64,296 results match your criteria Mind & Brain The Journal of Psychiatry [Journal]


Mark Twain's life-long fascination with phrenology.

Authors:
Stanley Finger

J Hist Behav Sci 2019 Feb 20. Epub 2019 Feb 20.

Department of Psychological and Brain Sciences, and Program in History of Medicine, Washington University, St. Louis, Missouri.

Samuel Langhorne Clemens (Mark Twain; 1835-1910), American humorist and writer, followed scientific and medical developments, and relished exposing questionable practices and ideas. In his youth, he pondered how phrenologists were assessing character, and in 1855 he copied sections of a phrenology book and a skull diagram into a notebook. Later, in London, he had two phrenological examinations by Lorenzo Fowler-one without and the other after identifying himself. Read More

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http://dx.doi.org/10.1002/jhbs.21960DOI Listing
February 2019

[Lost objects: The territory of study and action of Psychiatry].

Authors:
Marcos Zurita

Vertex 2018 Sep;XXIX(141):374-378

Capítulo de Interconsulta y Psiquiatría de Enlace. Revista Atlas.

The aim of this paper is to discuss about some key issues concerning psychiatry. What really does a psychiatrist nowadays? What kind of disorder does he treat? Why psychiatry keeps itself apart from other specialties and within its own autonomous field? Having in mind the differences between the mental disorders, can we consider that the same semiological elements are appropriate for all of them or do we need to resume an individual analysis from each of those disorders? Can we go through the sparse spectrum of neurotic disorders ignoring the market forces or the dualistic interpretation? In this context, there is still room for questioning: is there an undiscovered explanation regarding the psychiatry disorders or are we trying to find a whole rationale explanation to study non-agroupable objects, lacking of that aforementioned common nuclear logic? And finally, could it be that the constant variables which we assume as the constitutive elements of psychiatric objects are barely the shifting boundaries that change as the time and the culture does? Read More

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September 2018

[Brain and mind: Dissidence or subordination? Notes for an epistemological reading].

Authors:
Juan C Fantin

Vertex 2018 Sep;XXIX(141):368-373

Departamento de Psiquiatría y Salud Mental, Facultad de Medicina (UBA).

Two opposing readings of significant authors - Eric Kandel and Hans Jonas - are examined in relation to the mind-brain problem. From there, the thesis is argued that the inadequacy of the critique of materialistic scientism reduces the theoretical and practical possibilities of both psychiatry and psychoanalysis. Read More

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September 2018

Are Impairments in Theory of Mind Specific to Borderline Personality Disorder?

J Pers Disord 2019 Feb 20:1-15. Epub 2019 Feb 20.

Institute for Clinical Medicine, University of Oslo.

Impaired theory of mind (ToM) is an assumed feature of borderline personality disorder (BPD). Yet, no studies have compared ToM abilities in patients with BPD, other personality disorders, and healthy controls, or investigated the relationship between ToM and severity of psychopathology and interpersonal problems. In this study, ToM was investigated by the Movie for the Assessment of Social Cognition. Read More

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http://dx.doi.org/10.1521/pedi_2019_33_417DOI Listing
February 2019

Outcomes of a Gratitude Practice in an Online Community of Caring.

J Altern Complement Med 2019 Feb 20. Epub 2019 Feb 20.

1 Earl E. Bakken Center for Spirituality & Healing, The University of Minnesota, Minneapolis, MN.

Objectives: CaringBridge (CB) is a web-based social network where people share information, enlist support, and access resources following a difficult diagnosis; it can also be used to disseminate supportive self-care tools, such as a gratitude practice, for its users. Gratitude practices are shown to reduce stress and fear, improve sleep, and increase positive emotions and overall well-being. The purpose of this article was to report the findings of a brief gratitude intervention delivered to CB users. Read More

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http://dx.doi.org/10.1089/acm.2018.0460DOI Listing
February 2019

Is isolated hand weakness associated with subtypes of stroke?

Ideggyogy Sz 2019 Jan;72(1-2):59-63

Rumeli University, İstanbul, Turkey.

Background And Purpose: Isolated hand weakness is an uncommon condition in stroke patients. It is frequently confused with peripheral nerve system (PNS) pathologies; misdiagnosis may delay identification of the etiology and treatment of stroke. Herein, we aimed to underline the necessity of keeping the diagnosis of stroke in mind in case of patients with isolated hand weakness and to assess the etiology of stroke. Read More

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http://dx.doi.org/10.18071/https://doi.org/10.18071/isz.72.0059DOI Listing
January 2019

Mapping meditative states and stages with electrophysiology: concepts, classifications, and methods.

