97 results match your criteria Middle Ear Eustachian Tube Inflammation Infection


A model of chronic, transmissible Otitis Media in mice.

PLoS Pathog 2019 04 10;15(4):e1007696. Epub 2019 Apr 10.

Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, Georgia, United States of America.

Infection and inflammation of the middle ears that characterizes acute and chronic otitis media (OM), is a major reason for doctor visits and antibiotic prescription, particularly among children. Nasopharyngeal pathogens that are commonly associated with OM in humans do not naturally colonize the middle ears of rodents, and experimental models in most cases involve directly injecting large numbers of human pathogens into the middle ear bullae of rodents, where they induce a short-lived acute inflammation but fail to persist. Here we report that Bordetella pseudohinzii, a respiratory pathogen of mice, naturally, efficiently and rapidly ascends the eustachian tubes to colonize the middle ears, causing acute and chronic histopathological changes with progressive decrease in hearing acuity that closely mimics otitis media in humans. Read More

View Article

Download full-text PDF

Source
http://dx.plos.org/10.1371/journal.ppat.1007696
Publisher Site
http://dx.doi.org/10.1371/journal.ppat.1007696DOI Listing
April 2019
3 Reads

Towards an optical diagnostic system for otitis media using a combination of otoscopy and spectroscopy.

J Biophotonics 2019 Feb 5:e201800305. Epub 2019 Feb 5.

Center of Optical and Electromagnetic Research, South China Academy of Advanced Optoelectronics, South China Normal University, Guangzhou, China.

An improved method, where conventional otoscope investigation of human suspicious otitis media is combined with diffuse reflectance spectroscopy and gas in scattering media absorption spectroscopy (GASMAS) is being developed. Otitis media is one of the most common infectious diseases in children, whose Eustachian tube connecting the middle ear with the nasal cavity is more horizontal than for adults, which leads to impaired fluid drainage. At present, the use of an otoscope to visually observe possible changes in the tympanic membrane appearance is the main diagnostics method for otitis media. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jbio.201800305DOI Listing
February 2019
1 Read

Comparison of two techniques for transpharyngeal endoscopic auditory tube diverticulotomy in the horse.

J Vet Sci 2018 Nov;19(6):835-839

Department of Clinical Sciences, Colorado State University, Fort Collins, CO 80523, USA.

Auditory tube diverticula, also known as guttural pouches, are naturally occurring dilations of the auditory tube in horses that communicate with the nasopharynx through a small ostium. Infection and select other conditions can result in inflammation and narrowing of the nasopharyngeal ostium, which prevents drainage of fluid or egress of air and can lead to persistent infection or guttural pouch tympany. Auditory tube diverticulotomy allows continuous egress from the auditory tube diverticula and is a feature of disease treatment in horses, in which medical treatment alone is not successful. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4142/jvs.2018.19.6.835DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265580PMC
November 2018
2 Reads

Radiological differences between HIV-positive and HIV-negative children with cholesteatoma.

Int J Pediatr Otorhinolaryngol 2018 Jul 14;110:6-11. Epub 2018 Apr 14.

Division of Otorhinolaryngology, Faculty of Health Sciences, University of Cape Town, South Africa.

Introduction: HIV-positive children are possibly more prone to developing cholesteatoma. Chronic inflammation of the middle ear cleft may be more common in patients with HIV and this may predispose HIV-positive children to developing cholesteatoma. There are no studies that describe the radiological morphology of the middle ear cleft in HIV-positive compared to HIV-negative children with cholesteatoma. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijporl.2018.04.011DOI Listing
July 2018
1 Read

Expression, Distribution, and Role of C-Type Lectin Receptors in the Human and Animal Middle Ear and Eustachian Tube: A Review.

Molecules 2018 Mar 22;23(4). Epub 2018 Mar 22.

Department of Otorhinolaryngology-Head and Neck Surgery, Graduate School, Kyung Hee University, Seoul 02447, Korea.

Otitis media (OM) is a group of inflammatory diseases of the middle ear (ME), regardless of cause or pathological mechanism. Among the molecular biological studies assessing the pathology of OM are investigations into the expression of C-type lectin receptors (CLR) in the ME and Eustachian tube (ET). To date, nine studies have evaluated CLR expression in the ME and ET. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/molecules23040734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017961PMC
March 2018
12 Reads

Atypical presentation of aural tuberculosis with complication.

