13,868 results match your criteria Milroy Disease


Successful treatment of breast cancer-related breast lymphedema by lymphovenous anastomosis in a male patient.

Microsurgery 2019 Mar 19. Epub 2019 Mar 19.

International Lymphedema Center, Hiroshima University Hospital, Hiroshima, Japan.

Men, as well as women may develop breast lymphedema following breast cancer treatment. Microsurgically performed lymphovenous anastomosis (LVA), an effective treatment for lymphedema of the extremities, has also been successfully applied to breast lymphedema. Here we report the first case of breast lymphedema secondary to male breast cancer, treated with supermicrosurgical LVA. Read More

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http://dx.doi.org/10.1002/micr.30447DOI Listing

Sentinel lymph node mapping in endometrial and cervical cancer: a survey of practices and attitudes in gynecologic oncologists.

J Gynecol Oncol 2019 May;30(3):e35

Division of Gynecologic Oncology, Ob/Gyn & Women's Health Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.

Objective: To determine patterns among gynecologic oncologists in sentinel lymph node mapping (SLNM) for endometrial cancer (EC) and cervical cancer (CC).

Methods: A online survey assessing the practice of SLNM, including incidence, patterns of usage, and reasons for non-use was distributed to Society of Gynecologic Oncology candidate and full members in August 2017. Descriptive statistics and univariate analysis was performed. Read More

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http://dx.doi.org/10.3802/jgo.2019.30.e35DOI Listing

Elephantiasis and Directed Occupational Rehabilitation.

Case Rep Vasc Med 2019 11;2019:6486158. Epub 2019 Feb 11.

Medicine School in São José do Rio Preto (FAMERP) and Research Group in the Clínica Godoy, Sao Jose do Rio Preto, Brazil.

The aim of the present study was to demonstrate the cure of elephantiasis over a ten-year follow-up period and novel discoveries with directed occupational rehabilitation. A 66-year-old female patient with a history of bilateral lower limb lymphedema reported the aggravation of the condition over the years, reaching stage III (elephantiasis). The physical examination confirmed elephantiasis. Read More

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http://dx.doi.org/10.1155/2019/6486158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388341PMC
February 2019

The Application of Virtual Reality for Preoperative Planning of Lymphovenous Anastomosis in a Patient with a Complex Lymphatic Malformation.

J Clin Med 2019 Mar 15;8(3). Epub 2019 Mar 15.

Saitama Children's Medical Center, Department of Plastic and Reconstructive Surgery/Lymph Clinic, Saitama 330-8777, Japan.

The management of lymphatic malformations (LMs) is challenging, particularly for large and complex lesions involving anatomical structures in the adjacent tissue. While lymphovenous anastomosis (LVA) has been reported as an effective treatment for lymphedema, it has hardly been described as a treatment for LM. Virtual reality has the ability to visualize human structures in three dimensions and can be used for the preoperative planning of complex cases. Read More

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http://dx.doi.org/10.3390/jcm8030371DOI Listing

Intraoperatively Detected But Previously Indocyanine Green-Negative Lymphatic Vessels May Have Misprized Potentials and Should Not Be Neglected in Lymphaticovenous Bypass Surgery.

Ann Plast Surg 2019 Mar 13. Epub 2019 Mar 13.

Joseph M. Still Burn and Reconstructive Center, Jackson, MS.

Introduction: Identification of patent lymphatic vessels without fibrosis and with high flow is difficult but crucial in the preoperative planning of lymphaticovenous anastomosis (LVA). Lymphatic vessels on the operating field cannot always be visualized preoperatively because of the anatomical and physiological characteristics of lymphedema tissue. The purposes of this study were to demonstrate our clinical experience in identifying indocyanine green (ICG)-negative lymphatics intraoperatively and to emphasize the therapeutic potential of performing anastomoses with ICG-negative lymphatics. Read More

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http://dx.doi.org/10.1097/SAP.0000000000001781DOI Listing

Dorsal Wrist Placement for Vascularized Submental Lymph Node Transfer Significantly Improves Breast Cancer-Related Lymphedema.

Plast Reconstr Surg Glob Open 2019 Feb 20;7(2):e2149. Epub 2019 Feb 20.

Division of Reconstructive Microsurgery, Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Taoyuan, Taiwan.

Background: Vascularized submental lymph node flap transfer to the wrist is an effective treatment for breast cancer-related lymphedema. Dorsal placement was hypothesized to offer superior outcomes due to favorable venous drainage; however, the flap is more visible in this position compared with the volar side and was a cosmetic concern for patients. This study compared the treatment response of breast cancer-related lymphedema with the placement of vascularized submental lymph node flaps at the wrist, between dorsal and volar recipient sites. Read More

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http://dx.doi.org/10.1097/GOX.0000000000002149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416112PMC
February 2019

Effectiveness of Vascularized Lymph Node Transfer for Extremity Lymphedema Using Volumetric and Circumferential Differences.

