1,312 results match your criteria Minimally Invasive Surgery of the Parathyroid


Surgical treatment of severe osteoporosis including new concept of advanced severe osteoporosis.

Osteoporos Sarcopenia 2017 Dec 18;3(4):164-169. Epub 2017 Dec 18.

Division of Endocrinology and Metabolism, Department of Internal Medicine, Dongguk University Ilsan Hospital, Goyang, Korea.

Severe osteoporosis is classified as those with a bone mineral density (BMD) T-score of -2.5 or lower, and demonstrate one or more of osteoporotic, low-trauma, fragility fractures. According to the general principle of surgical approach, patients with severe osteoporosis require not only more thorough pre- and postoperative treatment plans, but improvements in surgical fixtures and techniques such as the concept of a locking plate to prevent bone deformity and maximizing the blood flow to the fracture site by using a minimally invasive plate osteosynthesis. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S24055255173020
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http://dx.doi.org/10.1016/j.afos.2017.11.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372822PMC
December 2017
1 Read

PRE-OPERATIVE LOCALIZATION OF PARATHYROID ADENOMA: PERFORMANCE OF 4D MRI PARATHYROID PROTOCOL.

Endocr Pract 2019 Jan 18. Epub 2019 Jan 18.

From: 1Department of Surgery, University of Arizona Medical Center.

Introduction: Accurate pre-operative image localization is critical in selection of minimally invasive parathyroidectomy (MIP) as a surgical treatment approach in patients with primary hyperparathyroidism (PHPT). Sestamibi scan, ultrasound, computed tomography and conventional magnetic resonance imaging (MRI) has varying accuracy in localizing parathyroid adenoma. Our group had previously shown that 4D MRI is more accurate than conventional imaging in identifying single adenomas. Read More

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http://dx.doi.org/10.4158/EP-2018-0424DOI Listing
January 2019
5 Reads

A Randomized, Controlled Trial Comparing White-Light with Near-Infrared Autofluorescence for Parathyroid Gland Identification during Total Thyroidectomy.

J Am Coll Surg 2019 Jan 30. Epub 2019 Jan 30.

Section of Minimally-Invasive Surgery, Department of General Surgery, Cleveland Clinic Florida, Weston, FL, USA.

Background: Parathyroid glands are difficult to identify during total thyroidectomies and accidental resection can lead to problematic post-operative hypocalcemia. Our main goals were to evaluate the effectiveness of using near-infrared light (NIRL) auto-fluorescence intra-operatively for parathyroid-gland identification; and to measure its impact on postoperative hypocalcemia incidence.

Study Design: Total thyroidectomies were performed on 170 patients with different thyroid pathologies, block-randomized (1:1) into 2 equal groups. Read More

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http://dx.doi.org/10.1016/j.jamcollsurg.2018.12.044DOI Listing
January 2019
1 Read

Targeted Minimally Invasive Parathyroidectomy for Ectopic Aortopulmonary Adenoma Under Gamma Probe Guidance.

Innovations (Phila) 2018 Nov/Dec;13(6):451-454

Department of Cardiovascular Surgery, Heart Center, Cebeci Hospitals, Ankara University School of Medicine, Ankara, Turkey.

We report a case of 53-year-old woman with the parathyroid adenoma (PA) located in the aortopulmonary window with an aberrant right subclavian artery. Her preoperative calcium level was 11.3 mg/dL (reference range = 8. Read More

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http://dx.doi.org/10.1097/IMI.0000000000000562DOI Listing
December 2018
2 Reads

Solitary Parathyroid Adenoma Localization in Technetium Tc99m Sestamibi SPECT and Multiphase Multidetector 4D CT.

AJNR Am J Neuroradiol 2019 Jan 6;40(1):142-149. Epub 2018 Dec 6.

Nuclear Medicine (H.H.C., F.C.W.), The University of Texas MD Anderson Cancer Center, Houston, Texas.

Background And Purpose: Minimally invasive parathyroid surgery relies critically on image guidance, but data comparing the efficacy of various imaging modalities are scarce. Our aim was to perform a blinded comparison of the localizing capability of technetium Tc99m sestamibi SPECT, multiphase multidetector 4D CT, and the combination of these 2 modalities (technetium Tc99m sestamibi SPECT + multiphase multidetector 4D CT).

Materials And Methods: We reviewed the records of 31 (6 men, 25 women; median age, 56 years) consecutive patients diagnosed with biochemically confirmed primary hyperparathyroidism between November 2009 and March 2010 who underwent preoperative technetium Tc99m sestamibi SPECT and multiphase multidetector 4D CT performed on the same scanner with pathologic confirmation by resection of a single parathyroid adenoma. Read More

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http://dx.doi.org/10.3174/ajnr.A5901DOI Listing
January 2019
2 Reads
3.589 Impact Factor

Robotic Resection of Ectopic Parathyroid Glands in the Superior Posterior Mediastinum.

J Laparoendosc Adv Surg Tech A 2018 Dec 11. Epub 2018 Dec 11.

Division of Thoracic Surgery, Department of Surgery, The Ohio State University Wexner Medical Center , Columbus, Ohio.

Background: Ectopic parathyroid glands can present in a challenging location in the superior posterior mediastinum.