BMJ Case Rep 2018 Mar 9;2018. Epub 2018 Mar 9.

Department of ENT and Head and Neck Surgery, All India Institute of Medical Sciences, New Delhi, India.

Tuberculosis involving mastoid and ear is an uncommon entity presenting with myriads of non-specific features and difficult to diagnose, being a paucibacillary condition. The involvement of otomastoid compartment is hypothesised to be of haematogenous origin. Rarely it can spread directly via tympanic membrane perforation or via reflux through eustachian tube. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bcr-2017-222482DOI Listing
March 2018
12 Reads

Cilia distribution and polarity in the epithelial lining of the mouse middle ear cavity.

Sci Rep 2017 03 30;7:45870. Epub 2017 Mar 30.

Department of Cell Biology Emory University, Atlanta, USA.

The middle ear conducts sound to the cochlea for hearing. Otitis media (OM) is the most common illness in childhood. Moreover, chronic OM with effusion (COME) is the leading cause of conductive hearing loss. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep45870DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372464PMC
March 2017
1 Read

Accumulation of Regulatory T Cells and Chronic Inflammation in the Middle Ear in a Mouse Model of Chronic Otitis Media with Effusion Induced by Combined Eustachian Tube Blockage and Nontypeable Haemophilus influenzae Infection.

Infect Immun 2016 01 9;84(1):356-64. Epub 2015 Nov 9.

Department of Otolaryngology, Faculty of Medicine, Oita University, Oita, Japan

Nontypeable Haemophilus influenzae (NTHi) is associated with chronic otitis media (COM). In this study, we generated a murine model of COM by using eustachian tube (ET) obstruction and NTHi (10(7) CFU) inoculation into the tympanic bulla, and we investigated the relationship between regulatory T cells (Treg) and chronic inflammation in the middle ear. Middle ear effusions (MEEs) and middle ear mucosae (MEM) were collected at days 3 and 14 and at 1 and 2 months after inoculation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/IAI.01128-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694021PMC
January 2016
17 Reads

Middle ear function in sinonasal polyposis.

Eur Arch Otorhinolaryngol 2016 Oct 31;273(10):2911-6. Epub 2015 Oct 31.

Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Ghaem Educational Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.

Nasal airway patency has long been considered a major factor in ear health. The aim of this study was to determine the effect of sinonasal polyposis on middle ear and eustachian tube (ET) functionality. Forty-four individuals with polyposis, 23 with non-polyposis nasal obstruction, and 23 healthy controls were enrolled. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00405-015-3812-5DOI Listing
October 2016
5 Reads
1.610 Impact Factor

Associations between peripheral vertigo and gastroesophageal reflux disease.

Med Hypotheses 2015 Sep 20;85(3):333-5. Epub 2015 Jun 20.

Lithuanian University of Health Sciences, Academy of Medicine, Department of Neurology, Lithuania.

We hypothesize that peripheral vertigo is associated with gastroesophageal reflux disease (GERD). Two mechanisms could be considered – gastric acids may directly irritate the respiratory mucosa and cause inflammation, or Helicobacter pylori (H. pylori) could be present and cause local infection. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.mehy.2015.06.007DOI Listing
September 2015
2 Reads

Molecular biology of cholesteatoma.

Rom J Morphol Embryol 2014 ;55(1):7-13

Department of Otolaryngology, Head and Neck Surgery, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania;

Cholesteatoma is a non-neoplastic, keratinizing lesion, characterized by the proliferation of epithelium with aberrant micro-architecture into the middle ear and mastoid cavity. The exact pathogenic molecular mechanisms behind the formation and propagation of cholesteatoma remain unclear. Immunohistochemical examinations of the matrix and perimatrix have considerably improved the knowledge of cholesteatoma pathogenesis. Read More

View Article

Download full-text PDF

Source
April 2015
6 Reads
9 Citations
0.660 Impact Factor

Development of animal models of otitis media.

Korean J Audiol 2013 Apr 16;17(1):9-12. Epub 2013 Apr 16.

Department of Otolaryngology-Head and Neck Surgery, Soonchunhyang University College of Medicine, Seoul, Korea.

