1,413 results match your criteria Minimally Invasive Surgery of the Parathyroid


Letter to Editor: Comparison Between the Protector™ Laryngeal Mask Airway and the Endotracheal Tube for Minimally Invasive Thyroid and Parathyroid Surgery.

World J Surg 2020 Jul 1. Epub 2020 Jul 1.

Second Department of Propedeutic Surgery, Medical School, Laikon General Hospital, National and Kapodistrian University of Athens, Athens, Greece.

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http://dx.doi.org/10.1007/s00268-020-05662-4DOI Listing

FGF23 and primary hyperparathyroidism: is there a link?

Endokrynol Pol 2020 Jun 29. Epub 2020 Jun 29.

Grigore. T. Popa University of Medicine and Pharmacy, 16 Universitatii Street, 700115 Iasi, Romania.

Introduction: Data regarding the role of FGF23 in primary hyperparathyroidism (PHPT) are scarce and discordant. Our study aimed at evaluating the prognostic impact of FGF23 upon the clinical and biochemical evolution of PHPT.

Materials And Methods: 42 patients with ages between 30 - 80 years diagnosed with PHPT caused by a sporadic, solitary parathyroid adenoma and referred to surgery (minimally invasive parathyroidectomy) were prospectively included in the study. Read More

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http://dx.doi.org/10.5603/EP.a2020.0030DOI Listing

A Randomized Comparison of Carbon Nanoparticles in Endoscopic Lymph Node Dissection Via the Bilateral Areola Approach for Papillary Thyroid Cancer.

Surg Laparosc Endosc Percutan Tech 2020 Apr 21. Epub 2020 Apr 21.

Division of Thyroid Surgery, China-Japan Union Hospital of Jilin University, Jilin Provincial Key Laboratory of Surgical Translational Medicine, Jilin Provincial Precision Medicine Laboratory of Molecular Biology and Translational Medicine on Differentiated Thyroid Carcinoma.

Objective: We assess the value of carbon nanoparticles (CNP) staining in patients undergoing endoscopic thyroidectomy and central compartment lymph node (CLN) dissection via the bilateral areola approach [endoscopic thyroidectomy via bilateral areola approach (ETBAA)].

Methods: This was a prospective randomized study. Three hundred two consecutive early-stage thyroid cancer patients eligible for ETBAA were recruited at the Division of Thyroid Surgery, China-Japan Union Hospital, Jilin University, China. Read More

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http://dx.doi.org/10.1097/SLE.0000000000000793DOI Listing

How to do depends on where it settles: Mediastinal parathyroid adenomas.

Turk Gogus Kalp Damar Cerrahisi Derg 2019 Jun 22;28(2):340-346. Epub 2020 Apr 22.

Department of Thoracic Surgery, Gülhane Training and Research Hospital, Ankara, Turkey.

Background: In this study, we aimed to evaluate demographic characteristics, preoperative adenoma localization, surgical techniques selected according to the size and localization of adenoma, and clinical results of patients undergoing mediastinal parathyroid adenoma excision.

Methods: Medical records of a total of 11 patients (4 males, 7 females; mean age 52.6 years; range, 25 to 65 years) who underwent excision of mediastinal parathyroid adenoma in our clinic between January 2011 and June 2019 were retrospectively reviewed. Read More

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http://dx.doi.org/10.5606/tgkdc.dergisi.2020.18764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7298376PMC

F-choline PET/4D CT in hyperparathyroidism: correlation between biochemical data and study parameters.

Rev Esp Med Nucl Imagen Mol 2020 Jun 12. Epub 2020 Jun 12.

Sección Cirugía de Cabeza y Cuello, Servicio de Cirugía General, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.

Background: Hyperparathyroidism (HPT) is characterised by increased levels of parathyroid hormone (HPT), surgical excision being the only definitive curative option. After establishing the need for surgery, it is essential to identify the parathyroid glands in the preoperative period to use a minimally invasive approach. Negativity and / or discrepancy in first-line studies (ultrasound and Tc-99m MIBI parathyroid scintigraphy) require more accurate images to reduce the likelihood of bilateral cervical exploration or reintervention. Read More

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http://dx.doi.org/10.1016/j.remn.2020.03.017DOI Listing

Ultrasound dye-assisted parathyroidectomy (USDAP): Experience of a tertiary center.

Am J Otolaryngol 2020 May 29:102558. Epub 2020 May 29.

Department of Otorhinolaryngology and Head and Neck Surgery, European Institute of Oncology, IRCCS, Via Ripamonti 435, 20141 Milan, Italy.

Background: Primary hyperparathyroidism is primarily caused by parathyroid adenoma, followed by hyperplasia and parathyroid carcinoma. In the era of minimally invasive, targeted parathyroidectomy, the main challenge remains that of distinguishing intraoperatively pathological parathyroid from normal glands and peri-thyroid fat tissue. The aim of this study is to evaluate the surgical outcomes of a novel minimally invasive technique called ultrasound-guided dye-assisted parathyroidectomy (USDAP). Read More

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http://dx.doi.org/10.1016/j.amjoto.2020.102558DOI Listing

Use of Alexis wound retractor in minimally invasive parathyroid surgery.