Methods: Two patients with primary hyperparathyroidism were operated on for ectopic paraesophageal parathyroid glands in the superior posterior mediastinum. Sestamibi scan, computed tomography (CT) scan, and photon emission CT were used to identify the exact location of these glands. Read More

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http://dx.doi.org/10.1089/lap.2018.0548DOI Listing
December 2018
2 Reads

Systematic review of cure and recurrence rates following minimally invasive parathyroidectomy.

BJS Open 2018 Dec 28;2(6):364-370. Epub 2018 May 28.

Department of Ear, Nose and Throat, Head and Neck Surgery St George's Hospital London UK.

Background: The majority of patients with primary hyperparathyroidism (PHPT) have a single overactive adenoma. Advances in preoperative imaging and surgical adjuncts have given rise to minimally invasive parathyroidectomy (MIP), with lower complication rates in comparison with bilateral neck exploration. Misdiagnosis and undertreatment of multiglandular disease, leading to potentially higher recurrence rates, remains a concern. Read More

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http://doi.wiley.com/10.1002/bjs5.77
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http://dx.doi.org/10.1002/bjs5.77DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254009PMC
December 2018
8 Reads

Validation of a novel method for localization of parathyroid adenomas using SPECT/CT.

J Otolaryngol Head Neck Surg 2018 Oct 26;47(1):65. Epub 2018 Oct 26.

Division of Otolaryngology-Head and Neck Surgery, University of Alberta, 1E4 Walter Mackenzie Center, 8440 112 Street, Edmonton, AB, T6G 2B7, Canada.

Background: Accurate localization of parathyroid adenomas is of critical importance in surgical planning for minimally invasive parathyroidectomy. SPECT/CT is considered the investigation of choice but has limitations regarding localization of superior versus inferior adenomas. We proposed a novel method for localization using SPECT/CT by determining the anterior-posterior relationship of the adenoma to a horizontal line in the coronal plane through the tracheoesophageal groove. Read More

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https://journalotohns.biomedcentral.com/articles/10.1186/s40
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http://dx.doi.org/10.1186/s40463-018-0307-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203983PMC
October 2018
3 Reads

Intraoperative parathyroid hormone testing in primary hyperparathyroidism surgery: time for giving up?

Eur Arch Otorhinolaryngol 2019 Jan 24;276(1):267-272. Epub 2018 Oct 24.

Thyroid and Parathyroid Surgery Service, Otolaryngology Unit, San Paolo Hospital, Department of Health Sciences, Università degli Studi di Milano, Milan, Italy.

Purpose: Intraoperative PTH testing (IOPTH) in treatment of primary hyperparathyroidism (PH) is debated. Some authors advise against IOPTH in patients with concordant preoperative imaging undergoing focused parathyroidectomy. This study aims to compare focused parathyroidectomy success rates with and without IOPTH in patients with concordant preoperative imaging. Read More

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http://dx.doi.org/10.1007/s00405-018-5179-xDOI Listing
January 2019
6 Reads

Impact of intraoperative parathyroid hormone monitoring on the management of patients with primary hyperparathyroidism.

Clin Endocrinol (Oxf) 2019 Feb 19;90(2):277-284. Epub 2018 Nov 19.

Centre for Endocrine Surgery, University College London Hospital & London Clinic, London, UK.

Background/objective: Intraoperative parathyroid hormone (IOPTH) monitoring during surgery for primary hyperparathyroidism (PHPT) could improve cure rate and simplify current care pathways. This study assesses the performance of US, MIBI and IOPTH monitoring and their impact on outcomes and perioperative strategy.

Design: This is a retrospective study of a prospectively maintained database of patients who underwent parathyroidectomy guided by preoperative US, MIBI and IOPTH monitoring. Read More

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http://doi.wiley.com/10.1111/cen.13882
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http://dx.doi.org/10.1111/cen.13882DOI Listing
February 2019
19 Reads

Transcervical resection of two parathyroid adenomas located on the anterior mediastinum.

Turk J Surg 2018 3;34(3):247-249. Epub 2018 Jan 3.

Department of Radiology, Yüzüncü Yıl University School of Medicine, Van, Turkey.

The mediastinum is a possible location of ectopic parathyroid adenoma. Most ectopic parathyroid glands in the mediastinum are found in the superior mediastinum within the thymus. In this article, two cases with ectopic mediastinal parathyroid adenomas that were excised via transcervical resection are presented. Read More

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https://www.turkjsurg.com/abstract/1535/eng
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http://dx.doi.org/10.5152/turkjsurg.2017.3270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173598PMC
January 2018
3 Reads

Combined ultrasound and Sestamibi scintigraphy provides accurate preoperative localisation for patients with primary hyperparathyroidism.

Ann R Coll Surg Engl 2019 Feb 5;101(2):97-102. Epub 2018 Oct 5.

General Surgery Department, Princess Royal University Hospital , Orpington , UK.

Introduction: Minimally invasive parathyroidectomy has advantages over the traditional bilateral neck exploration for the surgical treatment of primary hyperparathyroidism. It requires accurate localisation of the parathyroid pathology prior to surgery. The best method of preoperative localisation in a district general hospital setting is not well understood. Read More

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https://publishing.rcseng.ac.uk/doi/10.1308/rcsann.2018.0158
Publisher Site
http://dx.doi.org/10.1308/rcsann.2018.0158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351877PMC
February 2019
6 Reads

Feasibility of Intraoperative Neuromonitoring During Thyroid Surgery Using Transcartilage Surface Recording Electrodes.