Otitis media is defined as inflammation of the middle ear, including the auditory ossicles and the Eustachian tube. Otitis media is a major health problem in many societies. The causes of otitis media includes infection and anatomic/physiologic, host, and environmental factors. Read More

View Article

Download full-text PDF

Source
http://ejao.org/journal/view.php?doi=10.7874/kja.2013.17.1.9
Publisher Site
http://dx.doi.org/10.7874/kja.2013.17.1.9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936519PMC
April 2013
5 Reads

Otitis media: diagnosis and treatment.

Am Fam Physician 2013 Oct;88(7):435-40

University of Michigan, Ann Arbor, MI, USA.

Acute otitis media is diagnosed in patients with acute onset, presence of middle ear effusion, physical evidence of middle ear inflammation, and symptoms such as pain, irritability, or fever. Acute otitis media is usually a complication of eustachian tube dysfunction that occurs during a viral upper respiratory tract infection. Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis are the most common organisms isolated from middle ear fluid. Read More

View Article

Download full-text PDF

Source
October 2013
3 Reads

Autoinflation for hearing loss associated with otitis media with effusion.

Cochrane Database Syst Rev 2013 May 31(5):CD006285. Epub 2013 May 31.

Department of Primary Care Health Sciences, University of Oxford, Radcliffe Observatory Quarter, Woodstock Road, Oxford, UK, OX2 6GG.

Background: This is an update of a Cochrane review first published in The Cochrane Library in Issue 4, 2006.Otitis media with effusion (OME) or 'glue ear' is an accumulation of fluid in the middle ear, in the absence of acute inflammation or infection. It is the commonest cause of acquired hearing loss in childhood and the usual reason for insertion of 'grommets'. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/14651858.CD006285.pub2
Publisher Site
http://dx.doi.org/10.1002/14651858.CD006285.pub2DOI Listing
May 2013
17 Reads

Lower nasopharyngeal epithelial cell repair and diminished innate inflammation responses contribute to the onset of acute otitis media in otitis-prone children.

Med Microbiol Immunol 2013 Aug 11;202(4):295-302. Epub 2013 Apr 11.

Rochester General Hospital Research Institute, Rochester General Hospital, 1425 Portland Ave., Rochester, NY 14621, USA.

About 30 % of young children experience excessive, frequent episodes of middle ear infection and are classified as acute otitis media prone (OP). Streptococcus pneumoniae (Spn) is a predominant otopathogen in OP and non-OP (NOP) children. The pathogenesis of middle ear infection involves otopathogen nasopharyngeal (NP) colonization followed by an upper respiratory viral infection that modifies the NP environment to allow a sufficient inoculum of bacteria to reflux via the Eustachian tube into the middle ear space. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00430-013-0293-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943207PMC
August 2013
13 Reads

Novel rat model of tympanostomy tube otorrhea.

Int J Pediatr Otorhinolaryngol 2012 Feb 22;76(2):179-82. Epub 2011 Dec 22.

Department of Otolaryngology, University of Florida, Gainesville, FL 32610, USA.

Objective: Tympanostomy tube otorrhea (TTO), caused by the presence of pathogenic bacteria in the middle ear, is the most common complication of TT insertion. No studies have described a reproducible animal model of TTO. We aimed to develop a rat model of TTO which, in turn, could be used to assay the levels of TNF-α and IL-1β through the course of the infection. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijporl.2011.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260415PMC
February 2012
3 Reads

Recent advances in otitis media.

Pediatr Infect Dis J 2009 Oct;28(10 Suppl):S133-7

Department of Pediatrics, Boston University School of Medicine, Boston, MA, USA.

Otitis media (OM) is a pervasive illness in infants and children, and many children suffer multiple episodes during the first years of life. High rates of acute otitis media (AOM) are reported in developed and emerging countries. Early onset is common in both settings. Read More

View Article

Download full-text PDF

Source
https://insights.ovid.com/crossref?an=00006454-200910001-000
Publisher Site
http://dx.doi.org/10.1097/INF.0b013e3181b6d81aDOI Listing
October 2009
1 Read

Theories of otitis media pathogenesis, with a focus on Indigenous children.

Med J Aust 2009 Nov;191(9 Suppl):S50-4

School of Paediatrics and Child Health, University of Western Australia, Perth, WA, Australia.