Ann R Coll Surg Engl 2020 Jun 5. Epub 2020 Jun 5.

Eastbourne District General Hospital, Eastbourne, UK.

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http://dx.doi.org/10.1308/rcsann.2020.0124DOI Listing

The use of computed tomography as a first-line imaging modality in patients with primary hyperparathyroidism.

Hormones (Athens) 2020 May 13. Epub 2020 May 13.

Centre for Endocrine Surgery, University College London Hospital, 235 Euston Road, London, NW1 2BU, UK.

Background: The success of minimally invasive parathyroidectomy (MIP) relies on accurate localization of the abnormal parathyroid glands. Concordant findings on ultrasound (US) and Tc-scintigraphy (sestamibi) are currently considered the 'gold standard'. Computed tomography (CT) has also recently been used in preoperative planning. Read More

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http://dx.doi.org/10.1007/s42000-020-00205-xDOI Listing

ARE THYROID NODULES AN OBSTACLE TO MINIMAL INVASIVE PARATHYROID SURGERY? A SINGLE-CENTER STUDY FROM AN ENDEMIC GOITER REGION.

Acta Endocrinol (Buchar) 2019 Oct-Dec;15(4):531-536

TC Saglik Bakanligi, Ankara Numune Training and Research Hospital - Surgery, Altindag, Ankara, Turkey.

Context: Minimally invasive parathyroidectomy (MIP) procedure has become a widely accepted alternative to the standard four-gland exploration nowadays.

Objective: The aim of this study was to evaluate patients with primary hyperparathyroidism (PHPT), who had been treated with thyroidectomy and bilateral neck exploration (BNE), rather than MIP alone, due to coexisting thyroid nodules and to determine the benefits of simultaneous thyroidectomy and the possible negative outcomes of not performing this additional procedure.

Design: There were 185 patients who were operated for PHPT at our clinic from January 2014 to November 2016. Read More

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http://dx.doi.org/10.4183/aeb.2019.531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200102PMC

Main Surgical Principles and Methods in Surgical Treatment of Primary Hyperparathyroidism.

Sisli Etfal Hastan Tip Bul 2019 3;53(4):337-352. Epub 2019 Dec 3.

Department of Genaral Surgery, Bahcesehir University, Faculty of Medicine, Istanbul, Turkey.

The only curative treatment for primary hyperparathyroidism (pHPT) is surgery. The most important factors that increase the success rate of a parathyroidectomy are the establishment of the correct diagnosis and the surgeon's good knowledge of anatomy and embryology. The lower parathyroid glands develop from the dorsal portion of the third pharyngeal pouch, and the upper parathyroid glands from the fourth pharyngeal pouch. Read More

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http://dx.doi.org/10.14744/SEMB.2019.67944DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192302PMC
December 2019

Intraoperative Adjunct Methods for Localization in Primary Hyperparathyroidism.

Sisli Etfal Hastan Tip Bul 2019 11;53(2):84-95. Epub 2019 Jul 11.

Department of General Surgery, Health Sciences University, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey.

Primary hyperparathyroidism (pHPT) is a frequently seen endocrine disease, and its main treatment is surgery. In the majority of pHPT, the disease involves only a single gland, and the majority of the pathological glands can be determined by preoperative localization methods.In addition to preoperative localization studies in parathyroidectomy, the use of adjunct methods to improve intraoperative localization in order to increase success of surgery is becoming widespread. Read More

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http://dx.doi.org/10.14744/SEMB.2019.37542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199831PMC

The transcutaneous electromyography recording method for intraoperative neuromonitoring of recurrent laryngeal nerve during minimally invasive parathyroidectomy.

Sci Rep 2020 May 6;10(1):7609. Epub 2020 May 6.

Department of Otorhinolaryngology, E-Da Hospital, I-Shou University, Kaohsiung, Taiwan.

Intraoperative neuromonitoring (IONM) facilitates recurrent laryngeal nerve (RLN) protection in thyroid and parathyroid surgeries. This study aimed to investigate a novel transcutaneous electromyography (EMG) recording method for IONM of the RLN during minimally invasive parathyroidectomy (MIP). Twenty patients with primary hyperparathyroidism undergoing MIP were enrolled. Read More

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http://dx.doi.org/10.1038/s41598-020-64675-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203296PMC

Preoperative parathyroid localization does not improve surgical outcomes for patients with primary hyperparathyroidism.

Am J Surg 2020 Apr 25. Epub 2020 Apr 25.

The Department of Surgery, The University of Alabama at Birmingham, Birmingham, AL, USA. Electronic address:

Background: Most patients with primary hyperparathyroidism undergo localization prior to operation with variable success. Therefore, in this study we investigated the safety of parathyroidectomy without imaging.