Curr Opin Psychol 2019 Jan 23;28:211-217. Epub 2019 Jan 23.

Contemplative Neuroscience and Integrative Medicine (CNIM) Laboratory, Vanderbilt University, United States.

Exploration of human consciousness remains a final frontier within basic neuroscience; that is, how the finite biological structure and function of the brain give rise to the seemingly infinite expanse that encompasses the terrain of the mind. Contemporary mindfulness and other contemplative practices across historical and post-modern traditions involve systematic forms of mental training that allow a practitioner to develop the mind in very specific and quantifiable ways. While there has been some progress identifying specific electrophysiological markers of meditation, some fundamental questions remain to this scientific enquiry; (1) how to concisely classify discrete and developmentally specific 'mind states' of consciousness that are in line with the subtle complex phenomenology of experience so to yield ontological quantifications? (2) what measures best represent such classification/quantification systems? (3) can the present electrophysiological purview map developmentally specified mind states and stages to neurobiological substrates, based on extant contention (i. Read More

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http://dx.doi.org/10.1016/j.copsyc.2019.01.007DOI Listing
January 2019

Neuronal spiking activity highlights a gradient of epileptogenicity in human tuberous sclerosis lesions.

Clin Neurophysiol 2019 Jan 30;130(4):537-547. Epub 2019 Jan 30.

Centre de Recherche Cerveau et Cognition, Université de Toulouse, Université Paul Sabatier Toulouse, Toulouse F-31330, France; Centre National de la Recherche Scientifique, CerCo, UMR 5549, Toulouse F-31052, France.

Objective: The mechanisms underlying epileptogenicity in tuberous sclerosis complex (TSC) are poorly understood.

Methods: We analysed neuronal spiking activity (84 neurons), fast ripples (FRs), local field potentials and intracranial electroencephalogram during interictal epileptiform discharges (IEDs) in the tuber and perituber of a patient using novel hybrid electrodes equipped with tetrodes.

Results: IEDs were recorded in the tuber and perituber. Read More

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http://dx.doi.org/10.1016/j.clinph.2018.12.013DOI Listing
January 2019

A double-blind pilot dosing study of low field magnetic stimulation (LFMS) for treatment-resistant depression (TRD).

J Affect Disord 2019 Feb 14;249:286-293. Epub 2019 Feb 14.

Department of Psychiatry, Weill Cornell Medical College-New York Presbyterian Hospital, 525 East 68th Street, New York, NY 10065, USA; Institute of Geriatric Psychiatry, Weill Cornell Medical College-New York Presbyterian Hospital, 525 East 68th Street, New York, NY 10065, USA.

Background: Low field magnetic stimulation is a potentially rapid-acting treatment for depression with mood-enhancing effects in as little as one 20-min session. The most convincing data for LFMS has come from treating bipolar depression. We examined whether LFMS also has rapid mood-enhancing effects in treatment-resistant major depressive disorder, and whether these effects are dose-dependent. Read More

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http://dx.doi.org/10.1016/j.jad.2019.02.039DOI Listing
February 2019

Reinforcement Learning Recruits Somata and Apical Dendrites across Layers of Primary Sensory Cortex.

Cell Rep 2019 Feb;26(8):2000-2008.e2

Department of Neuroscience, Mortimer Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY 10027, USA; Kavli Institute for Brain Science, Columbia University, New York, NY 10027, USA. Electronic address:

The mammalian brain can form associations between behaviorally relevant stimuli in an animal's environment. While such learning is thought to primarily involve high-order association cortex, even primary sensory areas receive long-range connections carrying information that could contribute to high-level representations. Here, we imaged layer 1 apical dendrites in the barrel cortex of mice performing a whisker-based operant behavior. Read More

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http://dx.doi.org/10.1016/j.celrep.2019.01.093DOI Listing
February 2019

Patient expectations and experiences of remote monitoring for chronic diseases: Systematic review and thematic synthesis of qualitative studies.

Int J Med Inform 2019 Apr 29;124:78-85. Epub 2019 Jan 29.

Department of Medicine, University of Otago Christchurch, 8140, New Zealand; Department of Nephrology, Canterbury District Health Board, Christchurch, New Zealand.

Objectives: To describe the range of patients' beliefs, attitudes, expectations, and experiences of remote monitoring for chronic conditions across different healthcare contexts and populations.

Design: We searched MEDLINE, Embase, PsychINFO, and CINAHL, Google Scholar, and reference lists of related studies through to July 2017. Thematic synthesis was used to analyse the findings of the primary studies. Read More

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http://dx.doi.org/10.1016/j.ijmedinf.2019.01.013DOI Listing

Dietary intake of people with severe mental illness: systematic review and meta-analysis.