Plast Reconstr Surg Glob Open 2019 Feb 13;7(2):e2003. Epub 2019 Feb 13.

Division of Reconstructive Microsurgery, Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Taoyuan, Taiwan.

Background: Circumferential difference of lymphedematous limbs at designated anatomic distances has been the primary mode for measuring lymphedematous extremities. Computed tomography (CT) imaging produces accurate, consistent, hygienic volume measurements and a direct limb representation. This study compares these 2 main modalities and assesses their correlation. Read More

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http://dx.doi.org/10.1097/GOX.0000000000002003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416128PMC
February 2019

A pilot study of lower extremity lymphedema, lower extremity function, and quality of life in women after minimally invasive endometrial cancer staging surgery.

Gynecol Oncol 2019 Mar 15. Epub 2019 Mar 15.

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Duke University, Durham, NC, United States of America; Duke Cancer Institute, Durham, NC, United States of America.

Objective: The primary aim of this study was to pilot the use of an objective measurement technique to prospectively evaluate the incidence of lower extremity lymphedema (LEL) after minimally invasive staging surgery for endometrial cancer. Secondary objectives included observation of changes in lower extremity function and quality of life in this patient population.

Methods: A prospective evaluation of LEL was performed in 97 women who underwent minimally invasive staging surgery for endometrial cancer using comparative circumferential volume measurements. Read More

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http://dx.doi.org/10.1016/j.ygyno.2019.02.021DOI Listing

Secondary breast angiosarcoma: A multicentre retrospective survey by the national Italian association of Breast Surgeons (ANISC).

Breast 2019 Mar 7;45:56-60. Epub 2019 Mar 7.

IEO, Milano, Italy.

Background: Breast angiosarcoma is a malignant mesenchymal neoplasm, which accounts for approximately 2% of all soft tissue sarcomas. Secondary breast angiosarcoma (SBA) may be related to chronic lymphedema after a mastectomy with lymph node dissection (Stewart Treves syndrome) and previous radiotherapy for complications from breast radiation treatment. It is a very rare condition; therefore, diagnosis and management are still a challenge. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09609776193003
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http://dx.doi.org/10.1016/j.breast.2019.02.011DOI Listing
March 2019
1 Read

Primary Care of Breast Cancer Survivors.

Am Fam Physician 2019 Mar;99(6):370-375

Saint Louis University School of Medicine, St. Louis, MO, USA.

With declining mortality rates, the number of breast cancer survivors is increasing. Ongoing care after breast cancer treatment is often provided by primary care physicians. This care includes surveillance for cancer recurrence with a history and physical examination every three to six months for the first three years after treatment, every six to 12 months for two more years, and annually thereafter. Read More

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March 2019
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Prioritization of genes involved in endothelial cell apoptosis by their implication in lymphedema using an analysis of associative gene networks with ANDSystem.

BMC Med Genomics 2019 Mar 13;12(Suppl 2):47. Epub 2019 Mar 13.

Laboratory of Computer-Assisted Proteomics, Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, Prospekt Lavrentyeva 10, Novosibirsk, 630090, Russia.

Background: Currently, more than 150 million people worldwide suffer from lymphedema. It is a chronic progressive disease characterized by high-protein edema of various parts of the body due to defects in lymphatic drainage. Molecular-genetic mechanisms of the disease are still poorly understood. Read More

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http://dx.doi.org/10.1186/s12920-019-0492-9DOI Listing
March 2019
1 Read

[The Swollen Leg in Vascular Medical Practice].

Dtsch Med Wochenschr 2019 Mar 14;144(6):398-410. Epub 2019 Mar 14.

In case of an acute leg swelling a deep leg vein thrombosis needs to be excluded. In order to do this, compression sonography and the D-dimer-test are applied in the framework of an established diagnostic algorithm. The ensuing therapy consists in anticoagulation and compression. Read More

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http://dx.doi.org/10.1055/a-0379-9997DOI Listing
March 2019
1 Read

The Effect of a Regimen of Antifungal Cream Use on Episodes of Acute Adenolymphangitis (ADL) among Lymphedema Patients: An Application Using Marginal Structural Models.

J Epidemiol Glob Health 2018 Dec;8(3-4):176-182

Parasitic Diseases Branch, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, 1600 Clifton Rd. NE, MS A-06, Atlanta, GA 30329-4027, United States.