Thyroid 2018 Nov;28(11):1508-1516

7 Department of Anesthesiology, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung Medical University Hospital, Faculty of Medicine, College of Medicine, Kaohsiung Medical University , Kaohsiung, Taiwan .

Background: Intraoperative neural monitoring (IONM) has gained widespread acceptance as an adjunct to the gold standard of visual identification of the recurrent laryngeal nerve (RLN) during thyroid surgery. Currently, laryngeal electromyography (EMG) recording during IONM is almost always performed using endotracheal tube (ETT) surface electrodes placed adjacent to vocal folds originating from the inner surface of the thyroid cartilage (TC). Therefore, it was hypothesized that surface recording electrodes placed on the outer surface of the TC should enable access to the EMG response of the vocal folds during IONM. Read More

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http://dx.doi.org/10.1089/thy.2017.0680DOI Listing
November 2018
21 Reads

SPECT-CT-guided ultrasound for parathyroid adenoma localisation - a one stop approach.

J Nucl Med Technol 2018 Aug 23. Epub 2018 Aug 23.

Royal Free London NHS Foundation Trust, United Kingdom.

To evaluate the accuracy of one-stop (single patient attendance) SPECT-CT-guided ultrasound (US) in the localisation of parathyroid adenomata (PTA). Secondary aims included analysing the effect of multiple PTA and concurrent thyroid disease on sensitivity. Patients with hyperparathyroidism that had undergone parathyroidectomy were identified over a 5 year period. Read More

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http://dx.doi.org/10.2967/jnmt.118.209767DOI Listing
August 2018
3 Reads

[Do We Have to Wait for the Result of the Intraoperative Quick Parathormone Test in Preoperative Localised Sporadic Parathyroid Adenoma?]

Zentralbl Chir 2018 Aug 22;143(4):367-372. Epub 2018 Aug 22.

Klinik für Visceral-, Thorax- und Gefäßchirurgie, Universitätsklinikum Gießen/Marburg, Marburg, Deutschland.

Background: In the recent years, targeted surgery, especially minimally invasive parathyroidectomy, has become the procedure of choice to treat sporadic primary hyperparathyroidism (pHPT) and is performed after preoperative standardised, accurate and reliable localisation. The intraoperative quick parathyroid hormone (qPTH) test is considered as a condition for successful resection of the parathyroid adenoma. The intraoperative qPTH test prolongs surgery and anaesthesia. Read More

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http://dx.doi.org/10.1055/a-0655-7791DOI Listing
August 2018
4 Reads

Does the Technique of Skin Closure Affect the Cosmesis of Cervical Thyroidectomy and Parathyroidectomy Scars? A Review of Literature.

Facial Plast Surg 2018 Oct 22;34(5):524-528. Epub 2018 Aug 22.

Department of Otolaryngology, University Hospital Lewisham, London, United Kingdom.

The cosmetic outcomes following thyroid and parathyroid surgery is a priority for patients as the surgical scar is in a visible area of the body. Although some have advocated the use of minimally invasive and robotic surgery, these are not without risks and it has been suggested that the scars are not necessarily more favorable. The three most common means of skin closure include the use of subcuticular sutures, clips, and tissue adhesive (with or without deeper subcutaneous sutures) and there are no previous reviews of the published evidence. Read More

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http://dx.doi.org/10.1055/s-0038-1660844DOI Listing
October 2018
15 Reads

Robot-Assisted Endocrine Surgery: Indications and Drawbacks.

J Laparoendosc Adv Surg Tech A 2019 Feb 22;29(2):129-135. Epub 2018 Aug 22.

2 Michael E. DeBakey Department of Surgery, Baylor College of Medicine , Houston, Texas.

Background: Over the last few decades, robotic surgery with the da Vinci system has become increasingly prevalent. Endocrine surgeons are witnessing a rapid growth in enthusiasm for robotic approaches for treating thyroid, parathyroid, and adrenal disease. For carefully selected patients, the robotic system may be the preferred technique, although its use remains controversial and indications are in evolution. Read More

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http://dx.doi.org/10.1089/lap.2018.0308DOI Listing
February 2019
4 Reads

miR-182-5p overexpression inhibits chondrogenesis by down-regulating PTHLH.

Cell Biol Int 2018 Aug 10. Epub 2018 Aug 10.

Department of Minimally Invasive Spine Surgery, The Second Affiliated Hospital of Inner Mongolia Medical University, NO 1, Yingfang Road, Hohhot, Inner Mongolia 010000, P. R. China.

Human bone marrow mesenchymal stem cells (hBM-MSC) have the ability of differentiating into chondrocytes and osteoblasts. miR-182-5p promotes osteoclastogenesis and bone metastasis by up-regulating the expression of parathyroid hormone-like hormone (PTHLH). However, the function of miR-182-5p in chondrogenesis is still unknown. Read More

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http://dx.doi.org/10.1002/cbin.11047DOI Listing
August 2018
3 Reads
1.930 Impact Factor

Five-year Retrospective Study on Primary Hyperparathyroidism in South India: Emerging Roles of Minimally Invasive Parathyroidectomy and Preoperative Localization with Methionine Positron Emission Tomography-Computed Tomography Scan.