Br J Psychiatry 2019 Feb 20:1-9. Epub 2019 Feb 20.

Associate Professor in Nutrition and Dietetics,School of Health Sciences and Priority Research Centre for Physical Activity and Nutrition,University of Newcastle,Australia.

Background: Severe mental illness (SMI) is thought to be associated with lower diet quality and adverse eating behaviours contributing towards physical health disparities. A rigorous review of the studies looking at dietary intake in psychotic disorders and bipolar disorder is lacking.AimsTo conduct a systematic, comprehensive evaluation of the published research on dietary intake in psychotic disorders and bipolar disorder. Read More

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http://dx.doi.org/10.1192/bjp.2019.20DOI Listing
February 2019

Language Performance in Preschool-Aged Boys with Nonsyndromic Autism Spectrum Disorder or Fragile X Syndrome.

J Autism Dev Disord 2019 Feb 19. Epub 2019 Feb 19.

MIND Institute, University of California Davis, Sacramento, USA.

In the present study, language performance on standardized assessments (e.g., overall verbal performance, receptive and expressive vocabulary) and spontaneous language produced in play was compared between preschool-aged boys with autism spectrum disorder (ASD, n = 25) and boys with fragile X syndrome (FXS, n = 16). Read More

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http://dx.doi.org/10.1007/s10803-019-03919-zDOI Listing
February 2019

Ferroptosis in Neurons and Cancer Cells Is Similar But Differentially Regulated by Histone Deacetylase Inhibitors.

eNeuro 2019 Jan-Feb;6(1). Epub 2019 Feb 15.

Burke Neurological Institute, White Plains, New York 10605.

Ferroptotic death is a mechanism for tumor suppression by pharmacological inhibitors that target the X transporter (cystine/glutamate antiporter) in a host of non-CNS and CNS tumors. Inhibition of this transporter leads to reduction of cystine uptake, cyst(e)ine deprivation, subsequent depletion of the versatile antioxidant glutathione, and reactive lipid species-dependent death. Accordingly, pharmacological inhibitors of the X transporter can also induce neuronal cell death raising concerns about toxicity in the CNS and PNS if these agents are used for chemotherapy. Read More

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http://dx.doi.org/10.1523/ENEURO.0263-18.2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378329PMC
February 2019

Randomised controlled trial of the impact of haemodiafiltration on uraemic neuropathy: FINESSE study protocol.

BMJ Open 2019 Jan 15;9(1):e023736. Epub 2019 Jan 15.

Renal and Metabolic, The George Institute for Global Health, UNSW, Newtown, New South Wales, Australia.

Introduction: The majority of patients undergoing haemodialysis (HD) show evidence of uraemic neuropathy, a condition with no known disease-modifying treatments. The pathogenesis of uraemic neuropathy is poorly understood, but may be related to cumulative exposure to middle molecules or other solutes such as potassium. It is not known whether haemodiafiltration (HDF) reduces the progression of uraemic neuropathy. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-023736DOI Listing
January 2019

Prosocial behavior in aging: which factors can explain age-related differences in social-economic decision making?

Int Psychogeriatr 2019 Feb 20:1-11. Epub 2019 Feb 20.

Department of Brain and Behavioral Sciences,University of Pavia,Pavia,Italy.

ABSTRACTObjectives:Older adults tend to exhibit more prosocial behavior than younger adults. However, little research has focused on understanding the factors that may explain such differences in the social decision-making process. The first aim was to examine if, and to what degree, the content of social information about a recipient has an impact on young vs. Read More

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http://dx.doi.org/10.1017/S1041610219000061DOI Listing
February 2019

Predictions as a window into learning: Anticipatory fixation offsets carry more information about environmental statistics than reactive stimulus-responses.

J Vis 2019 Feb;19(2)

Center for Mind/Brain Sciences (CIMeC), The University of Trento, Trento, Italy.

A core question underlying neurobiological and computational models of behavior is how individuals learn environmental statistics and use them to make predictions. Most investigations of this issue have relied on reactive paradigms, in which inferences about predictive processes are derived by modeling responses to stimuli that vary in likelihood. Here we deployed a novel anticipatory oculomotor metric to determine how input statistics impact anticipatory behavior that is decoupled from target-driven-response. Read More

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http://dx.doi.org/10.1167/19.2.8DOI Listing
February 2019

Torsion of a uterine leiomyoma - a rare cause of hemoperitoneum; a case report and review of the literature.

