673 results match your criteria Middle Ear Tympanic Membrane Infections


Automatic detection of tympanic membrane and middle ear infection from oto-endoscopic images via convolutional neural networks.

Neural Netw 2020 Jun 1;126:384-394. Epub 2020 Apr 1.

Department of Otorhinolaryngology-Head and Neck Surgery, Hallym University, Dongtan Sacred Heart Hospital, 7, Keunjaebong-gil, Hwaseong-si, Gyeonggi-do 18450, Republic of Korea. Electronic address:

Convolutional neural networks (CNNs), a popular type of deep neural network, have been actively applied to image recognition, object detection, object localization, semantic segmentation, and object instance segmentation. Accordingly, the applicability of deep learning to the analysis of medical images has increased. This paper presents a novel application of state-of-the-art CNN models, such as DenseNet, to the automatic detection of the tympanic membrane (TM) and middle ear (ME) infection. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neunet.2020.03.023DOI Listing

[Clinical features of occult mastoiditis complicated with periphlcbitis of sigmoid sinus in children].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2019 Dec;33(12):1158-1162

Department of Otolaryngology Head and Neck Surgery,National Center for Children's Health,Beijing Children's Hospital,Capital Medical University.

To investigate the clinical characteristics and principle of treatment of occult mastoiditis accompanied with periphlcbitis of sigmoid sinus in pediatrics. Four cases, with a short-time acute otitis media history, complained of headache / retroauricular pain, with papillary swelling, diagnosed as occult mastoiditis accompanied with periphlcbitis of sigmoid sinus according to the results of the temporal bone CT and MR. All of them had normal tympanic membrane, normal pure tone threshold, but type B tympanogram. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.13201/j.issn.1001-1781.2019.12.010DOI Listing
December 2019

Topical antiseptics for chronic suppurative otitis media.

Cochrane Database Syst Rev 2020 Jan 6;1:CD013055. Epub 2020 Jan 6.

Telethon Kids Institute, The University of Western Australia, 15 Hospital Avenue, Perth, Western Australia, Australia, 6009.

Background: Chronic suppurative otitis media (CSOM), sometimes referred to as chronic otitis media (COM), is a chronic inflammation and infection of the middle ear and mastoid cavity, characterised by ear discharge (otorrhoea) through a perforated tympanic membrane. The predominant symptoms of CSOM are ear discharge and hearing loss. Topical antiseptics, one of the possible treatments for CSOM, inhibit the micro-organisms that may be responsible for the infection. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/14651858.CD013055.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956662PMC
January 2020

Antibiotics versus topical antiseptics for chronic suppurative otitis media.

Cochrane Database Syst Rev 2020 01 6;1:CD013056. Epub 2020 Jan 6.

Telethon Kids Institute, The University of Western Australia, 15 Hospital Avenue, Perth, Western Australia, Australia, 6009.

Background: Chronic suppurative otitis media (CSOM), sometimes referred to as chronic otitis media (COM), is a chronic inflammation and infection of the middle ear and mastoid cavity, characterised by ear discharge (otorrhoea) through a perforated tympanic membrane. The predominant symptoms of CSOM are ear discharge and hearing loss. Antibiotics and antiseptics kill or inhibit the micro-organisms that may be responsible for the infection. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/14651858.CD013056.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956626PMC
January 2020

Topical antibiotics for chronic suppurative otitis media.

Cochrane Database Syst Rev 2020 01 2;1:CD013051. Epub 2020 Jan 2.

Brighton and Sussex University Hospitals NHS Trust, Department of Otolaryngology, Eastern Road, Brighton, UK, BN2 5BE.

Background: Chronic suppurative otitis media (CSOM), sometimes referred to as chronic otitis media (COM), is a chronic inflammation and often polymicrobial infection (involving more than one micro-organism) of the middle ear and mastoid cavity, characterised by ear discharge (otorrhoea) through a perforated tympanic membrane. The predominant symptoms of CSOM are ear discharge and hearing loss. Topical antibiotics, the most common treatment for CSOM, act to kill or inhibit the growth of micro-organisms that may be responsible for the infection. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/14651858.CD013051.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956124PMC
January 2020

Prevalence of Otitis Media with Effusion in Children with Hearing Loss.

Indian J Otolaryngol Head Neck Surg 2019 Nov 26;71(Suppl 2):1276-1281. Epub 2018 Mar 26.

Department of ENT, Guru Gobind Singh Medical College and Hospital, punjab, India.

Otitis media is an inflammation of the middle ear cleft, with or without intact tympanic membrane. Otitis media is known to be one of the most common childhood infections. Middle ear effusions have been recognized to grab increasing attention because of the problems they pose in both the diagnosis and the treatment, and because of the fear that effusion is the cause of learning difficulties, irreversible middle ear disease, or both. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12070-018-1310-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6841788PMC
November 2019

Functional assessment of moisture influenced cadaveric tympanic membrane using phase shift-resolved optical Doppler vibrography.

