5,283 results match your criteria Miliary Tuberculosis
J Neurol Sci 2018 Dec 7;397:11-15. Epub 2018 Dec 7.
Department of Neurology, King George Medical University, Lucknow, Uttar Pradesh, India.
Objective: Computed tomography (CT) of the thorax is the imaging modality of choice to detect or demonstrate lesions suggestive of active pulmonary tuberculosis. We aimed to evaluate the imaging abnormalities detected on CT of the thorax in patients with tuberculous meningitis (TBM).
Methods: In this prospective study, we enrolled consecutive newly-diagnosed patients with TBM. Read More
Mol Clin Oncol 2018 Dec 1;9(6):673-676. Epub 2018 Oct 1.
Department of Respiratory Medicine, Kanagawa Cardiovascular and Respiratory Center, Yokohama, Kanagawa 236-0051, Japan.
Miliary lung metastases have been reported to be frequently observed in nοn-small cell lung cancer (NSCLC) with major EGFR mutations, which consist of exon 19 deletion and exon 21 L858R. However, it remains undetermined whether NSCLC with minor EGFR mutations possesses characteristics similar to those with major EGFR mutations. In the present study, two cases of miliary lung metastases from NSCLC with exon 20 insertion were reported. Read More
Intern Med 2018 Nov 19. Epub 2018 Nov 19.
Department of Respiratory Medicine, Fukuoka University Hospital, Japan.
We herein report a rare case of diffuse pulmonary metastasis occurring approximately one year after surgical excision of cutaneous squamous cell carcinoma that had been thought to be stage I with a free margin of healthy tissue. In addition, this case had chest imaging findings unusual for a skin cancer patient, showing a miliary pattern on computed tomography. Distant metastases may develop even if early-stage cutaneous squamous cell carcinoma is completely resected. Read More
Arch Dis Child Educ Pract Ed 2018 Nov 15. Epub 2018 Nov 15.
Department of Paediatric Neurology, Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates.
Differentiated thyroid cancer is a rare disease in children and adolescents and manifests exclusively in the form of papillary thyroid cancer (PTC). We present a rare case of PTC who presented initially with lung symptoms and miliary nodules on chest X-ray. This case emphasises the important differential of miliary mottling of the lungs. Read More
N Engl J Med 2018 Nov;379(20):1945
University of Colorado, Aurora, CO
Praxis (Bern 1994) 2018 Nov;107(23):1279-1282
3 Emergency Dpt, St Francis Referral Hospital and Ifakara Health Institute, Ifakara, Tanzania.
Point-of-Care Ultrasound: Teaching and Learning in Ifakara, Tanzania Abstract. Presentation of two practical cases from the point-of-care ultrasound class in Ifakara, Tanzania. The first case shows the sonographic findings of tuberculosis with findings in the lungs, heart, abdominal lymph nodes and spleen. Read More
Ann Diagn Pathol 2018 Oct 28;38:43-50. Epub 2018 Oct 28.
Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. Electronic address:
We present our experience with 75 cases of well-differentiated papillary mesothelioma (WDPM) that were diagnosed at our institution between 2000 and 2017. The patients included 58 females and 17 males with age ranging from 18 to 69 years (mean, 42 years). Clinically, the vast majority of WDPMs were incidental findings during laparotomy or laparoscopic surgery for a variety of benign or malignant disease. Read More
QJM 2018 Nov;111(11):819-820
Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Clin Microbiol Infect 2018 Oct 27. Epub 2018 Oct 27.
University of Groningen, Groningen Research Institute of Pharmacy, Unit of Pharmaco-Therapy, Epidemiology and -Economics (PTE2), the Netherlands.
Objectives: We evaluated treatment outcomes and predictors for poor treatment outcomes for tuberculosis (TB) among native- and foreign-born patients with drug-susceptible TB (DSTB) in the Netherlands.
Methods: This retrospective cohort study included adult patients with DSTB treated from 2005 to 2015 from a nationwide exhaustive registry. Predictors for unsuccessful treatment outcomes (default and failure) and TB-associated mortality were analysed using multivariate logistic regression. Read More
Int J Dermatol 2018 Nov 1. Epub 2018 Nov 1.