Otitis media is a common childhood illness associated with hearing loss, social disadvantage and medical costs. Prevalence and severity are high among Indigenous children. Respiratory bacterial and viral pathogens ascend the eustachian tube from the nasopharynx to the middle ear, causing inflammation, fluid accumulation, and bulging of the tympanic membrane, with or without pain. Read More

View Article

Download full-text PDF

Source
November 2009
2 Reads

Allergic rhinitis, histamine, and otitis media.

Allergy Asthma Proc 2009 Sep-Oct;30(5):470-81

Juniata College, Huntington, Pennsylvania, USA.

Otitis media (OM) is a common and costly medical condition, especially in children. Most episodes of OM are associated with an upper respiratory viral infection and are short-lived and self-limiting with or without medical treatment. However, chronic OM with effusion (OME) has significant sequelae, is refractory to most medical treatments, and frequently requires surgical intervention. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2500/aap.2009.30.3272DOI Listing
December 2009
3 Reads

Relationship between pediatric obesity and otitis media with effusion.

Curr Allergy Asthma Rep 2009 Nov;9(6):465-72

Although eustachian tube dysfunction and bacterial infection have been shown to cause otitis media with effusion (OME), other etiologies are possible. One of the most common medical conditions in children is obesity, which can have effects throughout the body. Little is known, however, about the relationship between obesity and OME. Read More

View Article

Download full-text PDF

Source
November 2009

Role of adenoids and adenoiditis in children with allergy and otitis media.

Curr Allergy Asthma Rep 2009 Nov;9(6):460-4

Department of Pediatric Sciences, Foundation IRCCS Policlinico San Matteo-University of Pavia, P.le Golgi, 2-27100, Pavia, Italy.

Adenoids and/or tonsil inflammation with concomitant obstructive hypertrophy is one of the oldest and most common pediatric problems. Adenoids are a component of Waldeyer's ring and because of their anatomic position can be relevant in the pathogenesis of otitis media when they are inflamed and/or enlarged. Adenoid pads can create mechanical eustachian tube obstruction. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/content/pdf/10.1007/s11882-009-0068
Web Search
November 2009
6 Reads

Otitis Media: A Review, with a Focus on Alternative Treatments.

Probiotics Antimicrob Proteins 2009 Jun 4;1(1):45-59. Epub 2009 Mar 4.

Department of Microbiology, University of Stellenbosch, Private Bag X1, 7602, Matieland (Stellenbosch), South Africa.

Otitis media (OM) is the accumulation of fluids in the middle ear, with or without symptoms of inflammation. The infection is caused by dysfunction or obstruction of the eustachian tube and is most commonly diagnosed in children under the age of two. The microbiology of OM differs, with Streptococcus pneumoniae, non-typeable Haemophilus influenzae and Moraxella catarrhalis the most commonly isolated pathogens. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s12602-009-9008-9
Publisher Site
http://dx.doi.org/10.1007/s12602-009-9008-9DOI Listing
June 2009
1 Read

Complications of surgery for diseases of the guttural pouch.

Authors:
David E Freeman

Vet Clin North Am Equine Pract 2008 Dec;24(3):485-97, vii

Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Box 100136, Gainesville, FL 32610-0136, USA.

Guttural pouch diseases pose serious challenges in diagnosis and treatment. Complications from treatment are common and often life-threatening, largely because the unique anatomy of the guttural pouches brings them into intimate contact with the nervous, respiratory, and cardiovascular systems. There is little forgiveness for surgical errors, and so the surgeon should focus on ways to anticipate and prevent them. Read More

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S074907390800058
Publisher Site
http://dx.doi.org/10.1016/j.cveq.2008.10.003DOI Listing
December 2008
3 Reads

[Recurrent respiratory infections with severely damaged lung functions--Kartagener's syndrome--case report].

Med Pregl 2008 May-Jun;61(5-6):295-8

Klincki centar "Kragujevac", Interna klinika, Medicinski fakultet, Kragujevac.

Introduction: Kartagener's (or Siewert) syndrome represents a clinical presentation of primary ciliary diskinesia (PCD) with 3 dominant symptoms: bronchiectasiae, chronic sinusitis and situs viscerum inversus totalis or dextrocardia, only. Siewet demonstrated the first case of this clinical phenomenon in 1904, which was recognized by Kartagener in 1933, as a congenital disorder. PCD is an autosomal recessive disease with extensive genetic heterogenity. Read More

View Article

Download full-text PDF

Source
January 2009
2 Reads

Lysozyme M deficiency leads to an increased susceptibility to Streptococcus pneumoniae-induced otitis media.