Med Ultrason 2019 Feb;21(1):77-82

1st Department of Obstetrics and Gynecology, University of Medecine and Pharmacy "Iuliu Hatieganu", Cluj Napoca, Romania.

Uterine leiomyomas are common benign uterine tumors but by contrast, their acute complications are very rare. We present an unusual case of 38-year-old woman that came to the emergency department with acute abdominal pain. The ultrasound revealed hemoperitoneum, a uterus with two intramural fibroids and a tender inhomogeneous pelvic mass that seems to connect with the uterus. Read More

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http://dx.doi.org/10.11152/mu-1784DOI Listing
February 2019

Prenatal diagnosis of Fragile X syndrome: small meiotic recombination events at the FMR1 locus.

Prenat Diagn 2019 Feb 18. Epub 2019 Feb 18.

Service de Génétique, CHRU de Tours, UMR 1253, iBrain, Université de Tours, Inserm, Tours, France.

Objective: Fragile X syndrome (FXS), the most common inherited cause of intellectual disability, is caused by an expansion over 200 CGG repeats (full mutation) in the FMR1 gene. Intergenerational instability of an expanded FMR1 allele is linked to the carrier's gender (female), the CGG repeat size and the number of AGG interspersions within the CGG repeat, making genetic counseling a complex task. The objective of our work was to emphasize the importance of combining haplotype analysis with FMR1 linked markers and CGG repeat sizing for prenatal diagnosis (PND) of FXS. Read More

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http://dx.doi.org/10.1002/pd.5439DOI Listing
February 2019

The importance of adequate recognition of normal and dysplastic myelopoiesis for the diagnosis of myelodysplastic syndromes.

Histol Histopathol 2019 Feb 19:18093. Epub 2019 Feb 19.

Escola de Citologia Hematològica Soledad Woessner-Parc de Salut Mar. Laboratorio de Citología Hematológica. Patología. GRETNHE, IMIM Hospital del Mar Research Institute, Barcelona, Spain.

The diagnosis of myelodysplastic syndromes is based on the presence of cytopenias, dysplastic morphological features on peripheral blood (PB) and bone marrow (BM), cytogenetic abnormalities and requires to rule out other diseases resembling these conditions. Optical cytomorphology is the cornerstone of diagnosis of MDS. The recognition of cytological myelodysplasia has a crucial value in diagnosis and prognosis of MDS. Read More

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http://dx.doi.org/10.14670/HH-18-093DOI Listing
February 2019

Fluorescence Based Investigation of Temperature-Dependent Pb-Specific 8-17E DNAzyme Catalytic Sensor.

J Fluoresc 2019 Feb 18. Epub 2019 Feb 18.

Department of Chemistry, University of Sistan and Baluchestan, Zahedan, 98135-674, Iran.

The 8-17E DNAzyme is a temperature-dependent DNA metalloenzyme catalyzing RNA trans esterification in the presence of Pb metal ions. Labeling the stems of the substrate and DNAzyme with the Cy3 and Cy5 respectively, the considered DNAzyme was studied by the fluorescence spectroscopy. The temperature-dependent variability of the Pb-specific 8-17E DNAzyme catalytic sensor was investigated trough a number of successive temperature fluctuations from 4 to 25 °C to obtain information. Read More

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http://dx.doi.org/10.1007/s10895-019-02346-8DOI Listing
February 2019

[Psychogenesis: Central concept of the disciplines of the mind?]

Vertex 2018 May;XXIX(139):195-202

Universidad de Cambridge, Reino Unido.

To contemporary neuroscience the concept of psychogenesis and all psychogenetic explanations are nonsense. Work on psychogenesis undertaken by the Cambridge group disagrees with the concept of mental disorder proposed by neuroscientific reductionism because it: 1) offers too narrow a view of the concept of mental disorder; and 2) does not do justice to its cultural complexity as shown by epistemological, historical and clinical research. The study of psychogenesis will help with the understanding and ethical management of many mental disorders. Read More

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Daytime Central Thalamic Deep Brain Stimulation Modulates Sleep Dynamics in the Severely Injured Brain: Mechanistic Insights and a Novel Framework for Alpha-Delta Sleep Generation.

Front Neurol 2019 4;10:20. Epub 2019 Feb 4.

Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY, United States.

Loss of organized sleep electrophysiology is a characteristic finding following severe brain injury. The return of structured elements of sleep architecture has been associated with positive prognosis across injury etiologies, suggesting a role for sleep dynamics as biomarkers of wakeful neuronal circuit function. In a continuing study of one minimally conscious state patient studied over the course of ~8½ years, we sought to investigate whether changes in daytime brain activation induced by central thalamic deep brain stimulation (CT-DBS) influenced sleep electrophysiology. Read More

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http://dx.doi.org/10.3389/fneur.2019.00020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369150PMC
February 2019

Task-Dependent Differences in Operant Behaviors of Rats With Acute Exposure to High Ambient Temperature: A Potential Role of Hippocampal Dopamine Reuptake Transporters.