Department of Dermatology and Sexually Transmitted Diseases, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
J Clin Med 2018 Oct 29;7(11). Epub 2018 Oct 29.
Discipline of Paediatrics and Adolescent Medicine, The Children's Hospital at Westmead, The University of Sydney, Westmead 2145, Australia.
A 5-month-old boy presented with a focal seizure. Disseminated (miliary) tuberculosis (TB) was diagnosed on chest radiograph and TB meningitis was confirmed using Xpert MTB/RIF. The case represents the first instance of cerebrospinal fluid Xpert MTB/RIF testing in children in central Viet Nam. Read More
Radiol Bras 2018 Sep-Oct;51(5):313-321
Department of Radiology, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil.
Pulmonary fungal infections, which can be opportunistic or endemic, lead to considerable morbidity and mortality. Such infections have multiple clinical presentations and imaging patterns, overlapping with those of various other diseases, complicating the diagnostic approach. Given the immensity of Brazil, knowledge of the epidemiological context of pulmonary fungal infections in the various regions of the country is paramount when considering their differential diagnoses. Read More
Pan Afr Med J 2018 13;30:121. Epub 2018 Jun 13.
Katutura State Hospital, UNAM School of Medicine, Windhoek, Namibia.
Tuberculosis is still one of the most common respiratory diseases in Africa and worldwide and miliary tuberculosis is a regular manifestation of it. Idiopathic pulmonary hemosiderosis is a rare disease entity, presenting in children as well as adults. It is characterized by the triad of recurrent episodes of alveolar hemorrhage, presenting as hemoptysis, iron deficiency anemia and bilateral pulmonary infiltrates seen on chest X-ray. Read More
Expert Rev Anti Infect Ther 2018 Nov;16(11):813-831
a Department of Neurology , King George Medical University , Lucknow , India.
Introduction: Drug-resistant tuberculous meningitis has been reported worldwide. Isoniazid mono-resistance is the most frequent cause of drug-resistant tuberculous meningitis, a life-threatening disease. Extensive drug-resistant tuberculous meningitis has also been reported in some isolated case reports. Read More
Eur J Dermatol 2018 Aug;28(4):434-439
Dermatology Department, Hospital de Santo António dos Capuchos, Centro Hospitalar de Lisboa Central, Lisbon, Portugal.
Multiple miliary osteoma cutis consists of heterotopic foci of bone tissue in the dermis and subcutaneous tissue. Patients usually present with multiple, asymptomatic facial papules of several millimetres in diameter which cause distress regarding their cosmetic appearance. The condition is described as rare, as only a few cases have been reported since its first description in 1864 by Virchow. Read More
JMM Case Rep 2018 Aug 20;5(8):e005164. Epub 2018 Aug 20.
Department of Infectious Diseases, Nottingham University Hospitals City Campus, Nottingham NG5 1PB, UK.
Introduction: Guillain Barré Syndrome (GBS) has rarely been associated with tuberculosis and has been previously reported after Bacille Calmette Guérin (BCG) vaccination, but we report an association of GBS with intra-vesical BCG instillations followed by the clinical picture of disseminated BCGosis.
Case Presentation: A 68-year-old man with bladder carcinoma had a transurethral tumour resection followed by repeated BCG instillations. Catheterization for his eighth dose was traumatic, causing frank haematuria. Read More
Indian J Pathol Microbiol 2018 Oct-Dec;61(4):643
[This corrects the article DOI: 10.4103/IJPM.IJPM_126_17]. Read More
Respir Med Case Rep 2018 2;25:239-241. Epub 2018 Oct 2.
Penn Medicine-Princeton Medical Center Intensive Care Unit Department, 1 Plainsboro Road, Plainsboro, NJ 08536, USA.