Methods: A prospective database of 2057 surgical patients with primary hyperparathyroidism from 2001 to 2019 was reviewed. Read More

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http://dx.doi.org/10.1016/j.amjsurg.2020.04.029DOI Listing

Transoral endocrine surgery: Considerations for adopting a new technique.

J Surg Oncol 2020 Jul 25;122(1):36-40. Epub 2020 Apr 25.

Division of General Surgery, Department of Surgery, Section of Endocrine Surgery, Baylor College of Medicine, Houston, Texas.

Transoral endocrine surgery encompasses a group of operations whereby the thyroid or parathyroid gland is removed through the oral vestibule. This operation has the advantage of leaving no cutaneous scar and a risk profile similar to open surgery. Adoption of this technique has increased dramatically over the last several years. Read More

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http://dx.doi.org/10.1002/jso.25953DOI Listing

Preoperative and Intraoperative Methods of Parathyroid Gland Localization and the Diagnosis of Parathyroid Adenomas.

Molecules 2020 Apr 9;25(7). Epub 2020 Apr 9.

Section of Endocrinology, Andrology and Metabolic Diseases, Department of Emergency and Organ Transplantations, University of Bari "Aldo Moro" Medical School, 70124 Bari, Italy.

Accurate pre-operative determination of parathyroid glands localization is critical in the selection of minimally invasive parathyroidectomy as a surgical treatment approach in patients with primary hyperparathyroidism (PHPT). Its importance cannot be overemphasized as it helps to minimize the harmful side effects associated with damage to the parathyroid glands such as in hypocalcemia, severe hemorrhage or recurrent laryngeal nerve dysfunction. Preoperative and intraoperative methods decrease the incidence of mistakenly injuring the parathyroid glands and allow for the timely diagnosis of various abnormalities, including parathyroid adenomas. Read More

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http://dx.doi.org/10.3390/molecules25071724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181220PMC

Comparison of Tc-MIBI planar scintigraphy, SPET/CT and ultrasonography in detection of parathyroid adenoma in patients with primary hyperparathyroidism.

Hell J Nucl Med 2020 Jan-Apr;23(1):21-26. Epub 2020 Mar 31.

Ankara Yildirim Beyazit University, Faculty of Medicine, Department of Nuclear Medicine, Ankara, Turkey.

Objective: Primary hyperparathyroidism (PHPT) is a common endocrine disease that is caused by a single adenoma in most of the cases. Surgical management is the mainstay and definitive treatment for parathyroid adenoma (PA). Minimally invasive surgical techniques are as effective as bilateral neck exploration with a lower risk of complications and better cosmetic results in patients with solitary PA. Read More

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http://dx.doi.org/10.1967/s002449912002DOI Listing

Energy-based devices for hemostasis in thyroid surgery.

Gland Surg 2020 Feb;9(Suppl 2):S153-S158

Department of Endocrine Surgery, Third Chair of General Surgery, Jagiellonian University Medical College, Krakow, Poland.

The evolution of operative techniques in thyroid surgery that has taken place over the past several decades would not have been possible if not for a sui generis revolution in surgery at the turn of the 19th and 20th centuries. The three most important events of the end of the 19th century, i.e. Read More

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http://dx.doi.org/10.21037/gs.2019.10.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044082PMC
February 2020

Surgical implications of recent modalities for parathyroid imaging.

Gland Surg 2020 Feb;9(Suppl 2):S86-S94

Department of Endocrine Surgery, Third Chair of General Surgery, Jagiellonian University Medical College, Krakow, Poland.

Clinical or subclinical primary hyperparathyroidism (PHPT) is one of the most common endocrine disorders in the world. Parathyroidectomy is the treatment of choice in symptomatic patients, stabilizing the progression of complications caused by the destruction activity of parathyroid hormone (PTH). Parathyroid surgical techniques have evolved over the years from bilateral neck exploration, to minimally invasive single parathyroid gland exploration, to minimally invasive video-assisted parathyroidectomy. Read More

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http://dx.doi.org/10.21037/gs.2019.11.10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044083PMC
February 2020

Endoscopic parathyroidectomy: a retrospective review of 27 cases.

Surg Endosc 2020 Mar 12. Epub 2020 Mar 12.

Department of General Surgery, Grant Medical College & Sir JJ Group of Hospitals, Mumbai, India.

Background: Primary hyperparathyroidism is a common endocrine disorder with adenomas being the most frequent cause. The condition is conventionally treated by a bilateral neck exploration through a cervical incision with removal of the affected glands. Intra-operative parathyroid hormone (IOPTH) monitoring and pre-operative Tc99m MIBI scans are facilitating focused approaches like minimally invasive video-assisted parathyroidectomy (MiVAP) and totally endoscopic parathyroidectomy (TOEP). Read More

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http://dx.doi.org/10.1007/s00464-020-07500-zDOI Listing

Fine-needle aspiration washout in the diagnosis of cystic parathyroid adenoma.

BMJ Case Rep 2020 Mar 10;13(3). Epub 2020 Mar 10.

Department of Endocrine Surgery, Scientific Center of Surgery named after M.A.Topchubashov, Baku, Azerbaijan.