Front Behav Neurosci 2019 4;13:15. Epub 2019 Feb 4.

Institute of Neuroscience, National Cheng-Chi University, Taipei, Taiwan.

Behavioral or cognitive functions are known to be influenced by thermal stress from the change in ambient temperature (Ta). However, little is known about how increased Ta (i.e. Read More

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http://dx.doi.org/10.3389/fnbeh.2019.00015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369190PMC
February 2019

Changes in Functional Connectivity Following Treatment With Emotion Regulation Therapy.

Front Behav Neurosci 2019 4;13:10. Epub 2019 Feb 4.

Department of Counseling and Clinical Psychology, Teachers College, Columbia University, New York, NY, United States.

Emotion regulation therapy (ERT) is an efficacious treatment for distress disorders (i.e., depression and anxiety), predicated on a conceptual model wherein difficult to treat distress arises from intense emotionality (e. Read More

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http://dx.doi.org/10.3389/fnbeh.2019.00010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369363PMC
February 2019

Developmental aspects in cultural neuroscience.

Authors:
Joan Y Chiao

Dev Rev 2018 Dec 28;50(A):77-89. Epub 2018 Jun 28.

International Cultural Neuroscience Consortium.

Research in cultural neuroscience and development examines the processes and mechanisms underlying the interaction of cultural systems with environmental and biological systems with a life course approach. Culture interacts with environmental and biological factors to shape the mind, brain and behavior across stages of development. Theoretical and empirical approaches in cultural neuroscience investigate how culture influences psychological and neurobiological mechanisms during developmental periods. Read More

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http://dx.doi.org/10.1016/j.dr.2018.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377197PMC
December 2018
1 Read

Fertility Preferences and Cognition: Religiosity and Experimental Effects of Decision Context on College Women.

J Marriage Fam 2018 Apr 14;80(2):521-536. Epub 2017 Nov 14.

Rutgers University, Department of Sociology, Davison Hall, New Brunswick, NJ 08901,

Better models of culture and cognition may help researchers understand fertility and family formation. We examine cognition about fertility using an experimental survey design to investigate how fertility preferences of college women are affected by two prompts that bring to mind fertility-relevant factors: career aspirations and financial limitations. We test the effects of these prompts on fertility preferences and ask how effects vary with respondent religiosity, an aspect of social identity related to fertility preferences. Read More

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http://dx.doi.org/10.1111/jomf.12449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377249PMC

Long non-coding RNAs discriminate the stages and gene regulatory states of human humoral immune response.

Nat Commun 2019 Feb 18;10(1):821. Epub 2019 Feb 18.

Department of Medicine, Division of Hematology/Oncology, Weill Cornell Medicine, New York, NY, 10021, USA.

lncRNAs make up a majority of the human transcriptome and have key regulatory functions. Here we perform unbiased de novo annotation of transcripts expressed during the human humoral immune response to find 30% of the human genome transcribed during this process, yet 58% of these transcripts manifest striking differential expression, indicating an lncRNA phylogenetic relationship among cell types that is more robust than that of coding genes. We provide an atlas of lncRNAs in naive and GC B-cells that indicates their partition into ten functionally categories based on chromatin features, DNase hypersensitivity and transcription factor localization, defining lncRNAs classes such as enhancer-RNAs (eRNA), bivalent-lncRNAs, and CTCF-associated, among others. Read More

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http://dx.doi.org/10.1038/s41467-019-08679-zDOI Listing
February 2019

Author Correction: Child sexual offenders show prenatal and epigenetic alterations of the androgen system.

Transl Psychiatry 2019 Feb 18;9(1):95. Epub 2019 Feb 18.

Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.

The affiliations. Originally, Kolja Schilz was named last in the affiliations, implying that he is the senior author. This has been corrected; Kolja Schilz is now mentioned after Martin Walter in both the html and PDF versions of the article. Read More

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http://dx.doi.org/10.1038/s41398-019-0417-6DOI Listing
February 2019

Predictable and Unusual Adverse Effects of Immunosuppression in Pediatric Liver Transplant Patients.

Exp Clin Transplant 2019 Jan;17(Suppl 1):230-233

From the Department of Pediatric Gastroenterology,Gazi University Faculty of Medicine, Ankara, Turkey.