Background: Disseminated tuberculosis (TB) or miliary TB is defined as lymphohematogenous dissemination of bacilli, which may then affect virtually any organ system. The multiple organ involvement in disseminated TB can mimic metastatic cancer and can make the diagnosis challenging. False negatives are common therefore repeating microbiologic and histologic samples is essential. Read More
Forensic Sci Med Pathol 2018 Oct 6. Epub 2018 Oct 6.
Forensic Unit, Department of Pathology, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, 56000, Kuala Lumpur, Malaysia.
Melioidosis is an infectious disease caused by Burkholderia pseudomallei, a gram-negative intracellular bacillus. Tuberculosis, also an infectious disease, is caused by Mycobacterium tuberculosis, an acid fast bacillus. In both diseases, patients commonly present with fever and respiratory symptoms due to sepsis which might lead to respiratory failure or sudden death if left untreated. Read More
BMJ Case Rep 2018 Oct 2;2018. Epub 2018 Oct 2.
Internal Medicine, Cooper University Hospital, Camden, New Jersey, USA.
The use of biologic drugs has expanded since its introduction in the late 1990s. With growing medical use and newer biologic drugs in development, opportunistic infections like remain important adverse effects. It carries major public health concerns, yet evidence-based clinical guidelines for more routine interval screening in patients taking immunosuppressants and exposed to tuberculosis (TB) are lacking. Read More
AME Case Rep 2018 17;2:36. Epub 2018 Jul 17.
Catholic Health System, Internal Medicine, University at Buffalo, NY, USA.
Dissemination of tuberculosis is known as miliary tuberculosis. The clinical features of disseminated tuberculosis often leads to misdiagnosis. By the time we have bone marrow involvement by tuberculosis, prognosis is really poor. Read More
Lancet 2018 09 24;392(10153):1096-1097. Epub 2018 Sep 24.
Division of Infection and Immunity, Centre for Clinical Microbiology, University College London, London, UK; National Institute of Health Research Biomedical Research Centre at UCL Hospitals, London, UK. Electronic address:
Anaesthesist 2018 Oct 26;67(10):773-779. Epub 2018 Sep 26.
Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Agaplesion Markus Krankenhaus, Wilhelm-Epstein-Str. 4, 60431, Frankfurt, Deutschland.
This article reports the fulminant course of a pneumogenic sepsis with severe ARDS (acute respiratory failure) in a 36-year-old female Indian patient, who died within 14 h after admission to the intensive care unit due to a multiorgan failure. During treatment the diagnosis of a miliary tuberculosis was suspected but was only confirmed by the autopsy. Due to high hygiene standards, miliary tuberculosis as the cause of septic shock is rare in Europe. Read More
Indian J Ophthalmol 2018 Oct;66(10):1496-1498
Department of Ophthalmology and Visual Science, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Republic of Korea.
A 30-year-old female presented with macular edema and discoid exudation at the posterior pole. Diffuse vascular sheathing was observed at the peripheral retina. Fluorescein angiography revealed multiple microaneurysms at the posterior pole and leakage from the peripheral vessels. Read More
Infez Med 2018 Sep;26(3):270-275
Internal Medicine Master of Medicine, Chiclayo, Lambayeque, Peru; Emergency Department of Regional Hospital of Lambayeque, Chiclayo, Lambayeque, Peru.
Central nervous system (CNS) tuberculosis includes three clinical entities: tuberculous meningitis, intracranial tuberculoma, and spinal tuberculous arachnoiditis. All three categories are encountered frequently in regions of the world where the incidence of TB is high. Meningeal tuberculosis is a medical emergency: it is the most severe, lethal and disabling form of tuberculosis. Read More
Infez Med 2018 Sep;26(3):255-262
Public Health and Infection Research Group, Faculty of Health Sciences, Universidad Tecnologica de Pereira, Pereira, Risaralda, Colombia;Committee on Tropical Medicine, Zoonoses and Travel Medicine, Asociación Colombiana de Infectología (ACIN), Bogotá, DC, Colombia; Medical School, Faculty of Health Sciences, UniFranz, Cochabamba, Bolivia.