Indian J Endocrinol Metab 2018 May-Jun;22(3):355-361

Division of Epidemiology and Biostatistics, St John's Research Institute, Bengaluru, Karnataka, India.

Background: Primary hyperparathyroidism (PHPT) is a common endocrine disease with a variable clinical presentation. PHPT is usually symptomatic at presentation in majority of the patients, especially in developing countries. As the accessibility to investigations, advanced imaging methods and surgical procedures are improving, the clinical profile of the patients with PHPT has undergone a palpable change compared to the earlier description. Read More

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http://dx.doi.org/10.4103/ijem.IJEM_445_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063170PMC
August 2018
8 Reads

Mediastinal Parathyroidectomy Using a Cervical Approach Under a Pneumomediastinum.

Semin Thorac Cardiovasc Surg 2018 Winter;30(4):472-474. Epub 2018 Jul 19.

Department of Thoracic, Endocrine Surgery and Oncology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.

Video-assisted thoracoscopic surgery (VATS) and robotic surgery are minimally invasive surgeries for mediastinal parathyroid adenomas. However, a transthoracic approach is often difficult in the cervicothoracic transition area because of the limited visual field. We report a novel minimally invasive surgery for an ectopic parathyroid adenoma in the middle mediastinum using a cervical approach under a pneumomediastinum. Read More

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http://dx.doi.org/10.1053/j.semtcvs.2018.07.007DOI Listing
January 2019
1 Read

Transcutaneous Recording During Intraoperative Neuromonitoring in Thyroid Surgery.

Thyroid 2018 Nov 24;28(11):1500-1507. Epub 2018 Aug 24.

2 Department of Faculty of Medicine, College of Medicine, and Kaohsiung Medical University , Kaohsiung, Taiwan .

Background: Recurrent laryngeal nerve (RLN) palsy remains a major source of morbidity after thyroid surgeries. Intraoperative neural monitoring (IONM) has gained increasing acceptance as an adjunct to standard practice of visual RLN identification. Endotracheal tube (ETT) surface recording electrodes systems are now widely used for IONM; however, a malpositioned ETT can cause false IONM results and requires time-consuming intraoperative verification of the ETT position and readjustment by the anesthesiologist. Read More

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http://dx.doi.org/10.1089/thy.2017.0679DOI Listing
November 2018
47 Reads

How I Do It: New Dissector Device Allows for Effective Operative Field in Transoral Endoscopic Thyroid Surgery Using Vestibular Approach.

Surg Innov 2018 Oct 19;25(5):444-449. Epub 2018 Jul 19.

1 Charité-Universitätsmedizin Berlin, Campus Charité Mitte/Campus Virchow-Klinikum, Berlin, Germany.

Background: Minimally invasive thyroid and parathyroid resections are rarely performed. Promising new endoscopic transoral approaches to the anterior neck (transoral endoscopic thyroidectomy vestibular approach [TOETVA]) have been described with good results and few complications. This study evaluates a new device to allow the safe entrance of trocars in the subplatysmal space for TOETVA in a cadaver model. Read More

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http://dx.doi.org/10.1177/1553350618785281DOI Listing
October 2018
5 Reads

Sonar guided focused parathyroidectomy under cervical block.

S Afr J Surg 2018 Jun;56(2):30-33

Department of Anesthesiology, Chris Hani Baragwanath Academic Hospital and the Faculty of Health sciences. University of the Witwatersrand, Johannesburg, South Africa.

Background: Presentation of hyperparathyroidism varies and is highly non-specific. The automated calcium analyzer has made the diagnosis easy. Similarly, the advent of Sestamibi scan has paved the way to minimally invasive parathyroidectomy indicated for parathyroid adenoma. Read More

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June 2018
3 Reads

Diagnostic accuracy of parathyroid hormone levels in washout samples of suspicious parathyroid adenomas: A single-centre retrospective cohort study.

Clin Endocrinol (Oxf) 2018 Oct 3;89(4):489-495. Epub 2018 Aug 3.

Department of Endocrinology and Metabolism, Ankara University School of Medicine, Ankara, Turkey.

Introduction: Minimally invasive surgery is an alternative surgical approach for primary hyperparathyroidism with less surgical trauma and anaesthesia complications. When combined with intraoperative measurement of parathyroid hormone (PTH), cure rates are exceeding 97%. Preoperative intact PTH determination in washout samples is really very useful when parathyroid lesions cannot be easily distinguished from thyroid lesions or sometimes lymph nodes. Read More

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http://dx.doi.org/10.1111/cen.13812DOI Listing
October 2018
21 Reads

Thoracoscopic approach in the treatment of ectopic thymic parathyroid adenoma.

Wideochir Inne Tech Maloinwazyjne 2018 Jun 7;13(2):270-277. Epub 2018 Feb 7.

Centre of Abdominal Surgery, Clinic of Gastroenterology, Nephrourology and Surgery, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.