Cystic parathyroid adenomas are one of the rare causes of neck masses. Due to its rarity, it causes misdiagnosis and wrong treatments and has undesirable consequences. The measurement of parathyroid hormone in fine-needle aspiration washout fluid is a minimally invasive, safe method for the diagnosis of parathyroid cysts and seems to be more useful than Tc-99m sestamibi (MIBI) parathyroid single photon emission computed tomography (SPECT)/CT. Read More

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http://dx.doi.org/10.1136/bcr-2019-234084DOI Listing

[A Case of Giant Parathyroid Adenoma].

Gan To Kagaku Ryoho 2019 Dec;46(13):2051-2053

Division of Breast and Endocrine Surgery, Dept. of Surgery, Nihon University School of Medicine.

A 79-year-old man presenting with general fatigue was admitted to our department. Preoperative laboratory examination indicated primary hyperparathyroidism as the cause of his symptoms, with elevated parathormone and serum calcium levels. Ultrasound and 99mTc-MIBI of the cervical region revealed a giant parathyroid adenoma, sized 4×2. Read More

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December 2019

Surgical options in treating patients with primary hyperparathyroidism.

Radiol Oncol 2020 Feb 29;54(1):22-32. Epub 2020 Feb 29.

Institute of Oncology Ljubljana, Ljubljana, Slovenia.

Background Primary hyperparathyroidism is the third most common endocrine disorder for which surgical procedure called parathyroidectomy is the most effective treatment. Since the early 20th century, parathyroid surgery has improved extensively. With the advances in preoperative imaging and with understanding the causes of disease, new and minimally invasive surgical approaches overrode the standard bilateral exploratory operations. Read More

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http://dx.doi.org/10.2478/raon-2020-0010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087427PMC
February 2020

Neural monitoring in thyroid surgery is here to stay.

Gland Surg 2020 Jan;9(Suppl 1):S43-S46

Division of Thyroid Surgery, Jilin Provincial Key Laboratory of Surgical Translational Medicine, Jilin Provincial Precision Medicine Laboratory of Molecular Biology and Translational Medicine on Differentiated Thyroid Carcinoma, China-Japan Union Hospital Of Jilin University, Changchun 130000, China.

The iatrogenic injury of the recurrent laryngeal nerve (RLN), more clinically significant than those affecting the external branch of the superior laryngeal nerve (EBSLN), constitute one of the most feared perioperative complications of thyroid surgery and parathyroid glands, in terms of impact in clinical and economic-social costs. Moreover, these events rank among the leading reasons for medicolegal litigation of surgeons because of its attendant reduction in quality of life. The average incidence of RLN paralysis, permanent and temporary, after thyroidectomy is high and stands between 2. Read More

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http://dx.doi.org/10.21037/gs.2019.10.24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995897PMC
January 2020

Day case parathyroidectomy: is this the right way for the patients?

Gland Surg 2020 Jan;9(Suppl 1):S6-S13

UO Endocrinochirurgia, Università di Pisa, Pisa, Italy.

Background: Minimally-invasive video-assisted parathyroidectomy (MIVAP) can be considered as the primary treatment of choice for single parathyroid adenoma. Often, this technique is performed in a day surgery setting and is associated with regional anaesthesia (RA). Many studies have already reported the feasibility and safety of MIVAP in day surgery. Read More

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http://dx.doi.org/10.21037/gs.2019.09.02DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995900PMC
January 2020

Ultrasound-guided percutaneous injection of Pseudomonas aeruginosa-mannose sensitive hemagglutinin for treatment of chyle fistula following neck dissection: Two case reports.

Medicine (Baltimore) 2020 Jan;99(5):e18816

Department of Thyroid and Parathyroid Surgery Center.

Rationale: Chyle fistula is a rare but troublesome complication of neck dissection. Topical application of Pseudomonas aeruginosa-mannose sensitive hemagglutinin (PA-MSHA) injection has been reported as a novel, viable, and effective approach in the treatment of chyle fistula following neck dissection. However, there have been no reports regarding the treatment of chyle fistula using ultrasound (US)-guided percutaneous injection of PA-MSHA. Read More

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http://dx.doi.org/10.1097/MD.0000000000018816DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004758PMC
January 2020
5.723 Impact Factor

Transoral thyroid surgery vestibular approach: does size matter anymore?

J Endocrinol Invest 2020 May 28;43(5):615-622. Epub 2020 Jan 28.

Department of General, Abdominal and Vascular Surgery, Hospital Agatharied GmbH, Hausham, Germany.

Background: Various approaches for endoscopic and minimally invasive thyroid operations have been reported, with some becoming popular to date. The aim of these procedures is to reduce and prevent visible scars in the neck. This led to the transoral endoscopic thyroidectomy vestibular approach (TOETVA) technique applicable in small thyroid specimen. Read More

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http://dx.doi.org/10.1007/s40618-019-01149-9DOI Listing

Severe peripheral arterial diseases in hemodialysis patient: A case report.