Central nervous system (CNS) tuberculosis includes three clinical entities: tuberculous meningitis, intracranial tuberculoma, and spinal tuberculous arachnoiditis. All three categories are encountered frequently in regions of the world where the incidence of TB is high. Meningeal tuberculosis is a medical emergency: it is the most severe, lethal and disabling form of tuberculosis. Read More
Clin Rheumatol 2018 Sep 23. Epub 2018 Sep 23.
Department of Rheumatology, the First Affiliated Hospital of Sun Yat-sen University, No 58, Zhongshan Road 2, Guangzhou, 510080, Guangdong, China.
To investigate the characteristics and associated factors for Mycobacterium tuberculosis (TB) infection in patients with systemic lupus erythematosus (SLE) from Southern China. A retrospective study of 1108 patients admitted to the First Affiliated Hospital of Sun Yat-Sen University from January 2007 to December 2017 was performed. Demographic and clinical characteristics, laboratory data, and radiographic manifestations were recorded. Read More
CEN Case Rep 2018 Sep 22. Epub 2018 Sep 22.
Department of Pathology, Kitasato University School of Medicine, Sagamihara, Japan.
TAFRO syndrome (thrombocytopenia, anasarca, myelofibrosis, renal dysfunction, and organomegaly) is an atypical manifestation of multicentric Castleman's disease. Although overproduction of interleukin-6, vascular endothelial growth factor, and other cytokines may partially explain the pathophysiology of this rare syndrome, the precise mechanisms underlying the renal dysfunction associated with the condition remain unclear. Here, we describe a case of a 69-year-old male with TAFRO syndrome. Read More
Respir Med Case Rep 2018 11;25:216-219. Epub 2018 Sep 11.
Rheumatology Division, PSMMC, Riyadh, Saudi Arabia, P.O. Box 7897, Riyadh, 11159, Saudi Arabia.
A 26-year-old woman was diagnosed with and treated for systemic lupus erythematosus (SLE) in 2002. She was admitted 11 years later with nephrotic-range proteinuria and lupus nephritis and received two doses of rituximab after failing on steroids and mycophenolate mofetil. Four months later, she presented with fever and joint pain/swelling. Read More
Clin J Gastroenterol 2018 Sep 19. Epub 2018 Sep 19.
Department of gastroenterology, Peking University First Hospital, No. 7th, Xishiku Street, Xicheng District, Beijing, 100034, China.
A young patient had serious hematochezia for nearly 2 months without obvious cause. Abdominal CT images showed rare features such as serious hemorrhage and multiple miliary nodules in the small bowel. The colonoscopy showed multiple lymphoid follicles in the terminal ileum. Read More
J Cutan Aesthet Surg 2018 Apr-Jun;11(2):95-97
Department of Dermatology, Apollo Hospitals, Secunderabad, Telangana, India.
Multiple miliary osteoma cutis is an uncommon condition presenting as multiple skin-colored papules of variable sizes on the face. A 48-year-old woman presented with multiple skin-colored hard papules on both cheeks. Examination revealed firm-to-hard dome-shaped asymptomatic papules in cluster over both cheeks. Read More
Int J Mycobacteriol 2018 Jul-Sep;7(3):288-291
Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin General Hospital, Bandung, West Java, Indonesia.
Cutaneous tuberculosis (TB) has several clinical manifestations. The most common forms include cervical scrofuloderma and plaque type of lupus vulgaris (LV), otherwise the rare cases including inguinal scrofuloderma, ulcerative LV, and acute miliary TB. The highlight of this case series was to report various rare clinical manifestations of cutaneous TB. Read More
Pathogens 2018 Sep 5;7(3). Epub 2018 Sep 5.
School of Biomedical and Health Sciences, Universidad Europea de Madrid, 28670 Madrid, Spain.
An immunocompetent 82-year-old female was admitted to our hospital due to fever without clear origin and hyponatremia. In the following days, an acute and bilateral pulmonary infiltrate appeared with a progressive worsening in respiratory function. Chest x-ray and CT (Computed tomography) showed bilateral reticulonodular infiltrates. Read More
BMJ Case Rep 2018 Aug 31;2018. Epub 2018 Aug 31.