Primary hyperparathyroidism is overproduction of parathyroid hormone, causing hypercalcemia. Parathyroid adenomas have been found to be the etiology for 80% of cases of primary hyperparathyroidism, while almost a quarter of them are ectopic. We present a case of ectopic thymic parathyroid adenoma, treated by the thoracoscopic approach. Read More

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http://dx.doi.org/10.5114/wiitm.2018.73331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041573PMC
June 2018
4 Reads

Value of I/Tc-sestamibi parathyroid scintigraphy with subtraction SPECT/CT in primary hyperparathyroidism for directing minimally invasive parathyroidectomy.

Am J Surg 2019 Jan 30;217(1):108-113. Epub 2018 Jun 30.

Department of Nuclear Medicine, La Timone University Hospital, Aix-Marseille University, France. Electronic address:

Background: Primary hyperparathyroidism/(PHPT) is one of the most common endocrinological conditions. Surgery remains the only curative option. We have evaluated the performance of double isotope I/Tc-sestamibi parathyroid scintigraphy/(PS) with subtraction SPECT/CT in PHP for identifying uniglandular disease. Read More

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http://dx.doi.org/10.1016/j.amjsurg.2018.06.027DOI Listing
January 2019
8 Reads

[Tips and technical issues for performing transoral endoscopic thyroidectomy with vestibular approach (TOETVA): a novel scarless technique for neck surgery].

Chirurg 2018 Jun 19. Epub 2018 Jun 19.

Chirurgische Klinik, Campus Charité Mitte | Campus Virchow-Klinikum, Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, Berlin, Deutschland.

Background: Nowadays, minimally invasive thyroid and parathyroid gland resections for both benign and malignant tumors are rarely performed. Recently, promising new endoscopic transoral approaches to the anterior neck have been described with good results and few complications. This study describes the first clinical series in Germany using transoral endoscopic thyroidectomy-vestibular approach (TOETVA) and identifies technical issues and solutions. Read More

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http://dx.doi.org/10.1007/s00104-018-0658-6DOI Listing
June 2018
21 Reads

The incidence of vocal fold motion impairment after primary thyroid and parathyroid surgery for a single high-volume academic surgeon determined by pre- and immediate post-operative fiberoptic laryngoscopy.

Int J Surg 2018 Aug 14;56:73-78. Epub 2018 Jun 14.

Division of Head and Neck Endocrine Surgery, Department of Otolaryngology - Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address:

Background: Vocal fold motion impairment (VFMI) is a well-recognized complication of thyroid and parathyroid surgery. Preoperative counseling requires a thorough understanding of the incidence, risk factors, and value of early diagnosis of postoperative VFMI. Our objective is to describe the incidence of and risk factors for VFMI for a single high-volume academic surgeon, and to assess the utility of immediate postoperative fiberoptic laryngoscopy (FOL) in early diagnosis of VFMI. Read More

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http://dx.doi.org/10.1016/j.ijsu.2018.06.014DOI Listing
August 2018
13 Reads

[Primary Hyperthyroidism. Minimally invasive video-assisted parathyroidectomy]

Rev Fac Cien Med Univ Nac Cordoba 2017 12 14;74(4):361-364. Epub 2017 Dec 14.

Hospital Nacional de Clínicas - FCM - UNC.

Objective: Show our experience performing the minimally invasive video-assisted parathyroidectomy with central approach for the treatment of patients with primary hyperparathyroidism without using intraoperative parathyroid hormone monitoring (IPTHM) based solely on the concordance of two preoperative localization studies.

Material And Methods: An informed consent for the accomplishment of a minimally invasive approach was performed on 27 selected patients diagnosed with primary hyperparathyroidism who underwent pre-operative cervical ultrasound and sesta-MIBI scintigraphy studies, which were consistent across them. None had a family history that might indicate a multiple endocrine neoplasia (MEN), known thyroid disease, previous neck incision, or suspicion of carcinoma. Read More

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http://dx.doi.org/10.31053/1853.0605.v74.n4.15594DOI Listing
December 2017
10 Reads

Highly specific preoperative selection of solitary parathyroid adenoma cases in primary hyperparathyroidism by quantitative image analysis of the early-phase Technetium-99m sestamibi scan.

J Med Imaging Radiat Oncol 2018 Oct 7;62(5):642-648. Epub 2018 Jun 7.

Department of Radiology, Lahey Hospital and Medical Center, Burlington, Massachusetts, USA.

Introduction: Highly specific preoperative localizing test is required to select patients for minimally invasive parathyroidectomy (MIP) in lieu of traditional four-gland exploration. We hypothesized that Tc-99m sestamibi scan interpretation incorporating numerical measurements on the degree of asymmetrical activity from bilateral thyroid beds can be useful in localizing single adenoma for MIP.

Methods: We devised a quantitative interpretation method for Tc-99m sestamibi scan based on the numerically graded asymmetrical activity on early phase. Read More

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http://dx.doi.org/10.1111/1754-9485.12753DOI Listing
October 2018
8 Reads

A rural perspective on minimally invasive parathyroidectomy: optimal preoperative imaging and patient outcomes.

ANZ J Surg 2019 Jan 5;89(1-2):43-47. Epub 2018 Jun 5.

Breast and Endocrine Surgical Unit, Department of Surgery, Wagga Wagga Rural Referral Hospital, Wagga Wagga, New South Wales, Australia.