Medicine (Baltimore) 2020 Jan;99(4):e18760

Department of Nephrology, University of South China affiliated Changsha Central Hospital.

Rationale: Peripheral arterial diseases (PADs) is defined as a systemic arterial disorders involving the lower extremity arteries, iliac, and carotid, which is developed more common in patients with chronic kidney disease (CKD) than individual with normal renal function. Concurrence of mesenteric artery disease and lower extremity artery disease (LEAD) is rare. The presence of PADs in patients receiving hemodialysis leads to a dramatic increase in risk of cardiovascular mortality. Read More

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http://dx.doi.org/10.1097/MD.0000000000018760DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004584PMC
January 2020
5.723 Impact Factor

Risk Factors and Treatment Options for Persistent Hyperparathyroidism After Kidney Transplantation.

Transplant Proc 2020 Jan - Feb;52(1):157-161. Epub 2020 Jan 7.

Department of General Surgery Division of Transplantation, Baskent University, Ankara, Turkey. Electronic address:

Background: Kidney transplantation (KT) corrects secondary hyperparathyroidism. However, persistent hyperparathyroidism (pHPT) may be observed in some patients post-KT. This study aims to evaluate the risk factors and treatment options for pHPT. Read More

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http://dx.doi.org/10.1016/j.transproceed.2019.11.020DOI Listing

Intraoperative Parathyroid Hormone Monitoring in the Surgical Management of Sporadic Primary Hyperparathyroidism.

Endocrinol Metab (Seoul) 2019 12;34(4):327-339

Division of Endocrine Surgery, DeWitt Daughtry Family Department of Surgery, University of Miami Leonard M. Miller School of Medicine, Miami, FL, USA.

Intraoperative parathyroid hormone monitoring (IPM) has been shown to be a useful adjunct during parathyroidectomy to ensure operative success at many specialized medical centers worldwide. Using the Miami or ">50% intraoperative PTH drop" criterion, IPM confirms the complete excision of all hyperfunctioning parathyroid tissue before the operation is finished, and helps guide the surgeon to identify additional hyperfunctioning parathyroid glands that may necessitate further extensive neck exploration when intraoperative parathyroid hormone (PTH) levels do not drop sufficiently. The intraoperative PTH assay is also used to differentiate parathyroid from non-parathyroid tissues during operations using fine needle aspiration samples and to lateralize the side of the neck harboring the hypersecreting parathyroid through differential jugular venous sampling when preoperative localization studies are negative or equivocal. Read More

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http://dx.doi.org/10.3803/EnM.2019.34.4.327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935782PMC
December 2019

Intraoperative Indocyanine Green (ICG) Angiography for the Identification of the Parathyroid Glands: Current Evidence and Future Perspectives.

In Vivo 2020 Jan-Feb;34(1):23-32

Laboratory of Experimental Surgery and Surgical Research "N.S. Christeas", National and Kapodistrian University of Athens Medical School, Athens, Greece.

Background/aim: Recently, indocyanine green (ICG) fluorescence imaging has been used for the identification of the parathyroid glands (PG) during thyroid and parathyroid surgery. However, an overall consensus on the optimal technique, the dosage, the timing of the ICG administration and finally its interpretation and clinical usefulness is still lacking evidence. The aim of this review is to investigate the use of ICG angiography during thyroidectomy and/or parathyroidectomy for identification as well as for the perfusion integrity of the parathyroid glands. Read More

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http://dx.doi.org/10.21873/invivo.11741DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984100PMC

Video-assisted thoracoscopic surgery for ectopic mediastinal parathyroid adenoma.

BJS Open 2019 12 19;3(6):743-749. Epub 2019 Aug 19.

Department of Endocrine Surgery Imperial College Healthcare NHS Trust London UK.

Background: Primary hyperparathyroidism (PHPT), caused by an ectopic mediastinal parathyroid adenoma, is uncommon. In the past, when the adenoma was not accessible from the neck, median sternotomy was advocated for safe and successful parathyroidectomy. Video-assisted thoracoscopic surgical (VATS) parathyroidectomy represents a modern alternative approach to this problem. Read More

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http://dx.doi.org/10.1002/bjs5.50207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887896PMC
December 2019

Comparison of parathyroid hormone kinetics in endoscopic thyroidectomy via bilateral areola with open thyroidectomy.

BMC Surg 2019 Dec 11;19(1):190. Epub 2019 Dec 11.

Department of Thyroid Surgery, China-Japan Union Hospital Of Jilin University, Jilin Provincial Key Laboratory Of Surgical Translational Medicine, Jilin Provincial Precision Medicine Laboratory of Molecular Biology and Translational Medicine on Differentiated Thyroid Carcinoma, 126 Xiantai Blvd, Changchun city, Jilin province, People's Republic of China.

Background: In this study, we aimed to compare the kinetics of intact parathyroid hormone (iPTH) during the perioperative period of endoscopic thyroidectomy via bilateral areola approach (ETBAA) in the same period, following a traditional open thyroidectomy approach (OTA).