Episodes of adenolymphangitis (ADL) are a recurrent clinical aspect of lymphatic filariasis (LF) and a risk factor for progression of lymphedema. Inter-digital entry lesions, often found on the web spaces between the toes of those suffering from lymphedema, have been shown to contribute to the occurrence of ADL episodes. Use of antifungal cream on lesions is often promoted as a critical component of lymphedema management. Read More

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http://dx.doi.org/10.2991/j.jegh.2017.10.009DOI Listing
December 2018
1 Read

Possible applications of normative lower to upper limb ratios of tissue dielectric constant to lower extremity edema.

Int Angiol 2019 Feb;38(1):70-75

College of Medical Sciences, Nova Southeastern University, Fort Lauderdale, FL, USA.

Background: Lower extremity edema occurs in many conditions including congestive heart failure, lymphedema, diabetes-related, kidney and liver disease, chronic venous insufficiency with venous hypertension. Clinical edema assessment methods are often subjective and variable. Our goals were to introduce a simple noninvasive measurement procedure potentially useful to characterize lower extremity edema by providing normative values from which edema thresholds might emerge. Read More

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http://dx.doi.org/10.23736/S0392-9590.18.04088-9DOI Listing
February 2019

Efficacy of a collagen-fibrin sealant patch (TachoSil®) as adjuvant treatment in the inguinofemoral lymphadenectomy for vulvar cancer: a double-blind randomized-controlled trial.

Arch Gynecol Obstet 2019 Mar 11. Epub 2019 Mar 11.

Department of Obstetrics and Gynecology, AOUI Verona, University of Verona, Piazzale A. Stefani 1, 37126, Verona, Italy.

Purpose: To evaluate the effect of a collagen-fibrin sealant patch (TachoSil®) in preventing postoperative complications after inguinofemoral lymphadenectomy for vulvar cancer.

Methods: Double-blind randomized-controlled trial on consecutive patients undergoing bilateral inguinofemoral lymphadenectomy for vulvar cancer. Intraoperatively, inguinofemoral areas were randomized: one was treated with TachoSil®, while the contralateral had standard closure without collagen-fibrin sealant patch. Read More

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http://dx.doi.org/10.1007/s00404-019-05113-zDOI Listing
March 2019
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Ultra High-frequency Ultrasonographic Imaging with 70 MHz Scanner for Visualization of the Lymphatic Vessels.

Plast Reconstr Surg Glob Open 2019 Jan 22;7(1):e2086. Epub 2019 Jan 22.

Department of Plastic and Reconstructive Surgery, Università Cattolica del "Sacro Cuore," University Hospital "A. Gemelli," Rome, Italy.

Background: Identification and localization of functional lymphatic vessels are important for lymphaticovenular anastomosis. Conventional high-frequency ultrasound (CHFUS) has been reported to be useful for them, but it has some disadvantages. In this article, we present new capabilities of ultra high-frequency ultrasound (UHFUS) for imaging of the lymphatic vessels, which may overcome the weakness of CHFUS. Read More

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http://dx.doi.org/10.1097/GOX.0000000000002086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382250PMC
January 2019
1 Read

Findings of lymphoscintigraphy and the severity of lymphedema according to the extent of axillary lymph node dissection.

Asian J Surg 2019 Mar 8. Epub 2019 Mar 8.

Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Daegu, Republic of Korea. Electronic address:

Background: Lymphedema of the upper extremity is a common disease in breast cancer patients following breast cancer operation accompanied by lymphadenectomy. However, clinically, there is a discrepancy between the extent of axillary lymph node dissection (ALND) and the severity of lymphedema. Therefore, we investigated the relationship between the severity of lymphedema following breast cancer operation, including ALND, and axillary lymph node findings on lymphoscintigraphy. Read More

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http://dx.doi.org/10.1016/j.asjsur.2019.02.003DOI Listing
March 2019
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Lymphedema Incidence After Axillary Lymph Node Dissection: Quantifying the Impact of Radiation and the Lymphatic Microsurgical Preventive Healing Approach.

Ann Plast Surg 2019 Apr;82(4S Suppl 3):S234-S241

Division of Surgical Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.

Background: Axillary surgery and radiotherapy are important aspects of breast cancer treatment associated with development of lymphedema. Studies demonstrate that Lymphatic Microsurgical Preventive Healing Approach (LYMPHA) may greatly reduce the incidence of lymphedema in high-risk groups. The objective of this study is to summarize the evidence relating lymphedema incidence to axillary lymph node dissection (ALND), regional lymph node radiation (RLNR) therapy, and LYMPHA. Read More

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http://dx.doi.org/10.1097/SAP.0000000000001864DOI Listing
April 2019
1 Read

The Impact of Taxane-based Chemotherapy on the Lymphatic System.