Background: Our retrospective review of prospectively collected data evaluated the efficacy of minimally invasive parathyroidectomy (MIP) and compared preoperative imaging modalities in a rural referral centre.

Methods: Patients with a diagnosis of primary hyperparathyroidism underwent surgeon-performed ultrasound (SUS) and technetium-99 m sestamibi (MIBI). Radiologist-performed ultrasound (RUS) was sought when the diagnosis remained in doubt. Read More

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http://doi.wiley.com/10.1111/ans.14374
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http://dx.doi.org/10.1111/ans.14374DOI Listing
January 2019
12 Reads

Transoral Thyroid and Parathyroid Surgery Vestibular Approach: A Framework for Assessment and Safe Exploration.

Thyroid 2018 07 18;28(7):825-829. Epub 2018 Jun 18.

1 Division of Head and Neck Endocrine Surgery, Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins , Baltimore, Maryland.

The transoral endoscopic thyroidectomy vestibular approach (TOETVA) is a new approach to the central neck that avoids an anterior cervical incision. This approach can be performed with endoscopic or robotic assistance and offers access to the bilateral central neck. It has been completed safely in both North American and, even more extensively, international populations. Read More

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https://www.liebertpub.com/doi/10.1089/thy.2017.0642
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http://dx.doi.org/10.1089/thy.2017.0642DOI Listing
July 2018
36 Reads

Robotic Parathyroid Surgery: Current Perspectives and Future Considerations.

ORL J Otorhinolaryngol Relat Spec 2018 22;80(3-4):195-203. Epub 2018 May 22.

Department of Otorhinolaryngology and Head and Neck Surgery, St. Mary's Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom.

Robotic parathyroidectomy represents a novel surgical approach in the treatment of primary hyperparathyroidism when the parathyroid adenoma has been pre-operatively localised. It represents the "fourth generation" in the evolution of parathyroid surgery following a process of surgical evolution from cervicotomy and 4-gland exploration to a variety of minimally invasive, open and endoscopic, targeted approaches. The existing evidence (levels 2-3) supports it as a feasible and safe technique with equivalent results to targeted open parathyroidectomy for primary hyperparathyroidism in carefully selected patients. Read More

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http://dx.doi.org/10.1159/000488355DOI Listing
May 2018
4 Reads

Selective parathyroid venous sampling in primary hyperparathyroidism: A systematic review and meta-analysis.

Laryngoscope 2018 Nov 14;128(11):2662-2667. Epub 2018 May 14.

Division of Endocrine and Oncological Surgery, Department of Surgery, Tulane University School of Medicine, New Orleans, Louisiana.

Objective: Minimally invasive parathyroidectomy requires accurate preoperative localization techniques. There is considerable controversy about the effectiveness of selective parathyroid venous sampling (sPVS) in primary hyperparathyroidism (PHPT) patients. The aim of this meta-analysis is to examine the diagnostic accuracy of sPVS as a preoperative localization modality in PHPT. Read More

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http://dx.doi.org/10.1002/lary.27213DOI Listing
November 2018
7 Reads
2.032 Impact Factor

Applicability of transoral endoscopic parathyroidectomy through vestibular route for primary sporadic hyperparathyroidism: A South Indian experience.

J Minim Access Surg 2018 May 4. Epub 2018 May 4.

Department of Endocrine Surgery, Endocare Hospital, Vijayawada, Andhra Pradesh, India.

Introduction: Primary hyperparathyroidism is one of the most common endocrine disorders requiring surgical parathyroidectomy for its definitive treatment. Surgical exploration is traditionally performed through conventional open neck approach. A wide range of minimal access and minimally invasive endoscopic techniques (gas less and with gas) have been attempted in the past two decades. Read More

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http://www.journalofmas.com/preprintarticle.asp?id=231912
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http://dx.doi.org/10.4103/jmas.JMAS_264_17DOI Listing
May 2018
14 Reads

Diagnostic accuracy of 3T magnetic resonance imaging in the preoperative localisation of parathyroid adenomas: comparison with ultrasound and 99mTc-sestamibi scans.

Eur Radiol 2018 May 7. Epub 2018 May 7.

Department of Radiological Sciences, Oncology and Pathology, Sapienza University, viale Regina Elena 324, 00161, Rome, Italy.

Objectives: To evaluate the diagnostic performance of 3TMRI in comparison with ultrasound (US) and 99mTc-sestamibi scan for presurgical localisation of parathyroid adenomas (PTAs) in patients with primary hyperparathyroidism (PHPT).

Methods: Fifty-seven patients affected by PHPT were prospectively enrolled and underwent US, 99mTc-sestamibi and 3TMRI. T2-weighted and post-contrast T1-weighted Iterative decomposition of water and fat with Echo Asymmetry and Least squares estimation (IDEAL) sequences were acquired. Read More

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http://dx.doi.org/10.1007/s00330-018-5437-8DOI Listing
May 2018
22 Reads

Prophylactic thyroidectomy in children with multiple endocrine neoplasia type 2.

Br J Surg 2018 Sep 17;105(10):1319-1327. Epub 2018 Apr 17.

Division of Endocrine Surgery, University College Hospital and Great Ormond Street Hospital, London, UK.