BMC Infect Dis 2008 Oct 8;8:134. Epub 2008 Oct 8.

Gonda Department of Cell and Molecular Biology, House Ear Institute, Los Angeles, CA, USA.

Background: Lysozyme is an antimicrobial innate immune molecule degrading peptidoglycan of the bacterial cell wall. Lysozyme shows the ubiquitous expression in wide varieties of species and tissues including the tubotympanum of mammals. We aim to investigate the effects of lysozyme depletion on pneumococcal clearance from the middle ear cavity. Read More

View Article

Download full-text PDF

Source
http://bmcinfectdis.biomedcentral.com/articles/10.1186/1471-
Publisher Site
http://dx.doi.org/10.1186/1471-2334-8-134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2575207PMC
October 2008
12 Reads

Eustachian tube diverticulum chondroids and neck abscessation in a case of Streptococcus equi subsp. equi.

J S Afr Vet Assoc 2007 Sep;78(3):166-70

Department of Companion Animal Clinical Studies, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort 0110, South Africa.

A 12-year-old, grey, crossbred pony mare was presented with a swelling in the neck over the area of the 2nd cervical vertebra (C2), which was found to be painful on palpation. The neck was held stiffly. Radiography of the cervical region showed a focal area of increased radio-opacity over the dorsal, caudal and lateral aspect of the dorsal spinous process of C2. Read More

View Article

Download full-text PDF

Source
September 2007
2 Reads

[Seromucous otitis].

Ann Otolaryngol Chir Cervicofac 2007 Jul;124(3):120-5

Service d'otorhinolaryngologie et de chirurgie de la face et du cou, hôpital Lariboisière, 2 rue Ambroise-Paré, 75475 Paris cedex 10, France.

Objectives: Otitis media with effusion are defined as the persistence of middle ear effusion for more than 3 weeks. If the diagnostic is easy, questions remain about pathogeny and treatment.

Materials And Methods: Literature was reviewed regarding the pathogeny and the best treatment strategy. Read More

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S0003438X0700021
Publisher Site
http://dx.doi.org/10.1016/j.aorl.2006.10.007DOI Listing
July 2007
12 Reads

Tissular changes induced by Pseudomonas aeruginosa in an otitis media rat model with tubal obstruction.

Acta Otolaryngol 2007 Feb;127(2):132-7

Department of Otorhinolaryngology, Hospital Universitario Puerta de Hierro, Madrid, Spain.

Conclusions: This is a suitable model for the study of different features of middle ear inflammation. This model allows manipulations inside the middle ear while preserving relevant structures such as the tympanic membrane, and provides a useful model for the study of interactions between bacterial infection and eustachian tube dysfunction.

Objectives: Analysis of early and late histological features in an experimental model of Pseudomonas aeruginosa middle ear inoculation in the rat designed for the study of middle ear procedures. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/00016480600749994DOI Listing
February 2007
2 Reads

What is new in otitis media?

Authors:
Lucien Corbeel

Eur J Pediatr 2007 Jun 16;166(6):511-9. Epub 2007 Mar 16.

Department of Pediatrics, University Hospital, Herestraat 49, Leuven, Belgium.

The "wait and see" approach in acute otitis media (AOM), consisting of postponing the antibiotic administration for a few days, has been advocated mainly to counteract the increased bacterial resistance in respiratory infections. This approach is not justified in children less than 2 years of age and this for several reasons. First, AOM is an acute inflammation of the middle ear caused in about 70% of cases by bacteria. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00431-007-0461-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1876255PMC

Atypical manifestations of feline inflammatory polyps in three cats.

J Feline Med Surg 2007 Jun 22;9(3):219-25. Epub 2007 Jan 22.

Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.

Inflammatory polyps of the feline middle ear and nasopharynx are non-neoplastic masses that are presumed to originate from the epithelial lining of the tympanic bulla or Eustachian tube. The exact origin and cause are unknown, however, it is thought that inflammatory polyps arise as a result of a prolonged inflammatory process. It is unclear whether this inflammation initiates or potentiates the development and growth of inflammatory polyps. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jfms.2006.11.004DOI Listing
June 2007
1 Read

Autoinflation for hearing loss associated with otitis media with effusion.