J Biophotonics 2020 Feb 19;13(2):e201900202. Epub 2019 Nov 19.

School of Electronics Engineering, College of IT Engineering, Kyungpook National University, Daegu, Republic of Korea.

An elevated relative moisture in the external ear canal and middle ear cavity may predispose to chronic otorrhea and related infections along with abnormal tympanic membrane (TM) vibration patterns. Therefore, phase shift-resolved optical Doppler vibrography (ODV) was used for vibration assessments of moisture influenced cadaveric TM. ODV was applied to generate time resolved cross-sectional and volumetric vibrographs of a cadaveric TM, driven acoustically at several frequencies. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jbio.201900202DOI Listing
February 2020

Pneumococcal serotype 19A is the major cause of pediatric acute otitis media with ruptured tympanic membrane in Addis Ababa, Ethiopia, 5 years after the introduction of the ten-valent pneumococcal conjugate vaccine.

Int J Pediatr Otorhinolaryngol 2019 Nov 13;126:109638. Epub 2019 Aug 13.

Laboratory Bacteriology Research, Department of Diagnostic Sciences, Faculty of Medicine & Health Sciences, Ghent University, Ghent, Belgium.

Introduction: In Ethiopia, there is a lack of data on pneumococcal serotypes causing acute otitis media (AOM) in children. We aimed to study the etiology, pneumococcal serotypes and antimicrobial resistance patterns of isolates from children with AOM with spontaneous perforation of the tympanic membrane (SPTM).

Methods: We carried out a prospective observational study in children with AOM with SPTM, aged 0-15 years in Addis Ababa, Ethiopia. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijporl.2019.109638DOI Listing
November 2019
1 Read

Age-Dependent Dissimilarity of the Nasopharyngeal and Middle Ear Microbiota in Children With Acute Otitis Media.

Front Genet 2019 19;10:555. Epub 2019 Jun 19.

Institute for Infectious Diseases, Faculty of Medicine, University of Bern, Bern, Switzerland.

Acute bacterial otitis media is usually caused by otopathogens ascending to the middle ear from the nasopharynx (NP). However, it is unknown if the nasopharyngeal microbiota of children with acute otitis media (AOM) can serve as an age-dependent or independent proxy for the microbial communities of the middle ear fluid (MEF) as there is a lack of 16S rRNA amplicon sequencing studies simultaneously analyzing the microbial communities of the two sites. Within this study, we performed 16S rRNA next generation sequencing on a total of 286 nasopharyngeal swabs (NPSs) collected between 2004 and 2013 within a Swiss national AOM surveillance program from children (0-6 years) with AOM. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fgene.2019.00555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593076PMC
June 2019
2 Reads

Long-term status of middle-ear aeration post canal wall down mastoidectomy.

J Laryngol Otol 2019 Aug 3;133(8):662-667. Epub 2019 Jul 3.

Otorhinolaryngology, Head and Neck Surgery, KPJ Tawakkal Specialist Hospital, Kuala Lumpur, Malaysia.

Background: Retraction pocket theory is the most acceptable theory for cholesteatoma formation. Canal wall down mastoidectomy is widely performed for cholesteatoma removal. Post-operatively, each patient with canal wall down mastoidectomy has an exteriorised mastoid cavity, exteriorised attic, neo-tympanic membrane and shallow neo-middle ear. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S0022215119001385DOI Listing
August 2019
3 Reads

Animal Model of Chronic Tympanic Membrane Perforation.

Anat Rec (Hoboken) 2020 Mar 16;303(3):619-625. Epub 2019 Jul 16.

Department of Otolaryngology, Head and Neck Surgery, University of Miami Miller School of Medicine, University of Miami Ear Institute, Miami, Florida.

Chronic tympanic membrane perforations (TMP) can be a source of significant morbidity from hearing loss, recurrent middle ear infections, changes in lifestyle, and risk of cholesteatoma formation. Laboratory experiments of TMP have been fraught by the rapid and high rate of spontaneous healing observed in animal models. There is controversy on the minimal time that perforations in animal models must have in order to be considered chronic TMP and thus have clinical relevance, with authors suggesting time periods of perforation patency of 8-12 weeks. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ar.24220DOI Listing
March 2020
5 Reads

The association of allergy and chronic suppurative otitis media: A study in a tropical country.

Med J Malaysia 2019 06;74(3):205-208

Universiti Sains Malaysia, School of Dental Sciences, Health Campus, Kota Bharu, Kelantan, Malaysia.

Objective: Chronic suppurative otitis media (CSOM) usually begins as a spontaneous perforation of tympanic membrane due to an acute infection of the middle ear. This study was aimed to evaluate the association between allergy and CSOM.

Methods: A case-control study was carried out among patients with CSOM (cases) and controls were those with no ear pathology. Read More

View Article

Download full-text PDF

Source
June 2019
5 Reads

[Clinical observation of attic retraction pocket by otoendoscopes].