Background: In patients with multiple endocrine neoplasia type 2 (MEN2) syndrome, genetic testing offers early diagnosis, stratifies the risk of developing medullary thyroid cancer (MTC) and informs the timing of thyroidectomy. The efficacy of treatment, which depends on timely and safe surgery, is not well established.

Methods: This was a retrospective review of diagnostic and clinicopathological outcomes of prophylactic thyroidectomy in children with MEN2 between 1995 and 2013 in the UK. Read More

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http://dx.doi.org/10.1002/bjs.10856DOI Listing
September 2018
8 Reads

Comparison of the Diagnostic Efficacy of Ultrasound-Guided Core Needle Biopsy With 18- Versus 20-Gauge Needles for Thyroid Nodules.

J Ultrasound Med 2018 Nov 25;37(11):2565-2574. Epub 2018 Mar 25.

Department of Pathology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea.

Objectives: To compare the diagnostic efficacy, complication rate, and core needle biopsy (CNB) specimen yield in 18- versus 20-gauge ultrasound (US)-guided CNB for diagnosis of thyroid nodules.

Methods: We included 81 consecutive thyroid nodules with US-guided biopsy by a 20-gauge core needle and 86 consecutive thyroid nodules with US-guided biopsy by an 18-gauge core needle during 2 years. The rate of inconclusive results, including nondiagnostic or atypia/follicular lesion of undetermined significance, was compared. Read More

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http://dx.doi.org/10.1002/jum.14614DOI Listing
November 2018
7 Reads

Ultrasound and the Evaluation of Pediatric Thyroid Malignancy: Current Recommendations for Diagnosis and Follow-up.

J Ultrasound Med 2018 Oct 25;37(10):2311-2324. Epub 2018 Mar 25.

Endocrine Surgery Center, Diabetes and Endocrinology Institute, Department of Surgery, University of Arizona, Phoenix School of Medicine, Banner University Medical Center, Phoenix, Arizona, USA.

Ultrasound (US) plays a critical role in the evaluation, treatment, screening, and surveillance of thyroid malignancy in pediatric patients. This review aims to summarize recent advances in this topic. Improvements in imaging technology have amplified the advantage of US and US-guided fine-needle aspiration biopsy for thyroid nodule evaluation, cancer diagnosis, and surgical planning. Read More

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http://dx.doi.org/10.1002/jum.14593DOI Listing
October 2018
4 Reads

Enhanced visualization of parathyroid glands during video-assisted neck surgery.

Langenbecks Arch Surg 2018 May 13;403(3):395-401. Epub 2018 Mar 13.

Klinik für Chirurgie und Zentrum für Minimal Invasive Chirurgie, Kliniken Essen-Mitte, Akademisches Lehrkrankenhaus der Universität Duisburg-Essen, Henricistrasse 92, 45136, Essen, Germany.

Purpose: Visualization and precise dissection of the parathyroid glands are a crucial step of thyroidectomy. Moreover, identification of parathyroid adenoma in patients with primary hyperparathyroidism can be challenging due to the possible abnormal location of the enlarged parathyroid. Near-infrared fluorescence (NIR) can be adopted during video-assisted neck surgery in addition to standard endoscopic magnification to enhance the visualization of the parathyroid tissue. Read More

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http://dx.doi.org/10.1007/s00423-018-1665-2DOI Listing
May 2018
1 Read

Additions of neural monitoring for thyroid surgery.

Endocrine 2018 09 24;61(3):547. Epub 2018 Feb 24.

Division for Endocrine and Minimally Invasive Surgery, Department of Human Pathology in Adulthood and Childhood "G. Barresi", University Hospital G. Martino, University of Messina, Via C. Valeria 1, 98125, Messina, Italy.

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http://dx.doi.org/10.1007/s12020-018-1565-9DOI Listing
September 2018
5 Reads

Maximum cosmesis for patients with primary hyperparathyroidism: a case for larger incisions.

J Surg Case Rep 2017 Oct 20;2017(10):rjx193. Epub 2017 Oct 20.

Division of Subspecialty General Surgery, Mayo Clinic College of Medicine, Rochester, MN, USA.

While minimally invasive parathyroidectomy is an advantage to many properly selected patients, longer incisions and even wide skin resection may be optimal in a select few. We present an 80-year-old woman with primary hyperparathyroidism and bothersome excess neck skin and subcutaneous fat. The parathyroid adenoma was easily excised through a vertically-oriented cervical excision that removed an ellipse of fat and skin. Read More

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http://dx.doi.org/10.1093/jscr/rjx193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798038PMC
October 2017
5 Reads

Pre-operative localization of abnormal parathyroid tissue by Tc-sestamibi in primary hyperparathyroidism using four-quadrant site analysis: an evaluation of the predictive value of vitamin D deficiency.

Endocrine 2018 04 5;60(1):36-45. Epub 2018 Feb 5.

Department of Medicine, Division of Endocrinology, College of Physicians & Surgeons, Columbia University, New York, NY, USA.

Context: Accurate preoperative localization of abnormal parathyroid tissue aids importantly in minimally invasive parathyroidectomy in patients with primary hyperparathyroidism. Vitamin D deficiency may possibly influence the success and characteristics of pre-operative localization because it is associated with more active disease and possibly larger adenomas. This could increase the sensitivity of the sestamibi to identify abnormal parathyroid tissue, but earlier reports are conflicting. Read More

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http://dx.doi.org/10.1007/s12020-018-1528-1DOI Listing
April 2018
30 Reads

[Laparoscopic Total Gastrectomy(LTG)in Patient with Multiple Gastric Neuroendocrine Tumor Related to Multiple Endocrine Neoplasia Type 1 - Two Case Reports].

