institute of Ophthalmology, London, United Kingdom.

The CyPass Micro-Stent (Alcon, Fort Worth, USA) is a minimally invasive glaucoma surgical (MIGS) device, implanted into the supra-choroidal space. The CyPass was FDA approved in July 2016 and CE marked in Europe. It was withdrawn voluntarily by the manufacturer in August 2018. Read More

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December 2018

Downregulation of long noncoding RNA DGCR5 contributes to the proliferation, migration, and invasion of cervical cancer by activating Wnt signaling pathway.

J Cell Physiol 2018 Dec 14. Epub 2018 Dec 14.

Department of Pathology, Huai'an Maternal and Child Health Care Center of Jiangsu Province Affiliated Hospital of Yangzhou University, Huai'an, China.

Accumulating research works have reported that long noncoding RNAs (lncRNAs) are involved in various cancers, including cervical cancer. LncRNA DGCR5 has been identified in many cancers. However, the biological role of DGCR5 in cervical cancer remains barely known. Read More

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December 2018
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Pathoanatomy of Maisonneuve fracture based on radiologic and CT examination.

Arch Orthop Trauma Surg 2018 Dec 14. Epub 2018 Dec 14.

Department of Orthopaedics, First Faculty of Medicine, Charles University and Military University Hospital Prague, U Vojenské Nemocnice 1200, 169 02, Prague 6, Czech Republic.

Introduction: Although Maisonneuve fracture (MF) is a well-known type of ankle fracture-dislocation, there is still a lack of information about the epidemiology and the extent of all associated injuries. The aim of study is to describe MF pathoanatomy on the basis of radiographs, CT scans and intraoperative findings.

Materials And Methods: The study comprised 54 adult patients. Read More

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December 2018

Stent-screw-assisted internal fixation: the SAIF technique to augment severe osteoporotic and neoplastic vertebral body fractures.

J Neurointerv Surg 2018 Dec 14. Epub 2018 Dec 14.

Department of Neuroradiology, Papa Giovanni XXIII Hospital, Bergamo, Italy.

Objectives: To describe a new technique to obtain minimally invasive but efficient vertebral body (VB) reconstruction, augmentation, and stabilization in severe osteoporotic and neoplastic fractures, combining two pre-existing procedures. The implant of vertebral body stents (VBS) is followed by insertion of percutaneous, fenestrated, cement-augmented pedicular screws that act as anchors to the posterior elements for the cement/stent complex. The screws reduce the risk of stent mobilization in a non-intact VB cortical shell and bridge middle column and pedicular fractures. Read More

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December 2018

Evaluation of retraction time as a predictor of postoperative motor dysfunction after minimally invasive transpsoas interbody fusion at L4-L5.

J Clin Neurosci 2018 Dec 11. Epub 2018 Dec 11.

MedStar Georgetown University Hospital, Department of Neurosurgery, Washington, D.C, United States. Electronic address:

Background: Complications associated with the lateral lumbar transpsoas approach largely comprise various nerve-related syndromes particularly at L4-5. Quadriceps weakness can occur from stretch injury to the femoral nerve during retraction.

Objective: The purpose of this study is to evaluate the role of retraction time in the development of postoperative neuropathic motor weakness at the L4-5 level. Read More

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December 2018

Epicardial pacemaker implantation in small animals.

J Vet Cardiol 2018 Dec 11. Epub 2018 Dec 11.

Department of Clinical Sciences, Colorado State University, Fort Collins, CO, 80525, USA. Electronic address:

Epicardial pacemaker implantation can be performed as a lone procedure or in combination with another thoracic or abdominal surgery. This article reviews the current literature and describes a minimally invasive approach for epicardial pacemaker implantation in small animals. The principal advantage of epicardial pacing is that it avoids contact with blood and intracardiac structures and thereby avoids uncommon but potentially devastating complications associated with endocardial pacemaker implantation. Read More

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December 2018
1 Read

Robot assisted minimally invasive esophagectomy (RAMIE) for esophageal cancer.

Best Pract Res Clin Gastroenterol 2018 Oct - Dec;36-37:81-83. Epub 2018 Nov 29.

Department of Surgery, G04.228, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, the Netherlands.

Worldwide, the standard treatment for locally advanced esophageal cancer with curative intent is perioperative chemotherapy or preoperative chemoradiotherapy followed by open transthoracic esophagectomy (OTE) with gastric conduit reconstruction. Minimally invasive esophagectomy (MIE) was developed to improve the postoperative outcome by reducing the surgical trauma, with comparable short-term oncologic results. However, MIE is a highly complex procedure associated with a long learning curve. Read More

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November 2018
1 Read

Oesophagectomy: The expanding role of minimally invasive surgery in oesophageal cancer.

Best Pract Res Clin Gastroenterol 2018 Oct - Dec;36-37:75-80. Epub 2018 Nov 21.

Department of Upper GI Surgery and General Surgery, Norfolk and Norwich University Hospital, Colney Lane, NR4 7UY, Norwich, United Kingdom. Electronic address:

Historically, open oesophagectomy was the gold standard for oesophageal cancer surgery. This was associated with a relatively higher morbidity. In the last two decades, we have seen significant improvements in short and long term outcomes due to centralisation of oesophagectomy, multidisciplinary approach, enhanced recovery after surgery programmes, neoadjuvant treatments and advances in minimally invasive oesophagectomy (MIO) techniques. Read More

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November 2018

Sleep Quality and its Main Determinants Among Staff in a Persian Private Hospital.