Authors:
J Su P Li X B Ji J H Xie

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2019 Jun;33(6):553-556

Department of Otorhinolaryngology Head and Neck Surgery, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, 510180, China.

To explore the clinical effect, key points and techniques of otoendoscopic surgery in patients with attic retraction pocket. Data of 25 patients (25 ears) of chronic suppurative otitis media who treated with transcanal endoscopic ear surgery for attic retraction pocket were retrospectively analyzed. Patients were examined by otoendoscopes at postoperative 1, 3 and 6 month,respectively. Read More

View Article

Download full-text PDF

Source
http://kns.cnki.net/kcms/detail/detail.aspx?doi=10.13201/j.i
Publisher Site
http://dx.doi.org/10.13201/j.issn.1001-1781.2019.06.019DOI Listing
June 2019
12 Reads

Correlation Between Sensorineural Hearing Loss and Chronic Otorrhea.

Ear Nose Throat J 2019 Sep 29;98(8):482-485. Epub 2019 May 29.

Department of Otorhinolaryngology, Santa Casa de Sao Paulo School of Medical Sciences, São Paulo, Brazil.

Many studies have been trying to correlate chronic otorrhea, both in children and in adults, with the sensorineural hearing loss in the affected ear, but have been obtaining contradictory results. This loss might be due to the likely toxicity of the bacteria involved, effects of inflammatory cytokines, or constant use of ototoxic antibiotics. All the studies evaluated up to the present date compared the affected ear with the normal contralateral ear. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0145561319840573DOI Listing
September 2019
4 Reads

Water protection in patients with tympanostomy tubes in tympanic membrane: a randomized clinical trial.

Einstein (Sao Paulo) 2019 Mar 7;17(2):eAO4423. Epub 2019 Mar 7.

Faculdade de Ciências Médicas, Santa Casa de São Paulo, São Paulo, SP, Brazil.

Objective: To analyze the incidence of otorrhea in the postoperative period of patients submitted to tympanotomy to place ventilation tube, and who did not protect the ear when exposed to water.

Methods: Open, randomized-controlled trial. Eighty patients submitted to unilateral or bilateral ear grommet tympanostomy were included and divided into two groups: Auricular Protection and Non-Protection to water during bathing and activities in water. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.31744/einstein_journal/2019AO4423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394998PMC
March 2019
4 Reads

Endoscopic cartilage tympanoplasty: full thickness and partial thickness tragal graft.

Braz J Otorhinolaryngol 2020 May - Jun;86(3):308-314. Epub 2019 Feb 20.

Rajiv Gandhi Medical College & Chhatrapati Shivaji Maharaj Hospital, Kalwa, Thane, India.

Introduction: Cartilage is the grafting material of choice for certain disorders of the middle ear. The indications for its routine use remain controversial due to the possible detrimental effect on post-operative hearing.

Objective: The present study was carried out to report a personal experience with "tragal cartilage shield" tympanoplasty to compare the results, in terms of graft uptake and hearing improvement, of endoscopic cartilage shield technique using either partial thickness or full thickness tragal cartilage for type 1 tympanoplasty and to highlight the tips for single-handed endoscopic ear surgery. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bjorl.2018.12.006DOI Listing
June 2020
5 Reads

Temporal bone involvement of IgG4-related disease: a rare condition misleading to petrous apicitis causing lateral rectus palsy.

BMJ Case Rep 2019 Feb 26;12(2). Epub 2019 Feb 26.

Department of Otolaryngology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

IgG4-related disease (IgG4-RD) of temporal bone is rare and clinical manifestation mimics infection. A 19-year-old female presented with progressive left earache and intermittent left nasal obstruction. Then, she rapidly developed left lateral rectus palsy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bcr-2018-228550DOI Listing
February 2019
9 Reads

Bacterial causes of otitis media with spontaneous perforation of the tympanic membrane in the era of 13 valent pneumococcal conjugate vaccine.

PLoS One 2019 1;14(2):e0211712. Epub 2019 Feb 1.

ACTIV, Association Clinique et Thérapeutique Infantile du Val-de-Marne, Saint Maur-des-Fossés, France.

After pneumococcal conjugate vaccine (PCV) implementation, the number of acute otitis media (AOM) episodes has decreased, but AOM still remains among the most common diagnoses in childhood. From 2% to 17% of cases of AOM feature spontaneous perforation of the tympanic membrane (SPTM). The aim of this study was to describe the bacteriological causes of SPTM 5 to 8 years years after PCV13 implementation, in 2010. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0211712PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358092PMC
November 2019
16 Reads

Fabrication of levofloxacin polyethylene glycol decorated nanoliposomes for enhanced management of acute otitis media: Statistical optimization, trans-tympanic permeation and in vivo evaluation.

Int J Pharm 2019 Mar 23;559:201-209. Epub 2019 Jan 23.

Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt. Electronic address:

Acute otitis media (AOM), an infection in the middle ear, is usually treated through systemic administration of antibiotics because the stratum corneum of the intact tympanic-membrane (TM) possesses low permeability that holds against the ototopical antibiotics use. Therefore, the objective of this work was to encapsulate levofloxacin (LFX) into polyethylene glycol 400 (PEG 400) decorated nanoliposomes (PNLs) as an approach for drug delivery through the intact tympanic-membrane. LFX loaded-PNLs were primed by ethanol injection technique. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S03785173193007
Publisher Site
http://dx.doi.org/10.1016/j.ijpharm.2019.01.037DOI Listing
March 2019
15 Reads

Canal Wall-Down Mastoidectomy plus Meatoplasty for Extensive Verruca Vulgaris in the Ear Canal and Mastoid Bone.

J Int Adv Otol 2018 Dec;14(3):501-503

Department of Otorhinolaryngology-Head and Neck Surgery, Eulji University, Eulji Medical Center, Seoul, Korea.

Verruca vulgaris is commonly seen on the hands, feet, and face, but rarely in the external auditory canal. We report the case of a 57-year-old woman with a huge papillary mass filling the entire external auditory canal, with destruction of the posterior canal wall and excavation into the mastoid bone. We performed en bloc resection of the whole region affected by verruca vulgaris, including the external auditory canal, mastoid skin, and tympanic membrane using canal wall-down mastoidectomy plus meatoplasty. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5152/iao.2018.4926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354520PMC
December 2018
3 Reads

Studying PCV impact on clinical presentation of otitis media helps to understand its pathogenesis.

Vaccine 2019 01 26;37(1):1-6. Epub 2018 Nov 26.

Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel. Electronic address:

Background: Complex otitis media (OM) may present with intact tympanic membrane or spontaneous otorrhea. We compared dynamics of intact tympanic membrane and spontaneous otorrhea OM following 7- and 13-valent conjugated vaccines (PCV7, PCV13) implementation, since differences in dynamics may imply different underlying mechanisms.

Methods: A prospective, population-based, active surveillance. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S0264410X183157
Publisher Site
http://dx.doi.org/10.1016/j.vaccine.2018.11.054DOI Listing
January 2019
8 Reads

The prevalence of otitis media in 2-3 year old Cameroonian children estimated by tympanometry.

Int J Pediatr Otorhinolaryngol 2018 Dec 6;115:181-187. Epub 2018 Oct 6.

Epidemiology/Health Sciences, Faculty of Social Sciences, University of Tampere, Finland; National Institute for Health and Welfare (THL), Finland.

Background: Acute otitis media is a common illness in children under-five years of age and associated with major health care resources in high-income countries. However, there is paucity of data on its epidemiology and clinical presentation in low-income countries. We estimated the prevalence of otitis media and assessed risk factors among children in Cameroon. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijporl.2018.10.007DOI Listing
December 2018
43 Reads

Anatomical and functional results of ossiculoplasty using titanium prosthesis.

Acta Otorhinolaryngol Ital 2018 Aug;38(4):377-383

AP-HP, Pitié-Salpêtrière Hospital, Otology, Auditory Implants and Skull Base Surgery Department, Paris, France.

Titanium ossicular chain replacement prosthesis is often used for rehabilitation of the columellar effect in otologic surgeries. This retrospective study aims to analyse the anatomical and functional results of surgeries in which a titanium prosthesis was used. Two hundred and eighty procedures in 256 patients operated on in a tertiary referral center were analysed. Read More

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146578PMC
http://dx.doi.org/10.14639/0392-100X-1700DOI Listing
August 2018
7 Reads

Effect of combination therapy with ceftizoxime and clotrimazole in the treatment of otomycosis.

Curr Med Mycol 2018 Mar;4(1):18-23

Department of Ear, Nose, and Throat, Faculty of Medicine, Roohani Hospital, Babol University of Medical Sciences, Babol, Iran.

Background And Purpose: There are controversial findings regarding the efficacy of antifungal drugs in the treatment of a ruptured eardrum following fungal infections. Regarding this, the aim of the present study was to evaluate the therapeutic effect of the co-administration of antifungal and antibacterial agents in the treatment of otomycosis with tympanic membrane perforation.

Materials And Methods: This analytical, clinical trial was conducted on 87 patients with otomycosis showing no bacterial elements in the direct observation and culture. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18502/cmm.4.1.30DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101155PMC
March 2018
45 Reads

Microbial otitis media: recent advancements in treatment, current challenges and opportunities.

J Med Microbiol 2018 Oct 7;67(10):1417-1425. Epub 2018 Aug 7.

2​Department of Human and Molecular Genetics, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, USA.

Otitis media (OM) is a common disease affecting humans, especially paediatric populations. OM refers to inflammation of the middle ear and can be broadly classified into two types, acute and chronic. Bacterial infection is one of the most common causes of OM. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1099/jmm.0.000810DOI Listing
October 2018
5 Reads

Pattern of tympanic membrane perforation in a tertiary hospital in Nigeria.