Cochrane Database Syst Rev 2006 Oct 18(4):CD006285. Epub 2006 Oct 18.

Institute of Health Sciences, Department of Primary Health Care, Old Road, Headington, Oxford, UK.

Background: Otitis media with effusion (OME) or 'glue ear' is an accumulation of fluid in the middle ear, in the absence of acute inflammation or infection. It is the commonest cause of acquired hearing loss in childhood and the usual reason for insertion of 'grommets'. Potential treatments include decongestants, mucolytics, steroids, antihistamines and antibiotics. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/14651858.CD006285DOI Listing
October 2006
1 Read

Standing surgical removal of inspissated guttural pouch exudate (chondroids) in ten horses.

Vet Surg 2006 Oct;35(7):658-62

Department of Veterinary Clinical Sciences, Equine Referral Hospital, Royal Veterinary College, Hawkshead Lane, North Mymms, UK.

Objective: To report use of a modified Whitehouse approach in standing horses for management of inspissated guttural pouch empyema.

Study Design: Retrospective study.

Animals: Adult horses (n=10) with guttural pouch empyema. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1532-950X.2006.00204.xDOI Listing
October 2006
13 Reads
1.041 Impact Factor

[Allergic rhinitis. Coexistent diseases and complications. A review and analysis].

Rev Alerg Mex 2006 Jan-Feb;53(1):9-29

FAAAI, Inmunólogo, alergólogo y pediatra del Instituto Privado de Alergia, Inmunología y Vías Respiratorias de Córdoba, Veracruz, México.

Allergic rhinitis (AR) is rarely found in isolation and needs to be considered in the context of systemic allergic disease associated with numerous comorbid disorders, including asthma, chronic middle ear effusions, sinusitis, and lymphoid hypertrophy with obstructive sleep apnea, disordered sleep, and consequent behavioral and educational effects. The coexistence of allergic rhinitis and asthma is complex. First, the diagnosis of asthma may be confused by symptoms of cough caused by rhinitis and postnasal drip. Read More

View Article

Download full-text PDF

Source
May 2006
2 Reads

Laser fenestration of the mesial septum for treatment of guttural pouch chondroids in a pony.

Vet Surg 2005 Jul-Aug;34(4):383-6

Clinic for Horses, University of Veterinary Medicine, Hannover, Germany.

Objective: To describe removal of guttural pouch chondroids through a laser fenestrated mesial septum in a pony with an obstructed pharyngeal ostium of the left guttural pouch.

Study Design: Case report.

Animals: Pony. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/j.1532-950X.2005.00058.x
Publisher Site
http://dx.doi.org/10.1111/j.1532-950X.2005.00058.xDOI Listing
January 2006
12 Reads

Nasal prostaglandin challenge increases N2O exchange from blood to middle ear.

Auris Nasus Larynx 2005 Mar;32(1):29-32

Department of Pediatric Otolaryngology, Children's Hospital of Pittsburgh and Department of Otolaryngology, University of Pittsburgh School of Medicine, 3705 Fifth Ave. at DeSoto Street, Pittsburgh, PA 15213, USA.

Nasal inflammation (NI) resulting from allergy or virus infection is causally associated with otitis media. Impaired Eustachian tube (ET) function consequent to NI may mediate this relationship. Moreover, the functional demand placed upon the ET for gas supply may be increased by NI, a hypothesis tested here. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.anl.2004.11.008DOI Listing
March 2005
1 Read

[Mucociliary transport in Eustachian tubes in chronic suppurative otitis media].

Srp Arh Celok Lek 2004 May-Jun;132(5-6):148-51

Eustachian tube dysfunction is one of the well-known factors leading to development of chronic suppurative otitis media. Tube mucociliary transport is important for elimination of the inflammation products from the middle ear enabling recovery of the affected mucosa of the middle ear, local circulation and restoration of normal air pressure in the middle ear. The study was aimed at determining: 1. Read More

View Article

Download full-text PDF

Source
November 2004
2 Reads

What is your diagnosis? Guttural pouch empyema.

J Am Vet Med Assoc 2004 Mar;224(6):837-8

San Luis Rey Equine Hospital, 4211 Holly Ln, Bonsall, CA 92003, USA.

View Article

Download full-text PDF

Source
March 2004
7 Reads

[Clinical characteristics of the tympanic membrane retraction pocket].