Arch Iran Med 2018 Nov 1;21(11):524-529. Epub 2018 Nov 1.

Pars Advanced and Minimally Invasive Medical Manners Research Center, Pars Hospital, Iran University of Medical Sciences, Tehran, Iran.

Background: Having good quality of sleep is essential to good health. Sleep disorders could incur intangible expenses. The aim of this cross-sectional study was to evaluate the Persian version of the Pittsburgh Sleep Quality Index (PSQI-P) questionnaire administered to 3 categories of workers (clinical personnel, clerical staff, and logistics workers) in a private hospital located in Tehran, Iran. Read More

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November 2018
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EG-VEGF silencing inhibits cell proliferation and promotes cell apoptosis in pancreatic carcinoma via PI3K/AKT/mTOR signaling pathway.

Biomed Pharmacother 2019 Jan 5;109:762-769. Epub 2018 Nov 5.

Department of Hepatobiliary Surgery, General Hospital of Ningxia Medical University, Yinchuan 750001, China. Electronic address:

Objective: Pancreatic carcinoma (PC), one of the most prevalent and malignant tumors, has a poor prognosis and a high mortality rate. EG-VEGF, a vascular endothelial growth factor from endocrine glands, also termed as PROK1, has a high positive expression rate in PC tissues and is involved in the pathogenesis of various tumors. However, the expression and potential role of EG-VEGF in PC has not been thoroughly explored. Read More

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January 2019
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Comparative Analysis of the Exposure and Surgical Freedom of the Endoscopic Extended Minipterional Craniotomy and the Transorbital Endoscopic Approach to the Anterior and Middle Cranial Fossae.

Oper Neurosurg (Hagerstown) 2018 Dec 14. Epub 2018 Dec 14.

Department of Neurosurgery, The Ohio State University Wexner Medical Center, Columbus, Ohio.

Background: Numerous minimally invasive approaches to the skull base have been successively developed. Knowledge of the surgical nuances of a specific approach may facilitate approach selection. This study sought to compare the nuances of an extended version of the minipterional craniotomy (EMPT) with those of the transorbital endoscopic approach (TOEA) to the anterior and middle cranial fossae (ACF and MCF, respectively). Read More

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December 2018
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Challenges and Demand for Modeling Disorders of Consciousness following Traumatic Brain Injury.

Neurosci Biobehav Rev 2018 Dec 11. Epub 2018 Dec 11.

Center for Brain Injury & Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States; Center for Neurotrauma, Neurodegeneration & Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, United States; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, United States. Electronic address:

Following severe traumatic brain injury (TBI), many patients experience coma - an unresponsive state lacking wakefulness or awareness. Coma rarely lasts more than two weeks, and emergence involves passing through a state of wakefulness without awareness of self or environment. Patients that linger in these Disorders of Consciousness (DoC) undergo clinical assessments of awareness for diagnosis into Unresponsive Wakefulness Syndrome (no awareness, also called vegetative state) or Minimally Conscious State (periodic increases in awareness). Read More

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December 2018

De-intensified adjuvant (chemo)radiotherapy versus standard adjuvant chemoradiotherapy post transoral minimally invasive surgery for resectable HPV-positive oropharyngeal carcinoma.

Cochrane Database Syst Rev 2018 Dec 14;12:CD012939. Epub 2018 Dec 14.

ENT Department, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge, UK, CB2 0QQ.

Background: More than 400,000 cases of oropharyngeal squamous cell cancer (OPSCC) are diagnosed every year worldwide and this is rising. Much of the increase has been attributed to human papillomavirus (HPV). HPV-positive OPSCC patients are often younger and have significantly improved survival relative to HPV-negative patients. Read More

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December 2018
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Technique of Fractionated Transcatheter Arterial Embolization for Treating Large Arteriovenous Malformation in Brain Functional Area.

J Craniofac Surg 2018 Dec 13. Epub 2018 Dec 13.

Department of Neurosurgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing.

Objective: At present, large cranial function area arteriovenous malformation (fAVM) is mainly treated by craniotomy with a high risk of operation and high disability. In recent years, with the continuous improvement of the neural intervention technology, fractionated transcatheter arterial embolization (fTAE) may be used to treat the fAVM instead of surgical treatment. However, its effectiveness for treating fAVM has never been explored. Read More

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December 2018

[Assistant cooperation and therapeutic effect analysis in transoral robotic surgery with da Vinci surgical system].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Jul;32(14):1074-1077

Department of Otolaryngology Head and Neck Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China.

The purpose of this study was to summarize the therapeutic effect and key points and skills of assistant cooperation in transoral robotic surgery (TORS) with da Vinci surgical system.Forty patients were reviewed who were treated with TORS in Beijing Anzhen Hospital from June 1, 2016 to May 30, 2018. Key points of assistant cooperation, docking time, incidence of transit to open approach, mechanical failure, complications, and negative surgical margin were analyzed. Read More

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July 2018
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[Preliminary experience of transoral robotic surgery in laryngeal and hypopharyngeal tumors with da Vinci surgical system].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Jul;32(14):1065-1070

Department of Otolaryngology Head and Neck Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China.

The purpose of this study was to summarize preliminary clinical experience of transoral robotic surgery (TORS) in laryngeal and hypopharyngeal tumors with da Vinci surgical system.Twelve patients were reviewed who were diagnosed with laryngeal (=7) and hypopharyngeal tumors (=5) and treated with TORS in Beijing Anzhen Hospital from July 1, 2016 to January 31, 2018.Ten cases were male and two cases were female. Read More

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