Niger J Clin Pract 2018 Aug;21(8):1044-1049

Department of ENT, Lagos University Teaching Hospital, Lagos, Nigeria.

Background/objectives: Tympanic membrane perforation is a common otological disorder with associated hearing impairment. This study aimed at determining the clinicoepidemiological pattern, etiological factors, clinical presentation, and management of tympanic membrane perforation in a tertiary hospital in Nigeria.

Materials And Methods: This was a prospective, hospital-based study of patients with the clinical finding of perforated tympanic membrane. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/njcp.njcp_380_17DOI Listing
August 2018
3 Reads

Preliminary outcomes of endoscopic middle-ear surgery in 103 cases: a UK experience.

J Laryngol Otol 2018 Jun;132(6):493-496

Department of Otolaryngology,University Hospital Monklands, NHS Lanarkshire,Airdrie,Scotland,UK.

Background: Totally endoscopic ear surgery and endoscope-assisted microsurgery are still new concepts, with relatively few centres in the UK performing them. Advantages include better visualisation of difficult to reach areas, such as the sinus tympani, and limited external incisions. This paper reports our short-term outcomes for endoscopic middle-ear surgery. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S0022215118000695DOI Listing
June 2018
10 Reads

Immediate effects of a rhino-pharyngeal clearance protocol in nasal obstruction and middle ear condition of children under 3 years of age with upper respiratory infections: A randomized controlled trial.

Acta Otorrinolaringol Esp 2019 Jul - Aug;70(4):192-199. Epub 2018 Jun 8.

Department of Intensive Care and Pediatric Service, Grand Hôpital de Charleroi - GHDC, Charleroi, Belgium.

Introduction And Objectives: Children up to 2 years old are at high risk of respiratory infections and nasal irrigation is often prescribed. Yet, to date there is no sufficient knowledge about its immediate effects on the nasopharynx and middle ear. Therefore, this study aimed to analyze the effect of a rhino-pharyngeal clearance intervention protocol on nasal obstruction and middle ear condition in children under 3 years of age with URTI. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.otorri.2018.03.004DOI Listing
January 2020
13 Reads

Isolation and antimicrobial drug susceptibility pattern of bacterial pathogens from pediatric patients with otitis media in selected health institutions, Addis Ababa, Ethiopia: a prospective cross-sectional study.

BMC Ear Nose Throat Disord 2018 24;18. Epub 2018 May 24.

3School of Nursing and Midwifery, Department of Pediatric Nursing, College of Health and Medical Sciences, Haramaya University, P.O.BOX, 235 Harar, Ethiopia.

Background: Otitis media is inflammation of the middle ear and tympanic membrane, which often occurs after an acute upper respiratory tract infection. It is the most common episode of infection in children and the second most important cause of hearing loss affecting 1.23 billion people, thus ranked fifth global burden of disease with a higher incidence in sub-Saharan Africa. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12901-018-0056-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968499PMC
May 2018
26 Reads

[Different states of otitis media were retrospectively analyzed of myringoplasty].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2017 Oct;31(19):1473-1477

Department of Otolaryngology Head and Neck Surgery,EENT Hospital of Fudan University.

Through analysis of the tympanic membrane perforation rate and hearing improvement rate with chronic suppurative otitis media (CSOM) by myringoplasty,to observe the effect of different preoperative conditions such as middle ear lesion,eustachian tube (ET) function and infection status on the postoperative curative effect.Retrospective analysis of EENT Hospital of Fudan University from January 2012 to November 2016 during the 203 cases (203 ears) with clinical data of myringoplasty: according to intraoperative exploration of the presence of purulent secretions in the tympanic cavity,divided into infection active group and infection quiescence group; according to the preoperative results of the function of ET with acoustic impedance test divided into dysfunction or good group; according to the preoperative temporal bone HRCT suggested that the middle ear (mastoid cells,tympanic antrum and tympanic cavity) with or without soft tissue density,divided into the group with no focal lesion and the group with focal lesion. Review endoscopy and pure tone audiometry after 3 to 6 months. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.13201/j.issn.1001-1781.2017.19.003DOI Listing
October 2017
8 Reads

Aerobic bacteria associated with chronic suppurative otitis media in Angola.

Infect Dis Poverty 2018 May 3;7(1):42. Epub 2018 May 3.

Clinical Microbiology, Department of Translational Medicine, Faculty of Medicine, Lund University, Malmö, Sweden.

Background: Chronic suppurative otitis media (CSOM) is an important cause of hearing loss in children and constitutes a serious health problem globally with a strong association to resource-limited living conditions. Topical antibiotics combined with aural toilet is the first-hand treatment for CSOM but antimicrobial resistance and limited availability to antibiotics are obstacles in some areas. The goal of this study was to define aerobic pathogens associated with CSOM in Angola with the overall aim to provide a background for local treatment recommendations. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40249-018-0422-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932871PMC
May 2018
25 Reads

Atypical presentation of aural tuberculosis with complication.