Ann Plast Surg 2019 Apr;82(4S Suppl 3):S173-S178

Department of Radiation Oncology, Edwin L. Steele Laboratory, Massachusetts General Hospital, Boston, MA.

Background: Breast cancer-related lymphedema affects 700,000 breast cancer survivors in the United States. Although taxane-based chemotherapy regimens are commonly used in the treatment of breast cancer, the impact of taxanes on the lymphatic system remains poorly understood. This study aims to examine the influence of taxane-based chemotherapy on lymphatic function in breast cancer patients. Read More

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http://dx.doi.org/10.1097/SAP.0000000000001884DOI Listing
April 2019
2 Reads

Applying Mental Model Methods to Characterize Understanding of Gene-Environment Influences: The Case of Podoconiosis in Ethiopia.

Crit Public Health 2019 6;29(1):84-99. Epub 2017 Dec 6.

Addis Ababa University, NBH1, 4killo King George VI Street, Addis Ababa, Ethiopia,

The rapid pace of genomic discovery has raised public expectation and concerns about the utility of new discoveries and their potential to exacerbate health disparities. Improving literacy concerning gene and environmental (GxE) contributors to disease is needed to avoid commonly observed deterministic misconceptions about genomics. Mental models approaches that incorporate community engagement processes could be used to inform GxE literacy-building interventions. Read More

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http://dx.doi.org/10.1080/09581596.2017.1409885DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405231PMC
December 2017

Diagnostic Significance of Fibrin Degradation Products and D-Dimer in Patients With Breast Cancer-Related Lymphedema.

Ann Rehabil Med 2019 Feb 28;43(1):81-86. Epub 2019 Feb 28.

Department of Physical Medicine and Rehabilitation, Kosin University Gospel Hospital, Busan, Korea.

Objective: To find out whether levels of fibrin degradation products (FDP) and D-dimer are increased in breast cancer-related lymphedema (BCRL) as in many vascular diseases. FDP and D-dimer have been used in blood tests to help differentiate deep vein thrombosis in the diagnosis of lymphedema. Levels of FDP and D-dimer are often elevated in patients with BCRL. Read More

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http://dx.doi.org/10.5535/arm.2019.43.1.81DOI Listing
February 2019
1 Read

Therapeutic value of selective lymphadenectomy in interval debulking surgery for stage IIIc and IV epithelial ovarian cancer.

Authors:
Nan Song Yunong Gao

Int J Gynecol Cancer 2019 Mar 7. Epub 2019 Mar 7.

Department of Gynecology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital & Institute, Beijing, China

Objective: The role of selective lymphadenectomy at the time of interval debulking surgery in patients with advanced ovarian cancer remains a topic of debate. This study aimed to evaluate the value of selective lymphadenectomy during interval debulking surgery in patients with radiologic evidence of lymph node metastasis at initial diagnosis that ultimately become negative on imaging after neoadjuvant chemotherapy.

Methods: A retrospective analysis including patients with stage IIIC-IV epithelial ovarian cancer and suspicious pelvic or para-aortic lymph node metastasis by imaging at diagnosis that resolved after neoadjuvant chemotherapy. Read More

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http://dx.doi.org/10.1136/ijgc-2018-000200DOI Listing
March 2019
1 Read

Frequency and risk factors for arm lymphedema after multimodal breast-conserving treatment of nodal positive breast Cancer - a long-term observation.

Radiat Oncol 2019 Mar 7;14(1):39. Epub 2019 Mar 7.

Department of Radiation Oncology, Hannover Medical School (MHH), Carl-Neuberg-Straße 1, 30625, Hannover, Germany.

Background: Arm-lymphedema is a major complication after breast cancer. Recent studies demonstrate the validity of predicting Breast Cancer Related Lymphedema (BCRL) by self-reports. We aimed to investigate the rate of BCRL and its risk factors in the long-term using self-reported symptoms. Read More

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https://ro-journal.biomedcentral.com/articles/10.1186/s13014
Publisher Site
http://dx.doi.org/10.1186/s13014-019-1243-yDOI Listing
March 2019
3 Reads

Patient recommendations for reducing long-lasting economic burden after breast cancer.

Cancer 2019 Mar 6. Epub 2019 Mar 6.

Department of Health Behavior and Society, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland.