Department of Medicine, NewYork Presbyterian Hospital/Weill Cornell Medical Center, New York, NY, USA.
We describe the case of a 61-year-old man from the Dominican Republic admitted with diarrhoea, fevers and weight loss who was found to have lab studies and imaging (including radiolabeled somatostatin positron emission tomography/CT scan) initially consistent with a metastatic neuroendocrine tumour. However, after weeks of workup and multiple inconclusive biopsies, he was diagnosed with disseminated extrapulmonary tuberculosis. Here we examine the data for neuroendocrine tumour and tuberculosis labs and imaging to delineate where these studies overlap. Read More
Cureus 2018 Jun 18;10(6):e2831. Epub 2018 Jun 18.
Medicine, University of Arizona College of Medicine/mihs, Phoenix, USA.
() is a nontuberculous mycobacterium, which mainly infects the lungs in immunocompromised patients. We present here the case of a 27-year-old immunocompetent patient who developed pulmonary-renal syndrome, manifested with lung cavitation, miliary nodules, and necrotizing glomerulonephritis accompanied by elevated titers of myeloperoxidase antibody. Cultures from bronchoalveolar lavage were positive for , and the patient was treated with an anti-mycobacterial regimen. Read More
Front Pharmacol 2018 7;9:842. Epub 2018 Aug 7.
Institute of Clinical Biometrics, Center for Medical Statistics, Informatics, and Intelligent Systems, Medical University of Vienna, Vienna, Austria.
High-grade serous ovarian cancer (HGSOC) is considered the most deadly and frequently occurring type of ovarian cancer and is associated with various molecular compositions and growth patterns. Evaluating the mRNA expression pattern of the organic anion transporters (OATPs) encoded by genes may allow for improved stratification of HGSOC patients for targeted invention. The expression of mRNA and genes coding for putative functionally related ABC-efflux pumps, enzymes, pregnane-X-receptor, and (coding for estrogen receptors ERα and ERß) and HER-2 were assessed using RT-qPCR. Read More
Int J Paleopathol 2018 Aug 14. Epub 2018 Aug 14.
Department of Anthropology, State University of New York at New Paltz, USA.
In 1973, analysis of the mummified remains of a young boy dated to 700AD and from the Late Nasca period (Peru) identified (i) chronic Pott's disease, leading to loss of lower body mobility, and (ii) acute miliary tuberculosis, affecting most organs and the immediate cause of death (Allison et al., 1973). This report was the first to establish, beyond dispute, the presence of tuberculosis in the Americas before the arrival of Europeans. Read More
Int J Gynaecol Obstet 2018 Dec 29;143(3):387-388. Epub 2018 Aug 29.
Department of Internal Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
BMC Infect Dis 2018 Aug 10;18(1):390. Epub 2018 Aug 10.
Division of Pulmonary Medicine, the People's Hospital of Cangnan, Wenzhou Medical University, No.2288, Yucang Road, Cangnan County, Zhejiang, 325800, China.
Background: Talaromyces marneffei (T. marneffei) is a thermal dimorphic pathogenic fungus that often causes fatal opportunistic infections in human immunodeficiency virus (HIV)-infected patients. Although T. Read More
JAAD Case Rep 2018 Aug 1;4(7):648-650. Epub 2018 Aug 1.
NorthShore University, Department of Medicine Division of Dermatology, Skokie, Illinois.
Am J Respir Crit Care Med 2018 Nov;198(10):1334-1335
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Oman Med J 2018 Jul;33(4):352-355
Department of Internal Medicine, PGIMER, Chandigarh, India.
Tubercular splenic abscess is extremely rare, but are reported commonly in HIV-positive and immunocompromised patients along with miliary or disseminated tuberculosis. Isolated tubercular splenic abscess in an immunocompetent individual is rarely reported. Here we present a case of a young, immunocompetent male with isolated splenic cold abscesses, who was diagnosed with splenic tuberculosis and managed successfully with percutaneous drainage and anti-tubercular therapy alone. Read More
Zhonghua Xue Ye Xue Za Zhi 2018 Jun;39(6):521-522
Department of Hematology, Peking Union Medical College Hospital, CAMS & PUMC, Beijing 100730, China.