BMJ Case Rep 2018 Mar 9;2018. Epub 2018 Mar 9.

Department of ENT and Head and Neck Surgery, All India Institute of Medical Sciences, New Delhi, India.

Tuberculosis involving mastoid and ear is an uncommon entity presenting with myriads of non-specific features and difficult to diagnose, being a paucibacillary condition. The involvement of otomastoid compartment is hypothesised to be of haematogenous origin. Rarely it can spread directly via tympanic membrane perforation or via reflux through eustachian tube. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bcr-2017-222482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847930PMC
March 2018
29 Reads

A randomized study of four different types of tympanostomy ventilation tubes - Full-term follow-up.

Int J Pediatr Otorhinolaryngol 2018 Apr 7;107:140-144. Epub 2018 Feb 7.

Dept of Otorhinolaryngology, Västmanland County Hospital, Sweden; Centre for Clinical Research, Uppsala University, Västmanland County Hospital, Västerås, Sweden; Dept of Otorhinolaryngology, Akershus University Hospital and University of Oslo, Campus Ahus, Oslo, Norway.

Objective: To evaluate the impact of tympanostomy ventilation tube material (silicone vs fluoroplastic) and shape (short vs long) regarding time to extrusion, occurrence of otorrhea, occlusion, tube removal and occurrence of persistent perforation.

Methods And Material: Four different types of ventilation tubes were used; Long Armstrong tubes, Donaldson tubes, Shepard tubes and straight tubes, representing four specific combinations of VT material (silicone or fluoroplastic) and shape (short, double flanged or long, single flanged). Four hundred children scheduled for bilateral tube insertion were included in a randomized trial. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijporl.2018.02.012DOI Listing
April 2018
21 Reads

Etiology of Acute Otitis Media and Characterization of Pneumococcal Isolates After Introduction of 13-Valent Pneumococcal Conjugate Vaccine in Japanese Children.

Pediatr Infect Dis J 2018 06;37(6):598-604

From the Department of Infectious Diseases, Keio University, School of Medicine.

Background: Acute otitis media is a leading cause of childhood morbidity and antibiotic prescriptions. We examined etiologic changes in acute otitis media after introduction of 13-valent pneumococcal conjugate vaccine as routine immunization for Japanese children in 2014. Serotypes, resistance genotypes, antibiotic susceptibilities and multilocus sequence typing of pneumococcal isolates were also characterized. Read More

View Article

Download full-text PDF

Source
http://Insights.ovid.com/crossref?an=00006454-201806000-0002
Publisher Site
http://dx.doi.org/10.1097/INF.0000000000001956DOI Listing
June 2018
14 Reads

Prevalence of chronic ear disease among HIV+ children in Sub-Saharan Africa.

Int J Pediatr Otorhinolaryngol 2017 Dec 19;103:133-136. Epub 2017 Oct 19.

Department of Otolaryngology-Head & Neck Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA; Department of Pediatrics, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA. Electronic address:

Objectives: To determine the prevalence of chronic ear disease in HIV+, highly active anti-retroviral therapy (HAART)-treated children and compare this to the prevalence in healthy children of similar age living in a similar setting.

Introduction: From previous clinical work in Ethiopia, we suspected that chronic middle ear disease was common both in the general pediatric population and especially among children with HIV/AIDS. Few studies have examined the prevalence of chronic ear disease in HIV + children, particularly in those treated with HAART. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijporl.2017.10.024DOI Listing
December 2017
39 Reads

Should Nasal Function be Considered Prior to Tympanoplasty?

J Int Adv Otol 2018 Apr 21;14(1):53-57. Epub 2017 Nov 21.

Department of Biostatistics, Uludağ University School of Medicine, Bursa, Turkey.

Objective: To evaluate the association between nasal airway function and Eustachian tube (ET) functions and their impact on tympanoplasty in patients with chronic suppurative otitis media (CSOM).

Materials And Methods: The study group (CSOM group) consisted of 33 patients scheduled to undergo tympanoplasty for CSOM. Two control groups were formed: a nasal septal deviation (NSD) group of 25 patients scheduled to undergo nasal surgery for NSD, and a control group of 25 healthy individuals with no otologic or rhinologic symptoms. Read More

View Article

Download full-text PDF

Source
http://www.advancedotology.org/eng/makale/1178/97/Full-Text
Publisher Site
http://dx.doi.org/10.5152/iao.2017.3624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354491PMC
April 2018
8 Reads

Correlation between sensorineural hearing loss and chronic otorrhea.

Ear Nose Throat J 2017 Oct-Nov;96(10-11):E43-E46

Santa Casa de Sao Paulo School of Medical Sciences, Rua Itapeva 366 cj 74, CEP 01332-000 - São Paulo, Brazil.