Methods: We conducted a prospective observational study of patients who were undergoing thyroidectomy and level VI clearance. Patients who had been affected by papillary thyroid cancer (PTC) were stratified into three groups: those eligible for endoscopic treatment (ETBAA); patients who were eligible for ETBAA but had opted for OTA (OTA-L); and patients who were not suitable for endoscopic intervention (OTA-H). Read More

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http://dx.doi.org/10.1186/s12893-019-0656-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907128PMC
December 2019

Primary hyperparathyroid surgery under local anaesthesia: benefits of hypnosis.

Eur Arch Otorhinolaryngol 2020 Mar 5;277(3):887-892. Epub 2019 Dec 5.

Service ORL Et Chirugie Cervico-Faciale, Centre Hospitalo-Universitaire de Tours, 2 Boulevard Tonnellé, 37044, Tours, France.

Purpose: Minimally invasive parathyroid surgery and hypnosis are both increasing in prevalence. The objective of this study was to evaluate the efficacy of hypnoanalgesia compared with sedation during primary hyperparathyroid surgery under local anaesthesia.

Methods: All patients who underwent primary hyperparathyroid surgery under local anaesthesia in our department between January 2013 and April 2018 were included retrospectively in two groups: patients operated under hypnoanalgesia (HYP group), and patients operated under sedation (LA group). Read More

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http://dx.doi.org/10.1007/s00405-019-05754-5DOI Listing

[Educational Video: Hemithyreoidectomy with Neuromonitoring of the Recurrent Laryngeal Nerve].

Zentralbl Chir 2019 Dec 19;144(6):525-529. Epub 2019 Nov 19.

Chirurgische Klinik, Universitätsklinikum Erlangen, Deutschland.

Introduction: The mean prevalence of thyroid nodules in adults is about 20% and increases with age. Most of the thyroid nodules are benign, and are rarely malignant. However, malignancy can often only be conclusively determined after resection. Read More

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http://dx.doi.org/10.1055/a-1024-4662DOI Listing
December 2019

Feasibility and safety of ultrasound-guided percutaneous microwave ablation for tertiary hyperparathyroidism.

Int J Hyperthermia 2019 ;36(1):1129-1136

Department of Ultrasound, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.

Tertiary hyperparathyroidism (THPT) is very common in hemodialysis patients with secondary hyperparathyroidism. However, a medical treatment is not indicated for THPT. To investigate the feasibility, safety and efficacy of microwave ablation (MWA) in treating THPT. Read More

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http://dx.doi.org/10.1080/02656736.2019.1684576DOI Listing

Robotic-assisted parathyroidectomy through lateral cervical approach: first results in Belgium.

Acta Chir Belg 2019 Nov 22:1-6. Epub 2019 Nov 22.

Department of Otorhinolaryngology, University Hospital Ghent, Ghent, Belgium.

A parathyroidectomy has been the treatment of choice for primary hyperparathyroidism. Especially the improved imaging techniques have led to minimally invasive techniques. Aim of this study was to evaluate our experience with robot-assisted parathyroidectomy through lateral cervical approach. Read More

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http://dx.doi.org/10.1080/00015458.2019.1693155DOI Listing
November 2019

Video-assisted neck surgery (VANS) using a gasless lifting procedure for thyroid and parathyroid diseases: "The VANS method from A to Z".

Surg Today 2019 Nov 14. Epub 2019 Nov 14.

Department of Surgery, Kanaji Hospital, 1-5-6 Nakazato Kita-ku, Tokyo, 114-0004, Japan.

Purpose: To describe and evaluate our video-assisted neck surgery (VANS) method for thyroid and parathyroid diseases.

Methods: We describe in detail the VANS method for enucleation, lobectomy, total (nearly total) thyroidectomy, and lymph node dissection for malignancy and Graves' disease. In collaboration with the Japan Society of Endoscopic Surgery (JSES), we evaluated several aspects of this method. Read More

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http://dx.doi.org/10.1007/s00595-019-01908-4DOI Listing
November 2019
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Thoracoscopic surgical case of an ectopic mediastinal parathyroid adenoma detected by chance: a case report.

BMC Surg 2019 Nov 14;19(1):171. Epub 2019 Nov 14.

Department of Thoracic Surgery, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan.

Background: Ectopic mediastinal parathyroid tumor (EMPT) is a rare cause of primary hyperparathyroidism (PHPT); it is difficult to resect using the cervical approach. We describe a case of using video-assisted thoracic surgery (VATS) for EMPT resection.

Case Presentation: A 67-year-old woman with a history of postoperative thyroid cancer had no symptoms. Read More

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http://dx.doi.org/10.1186/s12893-019-0641-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857287PMC
November 2019

Comparison between single-photon emission computed tomography/computed tomography and ultrasound in preoperative detection of parathyroid adenoma: retrospective review of an institutional experience.

Nucl Med Commun 2019 Dec;40(12):1211-1215

Department of Pathology, Ankara Numune Training and Research Hospital, University of Health Sciences, Ankara, Turkey.