Objectives: Our aim was to determine potentially adverse effects of immunosuppressive protocols after liver transplantation in children.

Materials And Methods: The medical records of 60 children who underwent liver transplant retrospectively analyzed. Corticosteroid, tacrolimus, and mycophenolate mofetil were the primary immunosuppressive agents used in our center. Read More

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http://dx.doi.org/10.6002/ect.MESOT2018.P81DOI Listing
January 2019

A case study of feedback and cognitive assessment of a young adult inpatient with major depressive disorder.

Australas Psychiatry 2019 Feb 19:1039856219828125. Epub 2019 Feb 19.

Youth Mental Health Team, Brain and Mind Centre, University of Sydney, Camperdown, NSW and; Sunshine Coast Mind and Neuroscience Thompson Institute, University of the Sunshine Coast, Birtinya, QLD, Australia.

Objectives:: Neurocognitive assessment and feedback to a young adult inpatient.

Methods:: Computerised neurocognitive assessment and feedback.

Results:: A collaborative process of personalised intervention. Read More

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http://dx.doi.org/10.1177/1039856219828125DOI Listing
February 2019

Can working memory be non-conscious?

Neurosci Conscious 2016 Jan 5;2016(1):niv011. Epub 2016 Feb 5.

Visual Perception Laboratory, Department of Psychiatry and Psychotherapy, Charité-Universitätsmedizin, 10117 Berlin, Germany.

Working memory (WM) is closely linked to conscious awareness: In most conceptions of WM, the inputs to WM need to be conscious. The findings of some recent studies, however, have been taken to suggest that WM can indeed operate on non-conscious inputs. Here, we argue that these findings can easily be accommodated by conventional conceptions of non-conscious perception and conscious WM. Read More

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http://dx.doi.org/10.1093/nc/niv011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368269PMC
January 2016

Behavioral and electrophysiological evidence for fast emergence of visual consciousness.

Neurosci Conscious 2015 Jan 30;2015(1):niv004. Epub 2015 Jul 30.

Department of Psychology, University of Turku, 20014, Finland.

A fundamental unsettled dispute concerns how fast the brain generates subjective visual experiences. Both early visual cortical activation and later activity in fronto-parietal global neuronal workspace correlate with conscious vision, but resolving which of the correlates causally triggers conscious vision has proved a methodological impasse. We show that participants can report whether or not they consciously perceived a stimulus in just over 200 ms. Read More

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http://dx.doi.org/10.1093/nc/niv004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368270PMC
January 2015

Non-pharmacological therapies for depressive symptoms in breast cancer patients: Systematic review and meta-analysis of randomized clinical trials.

Breast 2019 Jan 31;44:135-143. Epub 2019 Jan 31.

DPH, Instituto Nacional de Salud Pública, Av. Universidad 655, Sta. Ma. Ahuacatitlán, C.P. 62100, Cuernavaca, Morelos, Mexico. Electronic address:

Objective: Depressive symptoms are common comorbidities among breast cancer (BC) patients. Non-pharmacological therapies (NPTs) such as exercise and psychotherapy may reduce depressive symptoms; however, the evidence is inconclusive. The objective of this study is to evaluate if NPTs reduce depressive symptoms among BC patients. Read More

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http://dx.doi.org/10.1016/j.breast.2019.01.006DOI Listing
January 2019

Revealing quinquennial anticancer journey of morpholine: A SAR based review.

Eur J Med Chem 2019 Feb 8;167:324-356. Epub 2019 Feb 8.

Drug Design & Medicinal Chemistry Lab, Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, 110062, India. Electronic address:

Morpholine, a six-membered heterocycle containing one nitrogen and one oxygen atom, is a moiety of great significance. It forms an important intermediate in many industrial and organic syntheses. Morpholine containing drugs are of high therapeutic value. Read More

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http://dx.doi.org/10.1016/j.ejmech.2019.02.015DOI Listing
February 2019

Plasma estradiol levels and antidepressant effects of omega-3 fatty acids in pregnant women.

Brain Behav Immun 2019 Feb 15. Epub 2019 Feb 15.

Department of Obstetrics and Gynecology, Tokyo Medical University, Tokyo, Japan; Division of Health Care Research, Center for Public Health Sciences, National Cancer Center Japan, Tokyo, Japan.

Background: Omega-3 polyunsaturated fatty acids (PUFAs) reduce depressive symptoms through an anti-inflammatory effect, and injection of both omega-3 PUFAs and estradiol (E2) induces antidepressant-like effects in rats by regulating the expression of inflammatory cytokines. The aims of this study were to examine the association of increased E2 during pregnancy with depressive symptoms and with inflammatory cytokines in women who were and were not supplemented with omega-3 PUFAs.