Gan To Kagaku Ryoho 2017 Nov;44(12):1114-1116

Dept. of Gastroenterological Surgery, Saitama Cancer Center.

We herein report 2 cases of laparoscopic total gastrectomy(LTG)in patient with multiple gastric neuroendocrine tumor (NET)related to multiple endocrine neoplasia type 1(MEN1). Case 1: A 66-year-old female was diagnosed with multiple gastric NET. There was no finding of any other tumor, and parathyroid function was normal. Read More

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November 2017
8 Reads

Benefit of F-fluorocholine PET imaging in parathyroid surgery.

Eur Radiol 2018 Jun 25;28(6):2700-2707. Epub 2018 Jan 25.

Department of Nuclear Medicine, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.

Objectives: To assess the additional diagnostic value of F-fluorocholine PET imaging in preoperative localization of pathologic parathyroid glands in clinically manifest hyperparathyroidism in case of negative or conflicting ultrasound and scintigraphy results.

Methods: A retrospective, single-institution study of 26 patients diagnosed with hyperparathyroidism. In cases where ultrasound and scintigraphy failed to detect the location of an adenoma in order to allow a focused surgical approach, an additional F-fluorocholine PET scan was performed and its results were compared with the intraoperative findings. Read More

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http://dx.doi.org/10.1007/s00330-017-5190-4DOI Listing
June 2018
7 Reads

Evaluation Criteria and Surgical Technique for Transoral Access to the Thyroid Gland: Experimental Study.

J Invest Surg 2018 Jan 25:1-7. Epub 2018 Jan 25.

c Department of Gastrointestinal Surgery , Akershus University Hospital , Lørenskog , Norway.

Background: The development of endoscopic techniques motivated surgeons to search for alternative and more cosmetic approaches for thyroid and parathyroid surgery. Several variations of transoral access to the anterior neck areas were applied in recent years. One of them is a premandibular access proposed by Nakajo et al, it is performed through the oral vestibule by creating the working space by means of the lifting method. Read More

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http://dx.doi.org/10.1080/08941939.2018.1424271DOI Listing
January 2018
11 Reads

Niche point-of-care endocrine testing - Reviews of intraoperative parathyroid hormone and cortisol monitoring.

Crit Rev Clin Lab Sci 2018 03 22;55(2):115-128. Epub 2018 Jan 22.

b Laboratory Medicine and Pathology , Mayo Clinic , Rochester , MN , USA.

Point-of-care (POC) testing, which provides quick test results in near-patient settings with easy-to-use devices, has grown continually in recent decades. Among near-patient and on-site tests, rapid intraoperative and intra-procedural assays are used to quickly deliver critical information and thereby improve patient outcomes. Rapid intraoperative parathyroid hormone (ioPTH) monitoring measures postoperative reduction of parathyroid hormone (PTH) to predict surgical outcome in patients with primary hyperparathyroidism, and therefore contributes to the change of parathyroidectomy to a minimally invasive procedure. Read More

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http://dx.doi.org/10.1080/10408363.2018.1425975DOI Listing
March 2018
8 Reads

Nuclear Medicine Methods for Evaluation of Abnormal Parathyroid Glands in Patients with Primary and Secondary Hyperparathyroidism.

Folia Med (Plovdiv) 2017 12;59(4):396-404

Complex Oncology Center, Plovdiv, Bulgaria

Considered rare disease in the past, primary hyperparathyroidism (PHPT) has dramatically increased in incidence over the past thirty years with the introduction of routine calcium measurements; it is now approximately 42 per 100 000 persons. By far, the most common lesion found in patients with PHPT is the solitary parathyroid adenoma, occurring in 85%-90% of patients, while in the rest 10%- 15% primary hyperplasia of the parathyroid glands is present. Currently, the most widely used surgical approach is minimally invasive parathyroidectomy which is associated with less post-surgery complications and shorter operation time. Read More

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http://dx.doi.org/10.1515/folmed-2017-0054DOI Listing
December 2017
12 Reads

Lifestyle Intervention and Medical Management With vs Without Roux-en-Y Gastric Bypass and Control of Hemoglobin A1c, LDL Cholesterol, and Systolic Blood Pressure at 5 Years in the Diabetes Surgery Study.

JAMA 2018 01;319(3):266-278

Division of Endocrinology & Diabetes, Department of Medicine, University of Minnesota, Minneapolis.

Importance: The Roux-en-Y gastric bypass is effective in achieving established diabetes treatment targets, but durability is unknown.

Objective: To compare durability of Roux-en-Y gastric bypass added to intensive lifestyle and medical management in achieving diabetes control targets.

Design, Setting, And Participants: Observational follow-up of a randomized clinical trial at 4 sites in the United States and Taiwan, involving 120 participants who had a hemoglobin A1c (HbA1c) level of 8. Read More

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http://dx.doi.org/10.1001/jama.2017.20813DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833547PMC
January 2018
30 Reads