Background: In the United States, patients who have breast cancer experience significant economic burden compared with those who have other types of cancers. Cancer-related economic burden is exacerbated by adverse treatment effects. Strategies to resolve the economic burden caused by breast cancer and its adverse treatment effects have stemmed from the perspectives of health care providers, oncology navigators, and other subject-matter experts. Read More

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http://dx.doi.org/10.1002/cncr.32012DOI Listing
March 2019
4 Reads

Supermicrosurgery training model for lymphaticovenous anastomosis in advanced lymphedema by iliolumbar vein and ureter anastomosis in the rat.

Microsurgery 2019 Mar 5. Epub 2019 Mar 5.

Chief of Plastic Surgery Department, Hospital Germans Trias i Pujol, Barcelona, Spain.

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http://dx.doi.org/10.1002/micr.30445DOI Listing
March 2019
1 Read

Diagnosing Male Unilateral Upper Limb Lymphedema: Determination of Normatively Determined Thresholds Using Bioimpedance Spectroscopy.

Lymphat Res Biol 2019 Mar 5. Epub 2019 Mar 5.

Discipline of Physiotherapy, Faculty of Health Sciences, The University of Sydney, Lidcombe, Australia.

Background: The use of bioimpedance spectroscopy (BIS) for the detection of unilateral upper limb lymphedema is growing. Currently, normatively determined diagnostic thresholds using bioimpedance are available for females only. It is unclear if they are suitable for males at risk of unilateral upper limb lymphedema. Read More

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http://dx.doi.org/10.1089/lrb.2018.0051DOI Listing
March 2019
1 Read

Chylous Manifestations and Management of Gorham-Stout Syndrome.

Korean J Thorac Cardiovasc Surg 2019 Feb 5;52(1):44-46. Epub 2019 Feb 5.

Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, University of Ulsan College of Medicine.

Gorham-Stout disease (GSD) was first described by Gorham and colleagues in 1954, but its precise mechanism and cause remain to be elucidated. In this condition, voluminous and potentially fatal chylous effusions into the thorax can occur. Herein, we describe a case of GSD in which the patient presented with massive pleural effusions and mottled osteolytic bone lesions. Read More

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http://dx.doi.org/10.5090/kjtcs.2019.52.1.44DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383852PMC
February 2019
1 Read

A comparative analysis of quality of life after postoperative intensity-modulated radiotherapy or three-dimensional conformal radiotherapy for cervical cancer.

Indian J Cancer 2018 Oct-Dec;55(4):327-335

Department of Radiation Oncology, Tata Memorial Hospital, Navi Mumbai, Maharashtra, India.

Aims: The aim of this study is to compare the quality of life (QOL) between adjuvant three-dimensional conformal radiotherapy (3DCRT) or intensity-modulated radiotherapy (IMRT) for cervical cancer.

Materials And Methods: QOL assessment was done at the baseline and then longitudinally after completing (chemo) radiation. All patients completed EORTC QLQ-C30 and EORTC QLQ Cx-24 modules. Read More

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http://dx.doi.org/10.4103/ijc.IJC_453_17DOI Listing
March 2019
3 Reads

Procedural Recommendations for Lymphoscintigraphy in the Diagnosis of Peripheral Lymphedema: the Genoa Protocol.

Nucl Med Mol Imaging 2019 Feb 7;53(1):47-56. Epub 2019 Jan 7.

Department of Surgery (DISC), Unit of Lymphatic Surgery & Microsurgery, Polyclinic Hospital 'San Martino', Genoa, Italy.

Introduction: Lymphoscintigraphy is the gold standard for imaging in the diagnosis of peripheral lymphedema. However, there are no clear guidelines to standardize usage across centers, and as such, large variability exists. The aim of this perspectives paper is to draw upon the knowledge and extensive experience of lymphoscintigraphy here in Genoa, Italy, from our center of excellence in the assessment and treatment of lymphatic disorders for over 30 years to provide general guidelines for nuclear medicine specialists. Read More

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http://dx.doi.org/10.1007/s13139-018-0565-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377575PMC
February 2019
1 Read

Postmastectomy upper limb lymphedema: Combined vascularized lymph node transfer and scar release with fat graft expedites surgical and patients' related outcomes. A retrospective comparative study.

J Plast Reconstr Aesthet Surg 2019 Feb 10. Epub 2019 Feb 10.

Division of Plastic and Reconstructive Surgery, Department of Emergency and Organ Transplantation, University of Bari, 11, Piazza Giulio Cesare, Bari 70124, Italy.

Introduction: Lymphedema resulting from breast cancer treatment is a chronic condition that can significantly compromise quality of life. Several works have documented the efficacy of vascularized lymph node flap transfer (VLNT) for the treatment of advanced-stage lymphedema. Given that the axillary scar may contribute to the patient's existing lymphedema, the authors assumed that combining VLNT and scar release with fat graft could be an effective strategy of treatment. Read More

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http://dx.doi.org/10.1016/j.bjps.2019.01.029DOI Listing
February 2019
3 Reads

Flow Pattern Classification in Lymphatic Malformations by Indocyanine Green Lymphography.