Methods: Pregnant women with Edinburgh Postnatal Depression Scale scores ≥ 9 were recruited at 12-24 weeks of gestation. Read More

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http://dx.doi.org/10.1016/j.bbi.2019.02.014DOI Listing
February 2019
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Neuropathological Diagnoses of Demented Hispanic, Black, and Non-Hispanic White Decedents Seen at an Alzheimer's Disease Center.

J Alzheimers Dis 2019 Feb 11. Epub 2019 Feb 11.

Department of Neurology, University of California, Davis, Sacramento, CA, USA.

Our nation is becoming increasingly diverse; however, few autopsy studies examine multiple ethnoracial groups, especially Hispanics. We examined differences in neuropathological diagnoses of 435 deceased participants with dementia from three ethnoracial groups (35 Black, 28 Hispanic, and 360 non-Hispanic White) evaluated at the University of California Davis Alzheimer's Disease Center. We used novel applications of bootstrap resampling and logistic regression standardization to project neuropathological diagnostic rates for non-Hispanic Whites to minority sample characteristics to improve inference of findings. Read More

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http://dx.doi.org/10.3233/JAD-180992DOI Listing
February 2019

Human consciousness is supported by dynamic complex patterns of brain signal coordination.

Sci Adv 2019 Feb 6;5(2):eaat7603. Epub 2019 Feb 6.

INSERM, U 1127, F-75013 Paris, France.

Adopting the framework of brain dynamics as a cornerstone of human consciousness, we determined whether dynamic signal coordination provides specific and generalizable patterns pertaining to conscious and unconscious states after brain damage. A dynamic pattern of coordinated and anticoordinated functional magnetic resonance imaging signals characterized healthy individuals and minimally conscious patients. The brains of unresponsive patients showed primarily a pattern of low interareal phase coherence mainly mediated by structural connectivity, and had smaller chances to transition between patterns. Read More

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http://dx.doi.org/10.1126/sciadv.aat7603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365115PMC
February 2019
1 Read

Construct validity and factor structure of sense of coherence (SoC-13) scale as a measure of resilience in Eritrean refugees living in Ethiopia.

Confl Health 2019 6;13. Epub 2019 Feb 6.

1Department of Psychiatry, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.

Background: There is a scarcity of adapted measures to study resilience and mental health of people in humanitarian settings in Africa. The aim of this study was to identify the factor structure and other psychometric properties of the Sense of Coherence (SoC-13) scale in Eritrean refugees living in Ethiopia.

Methods: In a cross-sectional survey, 562 adults were selected randomly from Eritrean refugees living in Mai Aini camp, Ethiopia. Read More

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http://dx.doi.org/10.1186/s13031-019-0185-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366046PMC
February 2019

Compassion Focused Approaches to Working With Distressing Voices.

Front Psychol 2019 1;10:152. Epub 2019 Feb 1.

Centre for Compassion Research and Training, University of Derby, Derby, United Kingdom.

This paper presents an outline of voice-hearing phenomenology in the context of evolutionary mechanisms for self- and social- monitoring. Special attention is given to evolved systems for monitoring dominant-subordinate social roles and relationships. These provide information relating to the interpersonal motivation of others, such as neutral, friendly or hostile, and thus the interpersonal threat, versus safe, social location. Read More

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http://dx.doi.org/10.3389/fpsyg.2019.00152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367219PMC
February 2019
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[Splenic Injury during Replacement of the Thoracoabdominal Aorta].

Kyobu Geka 2019 Feb;72(2):104-107

Division of Cardiovascular Surgery, Tohoku University, Sendai, Japan.

Extraperitoneal approach is commonly employed for thoracoabdominal aortic repair via Stoney incision. It is supposedly rare to encounter abdominal visceral bleeding during that procedure. However, the spleen may spontaneously adhere to the adjacent peritoneum, which could induce incidental injury to the spleen by its anterior mobilization during extraperitoneal approach. Read More

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February 2019

[Clinical Assessment of Fourteen Cases of Thoracic Endometriosis].

Kyobu Geka 2019 Feb;72(2):87-91

Division of Thoracic Surgery,Tohoku Medical and Pharmaceutical University, Sendai, Japan.

We retrospectively assessed the clinical and pathological features of 14 patients with thoracic endometriosis who were treated at our hospital from 2007 to 2017. Thirteen patients presented pneumothorax and 1 patient presented bloody sputum. All were treated surgically. Read More

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February 2019

Enactive social cognition: Diachronic constitution & coupled anticipation.