Many studies have attempted to correlate chronic otorrhea in children and in adults with the sensorineural hearing loss in the affected ear, with contradictory results. This loss might be the result of the likely toxicity of the bacteria involved, effects of inflammatory cytokines, or constant use of ototoxic antibiotics. All studies evaluated to date compared the affected ear with the normal contralateral ear. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0145561317096010-1108DOI Listing
July 2018
14 Reads

The role of the nasal and paranasal sinus pathologies on the development of chronic otitis media and its subtypes: A computed tomography study.

Niger J Clin Pract 2017 Sep;20(9):1156-1160

Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine, Bülent Ecevit University, Zonguldak, Turkey.

Objective: This objective of this study is to evaluate the presence and the coincidence of common nasal and paranasal sinus pathologies in adults suffering from chronic otitis media (COM) and its subtypes.

Materials And Methods: The study group comprised 354 ears of 177 patients who underwent tympanoplasty with or without mastoidectomy from January 2013 to February 2015 due to uni/bilateral COM. Chronic suppurative otitis media, intratympanic tympanosclerosis (ITTS), cholesteatoma, and tympanic membrane with retraction pockets constituted subtypes of COM. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/njcp.njcp_124_16DOI Listing
September 2017
1 Read

Knowledge and care seeking practices for ear infections among parents of under five children in Kigali, Rwanda: a cross-sectional study.

BMC Ear Nose Throat Disord 2017 10;17. Epub 2017 Oct 10.

Head and Neck Surgery & Communication Sciences, Duke University, Durham, USA.

Background: Infections affecting the middle ear are a common childhood occurrence. Some cases may present with ear discharge through a tympanic membrane perforation which may heal spontaneously. However, up to 5% or more cases of those affected have persistent ear discharge. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12901-017-0040-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5633896PMC
October 2017
18 Reads

Cochlear implant electrode array exposure: A delayed complication.

Ear Nose Throat J 2017 Jul;96(7):E40-E43

Department of Communication Disorders and Sciences, Rush University Medical Center, Chicago, IL, USA.

Exposure of the cochlear implant electrode array as a late complication has been reported rarely in the literature. A retrospective analysis revealed 4 patients presenting with exposure of their cochlear implant electrode arrays from 2 to 17 years after implantation. Data collected from these 4 patients were surgical implantation approach, type of implant, age at implant, interval between implant and complication, surgical correction of the problem, pathology at the time of correction, and length of follow-up after intervention. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/014556131709600708DOI Listing
July 2017
15 Reads

Optimisation of peptides that actively cross the tympanic membrane by random amino acid extension: a phage display study.

J Drug Target 2018 02 16;26(2):127-134. Epub 2017 Aug 16.

a Department of Surgery, Division of Otolaryngology , School of Medicine, University of California , La Jolla , CA , USA.

Local treatment of middle ear (ME) disease currently requires surgical penetration of the tympanic membrane (TM). We previously discovered 12-mer peptides that are actively transported across the intact TM, a process that could be used for non-invasive drug delivery into the ME. To optimise transport and provide further understanding of the peptides transport mechanism, we extended two of the candidate peptides by six additional amino acids at random, and screened the resulting 18-mers libraries on TMs of rats with active bacterial otitis media (OM) for transport efficiency using phage display. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/1061186X.2017.1347791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223256PMC
February 2018
3 Reads

Ototoxicity of boric acid powder in a rat animal model.

Braz J Otorhinolaryngol 2018 May - Jun;84(3):332-337. Epub 2017 Apr 22.

GATA Haydarpasa Training Hospital, Department of Otorhinolaryngology, Istanbul, Turkey.

Introduction: Boric acid, which has antiseptic and acidic properties, is used to treat external and middle ear infections. However, we have not found any literature about the effect of boric acid powder on middle ear mucosa and inner ear.

Objective: The purpose of this study is to investigate possible ototoxic effects of boric acid powder on cochlear outer hair cell function and histological changes in middle ear mucosa in a rat animal model. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bjorl.2017.03.010DOI Listing
June 2018
22 Reads

Tubotympanic system functioning.

Eur Ann Otorhinolaryngol Head Neck Dis 2017 May 29;134(3):177-184. Epub 2017 Apr 29.

Service ORL et de Chirurgie Cervico-Faciale, Hôpital Nord, CHU de Saint-Étienne, 42055 Saint-Étienne Cedex 2, France.

The Eustachian (auditory) tube and tympanomastoid cavities form an anatomic and functional whole that cannot easily be divided, and is therefore known as the "tubotympanic system". The system has been the focus of several studies, with complex and sometimes contradictory results, making an overview of its functioning difficult to obtain. The objective of the present article is to review the current state of knowledge, as an indispensable preliminary to understanding tubotympanic system dysfunction, and notably the development of chronic otitis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.anorl.2017.03.010DOI Listing
May 2017
14 Reads

Factors affecting sound energy absorbance in acute otitis media model of chinchilla.