Plast Reconstr Surg 2019 Mar;143(3):558e-564e

Saitama and Tokyo, Japan From the Department of Plastic and Reconstructive Surgery, Saitama Children's Medical Center; the Lymph Clinic, Children's Medical Center; and the Department of Plastic and Reconstructive Surgery, University of Tokyo.

Background: Lymphatic malformation is a congenital lymphatic disorder. Although a few lymphangiographic and lymphoscintigraphic studies of lymphatic malformation exist, its lymphatic flow has not been fully assessed, and a classification system has not yet been established. However, indocyanine green lymphography has been developed to safely provide a fine assessment of lymph flow in the treatment of lymphedema. Read More

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http://dx.doi.org/10.1097/PRS.0000000000005362DOI Listing
March 2019
2 Reads

Do Groin Drains Reduce Postoperative Morbidity in Women Undergoing Inguinofemoral Lymphadenectomy for Vulvar Cancer?

Int J Gynecol Cancer 2018 01;28(1):183-187

King Edward Memorial Hospital, Subiaco.

Objective: Sentinel lymph node biopsy has been widely adopted in the surgical management of women with early-stage vulvar cancer, but many patients require inguinofemoral lymphadenectomy (IFL). Following IFL, many surgeons drain the groin to prevent lymphocyst formation despite a lack of evidence to support this practice. Our objective was to investigate whether groin drains after IFL are associated with reduced postoperative morbidity in women undergoing surgery for vulvar cancer. Read More

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http://dx.doi.org/10.1097/IGC.0000000000001146DOI Listing
January 2018
1 Read

Surgical Management of Pediatric Lymphedema: A Systematic Review.

J Reconstr Microsurg 2019 Feb 27. Epub 2019 Feb 27.

Division of Plastic Surgery, Albany Medical Center, Albany, New York.

Introduction:  Lymphedema is a rare, progressive, and debilitating condition caused by failure of the lymphatic system to adequately drain the protein-rich fluid exiting the capillaries. Conservative management is often emphasized in pediatric patients, resulting in a paucity of literature describing surgical treatment in this population.

Methods:  A systematic review was performed using PubMed, ScienceDirect, and Google Scholar to identify all studies describing surgical management of lymphedema in the pediatric population. Read More

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http://dx.doi.org/10.1055/s-0039-1681068DOI Listing
February 2019
6 Reads

Edema Fluid Can Be Successfully Evacuated from the Lymphedematous Limbs by Implantation of Silicone Tubings Bypassing the Site of Flow Obstruction Long-Term Observations.

Lymphat Res Biol 2019 Feb 27. Epub 2019 Feb 27.

3 Cardiovascular Clinic, Ahmedabad, India.

Background: Lymphedema of limbs is caused by partial or total obstruction of lymphatic collectors. In advanced cases all main lymphatics are obstructed and tissue fluid accumulates in the interstitial spaces. The microsurgical lympho-venous shunts cannot be performed. Read More

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http://dx.doi.org/10.1089/lrb.2018.0042DOI Listing
February 2019
1 Read

The 10-Min Holistic Self-Care for Patients with Breast Cancer-Related Lymphedema: Pilot Randomized Controlled Study.

Tohoku J Exp Med 2019 02;247(2):139-147

Department of Surgical Oncology, Tohoku University Graduate School of Medicine.

About 20% of patients with breast cancer are likely to develop breast cancer-related lymphedema (BCRL) following an axillary clearance, and BCRL can be refractory or irreversible to treatment. The aim of this pilot randomized controlled study was to evaluate the effectiveness of a 10-min holistic self-care program for patients with BCRL in Japan. The intervention group (n = 22) practiced the BCRL self-care program including 1) modified Japanese Radio Taiso (Rajio Taiso, national calisthenics in Japan), 2) gentle arm exercises combined with deep breathing, 3) central lymphatic drainage, and 4) skin care using a traditional lymphatic drainage technique daily for 6 months, while the control group (n = 21) received usual care from their hospitals. Read More

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http://dx.doi.org/10.1620/tjem.247.139DOI Listing
February 2019
1 Read

Multiple lymphatic-venous anastomoses in reducing the risk of lymphedema in melanoma patients undergoing complete lymph node dissection. A retrospective case-control study.

J Plast Reconstr Aesthet Surg 2019 Feb 10. Epub 2019 Feb 10.