Srp Arh Celok Lek 2003 May-Jun;131(5-6):221-5

Institute of Otorhinolaryngology and Maxillofacial Surgery, Clinical Centre of Serbia, Pasterova 2, 11000 Beograd.

Development of the eardrum retraction pocket, as pathologic finding, depends on Eustachian tube dysfunction, onset of the middle ear infection and site of development of retraction on the eardrum. The study is aimed at: 1. Determining the incidence of eardrum retraction pocket and cholesteatoma within it, as well as at the degree of eardrum retraction; 2. Read More

View Article

Download full-text PDF

Source
January 2004
3 Reads

Empyema of the guttural pouch (auditory tube diverticulum) in horses: 91 cases (1977-1997).

J Am Vet Med Assoc 1999 Dec;215(11):1666-70

Department of Large Animal Medicine and Surgery, College of Veterinary Medicine, Texas A&M University, College Station, TX 77843-4475, USA.

Objective: To identify features of guttural pouch (auditory tube diverticulum) empyema in horses and compare findings of uncomplicated guttural pouch empyema with guttural pouch empyema complicated by chondroids.

Design: Retrospective study.

Animals: 91 horses with guttural pouch empyema. Read More

View Article

Download full-text PDF

Source
December 1999
2 Reads

Diseases of the guttural pouches.

Vet Clin North Am Equine Pract 2003 Apr;19(1):123-58, vii

Department of Veterinary Clinical Sciences, The Ohio State University, 601 Vernon L. Tharp Street, Columbus, OH 43210, USA.

Guttural pouches are unique anatomic structures in Equidae. Conditions affecting the guttural pouches present with clinical signs that are not observed in other domestic species, and treatment of some of these conditions can be challenging. This article describes the anatomy and examination of the guttural pouches and reviews the presenting signs and treatment of the more common conditions affecting them, including empyema, tympany, mycosis, and stylohyoid arthropathy. Read More

View Article

Download full-text PDF

Source
April 2003
3 Reads

Model-based evaluation of eustachian tube mechanical properties using continuous pressure-flow rate data.

Ann Biomed Eng 2002 Sep;30(8):1064-76

Department of Chemical Engineering, Department of Pediatric Otolaryngology, Children's Hospital of Pittsburgh, Rm 8152, Rangos Research Center, 3460 Fifth Ave, Pittsburgh, PA 15213, USA.

Eustachian tube (ET) dysfunction has been implicated in the development of chronic otitis media, a common childhood disorder. An impaired ability to open the collapsible ET results in fluid accumulation in the middle ear and subsequent infection and inflammation. Abnormal ET function has been casually related to an abnormal mechanical environment. Read More

View Article

Download full-text PDF

Source
September 2002

[Relation between size of the nasopharynx and occurrence of chronic otitis media].

Srp Arh Celok Lek 2002 May-Jun;130 Suppl 1:12-5

Department of Oto-Rhino-Laryngology, Medical Centre, Kragujevac.

Aetiopathogenesis of chronic middle ear inflammation has not yet been sufficiently elucidated. Eustachian tube infection, causative organism virulence, immune status and biologically predisposed middle ear mucosa play the major role. The study was aimed at evaluation of the correlation between nasopharyngeal size and development of chronic middle ear inflammations. Read More

View Article

Download full-text PDF

Source
December 2002
1 Read

Cellular proliferation of mucosa-associated lymphoid tissue with otitis media: a preliminary study.

Ann Otol Rhinol Laryngol 2002 Oct;111(10):926-32

Department of Otolaryngology, University of Pittsburgh School of Medicine, Pennsylvania 15213, USA.

Histopathologic and immunohistochemical analyses were used to investigate the cellular proliferation of mucosa-associated lymphoid tissue (MALT) in human temporal bones with and without evidence of otitis media (OM). Anti-proliferating cell nuclear antigen (PCNA) antibody (clone PC10) was applied after the antigen retrieval procedure. Positive PCNA expression was observed in temporal bones that had been stored for 10 to 31 years in 80% ethanol. Read More

View Article

Download full-text PDF

Source
http://journals.sagepub.com/doi/10.1177/000348940211101012
Publisher Site
http://dx.doi.org/10.1177/000348940211101012DOI Listing
October 2002
3 Reads

A rat model of otitis media with effusion caused by eustachian tube obstruction with and without Streptococcus pneumoniae infection: methods and disease course.