Objective: The aim of this study was to evaluate the accuracy of technetium- 99m-methoxyisobutylisonitrile (Tc-MIBI) single-photon emission computed tomography/computed tomography (SPECT/CT) and ultrasound in preoperative localization of single parathyroid adenomas (PTAs) in patients with primary hyperparathyroidism (pHPT) who would be suitable for minimally invasive parathyroidectomy (MIP).

Methods: A retrospective study of 143 consecutive patients with biochemical evidence of hyperparathyroidism who underwent preoperative localization of parathyroid lesions using Tc-MIBI SPECT/CT and ultrasound, and proceeded to parathyroid surgery at our institution from January 2013 to January 2018. Of these, 125 had single adenomas and are the subject of this study. Read More

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http://dx.doi.org/10.1097/MNM.0000000000001104DOI Listing
December 2019

MicroRNA levels in bone and blood change during bisphosphonate and teriparatide therapy in an animal model of postmenopausal osteoporosis.

Bone 2020 Feb 1;131:115104. Epub 2019 Nov 1.

TAmiRNA GmbH, Leberstrasse 20, 1110 Vienna, Austria; Austrian Cluster for Tissue Regeneration, Austria. Electronic address:

MicroRNAs control the activity of a variety of genes that are pivotal to bone metabolism. Therefore, the clinical utility of miRNAs as biomarkers and drug targets for bone diseases certainly merits further investigation. This study describes the use of an animal model of postmenopausal osteoporosis to generate a comprehensive dataset on miRNA regulation in bone tissue and peripheral blood during bone loss and specifically anti-resorptive and osteo-anabolic treatment. Read More

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http://dx.doi.org/10.1016/j.bone.2019.115104DOI Listing
February 2020

Microvascular clamp technique as a reversible simulation of parathyroid gland excision.

Am J Surg 2020 06 25;219(6):943-946. Epub 2019 Sep 25.

University of New Mexico Hospital Department of Surgery, Division of Otolaryngology, USA.

Introduction: This study demonstrates the effectiveness of a microvascular clamp to simulate parathyroid adenoma excision with respect to intraoperative parathyroid hormone (ioPTH) changes in vivo.

Methods: Cases in which microvascular clamps were employed intraoperatively in conjunction with intraoperative parathyroid hormone(ioPTH) assays were reviewed. ioPTH values were recorded throughout these procedures to assess the efficacy and reversibility of tissue ischemia using microvascular clamps. Read More

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http://dx.doi.org/10.1016/j.amjsurg.2019.09.026DOI Listing

Focused Parathyroidectomy Using Accurate Preoperative Imaging and Intraoperative PTH: Tertiary Care Experience.

Indian J Endocrinol Metab 2019 May-Jun;23(3):347-352

Department of Endocrine Surgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

Introduction: The cure rate after focused parathyroidectomy (FP) is dependent upon two critical adjuncts- concordant preoperative imaging and intraoperative parathyroid hormone (PTH), a technique which can reliably determine whether any other hyperfunctioning gland or glands are still present after resection of the lesion shown by imaging. We wanted to see the cure rate of FP by using these two adjuncts. We also sought to discern whether utilizing the central lab rapid PTH assay will lead to wider acceptance of this FP with intraoperative PTH in resource-constrained countries. Read More

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http://dx.doi.org/10.4103/ijem.IJEM_20_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683698PMC
October 2019

Factors infuencing the sensitivity of ultrasound and gamma location of the parathyroid adenoma.

Cir Esp 2020 Jan 19;98(1):18-25. Epub 2019 Oct 19.

Servicio de Innovación y Desarrollo, Hospital Universitario de Fuenlabrada, Madrid, España.

Introduction: The treatment of choice for primary hyperparathyroidism (PHPT) when there is proper preoperative localization of the adenoma is minimally invasive parathyroidectomy. However, imaging techniques are not always able to provide the exact location. The objective is to identify potential factors that might influence the sensitivity and concordance of ultrasound (US) and 99mTc-methoxy-isonitrile parathyroid scintigraphy (MIBI-PS) and the actual location of the adenoma. Read More

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http://dx.doi.org/10.1016/j.ciresp.2019.09.002DOI Listing
January 2020
1 Read

Increasing trend of bilateral neck exploration in primary hyperparathyroidism.

Am J Surg 2020 03 3;219(3):466-470. Epub 2019 Oct 3.

NorthShore University HealthSystem, Department of Surgery, Evanston, IL, USA; University of Chicago, Department of Surgery, Chicago, IL, USA. Electronic address:

Background: Bilateral neck exploration was the standard operation for primary hyperparathyroidism. With improvements in preoperative localization and use of intraoperative PTH (ioPTH) monitoring, minimally invasive unilateral neck exploration has been widely adopted. This study evaluates the trend in parathyroidectomies for primary hyperparathyroidism. Read More

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http://dx.doi.org/10.1016/j.amjsurg.2019.09.039DOI Listing
March 2020
1 Read
2.291 Impact Factor

The role of narrow-band imaging in parathyroid surgery: a preliminary evaluation in five parathyroid adenoma cases.