Section of Plastic and Reconstructive Surgery, Department of Emergency and Organ Transplantation, University of Bari, 11, Piazza Giulio Cesare, Bari 70124, Italy.

Background: Sentinel lymph node biopsy (SLNB) is an indispensable surgical procedure in staging and management of intermediate-to-thick melanomas. Although recent studies have demonstrated that complete lymph node dissection (CLND) does not improve 3-year specific survival, its utility in increasing the disease-free period and the control of local disease remains confirmed. The most frequent complication related to CLND is lymphedema, which may affect up to 20% of patients undergoing CLND. Read More

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http://dx.doi.org/10.1016/j.bjps.2019.01.023DOI Listing
February 2019
1 Read

Does an Elastic Compression Bandage Provide Any Benefit After Primary TKA?

Clin Orthop Relat Res 2019 Jan;477(1):134-144

The Rothman Institute of Orthopedics at Thomas Jefferson University, Philadelphia, PA, USA.

Background: Compression bandages often are used after TKA to reduce swelling. However, the degree to which they are helpful has not been well characterized.

Questions/purposes: The purpose of this study was to determine whether use of a compression bandage after TKA was associated with (1) less leg swelling (our primary endpoint); or (2) secondary study endpoints, including improved ROM of flexion and extension, lower visual analog scale (VAS) pain scores for worst pain and pain during physical therapy just before surgery, postoperative day (POD) 1, POD 2, and POD 28, or fewer wound complications within 90 days of surgery. Read More

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http://dx.doi.org/10.1097/CORR.0000000000000459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345293PMC
January 2019
1 Read

Comparison of Staging Systems to Assess Lymphedema Caused by Cancer Therapies, Lymphatic Filariasis, and Podoconiosis.

Lymphat Res Biol 2019 Feb 21. Epub 2019 Feb 21.

Department of Tropical Disease Biology, Centre for Neglected Tropical Diseases, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.

Background: Lymphedema is a disease of the skin and subcutaneous tissue resulting from a disturbance in lymph flow. Anyone can be affected, and causes include cancer therapy when lymph nodes are removed or irradiated, the parasitic disease lymphatic filariasis, and damage caused by exposure to irritant soils known as podoconiosis. Manifest lymphedema is progressive and a major contributor to disability, stigma, and social isolation for affected people. Read More

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http://dx.doi.org/10.1089/lrb.2018.0063DOI Listing
February 2019
1 Read

Bariatric surgery and the evaluation of subclinical systemic lymphedema.

J Surg Case Rep 2019 Feb 8;2019(2):rjz028. Epub 2019 Feb 8.

Post-Graduate Strictu Sensu in Medicine School in São José do Rio Preto (FAMERP) and Research Group in the Clínica Godoy, Sao Jose do Rio Preto, Brazil.

The aim of the study was to report an improvement in clinical lymphedema in a patient who went from morbid obesity to overweight following bariatric surgery. A 52-year-old female patient reported having undergone bariatric surgery with a body mass index (BMI) of 51.2 kg/m, losing 40 kg and arriving at her current BMI of 37. Read More

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http://dx.doi.org/10.1093/jscr/rjz028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368206PMC
February 2019
1 Read

Lymphedema after Breast Cancer Treatment.

Authors:
Ayad Jindeel

N Engl J Med 2019 02;380(7):694

Essentia Health, Duluth, MN

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http://dx.doi.org/10.1056/NEJMc1817537DOI Listing
February 2019
6 Reads

Comparison of quantitative analysis to qualitative analysis for interpretation of lower-limb lymphoscintigraphy.

World J Nucl Med 2019 Jan-Mar;18(1):36-41

Department of Radiology and Nuclear Medicine, Aga Khan University Hospital, Nairobi, Kenya.

Qualitative analysis of lymphoscintigrams is subject to wide variability and may miss subtle differences in ilioinguinal uptake between normal and abnormal limbs. This study compared quantitative analysis to qualitative analysis of lower-limb lymphoscintigraphy in diagnosing lymphedema. Fifty-two lymphoscintigrams performed using standardized protocol, 99-metastable technetium nanocolloid intradermal injection at the first interdigital space, were analyzed quantitatively. Read More

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http://dx.doi.org/10.4103/wjnm.WJNM_17_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357716PMC
February 2019
1 Read

[General practitioner questionnaire concerning upper limb lymphedema after breast cancer].

Authors:
M Simon S Vignes

J Med Vasc 2019 Feb 20;44(1):3-8. Epub 2018 Dec 20.