Otolaryngol Head Neck Surg 2002 May;126(5):490-8

Department of Otolaryngology, Children's Hospital of Pittsburgh, PA 15213, USA.

Objective: To describe the clinical and histopathologic progression of a rat model of otitis media with effusion caused by eustachian tube obstruction (ETO) with and without Streptococcus pneumoniae infection.

Methods: In 164 rats, the left, bony eustachian tube was approached via a ventral incision and obstructed with dental material. Then 108 rats were infected via an intrabullar injection with S pneumoniae. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1067/mhn.2002.124935DOI Listing
May 2002
6 Reads

[Inflammation and acute otitis media].

Authors:
C Dubreuil

Presse Med 2001 Dec 22-29;30(39-40 Pt 2):19-25

Unlabelled: 1. EPITHELIUM OF THE MIDDLE EAR: The middle ear has a respiratory type epithelium. The mucus is produced by mucosal and by submucosal cells in the Eustachian tube. Read More

View Article

Download full-text PDF

Source
February 2002

Microdialysis studies of the middle ear distribution kinetics of amoxicillin in the awake chinchilla.

J Pharm Sci 2001 Dec;90(12):2088-98

Department of Pharmaceutics, College of Pharmacy, University of Minnesota, 308 Harvard Street S.E., Minneapolis, Minnesota 55455, USA.

This work was performed to develop an experimental animal model for the study of antibiotic drug distribution into middle ear fluid (MEF) and to evaluate its relevance and significance to the clinical treatment of otitis media (OM). Chinchillas were assigned to normal or infected ear groups after Eustachian tube obstruction (ETO) or direct trans-bullar inoculation with type 3 Streptococcus pneumoniae. Following survival surgery to implant microdialysis (MD) probes in the jugular vein and middle ear (ME), amoxicillin was given intravenously (iv) as a bolus or infusion. Read More

View Article

Download full-text PDF

Source
December 2001
3 Reads

Packing in endonasal surgery.

Am J Otolaryngol 2001 Sep-Oct;22(5):306-20

Department of ENT-Head and Neck Surgery, Marienhospital, Stuttgart, Germany.

Nasal packing is used to control bleeding in epistaxis and after endonasal surgery, for internal stabilization, and to prevent synechiae or restenosis, particularly after surgery. Generally accepted standards regarding the materials that should be used for packing, how long the packing should be left in place, or the indications for nasal packing are lacking. In view of the present lack of standardization and the many different packing materials used, we review the currently available materials and outline their respective properties, indications, and risks. Read More

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S019607090137747
Publisher Site
http://dx.doi.org/10.1053/ajot.2001.26499DOI Listing
November 2001
1 Read

Effect of intranasal challenge with interleukin-6 on upper airway symptomatology and physiology in allergic and nonallergic patients.

Ann Allergy Asthma Immunol 2001 May;86(5):531-6

Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pennsylvania 15213, USA.

Background: Interleukin-6 (IL-6) is a potent regulator of airway inflammation and an important component of biologic homeostasis. Previously, a temporal relationship between the local elaboration of IL-6 and the development of upper airway symptoms and pathophysiologic findings was reported for patients experimentally infected with influenza A virus or rhinovirus.

Objective: The objective of this study was to determine the provocative effects of direct, intranasal administration of IL-6 on those symptoms, signs, and pathophysiologic findings that accompany viral upper respiratory infection. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1081-1206(10)62901-8DOI Listing

Fistulation of the auditory tube diverticulum (guttural pouch) with a neodymium:yttrium-aluminum-garnet laser for treatment of chronic empyema in two horses.

J Am Vet Med Assoc 2001 Feb;218(3):405-7, 361

Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Purdue University, West Lafayette, IN 47907-1248, USA.

Two horses with chronic empyema of the auditory tube diverticulum (guttural pouch) were refractory to medical treatment; empyema was bilateral in 1 horse and unilateral in the other. Both horses were treated by fistulation of the cartilage of the pharyngeal orifice by use of a neodymium:yttrium-aluminum-garnet laser in a noncontact manner. To maintain patency of the fistulae, indwelling catheters were placed into the openings created by the laser. Read More

View Article

Download full-text PDF

Source
February 2001
1 Read