J Laryngol Otol 2019 Oct 18:1-3. Epub 2019 Oct 18.

Thyroid and Parathyroid Surgery Service, Otolaryngology Unit, Department of Health Sciences, San Paolo Hospital, Università degli Studi di Milano, Milan, Italy.

Background: Narrow-band imaging uses selective haemoglobin light absorption to emphasise vascular visualisation and capillary networks.

Objective: This study aimed to evaluate the application of this technique to parathyroid surgery.

Method: This preliminary evaluation was carried out on five consecutive patients with single parathyroid adenoma being considered for minimally invasive video-assisted parathyroidectomy. Read More

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http://dx.doi.org/10.1017/S0022215119002160DOI Listing
October 2019
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Successful Modified Transoral Endoscopic Parathyroidectomy Vestibular Approach For Secondary Hyperparathyroidism With Ectopic Mediastinal Glands.

Surg Laparosc Endosc Percutan Tech 2019 Dec;29(6):e88-e93

Departments of Surgery.

Background: Transoral endoscopic parathyroidectomy vestibular approach for secondary hyperparathyroidism (SHPT) is controversial with regard to the time consumed, safety, and feasibility. We present our initial experience with modified transoral endoscopic parathyroidectomy vestibular approach (m-TOEPVA) procedure for SHPT using total parathyroidectomy with autotransplantation.

Materials And Methods: We retrospectively reviewed 10 patients with SHPT who underwent the m-TOEPVA procedure from December 2017 to April 2018 at our center. Read More

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http://dx.doi.org/10.1097/SLE.0000000000000727DOI Listing
December 2019
3 Reads

A faster parathyroidectomy: Techniques to shorten non-surgical operating room time.

Am J Otolaryngol 2019 Nov - Dec;40(6):102292. Epub 2019 Sep 10.

Department of Otolaryngology - Head and Neck Surgery, Henry Ford Health System, 2700 West Grand Boulevard, Detroit, MI 48202, United States of America. Electronic address:

Objective: To assess the capacity of different techniques to reduce non-operative times during parathyroid surgery. The impact of monitored anesthesia care (MAC) instead of general anesthesia, and the pre-operative placement of a second peripheral intravenous catheter (PIV) were analyzed.

Methods: A retrospective case series at an academic medical center was performed to study patients undergoing parathyroidectomy by a single surgeon between November 2013 and October 2016. Read More

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http://dx.doi.org/10.1016/j.amjoto.2019.102292DOI Listing
April 2020
2 Reads

MINIMALLY INVASIVE PARATHYROIDECTOMY FOR PRIMARY HYPERPARATHYROIDISM.

Acta Endocrinol (Buchar) 2019 Apr-Jun;15(2):182-186

Erkan Ozturk Breat and Thyroid Clinic, Ankara, Turkey.

Context: Primary hyperparathyroidism (PHPT), characterized by the inappropriate secretion of parathyroid hormone (PTH) with respect to the extracellular calcium concentration. Curative treatment of PHPT is surgery and bilateral neck exploration has been replaced by minimally invasive parathyroidectomy (MIP), with the advanced imaging technologies combined with radio-guided occult lesion localization (ROLL).

Objectives: The present study analyzes the MIP data from 45 patients who underwent surgery for parathyroid adenoma and debates if MIP is a feasible technique for the treatment of PHPT. Read More

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http://dx.doi.org/10.4183/aeb.2019.182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711633PMC
September 2019
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Minimally invasive parathyroid carcinoma-A missing entity between parathyroid adenoma and carcinoma: Scintigraphic and histological features.

Clin Endocrinol (Oxf) 2019 12 3;91(6):842-850. Epub 2019 Oct 3.

Department of Endocrinology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Purpose: Minimally invasive parathyroid carcinoma (MIPC) is clinically and biochemically comparable with parathyroid adenoma (PA) though histopathologically differ from PA. MIPC is an intermediate of PA and parathyroid carcinoma (PC). In literature, there is no definite criterion to diagnose MIPC. Read More

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http://dx.doi.org/10.1111/cen.14088DOI Listing
December 2019
2 Reads
3.457 Impact Factor

Comparison of ultrasound-guided percutaneous microwave ablation and parathyroidectomy for primary hyperparathyroidism.

Int J Hyperthermia 2019 ;36(1):835-840

Department of Interventional Ultrasound, Chinese PLA General Hospital , Beijing , China.

To compare the clinical efficacy of ultrasound-guided percutaneous microwave ablation (MWA) and parathyroidectomy for primary hyperparathyroidism. In an observational retrospective study, we compared the outcomes in patients with primary hyperparathyroidism who underwent ultrasound-guided MWA with the outcomes in those who underwent surgical resection (SR). The primary outcome was cure rate. Read More

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http://dx.doi.org/10.1080/02656736.2019.1645365DOI Listing
January 2020
1 Read