Conscious Cogn 2019 Feb 14;70:1-10. Epub 2019 Feb 14.

Department of Philosophy, Faculty of Law, Humanities and the Arts, University of Wollongong, Wollongong, Australia. Electronic address:

This paper targets the constitutive basis of social cognition. It begins by describing the traditional and still dominant cognitivist view. Cognitivism assumes internalism about the realisers of social cognition; thus, the embodied and embedded elements of intersubjective engagement are ruled out from playing anything but a basic causal role in an account of social cognition. Read More

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http://dx.doi.org/10.1016/j.concog.2019.02.001DOI Listing
February 2019

A coumarin-based colorimetric fluorescent probe for rapid response and highly sensitive detection of hydrogen sulfide in living cells.

Talanta 2019 May 26;197:122-129. Epub 2018 Dec 26.

State Key Laboratory of Applied Organic Chemistry, Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, PR China. Electronic address:

Hydrogen sulfide (HS) plays a vital role in numerous biological processes in living organisms. To better understand its functions, a fluorescent probe to fast and sensitively detect HS is imminently needed. Keep this in mind, we reasonably designed probe DHC for detecting HS based on α, β-unsaturated ethanoylcoumarin fluorophore. Read More

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http://dx.doi.org/10.1016/j.talanta.2018.12.081DOI Listing

Subthalamic and pallidal oscillatory activity in patients with Neurodegeneration with Brain Iron Accumulation type I (NBIA-I).

Clin Neurophysiol 2019 Jan 25;130(4):469-473. Epub 2019 Jan 25.

Department of Neurology, Charité - Universitätsmedizin Berlin, Germany; NeuroCure, ExzellenzCluster, Charité - Universitätsmedizin Berlin, Germany; Berlin School of Mind and Brain, Humboldt-Universität zu Berlin, Germany. Electronic address:

Objectives: Neurodegeneration with Brain Iron Accumulation type I (NBIA-I) is a rare hereditary neurodegenerative disorder with pallidal degeneration leading to disabling generalized dystonia and parkinsonism. Pallidal or subthalamic deep brain stimulation can partially alleviate motor symptoms. Disease-specific patterns of abnormally enhanced oscillatory neuronal activity recorded from the basal ganglia have been described in patients with movement disorders undergoing deep brain stimulation (DBS). Read More

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http://dx.doi.org/10.1016/j.clinph.2018.12.012DOI Listing
January 2019

Statistical learning of speech regularities can occur outside the focus of attention.

Cortex 2019 Jan 28;115:56-71. Epub 2019 Jan 28.

Northwestern University, Department of Psychology, Evanston, IL, USA. Electronic address:

Statistical learning, the process of extracting regularities from the environment, plays an essential role in many aspects of cognition, including speech segmentation and language acquisition. A key component of statistical learning in a linguistic context is the perceptual binding of adjacent individual units (e.g. Read More

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http://dx.doi.org/10.1016/j.cortex.2019.01.013DOI Listing
January 2019

Improving simulation performance through Self-Learning Methodology in Simulated Environments (MAES©).

Nurse Educ Today 2019 Feb 6;76:62-67. Epub 2019 Feb 6.

Nursing Department, Catholic University of Murcia (UCAM), Spain. Electronic address:

Background: One of the main challenges faced by nursing educator is using the best strategy for students to learn. In MAES© (Self-learning methodology in simulated environments), the students are guided by a facilitator, and perform their simulations in a knowledge-specific area in a self-directed learning manner.

Method: The performance by the students in the MAES© simulation was compared to traditional Simulation-based learning (SBL). Read More

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http://dx.doi.org/10.1016/j.nedt.2019.01.020DOI Listing
February 2019

FMRpolyG alters mitochondrial transcripts level and respiratory chain complex assembly in Fragile X associated tremor/ataxia syndrome [FXTAS].

Biochim Biophys Acta Mol Basis Dis 2019 Feb 13. Epub 2019 Feb 13.

Department of Biochemistry, Faculty of Science, The M.S. University of Baroda, Vadodara 390002, Gujarat, India. Electronic address:

Fragile X-associated tremor/ataxia syndrome (FXTAS) is an inherited neurodegenerative disorder caused by an expansion of 55 to 200 CGG repeats (premutation) in FMR1. These CGG repeats are Repeat Associated non-ATG (RAN) translated into a small and pathogenic protein, FMRpolyG. The cellular and molecular mechanisms of FMRpolyG toxicity are unclear. Read More

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http://dx.doi.org/10.1016/j.bbadis.2019.02.010DOI Listing
February 2019