Hear Res 2017 07 10;350:22-31. Epub 2017 Apr 10.

School of Aerospace and Mechanical Engineering and Biomedical Engineering Center, University of Oklahoma, Norman, OK, USA. Electronic address:

Acute otitis media (AOM) is a rapid-onset infection of the middle ear which results in middle ear pressure (MEP), middle ear effusion (MEE), and structural changes in middle ear tissues. Previous studies from our laboratory have identified that MEP, MEE, and middle ear structural changes are three factors affecting tympanic membrane (TM) mobility and hearing levels (Guan et al., 2014, 2013). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.heares.2017.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504283PMC
July 2017
3 Reads

[The application of the method of radiofrequency myringotomy under the experimental conditions and in the clinical practice].

Vestn Otorinolaringol 2017;82(1):52-55

I.M. Sechenov First Moscow State Medical University, Moscow, Russia, 119991.

Exudative otitis media is a widespread pathological condition in the human population. In the recent years, the treatment with the electric current having the frequency up to 3.8 MHz has found the increasingly frequent application, in addition to shunting and laser myringotomy, for the perforation of the tympanic membrane to facilitate removal of exudate. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17116/otorino201782152-55DOI Listing
June 2017
7 Reads

Epidemiology of Otitis Media with Spontaneous Perforation of the Tympanic Membrane in Young Children and Association with Bacterial Nasopharyngeal Carriage, Recurrences and Pneumococcal Vaccination in Catalonia, Spain - The Prospective HERMES Study.

PLoS One 2017 1;12(2):e0170316. Epub 2017 Feb 1.

Medical Department, Pfizer, Madrid, Spain.

The Epidemiology of otitis media with spontaneous perforation of the tympanic membrane and associated nasopharyngeal carriage of bacterial otopathogens was analysed in a county in Catalonia (Spain) with pneumococcal conjugate vaccines (PCVs) not included in the immunization programme at study time. A prospective, multicentre study was performed in 10 primary care centres and 2 hospitals (June 2011-June 2014), including all otherwise healthy children ≥2 months ≤8 years with otitis media presenting spontaneous tympanic perforation within 48h. Up to 521 otitis episodes in 487 children were included, showing by culture/PCR in middle ear fluid (MEF): Haemophilus influenzae [24. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0170316PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287464PMC
August 2017
34 Reads

Acute bacterial meningitis caused by acute otitis media in adults: A series of 12 patients.

Ear Nose Throat J 2017 Jan;96(1):20-28

Department of Otorhinolaryngology-Head and Neck Surgery, Soroka University Medical Center and Faculty of Health Sciences, Beer Sheva, Israel.

We conducted a retrospective chart review to characterize the outcomes of 12 patients-9 men and 3 women, aged 21 to 79 years (mean: 49)-who had been treated at our tertiary care center for acute bacterial meningitis caused by acute otitis media (ABMAO). Fever was the most common presenting sign/symptom, observed in 8 patients, followed by otalgia, neck stiffness, headache, and confusion. An opaque and bulging tympanic membrane was observed in 8 patients. Read More

View Article

Download full-text PDF

Source
January 2017
82 Reads

Prospective evaluation of the aetiology of acute otitis media with spontaneous tympanic membrane perforation.

Clin Microbiol Infect 2017 Jul 19;23(7):486.e1-486.e6. Epub 2017 Jan 19.

Paediatric Highly Intensive Care Unit, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Objectives: To evaluate the aetiological role of the main bacterial pathogens associated with acute otitis media (AOM) in children with AOM and spontaneous tympanic membrane perforation (STMP).

Methods: Between 1 May 2015 and 30 April 2016, 177 children, aged 6 months to 7 years, with AOM complicated by STMP within 12 h were prospectively enrolled. Middle ear fluid (MEF) was tested by real-time PCR for Streptococcus pneumoniae, non-typeable Haemophilus influenzae, Streptococcus pyogenes, Moraxella catarrhalis and Staphylococcus aureus. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cmi.2017.01.010DOI Listing
July 2017
15 Reads

The effects of ventilation tubes versus no ventilation tubes for recurrent acute otitis media or chronic otitis media with effusion in 9 to 36 month old Greenlandic children, the SIUTIT trial: study protocol for a randomized controlled trial.

Trials 2017 01 19;18(1):30. Epub 2017 Jan 19.

Department of Otorhinolaryngology and Maxillofacial Surgery, Zealand University Hospital, Køge, Denmark.

Background: The prevalence of otitis media in Greenlandic children is one of the highest in the world. International studies have shown that otitis-prone children may benefit from tubulation of the tympanic membrane. However, it is unknown whether these results can be applied to Greenlandic children and trials on the effects of ventilation tubes in high-risk populations have, to our knowledge, never been conducted. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13063-016-1770-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5248475PMC
January 2017
20 Reads