Med Mal Infect 2018 Dec 13;48(8):533-539. Epub 2018 Jul 13.
Maladies infectieuses et tropicales, hôpital Bichat, AP-HP, 46, rue Henri-Huchard, 75018 Paris, France; Inserm, IAME, UMR 1137, 16, rue Henri-Huchard, 75018 Paris, France; Université Paris-Diderot, IAME, UMR 1137, Sorbonne Paris Cité, 75018 Paris, France.
Background: Miliary tuberculosis (miliary TB) is characterized by a hematogenous spread of Mycobacterium tuberculosis. Cerebral lesions associated with miliary TB have been reported with diverse frequencies.
Methods: We retrospectively analyzed brain imaging in 34 patients presenting with proven miliary TB hospitalized in our teaching hospital between 2008 and 2014. Read More
Indian J Pathol Microbiol 2018 Jul-Sep;61(3):446-449
Department of Pathology, Adichunchanagiri Institute of Medical Sciences, Mandya, Karnataka, India.
Primary follicular lymphoma (PFL) of gastrointestinal tract (GIT) is rare and account for 1%-3% of non-Hodgkin lymphoma. Within the small intestine, the PFL is more common in jejunum than in the ileum. Due to low prevalence of the disease, the clinical manifestations are not well known, and diagnosis is usually delayed leading to complications. Read More
J Thorac Dis 2018 May;10(5):2881-2889
Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Background: After the introduction of chemotherapy, miliary tuberculosis (TB) has been more prevalent in adults than in children. However, adult patients have a wide age range and may have different characteristics across the age span. Thus, clinical manifestations and treatment outcome may differ according to age groups in adult patients with miliary TB. Read More
Int J Tuberc Lung Dis 2018 Aug;22(8):844-850
Service de Pneumologie et d'Allergologie Pédiatriques, Hôpital Universitaire Necker-Enfants Malades, Paris, France.
Objective: To evaluate inter-reader agreement and diagnostic accuracy of chest radiography (CXR) in the diagnosis of tuberculosis (TB) in children with human immunodeficiency virus (HIV) infection.
Design: HIV-infected children with clinically suspected TB were enrolled in a prospective study conducted in Burkina Faso, Cambodia, Cameroon and Viet Nam from April 2010 to December 2014. Three readers-a local radiologist, a paediatric pulmonologist and a paediatric radiologist-independently reviewed the CXRs. Read More
Med Mycol Case Rep 2018 Sep 6;21:1-3. Epub 2018 Mar 6.
Division of Infectious Diseases, Rush University Medical Center, Chicago, IL, USA.
This case report presents a 46-year old man with a failed liver transplant who presented with malaise and dyspnea. Imaging studies revealed diffuse reticulonodular infiltrates and innumerable miliary nodules and a left upper lobe consolidative mass. Examination of bronchoalveolar lavage fluid demonstrated yeast cells with broad-based budding. Read More
Small 2018 Jul 4:e1801022. Epub 2018 Jul 4.
Department of Obstetrics and Gynecology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, P. R. China.
Abdominal miliary spread and metastasis is one of the most aggressive features in advanced ovarian cancer patients. The current standard treatment of advanced ovarian cancer is cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC). However, most patients cannot receive optimal CRS outcomes due to the extreme difficulty of completely excising all microtumors during operation. Read More
Saudi J Kidney Dis Transpl 2018 May-Jun;29(3):719-722
Department of Internal Medicine, Keimyung University School of Medicine, Keimyung University Kidney Institution, Daegu, Korea.
A paradoxical reaction during anti-tuberculosis (anti-TB) therapy is commonly reported in patients with human immunodeficiency virus (HIV). However, a similar reaction to anti-TB therapy can also occur in patients without HIV, especially in patients who have undergone solid organ transplantation. A 65-year-old woman who underwent kidney transplantation six months prior presented to our emergency room with progressive paraparesis. Read More