Unité de Lymphologie, site constitutif du Centre national de référence des maladies vasculaires rares (lymphœdèmes primaires), hôpital Cognacq-Jay, 15, rue Eugène-Millon, 75015 Paris, France. Electronic address:

Introduction: In France, breast cancer is the most frequent cancer in women. Lymphedema, the main complication, is poorly known. The objective of this study was to assess the state of knowledge of upper limb lymphedema (risk factors, complications, treatment) after treatment of breast cancer among general practitioners from the Haute-Normandie and Île-de-France regions. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S25424513183017
Publisher Site
http://dx.doi.org/10.1016/j.jdmv.2018.11.004DOI Listing
February 2019
8 Reads

Post-traumatic lymphedema treatment with superficial circumflex iliac artery perforator lymphatic free flap: A case report.

Microsurgery 2019 Feb 15. Epub 2019 Feb 15.

Department of Plastic Surgery and Burns, Hospital del Trabajador, Santiago, Chile.

Post-traumatic lymphedema is poorly understood. It is rarely considered in limb reconstruction decision-making approach. We report a case of a 41-year-old female who presented with right upper extremity lymphedema after degloving injury and split thickness skin graft, successfully treated with a superficial circumflex iliac artery perforator (SCIP) free flap restoring the lymphatic drainage. Read More

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http://dx.doi.org/10.1002/micr.30437DOI Listing
February 2019
2 Reads

Lymphatic supermicrosurgery for the treatment of recurrent lymphocele and severe lymphorrhea.

Microsurgery 2019 Feb 14. Epub 2019 Feb 14.

International Lymphedema Center, Hiroshima University Hospital, Hiroshima, Japan.

Background: Lymphocele and lymphorrhea are frequent complications after lymph node excision. Recurrent lymphoceles and intractable lymphorrhea are particularly difficult to treat conservatively. We describe the outcomes of four patients with recurrent lymphocele and nine patients with persistent lymphorrhea that were treated by supermicrosurgery. Read More

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http://dx.doi.org/10.1002/micr.30435DOI Listing
February 2019
12 Reads

Lymphedema after Breast Cancer Treatment.

N Engl J Med 2019 02;380(7):694

Stanford University School of Medicine, Stanford, CA

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http://dx.doi.org/10.1056/NEJMc1817537DOI Listing
February 2019
1 Read

Modulation of Fibroblast Growth Factor Expression in Lymphedema.

Lymphat Res Biol 2019 Feb;17(1)

Stanford University School of Medicine, Stanford, California.

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http://dx.doi.org/10.1089/lrb.2019.29058.srDOI Listing
February 2019
1 Read

Management of vulvar lymphedema of filarial origin in a pregnant woman and its outcome: A case report.

J Obstet Gynaecol Res 2019 Feb 13. Epub 2019 Feb 13.

Department of Obstetrics and Gynaecology, Jawaharlal Nehru Institute of Post Graduate Education and Research, Pondicherry, India.

Lymphedema of filarial origin affecting the vulva is extremely rare. It is a dilemma if seen in a pregnant woman as there are no guidelines regarding excision and the mode of delivery. With the World Health Organization-driven global program to eradicate filaria, it is unfortunate to see such cases. Read More

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http://dx.doi.org/10.1111/jog.13933DOI Listing
February 2019
1 Read
0.931 Impact Factor

Intracellular Streptococcal Uptake and Persistence: A Potential Cause of Erysipelas Recurrence.

Front Med (Lausanne) 2019 29;6. Epub 2019 Jan 29.

Department of Dermatology, University Clinics, Ludwig-Maximilian University of Munich, Munich, Germany.

Erysipelas is a severe streptococcal infection of the skin primarily spreading through the lymphatic vessels. Penicillin is the treatment of choice. The most common complication consists in relapses which occur in up to 40% or more of patients despite appropriate antibiotic treatment. Read More

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https://www.frontiersin.org/article/10.3389/fmed.2019.00006/
Publisher Site
http://dx.doi.org/10.3389/fmed.2019.00006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361840PMC
January 2019
9 Reads

Modulation of Immunity by Lymphatic Dysfunction in Lymphedema.

Front Immunol 2019 29;10:76. Epub 2019 Jan 29.

Tumour Angiogenesis and Microenvironment Program, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.

The debilitating condition known as secondary lymphedema frequently occurs after lymphadenectomy and/or radiotherapy for the treatment of cancer. These therapies can damage lymphatic vessels leading to edema, fibrosis, inflammation and dysregulated adipogenesis, which result in profound swelling of an affected limb. Importantly, lymphedema patients often exhibit impaired immune function which predisposes them to a variety of infections. Read More

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http://dx.doi.org/10.3389/fimmu.2019.00076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361763PMC
January 2019
4 Reads